$170+ Cheap flights from Greenville (GSP) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/22. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
Mar 29 — Apr 51
1 adult, Economy
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Find cheap flights from Greenville to South America with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to South America
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Cheapest flights from Greenville to South AmericaExplore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- MDE
1 stop7h 38m
Multiple Airlines
Thu 4/161:11 am
MDE
- GSP
1 stop14h 42m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:46 pm
GSP
- MDE
1 stop27h 35m
Multiple Airlines
Thu 4/302:06 pm
MDE
- GSP
1 stop25h 47m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- MDE
1 stop7h 38m
Multiple Airlines
Thu 4/162:06 pm
MDE
- GSP
1 stop25h 47m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:36 pm
GSP
- MDE
1 stop8h 45m
Multiple Airlines
Sat 4/41:17 am
MDE
- GSP
1 stop13h 30m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:18 pm
GSP
- BOG
1 stop16h 37m
Multiple Airlines
Wed 3/259:35 pm
BOG
- GSP
2 stops22h 21m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$390
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:12 pm
GSP
- CTG
2 stops22h 54m
Multiple Airlines
Sun 4/191:11 pm
CTG
- GSP
1 stop26h 42m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- CTG
1 stop19h 23m
Multiple Airlines
Fri 4/176:55 am
CTG
- GSP
2 stops11h 43m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:43 pm
GSP
- BOG
1 stop20h 25m
Multiple Airlines
Wed 4/292:07 pm
BOG
- GSP
2 stops22h 05m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$420
This Avianca deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:41 pm
GSP
- BOG
1 stop12h 49m
Multiple Airlines
Tue 9/89:05 am
BOG
- GSP
2 stops11h 41m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:43 pm
GSP
- BOG
1 stop20h 25m
Multiple Airlines
Sun 5/2410:35 am
BOG
- GSP
1 stop19h 58m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$431
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- CTG
1 stop19h 23m
Multiple Airlines
Sun 4/193:00 am
CTG
- GSP
2 stops15h 38m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$433
This Avianca deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:32 pm
GSP
- MDE
2 stops22h 58m
Avianca
Sun 3/157:00 pm
MDE
- GSP
2 stops38h 01m
Avianca
Deal found 2/27![Avianca logo]()
$446
Best flights from Greenville to South AmericaDiscover carefully curated flight deals from Greenville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
Discover carefully curated flight deals from Greenville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- MDE
1 stop7h 38m
Multiple Airlines
Thu 4/161:11 am
MDE
- GSP
1 stop14h 42m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
GSP
- BOG
2 stops17h 00m
United Airlines
Mon 6/2912:14 am
BOG
- GSP
2 stops20h 03m
United Airlines
Deal found 2/26![United Airlines logo]()
$506
This Avianca deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:32 pm
GSP
- MDE
2 stops17h 28m
Avianca
Sun 3/1510:45 pm
MDE
- GSP
2 stops34h 16m
Avianca
Deal found 2/24![Avianca logo]()
$529
This FlightHub deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:45 am
GSP
- BOG
1 stop13h 30m
LATAM Airlines
Sat 5/232:55 pm
BOG
- GSP
1 stop7h 53m
LATAM Airlines
Deal found 2/23![LATAM Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:45 am
GSP
- BOG
1 stop8h 02m
Delta
Fri 9/255:00 am
BOG
- GSP
2 stops17h 38m
Delta
Deal found 2/25![Delta logo]()
$535
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:00 am
GSP
- CTG
1 stop7h 09m
American Airlines
Fri 4/173:10 pm
CTG
- GSP
1 stop7h 49m
American Airlines
Deal found 2/24![American Airlines logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- MDE
2 stops28h 46m
Multiple Airlines
Thu 4/162:06 pm
MDE
- GSP
1 stop25h 47m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:12 pm
GSP
- CTG
2 stops22h 54m
Multiple Airlines
Sun 4/191:11 pm
CTG
- GSP
1 stop26h 42m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:00 am
GSP
- MDE
1 stop15h 10m
United Airlines
Tue 5/129:45 am
MDE
- GSP
1 stop11h 29m
United Airlines
Deal found 2/26![United Airlines logo]()
$520
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 pm
GSP
- BOG
2 stops20h 00m
Delta
Sat 5/239:00 am
BOG
- GSP
1 stop10h 13m
Delta
