$225+ Cheap flights from Minneapolis (MSP) to South America
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/15. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — BOG
Nov 13 — Nov 201
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Minneapolis to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minneapolis to South America
Cheapest
Best
Last-minute
One-way
Cheapest flights from Minneapolis to South AmericaExplore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
Explore the most affordable flight options available from Minneapolis to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2026.
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/43:47 pm -
2 stops20h 49m
Tue 12/84:37 pm -
2 stops22h 10m
Deal found 10/11![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop8h 36m
Tue 11/174:37 pm -
2 stops21h 50m
Deal found 10/12![American Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:52 pm -
2 stops22h 43m
Thu 11/194:34 pm -
2 stops16h 55m
Deal found 10/13![American Airlines logo]()
$658
This Mytrip deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:10 am -
2 stops18h 50m
Wed 12/29:45 am -
2 stops30h 37m
Deal found 10/10![Multiple Airlines logo]()
$684
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop8h 34m
Fri 12/42:36 pm -
1 stop9h 59m
Deal found 10/13![American Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:06 pm -
2 stops21h 31m
Tue 12/82:36 pm -
1 stop9h 59m
Deal found 10/10![American Airlines logo]()
$695
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:19 pm -
2 stops23h 17m
Tue 11/102:35 pm -
2 stops18h 47m
Deal found 10/10![American Airlines logo]()
$701
This FlightHub deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:45 am -
2 stops52h 15m
Sat 12/191:10 pm -
1 stop21h 39m
Deal found 10/12![Frontier logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:33 pm -
2 stops44h 18m
Wed 11/252:15 am -
1 stop17h 04m
Deal found 10/14![Multiple Airlines logo]()
$738
This Trip.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
1 stop14h 20m
Wed 12/212:10 am -
1 stop16h 12m
Deal found 10/12![Multiple Airlines logo]()
$743
This Mytrip deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops26h 35m
Wed 11/188:05 pm -
1 stop19h 41m
Deal found 10/11![Multiple Airlines logo]()
$743
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
1 stop9h 30m
Thu 12/311:00 pm -
1 stop16h 58m
Deal found 10/12![Multiple Airlines logo]()
$748
Best flights from Minneapolis to South AmericaDiscover carefully curated flight deals from Minneapolis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
Discover carefully curated flight deals from Minneapolis to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 14, 2026.
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/245:21 pm -
2 stops19h 14m
Sat 1/302:35 pm -
2 stops20h 29m
Deal found 10/11![American Airlines logo]()
$593
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:50 pm -
1 stop10h 20m
Mon 2/88:15 am -
1 stop16h 00m
Deal found 10/13![United Airlines logo]()
$767
This Mytrip deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/286:30 am -
2 stops23h 35m
Sat 12/55:55 am -
3 stops29h 45m
Deal found 10/14![Multiple Airlines logo]()
$791
This Air Canada deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:30 pm -
1 stop12h 40m
Sun 12/138:00 am -
1 stop14h 20m
Deal found 10/14![Air Canada logo]()
$795
This Copa Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
2 stops14h 40m
Tue 11/174:22 am -
2 stops16h 23m
Deal found 10/14![Copa Airlines logo]()
$891
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:05 am -
1 stop13h 20m
Mon 11/1612:55 am -
1 stop13h 53m
Deal found 10/11![Delta logo]()
$928
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:27 pm -
2 stops21h 05m
Fri 12/42:36 pm -
1 stop9h 59m
Deal found 10/13![American Airlines logo]()
$633
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:00 am -
1 stop8h 38m
Mon 2/84:38 pm -
2 stops16h 55m
Deal found 10/14![American Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:51 am -
2 stops12h 14m
Wed 4/712:15 am -
1 stop12h 37m
Deal found 10/9![United Airlines logo]()
$767
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:10 am -
2 stops18h 10m
Fri 12/47:35 pm -
2 stops24h 00m
Deal found 10/12![Multiple Airlines logo]()
$813
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:45 am -
2 stops14h 20m
Mon 1/251:30 am -
1 stop10h 26m
Deal found 10/10![United Airlines logo]()
$771
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:00 am -
2 stops14h 40m
Thu 11/192:47 pm -
2 stops27h 52m
Deal found 10/13![Copa Airlines logo]()
$891
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:35 pm -
2 stops21h 57m
Wed 12/22:36 pm -
1 stop9h 59m
Deal found 10/14![American Airlines logo]()
$744
This Mytrip deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:50 pm -
3 stops27h 15m
Fri 12/411:00 am -
3 stops24h 40m
Deal found 10/13![Multiple Airlines logo]()
$831
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/128:00 am -
1 stop11h 20m
