How popular is this Des Moines to Irvine flight route?

Flights from Des Moines to Irvine have been viewed 2 times in the past calendar month.

How long is the flight from Des Moines to Irvine?

Southwest, American Airlines, and United Airlines can get you from Des Moines to Irvine in just under 5h 35m. Your travel time can differ by up to 6h 36m. Airlines will cover a distance of 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines to fly from Des Moines to Irvine one-way?

To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $60. Frontier flights start at $73 while deals on Delta start at $110 one-way.

In terms of precipitation, rainfall in Irvine ranges from 0.0 - 3.4 inches per month. February is typically the wettest month, when rainfall can reach 3.4 in. July is typically the driest time to visit Irvine when rainfall is around 0.0 in.

If weather is an important factor for your trip to Irvine, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What are the cheapest flights from Des Moines to Irvine?

While on average a flight from Des Moines to Irvine is generally $328, our data shows the cheapest flight currently is $122. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $172 for that flight.

What are the most popular airlines that fly from Des Moines to Irvine?

The most popular airlines flying from Des Moines to Irvine are American Airlines, United Airlines and Southwest. Something to consider prior to booking your flight.

What airport do you fly from for flights from Des Moines to Irvine?

Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there is 1 daily outbound flight to Irvine from 6 different airlines.

Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Irvine?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.

Can I find deals for business class flights from Des Moines to Irvine?

Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$72+ Flights from Des Moines to Irvine

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in May or January, booked 80 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Thu 12/118:30 amDSM - LAX

1 stop13h 35mMultiple Airlines

Mon 1/126:26 amLAX - DSM

1 stop10h 56mMultiple Airlines

Deal found 12/3

$207

Wed 12/313:00 pmDSM - LAX

1 stop7h 31mMultiple Airlines

Mon 1/126:26 amLAX - DSM

1 stop10h 56mMultiple Airlines

Deal found 12/2

$232

Sat 12/208:29 pmDSM - LAX

1 stop13h 13mFrontier

Fri 12/262:07 pmLAX - DSM

1 stop27h 37mFrontier

Deal found 12/3

$238

Wed 12/313:00 pmDSM - LAX

1 stop7h 31mMultiple Airlines

Thu 1/89:46 pmLAX - DSM

1 stop15h 54mMultiple Airlines

Deal found 12/2

$239

Mon 12/228:29 pmDSM - LAX

1 stop6h 01mFrontier

Fri 12/262:07 pmLAX - DSM

1 stop27h 37mFrontier

Deal found 12/3

$244

Wed 12/313:00 pmDSM - LAX

1 stop7h 31mMultiple Airlines

Wed 1/73:42 pmLAX - DSM

2 stops28h 27mMultiple Airlines

Deal found 12/2

$265

Sat 12/208:29 pmDSM - LAX

1 stop13h 13mFrontier

Sat 12/276:34 amLAX - DSM

1 stop11h 10mFrontier

Deal found 12/2

$272

Fri 12/127:28 pmDSM - LAX

1 stop26h 37mMultiple Airlines

Sun 12/2110:03 pmLAX - DSM

1 stop19h 01mMultiple Airlines

Deal found 12/3

$300

Fri 12/127:58 pmDSM - LAX

1 stop24h 40mFrontier

Sun 12/148:51 pmLAX - DSM

1 stop20h 12mFrontier

Deal found 12/2

$302

Tue 12/308:30 amDSM - LAX

1 stop10h 34mMultiple Airlines

Tue 1/63:25 pmLAX - DSM

2 stops45h 38mMultiple Airlines

Deal found 12/2

$307

Mon 12/228:29 pmDSM - LAX

1 stop6h 01mFrontier

Sat 12/276:34 amLAX - DSM

1 stop11h 10mFrontier

Deal found 12/3

$308

Best flights from Des Moines to Irvine
Discover carefully curated flight deals from Des Moines to Irvine that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

