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South America

$176+ Cheap flights from Minneapolis (MSP) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — BOG
dec. 29 — jan. 51
ma 12/29
ma 1/5
1 adult, Economy
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Cheap flight deals from Minneapolis to South America

Keep the following information in mind while searching for Minneapolis to South America flight deals. Data was last updated november 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$375
(Mytrip)

One-way from

$152
(Mytrip)

Popular in

December

Cheapest in

September
Provider with most accurate pricing for Minneapolis St Paul-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Minneapolis St Paul-Sao Paulo (SAO) flights.
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From Minneapolis St Paul to South America
Search Deals
One-way flight from Minneapolis St Paul to South America
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($174 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($41 potential savings vs. average RT price).
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Find flight deals from Minneapolis to South America

Cheapest flights from Minneapolis to South America
Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on november 29, 2025.

This Mytrip deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 12/284:18 pmMSP - MDE
2 stops20h 39mMultiple Airlines
wo 1/282:50 pmMDE - MSP
2 stops25h 22mMultiple Airlines
Deal found 11/29$590
This Mytrip deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 12/156:54 amMSP - BOG
2 stops28h 58mMultiple Airlines
do 1/153:06 pmBOG - MSP
2 stops21h 05mMultiple Airlines
Deal found 11/28$648
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/254:48 pmMSP - BOG
2 stops31h 24mMultiple Airlines
wo 1/213:06 pmBOG - MSP
1 stop25h 06mMultiple Airlines
Deal found 11/29$652
This Kiwi.com deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
di 12/166:12 amMSP - BOG
1 stop29h 40mMultiple Airlines
vr 1/161:45 pmBOG - MSP
2 stops34h 33mMultiple Airlines
Deal found 11/27$654
This Mytrip deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/188:12 amMSP - GYE
2 stops14h 41mMultiple Airlines
wo 12/3112:49 amGYE - MSP
2 stops15h 38mMultiple Airlines
Deal found 11/28$668
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 12/76:24 amMSP - MDE
1 stop17h 45mMultiple Airlines
wo 12/312:25 amMDE - MSP
2 stops36h 37mMultiple Airlines
Deal found 11/29$669
This Copa Airlines deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 12/19:55 amMSP - BOG
2 stops22h 30mCopa Airlines
vr 12/54:45 amBOG - MSP
2 stops15h 55mCopa Airlines
Deal found 11/28$688
This Mytrip deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/257:48 amMSP - SCL
1 stop16h 47mMultiple Airlines
wo 3/49:05 pmSCL - MSP
2 stops21h 19mMultiple Airlines
Deal found 11/28$692
This Mytrip deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 12/144:24 pmMSP - LIM
3 stops27h 21mMultiple Airlines
wo 12/1711:37 pmLIM - MSP
1 stop16h 29mMultiple Airlines
Deal found 11/26$697
This Mytrip deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/47:36 amMSP - LIM
2 stops13h 59mMultiple Airlines
di 2/311:33 pmLIM - MSP
2 stops15h 45mMultiple Airlines
Deal found 11/27$701
This Kiwi.com deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 12/56:12 amMSP - GYE
1 stop16h 31mMultiple Airlines
za 12/612:49 amGYE - MSP
2 stops31h 47mMultiple Airlines
Deal found 11/28$704
This Mytrip deal was found by Cheapflights users on 11/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/257:48 amMSP - SCL
1 stop16h 47mMultiple Airlines
ma 3/212:35 pmSCL - MSP
2 stops30h 37mMultiple Airlines
Deal found 11/28$709

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated november 29, 2025.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.

