$92+ Cheap flights from Irvine, CA to Des Moines (DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — DSM
Jul 21 — Jul 281
Round-trip
1 adult, Economy
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Find cheap flights from Irvine to Des Moines with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Irvine to Des Moines are usually found in September or February, booked 47 days in advance, depart on a Tuesday or Thursday and return on a Wednesday
Cheap flight deals from Irvine to Des Moines
Cheapest
Best
Last-minute
One-way
Cheapest flights from Irvine to Des MoinesExplore the most affordable flight options available from Irvine to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
Explore the most affordable flight options available from Irvine to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 21, 2026.
This Expedia deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Mon 8/172:19 pm
DSM
- LAX
1 stop20h 36m
Frontier
Deal found 6/19![Frontier logo]()
$249
This CheapOair deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:35 pm
LAX
- DSM
1 stop17h 59m
Frontier
Mon 8/172:19 pm
DSM
- LAX
1 stop20h 36m
Frontier
Deal found 6/21![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
LAX
- DSM
1 stop12h 13m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- LAX
1 stop24h 02m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:27 pm
LAX
- DSM
1 stop18h 21m
Multiple Airlines
Mon 9/72:19 pm
DSM
- LAX
1 stop20h 36m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$252
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Fri 9/42:19 pm
DSM
- LAX
1 stop11h 52m
Frontier
Deal found 6/19![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:49 pm
LAX
- DSM
1 stop14h 45m
Frontier
Wed 7/222:19 pm
DSM
- LAX
1 stop28h 31m
Frontier
Deal found 6/19![Frontier logo]()
$259
This Expedia deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Mon 8/32:19 pm
DSM
- LAX
1 stop11h 52m
Frontier
Deal found 6/20![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:07 pm
LAX
- DSM
1 stop6h 36m
Multiple Airlines
Mon 7/2710:01 pm
DSM
- LAX
1 stop13h 24m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:47 am
LAX
- DSM
1 stop6h 54m
Multiple Airlines
Sun 9/139:56 pm
DSM
- LAX
1 stop22h 03m
Multiple Airlines
Deal found 6/17![Multiple Airlines logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:56 pm
LAX
- DSM
2 stops28h 47m
Multiple Airlines
Wed 7/291:49 pm
DSM
- LAX
1 stop8h 14m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:56 pm
LAX
- DSM
2 stops28h 47m
Multiple Airlines
Mon 8/310:01 pm
DSM
- LAX
1 stop24h 02m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$271
Best flights from Irvine to Des MoinesDiscover carefully curated flight deals from Irvine to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
Discover carefully curated flight deals from Irvine to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 21, 2026.
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:59 pm
LAX
- DSM
1 stop8h 19m
Delta
Tue 8/186:55 am
DSM
- LAX
1 stop8h 20m
Delta
Deal found 6/16![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/155:30 am
LAX
- DSM
1 stop6h 46m
United Airlines
Sat 8/295:45 am
DSM
- LAX
1 stop5h 47m
United Airlines
Deal found 6/18![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:10 am
LAX
- DSM
2 stops8h 10m
Southwest
Tue 7/287:00 pm
DSM
- LAX
1 stop5h 40m
Southwest
Deal found 6/17![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:55 am
LAX
- DSM
2 stops9h 05m
Southwest
Fri 8/72:25 pm
DSM
- LAX
2 stops6h 55m
Southwest
Deal found 6/17![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:25 am
LAX
- DSM
2 stops9h 35m
Southwest
Tue 8/187:15 am
DSM
- LAX
1 stop5h 10m
Southwest
Deal found 6/19![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:05 am
LAX
- DSM
2 stops8h 10m
Southwest
Sat 9/197:20 am
DSM
- LAX
2 stops9h 15m
Southwest
Deal found 6/16![Southwest logo]()
$386
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/158:10 am
LAX
- DSM
2 stops8h 10m
Southwest
Wed 7/223:45 pm
DSM
- LAX
2 stops8h 55m
Southwest
Deal found 6/18![Southwest logo]()
$424
This Southwest deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:10 am
LAX
- DSM
2 stops8h 10m
Southwest
Thu 7/236:10 am
DSM
- LAX
2 stops8h 35m
Southwest
Deal found 6/19![Southwest logo]()
$441
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1111:05 am
LAX
- DSM
2 stops8h 10m
Southwest
Sun 9/137:00 am
DSM
- LAX
2 stops6h 45m
Southwest
Deal found 6/16![Southwest logo]()
$465
This Southwest deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:05 am
LAX
- DSM
2 stops8h 55m
Southwest
Thu 8/62:25 pm
DSM
- LAX
2 stops6h 55m
Southwest
Deal found 6/18![Southwest logo]()
$474
This Southwest deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/411:05 am
LAX
- DSM
2 stops8h 10m
Southwest
Mon 9/72:25 pm
DSM
- LAX
2 stops6h 55m
Southwest
Deal found 6/17![Southwest logo]()
$487
Last-minute flights from Irvine to Des MoinesDiscover last-minute flight deals from Irvine to Des Moines. Data last updated June 21, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to Des Moines. Data last updated June 21, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:46 pm
LAX
- DSM
1 stop15h 48m
Frontier
Wed 7/152:19 pm
DSM
- LAX
1 stop28h 31m
Frontier
Deal found 6/17![Frontier logo]()
$273
This Expedia deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/106:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Mon 7/272:19 pm
DSM
- LAX
1 stop11h 52m
Frontier
Deal found 6/19![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:56 pm
LAX
- DSM
2 stops28h 47m
Multiple Airlines
Wed 7/222:19 pm
DSM
- LAX
1 stop11h 52m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$280
This Expedia deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Wed 7/222:19 pm
DSM
- LAX
1 stop28h 31m
Frontier
Deal found 6/18![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
LAX
- DSM
1 stop12h 13m
Multiple Airlines
Mon 7/2010:01 pm
DSM
- LAX
1 stop24h 02m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$251
This CheapOair deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/198:49 pm
LAX
- DSM
1 stop14h 45m
Frontier
Wed 7/222:19 pm
DSM
- LAX
1 stop28h 31m
Frontier
Deal found 6/19![Frontier logo]()
