$93+ Cheap flights from the United States to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/20. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Apr 2 — Apr 91
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from USA to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from USA to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from USA to South AmericaExplore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Sat 3/211:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$198
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 pm
FLL
- MDE
1 stop16h 36m
Spirit Airlines
Thu 4/92:17 pm
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$202
This Cheapflightsfares deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:45 am
FLL
- MDE
Nonstop3h 23m
Spirit Airlines
Sun 4/191:11 am
MDE
- FLL
Nonstop3h 29m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$205
This Cheapflightsfares deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:01 pm
FLL
- MDE
Nonstop3h 15m
Spirit Airlines
Tue 5/1910:51 am
MDE
- FLL
1 stop8h 08m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$208
This CheapOair deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:45 am
FLL
- MDE
Nonstop3h 28m
Spirit Airlines
Sat 3/73:15 pm
MDE
- FLL
Nonstop3h 35m
Spirit Airlines
Deal found 3/1![Spirit Airlines logo]()
$214
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:45 am
FLL
- MDE
Nonstop3h 28m
Spirit Airlines
Mon 3/161:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$217
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Mon 3/301:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$220
This Priceline deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Fri 3/201:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$221
This Cheapflightsfares deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Wed 4/12:17 pm
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/3![Spirit Airlines logo]()
$225
This CheapOair deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:00 am
FLL
- MDE
Nonstop3h 22m
Spirit Airlines
Sun 3/291:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/3![Spirit Airlines logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:45 am
FLL
- MDE
Nonstop3h 23m
Spirit Airlines
Sun 4/192:06 pm
MDE
- FLL
Nonstop3h 44m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$228
This eDestinos deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:09 pm
MIA
- MDE
1 stop6h 31m
Arajet
Thu 4/1610:05 am
MDE
- MIA
1 stop8h 17m
Arajet
Deal found 3/1![Arajet logo]()
$238
Best flights from USA to South AmericaDiscover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
Discover carefully curated flight deals from USA to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
This Spirit deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/310:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Mon 4/61:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$239
This Copa Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:00 am
MIA
- MDE
1 stop5h 55m
Copa Airlines
Sun 4/125:00 am
MDE
- MIA
1 stop8h 42m
Copa Airlines
Deal found 2/27![Copa Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:10 pm
FLL
- MDE
1 stop9h 00m
United Airlines
Thu 4/169:45 am
MDE
- FLL
1 stop11h 41m
United Airlines
Deal found 2/28![United Airlines logo]()
$317
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:45 am
MIA
- LIM
Nonstop5h 45m
Delta
Mon 4/138:15 am
LIM
- MIA
Nonstop6h 05m
Delta
Deal found 3/3![Delta logo]()
$325
This JetBlue deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:25 am
JFK
- GYE
Nonstop6h 33m
JetBlue
Fri 4/2412:25 pm
GYE
- JFK
1 stop19h 34m
JetBlue
Deal found 3/2![JetBlue logo]()
$380
This Spirit deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Tue 4/71:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$249
This Copa Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:01 am
MIA
- MDE
1 stop5h 55m
Copa Airlines
Fri 4/106:25 am
MDE
- MIA
1 stop7h 17m
Copa Airlines
Deal found 2/27![Copa Airlines logo]()
$265
This Copa Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:24 am
MIA
- MDE
1 stop5h 31m
Copa Airlines
Tue 4/213:10 pm
MDE
- MIA
1 stop6h 13m
Copa Airlines
Deal found 2/28![Copa Airlines logo]()
$265
This Spirit deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 pm
FLL
- MDE
1 stop16h 36m
Spirit Airlines
Sun 4/51:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/28![Spirit Airlines logo]()
$281
This Copa Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:24 am
MIA
- MDE
1 stop8h 51m
Copa Airlines
Wed 4/155:00 am
MDE
- MIA
1 stop8h 42m
Copa Airlines
Deal found 3/1![Copa Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:40 am
FLL
- MDE
1 stop13h 30m
United Airlines
Sun 4/269:45 am
MDE
- FLL
3 stops25h 16m
United Airlines
Deal found 3/1![United Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:05 am
JFK
- BOG
1 stop10h 40m
Delta
Tue 3/246:15 am
BOG
- JFK
2 stops17h 30m
Delta
Deal found 3/1![Delta logo]()
$325
This Copa Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:28 am
MIA
- MDE
1 stop15h 22m
Copa Airlines
Sun 4/195:00 am
MDE
- MIA
1 stop6h 27m
Copa Airlines
Deal found 3/1![Copa Airlines logo]()
$265
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/67:40 pm
MIA
- MDE
2 stops26h 30m
United Airlines
Mon 5/119:45 am
MDE
- MIA
2 stops28h 12m
United Airlines
Deal found 2/28![United Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/187:05 am
JFK
- BOG
1 stop10h 40m
Delta
Wed 4/1511:00 am
BOG
- JFK
2 stops12h 48m
Delta
Deal found 3/2![Delta logo]()
$330
This Copa Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:01 am
MIA
- MDE
1 stop9h 14m
Copa Airlines
Mon 3/910:46 am
MDE
- MIA
1 stop10h 38m
Copa Airlines
Deal found 2/26![Copa Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/141:10 pm
JFK
- BOG
1 stop8h 10m
Delta
Wed 3/187:00 am
BOG
- JFK
2 stops13h 29m
Delta
Deal found 2/26![Delta logo]()
$330
This JetBlue deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:25 am
JFK
- GYE
Nonstop6h 33m
JetBlue
Sat 5/234:15 pm
GYE
- JFK
Nonstop6h 31m
JetBlue
Deal found 2/28![JetBlue logo]()
$405
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:40 am
FLL
- MDE
1 stop13h 30m
United Airlines
Thu 5/149:45 am
MDE
- FLL
2 stops36h 04m
United Airlines
Deal found 2/26![United Airlines logo]()
$335