Mon 1/268:35 amDSM - LAX

1 stop5h 35mSouthwest

Mon 2/29:55 amLAX - DSM

2 stops7h 25mSouthwest

Deal found 12/2

$253

Wed 1/215:24 amDSM - LAX

1 stop12h 11mAmerican Airlines

Sun 1/256:38 amLAX - DSM

1 stop5h 10mAmerican Airlines

Deal found 12/1

$277

Wed 4/18:00 amDSM - LAX

1 stop7h 30mUnited Airlines

Wed 4/157:00 amLAX - DSM

1 stop7h 09mUnited Airlines

Deal found 12/2

$295

Wed 4/295:15 pmDSM - LAX

1 stop9h 11mDelta

Fri 5/2912:45 amLAX - DSM

1 stop7h 30mDelta

Deal found 12/2

$295

Mon 1/194:40 pmDSM - LAX

1 stop7h 20mSouthwest

Mon 1/268:50 amLAX - DSM

1 stop8h 30mSouthwest

Deal found 12/3

$287

Tue 4/285:30 amDSM - LAX

1 stop5h 52mUnited Airlines

Tue 6/211:00 amLAX - DSM

1 stop7h 32mUnited Airlines

Deal found 12/2

$295

Tue 4/2810:55 amDSM - LAX

1 stop6h 07mDelta

Mon 6/19:50 pmLAX - DSM

1 stop10h 26mDelta

Deal found 12/2

$314

Wed 2/258:35 amDSM - LAX

2 stops7h 55mSouthwest

Sat 4/118:10 amLAX - DSM

2 stops7h 50mSouthwest

Deal found 12/1

$293

Tue 3/172:59 pmDSM - LAX

1 stop8h 50mUnited Airlines

Wed 3/254:13 pmLAX - DSM

1 stop5h 29mUnited Airlines

Deal found 12/3

$295

Wed 4/295:15 pmDSM - LAX

1 stop9h 11mDelta

Sun 5/3111:45 pmLAX - DSM

1 stop8h 30mDelta

Deal found 12/2

$314

Tue 1/69:03 amDSM - LAX

2 stops14h 45mUnited Airlines

Tue 1/612:30 amLAX - DSM

1 stop8h 25mUnited Airlines

Deal found 12/2

$308

Tue 3/312:25 pmDSM - LAX

1 stop8h 32mDelta

Sun 3/86:00 amLAX - DSM

1 stop8h 54mDelta

Deal found 12/4

$314

Last-minute flights from Des Moines to Irvine
Discover last-minute flight deals from Des Moines to Irvine. Data last updated December 4, 2025 and is based on user searches.

Mon 1/512:46 pmDSM - LAX

1 stop9h 45mMultiple Airlines

Mon 1/126:26 amLAX - DSM

1 stop10h 56mMultiple Airlines

Deal found 12/2

$135

Mon 1/512:46 pmDSM - LAX

1 stop9h 45mMultiple Airlines

Wed 1/73:25 pmLAX - DSM

1 stop22h 15mMultiple Airlines

Deal found 12/2

$146

Mon 1/58:29 pmDSM - LAX

1 stop18h 13mFrontier

Mon 1/126:26 amLAX - DSM

1 stop10h 56mFrontier

Deal found 12/3

$168

Mon 1/512:46 pmDSM - LAX

1 stop9h 45mMultiple Airlines

Sun 1/119:46 pmLAX - DSM

2 stops19h 36mMultiple Airlines

Deal found 12/2

$174

Fri 1/98:17 pmDSM - LAX

1 stop26h 11mFrontier

Thu 1/152:11 pmLAX - DSM

1 stop27h 12mFrontier

Deal found 12/4

$151

Sun 1/188:30 amDSM - LAX

1 stop12h 52mMultiple Airlines

Wed 1/211:56 pmLAX - DSM

2 stops30h 13mMultiple Airlines

Deal found 12/2

$173

One-way flights from Des Moines to Irvine
Search for one-way flight options from Des Moines to Irvine. Find affordable one-way fares based on user searches. Data last updated December 4, 2025.

Sun 3/17:36 pmDSM - LAX

1 stop15h 04mFrontier

Deal found 12/1

$72

Mon 1/512:46 pmDSM - LAX

1 stop9h 45mMultiple Airlines

Deal found 12/2

$74

Mon 2/28:30 amDSM - LAX

1 stop8h 42mMultiple Airlines

Deal found 12/2

$78

Tue 2/38:35 amDSM - LAX

1 stop5h 35mSouthwest

Deal found 12/4

$87

Thu 3/57:36 pmDSM - LAX

1 stop6h 54mFrontier

Deal found 12/3

$91

Sun 2/14:30 pmDSM - LAX

2 stops19h 55mMultiple Airlines

Deal found 12/2

$103

Find flight deals from Des Moines to Irvine

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$135 (Kiwi.com)
One-way from	$72 (Kiwi.com)
Popular in	March
Cheapest in	May
Average price	$436

Provider with most accurate pricing for Des Moines-Los Angeles flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.

