$167+ Cheap flights from Charleston to Des Moines (CHS - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
jun. 10 — jun. 171
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Des Moines
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Best
Last-minute
One-way
Cheapest flights from Charleston to Des MoinesExplore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mei 11, 2026.
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mei 11, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 5/277:47 pm
CHS
- DSM
1 stop5h 03m
American Airlines
di 6/25:00 am
DSM
- CHS
1 stop5h 31m
American Airlines
Deal found 5/6![American Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 5/218:20 pm
CHS
- DSM
1 stop24h 52m
Multiple Airlines
di 5/264:25 pm
DSM
- CHS
1 stop16h 13m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$361
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 7/12:10 pm
CHS
- DSM
2 stops9h 35m
Southwest
wo 7/85:20 am
DSM
- CHS
2 stops11h 55m
Southwest
Deal found 5/7![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/45:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
ma 6/84:40 pm
DSM
- CHS
1 stop5h 10m
Southwest
Deal found 5/6![Southwest logo]()
$375
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/115:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
di 6/163:45 pm
DSM
- CHS
1 stop4h 40m
Southwest
Deal found 5/6![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/46:03 pm
CHS
- DSM
1 stop5h 29m
Delta
di 6/96:39 pm
DSM
- CHS
1 stop4h 57m
Delta
Deal found 5/8![Delta logo]()
$385
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/56:06 am
CHS
- DSM
1 stop7h 51m
American Airlines
di 6/91:51 pm
DSM
- CHS
1 stop4h 39m
American Airlines
Deal found 5/9![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/66:41 am
CHS
- DSM
2 stops7h 36m
American Airlines
vr 6/127:10 am
DSM
- CHS
1 stop9h 29m
American Airlines
Deal found 5/7![American Airlines logo]()
$396
Best flights from Charleston to Des MoinesDiscover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mei 11, 2026.
Discover carefully curated flight deals from Charleston to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated mei 11, 2026.
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 5/277:47 pm
CHS
- DSM
1 stop5h 03m
American Airlines
di 6/25:00 am
DSM
- CHS
1 stop5h 31m
American Airlines
Deal found 5/6![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/45:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
ma 6/84:40 pm
DSM
- CHS
1 stop5h 10m
Southwest
Deal found 5/6![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/196:15 am
CHS
- DSM
1 stop5h 28m
Delta
di 6/232:25 pm
DSM
- CHS
1 stop5h 22m
Delta
Deal found 5/10![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 9/1012:05 pm
CHS
- DSM
2 stops11h 05m
Southwest
ma 9/143:50 pm
DSM
- CHS
1 stop4h 35m
Southwest
Deal found 5/9![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/65:20 am
CHS
- DSM
1 stop6h 54m
Delta
di 6/97:33 am
DSM
- CHS
1 stop9h 08m
Delta
Deal found 5/8![Delta logo]()
$385
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/115:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
di 6/163:45 pm
DSM
- CHS
1 stop4h 40m
Southwest
Deal found 5/6![Southwest logo]()
$381
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/54:55 pm
CHS
- DSM
1 stop6h 37m
Delta
wo 6/107:33 am
DSM
- CHS
1 stop6h 14m
Delta
Deal found 5/8![Delta logo]()
$411
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/194:45 pm
CHS
- DSM
2 stops7h 45m
Southwest
di 6/233:45 pm
DSM
- CHS
1 stop4h 40m
Southwest
Deal found 5/10![Southwest logo]()
$396
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/58:00 am
CHS
- DSM
1 stop4h 30m
Southwest
di 6/95:20 am
DSM
- CHS
2 stops9h 50m
Southwest
Deal found 5/8![Southwest logo]()
$406
Last-minute flights from Charleston to Des MoinesDiscover last-minute flight deals from Charleston to Des Moines. Data last updated mei 11, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Des Moines. Data last updated mei 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 5/218:20 pm
CHS
- DSM
1 stop24h 52m
Multiple Airlines
di 5/264:25 pm
DSM
- CHS
1 stop16h 13m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$361
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 5/277:47 pm
CHS
- DSM
1 stop5h 03m
American Airlines
di 6/25:00 am
DSM
- CHS
1 stop5h 31m
American Airlines
Deal found 5/6![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/45:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
ma 6/84:40 pm
DSM
- CHS
1 stop5h 10m
Southwest
Deal found 5/6![Southwest logo]()
$375
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/48:25 am
CHS
- DSM
1 stop6h 12m
Delta
ma 6/86:39 pm
DSM
- CHS
1 stop5h 06m
Delta
Deal found 5/8![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/46:15 am
CHS
- DSM
1 stop5h 53m
Delta
zo 6/76:38 pm
DSM
- CHS
1 stop4h 58m
Delta
Deal found 5/8![Delta logo]()
$401
This American Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/56:06 am
CHS
- DSM
1 stop7h 51m
American Airlines
di 6/91:51 pm
DSM
- CHS
1 stop4h 39m
American Airlines
Deal found 5/9![American Airlines logo]()
$391
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/66:41 am
CHS
- DSM
2 stops7h 36m
American Airlines
vr 6/127:10 am
DSM
- CHS
1 stop9h 29m
American Airlines
Deal found 5/7![American Airlines logo]()
$396
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/115:55 pm
CHS
- DSM
1 stop6h 35m
Southwest
di 6/163:45 pm
DSM
- CHS
1 stop4h 40m
Southwest
Deal found 5/6![Southwest logo]()
$381
One-way flights from Charleston to Des MoinesSearch for one-way flight options from Charleston to Des Moines. Find affordable one-way fares based on user searches. Data last updated mei 11, 2026.