This Copa Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:28 am
MIA
- MDE
1 stop6h 47m
Copa Airlines
Sun 4/1912:40 pm
MDE
- MIA
1 stop12h 01m
Copa Airlines
Deal found 2/28![Copa Airlines logo]()
$265
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
JFK
- BOG
2 stops15h 20m
Delta
Tue 3/246:15 am
BOG
- JFK
2 stops17h 30m
Delta
Deal found 3/1![Delta logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:15 pm
FLL
- MDE
2 stops33h 55m
United Airlines
Sun 5/109:45 am
MDE
- FLL
2 stops24h 34m
United Airlines
Deal found 3/1![United Airlines logo]()
$335
This JetBlue deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:50 am
JFK
- GYE
1 stop8h 50m
JetBlue
Thu 4/2312:25 pm
GYE
- JFK
1 stop10h 56m
JetBlue
Deal found 2/27![JetBlue logo]()
$408
This Copa Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:28 am
MIA
- MDE
1 stop6h 47m
Copa Airlines
Fri 5/112:40 pm
MDE
- MIA
1 stop9h 02m
Copa Airlines
Deal found 2/27![Copa Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:10 pm
JFK
- BOG
1 stop8h 00m
Delta
Thu 4/169:00 am
BOG
- JFK
1 stop12h 30m
Delta
Deal found 3/2![Delta logo]()
$334
This JetBlue deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:01 am
JFK
- GYE
Nonstop6h 33m
JetBlue
Wed 4/2212:25 pm
GYE
- JFK
1 stop10h 30m
JetBlue
Deal found 2/26![JetBlue logo]()
$425
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:17 pm
FLL
- MDE
2 stops29h 53m
United Airlines
Mon 5/49:45 am
MDE
- FLL
2 stops28h 07m
United Airlines
Deal found 3/2![United Airlines logo]()
$357
This Copa Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:24 am
MIA
- MDE
1 stop8h 51m
Copa Airlines
Mon 5/410:35 am
MDE
- MIA
1 stop8h 23m
Copa Airlines
Deal found 3/2![Copa Airlines logo]()
$275
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/201:10 pm
JFK
- BOG
1 stop8h 10m
Delta
Tue 3/246:15 am
BOG
- JFK
2 stops17h 30m
Delta
Deal found 3/3![Delta logo]()
$345
This JetBlue deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/55:01 am
JFK
- GYE
Nonstop6h 33m
JetBlue
Wed 4/2212:25 pm
GYE
- JFK
1 stop10h 30m
JetBlue
Deal found 3/1![JetBlue logo]()
$425
Last-minute flights from USA to South AmericaDiscover last-minute flight deals from USA to South America. Data last updated March 3, 2026 and is based on user searches.
Discover last-minute flight deals from USA to South America. Data last updated March 3, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:45 am
FLL
- MDE
Nonstop3h 28m
Spirit Airlines
Sat 3/73:15 pm
MDE
- FLL
Nonstop3h 35m
Spirit Airlines
Deal found 3/1![Spirit Airlines logo]()
$214
This Mytrip deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:45 am
FLL
- MDE
Nonstop3h 28m
Spirit Airlines
Mon 3/161:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$217
This Priceline deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Fri 3/201:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$221
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Sat 3/211:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$198
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Mon 3/301:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$220
This Cheapflightsfares deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Wed 4/12:17 pm
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/3![Spirit Airlines logo]()
$225
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Tue 3/241:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$230
This CheapOair deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2111:00 am
FLL
- MDE
Nonstop3h 22m
Spirit Airlines
Sun 3/291:17 am
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/3![Spirit Airlines logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:15 pm
FLL
- MDE
1 stop16h 36m
Spirit Airlines
Thu 4/92:17 pm
MDE
- FLL
Nonstop3h 33m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$202
This eDestinos deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:09 pm
MIA
- MDE
1 stop6h 31m
Arajet
Thu 4/1610:05 am
MDE
- MIA
1 stop8h 17m
Arajet
Deal found 3/1![Arajet logo]()
$238
This Cheapflightsfares deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:45 am
FLL
- MDE
Nonstop3h 23m
Spirit Airlines
Sun 4/191:11 am
MDE
- FLL
Nonstop3h 29m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$205
This Cheapflightsfares deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:45 am
FLL
- MDE
Nonstop3h 23m
Spirit Airlines
Sun 4/192:06 pm
MDE
- FLL
Nonstop3h 44m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$228
One-way flights from USA to South AmericaSearch for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
Search for one-way flight options from USA to South America. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:21 am
FLL
- MDE
1 stop23h 09m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:21 am
FLL
- MDE
1 stop23h 09m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$94
This Super.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:21 am
FLL
- MDE
1 stop23h 45m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$96
This Spirit deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2810:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2910:21 am
FLL
- MDE
1 stop16h 00m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2610:25 am
FLL
- MDE
1 stop15h 53m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$101
This Spirit deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:05 pm
FLL
- MDE
Nonstop3h 16m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$102
This eDestinos deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:09 pm
MIA
- MDE
1 stop6h 31m
Arajet
Deal found 2/27![Arajet logo]()
$102
This Mytrip deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:21 am
FLL
- MDE
1 stop12h 32m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$103
This Jetabroad deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:21 am
FLL
- MDE
1 stop22h 44m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$105
This Jetabroad deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Jetabroad is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:21 am
FLL
- MDE
1 stop23h 09m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$106
Find flight deals from USA to South America
Keep the following information in mind while searching for USA to South America flight deals. Data was last updated March 3, 2026.
