$145+ Cheap flights from Greenville (GSP) to South America
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — BOG
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to South America with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Greenville to South AmericaExplore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from Greenville to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:33 am
GSP
- MDE
1 stop28h 27m
Multiple Airlines
Wed 5/133:25 am
MDE
- GSP
2 stops36h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:12 pm
GSP
- CTG
2 stops22h 54m
Multiple Airlines
Thu 4/301:11 pm
CTG
- GSP
1 stop26h 42m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:28 pm
GSP
- BOG
2 stops19h 42m
Multiple Airlines
Thu 5/142:08 pm
BOG
- GSP
1 stop25h 45m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2610:23 am
GSP
- MDE
1 stop27h 37m
Multiple Airlines
Fri 5/811:10 pm
MDE
- GSP
2 stops32h 33m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
GSP
- MDE
1 stop17h 32m
Multiple Airlines
Fri 5/1511:10 pm
MDE
- GSP
2 stops32h 33m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:18 pm
GSP
- MDE
1 stop17h 42m
Multiple Airlines
Fri 5/86:20 pm
MDE
- GSP
2 stops37h 23m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:17 pm
GSP
- MDE
1 stop22h 26m
Multiple Airlines
Sun 6/72:06 pm
MDE
- GSP
1 stop21h 26m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$495
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:06 pm
GSP
- MDE
1 stop10h 19m
Multiple Airlines
Sun 8/161:00 pm
MDE
- GSP
1 stop27h 39m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$497
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- MDE
1 stop7h 38m
Multiple Airlines
Thu 4/1610:35 am
MDE
- GSP
2 stops32h 03m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- BOG
1 stop20h 28m
Multiple Airlines
Sun 4/196:25 am
BOG
- GSP
2 stops33h 28m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- BOG
1 stop20h 28m
Multiple Airlines
Mon 4/209:00 am
BOG
- GSP
1 stop10h 07m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:35 am
GSP
- MDE
2 stops27h 25m
Multiple Airlines
Thu 5/281:55 pm
MDE
- GSP
1 stop24h 48m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$517
Best flights from Greenville to South AmericaDiscover carefully curated flight deals from Greenville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from Greenville to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:28 pm
GSP
- BOG
2 stops19h 42m
Multiple Airlines
Thu 5/142:08 pm
BOG
- GSP
1 stop25h 45m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$438
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:45 am
GSP
- BOG
1 stop13h 30m
Delta
Sat 8/292:55 pm
BOG
- GSP
1 stop7h 43m
Delta
Deal found 4/4![Delta logo]()
$555
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:00 am
GSP
- MDE
1 stop15h 10m
United Airlines
Tue 9/299:45 am
MDE
- GSP
1 stop11h 01m
United Airlines
Deal found 4/4![United Airlines logo]()
$574
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:08 pm
GSP
- CTG
2 stops21h 05m
American Airlines
Sat 5/303:15 pm
CTG
- GSP
2 stops18h 33m
American Airlines
Deal found 4/8![American Airlines logo]()
$580
This BusinessClass deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:45 am
GSP
- CTG
2 stops13h 45m
LATAM Airlines
Sun 8/239:25 am
CTG
- GSP
2 stops24h 33m
LATAM Airlines
Deal found 4/7![LATAM Airlines logo]()
$619
This Avianca deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:30 am
GSP
- PEI
2 stops38h 35m
Avianca
Mon 8/175:00 pm
PEI
- GSP
2 stops51h 17m
Avianca
Deal found 4/8![Avianca logo]()
$729
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:06 pm
GSP
- MDE
1 stop10h 19m
Multiple Airlines
Sun 8/1610:45 pm
MDE
- GSP
2 stops17h 54m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$507
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:45 am
GSP
- BOG
1 stop11h 30m
Delta
Sun 6/75:00 am
BOG
- GSP
2 stops17h 59m
Delta
Deal found 4/5![Delta logo]()
$555
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:00 pm
GSP
- MDE
1 stop17h 51m
American Airlines
