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South America

$112+ Cheap flights from Pittsburgh (PIT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — BOG
Feb 22 — Mar 11
Sun 2/22
Sun 3/1
1 adult, Economy
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Cheap flight deals from Pittsburgh to South America

Cheapest flights from Pittsburgh to South America
Explore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 23, 2026.

This Cheapflightsfares deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
PIT
-
MDE
1 stop8h 13m
Spirit Airlines
Fri 3/63:15 pm
MDE
-
PIT
1 stop8h 44m
Spirit Airlines
Deal found 1/22$225
This Orbitz deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/246:00 am
PIT
-
CTG
1 stop7h 10m
Spirit Airlines
Tue 3/32:21 pm
CTG
-
PIT
1 stop9h 38m
Spirit Airlines
Deal found 1/21$235
This Expedia deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
-
CTG
1 stop7h 10m
Spirit Airlines
Tue 3/101:21 pm
CTG
-
PIT
1 stop9h 38m
Spirit Airlines
Deal found 1/21$257
This Orbitz deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:00 am
PIT
-
CTG
1 stop7h 10m
Spirit Airlines
Wed 3/42:21 pm
CTG
-
PIT
1 stop9h 38m
Spirit Airlines
Deal found 1/21$260
This JetBlue deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/216:00 am
PIT
-
CTG
1 stop8h 40m
JetBlue
Sun 3/12:35 pm
CTG
-
PIT
1 stop8h 17m
JetBlue
Deal found 1/22$265
This American Airlines deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:05 am
PIT
-
CTG
2 stops9h 25m
American Airlines
Tue 3/103:15 pm
CTG
-
PIT
2 stops20h 44m
American Airlines
Deal found 1/21$270
This CheapOair deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:45 am
PIT
-
MDE
1 stop14h 36m
Spirit Airlines
Wed 4/810:49 am
MDE
-
PIT
2 stops21h 49m
Spirit Airlines
Deal found 1/22$275
This Cheapflightsfares deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:00 am
PIT
-
MDE
1 stop8h 22m
Spirit Airlines
Wed 3/252:17 pm
MDE
-
PIT
1 stop18h 21m
Spirit Airlines
Deal found 1/20$276
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:15 pm
PIT
-
CTG
1 stop20h 00m
American Airlines
Fri 3/131:28 pm
CTG
-
PIT
2 stops19h 46m
American Airlines
Deal found 1/22$277
This Kiwi.com deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:45 am
PIT
-
MDE
1 stop14h 36m
Spirit Airlines
Wed 4/82:17 pm
MDE
-
PIT
1 stop18h 21m
Spirit Airlines
Deal found 1/22$287
This Orbitz deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
PIT
-
CTG
1 stop7h 13m
Spirit Airlines
Thu 4/301:21 pm
CTG
-
PIT
1 stop9h 21m
Spirit Airlines
Deal found 1/22$293
This United Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/17:00 am
PIT
-
MDE
2 stops15h 05m
United Airlines
Thu 2/510:45 am
MDE
-
PIT
2 stops23h 02m
United Airlines
Deal found 1/22$311

Find flight deals from Pittsburgh to South America

Keep the following information in mind while searching for Pittsburgh to South America flight deals. Data was last updated January 23, 2026.

Round-trip from

$225
(Cheapflightsfares)

One-way from

$112
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$503
From Pittsburgh to South America
Search Deals
One-way flight from Pittsburgh to South America
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Pittsburgh

Fly to

South America

Route

Depart

Return

Price

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 3/2

9:09 pm-2:13 pm

1 stop17h 04m

Medellín Jose Maria Cordova Intl

Fri 3/6

3:15 pm-11:59 pm

1 stop8h 44m

$226

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Wed 2/25

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

Wed 3/4

2:21 pm-11:59 pm

1 stop9h 38m

$260

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 3/30

10:45 am-12:21 am

1 stop14h 36m

Medellín Jose Maria Cordova Intl

Wed 4/8

2:17 pm-9:38 am

1 stop18h 21m

$261

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 2/21

6:00 am-2:40 pm

1 stop8h 40m

Cartagena Rafael Nunez

Sun 3/1

2:35 pm-10:52 pm

1 stop8h 17m

$265

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sun 4/19

7:39 pm-12:09 pm

2 stops17h 30m

Cartagena Rafael Nunez

Thu 4/30

1:25 pm-10:13 am

2 stops19h 48m

$270

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Mon 3/9

7:34 pm-12:27 pm

2 stops17h 53m

Cartagena Rafael Nunez

Fri 3/13

1:28 pm-10:14 am

2 stops19h 46m

$270

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Tue 2/24

4:45 pm-1:30 pm

2 stops20h 45m

Cartagena Rafael Nunez

Tue 3/3

2:30 pm-11:06 am

2 stops20h 36m

$270

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Tue 2/24

6:00 am-1:10 pm

1 stop7h 10m

Cartagena Rafael Nunez

Tue 3/3

2:21 pm-4:39 pm

2 stops26h 18m

$291

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sun 4/19

6:00 am-12:13 pm

1 stop7h 13m

Cartagena Rafael Nunez

Thu 4/30

1:21 pm-11:42 pm

1 stop9h 21m

$293

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/23

6:00 am-10:05 pm

1 stop16h 05m

Medellín Jose Maria Cordova Intl

Mon 3/2

10:45 am-1:09 pm

2 stops26h 24m

$311

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/21

Showing 1-10 of 60 results
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Best time to book a flight from Pittsburgh to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to South America

What is the cheapest month to book a flight from Pittsburgh to South America?

Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in June is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 23, 2026.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Pittsburgh to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,088 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,913 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,176 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,890 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,365 reviews
Delta
7.9
Good
8,088 reviews

Crew

8.5

Food

7.2

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Pittsburgh to South America?

    Most people fly from Pittsburgh (PIT) if they book a flight from Pittsburgh to South America. Pittsburgh is conveniently located just 13.5 mi from Pittsburgh’s city center.

  • How long is the flight from Pittsburgh to South America?

    Departing from Pittsburgh to South America will take you 8h 40m. Airlines will cover a distance of 2095 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Pittsburgh to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from JetBlue and American Airlines, as they are both options that can get you from Pittsburgh to South America for a low price.

  • What are the most popular routes from Pittsburgh to South America?

    While some choose either Pittsburgh - Quito Mariscal Sucr or Pittsburgh - Cartagena Rafael Nunez, Pittsburgh - Medellín Jose Maria Cordova Intl is the most popular route from Pittsburgh to South America.

  • Can I find deals for flights from Pittsburgh to South America that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to South America.

  • Can I find deals for business class flights from Pittsburgh to South America?

    Yes. Cheapflights offers flight deals from Pittsburgh to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to South America?

    Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in June is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Pittsburgh to South America

Discover the top 7 airlines that operate flights from Pittsburgh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$265Average$375FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$333Average$373FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$458Average$707FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$866FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$575Average$968FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$712Average$947FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$798Average$1,278FlexibilityNo cancel feeOn-time69%

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