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$216+ Cheap flights from Iowa to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BOG
nov. 29 — dic. 61
sáb. 11/29
sáb. 12/6
1 adult, Economy
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Cheap flight deals from Iowa to South America

Keep the following information in mind while searching for Iowa to South America flight deals. Data was last updated octubre 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$601
(Delta)

One-way from

$216
(Kiwi.com)
Provider with most accurate pricing for Des Moines-Sao Paulo (SAO) flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Sao Paulo (SAO) flights.
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From Iowa to South America
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One-way flight from Iowa to South America
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Find flight deals from Iowa to South America

Cheapest flights from Iowa to South America
Explore the most affordable flight options available from Iowa to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/112:56 pmDSM - LIM
1 stop30h 39mMultiple Airlines
jue. 12/1811:37 pmLIM - DSM
2 stops40h 20mMultiple Airlines
Deal found 10/28$614
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/188:15 amOMA - MDE
1 stop12h 50mUnited Airlines
jue. 11/2710:45 amMDE - OMA
1 stop9h 04mUnited Airlines
Deal found 10/28$633
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/198:15 amOMA - MDE
1 stop12h 50mUnited Airlines
vie. 11/2810:45 amMDE - OMA
1 stop9h 04mUnited Airlines
Deal found 10/28$643
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/88:15 amOMA - BOG
1 stop13h 20mUnited Airlines
vie. 11/288:15 amBOG - OMA
1 stop14h 52mUnited Airlines
Deal found 10/30$652
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/208:15 amOMA - MDE
1 stop12h 50mUnited Airlines
jue. 11/2710:45 amMDE - OMA
1 stop10h 34mUnited Airlines
Deal found 10/28$653
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/208:15 amOMA - MDE
1 stop12h 50mUnited Airlines
mar. 11/2510:45 amMDE - OMA
1 stop12h 22mUnited Airlines
Deal found 10/28$658
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/208:15 amOMA - MDE
1 stop12h 50mUnited Airlines
vie. 11/2810:45 amMDE - OMA
1 stop9h 04mUnited Airlines
Deal found 10/28$663
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/25:00 amOMA - BOG
1 stop15h 35mUnited Airlines
mar. 11/48:15 amBOG - OMA
1 stop14h 52mUnited Airlines
Deal found 10/29$677
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/238:15 amOMA - MDE
1 stop12h 50mUnited Airlines
mar. 11/2510:45 amMDE - OMA
1 stop12h 22mUnited Airlines
Deal found 10/28$683
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/198:15 amOMA - MDE
1 stop12h 50mUnited Airlines
lun. 11/2410:45 amMDE - OMA
1 stop12h 22mUnited Airlines
Deal found 10/28$693
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/218:15 amOMA - MDE
1 stop12h 50mUnited Airlines
mar. 11/2510:45 amMDE - OMA
1 stop12h 22mUnited Airlines
Deal found 10/28$696
This deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/218:15 amOMA - MDE
1 stop12h 50mUnited Airlines
vie. 11/2810:45 amMDE - OMA
1 stop9h 04mUnited Airlines
Deal found 10/28$701

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
Use the filters below to find and compare flights from Iowa to South America that are best for you.

Fly from

Iowa

Fly to

South America

Route

Depart

Return

Price

OmahaBogotá

OMA - BOG

OMABOG

Omaha Eppley Airfield

lun. 3/23

5:35 am-7:30 pm

1 stop13h 55m

Bogotá El Dorado

sáb. 4/4

2:55 pm-10:08 am

1 stop19h 13m

$601

OmahaBogotá

OMA - BOG

OMABOG

Omaha Eppley Airfield

lun. 3/23

9:15 am-10:35 pm

2 stops13h 20m

Bogotá El Dorado

vie. 4/3

12:14 am-5:21 pm

2 stops17h 07m

$606

Des MoinesLima

DSM - LIM

DSMLIM

Des Moines

jue. 12/11

2:56 pm-10:35 pm

1 stop30h 39m

Lima J Chavez Intl

jue. 12/18

11:37 pm-2:57 pm

2 stops40h 20m

$614

OmahaMedellín

OMA - MDE

OMAMDE

Omaha Eppley Airfield

jue. 1/15

3:07 pm-2:06 pm

2 stops21h 59m

Medellín Jose Maria Cordova Intl

dom. 1/18

7:00 am-11:59 pm

1 stop17h 59m

$643

OmahaMedellín

OMA - MDE

OMAMDE

Omaha Eppley Airfield

mié. 11/19

8:15 am-10:05 pm

1 stop12h 50m

Medellín Jose Maria Cordova Intl

vie. 11/28

10:45 am-6:49 pm

1 stop9h 04m

$643

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

jue. 1/15

6:00 am-11:47 pm

2 stops16h 47m

Quito Mariscal Sucr

jue. 1/29

7:04 am-11:29 pm

1 stop17h 25m

$643

Des MoinesQuito

DSM - UIO

DSMUIO

Des Moines

jue. 1/15

8:00 am-12:30 am

2 stops15h 30m

Quito Mariscal Sucr

mié. 1/28

1:35 am-2:22 pm

1 stop13h 47m

$643

OmahaMedellín

OMA - MDE

OMAMDE

Omaha Eppley Airfield

jue. 11/20

8:15 am-10:05 pm

1 stop12h 50m

Medellín Jose Maria Cordova Intl

jue. 11/27

10:45 am-8:19 pm

1 stop10h 34m

$653

OmahaMedellín

OMA - MDE

OMAMDE

Omaha Eppley Airfield

sáb. 11/22

8:15 am-10:05 pm

1 stop12h 50m

Medellín Jose Maria Cordova Intl

jue. 11/27

10:45 am-8:19 pm

1 stop10h 34m

$653

OmahaMedellín

OMA - MDE

OMAMDE

Omaha Eppley Airfield

jue. 11/20

8:15 am-10:05 pm

1 stop12h 50m

Medellín Jose Maria Cordova Intl

mar. 11/25

10:45 am-10:07 pm

1 stop12h 22m

$658

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 48 results
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Best time to book a flight from Iowa to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to South America

What is the cheapest month to book a flight from Iowa to South America?

Currently, February is the cheapest month in which you can book a flight from Iowa to South America (average of $359). Flying from Iowa to South America in November is currently the most expensive (average of $844). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to SA?

Find hourly flight availability from Iowa to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 30, 2025.

It’s typically best to fly out from Iowa to South America in the evening. Doing so could potentially save you 34% on the flight price compared to flying in the morning, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Iowa to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to South America?

    For as low as $606, Delta can have you in South America from Iowa in 13h 20m. The distance from Iowa to South America is about 2862 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Iowa to South America one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $392. However, be on the lookout for offers from Avianca and Delta, as they are both options that can get you from Iowa to South America for a low price.

  • Can I find deals for flights from Iowa to South America that include hotel bookings?

    Yes. In addition to deals on Iowa to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to South America.

  • Can I find deals for business class flights from Iowa to South America?

    Yes. Cheapflights offers flight deals from Iowa to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to South America?

    Currently, February is the cheapest month in which you can book a flight from Iowa to South America (average of $359). Flying from Iowa to South America in November is currently the most expensive (average of $844). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to South America

Discover the top 4 airlines that operate flights from Iowa to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$566Average$772FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$571Average$978FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$585Average$706FlexibilityNo cancel feeOn-time69%
DeltaCheapest$650Average$1,063FlexibilityNo cancel feeOn-timeN/A

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