Fly from

Minneapolis

Fly to

South America

Route

Depart

Return

Price

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

ma 1/12

7:36 am-12:21 am

2 stops15h 45m

Guayaquil Jose Joaquin de Olmedo

di 1/20

1:26 am-2:18 pm

2 stops13h 52m

$460

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

di 2/10

3:00 pm-11:55 pm

2 stops31h 55m

Guayaquil Jose Joaquin de Olmedo

zo 2/22

12:59 am-9:41 pm

2 stops21h 42m

$471

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

vr 1/23

3:00 pm-9:00 am

1 stop17h 00m

Medellín Jose Maria Cordova Intl

za 1/31

3:15 pm-10:31 am

2 stops20h 16m

$530

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

zo 1/18

4:54 pm-12:21 am

3 stops30h 27m

Guayaquil Jose Joaquin de Olmedo

do 1/29

1:26 am-11:11 pm

2 stops22h 45m

$532

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

di 1/20

7:36 am-12:21 am

2 stops15h 45m

Guayaquil Jose Joaquin de Olmedo

do 2/19

12:59 am-10:27 pm

2 stops22h 28m

$537

MinneapolisGuayaquil

MSP - GYE

MSPGYE

Minneapolis St Paul

zo 1/11

4:42 pm-12:21 am

3 stops30h 39m

Guayaquil Jose Joaquin de Olmedo

za 1/17

1:26 am-10:06 pm

3 stops21h 40m

$538

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

di 1/13

9:55 am-9:25 am

2 stops22h 30m

Bogotá El Dorado

ma 1/19

4:45 am-7:27 pm

2 stops15h 42m

$574

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

do 5/7

8:15 am-12:06 am

2 stops15h 51m

Bogotá El Dorado

do 5/21

4:59 am-9:01 pm

2 stops16h 02m

$574

MinneapolisBogotá

MSP - BOG

MSPBOG

Minneapolis St Paul

di 3/3

7:30 am-8:15 pm

1 stop11h 45m

Bogotá El Dorado

di 3/17

11:10 pm-4:18 pm

1 stop17h 08m

$592

MinneapolisMedellín

MSP - MDE

MSPMDE

Minneapolis St Paul

do 5/7

8:00 am-9:10 pm

1 stop13h 10m

Medellín Jose Maria Cordova Intl

do 5/21

9:45 am-11:05 pm

1 stop13h 20m

$626

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/28

Showing 1-10 of 60 results
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Best time to book a flight from Minneapolis to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to South America

What is the cheapest month to book a flight from Minneapolis to South America?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to South America (average of $212). Flying from Minneapolis to South America in June is currently the most expensive (average of $612). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SA?

Find hourly flight availability from Minneapolis to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated november 29, 2025.

When flying from Minneapolis to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 30% versus a flight in the morning.

What is the cheapest day to fly from Minneapolis to South America?

Use this chart to determine the cheapest time to fly round-trip from Minneapolis to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Minneapolis to South America flight should consider departing on Sunday afternoons when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated november 29, 2025.
Read through reviews of airlines operating flights from Minneapolis to South America, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,056 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Air Canada
7.1
Good
10,484 reviews
Delta
7.9
Good
8,010 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Boarding

8.1

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Minneapolis to South America?

    Minneapolis St Paul (MSP) is the airport you will fly out of if you book a flight from Minneapolis to South America. It is only a 7.3 mi journey to Minneapolis St Paul (MSP) from Minneapolis’s city center.

  • How long is the flight from Minneapolis to South America?

    There are many flights that can get you from Minneapolis to South America in 13h 10m. Fly via Copa Airlines, United Airlines, or Air Canada to get the fastest option. Airlines will cover a distance of 2880 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Minneapolis to South America?

    The most popular flight routes from Minneapolis to South America are Minneapolis St Paul - Quito Mariscal Sucr, Minneapolis St Paul - Rio de Janeiro–Galeão Intl and Minneapolis St Paul - Lima J Chavez Intl.

  • Can I find deals for flights from Minneapolis to South America that include hotel bookings?

    Yes. In addition to deals on Minneapolis to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to South America.

  • Can I find deals for business class flights from Minneapolis to South America?

    Yes. Cheapflights offers flight deals from Minneapolis to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to South America?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to South America (average of $212). Flying from Minneapolis to South America in June is currently the most expensive (average of $612). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Alternative routes for Minneapolis to South America

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Top 9 airlines flying from Minneapolis to South America

Discover the top 9 airlines that operate flights from Minneapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated november 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$239Average$1,099FlexibilityNo cancel feeOn-timeN/A
Sky Airlines PeruCheapest$292Average$329FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$366Average$473FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$527Average$1,092FlexibilityNo cancel feeOn-time69%
AviancaCheapest$536Average$695FlexibilityNo cancel feeOn-time71%
American AirlinesCheapest$574Average$1,061FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$611Average$1,035FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$630Average$812FlexibilityNo cancel feeOn-time70%
Air CanadaCheapest$698Average$977FlexibilityNo cancel feeOn-time67%

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