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South America

$152+ Cheap flights from Irvine, CA to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — BOG
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Irvine to South America

Cheapest flights from Irvine to South America
Explore the most affordable flight options available from Irvine to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This FlightHub deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:43 pmLAX - MDE
1 stop11h 31mSpirit Airlines
Mon 2/23:15 pmMDE - LAX
2 stops29h 47mSpirit Airlines
Deal found 12/17$412
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:55 pmLAX - MDE
1 stop10h 00mAvianca
Mon 2/22:10 pmMDE - LAX
1 stop10h 50mAvianca
Deal found 12/17$437
This FlightHub deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:43 pmLAX - MDE
1 stop11h 31mSpirit Airlines
Sun 1/183:15 pmMDE - LAX
2 stops29h 47mSpirit Airlines
Deal found 12/15$438
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:45 pmLAX - MDE
1 stop24h 20mUnited Airlines
Sat 1/3110:45 amMDE - LAX
1 stop15h 48mUnited Airlines
Deal found 12/16$463
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:43 pmLAX - MDE
1 stop22h 45mMultiple Airlines
Tue 1/1311:50 pmMDE - LAX
2 stops25h 00mMultiple Airlines
Deal found 12/16$475
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:52 amLAX - BOG
1 stop29h 33mCopa Airlines
Fri 12/2610:40 amBOG - LAX
1 stop14h 54mCopa Airlines
Deal found 12/16$475
This LATAM Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:59 pmLAX - BOG
1 stop11h 26mLATAM Airlines
Mon 1/51:35 amBOG - LAX
1 stop12h 26mLATAM Airlines
Deal found 12/15$476
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:43 pmLAX - MDE
1 stop22h 45mMultiple Airlines
Mon 1/1211:50 pmMDE - LAX
2 stops21h 12mMultiple Airlines
Deal found 12/16$478
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:43 pmLAX - MDE
1 stop22h 45mMultiple Airlines
Wed 1/1411:50 pmMDE - LAX
2 stops21h 12mMultiple Airlines
Deal found 12/16$483
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:20 pmLAX - MDE
2 stops37h 54mSpirit Airlines
Sat 1/313:15 pmMDE - LAX
1 stop34h 41mSpirit Airlines
Deal found 12/16$491
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:45 amLAX - GRU
1 stop17h 35mUnited Airlines
Thu 1/19:45 pmGRU - LAX
1 stop17h 05mUnited Airlines
Deal found 12/15$500
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:00 amLAX - GRU
1 stop18h 20mUnited Airlines
Thu 12/1810:15 pmGRU - LAX
1 stop28h 40mUnited Airlines
Deal found 12/15$509

Find flight deals from Irvine to South America

Keep the following information in mind while searching for Irvine to South America flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$336
(Cheapflightsfares)

One-way from

$152
(Super.com)

Popular in

December

Cheapest in

February

Average price

$828
Provider with most accurate pricing for Los Angeles-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Sao Paulo (SAO) flights.
Search Deals
From Irvine to South America
Search Deals
One-way flight from Irvine to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($78 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Irvine to South America that are best for you.

