$86+ Cheap flights from Des Moines (DSM) to Irvine, CA
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/27. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Apr 22 — Apr 291
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Irvine with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in January or April, booked 80 days in advance, depart on a Wednesday or Thursday and return on a Thursday
Cheap flight deals from Des Moines to Irvine
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to IrvineExplore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:16 pm
DSM
- LAX
1 stop12h 00m
Frontier
Wed 5/136:30 am
LAX
- DSM
1 stop5h 01m
Frontier
Deal found 3/22![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1310:01 pm
DSM
- LAX
1 stop13h 24m
Multiple Airlines
Tue 7/2112:14 pm
LAX
- DSM
1 stop22h 45m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$215
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:55 pm
DSM
- LAX
1 stop5h 15m
Southwest
Tue 6/97:55 am
LAX
- DSM
1 stop5h 10m
Southwest
Deal found 3/22![Southwest logo]()
$222
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:14 pm
DSM
- LAX
1 stop5h 58m
Frontier
Fri 4/176:15 am
LAX
- DSM
1 stop4h 54m
Frontier
Deal found 3/19![Frontier logo]()
$225
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- LAX
1 stop12h 07m
Frontier
Fri 4/246:15 am
LAX
- DSM
1 stop4h 54m
Frontier
Deal found 3/22![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:30 am
DSM
- LAX
1 stop25h 51m
Multiple Airlines
Thu 4/94:07 pm
LAX
- DSM
1 stop27h 14m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$234
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
- LAX
1 stop27h 16m
Frontier
Thu 4/232:44 pm
LAX
- DSM
1 stop20h 25m
Frontier
Deal found 3/22![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:50 pm
DSM
- LAX
1 stop13h 35m
Multiple Airlines
Mon 8/3112:14 pm
LAX
- DSM
1 stop5h 50m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$239
Best flights from Des Moines to IrvineDiscover carefully curated flight deals from Des Moines to Irvine that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
Discover carefully curated flight deals from Des Moines to Irvine that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 23, 2026.
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
DSM
- LAX
1 stop5h 50m
Southwest
Sat 5/91:20 pm
LAX
- DSM
1 stop5h 35m
Southwest
Deal found 3/18![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:44 pm
DSM
- LAX
1 stop9h 17m
Delta
Wed 5/611:59 pm
LAX
- DSM
1 stop8h 17m
Delta
Deal found 3/18![Delta logo]()
$291
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
DSM
- LAX
1 stop12h 07m
Frontier
Sun 4/262:44 pm
LAX
- DSM
1 stop20h 25m
Frontier
Deal found 3/22![Frontier logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:14 pm
DSM
- LAX
1 stop20h 08m
Multiple Airlines
Sun 4/268:58 pm
LAX
- DSM
2 stops14h 11m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$386
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/306:33 pm
DSM
- LAX
1 stop5h 21m
American Airlines
Mon 4/69:00 am
LAX
- DSM
Nonstop3h 32m
American Airlines
Deal found 3/22![American Airlines logo]()
$423
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:15 pm
DSM
- LAX
2 stops8h 45m
Southwest
Wed 5/1310:45 am
LAX
- DSM
2 stops8h 30m
Southwest
Deal found 3/21![Southwest logo]()
$301
This Delta deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:28 pm
DSM
- LAX
1 stop6h 03m
Delta
Mon 6/110:35 pm
LAX
- DSM
1 stop9h 11m
Delta
Deal found 3/21![Delta logo]()
$357
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 pm
DSM
- LAX
1 stop6h 05m
Southwest
Thu 4/25:30 am
LAX
- DSM
2 stops8h 10m
Southwest
Deal found 3/18![Southwest logo]()
$409
Last-minute flights from Des Moines to IrvineDiscover last-minute flight deals from Des Moines to Irvine. Data last updated March 23, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Irvine. Data last updated March 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/39:45 pm
DSM
- LAX
1 stop17h 13m
Multiple Airlines
Wed 4/81:39 pm
LAX
- DSM
1 stop26h 22m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:30 am
DSM
- LAX
1 stop25h 51m
Multiple Airlines
Thu 4/94:07 pm
LAX
- DSM
1 stop27h 14m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/57:30 am
DSM
- LAX
1 stop25h 51m
Multiple Airlines
Wed 4/81:39 pm
LAX
- DSM
1 stop26h 22m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:11 pm
DSM
- LAX
1 stop16h 47m
Multiple Airlines
Fri 4/171:19 pm
LAX
- DSM
1 stop6h 05m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$246
This Frontier deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:14 pm
DSM
- LAX
1 stop5h 58m
Frontier
Fri 4/176:15 am
LAX
- DSM
1 stop4h 54m
Frontier
Deal found 3/19![Frontier logo]()
$225
This Expedia deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- LAX
1 stop12h 07m
Frontier
Fri 4/246:15 am
LAX
- DSM
1 stop4h 54m
Frontier
Deal found 3/22![Frontier logo]()
$230
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
- LAX
1 stop27h 16m
Frontier
Thu 4/232:44 pm
LAX
- DSM
1 stop20h 25m
Frontier
Deal found 3/22![Frontier logo]()
$236
This CheapOair deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
- LAX
1 stop27h 16m
Frontier
Sun 4/262:44 pm
LAX
- DSM
1 stop20h 25m
Frontier
Deal found 3/22![Frontier logo]()
$292
One-way flights from Des Moines to IrvineSearch for one-way flight options from Des Moines to Irvine. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
Search for one-way flight options from Des Moines to Irvine. Find affordable one-way fares based on user searches. Data last updated March 23, 2026.
