$119+ Cheap flights from Pittsburgh (PIT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — BOG
Mar 22 — Mar 291
1 adult, Economy
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Find cheap flights from Pittsburgh to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to South America
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Cheapest flights from Pittsburgh to South AmericaExplore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.
Explore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 20, 2026.
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:19 pm
PIT
- CTG
2 stops21h 56m
American Airlines
Thu 3/191:28 pm
CTG
- PIT
1 stop8h 18m
American Airlines
Deal found 2/16![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:15 pm
PIT
- CTG
1 stop20h 00m
American Airlines
Thu 3/261:28 pm
CTG
- PIT
2 stops18h 43m
American Airlines
Deal found 2/16![American Airlines logo]()
$307
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- MDE
1 stop19h 21m
Spirit Airlines
Thu 3/192:17 pm
MDE
- PIT
1 stop8h 07m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$319
This KAYAK deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:30 am
PIT
- CTG
1 stop6h 30m
JetBlue
Wed 9/22:05 pm
CTG
- PIT
1 stop8h 34m
JetBlue
Deal found 2/17![JetBlue logo]()
$321
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:16 pm
PIT
- CTG
1 stop19h 48m
American Airlines
Sun 5/103:10 pm
CTG
- PIT
2 stops20h 54m
American Airlines
Deal found 2/20![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:16 pm
PIT
- CTG
1 stop19h 48m
American Airlines
Mon 5/183:10 pm
CTG
- PIT
1 stop26h 18m
American Airlines
Deal found 2/18![American Airlines logo]()
$331
This KAYAK deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:30 am
PIT
- CTG
1 stop6h 30m
JetBlue
Wed 9/22:05 pm
CTG
- PIT
1 stop8h 34m
JetBlue
Deal found 2/17![JetBlue logo]()
$337
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:45 am
PIT
- MDE
1 stop14h 36m
Spirit Airlines
Wed 3/251:17 am
MDE
- PIT
1 stop21h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$338
This Cheapflightsfares deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:00 am
PIT
- MDE
1 stop8h 10m
JetBlue
Wed 4/221:20 pm
MDE
- PIT
1 stop8h 25m
JetBlue
Deal found 2/18![JetBlue logo]()
$346
This KAYAK deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:30 am
PIT
- MDE
1 stop7h 25m
JetBlue
Fri 4/241:20 pm
MDE
- PIT
1 stop8h 25m
JetBlue
Deal found 2/18![JetBlue logo]()
$347
This Travelocity deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- MDE
1 stop8h 22m
Spirit Airlines
Fri 3/202:17 pm
MDE
- PIT
1 stop8h 07m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$349
This KAYAK deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:30 am
PIT
- CTG
1 stop6h 30m
JetBlue
Fri 8/282:05 pm
CTG
- PIT
1 stop8h 34m
JetBlue
Deal found 2/17![JetBlue logo]()
$350
Best flights from Pittsburgh to South AmericaDiscover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2026.
Discover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 20, 2026.
