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South America

$65+ Cheap flights from the United States to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from USA to South America

Keep the following information in mind while searching for USA to South America flight deals. Data was last updated September 17, 2025.

Round-trip from

$187
(Cheapflightsfares)

One-way from

$65
(Booking.com)

Popular in

December

Cheapest in

September

Average price

$661

Good round-trip deal

$200 or less

Good one-way deal

$69 or less
From USA to South America
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One-way flight from USA to South America
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Highest demand for flights based on searches. 16% potential increase in price ($151 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from USA to South America.
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Price to beat on a one-way flight from USA to South America.
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Find flight deals from USA to South America

Cheapest flights from USA to South America
Explore the most affordable flight options available from USA to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Fri 10/171:59 pmMDE - FLL
1 stop6h 39mSpirit Airlines
Deal found 9/17$187
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Wed 10/151:16 amMDE - FLL
Nonstop3h 24mSpirit Airlines
Deal found 9/15$188
This Spirit deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Thu 11/133:11 pmMDE - FLL
Nonstop3h 39mSpirit Airlines
Deal found 9/17$190
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:00 pmFLL - MDE
Nonstop3h 28mSpirit Airlines
Fri 10/102:22 pmMDE - FLL
Nonstop3h 28mSpirit Airlines
Deal found 9/16$191
This Spirit deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2810:48 amFLL - MDE
Nonstop3h 26mSpirit Airlines
Thu 10/91:59 pmMDE - FLL
1 stop16h 06mSpirit Airlines
Deal found 9/15$192
This Spirit deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Spirit is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Mon 10/201:16 amMDE - FLL
Nonstop3h 24mSpirit Airlines
Deal found 9/17$193
This KAYAK deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Thu 10/161:16 amMDE - FLL
Nonstop3h 24mSpirit Airlines
Deal found 9/15$194
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:55 amFLL - MDE
Nonstop3h 16mSpirit Airlines
Thu 10/91:16 amMDE - FLL
Nonstop3h 24mSpirit Airlines
Deal found 9/17$195
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/92:39 pmFLL - MDE
Nonstop3h 25mSpirit Airlines
Sun 11/166:59 pmMDE - FLL
Nonstop3h 38mSpirit Airlines
Deal found 9/15$197
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:48 amFLL - MDE
Nonstop3h 26mSpirit Airlines
Thu 10/301:16 amMDE - FLL
Nonstop3h 24mSpirit Airlines
Deal found 9/16$198
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/310:09 pmFLL - MDE
Nonstop3h 12mSpirit Airlines
Tue 11/43:22 pmMDE - FLL
Nonstop3h 28mSpirit Airlines
Deal found 9/14$199
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:00 pmFLL - MDE
Nonstop3h 28mSpirit Airlines
Sun 10/52:22 pmMDE - FLL
Nonstop3h 28mSpirit Airlines
Deal found 9/15$200

Cheapflights Fare Finder

 
Customize your flight search to find flights from USA to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from the United States to South America that are best for you.

Fly from

USA

Fly to

South America

Route

Depart

Return

Price

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Tue 11/11

7:30 am-1:55 pm

1 stop6h 25m

Medellín Jose Maria Cordova Intl

Sat 11/15

6:59 pm-10:37 pm

Nonstop3h 38m

$211

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Fri 10/24

10:09 pm-12:21 am

Nonstop3h 12m

Medellín Jose Maria Cordova Intl

Sun 10/26

1:16 am-5:40 am

Nonstop3h 24m

$214

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Fri 10/17

10:09 pm-12:21 am

Nonstop3h 12m

Medellín Jose Maria Cordova Intl

Sun 10/19

1:16 am-5:40 am

Nonstop3h 24m

$214

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Thu 10/9

10:09 pm-12:21 am

Nonstop3h 12m

Medellín Jose Maria Cordova Intl

Mon 10/13

1:16 am-5:40 am

Nonstop3h 24m

$215

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Sun 9/28

7:00 am-1:00 pm

1 stop7h 00m

Medellín Jose Maria Cordova Intl

Thu 10/9

1:59 pm-7:05 am

1 stop16h 06m

$240

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Thu 10/2

10:00 pm-12:28 am

Nonstop3h 28m

Medellín Jose Maria Cordova Intl

Sat 10/11

1:16 am-5:40 am

Nonstop3h 24m

$249

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 10/30

6:30 am-9:00 am

Nonstop3h 30m

Medellín Jose Maria Cordova Intl

Thu 11/6

9:00 pm-3:10 am

1 stop6h 10m

$255

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Sun 9/28

7:00 am-1:00 pm

1 stop7h 00m

Medellín Jose Maria Cordova Intl

Mon 9/29

1:24 am-6:00 am

Nonstop3h 36m

$255

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Sun 11/2

11:00 am-2:32 pm

Nonstop3h 32m

Medellín Jose Maria Cordova Intl

Thu 11/13

2:10 pm-5:41 pm

Nonstop3h 31m

$260

Fort LauderdaleMedellín

FLL - MDE

FLLMDE

Fort Lauderdale

Tue 11/4

11:00 am-2:32 pm

Nonstop3h 32m

Medellín Jose Maria Cordova Intl

Thu 11/13

2:10 pm-5:41 pm

Nonstop3h 31m

$260

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 60 results
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Best time to book a flight from USA to South America

Have a flexible travel schedule? Discover the best time to fly to South America from USA with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the United States to South America

What is the cheapest month to book a flight from USA to South America?

Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $359). Flying from USA to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from US to SA?

Find hourly flight availability from USA to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from USA to South America as you normally would.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated September 17, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and LATAM Airlines from the United States to South America by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.6
Good
1,533 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,849 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,436 reviews
Delta
8.0
Very good
7,961 reviews

Entertainment

7.9

Comfort

7.9

Overall

8.0

Crew

8.5

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from USA to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this USA to South America flight route?

    The United States to South America flight path was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from USA to South America?

    Departing from USA to South America will take you 3h 30m. The distance between USA and South America is about 1393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from USA to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $74. However, be on the lookout for offers from Avianca and Delta, as they are both options that can get you from USA to South America for a low price.

  • Can I find deals for flights from USA to South America that include hotel bookings?

    Yes. In addition to deals on USA to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from USA to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from USA to South America.

  • Can I find deals for business class flights from USA to South America?

    Yes. Cheapflights offers flight deals from USA to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from USA to South America?

    Currently, May is the cheapest month in which you can book a flight from USA to South America (average of $359). Flying from USA to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for USA to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from USA to South America

Discover the top 10 airlines that operate flights from USA to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$78Average$98FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$102Average$455FlexibilityNo cancel feeOn-time65%
ArajetCheapest$116Average$438FlexibilityNo cancel feeOn-timeN/A
VolarisCheapest$143Average$320FlexibilityNo cancel feeOn-time79%
United AirlinesCheapest$150Average$842FlexibilityNo cancel feeOn-time69%
DeltaCheapest$171Average$807FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$184Average$579FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$222Average$690FlexibilityNo cancel feeOn-time70%
AzulCheapest$241Average$1,097FlexibilityNo cancel feeOn-time82%
American AirlinesCheapest$252Average$785FlexibilityNo cancel feeOn-time71%

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