$91+ Cheap flights from Des Moines (DSM) to Irvine, CA
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Oct 16 — Oct 231
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Irvine with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Irvine are usually found in April or January, booked 71 days in advance, depart on a Wednesday or Saturday and return on a Tuesday
Cheap flight deals from Des Moines to Irvine
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to IrvineExplore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
Explore the most affordable flight options available from Des Moines to Irvine. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop6h 04m
Thu 10/292:31 pm -
1 stop27h 04m
Deal found 9/16![Frontier logo]()
$202
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:30 pm -
Nonstop4h 12m
Tue 10/271:19 pm -
Nonstop3h 36m
Deal found 9/16![American Airlines logo]()
$213
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:51 pm -
1 stop6h 04m
Tue 10/277:10 am -
1 stop8h 59m
Deal found 9/16![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Tue 10/275:20 am -
2 stops7h 00m
Deal found 9/16![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop19h 05m
Tue 10/65:20 pm -
1 stop18h 32m
Deal found 9/11![Multiple Airlines logo]()
$242
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/178:05 pm -
Nonstop3h 55m
Tue 12/11:40 pm -
Nonstop3h 30m
Deal found 9/15![American Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
1 stop20h 52m
Thu 10/154:33 pm -
1 stop16h 24m
Deal found 9/11![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm -
1 stop12h 54m
Wed 12/29:59 pm -
1 stop22h 27m
Deal found 9/13![Multiple Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop19h 05m
Thu 10/154:33 pm -
1 stop16h 24m
Deal found 9/11![Multiple Airlines logo]()
$251
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop5h 25m
Tue 12/110:45 am -
2 stops8h 05m
Deal found 9/15![Southwest logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop6h 04m
Mon 10/2611:40 am -
1 stop5h 50m
Deal found 9/11![Frontier logo]()
$255
Best flights from Des Moines to IrvineDiscover carefully curated flight deals from Des Moines to Irvine that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
Discover carefully curated flight deals from Des Moines to Irvine that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:00 am -
1 stop6h 17m
Tue 12/17:01 am -
1 stop7h 12m
Deal found 9/15![United Airlines logo]()
$233
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
2 stops7h 25m
Tue 12/110:45 am -
2 stops8h 05m
Deal found 9/15![Southwest logo]()
$258
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:34 pm -
1 stop8h 03m
Sat 10/106:00 am -
1 stop6h 25m
Deal found 9/11![Delta logo]()
$435
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Mon 10/2611:35 am -
2 stops8h 45m
Deal found 9/15![Southwest logo]()
$352
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/215:12 pm -
1 stop5h 44m
Mon 12/2812:30 am -
1 stop8h 16m
Deal found 9/13![United Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:40 pm -
1 stop7h 00m
Sat 1/95:20 am -
1 stop5h 05m
Deal found 9/14![Southwest logo]()
$371
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop10h 26m
Sat 10/106:00 am -
1 stop6h 25m
Deal found 9/11![Delta logo]()
$435
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/133:25 pm -
1 stop7h 23m
Sat 2/2712:10 am -
1 stop8h 10m
Deal found 9/15![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:10 pm -
2 stops7h 00m
Thu 10/228:05 am -
1 stop8h 25m
Deal found 9/15![Southwest logo]()
$422
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/106:25 am -
1 stop5h 50m
Wed 3/179:15 am -
2 stops7h 15m
Deal found 9/12![Southwest logo]()
$432
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:40 am -
2 stops7h 10m
Mon 11/1611:50 am -
2 stops7h 00m
Deal found 9/13![Southwest logo]()
$472
Last-minute flights from Des Moines to IrvineDiscover last-minute flight deals from Des Moines to Irvine. Data last updated September 16, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Irvine. Data last updated September 16, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
1 stop20h 52m
Thu 10/154:33 pm -
1 stop16h 24m
Deal found 9/11![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:31 pm -
1 stop20h 52m
Tue 10/135:15 pm -
1 stop18h 37m
Deal found 9/11![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop19h 05m
Tue 10/65:20 pm -
1 stop18h 32m
Deal found 9/11![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:42 pm -
1 stop19h 05m
Thu 10/154:33 pm -
1 stop16h 24m
Deal found 9/11![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop6h 04m
Mon 10/2611:40 am -
1 stop5h 50m
Deal found 9/11![Frontier logo]()
$255
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:30 pm -
Nonstop4h 12m
Tue 10/271:19 pm -
Nonstop3h 36m
Deal found 9/16![American Airlines logo]()
$213
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:51 pm -
1 stop6h 04m
Tue 10/277:10 am -
1 stop8h 59m
Deal found 9/16![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Tue 10/275:20 am -
2 stops7h 00m
Deal found 9/16![Southwest logo]()
$238
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:30 pm -
Nonstop4h 12m
Tue 10/271:19 pm -
Nonstop3h 36m
Deal found 9/16![American Airlines logo]()
$243
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop6h 04m
Thu 10/292:31 pm -
1 stop27h 04m
Deal found 9/16![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:00 pm -
1 stop20h 16m
Tue 11/35:15 pm -
1 stop18h 40m