Search for one-way flight options from Charleston to Des Moines. Find affordable one-way fares based on user searches. Data last updated mei 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 6/163:13 pm
CHS
- DSM
3 stops56h 45m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$167
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 6/166:45 pm
CHS
- DSM
1 stop5h 06m
United Airlines
Deal found 5/10![United Airlines logo]()
$178
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 6/1612:58 pm
CHS
- DSM
2 stops7h 37m
American Airlines
Deal found 5/10![American Airlines logo]()
$183
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 6/117:20 am
CHS
- DSM
1 stop4h 23m
Delta
Deal found 5/10![Delta logo]()
$188
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 6/101:50 pm
CHS
- DSM
2 stops9h 55m
Southwest
Deal found 5/6![Southwest logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/199:28 pm
CHS
- DSM
1 stop26h 24m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$197
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/276:00 am
CHS
- DSM
1 stop5h 49m
Delta
Deal found 5/6![Delta logo]()
$204
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 6/154:45 pm
CHS
- DSM
2 stops7h 45m
Southwest
Deal found 5/8![Southwest logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 6/108:56 pm
CHS
- DSM
3 stops27h 02m
Multiple Airlines
Deal found 5/6![Multiple Airlines logo]()
$216
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/194:45 pm
CHS
- DSM
2 stops7h 45m
Southwest
Deal found 5/8![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 6/121:55 pm
CHS
- DSM
2 stops10h 35m
Southwest
Deal found 5/8![Southwest logo]()
$229
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 6/2710:00 am
CHS
- DSM
2 stops10h 25m
United Airlines
Deal found 5/7![United Airlines logo]()
$249
Find flight deals from Charleston to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mei 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $355 (Southwest) |
One-way from | $167 (Kiwi.com) |
Popular in | November |
Cheapest in | April |
Average price | $320 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mei 11, 2026.
Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
wo 5/27
7:47 pm-11:50 pm
1 stop5h 03m
Des Moines
di 6/2
5:00 am-11:31 am
1 stop5h 31m
$355
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
do 6/4
5:55 pm-11:30 pm
1 stop6h 35m
Des Moines
ma 6/8
4:40 pm-10:50 pm
1 stop5h 10m
$375
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
do 9/10
12:05 pm-10:10 pm
2 stops11h 05m
Des Moines
ma 9/14
3:50 pm-9:25 pm
1 stop4h 35m
$380
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
vr 6/19
6:15 am-10:43 am
1 stop5h 28m
Des Moines
di 6/23
2:25 pm-8:47 pm
1 stop5h 22m
$381
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
do 6/11
5:55 pm-11:30 pm
1 stop6h 35m
Des Moines
di 6/16
3:45 pm-9:25 pm
1 stop4h 40m
$381
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
za 6/6
5:20 am-11:14 am
1 stop6h 54m
Des Moines
di 6/9
7:33 am-5:41 pm
1 stop9h 08m
$385
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
vr 6/19
4:45 pm-11:30 pm
2 stops7h 45m
Des Moines
di 6/23
3:45 pm-9:25 pm
1 stop4h 40m
$396
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
vr 6/5
8:00 am-11:30 am
1 stop4h 30m
Des Moines
di 6/9
5:20 am-4:10 pm
2 stops9h 50m
$406
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
vr 6/5
4:55 pm-10:32 pm
1 stop6h 37m
Des Moines
wo 6/10
7:33 am-2:47 pm
1 stop6h 14m
$411
Cheapest one-way
CharlestonDes Moines
CHS - DSM
CHSDSM
Charleston
di 6/16
3:13 pm-10:58 pm
3 stops56h 45m
$167
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Charleston to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charleston to Des Moines in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charleston-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charleston-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charleston-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charleston-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charleston-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charleston to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
CHS-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Des Moines
What is the cheapest month to book a flight from Charleston to Des Moines?
Currently, April is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $316). Flying from Charleston to Des Moines in November is currently the most expensive (average of $537). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Charleston to Des Moines?
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated mei 11, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Charleston to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.9
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ames
Clive
Boone
West Des Moines
Ankeny
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Other flights to Des Moines
Explore flights to Des Moines departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on mei 11, 2026.
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Charleston and Des Moines flights
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Top 2 airlines flying from Charleston to Des Moines
Discover the top 2 airlines that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mei 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$233 | Average$342 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$418 | FlexibilityNo cancel fee | On-timeN/A |