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$54+ Cheap flights from Des Moines (DSM) to Irvine, CA

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in May or July, booked 80 days in advance, depart on a Friday or Monday and return on a Thursday

Cheap flight deals from Des Moines to Irvine

Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated October 14, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$194
(Kiwi.com)

One-way from

$54
(Frontier)

Popular in

March

Cheapest in

May

Average price

$361
Provider with most accurate pricing for Des Moines-Los Angeles flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.
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From Des Moines to Irvine
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One-way flight from Des Moines to Irvine
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Highest demand for flights based on searches. 8% potential increase in price ($33 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Des Moines to Irvine

Cheapest flights from Des Moines to Irvine
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:17 pmDSM - LAX
1 stop23h 52mMultiple Airlines
Wed 11/127:48 pmLAX - DSM
2 stops16h 08mMultiple Airlines
Deal found 10/14$207
This Frontier deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/32:32 pmDSM - LAX
1 stop7h 55mFrontier
Thu 11/66:44 amLAX - DSM
1 stop5h 12mFrontier
Deal found 10/13$212
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:32 pmDSM - LAX
1 stop19h 33mFrontier
Wed 11/127:48 pmLAX - DSM
2 stops16h 08mFrontier
Deal found 10/14$214
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:32 pmDSM - LAX
1 stop24h 46mFrontier
Sun 11/96:44 amLAX - DSM
1 stop29h 03mFrontier
Deal found 10/14$216
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:17 pmDSM - LAX
1 stop21h 27mMultiple Airlines
Fri 11/1411:56 amLAX - DSM
1 stop8h 44mMultiple Airlines
Deal found 10/14$234
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/243:48 pmDSM - LAX
1 stop23h 05mMultiple Airlines
Wed 12/33:35 pmLAX - DSM
1 stop21h 56mMultiple Airlines
Deal found 10/14$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.

Fly from

Des Moines

Fly to

Irvine

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 11/24

5:35 am-12:28 pm

1 stop8h 53m

Los Angeles

Thu 11/27

6:04 am-2:08 pm

1 stop6h 04m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/24

9:03 am-1:03 pm

1 stop6h 00m

Los Angeles

Mon 2/2

12:30 am-10:55 am

1 stop8h 25m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/24

1:20 pm-4:50 pm

1 stop5h 30m

Los Angeles

Tue 2/3

7:50 am-2:40 pm

1 stop4h 50m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 11/22

3:30 pm-9:05 pm

1 stop7h 35m

Los Angeles

Tue 12/2

11:40 pm-10:21 am

1 stop8h 41m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 1/6

6:20 am-2:55 pm

1 stop10h 35m

Los Angeles

Tue 1/13

12:15 pm-9:27 pm

1 stop7h 12m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 11/15

11:32 am-5:09 pm

1 stop7h 37m

Los Angeles

Sun 11/16

5:00 am-12:38 pm

1 stop5h 38m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 11/14

6:15 pm-11:00 pm

1 stop6h 45m

Los Angeles

Mon 11/17

2:15 pm-9:35 pm

1 stop5h 20m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 11/12

5:14 pm-8:47 pm

1 stop5h 33m

Los Angeles

Sun 11/16

5:00 am-12:38 pm

1 stop5h 38m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Thu 11/27

6:17 am-2:25 pm

1 stop10h 08m

Los Angeles

Thu 12/4

11:39 am-8:46 pm

1 stop7h 07m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sun 2/1

9:03 am-1:03 pm

1 stop6h 00m

Los Angeles

Fri 2/6

12:30 am-10:55 am

1 stop8h 25m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/14

Showing 1-10 of 22 results
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Best time to book a flight from Des Moines to Irvine

Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Irvine

How far ahead should I book a flight from Des Moines to Irvine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Irvine. Price data was last updated on October 10, 2025.

The price you pay for your flight from Des Moines to Irvine may vary depending on when you book. For the best chance of a lower fare, look to book 80 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to Irvine?

Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IR9?

Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

A simple way to save on the total cost of your ticket is to fly from Des Moines to Irvine in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Des Moines to Irvine?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to Irvine. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to Irvine flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Des Moines to Irvine?

Reviews of airlines servicing Irvine

Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated October 14, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
8.0
Very good
7,975 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
United Airlines
7.4
Good
8,976 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,042 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,135 reviews
Southwest
8.0
Very good
4,238 reviews

Comfort

8.0

Boarding

8.1

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Irvine. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Irvine?

    Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Irvine from Des Moines. Booking flights from Des Moines (DSM) to Irvine should be relatively easy as there is 1 daily outbound flight to Irvine from 6 different airlines.

  • How popular is this Des Moines to Irvine flight route?

    Flights from Des Moines to Irvine have been viewed 2 times in the past calendar month.

  • How long is the flight from Des Moines to Irvine?

    Delta, United Airlines, and Southwest can get you from Des Moines to Irvine in just under 5h 30m. Your travel time can differ by up to 3h 23m. Airlines will cover a distance of 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Des Moines to Irvine?

    While on average a flight from Des Moines to Irvine is generally $982, our data shows the cheapest flight currently is $137. When looking at the most popular route, (Des Moines - Los Angeles), you can expect to pay $244 for that flight.

  • Can I find deals for flights from Des Moines to Irvine that include hotel bookings?

    Yes. In addition to deals on Des Moines to Irvine flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Irvine?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Irvine.

  • Can I find deals for business class flights from Des Moines to Irvine?

    Yes. Cheapflights offers flight deals from Des Moines to Irvine by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Irvine?

    Currently, May is the cheapest month in which you can book a flight from Des Moines to Irvine (average of $101). Flying from Des Moines to Irvine in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Irvine

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Top 6 airlines flying from Des Moines to Irvine

Discover the top 6 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$108Average$243FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$108Average$198FlexibilityNo cancel feeOn-time88%
DeltaCheapest$130Average$342FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$222Average$411FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$252Average$399FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$294Average$431FlexibilityNo cancel feeOn-time63%

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