Deal found 9/14![Multiple Airlines logo]()
$261
One-way flights from Des Moines to IrvineSearch for one-way flight options from Des Moines to Irvine. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
Search for one-way flight options from Des Moines to Irvine. Find affordable one-way fares based on user searches. Data last updated September 16, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/149:18 pm -
1 stop19h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$91
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop6h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/112:45 pm -
1 stop19h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$106
This Super.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:30 pm -
1 stop5h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:04 pm -
1 stop22h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:25 pm -
1 stop19h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:04 pm -
1 stop22h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$114
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
1 stop5h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Southwest logo]()
$122
Find flight deals from Des Moines to Irvine
Keep the following information in mind while searching for Des Moines to Irvine flight deals. Data was last updated September 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (Cheapflightsfares) |
One-way from | $91 (Kiwi.com) |
Popular in | August |
Cheapest in | April |
Average price | $384 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Irvine that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
Use the filters below to find and compare flights from Des Moines to Irvine that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Thu 10/29
2:00 pm-9:05 pm
1 stop9h 05m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$137
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Sun 10/4
1:22 pm-7:47 am
1 stop20h 25m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$168
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Wed 12/16
11:01 am-4:49 pm
1 stop7h 48m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$177
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Wed 12/9
7:00 am-12:45 pm
2 stops7h 45m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$183
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Wed 11/25
5:40 pm-10:40 pm
1 stop7h 00m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$214
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Tue 3/9
12:15 pm-4:25 pm
1 stop6h 10m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$214
Quickest round-trip
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Wed 10/14
6:35 pm-10:05 pm
1 stop5h 30m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$214
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Tue 11/17
2:48 pm-4:13 pm
2 stops27h 25m
Los Angeles
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$221
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Tue 11/17
9:00 am-1:17 pm
1 stop6h 17m
Los Angeles
Tue 12/1
7:01 am-4:13 pm
1 stop7h 12m
$233
Des MoinesLos Angeles
DSM Des Moines - LAX Los Angeles
DSMLAX
Des Moines
Tue 11/17
7:00 am-12:25 pm
2 stops7h 25m
Los Angeles
Tue 12/1
10:45 am-8:50 pm
2 stops8h 05m
$258
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Irvine
Have a flexible travel schedule? Discover the best time to fly to Irvine from Des Moines with our price prediction graph.
DSM-LAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Irvine
DSM-IR9
DSM-LAX
What is the cheapest time of day to fly from DSM to IR9?
Find hourly flight availability from Des Moines to Irvine. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2026.
A simple way to save on the total cost of your ticket is to fly from Des Moines to Irvine at noon. If you’re flexible enough to do this you can expect to save up to 55% on your trip compared to booking a flight in the morning.
Weekly flight availability from Des Moines to Irvine
Explore weekly flight availability from Des Moines to Irvine. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2026.
The most flights from DSM to IR9 are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Des Moines to Irvine?
Airfare is below average for this route at the moment.
Des Moines to Irvine flights typically cost between $311 and $453 in October.The cheapest round-trip price found within the last 5 days was $202 on Frontier (Oct 26-Oct 29).
Reviews of airlines servicing Irvine
Get insights into the airlines that provide service to Irvine. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Irvine. Reviews last updated September 16, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Des Moines to Irvine. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Food
7.0
Boarding
8.1
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
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Top 7 airlines flying from Des Moines to Irvine
Discover the top 7 airlines that operate flights from Des Moines to Irvine. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$125 | Average$187 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$149 | Average$250 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$234 | Average$415 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$462 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$264 | Average$417 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$384 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$280 | Average$325 | FlexibilityNo cancel fee | On-time62% |