Wed 4/288:30 am -
2 stops27h 34m
Deal found 10/13![United Airlines logo]()
$771
This Travelocity deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/284:30 pm -
1 stop14h 30m
Mon 4/59:35 pm -
1 stop25h 41m
Deal found 10/11![Air Canada logo]()
$981
This Copa Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/288:00 am -
2 stops14h 40m
Sat 12/52:45 pm -
2 stops20h 44m
Deal found 10/14![Copa Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/216:00 am -
1 stop15h 10m
Thu 4/86:30 am -
1 stop16h 22m
Deal found 10/9![American Airlines logo]()
$767
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/95:52 pm -
1 stop10h 18m
Fri 11/208:15 am -
1 stop15h 43m
Deal found 10/10![United Airlines logo]()
$782
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:10 am -
3 stops20h 45m
Thu 12/31:20 pm -
3 stops26h 25m
Deal found 10/12![Multiple Airlines logo]()
$897
This Copa Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:43 am -
2 stops24h 35m
Wed 12/22:45 pm -
2 stops20h 44m
Deal found 10/10![Copa Airlines logo]()
$901
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:30 pm -
2 stops21h 42m
Fri 11/203:11 pm -
2 stops19h 37m
Deal found 10/14![American Airlines logo]()
$773
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:00 am -
2 stops14h 05m
Tue 12/19:45 am -
1 stop30h 55m
Deal found 10/9![United Airlines logo]()
$783
This Air Canada deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/184:30 pm -
2 stops37h 30m
Thu 3/49:30 pm -
1 stop26h 49m
Deal found 10/13![Air Canada logo]()
$1,064
This Copa Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/197:30 am -
2 stops16h 02m
Fri 2/262:24 pm -
2 stops21h 15m
Deal found 10/10![Copa Airlines logo]()
$906
This Mytrip deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 am -
2 stops23h 40m
Tue 11/107:10 am -
3 stops33h 29m
Deal found 10/10![Multiple Airlines logo]()
$918
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:00 am -
1 stop8h 38m
Sun 1/172:35 pm -
2 stops20h 51m
Deal found 10/14![American Airlines logo]()
$783
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:30 am -
1 stop13h 45m
Tue 11/1010:40 am -
1 stop13h 18m
Deal found 10/12![United Airlines logo]()
$784
This Copa Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/139:51 am -
2 stops25h 45m
Fri 1/223:08 am -
2 stops32h 28m
Deal found 10/11![Copa Airlines logo]()
$906
This Mytrip deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:33 pm -
3 stops25h 02m
Mon 11/91:05 pm -
3 stops26h 01m
Deal found 10/10![Multiple Airlines logo]()
$928
Last-minute flights from Minneapolis to South AmericaDiscover last-minute flight deals from Minneapolis to South America. Data last updated October 14, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to South America. Data last updated October 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:19 pm -
2 stops23h 17m
Tue 11/102:35 pm -
2 stops18h 47m
Deal found 10/10![American Airlines logo]()
$701
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/314:19 pm -
2 stops23h 17m
Mon 11/94:37 pm -
2 stops21h 50m
Deal found 10/10![American Airlines logo]()
$738
This Mytrip deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:19 am -
2 stops29h 21m
Sun 11/153:31 am -
3 stops35h 35m
Deal found 10/11![Multiple Airlines logo]()
$749
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop8h 36m
Tue 11/174:37 pm -
2 stops21h 50m
Deal found 10/12![American Airlines logo]()
$647
This Mytrip deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:00 am -
2 stops26h 35m
Wed 11/188:05 pm -
1 stop19h 41m
Deal found 10/11![Multiple Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:52 pm -
2 stops22h 43m
Thu 11/194:34 pm -
2 stops16h 55m
Deal found 10/13![American Airlines logo]()
$658
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:33 pm -
2 stops44h 18m
Wed 11/252:15 am -
1 stop17h 04m
Deal found 10/14![Multiple Airlines logo]()
$738
This Mytrip deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:10 am -
2 stops18h 50m
Wed 12/29:45 am -
2 stops30h 37m
Deal found 10/10![Multiple Airlines logo]()
$684
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:35 pm -
2 stops21h 57m
Wed 12/22:36 pm -
1 stop9h 59m
Deal found 10/10![American Airlines logo]()
$744
This Trip.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
1 stop14h 20m
Wed 12/212:10 am -
1 stop16h 12m
Deal found 10/12![Multiple Airlines logo]()
$743
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:40 am -
1 stop9h 30m
Thu 12/311:00 pm -
1 stop16h 58m
Deal found 10/12![Multiple Airlines logo]()
$748
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:27 pm -
2 stops21h 05m
Fri 12/42:36 pm -
1 stop9h 59m
Deal found 10/13![American Airlines logo]()
$633
One-way flights from Minneapolis to South AmericaSearch for one-way flight options from Minneapolis to South America. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
Search for one-way flight options from Minneapolis to South America. Find affordable one-way fares based on user searches. Data last updated October 14, 2026.
