How long is the flight from Minneapolis to South America?

There are many flights that can get you from Minneapolis to South America in 8h. Fly via Spirit Airlines, Copa Airlines, or Delta to get the fastest option. Airlines will cover a distance of 2600 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Minneapolis to South America?

The most popular flight routes from Minneapolis to South America are Minneapolis St Paul - Lima J Chavez Intl, Minneapolis St Paul - Bogotá El Dorado and Minneapolis St Paul - Buenos Aires Ministro Pistarini.

What are the most popular airlines that fly from Minneapolis to South America?

The most popular airlines flying from Minneapolis to South America are Delta, American Airlines and LATAM Airlines. Something to consider prior to booking your flight.

What airport do you fly from for flights from Minneapolis to South America?

Minneapolis St Paul (MSP) is the airport you will fly out of if you book a flight from Minneapolis to South America. It is only a 7.3 mi journey to Minneapolis St Paul (MSP) from Minneapolis’s city center.

Can I find deals for flights from Minneapolis to South America that include hotel bookings?

Yes. In addition to deals on Minneapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Minneapolis to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South America.

Can I find deals for business class flights from Minneapolis to South America?

Yes. Cheapflights offers flight deals from Minneapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$164+ Cheap Flights from Minneapolis to South America

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Cheap flight deals from Minneapolis to South America

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$413 (Kiwi.com)
One-way from	$164 (Kiwi.com)
Popular in	December
Cheapest in	November

Provider with most accurate pricing for Minneapolis St Paul-Sao Paulo (SAO) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Minneapolis St Paul-Sao Paulo (SAO) flights.

Search Deals

From Minneapolis St Paul to South America

Search Deals

One-way flight from Minneapolis St Paul to South America

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($48 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($32 potential savings vs. average RT price).

Search Deals

Find flight deals from Minneapolis to South America

Cheapest flights from Minneapolis to South America
Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

Thu 11/136:36 amMSP - BOG

1 stop30h 34mMultiple Airlines

Wed 11/193:15 pmBOG - MSP

2 stops30h 59mMultiple Airlines

Deal found 10/13

$413

Thu 11/131:05 pmMSP - BOG

2 stops24h 05mSpirit Airlines

Wed 11/193:15 pmBOG - MSP

2 stops22h 35mSpirit Airlines

Deal found 10/13

$429

Sun 11/161:42 pmMSP - BOG

1 stop22h 18mMultiple Airlines

Sun 11/231:55 pmBOG - MSP

1 stop25h 47mMultiple Airlines

Deal found 10/14

$433

Thu 11/135:15 pmMSP - CTG

2 stops43h 00mMultiple Airlines

Wed 11/192:20 pmCTG - MSP

1 stop25h 40mMultiple Airlines

Deal found 10/13

$434

Sat 10/255:45 amMSP - CTG

2 stops30h 40mSpirit Airlines

Sat 11/11:32 pmCTG - MSP

2 stops23h 28mSpirit Airlines

Deal found 10/14

$443

Sun 12/76:30 amMSP - BOG

1 stop29h 22mMultiple Airlines

Mon 12/151:47 pmBOG - MSP

2 stops34h 37mMultiple Airlines

Deal found 10/13

$447

Fri 11/283:36 pmMSP - BOG

1 stop20h 24mMultiple Airlines

Fri 12/51:47 pmBOG - MSP

2 stops34h 37mMultiple Airlines

Deal found 10/14

$449

Sat 11/15:45 amMSP - BOG

2 stops32h 25mSpirit Airlines

Sat 11/83:15 pmBOG - MSP

2 stops21h 45mSpirit Airlines

Deal found 10/14

$450

Mon 11/31:05 pmMSP - BOG

2 stops24h 05mMultiple Airlines

Mon 11/101:55 pmBOG - MSP

1 stop25h 21mMultiple Airlines

Deal found 10/14

$472

Thu 11/131:05 pmMSP - CTG

2 stops23h 10mSpirit Airlines

Wed 11/192:20 pmCTG - MSP

2 stops23h 30mSpirit Airlines

Deal found 10/13

$475

Sat 11/226:24 amMSP - MDE

1 stop30h 39mMultiple Airlines

Thu 11/273:14 pmMDE - MSP

2 stops22h 28mMultiple Airlines

Deal found 10/14

$500

Sun 10/264:18 pmMSP - MDE

2 stops20h 46mMultiple Airlines

Wed 10/292:22 pmMDE - MSP

2 stops23h 20mMultiple Airlines

Deal found 10/12

$503

Best flights from Minneapolis to South America
Discover carefully curated flight deals from Minneapolis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2025.

