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$84+ Cheap flights from Des Moines (DSM) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in May or August, booked 69 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Irvine

Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated September 15, 2025.

Round-trip from

$149
(Priceline)

One-way from

$84
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$358
From Des Moines to Irvine
Search Deals
One-way flight from Des Moines to Irvine
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Priceline deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmDSM - LAX
1 stop7h 55mFrontier
Mon 11/36:44 amLAX - DSM
1 stop5h 03mFrontier
Deal found 9/12$149
This Frontier deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:32 pmDSM - LAX
1 stop11h 53mFrontier
Sun 11/166:44 amLAX - DSM
1 stop5h 03mFrontier
Deal found 9/12$159
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/292:25 pmDSM - LAX
1 stop7h 43mFrontier
Thu 10/26:35 amLAX - DSM
1 stop5h 05mFrontier
Deal found 9/13$172
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmDSM - LAX
1 stop7h 55mFrontier
Sun 11/25:44 amLAX - DSM
1 stop5h 03mFrontier
Deal found 9/14$180
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:25 pmDSM - LAX
1 stop12h 02mFrontier
Thu 10/96:44 amLAX - DSM
1 stop5h 08mFrontier
Deal found 9/14$182
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:32 pmDSM - LAX
1 stop11h 53mFrontier
Fri 11/146:44 amLAX - DSM
1 stop5h 05mFrontier
Deal found 9/14$186
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/22:25 pmDSM - LAX
1 stop12h 02mFrontier
Mon 10/66:35 amLAX - DSM
1 stop5h 05mFrontier
Deal found 9/13$188
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:32 pmDSM - LAX
1 stop11h 53mFrontier
Sun 11/96:44 amLAX - DSM
1 stop5h 03mFrontier
Deal found 9/13$193
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:25 pmDSM - LAX
1 stop7h 43mFrontier
Mon 9/296:35 amLAX - DSM
1 stop5h 05mFrontier
Deal found 9/15$197
This Frontier deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:32 pmDSM - LAX
1 stop7h 55mFrontier
Sun 11/96:44 amLAX - DSM
1 stop5h 03mFrontier
Deal found 9/14$198
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/192:37 pmDSM - LAX
1 stop18h 58mFrontier
Tue 10/216:45 amLAX - DSM
1 stop29h 07mFrontier
Deal found 9/13$202

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.

Fly from

Des Moines

Fly to

Irvine

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 2/17

6:25 am-10:10 am

1 stop5h 45m

Los Angeles

Tue 2/24

12:30 pm-7:20 pm

1 stop4h 50m

$277

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 1/26

3:20 pm-5:45 pm

Nonstop4h 25m

Los Angeles

Fri 1/30

11:59 pm-8:58 am

1 stop6h 59m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 11/1

3:30 pm-8:50 pm

1 stop7h 20m

Los Angeles

Sat 11/8

6:15 am-2:07 pm

1 stop5h 52m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 10/29

10:00 am-5:49 pm

1 stop9h 49m

Los Angeles

Wed 11/5

5:30 am-4:52 pm

1 stop9h 22m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Thu 10/30

2:40 pm-8:50 pm

1 stop8h 10m

Los Angeles

Tue 11/4

8:20 am-5:44 pm

1 stop7h 24m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 11/15

6:50 am-11:01 am

1 stop6h 11m

Los Angeles

Sat 12/6

5:25 am-4:58 pm

1 stop9h 33m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 10/21

2:13 pm-9:49 pm

1 stop9h 36m

Los Angeles

Tue 10/28

6:15 am-1:59 pm

1 stop5h 44m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 10/10

6:36 pm-11:59 pm

1 stop7h 23m

Los Angeles

Tue 10/14

7:00 am-4:17 pm

1 stop7h 17m

$296

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 11/4

8:20 am-11:55 am

1 stop5h 35m

Los Angeles

Fri 11/7

10:35 am-11:35 pm

1 stop11h 00m

$301

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Thu 11/13

5:45 am-9:40 am

1 stop5h 55m

Los Angeles

Sun 11/16

12:25 am-10:30 am

1 stop8h 05m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 19 results
1
2

Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on September 12, 2025.

The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Irvine?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $246). Flying from Des Moines to Irvine in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IR9?

Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Des Moines to Irvine, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Des Moines to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Irvine. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Irvine flight should consider departing on Friday mornings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated September 15, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Food

7.0

Crew

8.6

Comfort

8.0

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Irvine?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there are 0 daily outbound flights to Irvine from 6 different airlines.

  • How popular is this Des Moines to Irvine flight route?

    Flights from Des Moines to Irvine have been viewed 2 times in the past calendar month.

  • How long is the flight from Des Moines to Irvine?

    Southwest, American Airlines, and Delta can get you from Des Moines to Irvine in just under 4h 25m. Your travel time can differ by up to 2h 55m. Airlines will cover a distance of 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Des Moines to Irvine?

    While on average a flight from Des Moines to Irvine is generally $583, our data shows the cheapest flight currently is $130. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $227 for that flight.

  • Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

    Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.

  • Can I find deals for business class flights from Des Moines to Irvine?

    Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Irvine?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $246). Flying from Des Moines to Irvine in March is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 6 airlines flying from Des Moines to Irvine

Discover the top 6 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$207FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$108Average$199FlexibilityNo cancel feeOn-time88%
DeltaCheapest$130Average$354FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$222Average$429FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$286Average$403FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$332Average$442FlexibilityNo cancel feeOn-time63%

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