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:04 pm
DSM
- LAX
1 stop12h 07m
Frontier
Deal found 3/20![Frontier logo]()
$86
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:16 pm
DSM
- LAX
1 stop12h 00m
Frontier
Deal found 3/22![Frontier logo]()
$87
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:04 pm
DSM
- LAX
1 stop27h 16m
Frontier
Deal found 3/20![Frontier logo]()
$88
This Frontier deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:23 pm
DSM
- LAX
1 stop5h 48m
Frontier
Deal found 3/18![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:14 pm
DSM
- LAX
1 stop20h 01m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$126
This Frontier deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:16 pm
DSM
- LAX
1 stop12h 00m
Frontier
Deal found 3/20![Frontier logo]()
$131
This Super.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/278:21 pm
DSM
- LAX
1 stop5h 55m
Frontier
Deal found 3/22![Frontier logo]()
$132
This Priceline deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:21 pm
DSM
- LAX
1 stop5h 55m
Frontier
Deal found 3/22![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:56 pm
DSM
- LAX
1 stop21h 22m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$136
Find flight deals from Des Moines to Irvine
Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated March 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $185 (Expedia) |
One-way from | $86 (Frontier) |
Popular in | December |
Cheapest in | January |
Average price | $373 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Sat 5/2
6:40 am-10:30 am
1 stop5h 50m
Los Angeles Los Angeles
Sat 5/9
1:20 pm-8:55 pm
1 stop5h 35m
$291
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Sat 5/2
2:44 pm-10:01 pm
1 stop9h 17m
Los Angeles Los Angeles
Wed 5/6
11:59 pm-10:16 am
1 stop8h 17m
$291
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Wed 5/6
3:15 pm-10:00 pm
2 stops8h 45m
Los Angeles Los Angeles
Wed 5/13
10:45 am-9:15 pm
2 stops8h 30m
$301
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Fri 4/24
2:04 pm-12:11 am
1 stop12h 07m
Los Angeles Los Angeles
Sun 4/26
2:44 pm-1:09 pm
1 stop20h 25m
$317
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Thu 5/28
5:28 pm-9:31 pm
1 stop6h 03m
Los Angeles Los Angeles
Mon 6/1
10:35 pm-9:46 am
1 stop9h 11m
$357
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Fri 4/24
10:14 pm-4:22 pm
1 stop20h 08m
Los Angeles Los Angeles
Sun 4/26
8:58 pm-1:09 pm
2 stops14h 11m
$386
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Wed 4/1
6:35 pm-10:40 pm
1 stop6h 05m
Los Angeles Los Angeles
Thu 4/2
5:30 am-3:40 pm
2 stops8h 10m
$409
Quickest round-trip
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Mon 3/30
6:33 pm-9:54 pm
1 stop5h 21m
Los Angeles Los Angeles
Mon 4/6
9:00 am-2:32 pm
Nonstop3h 32m
$423
Cheapest one-way
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Sat 5/2
2:44 pm-10:01 pm
1 stop9h 17m
$146
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Tue 4/21
1:32 pm-5:30 pm
1 stop5h 58m
$146
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Irvine
Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
DSM-LAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Irvine
DSM-IR9
DSM-LAX
How far ahead should I book a flight from Des Moines to Irvine?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on March 13, 2026.
The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Des Moines to Irvine?
Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $95). Flying from Des Moines to Irvine in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to IR9?
Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.
A simple way to save on the total cost of your ticket is to fly from Des Moines to Irvine in the evening. If you’re flexible enough to do this you can expect to save up to 85% on your trip compared to booking a flight in the morning.
Weekly flight availability from Des Moines to Irvine
Explore weekly flight availability from Des Moines to Irvine. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 23, 2026.
The most flights from DSM to IR9 are scheduled on a Saturday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
Reviews of airlines servicing Irvine
Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Irvine flights
Browse other Des Moines and Irvine flight options. Last updated on March 23, 2026.
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Des Moines to Irvine flights
Consider these flights traveling from Des Moines to Irvine.
Top 6 airlines flying from Des Moines to Irvine
Discover the top 6 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$172 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$149 | Average$238 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$208 | Average$384 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$213 | Average$427 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$222 | Average$395 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$365 | FlexibilityNo cancel fee | On-timeN/A |