Sat 10/255:45 amMSP - CTG

2 stops30h 40mSpirit Airlines

Sat 11/11:32 pmCTG - MSP

2 stops23h 28mSpirit Airlines

Deal found 10/14

$443

Tue 11/412:30 pmMSP - MDE

1 stop24h 25mMultiple Airlines

Tue 11/182:57 pmMDE - MSP

1 stop24h 32mMultiple Airlines

Deal found 10/13

$539

Sat 2/148:15 amMSP - BOG

2 stops15h 30mCopa Airlines

Fri 2/206:08 pmBOG - MSP

2 stops26h 43mCopa Airlines

Deal found 10/12

$579

Wed 1/215:15 amMSP - CTG

1 stop8h 00mDelta

Wed 1/285:05 amCTG - MSP

2 stops17h 24mDelta

Deal found 10/13

$614

Wed 1/214:08 pmMSP - CTG

2 stops20h 22mAmerican Airlines

Wed 1/282:30 pmCTG - MSP

2 stops20h 55mAmerican Airlines

Deal found 10/13

$616

Sun 2/17:35 amMSP - MDE

1 stop13h 30mUnited Airlines

Wed 2/1110:45 amMDE - MSP

1 stop13h 14mUnited Airlines

Deal found 10/13

$636

Sun 1/2512:00 pmMSP - SCL

1 stop21h 15mAir Canada

Sun 2/88:35 amSCL - MSP

2 stops39h 44mAir Canada

Deal found 10/12

$778

Wed 12/318:50 amMSP - UIO

1 stop19h 27mLATAM Airlines

Thu 1/2911:45 pmUIO - MSP

1 stop11h 45mLATAM Airlines

Deal found 10/13

$780

Sun 1/184:42 pmMSP - MDE

2 stops17h 21mMultiple Airlines

Tue 1/272:54 pmMDE - MSP

1 stop25h 48mMultiple Airlines

Deal found 10/13

$584

Sun 1/185:33 pmMSP - MDE

2 stops19h 36mAmerican Airlines

Tue 1/273:10 pmMDE - MSP

2 stops20h 40mAmerican Airlines

Deal found 10/13

$631

Thu 3/57:15 amMSP - BOG

1 stop20h 55mUnited Airlines

Fri 3/131:30 amBOG - MSP

2 stops18h 10mUnited Airlines

Deal found 10/13

$644

Sun 10/264:18 pmMSP - MDE

3 stops29h 37mMultiple Airlines

Tue 10/281:16 amMDE - MSP

2 stops15h 21mMultiple Airlines

Deal found 10/12

$598

Tue 11/48:00 amMSP - BOG

2 stops24h 25mCopa Airlines

Wed 11/129:55 amBOG - MSP

2 stops25h 52mCopa Airlines

Deal found 10/13

$675

Thu 3/58:15 pmMSP - BOG

1 stop17h 20mDelta

Sat 3/142:55 pmBOG - MSP

1 stop18h 19mDelta

Deal found 10/13

$678

Sun 4/55:54 pmMSP - CTG

2 stops38h 47mUnited Airlines

Mon 4/139:42 amCTG - MSP

2 stops37h 23mUnited Airlines

Deal found 10/12

$645

Sat 1/3111:40 amMSP - BOG

1 stop10h 50mAmerican Airlines

Sat 2/78:00 amBOG - MSP