Fly from

Irvine

Fly to

South America

Route

Depart

Return

Price

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Fri 1/30

11:59 pm-2:15 pm

1 stop11h 16m

Medellín Jose Maria Cordova Intl

Fri 2/6

3:15 pm-6:02 pm

2 stops29h 47m

$338

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Tue 1/27

10:25 pm-12:55 pm

1 stop11h 30m

Medellín Jose Maria Cordova Intl

Wed 2/4

2:10 pm-10:00 pm

1 stop10h 50m

$345

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Wed 3/4

11:55 pm-5:05 pm

2 stops14h 10m

Medellín Jose Maria Cordova Intl

Sun 3/8

2:10 pm-10:15 pm

1 stop10h 05m

$351

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Fri 3/6

12:25 pm-6:05 am

3 stops14h 40m

Medellín Jose Maria Cordova Intl

Sat 3/14

2:10 pm-10:15 pm

1 stop10h 05m

$365

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Sun 2/1

11:55 pm-12:55 pm

1 stop10h 00m

Medellín Jose Maria Cordova Intl

Sat 2/7

2:10 pm-9:15 pm

1 stop10h 05m

$376

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Sun 1/18

7:07 pm-2:15 pm

2 stops16h 08m

Medellín Jose Maria Cordova Intl

Fri 1/23

3:15 pm-5:39 pm

2 stops29h 24m

$380

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Wed 1/28

11:55 pm-12:55 pm

1 stop10h 00m

Medellín Jose Maria Cordova Intl

Tue 2/3

2:10 pm-10:00 pm

1 stop10h 50m

$392

Los AngelesMedellín

LAX - MDE

LAXMDE

Los Angeles

Thu 1/15

7:07 pm-2:15 pm

2 stops16h 08m

Medellín Jose Maria Cordova Intl

Mon 1/19

3:15 pm-6:02 pm

2 stops29h 47m

$407

Los AngelesBogotá

LAX - BOG

LAXBOG

Los Angeles

Wed 1/28

10:24 am-10:35 pm

1 stop9h 11m

Bogotá El Dorado

Thu 2/5

8:15 am-7:23 pm

1 stop14h 08m

$423

Los AngelesBogotá

LAX - BOG

LAXBOG

Los Angeles

Mon 2/2

5:50 am-10:35 pm

1 stop13h 45m

Bogotá El Dorado

Fri 2/6

8:15 am-6:15 pm

1 stop13h 00m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/18

Showing 1-10 of 60 results
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Best time to book a flight from Irvine to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to South America

What is the cheapest month to book a flight from Irvine to South America?

Currently, November is the cheapest month in which you can book a flight from Irvine to South America (average of $231). Flying from Irvine to South America in December is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to SA?

Find hourly flight availability from Irvine to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Irvine to South America in the evening. By choosing this option you can save up to 21% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Irvine to South America?

Use this chart to determine the cheapest time to fly round-trip from Irvine to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Irvine to South America flight should consider departing on Tuesday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 18, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from Irvine to South America have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,556 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,893 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Avianca
6.6
Okay
2,490 reviews
Delta
7.9
Good
8,007 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

7.9

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Irvine to South America?

    Airlines like Spirit Airlines, Avianca, and United Airlines fly from Irvine to South America in about 9h 11m. The time it takes to get you to your destination can typically vary by up to 2h 19m. Airlines will cover a distance of 3477 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Irvine to South America one-way?

    The cheapest airlines for a one-way flight from Irvine to South America are Spirit Airlines ($110), Viva ($134), and Avianca ($152).

  • What are the most popular routes from Irvine to South America?

    The most popular route from Irvine to South America is Los Angeles - Lima J Chavez Intl. You may also consider Los Angeles - Medellín Jose Maria Cordova Intl or Los Angeles - Sao Paulo Guarulhos Intl.

  • Can I find deals for flights from Irvine to South America that include hotel bookings?

    Yes. In addition to deals on Irvine to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to South America.

  • Can I find deals for business class flights from Irvine to South America?

    Yes. Cheapflights offers flight deals from Irvine to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to South America?

    Currently, November is the cheapest month in which you can book a flight from Irvine to South America (average of $231). Flying from Irvine to South America in December is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 10 airlines flying from Irvine to South America

Discover the top 10 airlines that operate flights from Irvine to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$152Average$531FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$348Average$779FlexibilityNo cancel feeOn-time69%
AviancaCheapest$348Average$609FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$380Average$675FlexibilityNo cancel feeOn-time70%
JetBlueCheapest$436Average$470FlexibilityNo cancel feeOn-time62%
DeltaCheapest$440Average$841FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$452Average$731FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$452Average$812FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$490Average$700FlexibilityNo cancel feeOn-timeN/A
GOLCheapest$523Average$850FlexibilityNo cancel feeOn-time74%

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