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South Carolina

$240+ Cheap flights from Panama City (PTY) to South Carolina

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Panama City to South Carolina

Keep the following information in mind while searching for Panama City to South Carolina flight deals. Data was last updated June 12, 2025.

Round-trip from

$415
(Delta)

One-way from

$240
(Delta)
From Panama City Tocumen Intl to South Carolina
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One-way flight from Panama City Tocumen Intl to South Carolina
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Find flight deals from Panama City to South Carolina

Cheapest flights from Panama City to South Carolina
Explore the most affordable flight options available from Panama City to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/278:10 amPTY - CHS
1 stop9h 44mDelta
Sun 8/35:15 amCHS - PTY
1 stop8h 58mDelta
Deal found 6/12$415
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/271:55 pmPTY - CHS
2 stops19h 23mAmerican Airlines
Sun 8/36:13 pmCHS - PTY
2 stops19h 41mAmerican Airlines
Deal found 6/12$428
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/110:00 amPTY - CHS
1 stop11h 45mUnited Airlines
Sat 7/267:00 amCHS - PTY
1 stop10h 12mUnited Airlines
Deal found 6/9$468
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:17 pmPTY - CLT
1 stop8h 37mDelta
Tue 1/137:40 amCLT - PTY
1 stop6h 22mDelta
Deal found 6/10$470
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/712:48 pmPTY - CLT
1 stop6h 59mMultiple Airlines
Sat 8/165:55 pmCLT - PTY
1 stop15h 16mMultiple Airlines
Deal found 6/10$483
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1610:00 amPTY - CLT
1 stop10h 57mUnited Airlines
Thu 9/257:00 amCLT - PTY
1 stop8h 14mUnited Airlines
Deal found 6/10$490
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:20 pmPTY - CAE
2 stops20h 13mAmerican Airlines
Tue 12/26:29 pmCAE - PTY
2 stops20h 56mAmerican Airlines
Deal found 6/11$495
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/171:50 pmPTY - CLT
1 stop21h 27mAmerican Airlines
Mon 10/202:37 pmCLT - PTY
1 stop22h 48mAmerican Airlines
Deal found 6/11$501
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/153:20 amPTY - CAE
3 stops33h 58mMultiple Airlines
Sun 7/209:50 pmCAE - PTY
3 stops27h 55mMultiple Airlines
Deal found 6/9$553
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/203:25 amPTY - CHS
3 stops28h 12mMultiple Airlines
Sat 7/129:48 pmCHS - PTY
3 stops24h 22mMultiple Airlines
Deal found 6/12$636
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/210:55 pmPTY - MYR
1 stop10h 02mUnited Airlines
Wed 7/910:53 amMYR - PTY
1 stop9h 38mUnited Airlines
Deal found 6/11$642
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/263:10 pmPTY - AGS
2 stops22h 03mAmerican Airlines
Sat 8/26:08 pmAGS - PTY
2 stops21h 07mAmerican Airlines
Deal found 6/11$674

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Panama City to South Carolina that are best for you.

Fly from

Panama City

Fly to

South Carolina

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 7/27

8:10 am-6:54 pm

1 stop9h 44m

Charleston

Sun 8/3

5:15 am-1:13 pm

1 stop8h 58m

$415

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 7/27

1:55 pm-10:18 am

2 stops19h 23m

Charleston

Sun 8/3

6:13 pm-12:54 pm

2 stops19h 41m

$428

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 7/1

10:00 am-10:45 pm

1 stop11h 45m

Charleston

Sat 7/26

7:00 am-4:12 pm

1 stop10h 12m

$468

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Wed 8/6

2:28 pm-11:58 pm

1 stop8h 30m

Charlotte Douglas

Mon 8/11

5:00 pm-12:50 pm

1 stop20h 50m

$481

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Thu 8/7

12:48 pm-8:47 pm

1 stop6h 59m

Charlotte Douglas

Sat 8/16

5:55 pm-8:11 am

1 stop15h 16m

$483

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Fri 7/25

1:55 pm-7:26 am

1 stop16h 31m

Charlotte Douglas

Fri 8/1

5:17 am-12:54 pm

1 stop8h 37m

$512

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Fri 7/25

1:55 pm-2:06 pm

2 stops23h 11m

Columbia Metropolitan

Fri 8/1

7:45 pm-2:15 pm

2 stops19h 30m

$538

Panama CityCharlotte

PTY - CLT

PTYCLT

Panama City Tocumen Intl

Tue 8/5

10:55 pm-10:20 am

1 stop10h 25m

Charlotte Douglas

Fri 8/15

7:00 am-6:37 pm

1 stop12h 37m

$545

Panama CityColumbia

PTY - CAE

PTYCAE

Panama City Tocumen Intl

Tue 7/15

3:20 am-2:18 pm

3 stops33h 58m

Columbia Metropolitan

Sun 7/20

9:50 pm-12:45 am

3 stops27h 55m

$553

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 6/20

3:25 am-8:37 am

3 stops28h 12m

Charleston

Sat 7/12

9:48 pm-9:10 pm

3 stops24h 22m

$636

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 33 results
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Best time to book a flight from Panama City to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to South Carolina

What is the cheapest time of day to fly from PTY to SC?

Find hourly flight availability from Panama City to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to South Carolina as you normally would.

Rainfall in South Carolina by month

Plan your trip to South Carolina by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

Temperature in South Carolina by month

Plan your trip to South Carolina by taking into account the average temperature totals by month.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines and United Airlines from Panama City to South Carolina. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,946 reviews

Overall

8.0

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Panama City to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to South Carolina?

    Panama City Tocumen Intl (PTY) is the airport you will fly out of if you book a flight from Panama City to South Carolina. It is only a 11.4 mi journey to Tocumen Intl (PTY) from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City to South Carolina one-way?

    The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $240. However, be on the lookout for offers from American Airlines and United Airlines, as they are both options that can get you from Panama City to South Carolina for a low price.

  • What are the most popular routes from Panama City to South Carolina?

    The most popular flight routes from Panama City to South Carolina are Panama City Tocumen Intl - Charlotte Douglas, Panama City Tocumen Intl - Charleston and Panama City Tocumen Intl - Columbia Metropolitan.

  • Can I find deals for flights from Panama City to South Carolina that include hotel bookings?

    Yes. In addition to deals on Panama City to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to South Carolina.

  • Can I find deals for business class flights from Panama City to South Carolina?

    Yes. Cheapflights offers flight deals from Panama City to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to South Carolina?

    Currently, August is the cheapest month in which you can book a flight from Panama City to South Carolina (average of $217). Flying from Panama City to South Carolina in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to South Carolina

Discover the top airline that operate flights from Panama City to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$423Average$501FlexibilityNo cancel feeOn-time71%

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