Deal found 2/23![Delta logo]()
$535
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/125:20 am
GSP
- CTG
2 stops9h 44m
American Airlines
Sun 4/191:25 pm
CTG
- GSP
2 stops19h 54m
American Airlines
Deal found 2/26![American Airlines logo]()
$550
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:00 am
GSP
- MDE
1 stop15h 10m
United Airlines
Tue 5/199:45 am
MDE
- GSP
1 stop11h 29m
United Airlines
Deal found 2/26![United Airlines logo]()
$520
This Delta deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:05 pm
GSP
- BOG
2 stops20h 00m
Delta
Sun 5/2411:00 am
BOG
- GSP
2 stops22h 17m
Delta
Deal found 2/23![Delta logo]()
$540
This KAYAK deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:30 am
GSP
- CTG
1 stop5h 45m
LATAM Airlines
Mon 4/139:20 am
CTG
- GSP
2 stops13h 36m
LATAM Airlines
Deal found 2/24![LATAM Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 am
GSP
- MDE
2 stops15h 55m
American Airlines
Fri 4/176:00 am
MDE
- GSP
2 stops16h 57m
American Airlines
Deal found 2/24![American Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:33 pm
GSP
- BOG
2 stops17h 21m
United Airlines
Mon 4/2012:14 am
BOG
- GSP
2 stops15h 38m
United Airlines
Deal found 2/27![United Airlines logo]()
$532
This Avianca deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:00 am
GSP
- CTG
2 stops39h 45m
Avianca
Wed 8/129:55 pm
CTG
- GSP
2 stops46h 16m
Avianca
Deal found 2/25![Avianca logo]()
$660
This BusinessClass deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:45 am
GSP
- CTG
2 stops16h 50m
LATAM Airlines
Sat 7/252:30 pm
CTG
- GSP
1 stop17h 57m
LATAM Airlines
Deal found 2/24![LATAM Airlines logo]()
$611
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:00 am
GSP
- MDE
2 stops14h 15m
American Airlines
Mon 4/206:00 am
MDE
- GSP
2 stops15h 19m
American Airlines
Deal found 2/27![American Airlines logo]()
$565
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- LIM
1 stop28h 52m
Multiple Airlines
Mon 4/204:00 am
LIM
- GSP
2 stops15h 07m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$570
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:36 am
GSP
- BOG
2 stops13h 44m
United Airlines
Sun 5/248:30 am
BOG
- GSP
1 stop12h 29m
United Airlines
Deal found 2/23![United Airlines logo]()
$535
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:30 am
GSP
- CTG
1 stop5h 45m
Delta
Mon 4/134:25 am
CTG
- GSP
2 stops18h 31m
Delta
Deal found 2/25![Delta logo]()
$620
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:05 pm
GSP
- CTG
2 stops19h 04m
American Airlines
Mon 4/203:10 pm
CTG
- GSP
2 stops19h 19m
American Airlines
Deal found 2/27![American Airlines logo]()
$570
This Gurufare deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:06 am
GSP
- UIO
1 stop8h 53m
LATAM Airlines
Wed 5/612:59 am
UIO
- GSP
1 stop8h 46m
LATAM Airlines
Deal found 2/25![LATAM Airlines logo]()
$647
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:30 am
GSP
- BOG
2 stops13h 50m
United Airlines
Tue 4/288:30 am
BOG
- GSP
1 stop12h 29m
United Airlines
Deal found 2/27![United Airlines logo]()
$537
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:12 pm
GSP
- LIM
2 stops35h 38m
Multiple Airlines
Sun 4/1910:35 pm
LIM
- GSP
1 stop17h 18m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$646
This Delta deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:42 am
GSP
- UIO
1 stop14h 17m
Delta
Wed 5/612:59 am
UIO
- GSP
1 stop8h 46m
Delta
Deal found 2/26![Delta logo]()
$647
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/162:45 pm
GSP
- BOG
2 stops15h 09m
United Airlines
Sun 5/248:30 am
BOG
- GSP
2 stops24h 25m
United Airlines
Deal found 2/23![United Airlines logo]()
$540
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:17 pm
GSP
- CTG
2 stops17h 10m
American Airlines
Fri 3/271:28 pm
CTG
- GSP
2 stops18h 10m
American Airlines
Deal found 2/26![American Airlines logo]()
$626
This Gotogate deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:33 am
GSP
- SDU
3 stops29h 12m
Air Canada
Mon 4/201:50 pm
SDU
- GSP
3 stops28h 02m
Air Canada
Deal found 2/27![Air Canada logo]()
$1,886
Last-minute flights from Greenville to South AmericaDiscover last-minute flight deals from Greenville to South America. Data last updated February 27, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to South America. Data last updated February 27, 2026 and is based on user searches.