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:57 pm
PIT
- CTG
2 stops19h 07m
American Airlines
Sun 5/103:10 pm
CTG
- PIT
2 stops17h 33m
American Airlines
Deal found 2/17![American Airlines logo]()
$300
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1610:45 am
PIT
- MDE
1 stop14h 36m
Spirit Airlines
Thu 3/191:17 am
MDE
- PIT
1 stop21h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$319
This KAYAK deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:30 am
PIT
- CTG
1 stop6h 30m
JetBlue
Wed 9/22:05 pm
CTG
- PIT
1 stop8h 34m
JetBlue
Deal found 2/17![JetBlue logo]()
$321
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- MDE
1 stop16h 05m
United Airlines
Thu 3/199:45 am
MDE
- PIT
1 stop12h 30m
United Airlines
Deal found 2/17![United Airlines logo]()
$347
This LATAM Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:23 am
PIT
- UIO
2 stops29h 27m
LATAM Airlines
Wed 3/1811:45 pm
UIO
- PIT
1 stop17h 44m
LATAM Airlines
Deal found 2/16![LATAM Airlines logo]()
$560
This Mytrip deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:40 am
PIT
- LIM
3 stops33h 50m
Multiple Airlines
Tue 3/2410:35 pm
LIM
- PIT
3 stops23h 20m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$571
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:53 pm
PIT
- CTG
2 stops18h 34m
American Airlines
Thu 3/191:28 pm
CTG
- PIT
2 stops18h 43m
American Airlines
Deal found 2/16![American Airlines logo]()
$300
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- LIM
1 stop16h 20m
Delta
Wed 5/2012:05 am
LIM
- PIT
1 stop14h 24m
Delta
Deal found 2/16![Delta logo]()
$615
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:45 pm
PIT
- CTG
2 stops19h 19m
American Airlines
Mon 5/183:10 pm
CTG
- PIT
1 stop26h 18m
American Airlines
Deal found 2/17![American Airlines logo]()
$307
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:45 am
PIT
- MDE
1 stop14h 36m
Spirit Airlines
Wed 3/251:17 am
MDE
- PIT
1 stop21h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$338
This Air Canada deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/95:55 pm
PIT
- SCL
1 stop16h 20m
Air Canada
Wed 3/187:55 pm
SCL
- PIT
1 stop22h 21m
Air Canada
Deal found 2/18![Air Canada logo]()
$711
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:40 pm
PIT
- MDE
2 stops25h 30m
United Airlines
Sun 5/109:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/20![United Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:15 pm
PIT
- CTG
1 stop18h 12m
American Airlines
Thu 3/261:28 pm
CTG
- PIT
2 stops18h 43m
American Airlines
Deal found 2/16![American Airlines logo]()
$307
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:45 pm
PIT
- MDE
1 stop9h 25m
United Airlines
Fri 4/249:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/18![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:45 pm
PIT
- MDE
1 stop9h 25m
United Airlines
Sat 4/259:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/18![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:45 pm
PIT
- MDE
1 stop9h 25m
United Airlines
Sat 4/259:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/18![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1012:45 pm
PIT
- MDE
1 stop9h 25m
United Airlines
Tue 4/149:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/17![United Airlines logo]()
$367
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:00 am
PIT
- MDE
1 stop16h 10m
United Airlines
Fri 4/249:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 2/18![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:10 am
PIT
- LIM
1 stop19h 50m
Delta
Thu 5/2812:00 pm
LIM
- PIT
1 stop11h 45m
Delta
Deal found 2/16![Delta logo]()
$615
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/119:41 am
PIT
- UIO
2 stops23h 41m
Multiple Airlines
Sun 4/196:40 pm
UIO
- PIT
3 stops21h 11m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$626
This Gurufare deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:05 am
PIT
- UIO
1 stop12h 54m
LATAM Airlines
Sat 4/1812:59 am
UIO
- PIT
1 stop11h 02m
LATAM Airlines
Deal found 2/17![LATAM Airlines logo]()
$626
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
- MDE
1 stop16h 05m
United Airlines
Fri 3/610:45 am
MDE
- PIT
1 stop12h 30m
United Airlines
Deal found 2/17![United Airlines logo]()
$370
This Cheapflightsfares deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
PIT
- LIM
1 stop16h 35m
Spirit Airlines
Tue 3/2410:35 pm
LIM
- PIT
1 stop10h 03m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$606
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:10 am
PIT
- LIM
1 stop12h 10m
Delta
Tue 5/1912:10 am
LIM
- PIT
2 stops23h 35m
Delta
Deal found 2/16![Delta logo]()
$615
This Mytrip deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 am
PIT
- UIO
2 stops26h 26m
Multiple Airlines
Thu 4/163:30 am
UIO
- PIT
3 stops19h 28m
Multiple Airlines
Deal found 2/17![Multiple Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1812:45 pm
PIT
- MDE
1 stop9h 25m
United Airlines
Wed 4/229:45 am
MDE
- PIT
2 stops23h 03m
United Airlines
Deal found 2/18![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- LIM
1 stop16h 20m
Delta
Tue 5/268:55 am
LIM
- PIT
2 stops14h 50m
Delta
Deal found 2/16![Delta logo]()
$615
This LATAM Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:23 am
PIT
- SCL
1 stop17h 32m
LATAM Airlines
Wed 3/185:15 am
SCL
- PIT
2 stops20h 02m
LATAM Airlines
Deal found 2/18![LATAM Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:05 am
PIT
- LIM
1 stop15h 15m
Delta
Tue 5/2612:00 pm
LIM
- PIT
1 stop11h 45m
Delta
Deal found 2/16![Delta logo]()
$615
This Avianca Connect deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:15 pm
PIT
- GRU
2 stops21h 50m
Multiple Airlines
Thu 5/212:20 am
GRU
- PIT
2 stops22h 38m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$722
Last-minute flights from Pittsburgh to South AmericaDiscover last-minute flight deals from Pittsburgh to South America. Data last updated February 20, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to South America. Data last updated February 20, 2026 and is based on user searches.
