$98+ Cheap flights from Des Moines to Tampa (DSM - TPA)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — TPA
Oct 28 — Nov 41
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Tampa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Tampa
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to TampaExplore the most affordable flight options available from Des Moines to Tampa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from Des Moines to Tampa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This Frontier deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop27h 02m
Mon 11/26:15 am -
1 stop14h 20m
Deal found 9/25![Frontier logo]()
$178
This CheapOair deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:30 pm -
1 stop26h 57m
Thu 11/128:01 pm -
1 stop24h 34m
Deal found 9/25![Frontier logo]()
$233
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:25 am -
1 stop8h 06m
Mon 11/237:13 pm -
1 stop6h 13m
Deal found 9/23![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
2 stops5h 50m
Mon 11/25:35 am -
1 stop8h 35m
Deal found 9/26![Southwest logo]()
$238
This CheapOair deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:30 pm -
1 stop20h 04m
Mon 11/166:15 am -
1 stop14h 20m
Deal found 9/23![Frontier logo]()
$244
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:20 am -
2 stops10h 40m
Wed 12/166:50 am -
2 stops8h 25m
Deal found 9/23![Southwest logo]()
$247
This CheapOair deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:35 pm -
1 stop26h 02m
Sun 12/66:00 am -
1 stop14h 50m
Deal found 9/27![Frontier logo]()
$258
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/316:16 pm -
1 stop5h 01m
Thu 1/74:41 pm -
1 stop7h 59m
Deal found 9/27![American Airlines logo]()
$268
Best flights from Des Moines to TampaDiscover carefully curated flight deals from Des Moines to Tampa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from Des Moines to Tampa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:54 pm -
1 stop4h 24m
Wed 10/286:20 am -
1 stop5h 22m
Deal found 9/25![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
2 stops5h 50m
Mon 11/25:35 am -
1 stop8h 35m
Deal found 9/26![Southwest logo]()
$238
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/169:30 am -
2 stops8h 40m
Sun 12/204:36 pm -
1 stop5h 47m
Deal found 9/27![United Airlines logo]()
$342
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/171:50 pm -
2 stops9h 15m
Sun 12/207:55 am -
1 stop8h 10m
Deal found 9/27![Southwest logo]()
$372
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/195:15 am -
1 stop6h 00m
Mon 12/216:00 am -
1 stop6h 56m
Deal found 9/25![Delta logo]()
$447
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop6h 45m
Sun 12/62:00 pm -
2 stops8h 25m
Deal found 9/27![United Airlines logo]()
$452
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 am -
2 stops9h 02m
Mon 11/164:26 pm -
1 stop6h 29m
Deal found 9/27![United Airlines logo]()
$479
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
2 stops13h 09m
Sun 11/229:17 am -
2 stops12h 19m
Deal found 9/27![United Airlines logo]()
$510
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:00 am -
2 stops9h 02m
Mon 11/234:26 pm -
1 stop7h 33m
Deal found 9/25![United Airlines logo]()
$536
Last-minute flights from Des Moines to TampaDiscover last-minute flight deals from Des Moines to Tampa. Data last updated September 28, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Tampa. Data last updated September 28, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 pm -
1 stop20h 09m
Mon 10/266:15 am -
1 stop14h 15m
Deal found 9/27![Frontier logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/258:00 am -
2 stops50h 49m
Sun 11/17:16 am -
1 stop7h 43m
Deal found 9/25![Multiple Airlines logo]()
$300
This Frontier deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop27h 02m
Mon 11/26:15 am -
1 stop14h 20m
Deal found 9/25![Frontier logo]()
$178
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:27 pm -
1 stop8h 48m
Wed 10/2812:30 pm -
1 stop5h 57m
Deal found 9/25![United Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:10 am -
2 stops5h 50m
Mon 11/25:35 am -
1 stop8h 35m
Deal found 9/26![Southwest logo]()
$238
This CheapOair deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop26h 57m
Mon 11/26:15 am -
1 stop14h 20m
Deal found 9/23![Frontier logo]()
$244
One-way flights from Des Moines to TampaSearch for one-way flight options from Des Moines to Tampa. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from Des Moines to Tampa. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This Trip.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop27h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:25 am -
1 stop11h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Multiple Airlines logo]()
$99
This CheapOair deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:25 pm -
1 stop27h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Frontier logo]()
$100
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:27 am -
1 stop5h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:43 am -
1 stop23h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$121
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
