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South America

$98+ Cheap flights from the United States to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/21. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
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Cheap flight deals from USA to South America

Cheapest flights from USA to South America
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This Priceline deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:50 am
FLL
-
MDE
1 stop7h 02m
Spirit Airlines
Mon 4/131:52 pm
MDE
-
FLL
1 stop16h 14m
Spirit Airlines
Deal found 3/12$224
This eDestinos deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Tue 3/171:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/11$226
This Cheapflightsfares deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2211:00 am
FLL
-
MDE
Nonstop3h 22m
Spirit Airlines
Mon 3/301:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/9$228
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Mon 3/301:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/8$229
This Cheapflightsfares deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2810:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Fri 4/31:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/10$230
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:00 am
FLL
-
MDE
Nonstop3h 22m
Spirit Airlines
Mon 4/61:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/12$231
This Mytrip deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Wed 4/82:17 pm
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/12$232
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2911:00 am
FLL
-
MDE
Nonstop3h 22m
Spirit Airlines
Mon 4/61:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/9$238
This Cheapflightsfares deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2810:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Wed 4/11:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/9$240
This Spirit deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Wed 3/182:17 pm
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/9$241
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2910:05 pm
FLL
-
MDE
Nonstop3h 16m
Spirit Airlines
Sun 4/51:17 am
MDE
-
FLL
Nonstop3h 33m
Spirit Airlines
Deal found 3/9$242
This eDestinos deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/202:09 pm
MIA
-
MDE
1 stop6h 31m
Arajet
Sat 4/2510:05 am
MDE
-
MIA
1 stop6h 50m
Arajet
Deal found 3/11$248

Find flight deals from USA to South America

Keep the following information in mind while searching for USA to South America flight deals. Data was last updated March 14, 2026.

Round-trip from

$224
(Priceline)

One-way from

$98
(Cheapflightsfares)

Popular in

December

Cheapest in

September

Average price

$488

Good round-trip deal

$189 or less

Good one-way deal

$90 or less
From USA to South America
Search Deals
One-way flight from USA to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from USA to South America.
Search Deals
Price to beat on a one-way flight from USA to South America.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from the United States to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Wed 4/1

10:05 pm-12:21 am

Nonstop3h 16m

Medellín Jose Maria Cordova Intl

Tue 4/7

1:17 am-5:50 am

Nonstop3h 33m

$258

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 5/8

7:50 pm-10:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

Sun 5/10

11:50 pm-4:20 am

Nonstop3h 30m

$283

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Mon 3/23

6:11 pm-8:18 am

1 stop15h 07m

Medellín Jose Maria Cordova Intl

Tue 3/31

5:00 am-4:17 pm

1 stop10h 17m

$285

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Wed 4/8

6:14 pm-9:40 am

1 stop16h 26m

Medellín Jose Maria Cordova Intl

Wed 4/15

9:15 am-4:16 pm

1 stop6h 01m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 4/17

6:24 am-2:15 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Tue 4/21

5:00 am-2:42 pm

1 stop8h 42m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 4/14

6:24 am-2:15 pm

1 stop8h 51m

Medellín Jose Maria Cordova Intl

Thu 4/16

6:20 pm-1:41 am

1 stop6h 21m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 5/7

5:14 pm-8:15 am

1 stop16h 01m

Medellín Jose Maria Cordova Intl

Sun 5/10

12:40 pm-7:58 pm

1 stop6h 18m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 4/21

8:28 am-2:45 pm

1 stop7h 17m

Medellín Jose Maria Cordova Intl

Thu 4/23

6:20 pm-1:41 am

1 stop6h 21m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 4/23

5:14 pm-10:50 pm

1 stop6h 36m

Medellín Jose Maria Cordova Intl

Tue 4/28

4:30 pm-1:41 am

1 stop8h 11m

$285

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Wed 3/25

6:01 am-10:56 am

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Mon 4/13

5:00 am-2:42 pm

1 stop8h 42m

$285

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from USA to South America

Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to South America

What is the cheapest month to book a flight from USA to South America?

Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $78). Flying from USA to South America in December is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to SA?

Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 14, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 22% on flights from USA to South America by exploring options for tickets in the morning.

What is the cheapest day to fly from USA to South America?

Use this chart to determine the cheapest time to fly round-trip from USA to South America. Price data was last updated on February 21, 2026.

Travelers seeking maximum savings on their USA to South America flight should consider departing on Saturday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 14, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,291 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.5
Good
1,570 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,918 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,464 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Avianca
6.5
Okay
2,499 reviews
Delta
7.9
Good
8,291 reviews

Crew

8.5

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from USA to South America?

    Departing from USA to South America will take you 3h 16m. The distance between USA and South America is about 1409 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from USA to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $46. However, be on the lookout for offers from JetBlue and Avianca, as they are both options that can get you from USA to South America for a low price.

  • Can I find deals for flights from USA to South America that include hotel bookings?

    Yes. In addition to deals on USA to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to South America.

  • Can I find deals for business class flights from USA to South America?

    Yes. Cheapflights offers flight deals from USA to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to South America?

    Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $78). Flying from USA to South America in December is currently the most expensive (average of $226). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for USA to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from USA to South America

Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$54Average$127FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$104Average$388FlexibilityNo cancel feeOn-time65%
ArajetCheapest$106Average$436FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$117Average$808FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$126Average$580FlexibilityNo cancel feeOn-time71%
VolarisCheapest$132Average$199FlexibilityNo cancel feeOn-time79%
LATAM AirlinesCheapest$142Average$756FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$150Average$750FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$154Average$530FlexibilityNo cancel feeOn-time62%
Copa AirlinesCheapest$154Average$659FlexibilityNo cancel feeOn-time70%

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