South America

$179+ Cheap flights from Minneapolis (MSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — BOG
May 21 — May 281
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Cheap flight deals from Minneapolis to South America

Cheapest flights from Minneapolis to South America
Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:22 pm
MSP
-
MDE
2 stops22h 38m
Multiple Airlines
Fri 5/221:55 pm
MDE
-
MSP
1 stop21h 37m
Multiple Airlines
Deal found 4/17$493
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:40 pm
MSP
-
MDE
1 stop22h 20m
Multiple Airlines
Mon 5/181:55 pm
MDE
-
MSP
2 stops26h 07m
Multiple Airlines
Deal found 4/18$519
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
MSP
-
MDE
1 stop26h 15m
Multiple Airlines
Wed 5/2711:10 pm
MDE
-
MSP
2 stops22h 46m
Multiple Airlines
Deal found 4/16$524
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
MSP
-
MDE
1 stop26h 15m
Multiple Airlines
Sat 5/231:55 pm
MDE
-
MSP
1 stop21h 07m
Multiple Airlines
Deal found 4/16$525
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:49 am
MSP
-
BOG
1 stop10h 46m
Multiple Airlines
Sat 5/92:08 pm
BOG
-
MSP
1 stop21h 30m
Multiple Airlines
Deal found 4/19$533
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
MSP
-
MDE
1 stop26h 15m
Multiple Airlines
Fri 5/291:55 pm
MDE
-
MSP
2 stops19h 24m
Multiple Airlines
Deal found 4/16$538
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:40 pm
MSP
-
MDE
1 stop22h 20m
Multiple Airlines
Fri 5/221:55 pm
MDE
-
MSP
1 stop21h 37m
Multiple Airlines
Deal found 4/17$545
This Mytrip deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/316:35 am
MSP
-
GYE
2 stops16h 29m
Multiple Airlines
Sun 6/711:59 pm
GYE
-
MSP
2 stops19h 49m
Multiple Airlines
Deal found 4/16$545
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:22 pm
MSP
-
MDE
2 stops22h 38m
Multiple Airlines
Sat 5/301:55 pm
MDE
-
MSP
1 stop32h 06m
Multiple Airlines
Deal found 4/17$546
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:34 am
MSP
-
MDE
1 stop26h 26m
Multiple Airlines
Sat 5/231:55 pm
MDE
-
MSP
1 stop21h 07m
Multiple Airlines
Deal found 4/16$551
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:45 am
MSP
-
MDE
1 stop26h 15m
Multiple Airlines
Sun 5/245:40 am
MDE
-
MSP
2 stops13h 32m
Multiple Airlines
Deal found 4/16$553
This Expedia deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:10 pm
MSP
-
LIM
1 stop12h 05m
Air Canada
Sat 11/78:00 am
LIM
-
MSP
1 stop13h 10m
Air Canada
Deal found 4/20$572

Find flight deals from Minneapolis to South America

Keep the following information in mind while searching for Minneapolis to South America flight deals. Data was last updated April 21, 2026.

Round-trip from

$493
(Kiwi.com)

One-way from

$179
(Kiwi.com)

Popular in

November

Cheapest in

August

Average price

$718
From Minneapolis St Paul to South America
One-way flight from Minneapolis St Paul to South America
Highest demand for flights based on searches. 4% potential increase in price ($32 potential increase over avg. RT price).
Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Mon 9/14

1:10 pm-8:55 am

2 stops19h 45m

Guayaquil Jose Joaquin de Olmedo

Wed 9/30

10:05 am-8:38 pm

2 stops34h 33m

$647

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Mon 9/7

1:10 pm-4:15 am

1 stop15h 05m

Bogotá El Dorado

Thu 9/10

2:00 pm-8:38 pm

1 stop30h 38m

$663

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

Tue 9/1

3:55 pm-2:05 pm

1 stop22h 10m

Bogotá El Dorado

Thu 9/10

2:00 pm-8:38 pm

1 stop30h 38m

$668

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Wed 5/20

4:57 pm-1:00 pm

2 stops44h 03m

Medellín Jose Maria Cordova Intl

Mon 5/25

1:55 pm-3:03 pm

1 stop25h 08m

$673

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Thu 8/20

7:36 am-9:10 pm

1 stop13h 34m

Medellín Jose Maria Cordova Intl

Thu 8/27

9:45 am-11:19 pm

1 stop13h 34m

$680

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Sun 6/28

9:52 am-8:15 am

2 stops22h 23m

Medellín Jose Maria Cordova Intl

Wed 7/8

9:15 am-8:46 am

2 stops23h 31m

$684

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

Fri 5/22

2:00 pm-10:20 am

2 stops20h 20m

Medellín Jose Maria Cordova Intl

Wed 5/27

10:45 pm-9:56 pm

2 stops23h 11m

$684

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Mon 9/14

7:55 pm-7:00 am

1 stop11h 05m

Guayaquil Jose Joaquin de Olmedo

Mon 11/23

5:00 pm-9:40 am

1 stop17h 40m

$687

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Mon 9/14

7:55 pm-7:00 am

1 stop11h 05m

Guayaquil Jose Joaquin de Olmedo

Wed 9/30

4:05 pm-1:34 pm

1 stop21h 29m

$687

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

Thu 6/11

6:02 am-10:37 pm

2 stops16h 35m

Guayaquil Jose Joaquin de Olmedo

Thu 6/25

2:31 pm-12:53 pm

2 stops22h 22m

$692

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/16

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Minneapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South America

What is the cheapest month to book a flight from Minneapolis to South America?

Currently, February is the cheapest month in which you can book a flight from Minneapolis to South America (average of $157). Flying from Minneapolis to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 21, 2026.
Read through reviews of airlines operating flights from Minneapolis to South America, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Comfort

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Minneapolis to South America?

    Minneapolis St Paul (MSP) is the airport you will fly out of if you book a flight from Minneapolis to South America. It is only a 7.3 mi journey to Minneapolis St Paul (MSP) from Minneapolis’s city center.

  • How long is the flight from Minneapolis to South America?

    There are many flights that can get you from Minneapolis to South America in 11h 05m. Fly via Avianca, Delta, or Copa Airlines to get the fastest option. Airlines will cover a distance of 3350 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Minneapolis to South America one-way?

    The cheapest airlines for a one-way flight from Minneapolis to South America are Spirit Airlines ($155), Copa Airlines ($277), and American Airlines ($342).

  • What are the most popular routes from Minneapolis to South America?

  • Can I find deals for flights from Minneapolis to South America that include hotel bookings?

    Yes. In addition to deals on Minneapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South America.

  • Can I find deals for business class flights from Minneapolis to South America?

    Yes. Cheapflights offers flight deals from Minneapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to South America?

    Currently, February is the cheapest month in which you can book a flight from Minneapolis to South America (average of $157). Flying from Minneapolis to South America in June is currently the most expensive (average of $381). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Minneapolis to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 8 airlines flying from Minneapolis to South America

Discover the top 8 airlines that operate flights from Minneapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
Sun Country AirCheapest$166Average$258FlexibilityNo cancel feeOn-time83%
DeltaCheapest$239Average$1,159FlexibilityNo cancel feeOn-timeN/A
Sky Airlines PeruCheapest$292Average$322FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$392Average$1,041FlexibilityNo cancel feeOn-time69%
Copa AirlinesCheapest$397Average$808FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$603Average$1,126FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$626Average$968FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$698Average$738FlexibilityNo cancel feeOn-time67%

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