South America

$209+ Cheap flights from Greenville (GSP) to South America

GSP — BOG
Dec 8 — Dec 151
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Cheap flight deals from Greenville to South America

Cheapest flights from Greenville to South America

Thu 12/314:02 pm -
2 stops30h 58m
Wed 1/273:20 pm -
1 stop23h 21m
Deal found 11/8$543
Mon 11/238:35 pm -
2 stops17h 58m
Mon 11/303:33 pm -
2 stops18h 54m
Deal found 11/5$715
Fri 11/68:35 pm -
2 stops19h 01m
Sat 11/214:34 pm -
2 stops17h 53m
Deal found 11/5$737
Sat 12/267:37 pm -
1 stop18h 50m
Sat 2/63:33 pm -
1 stop8h 26m
Deal found 11/7$748
Mon 12/77:48 pm -
2 stops38h 22m
Sun 12/134:45 am -
2 stops14h 28m
Deal found 11/6$755
Mon 12/288:32 pm -
1 stop15h 28m
Tue 1/121:22 pm -
2 stops44h 10m
Deal found 11/6$757
Fri 12/47:48 pm -
2 stops17h 41m
Tue 12/86:10 am -
2 stops13h 03m
Deal found 11/5$758
Tue 11/1710:52 am -
2 stops9h 49m
Wed 12/26:45 am -
2 stops14h 03m
Deal found 11/4$762
Wed 12/307:41 pm -
2 stops16h 34m
Wed 1/279:00 am -
1 stop11h 43m
Deal found 11/8$763
Tue 12/17:48 pm -
2 stops26h 22m
Sat 12/1210:40 am -
2 stops22h 51m
Deal found 11/5$764
Tue 11/107:55 am -
2 stops14h 25m
Tue 11/248:00 am -
1 stop11h 46m
Deal found 11/5$767
Tue 12/297:41 pm -
1 stop23h 49m
Wed 1/279:00 am -
1 stop14h 52m
Deal found 11/8$769

Find flight deals from Greenville to South America

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$528
(Kiwi.com)

One-way from

$209
(Kiwi.com)
Provider with most accurate pricing for Greenville-Sao Paulo (SAO) flight deals.
Provider most trusted by Cheapflights users for Greenville-Sao Paulo (SAO) flights.
From Greenville to South America
One-way flight from Greenville to South America

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Greenville to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleMedellín

GSP Greenville - MDE Medellín Jose Maria Cordova Intl

GSPMDE

Greenville

Sun 12/13

3:49 pm-12:00 pm

1 stop20h 11m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$293

GreenvilleMedellín

GSP Greenville - MDE Medellín Jose Maria Cordova Intl

GSPMDE

Greenville

Mon 12/28

8:32 pm-12:07 am

2 stops27h 35m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$339

GreenvilleLima

GSP Greenville - LIM Lima J Chavez Intl

GSPLIM

Greenville

Sun 12/6

4:02 pm-4:55 am

2 stops36h 53m

Lima J Chavez Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$385

GreenvilleCali

GSP Greenville - CLO Cali Alfonso B. Aragon Intl

GSPCLO

Greenville

Fri 12/25

8:32 pm-7:05 am

2 stops34h 33m

Cali Alfonso B. Aragon Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$387

GreenvilleBogotá

GSP Greenville - BOG Bogotá El Dorado

GSPBOG

Greenville

Sun 12/13

4:02 pm-5:30 pm

2 stops25h 28m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$387

GreenvilleBuenos Aires

GSP Greenville - EZE Buenos Aires Ministro Pistarini

GSPEZE

Greenville

Mon 1/18

8:32 pm-3:15 am

3 stops52h 43m

Buenos Aires Ministro Pistarini

Wed 12/31

12:00 am-10:00 pm

Nonstop0h 00m

$405

GreenvilleBogotá

GSP Greenville - BOG Bogotá El Dorado

GSPBOG

Greenville

Wed 11/25

5:05 pm-6:45 pm

1 stop25h 40m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$422

GreenvilleCali

GSP Greenville - CLO Cali Alfonso B. Aragon Intl

GSPCLO

Greenville

Tue 1/26

7:00 am-2:32 pm

1 stop7h 32m

Cali Alfonso B. Aragon Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$430
Quickest round-trip

GreenvilleMedellín

GSP Greenville - MDE Medellín Jose Maria Cordova Intl

GSPMDE

Greenville

Wed 2/3

7:00 am-2:01 pm

1 stop7h 01m

Medellín Jose Maria Cordova Intl

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$440

GreenvilleBogotá

GSP Greenville - BOG Bogotá El Dorado

GSPBOG

Greenville

Tue 11/17

11:28 am-5:00 pm

3 stops29h 32m

Bogotá El Dorado

Wed 12/31

12:00 am-12:00 am

Nonstop0h 00m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Greenville to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Greenville to South America

What is the cheapest month to book a flight from Greenville to South America?

Currently, February is the cheapest month in which you can book a flight from Greenville to South America (average of $640). Flying from Greenville to South America in December is currently the most expensive (average of $1,176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing South America

Read through reviews of airlines operating flights from Greenville to South America, such as Delta,LATAM Airlines, andGOL. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.8

Comfort

7.8

Crew

8.5

Reviews

1 / 20
6.0
Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

  • What airport do you fly from for flights from Greenville to South America?

    For a flight from Greenville to South America, you will be flying from Greenville. Greenville (GSP) is just 10.4 mi from the center of the city.

  • How long is the flight from Greenville to South America?

    American Airlines, Delta, and United Airlines can get you from Greenville to South America in just under 7h 46m. Your travel time can differ by up to 14h 23m. The distance from Greenville to South America is about 1740 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Greenville to South America?

  • Can I find deals for flights from Greenville to South America that include hotel bookings?

    Yes. In addition to deals on Greenville to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to South America.

  • Can I find deals for business class flights from Greenville to South America?

    Yes. Cheapflights offers flight deals from Greenville to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to South America?

    Currently, February is the cheapest month in which you can book a flight from Greenville to South America (average of $640). Flying from Greenville to South America in December is currently the most expensive (average of $1,176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Greenville to South America

Top 3 airlines flying from Greenville to South America

AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$523Average$843FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$535Average$806FlexibilityNo cancel feeOn-time81%
DeltaCheapest$637Average$930FlexibilityNo cancel feeOn-timeN/A

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