$259
This Expedia deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Mon 8/32:19 pm
DSM
- LAX
1 stop11h 52m
Frontier
Deal found 6/20![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:56 pm
LAX
- DSM
2 stops28h 47m
Multiple Airlines
Wed 7/291:49 pm
DSM
- LAX
1 stop8h 14m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:56 pm
LAX
- DSM
2 stops28h 47m
Multiple Airlines
Mon 8/310:01 pm
DSM
- LAX
1 stop24h 02m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2312:07 pm
LAX
- DSM
1 stop6h 36m
Multiple Airlines
Mon 7/2710:01 pm
DSM
- LAX
1 stop13h 24m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:30 am
LAX
- DSM
1 stop28h 29m
Multiple Airlines
Sun 8/29:33 pm
DSM
- LAX
1 stop13h 52m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:56 pm
LAX
- DSM
2 stops21h 03m
Multiple Airlines
Fri 7/3110:01 pm
DSM
- LAX
1 stop13h 24m
Multiple Airlines
Deal found 6/16![Multiple Airlines logo]()
$279
One-way flights from Irvine to Des MoinesSearch for one-way flight options from Irvine to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
Search for one-way flight options from Irvine to Des Moines. Find affordable one-way fares based on user searches. Data last updated June 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:07 pm
LAX
- DSM
1 stop22h 52m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:47 am
LAX
- DSM
1 stop6h 01m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:27 pm
LAX
- DSM
1 stop20h 39m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:15 pm
LAX
- DSM
1 stop26h 33m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$112
This Expedia deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Deal found 6/18![Frontier logo]()
$120
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Deal found 6/19![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:15 am
LAX
- DSM
1 stop11h 45m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$127
This Frontier deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:30 am
LAX
- DSM
1 stop5h 04m
Frontier
Deal found 6/17![Frontier logo]()
$128
Find flight deals from Irvine to Des Moines
Keep the following information in mind while searching for Irvine to Des Moines flight deals. Data was last updated June 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Expedia) |
One-way from | $92 (Kiwi.com) |
Popular in | June |
Cheapest in | September |
Average price | $454 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
Use the filters below to find and compare flights from Irvine to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Wed 8/12
11:59 pm-10:18 am
1 stop8h 19m
Des Moines
Tue 8/18
6:55 am-1:15 pm
1 stop8h 20m
$305
Quickest round-trip
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Sat 8/15
5:30 am-2:16 pm
1 stop6h 46m
Des Moines
Sat 8/29
5:45 am-9:32 am
1 stop5h 47m
$325
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Tue 7/21
8:10 am-6:20 pm
2 stops8h 10m
Des Moines
Tue 7/28
7:00 pm-10:40 pm
1 stop5h 40m
$331
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Tue 8/4
9:55 am-9:00 pm
2 stops9h 05m
Des Moines
Fri 8/7
2:25 pm-7:20 pm
2 stops6h 55m
$372
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Wed 8/12
9:25 am-9:00 pm
2 stops9h 35m
Des Moines
Tue 8/18
7:15 am-10:25 am
1 stop5h 10m
$381
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Fri 9/11
11:05 am-9:15 pm
2 stops8h 10m
Des Moines
Sat 9/19
7:20 am-2:35 pm
2 stops9h 15m
$386
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Wed 7/15
8:10 am-6:20 pm
2 stops8h 10m
Des Moines
Wed 7/22
3:45 pm-10:40 pm
2 stops8h 55m
$424
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Wed 7/22
8:10 am-6:20 pm
2 stops8h 10m
Des Moines
Thu 7/23
6:10 am-12:45 pm
2 stops8h 35m
$441
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Fri 9/11
11:05 am-9:15 pm
2 stops8h 10m
Des Moines
Sun 9/13
7:00 am-11:45 am
2 stops6h 45m
$465
Los AngelesDes Moines
LAX - DSM
LAXDSM
Los Angeles
Thu 7/30
5:05 am-4:00 pm
2 stops8h 55m
Des Moines
Thu 8/6
2:25 pm-7:20 pm
2 stops6h 55m
$474
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Irvine to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Irvine with our price prediction graph.
LAX-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Des Moines
IR9-DSM
LAX-DSM
What is the cheapest time of day to fly from IR9 to DSM?
Find hourly flight availability from Irvine to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 21, 2026.
When flying from Irvine to Des Moines, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from Irvine to Des Moines
Explore weekly flight availability from Irvine to Des Moines. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 21, 2026.
The most flights from IR9 to DSM are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Irvine to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated June 21, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Irvine to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Comfort
8.0
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Irvine to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Ames
Clive
Johnston
Boone
West Des Moines
Ankeny
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Complete your trip
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 21, 2026.
Search flights from Irvine to Des Moines by cabin class
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Irvine and Des Moines flights
Browse other Irvine and Des Moines flight options. Last updated on June 21, 2026.
Popular flight searches
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Irvine to Des Moines flights
Consider these flights traveling from Irvine to Des Moines.
Top 6 airlines flying from Irvine to Des Moines
Discover the top 6 airlines that operate flights from Irvine to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$192 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$188 | Average$258 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$213 | Average$429 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$260 | Average$417 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$264 | Average$470 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$285 | Average$362 | FlexibilityNo cancel fee | On-timeN/A |