1 stop16h 59mAmerican Airlines

Deal found 10/14

$648

Sat 11/158:00 amMSP - CTG

2 stops23h 06mCopa Airlines

Mon 12/1512:03 pmCTG - MSP

2 stops23h 44mCopa Airlines

Deal found 10/12

$677

Fri 3/136:05 pmMSP - BOG

1 stop19h 30mDelta

Fri 3/272:55 pmBOG - MSP

1 stop18h 19mDelta

Deal found 10/13

$678

Wed 1/142:05 pmMSP - MDE

1 stop31h 00mUnited Airlines

Fri 1/2310:45 amMDE - MSP

1 stop13h 22mUnited Airlines

Deal found 10/13

$647

Thu 1/156:12 amMSP - MDE

1 stop15h 03mMultiple Airlines

Fri 1/231:51 amMDE - MSP

2 stops13h 27mMultiple Airlines

Deal found 10/13

$667

Thu 11/138:00 amMSP - BOG

2 stops25h 10mCopa Airlines

Tue 11/184:45 amBOG - MSP

2 stops31h 02mCopa Airlines

Deal found 10/13

$678

Tue 12/306:00 amMSP - MDE

2 stops14h 10mAmerican Airlines

Wed 1/71:25 amMDE - MSP

2 stops15h 47mAmerican Airlines

Deal found 10/13

$681

Tue 3/38:15 pmMSP - CTG

1 stop17h 00mDelta

Fri 3/63:30 pmCTG - MSP

1 stop18h 44mDelta

Deal found 10/13

$691

Fri 3/205:59 pmMSP - BOG

1 stop11h 11mUnited Airlines

Thu 4/212:14 amBOG - MSP

1 stop12h 38mUnited Airlines

Deal found 10/13

$678

Tue 11/119:00 amMSP - LIM

1 stop12h 15mMultiple Airlines

Mon 11/172:15 amLIM - MSP

2 stops37h 10mMultiple Airlines

Deal found 10/14

$680

Sat 12/134:45 pmMSP - CTG

2 stops29h 26mDelta

Wed 1/143:30 pmCTG - MSP

1 stop18h 44mDelta

Deal found 10/12

$706

Fri 3/131:53 pmMSP - BOG

1 stop15h 17mUnited Airlines

Thu 3/191:30 amBOG - MSP

1 stop11h 18mUnited Airlines

Deal found 10/14

$678

Tue 1/2012:00 pmMSP - SDU

2 stops23h 10mAir Canada

Thu 2/511:20 amSDU - MSP

2 stops36h 59mAir Canada

Deal found 10/12

$1,036

Sun 12/285:48 amMSP - UIO

1 stop14h 10mAmerican Airlines

Fri 1/1612:49 amUIO - MSP

2 stops15h 07mAmerican Airlines

Deal found 10/12

$779

Tue 3/38:15 pmMSP - CTG

1 stop17h 00mDelta

Thu 3/53:30 pmCTG - MSP

1 stop18h 44mDelta

Deal found 10/12

$716

Last-minute flights from Minneapolis to South America
Discover last-minute flight deals from Minneapolis to South America. Data last updated October 14, 2025 and is based on user searches.

