How long is the flight from Charleston to Des Moines?

For as low as $303, American Airlines can have you in Des Moines from Charleston in 6h 13m. The distance between Charleston and Des Moines is about 956 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Charleston to Des Moines round-trip?

Currently priced at $233, American Airlines will fly you from Charleston to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $236. American Airlines is 46% cheaper than the average price of flights available within the next 90 days to this destination.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

Most accurate provider : When it comes to deals on Charleston-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Charleston-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Charleston to Des Moines that include hotel bookings?

Yes. In addition to deals on Charleston to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Charleston to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Des Moines.

Can I find deals for business class flights from Charleston to Des Moines?

Yes. Cheapflights offers flight deals from Charleston to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$194+ Flights from Charleston to Des Moines

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Cheap flight deals from Charleston to Des Moines

Cheapest flights from Charleston to Des Moines
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Sun 12/216:00 amCHS - DSM

1 stop7h 48mAmerican Airlines

Tue 12/232:07 pmDSM - CHS

1 stop4h 21mAmerican Airlines

Deal found 12/6

$467

Best flights from Charleston to Des Moines
Discover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 7, 2025.

Tue 1/612:04 pmCHS - DSM

1 stop8h 54mAmerican Airlines

Thu 1/84:00 pmDSM - CHS

1 stop5h 34mAmerican Airlines

Deal found 12/4

$207

Thu 2/195:07 pmCHS - DSM

1 stop6h 13mUnited Airlines

Mon 2/233:24 pmDSM - CHS

1 stop5h 08mUnited Airlines

Deal found 12/4

$303

Last-minute flights from Charleston to Des Moines
Discover last-minute flight deals from Charleston to Des Moines. Data last updated December 7, 2025 and is based on user searches.

Sun 12/216:00 amCHS - DSM

1 stop7h 48mAmerican Airlines

Tue 12/232:07 pmDSM - CHS

1 stop4h 21mAmerican Airlines

Deal found 12/6

$467

Tue 1/612:04 pmCHS - DSM

1 stop8h 54mAmerican Airlines

Thu 1/84:00 pmDSM - CHS

1 stop5h 34mAmerican Airlines

Deal found 12/4

$207

One-way flights from Charleston to Des Moines
Search for one-way flight options from Charleston to Des Moines. Find affordable one-way fares based on user searches. Data last updated December 7, 2025.

Tue 12/162:59 pmCHS - DSM

2 stops20h 42mMultiple Airlines

Deal found 12/5

$194

Mon 12/153:33 pmCHS - DSM

2 stops44h 08mMultiple Airlines

Deal found 12/5

$205

Fri 12/192:28 pmCHS - DSM

1 stop4h 19mDelta

Deal found 12/5

$234

Fri 12/196:44 amCHS - DSM

2 stops9h 40mAmerican Airlines

Deal found 12/5

$239

Sun 12/214:59 pmCHS - DSM

1 stop5h 41mUnited Airlines

Deal found 12/6

$269

Mon 12/1511:33 amCHS - DSM

1 stop6h 51mUnited Airlines

Deal found 12/5

$309

Thu 12/186:44 amCHS - DSM

2 stops9h 40mAmerican Airlines

Deal found 12/5

$314

Sat 12/202:46 pmCHS - DSM

2 stops10h 05mAmerican Airlines

Deal found 12/5

$339

Find flight deals from Charleston to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$207 (American Airlines)
One-way from	$194 (Kiwi.com)
Popular in	February
Cheapest in	January
Average price	$449

Provider with most accurate pricing for Charleston-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Charleston-Des Moines flights.

Search Deals

From Charleston to Des Moines

Search Deals

One-way flight from Charleston to Des Moines

Search Deals

Highest demand for flights based on searches. 20% potential increase in price ($110 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($30 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Tue 1/6

12:04 pm-7:58 pm

1 stop8h 54m

Des Moines

Thu 1/8

4:00 pm-10:34 pm

1 stop5h 34m

$207

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 2/19

5:07 pm-10:20 pm

1 stop6h 13m

Des Moines

Mon 2/23

3:24 pm-9:32 pm

1 stop5h 08m

$303

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Tue 12/16

2:59 pm-10:41 am

2 stops20h 42m

$194

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Mon 12/15

3:33 pm-10:41 am

2 stops44h 08m

$205

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 12/19

6:44 am-1:21 pm

1 stop7h 37m

$234

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Thu 12/18

2:55 pm-7:43 pm

1 stop5h 48m

$234

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Fri 12/19

2:28 pm-5:47 pm

1 stop4h 19m

$234

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Sat 12/20

5:58 pm-10:31 pm

1 stop5h 33m

$234

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

Sun 12/21

4:59 pm-9:40 pm

1 stop5h 41m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/5

Compare providers for flights from Charleston to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Charleston-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Charleston-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Charleston-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Charleston-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Charleston to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Des Moines

What is the cheapest month to book a flight from Charleston to Des Moines?

Currently, September is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $162). Flying from Charleston to Des Moines in February is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to DSM?

When flying from Charleston to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 15% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Delta and American Airlines from Charleston to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,013 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,046 reviews

Delta

7.9

Good

8,013 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Charleston to Des Moines?
For as low as $303, American Airlines can have you in Des Moines from Charleston in 6h 13m. The distance between Charleston and Des Moines is about 956 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Charleston to Des Moines round-trip?
Currently priced at $233, American Airlines will fly you from Charleston to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on Delta for as low as $236. American Airlines is 46% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Charleston to Des Moines that include hotel bookings?
Yes. In addition to deals on Charleston to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Charleston to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Des Moines.
Can I find deals for business class flights from Charleston to Des Moines?
Yes. Cheapflights offers flight deals from Charleston to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Charleston to Des Moines?
Currently, September is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $162). Flying from Charleston to Des Moines in February is currently the most expensive (average of $387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Johnston

Altoona

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West Des Moines

Ankeny

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Other flights to Des Moines

Top 2 airlines flying from Charleston to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$233	Average$366	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$236	Average$418	FlexibilityNo cancel fee	On-timeN/A

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$194+ Cheap flights from Charleston to Des Moines (CHS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Charleston to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Charleston to Des Moines

Cheapest flights from Charleston to Des MoinesExplore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.

Find flight deals from Charleston to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.

Compare providers for flights from Charleston to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in December.

Best time to book a flight from Charleston to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Des Moines

What is the cheapest month to book a flight from Charleston to Des Moines?

What is the cheapest time of day to fly from CHS to DSM?

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Delta and American Airlines from Charleston to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Charleston to Des Moines?

What are the cheapest airlines flying from Charleston to Des Moines round-trip?

Can I find deals for flights from Charleston to Des Moines that include hotel bookings?

How can I find direct flights from Charleston to Des Moines?

Can I find deals for business class flights from Charleston to Des Moines?

What is the cheapest month to book a flight from Charleston to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Charleston to Des Moines

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Top 2 airlines flying from Charleston to Des Moines

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Cheapest flights from Charleston to Des Moines
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 7, 2025.