This Justfly.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/105:32 pm
GSP
- PEI
2 stops24h 03m
Avianca
Mon 4/135:15 am
PEI
- GSP
2 stops27h 31m
Avianca
Deal found 2/26![Avianca logo]()
$489
This Avianca deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:32 pm
GSP
- MDE
2 stops22h 58m
Avianca
Sun 3/157:00 pm
MDE
- GSP
2 stops38h 01m
Avianca
Deal found 2/27![Avianca logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:18 pm
GSP
- BOG
1 stop16h 37m
Multiple Airlines
Wed 3/252:10 pm
BOG
- GSP
1 stop29h 46m
Multiple Airlines
Deal found 2/23![Multiple Airlines logo]()
$390
This Booking.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/235:32 pm
GSP
- MDE
2 stops16h 33m
Avianca
Tue 3/319:05 pm
MDE
- GSP
2 stops35h 41m
Avianca
Deal found 2/26![Avianca logo]()
$501
This Kiwi.com deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/269:46 pm
GSP
- MDE
1 stop27h 35m
Multiple Airlines
Thu 4/302:06 pm
MDE
- GSP
1 stop25h 47m
Multiple Airlines
Deal found 2/24![Multiple Airlines logo]()
$353
This Avianca deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:33 am
GSP
- BOG
1 stop10h 32m
Multiple Airlines
Tue 4/214:25 am
BOG
- GSP
2 stops16h 34m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:36 am
GSP
- BOG
2 stops19h 18m
United Airlines
Mon 4/2012:14 am
BOG
- GSP
2 stops15h 38m
United Airlines
Deal found 2/25![United Airlines logo]()
$529
This American Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:40 am
GSP
- MDE
1 stop7h 30m
American Airlines
Tue 5/121:53 pm
MDE
- GSP
1 stop9h 06m
American Airlines
Deal found 2/27![American Airlines logo]()
$540
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:30 am
GSP
- MDE
2 stops15h 40m
United Airlines
Tue 5/129:45 am
MDE
- GSP
2 stops23h 13m
United Airlines
Deal found 2/27![United Airlines logo]()
$545
This United Airlines deal was found by Cheapflights users on 2/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:41 pm
GSP
- BOG
1 stop13h 13m
United Airlines
Sat 5/28:30 am
BOG
- GSP
1 stop12h 44m
United Airlines
Deal found 2/23![United Airlines logo]()
$547
This United Airlines deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:30 am
GSP
- BOG
2 stops23h 24m
United Airlines
Fri 4/248:30 am
BOG
- GSP
2 stops24h 25m
United Airlines
Deal found 2/24![United Airlines logo]()
$552
This Delta deal was found by Cheapflights users on 2/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3110:13 am
GSP
- BOG
1 stop10h 02m
Delta
Tue 4/219:00 am
BOG
- GSP
1 stop13h 56m
Delta
Deal found 2/24![Delta logo]()
$558
One-way flights from Greenville to South AmericaSearch for one-way flight options from Greenville to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
Search for one-way flight options from Greenville to South America. Find affordable one-way fares based on user searches. Data last updated February 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/229:46 pm
GSP
- PEI
2 stops33h 49m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/199:46 pm
GSP
- PEI
2 stops43h 19m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1910:38 am
GSP
- BOG
1 stop10h 57m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/204:07 pm
GSP
- PEI
3 stops49h 00m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:18 pm
GSP
- PEI
3 stops44h 47m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/155:43 pm
GSP
- CTG
1 stop19h 22m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$194
This Avianca deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:36 pm
GSP
- PEI
2 stops16h 34m
Avianca
Deal found 2/27![Avianca logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/154:46 pm
GSP
- CTG
1 stop20h 20m
Multiple Airlines
Deal found 2/25![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- UIO
2 stops45h 57m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/154:46 pm
GSP
- MDE
1 stop8h 35m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/154:46 pm
GSP
- PEI
2 stops38h 49m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/122:12 pm
GSP
- MDE
3 stops43h 18m
Multiple Airlines
Deal found 2/26![Multiple Airlines logo]()
$224
Find flight deals from Greenville to South America
Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated February 27, 2026.