This JetBlue deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
PIT
- MDE
1 stop7h 45m
JetBlue
Thu 2/262:25 pm
MDE
- PIT
1 stop8h 27m
JetBlue
Deal found 2/16![JetBlue logo]()
$347
This United Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:19 am
PIT
- MDE
2 stops14h 46m
United Airlines
Thu 2/2610:45 am
MDE
- PIT
2 stops23h 01m
United Airlines
Deal found 2/16![United Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:33 pm
PIT
- CTG
2 stops18h 57m
American Airlines
Fri 3/64:30 pm
CTG
- PIT
2 stops16h 12m
American Airlines
Deal found 2/16![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
- MDE
1 stop16h 05m
United Airlines
Fri 3/610:45 am
MDE
- PIT
1 stop12h 30m
United Airlines
Deal found 2/17![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/145:19 pm
PIT
- CTG
2 stops21h 56m
American Airlines
Thu 3/191:28 pm
CTG
- PIT
1 stop8h 18m
American Airlines
Deal found 2/16![American Airlines logo]()
$300
This KAYAK deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1412:24 pm
PIT
- CTG
1 stop25h 51m
LATAM Airlines
Thu 3/192:30 pm
CTG
- PIT
1 stop8h 47m
LATAM Airlines
Deal found 2/20![LATAM Airlines logo]()
$366
This CheapOair deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- MDE
1 stop19h 21m
Spirit Airlines
Thu 3/192:17 pm
MDE
- PIT
1 stop8h 07m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$319
This Gurufare deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- CTG
1 stop8h 15m
LATAM Airlines
Fri 3/204:35 am
CTG
- PIT
2 stops28h 06m
LATAM Airlines
Deal found 2/20![LATAM Airlines logo]()
$369
This CheapOair deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1510:45 am
PIT
- CTG
1 stop26h 21m
Spirit Airlines
Fri 3/201:14 pm
CTG
- PIT
1 stop9h 10m
Spirit Airlines
Deal found 2/16![Spirit Airlines logo]()
$372
This Travelocity deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- MDE
1 stop8h 22m
Spirit Airlines
Fri 3/202:17 pm
MDE
- PIT
1 stop8h 07m
Spirit Airlines
Deal found 2/18![Spirit Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:15 pm
PIT
- CTG
1 stop20h 00m
American Airlines
Thu 3/261:28 pm
CTG
- PIT
2 stops18h 43m
American Airlines
Deal found 2/16![American Airlines logo]()
$307
This CheapOair deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:45 am
PIT
- MDE
1 stop14h 36m
Spirit Airlines
Wed 3/251:17 am
MDE
- PIT
1 stop21h 07m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$338
One-way flights from Pittsburgh to South AmericaSearch for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated February 20, 2026.
Search for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated February 20, 2026.
