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St. Louis

$95+ Cheap flights from South Carolina to St. Louis (STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STL
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from South Carolina to St. Louis

Keep the following information in mind while searching for South Carolina to St. Louis flight deals. Data was last updated April 30, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$171
(CheapOair)

One-way from

$95
(Frontier)

Popular in

April

Cheapest in

July

Average price

$432

Good round-trip deal

$400 or less

Good one-way deal

$164 or less
Provider with most accurate pricing for Myrtle Beach Intl-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Lambert-St Louis flights.
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From South Carolina to Lambert-St Louis
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One-way flight from South Carolina to Lambert-St Louis
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Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Price to beat on a round-trip flight from South Carolina to Lambert-St Louis.
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Price to beat on a one-way flight from South Carolina to Lambert-St Louis.
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Find flight deals from South Carolina to St. Louis

Cheapest flights from South Carolina to St. Louis
Explore the most affordable flight options available from South Carolina to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1510:36 pmCLT - STL
1 stop26h 38mFrontier
Wed 5/215:45 pmSTL - CLT
1 stop15h 56mFrontier
Deal found 4/28$171
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/317:25 amCAE - STL
1 stop5h 27mAmerican Airlines
Sat 6/75:37 amSTL - CAE
1 stop8h 10mAmerican Airlines
Deal found 4/29$211
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/285:55 pmCAE - STL
1 stop3h 44mDelta
Tue 6/109:28 amSTL - CAE
1 stop3h 47mDelta
Deal found 4/29$217
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/233:14 pmCLT - STL
1 stop9h 38mMultiple Airlines
Sun 5/2510:10 amSTL - CLT
1 stop8h 47mMultiple Airlines
Deal found 4/29$219
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/268:30 pmCHS - STL
1 stop4h 29mAmerican Airlines
Fri 7/46:00 amSTL - CHS
1 stop6h 56mAmerican Airlines
Deal found 4/29$227
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1810:35 amCLT - STL
Nonstop2h 00mSouthwest
Tue 6/242:00 pmSTL - CLT
Nonstop1h 50mSouthwest
Deal found 4/28$255
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/248:30 pmCLT - STL
Nonstop1h 56mAmerican Airlines
Sun 5/255:12 amSTL - CLT
Nonstop1h 58mAmerican Airlines
Deal found 4/29$256
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:00 pmGSP - STL
1 stop6h 38mDelta
Sun 5/2510:05 amSTL - GSP
1 stop5h 18mDelta
Deal found 4/28$257
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/256:00 amAGS - STL
1 stop3h 56mAmerican Airlines
Sat 5/316:47 pmSTL - AGS
1 stop4h 02mAmerican Airlines
Deal found 4/28$271
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/248:20 amCLT - STL
1 stop4h 34mDelta
Sun 5/2510:45 amSTL - CLT
1 stop4h 08mDelta
Deal found 4/29$275
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/216:35 amCLT - STL
1 stop6h 44mUnited Airlines
Tue 10/213:30 pmSTL - CLT
2 stops7h 29mUnited Airlines
Deal found 4/28$280
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/95:00 pmCHS - STL
Nonstop2h 10mSouthwest
Wed 6/1112:15 pmSTL - CHS
1 stop4h 50mSouthwest
Deal found 4/29$281

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from South Carolina to St. Louis that are best for you.