Mon 8/176:00 am
MDE
- GSP
1 stop11h 14m
American Airlines
Deal found 4/5![American Airlines logo]()
$583
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:30 am
GSP
- MDE
2 stops15h 40m
United Airlines
Sat 9/269:45 am
MDE
- GSP
1 stop11h 01m
United Airlines
Deal found 4/7![United Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/248:52 am
GSP
- BOG
2 stops12h 18m
Delta
Tue 8/42:55 pm
BOG
- GSP
1 stop17h 18m
Delta
Deal found 4/6![Delta logo]()
$562
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:44 pm
GSP
- MDE
1 stop19h 06m
American Airlines
Sat 8/2912:25 am
MDE
- GSP
1 stop16h 49m
American Airlines
Deal found 4/7![American Airlines logo]()
$584
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:50 pm
GSP
- BOG
2 stops19h 15m
Delta
Tue 5/125:15 pm
BOG
- GSP
2 stops16h 20m
Delta
Deal found 4/6![Delta logo]()
$578
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:18 am
GSP
- PEI
2 stops34h 02m
United Airlines
Sun 6/75:15 am
PEI
- GSP
2 stops33h 44m
United Airlines
Deal found 4/5![United Airlines logo]()
$641
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:13 pm
GSP
- CTG
2 stops18h 51m
American Airlines
Fri 5/153:10 pm
CTG
- GSP
1 stop7h 49m
American Airlines
Deal found 4/5![American Airlines logo]()
$612
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/206:30 am
GSP
- MDE
2 stops39h 40m
United Airlines
Thu 9/249:45 am
MDE
- GSP
1 stop11h 01m
United Airlines
Deal found 4/7![United Airlines logo]()
$647
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:00 am
GSP
- MDE
1 stop18h 58m
American Airlines
Tue 8/1112:25 am
MDE
- GSP
1 stop16h 49m
American Airlines
Deal found 4/6![American Airlines logo]()
$612
This LATAM Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/33:03 pm
GSP
- LIM
1 stop14h 57m
LATAM Airlines
Sun 5/1012:05 pm
LIM
- GSP
1 stop10h 38m
LATAM Airlines
Deal found 4/4![LATAM Airlines logo]()
$832
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:32 pm
GSP
- CTG
2 stops19h 03m
American Airlines
Fri 5/293:15 pm
CTG
- GSP
2 stops18h 33m
American Airlines
Deal found 4/7![American Airlines logo]()
$615
This Ovago deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:59 pm
GSP
- LIM
1 stop10h 01m
LATAM Airlines
Wed 4/2912:05 pm
LIM
- GSP
1 stop10h 51m
LATAM Airlines
Deal found 4/6![LATAM Airlines logo]()
$835
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:30 am
GSP
- CTG
1 stop8h 40m
American Airlines
Sun 8/233:10 pm
CTG
- GSP
1 stop26h 04m
American Airlines
Deal found 4/7![American Airlines logo]()
$635
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:45 am
GSP
- LIM
2 stops15h 50m
Delta
Sat 5/238:55 am
LIM
- GSP
2 stops13h 53m
Delta
Deal found 4/7![Delta logo]()
$839
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:00 am
GSP
- CTG
1 stop7h 09m
American Airlines
Thu 4/301:25 pm
CTG
- GSP
1 stop9h 34m
American Airlines
Deal found 4/9![American Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/227:49 pm
GSP
- PEI
2 stops25h 31m
United Airlines
Fri 5/295:15 am
PEI
- GSP
2 stops39h 44m
United Airlines
Deal found 4/7![United Airlines logo]()
$1,039
This BusinessClass deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:45 am
GSP
- GIG
2 stops21h 25m
LATAM Airlines
Tue 9/19:00 pm
GIG
- GSP
1 stop13h 27m
LATAM Airlines
Deal found 4/4![LATAM Airlines logo]()
$1,244
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:18 am
GSP
- PEI
2 stops34h 02m
United Airlines
Sun 6/145:15 am
PEI
- GSP
2 stops28h 22m
United Airlines
Deal found 4/8![United Airlines logo]()
$1,042
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/258:15 pm
GSP
- LIM
1 stop8h 55m
American Airlines
Fri 5/296:30 am
LIM
- GSP
1 stop16h 29m
American Airlines
Deal found 4/6![American Airlines logo]()
$807
This BusinessClass deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:42 pm
GSP
- GIG
2 stops18h 03m
LATAM Airlines
Sun 9/275:20 pm
GIG
- GSP
2 stops18h 38m
LATAM Airlines
Deal found 4/5![LATAM Airlines logo]()
$1,250
This KAYAK deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:05 pm
GSP
- SDU
2 stops19h 05m
