$121+ Cheap flights from Pittsburgh (PIT) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — BOG
Apr 6 — Apr 131
Round-trip
1 adult, Economy
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Find cheap flights from Pittsburgh to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Pittsburgh to South America
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Cheapest flights from Pittsburgh to South AmericaExplore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
Explore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 7, 2026.
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:39 pm
PIT
- CTG
2 stops19h 25m
American Airlines
Tue 5/121:25 pm
CTG
- PIT
2 stops22h 39m
American Airlines
Deal found 3/3![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:16 pm
PIT
- CTG
1 stop17h 53m
American Airlines
Sun 5/103:10 pm
CTG
- PIT
1 stop7h 49m
American Airlines
Deal found 3/3![American Airlines logo]()
$303
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:16 pm
PIT
- CTG
1 stop19h 48m
American Airlines
Mon 5/113:10 pm
CTG
- PIT
1 stop26h 18m
American Airlines
Deal found 3/5![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:45 pm
PIT
- CTG
2 stops17h 24m
American Airlines
Mon 5/113:10 pm
CTG
- PIT
1 stop26h 18m
American Airlines
Deal found 3/6![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:45 pm
PIT
- CTG
2 stops20h 42m
American Airlines
Tue 3/311:35 pm
CTG
- PIT
2 stops19h 39m
American Airlines
Deal found 3/5![American Airlines logo]()
$329
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
PIT
- BOG
1 stop8h 11m
Spirit Airlines
Wed 4/82:10 pm
BOG
- PIT
1 stop18h 28m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$332
This Cheapflightsfares deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- BOG
1 stop8h 11m
Spirit Airlines
Thu 3/192:10 pm
BOG
- PIT
1 stop8h 14m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$333
This KAYAK deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
PIT
- CTG
1 stop8h 55m
JetBlue
Wed 4/12:15 pm
CTG
- PIT
1 stop7h 25m
JetBlue
Deal found 3/2![JetBlue logo]()
$339
This Cheapflightsfares deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:35 am
PIT
- MDE
1 stop7h 33m
Spirit Airlines
Wed 5/132:06 pm
MDE
- PIT
1 stop8h 53m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- MDE
1 stop17h 39m
American Airlines
Fri 3/207:00 am
MDE
- PIT
1 stop14h 46m
American Airlines
Deal found 3/3![American Airlines logo]()
$347
This Expedia deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:35 am
PIT
- CTG
1 stop6h 31m
Spirit Airlines
Mon 5/181:11 pm
CTG
- PIT
1 stop9h 48m
Spirit Airlines
Deal found 3/5![Spirit Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:45 am
PIT
- CTG
1 stop26h 21m
Spirit Airlines
Wed 4/11:14 pm
CTG
- PIT
1 stop7h 24m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$350
Best flights from Pittsburgh to South AmericaDiscover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
Discover carefully curated flight deals from Pittsburgh to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 7, 2026.
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:16 pm
PIT
- CTG
1 stop17h 53m
American Airlines
Sun 5/101:25 pm
CTG
- PIT
1 stop9h 34m
American Airlines
Deal found 3/6![American Airlines logo]()
$303
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:58 pm
PIT
- MDE
2 stops28h 12m
United Airlines
Sun 5/109:45 am
MDE
- PIT
2 stops23h 08m
United Airlines
Deal found 3/3![United Airlines logo]()
$358
This BusinessClass deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
PIT
- CTG
2 stops13h 45m
LATAM Airlines
Sun 8/2310:10 am
CTG
- PIT
2 stops31h 33m
LATAM Airlines
Deal found 3/6![LATAM Airlines logo]()
$370
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/227:05 am
PIT
- CTG
1 stop7h 10m
Delta
Tue 3/314:25 am
CTG
- PIT
2 stops18h 52m
Delta
Deal found 3/2![Delta logo]()
$382
This Orbitz deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/226:00 am
PIT
- CTG
1 stop8h 50m
JetBlue
Mon 4/272:05 pm
CTG
- PIT
1 stop7h 40m
JetBlue
Deal found 3/2![JetBlue logo]()
$397
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:45 am
PIT
- CTG
1 stop26h 21m
Spirit Airlines
Mon 4/131:14 pm
CTG
- PIT
1 stop19h 24m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:15 pm
PIT
- BOG
1 stop19h 57m
Multiple Airlines
Tue 5/1911:15 pm
BOG
- PIT
2 stops23h 44m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$490
This Air Canada deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:35 pm
PIT
- BOG
1 stop13h 30m
Air Canada
Sun 8/169:00 am
BOG
- PIT
2 stops28h 48m
Air Canada