This Priceline deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1510:44 am -
1 stop24h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/255:59 pm -
3 stops40h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:33 pm -
3 stops55h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:59 pm -
3 stops54h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:11 am -
3 stops31h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/78:31 pm -
2 stops38h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/143:28 pm -
3 stops39h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:45 am -
3 stops52h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:01 pm -
3 stops32h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/911:03 am -
3 stops36h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Multiple Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:27 pm -
2 stops21h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![American Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:05 am -
3 stops35h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$335
Find flight deals from Minneapolis to South America
Keep the following information in mind while searching for Minneapolis to South America flight deals. Data was last updated October 14, 2026.
Round-trip from | $516 (FlightHub) |
|---|---|
One-way from | $225 (Priceline) |
Popular in | December |
Cheapest in | June |
Average price | $1,021 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
Use the filters below to find and compare flights from Minneapolis to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisMedellín
MSP Minneapolis St Paul - MDE Medellín Jose Maria Cordova Intl
MSPMDE
Minneapolis St Paul
Tue 12/15
10:44 am-12:00 pm
1 stop24h 16m
Medellín Jose Maria Cordova Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$225
MinneapolisGuayaquil
MSP Minneapolis St Paul - GYE Guayaquil Jose Joaquin de Olmedo
MSPGYE
Minneapolis St Paul
Mon 1/25
5:59 pm-11:22 am
3 stops40h 23m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$237
MinneapolisPereira
MSP Minneapolis St Paul - PEI Pereira Matecana
MSPPEI
Minneapolis St Paul
Sat 11/14
3:28 pm-7:40 am
3 stops39h 12m
Pereira Matecana
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$310
MinneapolisCartagena
MSP Minneapolis St Paul - CTG Cartagena Rafael Nunez
MSPCTG
Minneapolis St Paul
Fri 11/27
3:27 pm-1:32 pm
2 stops21h 05m
Cartagena Rafael Nunez
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$334
MinneapolisGuayaquil
MSP Minneapolis St Paul - GYE Guayaquil Jose Joaquin de Olmedo
MSPGYE
Minneapolis St Paul
Thu 11/26
6:04 pm-8:56 pm
3 stops25h 52m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$338
MinneapolisBogotá
MSP Minneapolis St Paul - BOG Bogotá El Dorado
MSPBOG
Minneapolis St Paul
Thu 11/19
6:10 am-8:10 pm
1 stop13h 00m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$345
MinneapolisQuito
MSP Minneapolis St Paul - UIO Quito Mariscal Sucr
MSPUIO
Minneapolis St Paul
Mon 12/7
3:42 pm-12:36 pm
3 stops43h 54m
Quito Mariscal Sucr
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$346
MinneapolisBogotá
MSP Minneapolis St Paul - BOG Bogotá El Dorado
MSPBOG
Minneapolis St Paul
Sun 1/3
10:45 am-11:55 pm
2 stops36h 10m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$353
MinneapolisGuayaquil
MSP Minneapolis St Paul - GYE Guayaquil Jose Joaquin de Olmedo
MSPGYE
Minneapolis St Paul
Mon 3/1
6:25 am-1:55 am
2 stops18h 30m
Guayaquil Jose Joaquin de Olmedo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$357
MinneapolisBogotá
MSP Minneapolis St Paul - BOG Bogotá El Dorado
MSPBOG
Minneapolis St Paul
Thu 4/1
10:24 am-12:55 pm
1 stop26h 31m
Bogotá El Dorado
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$368
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Minneapolis with our price prediction graph.
MSP-MDE
MSP-GYE
MSP-CTG
MSP-BOG
MSP-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to South America
MSP-0SA
MSP-MDE
MSP-GYE
MSP-CTG
MSP-BOG
What is the cheapest month to book a flight from Minneapolis to South America?
Currently, April is the cheapest month in which you can book a flight from Minneapolis to South America (average of $808). Flying from Minneapolis to South America in December is currently the most expensive (average of $1,289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Minneapolis to South America?
The best time to book flights from Minneapolis to South America is 5 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated October 14, 2026.
Read through reviews of airlines operating flights from Minneapolis to South America, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top countries
Top destinations
Alternative routes for Minneapolis to South America
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to South America by cabin class
Find flights from Minneapolis to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and South America flights
Browse other Minneapolis and South America flight options. Last updated on October 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Minneapolis to South America flights
Consider these flights traveling from Minneapolis to South America.
Top 7 airlines flying from Minneapolis to South America
Discover the top 7 airlines that operate flights from Minneapolis to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$392 | Average$1,233 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$398 | Average$1,234 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$470 | Average$802 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$620 | Average$804 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$640 | Average$1,050 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$646 | Average$1,141 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,106 | Average$1,202 | FlexibilityNo cancel fee | On-time74% |