Sat 10/255:45 amMSP - CTG

2 stops30h 40mSpirit Airlines

Sat 11/11:32 pmCTG - MSP

2 stops23h 28mSpirit Airlines

Deal found 10/14

$443

Sun 10/266:30 amMSP - MDE

1 stop26h 30mMultiple Airlines

Wed 10/292:22 pmMDE - MSP

2 stops33h 05mMultiple Airlines

Deal found 10/12

$503

Sat 11/15:45 amMSP - BOG

2 stops32h 25mSpirit Airlines

Sat 11/83:15 pmBOG - MSP

2 stops21h 45mSpirit Airlines

Deal found 10/14

$450

Mon 11/31:05 pmMSP - BOG

2 stops24h 05mMultiple Airlines

Mon 11/101:55 pmBOG - MSP

1 stop25h 21mMultiple Airlines

Deal found 10/14

$472

Tue 11/412:30 pmMSP - MDE

1 stop24h 25mMultiple Airlines

Tue 11/1810:00 pmMDE - MSP

2 stops42h 00mMultiple Airlines

Deal found 10/13

$523

Thu 11/136:36 amMSP - BOG

1 stop30h 34mMultiple Airlines

Wed 11/193:15 pmBOG - MSP

2 stops30h 59mMultiple Airlines

Deal found 10/13

$413

Thu 11/131:05 pmMSP - BOG

2 stops24h 05mSpirit Airlines

Wed 11/193:15 pmBOG - MSP

2 stops22h 35mSpirit Airlines

Deal found 10/13

$429

Thu 11/135:15 pmMSP - CTG

2 stops43h 00mMultiple Airlines

Wed 11/192:20 pmCTG - MSP

1 stop25h 40mMultiple Airlines

Deal found 10/13

$434

Thu 11/131:05 pmMSP - CTG

2 stops23h 10mSpirit Airlines

Wed 11/192:20 pmCTG - MSP

2 stops23h 30mSpirit Airlines

Deal found 10/13

$475

Sun 11/161:42 pmMSP - BOG

1 stop22h 18mMultiple Airlines

Sun 11/231:55 pmBOG - MSP

1 stop25h 47mMultiple Airlines

Deal found 10/14

$433

Sat 11/226:24 amMSP - MDE

1 stop30h 39mMultiple Airlines

Thu 11/273:14 pmMDE - MSP

2 stops22h 28mMultiple Airlines

Deal found 10/14

$500

Fri 11/283:36 pmMSP - BOG

1 stop20h 24mMultiple Airlines

Fri 12/51:47 pmBOG - MSP

2 stops34h 37mMultiple Airlines

Deal found 10/14

$449

One-way flights from Minneapolis to South America
Search for one-way flight options from Minneapolis to South America. Find affordable one-way fares based on user searches. Data last updated October 14, 2025.

Sat 11/110:15 amMSP - CTG

3 stops27h 00mMultiple Airlines

Deal found 10/12

$164

Tue 12/98:00 amMSP - BOG

3 stops39h 55mMultiple Airlines

Deal found 10/14

$171

Sun 12/76:30 amMSP - BOG

1 stop29h 22mMultiple Airlines

Deal found 10/14

$179

Tue 12/98:00 amMSP - CTG

3 stops28h 20mMultiple Airlines

Deal found 10/13

$181

Sat 12/66:45 amMSP - BOG

3 stops30h 24mMultiple Airlines

Deal found 10/14

$196

Fri 12/58:18 amMSP - BOG

2 stops39h 37mMultiple Airlines

Deal found 10/14

$197

Wed 12/38:00 amMSP - BOG

3 stops39h 55mMultiple Airlines

Deal found 10/13

$204

Thu 12/46:12 amMSP - BOG

1 stop17h 43mMultiple Airlines

Deal found 10/14

$206

Fri 10/315:45 amMSP - CTG

2 stops30h 40mSpirit Airlines

Deal found 10/12

$208

Wed 12/108:00 amMSP - BOG

3 stops28h 29mMultiple Airlines

Deal found 10/14

$209

Mon 12/87:06 amMSP - BOG

2 stops16h 49mMultiple Airlines

Deal found 10/14

$211

Wed 12/317:18 amMSP - MDE

1 stop16h 56mMultiple Airlines

Deal found 10/12

$218

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

Sat 10/25

5:45 am-12:25 pm

2 stops30h 40m

Cartagena Rafael Nunez

Sat 11/1

1:32 pm-1:00 pm

2 stops23h 28m

$443

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Tue 11/4

12:30 pm-1:55 pm

1 stop24h 25m

Medellín Jose Maria Cordova Intl

Tue 11/18

2:57 pm-2:29 pm

1 stop24h 32m

$539

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Sat 2/14

8:15 am-12:45 am

2 stops15h 30m

Bogotá El Dorado

Fri 2/20

6:08 pm-7:51 pm

2 stops26h 43m

$579

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 1/18

4:42 pm-11:03 am

2 stops17h 21m

Medellín Jose Maria Cordova Intl

Tue 1/27

2:54 pm-3:42 pm

1 stop25h 48m

$584

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 10/26

4:18 pm-9:55 pm

3 stops29h 37m

Medellín Jose Maria Cordova Intl

Tue 10/28

1:16 am-4:37 pm

2 stops15h 21m

$598

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

Wed 1/21

5:15 am-2:15 pm

1 stop8h 00m

Cartagena Rafael Nunez

Wed 1/28

5:05 am-9:29 pm

2 stops17h 24m

$614

MinneapolisCartagena

MSP - CTG

MSPCTG

Minneapolis St Paul

Wed 1/21

4:08 pm-1:30 pm

2 stops20h 22m

Cartagena Rafael Nunez

Wed 1/28

2:30 pm-10:25 am

2 stops20h 55m

$616

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 1/18

5:33 pm-2:09 pm

2 stops19h 36m

Medellín Jose Maria Cordova Intl

Tue 1/27

3:10 pm-10:50 am

2 stops20h 40m

$631

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 2/1

7:35 am-10:05 pm

1 stop13h 30m

Medellín Jose Maria Cordova Intl

Wed 2/11

10:45 am-10:59 pm

1 stop13h 14m

$636

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Thu 3/5

7:15 am-5:10 am

1 stop20h 55m

Bogotá El Dorado

Fri 3/13

1:30 am-7:40 pm

2 stops18h 10m

$644

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/12

Showing 1-10 of 60 results

...