Deal found 3/2![Air Canada logo]()
$589
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:45 pm
PIT
- CTG
2 stops17h 24m
American Airlines
Mon 5/113:10 pm
CTG
- PIT
1 stop26h 18m
American Airlines
Deal found 3/6![American Airlines logo]()
$328
This Copa Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:35 am
PIT
- LIM
2 stops15h 45m
Copa Airlines
Fri 5/84:40 pm
LIM
- PIT
2 stops26h 42m
Copa Airlines
Deal found 3/5![Copa Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
PIT
- MDE
1 stop16h 10m
United Airlines
Fri 4/249:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 3/3![United Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:50 pm
PIT
- CTG
1 stop18h 25m
Delta
Tue 5/122:13 pm
CTG
- PIT
1 stop9h 32m
Delta
Deal found 3/5![Delta logo]()
$385
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
PIT
- MDE
2 stops15h 15m
American Airlines
Tue 5/51:50 pm
MDE
- PIT
1 stop9h 09m
American Airlines
Deal found 3/3![American Airlines logo]()
$352
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/610:35 am
PIT
- MDE
2 stops11h 35m
United Airlines
Wed 5/139:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 3/4![United Airlines logo]()
$372
This KAYAK deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:45 am
PIT
- BAQ
1 stop27h 59m
Spirit Airlines
Tue 4/142:40 pm
BAQ
- PIT
1 stop17h 58m
Spirit Airlines
Deal found 3/5![Spirit Airlines logo]()
$433
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
PIT
- MDE
1 stop16h 10m
United Airlines
Thu 4/239:45 am
MDE
- PIT
2 stops28h 41m
United Airlines
Deal found 3/3![United Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
PIT
- CTG
1 stop8h 15m
Delta
Thu 4/22:30 pm
CTG
- PIT
1 stop8h 47m
Delta
Deal found 3/3![Delta logo]()
$431
This CheapOair deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 am
PIT
- CTG
1 stop7h 06m
Spirit Airlines
Tue 3/241:14 pm
CTG
- PIT
1 stop7h 24m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$438
This LATAM Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:05 am
PIT
- BOG
2 stops17h 35m
LATAM Airlines
Thu 3/197:00 am
BOG
- PIT
2 stops16h 17m
LATAM Airlines
Deal found 3/5![LATAM Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:45 am
PIT
- MDE
2 stops13h 25m
United Airlines
Thu 5/149:45 am
MDE
- PIT
1 stop12h 59m
United Airlines
Deal found 3/4![United Airlines logo]()
$372
This Mytrip deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:00 am
PIT
- BAQ
1 stop8h 44m
Multiple Airlines
Tue 4/146:25 am
BAQ
- PIT
2 stops26h 13m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$502
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:16 pm
PIT
- CTG
1 stop19h 48m
American Airlines
Tue 5/121:25 pm
CTG
- PIT
1 stop9h 34m
American Airlines
Deal found 3/4![American Airlines logo]()
$436
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2112:24 pm
PIT
- CTG
1 stop25h 51m
Delta
Thu 4/22:30 pm
CTG
- PIT
1 stop8h 47m
Delta
Deal found 3/3![Delta logo]()
$438
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/218:51 am
PIT
- MDE
2 stops37h 14m
United Airlines
Thu 4/29:45 am
MDE
- PIT
1 stop24h 30m
United Airlines
Deal found 3/2![United Airlines logo]()
$373
This Mytrip deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/36:35 am
PIT
- BOG
1 stop7h 37m
Multiple Airlines
Sun 5/310:50 pm
BOG
- PIT
2 stops17h 00m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$525
This CheapOair deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
PIT
- BOG
2 stops47h 05m
Air Canada
Tue 6/239:00 am
BOG
- PIT
2 stops25h 33m
Air Canada
Deal found 3/2![Air Canada logo]()
$653
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:15 am
PIT
- BOG
2 stops12h 50m
Multiple Airlines
Tue 5/129:05 am
BOG
- PIT
1 stop13h 54m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$546
This Copa Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
PIT
- LIM
2 stops19h 45m
Copa Airlines
Sun 6/144:40 pm
LIM
- PIT
2 stops27h 22m
Copa Airlines
Deal found 3/4![Copa Airlines logo]()
$673
This FlightHub deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:45 am
PIT
- LIM
1 stop11h 50m
Spirit Airlines
Tue 3/2410:35 pm
LIM
- PIT
1 stop10h 03m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$579
This Gotogate deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/175:55 pm
PIT
- LIM
2 stops32h 20m
Multiple Airlines
Tue 3/2410:35 pm
LIM
- PIT
1 stop10h 03m
Multiple Airlines
Deal found 3/6![Multiple Airlines logo]()
$586
Last-minute flights from Pittsburgh to South AmericaDiscover last-minute flight deals from Pittsburgh to South America. Data last updated March 7, 2026 and is based on user searches.
