HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
South America

$121+ Cheap flights from Pittsburgh (PIT) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — BOG
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Pittsburgh to South America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Pittsburgh to South America

Keep the following information in mind while searching for Pittsburgh to South America flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$242
(Expedia)

One-way from

$121
(JetBlue)
Provider with most accurate pricing for Pittsburgh-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pittsburgh-Sao Paulo (SAO) flights.
Search Deals
From Pittsburgh to South America
Search Deals
One-way flight from Pittsburgh to South America
Search Deals

Find flight deals from Pittsburgh to South America

Cheapest flights from Pittsburgh to South America
Explore the most affordable flight options available from Pittsburgh to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Expedia deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/209:09 pmPIT - CTG
1 stop16h 01mSpirit Airlines
Fri 2/272:21 pmCTG - PIT
1 stop9h 38mSpirit Airlines
Deal found 1/6$242
This Cheapflightsfares deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:00 amPIT - MDE
1 stop8h 15mSpirit Airlines
Tue 2/173:15 pmMDE - PIT
1 stop8h 44mSpirit Airlines
Deal found 1/8$248
This Cheapflightsfares deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/46:00 amPIT - MDE
1 stop8h 15mSpirit Airlines
Wed 2/183:15 pmMDE - PIT
1 stop8h 44mSpirit Airlines
Deal found 1/8$255
This JetBlue deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:00 amPIT - MDE
1 stop7h 55mJetBlue
Mon 2/162:25 pmMDE - PIT
1 stop8h 45mJetBlue
Deal found 1/7$258
This Cheapflightsfares deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:00 amPIT - LIM
1 stop16h 35mSpirit Airlines
Wed 2/1811:30 pmLIM - PIT
1 stop20h 44mSpirit Airlines
Deal found 1/7$266
This JetBlue deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/257:00 amPIT - CTG
1 stop7h 50mJetBlue
Thu 1/292:20 pmCTG - PIT
1 stop9h 35mJetBlue
Deal found 1/6$280
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:31 amPIT - MDE
2 stops13h 39mAmerican Airlines
Mon 3/3012:20 amMDE - PIT
1 stop17h 05mAmerican Airlines
Deal found 1/8$289
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/57:05 pmPIT - CTG
2 stops18h 25mAmerican Airlines
Mon 2/94:30 pmCTG - PIT
2 stops17h 57mAmerican Airlines
Deal found 1/7$294
This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/298:10 pmPIT - MDE
2 stops25h 55mUnited Airlines
Thu 2/510:45 amMDE - PIT
2 stops22h 48mUnited Airlines
Deal found 1/8$295
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:21 pmPIT - CTG
1 stop19h 43mAmerican Airlines
Sat 4/181:25 pmCTG - PIT
2 stops19h 48mAmerican Airlines
Deal found 1/8$301
This JetBlue deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/17:00 amPIT - MDE
1 stop7h 55mJetBlue
Thu 2/52:25 pmMDE - PIT
1 stop8h 23mJetBlue
Deal found 1/6$312
This United Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/22:09 pmPIT - MDE
2 stops31h 56mUnited Airlines
Thu 2/510:45 amMDE - PIT
2 stops23h 02mUnited Airlines
Deal found 1/7$322

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Pittsburgh to South America that are best for you.