Round-trip from | $198 (Cheapflightsfares) |
|---|---|
One-way from | $93 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $526 |
Good round-trip deal | $187 or less |
Good one-way deal | $68 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Fort LauderdaleMedellín
FLL - MDE
FLLMDE
Fort Lauderdale
Fri 4/3
10:05 pm-12:21 am
Nonstop3h 16m
Medellín Jose Maria Cordova Intl
Mon 4/6
1:17 am-5:50 am
Nonstop3h 33m
$239
Fort LauderdaleMedellín
FLL - MDE
FLLMDE
Fort Lauderdale
Wed 4/1
10:05 pm-12:21 am
Nonstop3h 16m
Medellín Jose Maria Cordova Intl
Tue 4/7
1:17 am-5:50 am
Nonstop3h 33m
$249
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Thu 4/9
6:00 am-10:55 am
1 stop5h 55m
Medellín Jose Maria Cordova Intl
Sun 4/12
5:00 am-2:42 pm
1 stop8h 42m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Mon 3/23
6:01 am-10:56 am
1 stop5h 55m
Medellín Jose Maria Cordova Intl
Fri 4/10
6:25 am-2:42 pm
1 stop7h 17m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Fri 4/17
6:24 am-10:55 am
1 stop5h 31m
Medellín Jose Maria Cordova Intl
Tue 4/21
3:10 pm-10:23 pm
1 stop6h 13m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Sat 4/11
6:24 am-2:15 pm
1 stop8h 51m
Medellín Jose Maria Cordova Intl
Wed 4/15
5:00 am-2:42 pm
1 stop8h 42m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Thu 4/16
8:28 am-10:50 pm
1 stop15h 22m
Medellín Jose Maria Cordova Intl
Sun 4/19
5:00 am-12:27 pm
1 stop6h 27m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Fri 3/6
5:01 am-2:15 pm
1 stop9h 14m
Medellín Jose Maria Cordova Intl
Mon 3/9
10:46 am-10:24 pm
1 stop10h 38m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Fri 4/17
8:28 am-2:15 pm
1 stop6h 47m
Medellín Jose Maria Cordova Intl
Sun 4/19
12:40 pm-1:41 am
1 stop12h 01m
$265
MiamiMedellín
MIA - MDE
MIAMDE
Miami
Tue 4/28
8:28 am-2:15 pm
1 stop6h 47m
Medellín Jose Maria Cordova Intl
Fri 5/1
12:40 pm-10:42 pm
1 stop9h 02m
$275
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to South America
Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
FLL-MDE
MIA-MDE
MIA-LIM
JFK-GYE
JFK-BOG
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to South America
US0-0SA
FLL-MDE
MIA-MDE
MIA-LIM
JFK-GYE
What is the cheapest month to book a flight from USA to South America?
Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $78). Flying from USA to South America in December is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SA?
Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 3, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from USA to South America by exploring options for tickets in the morning.
What is the cheapest day to fly from USA to South America?
Use this chart to determine the cheapest time to fly round-trip from USA to South America. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their USA to South America flight should consider departing on Saturday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 3, 2026.
Get a feel of what it's like to fly with Delta, Copa Airlines, and LATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top countries
Top destinations
Alternative routes for USA to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to South America by cabin class
Find flights from USA to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and South America flights
Browse other USA and South America flight options. Last updated on March 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South America
Find the right flight back to USA after your stay in South America
Fly to South America countries
Consider these flights traveling to countries located in South America.
USA to South America flights
Consider these flights traveling from USA to South America.
Top 10 airlines flying from USA to South America
Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$127 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$101 | Average$388 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$106 | Average$457 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$117 | Average$805 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$126 | Average$579 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$143 | Average$209 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$150 | Average$749 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$154 | Average$530 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$154 | Average$655 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$162 | Average$756 | FlexibilityNo cancel fee | On-time81% |