Discover last-minute flight deals from Pittsburgh to South America. Data last updated March 7, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- BOG
1 stop8h 11m
Spirit Airlines
Thu 3/192:10 pm
BOG
- PIT
1 stop8h 14m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
PIT
- MDE
1 stop17h 39m
American Airlines
Fri 3/207:00 am
MDE
- PIT
1 stop14h 46m
American Airlines
Deal found 3/3![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/216:00 am
PIT
- MDE
1 stop16h 05m
United Airlines
Fri 4/39:45 am
MDE
- PIT
1 stop24h 30m
United Airlines
Deal found 3/2![United Airlines logo]()
$355
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2210:45 am
PIT
- CTG
1 stop26h 21m
Spirit Airlines
Wed 4/11:14 pm
CTG
- PIT
1 stop7h 24m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$350
This KAYAK deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:00 am
PIT
- MDE
1 stop7h 49m
JetBlue
Wed 4/151:30 pm
MDE
- PIT
1 stop8h 15m
JetBlue
Deal found 3/4![JetBlue logo]()
$365
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
PIT
- CTG
1 stop9h 15m
American Airlines
Tue 3/311:35 pm
CTG
- PIT
2 stops19h 39m
American Airlines
Deal found 3/3![American Airlines logo]()
$300
This KAYAK deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
PIT
- CTG
1 stop8h 55m
JetBlue
Wed 4/12:15 pm
CTG
- PIT
1 stop7h 25m
JetBlue
Deal found 3/2![JetBlue logo]()
$339
This KAYAK deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
PIT
- CTG
1 stop7h 06m
Spirit Airlines
Wed 4/11:14 pm
CTG
- PIT
1 stop7h 24m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/247:05 am
PIT
- MDE
2 stops15h 00m
United Airlines
Thu 4/29:45 am
MDE
- PIT
1 stop24h 30m
United Airlines
Deal found 3/2![United Airlines logo]()
$360
This Cheapflightsfares deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:00 am
PIT
- BOG
1 stop8h 11m
Spirit Airlines
Wed 4/82:10 pm
BOG
- PIT
1 stop18h 28m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:05 am
PIT
- MDE
2 stops15h 10m
American Airlines
Tue 4/211:50 pm
MDE
- PIT
1 stop9h 09m
American Airlines
Deal found 3/5![American Airlines logo]()
$352
This Cheapflightsfares deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 am
PIT
- CTG
1 stop8h 50m
JetBlue
Fri 4/242:05 pm
CTG
- PIT
1 stop7h 40m
JetBlue
Deal found 3/3![JetBlue logo]()
$354
One-way flights from Pittsburgh to South AmericaSearch for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
Search for one-way flight options from Pittsburgh to South America. Find affordable one-way fares based on user searches. Data last updated March 7, 2026.
This American Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:58 pm
PIT
- CTG
2 stops19h 11m
American Airlines
Deal found 3/4![American Airlines logo]()
$121
This Super.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:35 am
PIT
- MDE
1 stop7h 33m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$145
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:12 am
PIT
- MDE
2 stops15h 03m
American Airlines
Deal found 3/3![American Airlines logo]()
$148
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:15 am
PIT
- MDE
2 stops12h 55m
United Airlines
Deal found 3/4![United Airlines logo]()
$158
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:59 pm
PIT
- MDE
2 stops26h 11m
United Airlines
Deal found 3/6![United Airlines logo]()
$164
This CheapOair deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 pm
PIT
- MDE
1 stop19h 53m
Spirit Airlines
Deal found 3/4![Spirit Airlines logo]()
$170
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:15 pm
PIT
- BOG
1 stop19h 57m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$170
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:52 pm
PIT
- MDE
2 stops50h 18m
United Airlines
Deal found 3/4![United Airlines logo]()
$184
This CheapOair deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:15 pm
PIT
- MDE
1 stop19h 53m
Spirit Airlines
Deal found 3/6![Spirit Airlines logo]()
$190
This Mytrip deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:35 am
PIT
- MDE
3 stops18h 00m
Multiple Airlines
Deal found 3/3![Multiple Airlines logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:52 am
PIT
- MDE
3 stops32h 48m
Multiple Airlines
Deal found 3/4![Multiple Airlines logo]()
$196
This United Airlines deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/267:59 pm
PIT
- MDE
2 stops26h 11m
United Airlines
Deal found 3/4![United Airlines logo]()
$209
Find flight deals from Pittsburgh to South America
Keep the following information in mind while searching for Pittsburgh to South America flight deals. Data was last updated March 7, 2026.