2 stops8h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:37 pm -
1 stop11h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/26![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop25h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$138
Find flight deals from Des Moines to Tampa
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Tampa (TPA). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $178 (Frontier) |
One-way from | $98 (Trip.com) |
Popular in | December |
Cheapest in | February |
Average price | $391 |
Good round-trip deal | $234 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Tampa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from Des Moines to Tampa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Mon 10/19
8:25 pm-12:27 am
1 stop27h 02m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$98
Quickest round-trip
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Wed 10/21
5:35 am-11:25 am
1 stop4h 50m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Sat 10/24
8:00 am-4:48 pm
1 stop7h 48m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Tue 10/20
3:03 pm-9:24 pm
1 stop5h 21m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Tue 12/1
4:53 pm-12:01 am
1 stop6h 08m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Wed 11/4
4:07 pm-12:18 am
1 stop7h 11m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$119
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Fri 10/23
8:25 pm-5:34 pm
1 stop20h 09m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$155
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Wed 10/14
6:00 am-3:16 pm
2 stops8h 16m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$190
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Fri 10/23
10:00 pm-10:54 pm
3 stops23h 54m
Tampa
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$195
Des MoinesTampa
DSM Des Moines - TPA Tampa
DSMTPA
Des Moines
Mon 10/26
6:54 pm-12:18 am
1 stop4h 24m
Tampa
Wed 10/28
6:20 am-10:42 am
1 stop5h 22m
$237
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Tampa
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Tampa in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Des Moines-Tampa flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Tampa flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Tampa flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Tampa flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Tampa flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Tampa
Have a flexible travel schedule? Discover the best time to fly to Tampa from Des Moines with our price prediction graph.
DSM-TPA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Tampa
How far ahead should I book a flight from Des Moines to Tampa?
To ensure you get the cheapest price possible for a flight from Des Moines to Tampa, you should look to book at least 66 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Des Moines to Tampa?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Tampa (average of $347). Flying from Des Moines to Tampa in December is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Tampa?
Airfare is below average for this route at the moment.
Des Moines to Tampa flights typically cost between $332 and $586 in October.The cheapest round-trip price found within the last 5 days was $178 on Frontier (Oct 26-Nov 2).
Reviews of airlines servicing Tampa
Get insights into the airlines that provide service to Tampa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tampa. Reviews last updated September 28, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to Tampa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Tampa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Tampa?
Book flights to Tampa if you plan to visit one of these locationsSt. Petersburg
Saint Pete Beach
Lakewood Ranch
Tarpon Springs
Brandon
Spring Hill
Indian Rocks Beach
Seminole
Treasure Island
Ruskin
Zephyrhills
Largo
Safety Harbor
Dunedin
Anna Maria
Pinellas Park
Crystal River
Plant City
Holmes Beach
Madeira Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Des Moines
Popular flights
Tampa flight routes
Alternative routes for Des Moines to Tampa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Tampa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Tampa by cabin class
Find flights from Des Moines to Tampa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Tampa flights
Browse other Des Moines and Tampa flight options. Last updated on September 28, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Tampa
Explore flights to Tampa departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Top 6 airlines flying from Des Moines to Tampa
Discover the top 6 airlines that operate flights from Des Moines to Tampa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$73 | Average$330 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$162 | Average$254 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$236 | Average$387 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$436 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$293 | Average$492 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$296 | Average$397 | FlexibilityNo cancel fee | On-time69% |