LATAM Airlines
Tue 9/18:15 pm
SDU
- GSP
2 stops15h 43m
LATAM Airlines
Deal found 4/5![LATAM Airlines logo]()
$1,273
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1311:38 am
GSP
- EZE
2 stops20h 42m
Delta
Fri 7/248:10 pm
EZE
- GSP
1 stop18h 51m
Delta
Deal found 4/7![Delta logo]()
$1,356
Last-minute flights from Greenville to South AmericaDiscover last-minute flight deals from Greenville to South America. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to South America. Data last updated April 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- BOG
1 stop20h 28m
Multiple Airlines
Sun 4/196:25 am
BOG
- GSP
2 stops33h 28m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$510
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:43 pm
GSP
- BOG
1 stop20h 28m
Multiple Airlines
Mon 4/209:00 am
BOG
- GSP
1 stop10h 07m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:43 pm
GSP
- MDE
1 stop7h 38m
Multiple Airlines
Thu 4/1610:35 am
MDE
- GSP
2 stops32h 03m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/262:12 pm
GSP
- CTG
2 stops22h 54m
Multiple Airlines
Thu 4/301:11 pm
CTG
- GSP
1 stop26h 42m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/2610:23 am
GSP
- MDE
1 stop27h 37m
Multiple Airlines
Fri 5/811:10 pm
MDE
- GSP
2 stops32h 33m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:18 pm
GSP
- MDE
1 stop17h 42m
Multiple Airlines
Fri 5/86:20 pm
MDE
- GSP
2 stops37h 23m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:33 am
GSP
- MDE
1 stop28h 27m
Multiple Airlines
Wed 5/133:25 am
MDE
- GSP
2 stops36h 28m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
GSP
- MDE
1 stop17h 32m
Multiple Airlines
Fri 5/1511:10 pm
MDE
- GSP
2 stops32h 33m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 pm
GSP
- MDE
1 stop17h 32m
Multiple Airlines
Tue 5/121:55 pm
MDE
- GSP
2 stops52h 54m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$529
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:28 pm
GSP
- BOG
2 stops19h 42m
Multiple Airlines
Thu 5/142:08 pm
BOG
- GSP
1 stop25h 45m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:35 am
GSP
- MDE
2 stops27h 25m
Multiple Airlines
Thu 5/281:55 pm
MDE
- GSP
1 stop24h 48m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$517
This LATAM Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:45 am
GSP
- BOG
2 stops10h 05m
Multiple Airlines
Tue 6/3011:00 am
BOG
- GSP
2 stops11h 59m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$539
One-way flights from Greenville to South AmericaSearch for one-way flight options from Greenville to South America. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from Greenville to South America. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:43 pm
GSP
- BOG
1 stop20h 29m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:17 pm
GSP
- BOG
1 stop22h 46m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:18 pm
GSP
- BOG
2 stops22h 37m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:43 pm
GSP
- MDE
1 stop20h 25m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:18 pm
GSP
- BOG
1 stop23h 27m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:05 pm
GSP
- BOG
1 stop20h 58m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:29 am
GSP
- GIG
2 stops22h 06m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:29 am
GSP
- SDU
2 stops25h 21m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:12 pm
GSP
- MDE
1 stop12h 38m
American Airlines
Deal found 4/5![American Airlines logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:15 pm
GSP
- LIM
1 stop8h 55m
American Airlines
Deal found 4/8![American Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/68:45 am
GSP
- LIM
1 stop14h 10m
Delta
Deal found 4/8![Delta logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:40 pm
GSP
- LIM
3 stops33h 10m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$624
Find flight deals from Greenville to South America
Keep the following information in mind while searching for Greenville to South America flight deals. Data was last updated April 9, 2026.