Round-trip from | $300 (American Airlines) |
|---|---|
One-way from | $121 (American Airlines) |
Popular in | December |
Cheapest in | March |
Average price | $386 |
Cheapflights Fare Finder
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Sat 5/2
7:16 pm-12:09 pm
1 stop17h 53m
Cartagena Rafael Nunez
Sun 5/10
1:25 pm-11:59 pm
1 stop9h 34m
$303
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Mon 5/4
7:45 pm-12:09 pm
2 stops17h 24m
Cartagena Rafael Nunez
Mon 5/11
3:10 pm-6:28 pm
1 stop26h 18m
$328
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Fri 5/1
6:00 am-8:15 pm
2 stops15h 15m
Medellín Jose Maria Cordova Intl
Tue 5/5
1:50 pm-11:59 pm
1 stop9h 09m
$352
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Fri 5/1
5:58 pm-9:10 pm
2 stops28h 12m
Medellín Jose Maria Cordova Intl
Sun 5/10
9:45 am-9:53 am
2 stops23h 08m
$358
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Fri 4/17
6:00 am-9:10 pm
1 stop16h 10m
Medellín Jose Maria Cordova Intl
Fri 4/24
9:45 am-11:44 pm
1 stop12h 59m
$367
PittsburghCartagena
PIT - CTG
PITCTG
Pittsburgh
Wed 8/19
6:00 am-6:45 pm
2 stops13h 45m
Cartagena Rafael Nunez
Sun 8/23
10:10 am-6:43 pm
2 stops31h 33m
$370
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Wed 5/6
10:35 am-9:10 pm
2 stops11h 35m
Medellín Jose Maria Cordova Intl
Wed 5/13
9:45 am-11:44 pm
1 stop12h 59m
$372
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Mon 4/20
6:00 am-9:10 pm
1 stop16h 10m
Medellín Jose Maria Cordova Intl
Thu 4/23
9:45 am-3:26 pm
2 stops28h 41m
$372
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Wed 5/6
8:45 am-9:10 pm
2 stops13h 25m
Medellín Jose Maria Cordova Intl
Thu 5/14
9:45 am-11:44 pm
1 stop12h 59m
$372
PittsburghMedellín
PIT - MDE
PITMDE
Pittsburgh
Sat 3/21
8:51 am-9:05 pm
2 stops37h 14m
Medellín Jose Maria Cordova Intl
Thu 4/2
9:45 am-11:15 am
1 stop24h 30m
$373
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Pittsburgh to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Pittsburgh with our price prediction graph.
PIT-CTG
PIT-MDE
PIT-BOG
PIT-LIM
PIT-BAQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Pittsburgh to South America
PIT-0SA
PIT-CTG
PIT-MDE
PIT-BOG
PIT-LIM
What is the cheapest month to book a flight from Pittsburgh to South America?
Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in July is currently the most expensive (average of $380). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated March 7, 2026.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and JetBlue from Pittsburgh to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Crew
8.5
Overall
7.9
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Pittsburgh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Pittsburgh to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Pittsburgh to South America by cabin class
Find flights from Pittsburgh to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Pittsburgh and South America flights
Browse other Pittsburgh and South America flight options. Last updated on March 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Pittsburgh to South America flights
Consider these flights traveling from Pittsburgh to South America.
Top 7 airlines flying from Pittsburgh to South America
Discover the top 7 airlines that operate flights from Pittsburgh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$279 | Average$413 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$333 | Average$373 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$347 | Average$882 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$359 | Average$908 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$392 | Average$685 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$575 | Average$950 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$617 | Average$937 | FlexibilityNo cancel fee | On-time70% |