Search Deals

From Des Moines to Irvine

Search Deals

One-way flight from Des Moines to Irvine

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 1/26

8:35 am-12:10 pm

1 stop5h 35m

Los Angeles

Mon 2/2

9:55 am-7:20 pm

2 stops7h 25m

$253

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

5:24 am-3:35 pm

1 stop12h 11m

Los Angeles

Sun 1/25

6:38 am-1:48 pm

1 stop5h 10m

$277

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 1/19

4:40 pm-10:00 pm

1 stop7h 20m

Los Angeles

Mon 1/26

8:50 am-7:20 pm

1 stop8h 30m

$287

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 2/25

8:35 am-2:30 pm

2 stops7h 55m

Los Angeles

Sat 4/11

8:10 am-6:00 pm

2 stops7h 50m

$293

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 4/1

8:00 am-1:30 pm

1 stop7h 30m

Los Angeles

Wed 4/15

7:00 am-4:09 pm

1 stop7h 09m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 4/29

5:15 pm-12:26 am

1 stop9h 11m

Los Angeles

Fri 5/29

12:45 am-10:15 am

1 stop7h 30m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 4/28

5:30 am-9:22 am

1 stop5h 52m

Los Angeles

Tue 6/2

11:00 am-8:32 pm

1 stop7h 32m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 3/17

2:59 pm-9:49 pm

1 stop8h 50m

Los Angeles

Wed 3/25

4:13 pm-11:42 pm

1 stop5h 29m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 1/6

9:03 am-9:48 pm

2 stops14h 45m

Los Angeles

Tue 1/6

12:30 am-10:55 am

1 stop8h 25m

$308

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 4/28

10:55 am-3:02 pm

1 stop6h 07m

Los Angeles

Mon 6/1

9:50 pm-10:16 am

1 stop10h 26m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 21 results

Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Irvine?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in July is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IR9?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Irvine in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Des Moines to Irvine?

Travelers seeking maximum savings on their Des Moines to Irvine flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Des Moines to Irvine

The most flights from DSM to IR9 are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

Reviews of airlines servicing Irvine

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,250 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,011 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,066 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,047 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,091 reviews

Southwest

8.0

Very good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airport do you fly from for flights from Des Moines to Irvine?
Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there is 1 daily outbound flight to Irvine from 6 different airlines.
How popular is this Des Moines to Irvine flight route?
Flights from Des Moines to Irvine have been viewed 2 times in the past calendar month.
How long is the flight from Des Moines to Irvine?
Southwest, American Airlines, and United Airlines can get you from Des Moines to Irvine in just under 5h 35m. Your travel time can differ by up to 6h 36m. Airlines will cover a distance of 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines to fly from Des Moines to Irvine one-way?
To fly one-way, consider booking your trip with Allegiant Air, which is currently one of the cheapest options available, starting at $60. Frontier flights start at $73 while deals on Delta start at $110 one-way.
What are the cheapest flights from Des Moines to Irvine?
While on average a flight from Des Moines to Irvine is generally $328, our data shows the cheapest flight currently is $122. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $172 for that flight.
Can I find deals for flights from Des Moines to Irvine that include hotel bookings?
Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Irvine?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.
Can I find deals for business class flights from Des Moines to Irvine?
Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Irvine?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in July is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Des Moines to Irvine

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$108	Average$184	FlexibilityNo cancel fee	On-time88%
Frontier	Cheapest$149	Average$234	FlexibilityNo cancel fee	On-time62%
Southwest	Cheapest$213	Average$437	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$222	Average$413	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$239	Average$350	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$252	Average$393	FlexibilityNo cancel fee	On-time71%

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$72+ Cheap flights from Des Moines (DSM) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Irvine with Cheapflights

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3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in May or January, booked 80 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to IrvineExplore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

Find flight deals from Des Moines to Irvine

Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated December 4, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.

Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on November 28, 2025.

What is the cheapest month to book a flight from Des Moines to Irvine?

What is the cheapest time of day to fly from DSM to IR9?

Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

What is the cheapest day to fly from Des Moines to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Irvine. Price data was last updated on December 16, 2024.

Weekly flight availability from Des Moines to Irvine

Explore weekly flight availability from Des Moines to Irvine. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 4, 2025.

Reviews of airlines servicing Irvine

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Irvine?

How popular is this Des Moines to Irvine flight route?

How long is the flight from Des Moines to Irvine?

What are the cheapest airlines to fly from Des Moines to Irvine one-way?

What are the cheapest flights from Des Moines to Irvine?

Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

How can I find direct flights from Des Moines to Irvine?

Can I find deals for business class flights from Des Moines to Irvine?

What is the cheapest month to book a flight from Des Moines to Irvine?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Irvine

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Des Moines to Irvine

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Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.