This Priceline deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
- MDE
1 stop8h 13m
Spirit Airlines
Deal found 2/17![Spirit Airlines logo]()
$119
This American Airlines deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:00 am
PIT
- CTG
1 stop9h 15m
American Airlines
Deal found 2/16![American Airlines logo]()
$121
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/146:53 pm
PIT
- CTG
2 stops20h 22m
American Airlines
Deal found 2/19![American Airlines logo]()
$137
This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:05 am
PIT
- MDE
2 stops12h 05m
American Airlines
Deal found 2/17![American Airlines logo]()
$148
This KAYAK deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1412:24 pm
PIT
- CTG
1 stop25h 51m
LATAM Airlines
Deal found 2/19![LATAM Airlines logo]()
$166
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/233:00 pm
PIT
- MDE
2 stops31h 10m
United Airlines
Deal found 2/19![United Airlines logo]()
$178
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1410:45 am
PIT
- CTG
3 stops30h 58m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$181
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PIT
- MDE
3 stops16h 55m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:46 pm
PIT
- MDE
3 stops41h 03m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:45 am
PIT
- CTG
2 stops37h 03m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
PIT
- UIO
2 stops25h 51m
Multiple Airlines
Deal found 2/18![Multiple Airlines logo]()
$264
This Mytrip deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/72:55 pm
PIT
- UIO
3 stops34h 25m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$277
Find flight deals from Pittsburgh to South America
Keep the following information in mind while searching for Pittsburgh to South America flight deals. Data was last updated February 20, 2026.
Round-trip from | $300 (American Airlines) |
|---|---|
One-way from | $119 (Priceline) |
Popular in | December |
Cheapest in | September |
Average price | $520 |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.
Fly from
Pittsburgh
Fly to
South America
Route
Depart
Return
Price
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sat 5/2
7:57 pm-2:04 pm
2 stops19h 07m
Cartagena Rafael Nunez
Sun 5/10
3:10 pm-9:43 am
2 stops17h 33m
$300
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sat 3/14
6:53 pm-12:27 pm
2 stops18h 34m
Cartagena Rafael Nunez
Thu 3/19
1:28 pm-9:11 am
2 stops18h 43m
$300
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Thu 5/14
7:45 pm-2:04 pm
2 stops19h 19m
Cartagena Rafael Nunez
Mon 5/18
3:10 pm-6:28 pm
1 stop26h 18m
$307
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sun 3/22
7:15 pm-12:27 pm
1 stop18h 12m
Cartagena Rafael Nunez
Thu 3/26
1:28 pm-9:11 am
2 stops18h 43m
$307
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Mon 3/16
10:45 am-12:21 am
1 stop14h 36m
Medellín Jose Maria Cordova Intl
Thu 3/19
1:17 am-11:24 pm
1 stop21h 07m
$319
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Wed 8/19
7:30 am-1:00 pm
1 stop6h 30m
Cartagena Rafael Nunez
Wed 9/2
2:05 pm-11:39 pm
1 stop8h 34m
$321
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Sun 3/22
10:45 am-12:21 am
1 stop14h 36m
Medellín Jose Maria Cordova Intl
Wed 3/25
1:17 am-11:24 pm
1 stop21h 07m
$338
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Sun 3/15
6:00 am-9:05 pm
1 stop16h 05m
Medellín Jose Maria Cordova Intl
Thu 3/19
9:45 am-11:15 pm
1 stop12h 30m
$347
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Fri 5/1
8:40 pm-9:10 pm
2 stops25h 30m
Medellín Jose Maria Cordova Intl
Sun 5/10
9:45 am-11:44 pm
1 stop12h 59m
$358
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Sat 4/18
12:45 pm-9:10 pm
1 stop9h 25m
Medellín Jose Maria Cordova Intl
Fri 4/24
9:45 am-11:44 pm
1 stop12h 59m
$367
Showing 1-10 of 60 results
Best time to book a flight from Pittsburgh to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Pittsburgh with our price prediction graph.
PIT-CTG
PIT-MDE
PIT-UIO
PIT-LIM
PIT-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to South America
PIT-0SA
PIT-CTG
PIT-MDE
PIT-UIO
PIT-LIM
What is the cheapest month to book a flight from Pittsburgh to South America?
Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in July is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 20, 2026.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Pittsburgh to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Comfort
7.9
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Pittsburgh to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to South America by cabin class
Find flights from Pittsburgh to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and South America flights
Browse other Pittsburgh and South America flight options. Last updated on February 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Pittsburgh to South America flights
Consider these flights traveling from Pittsburgh to South America.
Top 7 airlines flying from Pittsburgh to South America
Discover the top 7 airlines that operate flights from Pittsburgh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$265 | Average$412 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$333 | Average$373 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$359 | Average$911 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$402 | Average$683 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$575 | Average$967 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$712 | Average$947 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$1,080 | Average$1,278 | FlexibilityNo cancel fee | On-time69% |