Best time to book a flight from Minneapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Minneapolis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South America

What is the cheapest month to book a flight from Minneapolis to South America?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to South America (average of $212). Flying from Minneapolis to South America in June is currently the most expensive (average of $612). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SA?

When flying from Minneapolis to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 26% versus a flight in the morning.

What is the cheapest day to fly from Minneapolis to South America?

Travelers seeking maximum savings on their Minneapolis to South America flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Read through reviews of airlines operating flights from Minneapolis to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Delta

8.0

Very good

7,972 reviews

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

LATAM Airlines

7.5

Good

1,865 reviews

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

United Airlines

7.4

Good

8,975 reviews

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

American Airlines

7.2

Good

11,043 reviews

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Air Canada

7.1

Good

10,291 reviews

Delta

8.0

Very good

7,972 reviews

Reviews

1 / 20

8.0

Excellent

Matthew,Oct 2025

GSP - ATL

Related info for your journey

What airport do you fly from for flights from Minneapolis to South America?
Minneapolis St Paul (MSP) is the airport you will fly out of if you book a flight from Minneapolis to South America. It is only a 7.3 mi journey to Minneapolis St Paul (MSP) from Minneapolis’s city center.
How long is the flight from Minneapolis to South America?
There are many flights that can get you from Minneapolis to South America in 8h. Fly via Spirit Airlines, Copa Airlines, or Delta to get the fastest option. Airlines will cover a distance of 2600 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the most popular routes from Minneapolis to South America?
The most popular flight routes from Minneapolis to South America are Minneapolis St Paul - Lima J Chavez Intl, Minneapolis St Paul - Bogotá El Dorado and Minneapolis St Paul - Buenos Aires Ministro Pistarini.
Can I find deals for flights from Minneapolis to South America that include hotel bookings?
Yes. In addition to deals on Minneapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Minneapolis to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South America.
Can I find deals for business class flights from Minneapolis to South America?
Yes. Cheapflights offers flight deals from Minneapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Minneapolis to South America?
Currently, September is the cheapest month in which you can book a flight from Minneapolis to South America (average of $212). Flying from Minneapolis to South America in June is currently the most expensive (average of $612). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 9 airlines flying from Minneapolis to South America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$239	Average$1,092	FlexibilityNo cancel fee	On-timeN/A
Sky Airlines Peru	Cheapest$292	Average$348	FlexibilityNo cancel fee	On-timeN/A
Spirit Airlines	Cheapest$354	Average$471	FlexibilityNo cancel fee	On-time65%
United Airlines	Cheapest$410	Average$1,181	FlexibilityNo cancel fee	On-time69%
Avianca	Cheapest$536	Average$695	FlexibilityNo cancel fee	On-time71%
American Airlines	Cheapest$574	Average$1,065	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$603	Average$965	FlexibilityNo cancel fee	On-time81%
Copa Airlines	Cheapest$630	Average$812	FlexibilityNo cancel fee	On-time70%
Air Canada	Cheapest$773	Average$1,100	FlexibilityNo cancel fee	On-time67%

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$164+ Cheap flights from Minneapolis (MSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Minneapolis to South America with Cheapflights

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Cheap flight deals from Minneapolis to South America

Keep the following information in mind while searching for Minneapolis to South America flight deals. Data was last updated October 14, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Find flight deals from Minneapolis to South America

Cheapest flights from Minneapolis to South AmericaExplore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Best time to book a flight from Minneapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Minneapolis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South America

What is the cheapest month to book a flight from Minneapolis to South America?

What is the cheapest time of day to fly from MSP to SA?

Find hourly flight availability from Minneapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 14, 2025.

What is the cheapest day to fly from Minneapolis to South America?

Use this chart to determine the cheapest time to fly round-trip from Minneapolis to South America. Price data was last updated on December 16, 2024.

Reviews of airlines servicing South America

Read through reviews of airlines operating flights from Minneapolis to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Minneapolis to South America?

How long is the flight from Minneapolis to South America?

What are the most popular routes from Minneapolis to South America?

Can I find deals for flights from Minneapolis to South America that include hotel bookings?

How can I find direct flights from Minneapolis to South America?

Can I find deals for business class flights from Minneapolis to South America?

What is the cheapest month to book a flight from Minneapolis to South America?

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Alternative routes for Minneapolis to South America

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Top 9 airlines flying from Minneapolis to South America

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Cheapest flights from Minneapolis to South America
Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.