Round-trip from | $311 (Kiwi.com) |
|---|---|
One-way from | $170 (Kiwi.com) |
Popular in | September |
Cheapest in | April |
Average price | $786 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
Use the filters below to find and compare flights from Greenville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Fri 4/10
5:43 pm-12:21 am
1 stop7h 38m
Medellín Jose Maria Cordova Intl
Thu 4/16
1:11 am-4:53 pm
1 stop14h 42m
$311
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Fri 4/10
5:43 pm-9:29 pm
2 stops28h 46m
Medellín Jose Maria Cordova Intl
Thu 4/16
2:06 pm-4:53 pm
1 stop25h 47m
$407
GreenvilleCartagena
GSP - CTG
GSPCTG
Greenville
Sun 4/12
2:12 pm-12:06 pm
2 stops22h 54m
Cartagena Rafael Nunez
Sun 4/19
1:11 pm-4:53 pm
1 stop26h 42m
$408
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Wed 5/27
6:00 am-10:00 pm
2 stops17h 00m
Bogotá El Dorado
Mon 6/29
12:14 am-9:17 pm
2 stops20h 03m
$506
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Tue 5/5
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Tue 5/12
9:45 am-10:14 pm
1 stop11h 29m
$520
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Tue 5/12
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Tue 5/19
9:45 am-10:14 pm
1 stop11h 29m
$520
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Wed 3/11
5:32 pm-10:00 am
2 stops17h 28m
Medellín Jose Maria Cordova Intl
Sun 3/15
10:45 pm-10:01 am
2 stops34h 16m
$529
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Tue 3/31
12:33 pm-4:54 am
2 stops17h 21m
Bogotá El Dorado
Mon 4/20
12:14 am-4:52 pm
2 stops15h 38m
$532
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Sat 5/9
6:45 am-7:15 pm
1 stop13h 30m
Bogotá El Dorado
Sat 5/23
2:55 pm-11:48 pm
1 stop7h 53m
$535
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Fri 8/7
6:45 am-1:47 pm
1 stop8h 02m
Bogotá El Dorado
Fri 9/25
5:00 am-11:38 pm
2 stops17h 38m
$535
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Greenville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
GSP-BOG
GSP-PEI
GSP-MDE
GSP-CTG
GSP-UIO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to South America
GSP-0SA
GSP-BOG
GSP-PEI
GSP-MDE
GSP-CTG
What is the cheapest month to book a flight from Greenville to South America?
Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in June is currently the most expensive (average of $487). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 27, 2026.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta, LATAM Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Greenville to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to South America by cabin class
Find flights from Greenville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and South America flights
Browse other Greenville and South America flight options. Last updated on February 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Greenville to South America flights
Consider these flights traveling from Greenville to South America.
Top 3 airlines flying from Greenville to South America
Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$494 | Average$808 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$502 | Average$863 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$794 | FlexibilityNo cancel fee | On-timeN/A |