Fly from

South Carolina

Fly to

St. Louis

Route

Depart

Return

Price

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Thu 5/15

10:36 pm-12:14 am

1 stop26h 38m

Lambert-St Louis

Wed 5/21

5:45 pm-10:41 am

1 stop15h 56m

$171

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Sat 5/31

7:25 am-11:52 am

1 stop5h 27m

Lambert-St Louis

Sat 6/7

5:37 am-2:47 pm

1 stop8h 10m

$211

ColumbiaSt. Louis

CAE - STL

CAESTL

Columbia Metropolitan

Wed 5/28

5:55 pm-8:39 pm

1 stop3h 44m

Lambert-St Louis

Tue 6/10

9:28 am-2:15 pm

1 stop3h 47m

$217

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Fri 5/23

3:14 pm-11:52 pm

1 stop9h 38m

Lambert-St Louis

Sun 5/25

10:10 am-7:57 pm

1 stop8h 47m

$219

CharlestonSt. Louis

CHS - STL

CHSSTL

Charleston

Thu 6/26

8:30 pm-11:59 pm

1 stop4h 29m

Lambert-St Louis

Fri 7/4

6:00 am-1:56 pm

1 stop6h 56m

$227

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Wed 6/18

10:35 am-11:35 am

Nonstop2h 00m

Lambert-St Louis

Tue 6/24

2:00 pm-4:50 pm

Nonstop1h 50m

$255

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 5/24

8:30 pm-9:26 pm

Nonstop1h 56m

Lambert-St Louis

Sun 5/25

5:12 am-8:10 am

Nonstop1h 58m

$256

GreenvilleSt. Louis

GSP - STL

GSPSTL

Greenville

Tue 5/20

6:00 pm-11:38 pm

1 stop6h 38m

Lambert-St Louis

Sun 5/25

10:05 am-4:23 pm

1 stop5h 18m

$257

AugustaSt. Louis

AGS - STL

AGSSTL

Augusta Bush Field

Sun 5/25

6:00 am-8:56 am

1 stop3h 56m

Lambert-St Louis

Sat 5/31

6:47 pm-11:49 pm

1 stop4h 02m

$271

CharlotteSt. Louis

CLT - STL

CLTSTL

Charlotte Douglas

Sat 5/24

8:20 am-11:54 am

1 stop4h 34m

Lambert-St Louis

Sun 5/25

10:45 am-3:53 pm

1 stop4h 08m

$275

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 57 results
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Best time to book a flight from South Carolina to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to St. Louis

What is the cheapest month to book a flight from South Carolina to St. Louis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to STL?

Find hourly flight availability from South Carolina to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

When flying from South Carolina to St. Louis, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in St. Louis by month

Plan your trip to St. Louis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

Temperature in St. Louis by month

Plan your trip to St. Louis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 30, 2025.
Read through reviews of airlines operating flights from South Carolina to St. Louis, such as Alaska Airlines, Southwest and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,961 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,295 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,929 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.1

Overall

8.0

Food

7.1

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to St. Louis from South Carolina?

    For a flight from South Carolina to St. Louis, you will be flying into Lambert-St Louis. Lambert-St Louis (STL) is just 12.7 mi from the center of the city.

  • How popular is this South Carolina to St. Louis flight route?

    Within the past month, 3 users have taken a look at flights from South Carolina to Lambert-St Louis.

  • What are the cheapest airlines to fly from South Carolina to St. Louis one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $95. American Airlines flights start at $95 while deals on Spirit Airlines start at $97 one-way.

  • What are the most popular routes from South Carolina to St. Louis?

    The most popular flight routes from South Carolina to St. Louis are Charlotte Douglas - Lambert-St Louis, Charleston - Lambert-St Louis and Savannah/Hilton Head - Lambert-St Louis.

  • What are the cheapest flights from South Carolina to St. Louis?

    On average you can expect to pay $374 for a flight from South Carolina to St. Louis. The cheapest flight overall is $143 while the most popular route, (Charlotte Douglas - Lambert-St Louis) is currently priced at $242.

  • Can I find deals for flights from South Carolina to St. Louis that include hotel bookings?

    Yes. In addition to deals on South Carolina to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to St. Louis.

  • Can I find deals for business class flights from South Carolina to St. Louis?

    Yes. Cheapflights offers flight deals from South Carolina to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to St. Louis (average of $311). Flying from South Carolina to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Fenton
Maryland Heights
Fairview Heights
Collinsville
Wentzville
Eureka
St. Peters
Festus
Glencoe
Alton
Farmington
O'Fallon

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Alternative routes for South Carolina to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from South Carolina to St. Louis

Discover the top 4 airlines that operate flights from South Carolina to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$149Average$201FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$172Average$356FlexibilityNo cancel feeOn-time71%
DeltaCheapest$238Average$362FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$286Average$364FlexibilityNo cancel feeOn-time63%

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