Fly from

Pittsburgh

Fly to

South America

Route

Depart

Return

Price

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Tue 2/3

6:00 am-2:15 pm

1 stop8h 15m

Medellín Jose Maria Cordova Intl

Tue 2/17

3:15 pm-11:59 pm

1 stop8h 44m

$248

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Wed 2/11

7:00 am-2:55 pm

1 stop7h 55m

Medellín Jose Maria Cordova Intl

Mon 2/16

2:25 pm-11:10 pm

1 stop8h 45m

$258

PittsburghLima

PIT - LIM

PITLIM

Pittsburgh

Tue 2/3

6:00 am-10:35 pm

1 stop16h 35m

Lima J Chavez Intl

Wed 2/18

11:30 pm-8:14 pm

1 stop20h 44m

$266

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sun 1/25

7:00 am-2:50 pm

1 stop7h 50m

Cartagena Rafael Nunez

Thu 1/29

2:20 pm-11:55 pm

1 stop9h 35m

$280

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sun 3/1

7:31 am-9:10 pm

2 stops13h 39m

Medellín Jose Maria Cordova Intl

Mon 3/30

12:20 am-6:25 pm

1 stop17h 05m

$289

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Thu 2/5

7:05 pm-1:30 pm

2 stops18h 25m

Cartagena Rafael Nunez

Mon 2/9

4:30 pm-10:27 am

2 stops17h 57m

$294

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 3/7

6:33 pm-2:15 pm

2 stops19h 42m

Cartagena Rafael Nunez

Sat 3/14

3:15 pm-12:59 pm

2 stops20h 44m

$294

PittsburghCartagena

PIT - CTG

PITCTG

Pittsburgh

Sat 4/11

7:21 pm-2:04 pm

1 stop19h 43m

Cartagena Rafael Nunez

Sat 4/18

1:25 pm-10:13 am

2 stops19h 48m

$301

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Sun 2/1

7:00 am-2:55 pm

1 stop7h 55m

Medellín Jose Maria Cordova Intl

Thu 2/5

2:25 pm-10:48 pm

1 stop8h 23m

$312

PittsburghMedellín

PIT - MDE

PITMDE

Pittsburgh

Mon 2/2

2:09 pm-10:05 pm

2 stops31h 56m

Medellín Jose Maria Cordova Intl

Thu 2/5

10:45 am-9:47 am

2 stops23h 02m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Pittsburgh to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to South America

What is the cheapest month to book a flight from Pittsburgh to South America?

Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in June is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 8, 2026.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Pittsburgh to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,032 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,901 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,097 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
JetBlue
7.2
Good
2,891 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Spirit Airlines
6.3
Okay
8,289 reviews
Delta
7.9
Good
8,032 reviews

Crew

8.5

Overall

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Pittsburgh to South America?

    Most people fly from Pittsburgh (PIT) if they book a flight from Pittsburgh to South America. Pittsburgh is conveniently located just 13.5 mi from Pittsburgh’s city center.

  • How long is the flight from Pittsburgh to South America?

    Departing from Pittsburgh to South America will take you 7h 55m. Airlines will cover a distance of 2389 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Pittsburgh to South America one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from JetBlue and American Airlines, as they are both options that can get you from Pittsburgh to South America for a low price.

  • What are the most popular routes from Pittsburgh to South America?

    While some choose either Pittsburgh - Lima J Chavez Intl or Pittsburgh - Cartagena Rafael Nunez, Pittsburgh - Medellín Jose Maria Cordova Intl is the most popular route from Pittsburgh to South America.

  • Can I find deals for flights from Pittsburgh to South America that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to South America.

  • Can I find deals for business class flights from Pittsburgh to South America?

    Yes. Cheapflights offers flight deals from Pittsburgh to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to South America?

    Currently, October is the cheapest month in which you can book a flight from Pittsburgh to South America (average of $261). Flying from Pittsburgh to South America in June is currently the most expensive (average of $523). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Pittsburgh to South America

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Miami flights
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Fort Lauderdale flights
LaGuardia to Miami flights
Newark to West Palm Beach flights
Newark to Fort Lauderdale flights
John F Kennedy Intl to Cancún flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to West Palm Beach flights
John F Kennedy Intl to Orlando flights
Newark to Cancún flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Newark to Las Vegas flights
Dulles Intl to Miami flights
John F Kennedy Intl to Dallas/Fort Worth flights
Newark to Orlando flights
John F Kennedy Intl to Luis Munoz Marin Intl flights
Newark to Mexico City flights
John F Kennedy Intl to Tampa flights
Newark to Luis Munoz Marin Intl flights
LaGuardia to West Palm Beach flights
LaGuardia to Tampa flights
LaGuardia to Dallas/Fort Worth flights
John F Kennedy Intl to Haneda flights
LaGuardia to Cancún flights
John F Kennedy Intl to Mexico City flights
Newark to Tampa flights
LaGuardia to Orlando flights
John F Kennedy Intl to Heathrow flights
John F Kennedy Intl to Sky Harbor Intl flights
Dulles Intl to Cancún flights
John F Kennedy Intl to Charles de Gaulle flights
Newark to Haneda flights
Dulles Intl to Orlando flights
Newark to Heathrow flights
Newark to Sky Harbor Intl flights
Reagan-National to Miami flights
Newark to Los Angeles flights
Dulles Intl to Las Vegas flights
Newark to Narita flights
Philadelphia to Orlando flights
John F Kennedy Intl to New Orleans flights
LaGuardia to Hobby flights
Philadelphia to Miami flights
Newark to Charles de Gaulle flights
Dulles Intl to Dallas/Fort Worth flights
LaGuardia to Los Angeles flights
Philadelphia to Fort Lauderdale flights
LaGuardia to New Orleans flights

Top 7 airlines flying from Pittsburgh to South America

Discover the top 7 airlines that operate flights from Pittsburgh to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$265Average$375FlexibilityNo cancel feeOn-time65%
JetBlueCheapest$333Average$373FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$347Average$925FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$458Average$706FlexibilityNo cancel feeOn-time71%
DeltaCheapest$501Average$856FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$594Average$970FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$712Average$947FlexibilityNo cancel feeOn-time70%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.