Round-trip from | $416 (Kiwi.com) |
|---|---|
One-way from | $145 (Trip.com) |
Popular in | October |
Cheapest in | August |
Average price | $883 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from Greenville to South America that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Mon 5/11
8:28 pm-3:10 pm
2 stops19h 42m
Bogotá El Dorado
Thu 5/14
2:08 pm-4:53 pm
1 stop25h 45m
$438
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Fri 7/31
12:06 pm-9:25 pm
1 stop10h 19m
Medellín Jose Maria Cordova Intl
Sun 8/16
10:45 pm-5:39 pm
2 stops17h 54m
$507
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Fri 8/21
6:45 am-7:15 pm
1 stop13h 30m
Bogotá El Dorado
Sat 8/29
2:55 pm-11:38 pm
1 stop7h 43m
$555
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Fri 5/29
8:45 am-7:15 pm
1 stop11h 30m
Bogotá El Dorado
Sun 6/7
5:00 am-11:59 pm
2 stops17h 59m
$555
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Fri 7/24
8:52 am-8:10 pm
2 stops12h 18m
Bogotá El Dorado
Tue 8/4
2:55 pm-9:13 am
1 stop17h 18m
$562
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Fri 9/25
7:00 am-9:10 pm
1 stop15h 10m
Medellín Jose Maria Cordova Intl
Tue 9/29
9:45 am-9:46 pm
1 stop11h 01m
$574
GreenvilleBogotá
GSP - BOG
GSPBOG
Greenville
Tue 5/5
5:50 pm-12:05 pm
2 stops19h 15m
Bogotá El Dorado
Tue 5/12
5:15 pm-10:35 am
2 stops16h 20m
$578
GreenvilleCartagena
GSP - CTG
GSPCTG
Greenville
Sat 5/23
6:08 pm-2:13 pm
2 stops21h 05m
Cartagena Rafael Nunez
Sat 5/30
3:15 pm-10:48 am
2 stops18h 33m
$580
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Thu 7/30
8:00 pm-12:51 pm
1 stop17h 51m
Medellín Jose Maria Cordova Intl
Mon 8/17
6:00 am-6:14 pm
1 stop11h 14m
$583
GreenvilleMedellín
GSP - MDE
GSPMDE
Greenville
Wed 8/26
6:44 pm-12:50 pm
1 stop19h 06m
Medellín Jose Maria Cordova Intl
Sat 8/29
12:25 am-6:14 pm
1 stop16h 49m
$584
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Greenville to South America
Have a flexible travel schedule? Discover the best time to fly to South America from Greenville with our price prediction graph.
GSP-MDE
GSP-CTG
GSP-BOG
GSP-PEI
GSP-LIM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to South America
GSP-0SA
GSP-MDE
GSP-CTG
GSP-BOG
GSP-PEI
What is the cheapest month to book a flight from Greenville to South America?
Currently, October is the cheapest month in which you can book a flight from Greenville to South America (average of $96). Flying from Greenville to South America in July is currently the most expensive (average of $354). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing South America
Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated April 9, 2026.
Read through reviews of airlines operating flights from Greenville to South America, such as Delta,LATAM Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Overall
7.9
Entertainment
7.8
Boarding
8.1
Comfort
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Greenville to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Greenville to South America
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Complete your trip
Complete your trip to South America by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Greenville to South America by cabin class
Find flights from Greenville to South America, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Greenville and South America flights
Browse other Greenville and South America flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Fly to South America countries
Consider these flights traveling to countries located in South America.
Greenville to South America flights
Consider these flights traveling from Greenville to South America.
Top 3 airlines flying from Greenville to South America
Discover the top 3 airlines that operate flights from Greenville to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$502 | Average$843 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$535 | Average$913 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$536 | Average$809 | FlexibilityNo cancel fee | On-timeN/A |