$160+ Cheap flights from Des Moines to San Francisco (DSM - SFO)

Frontier and Delta can get you from Des Moines to San Francisco in just under 6h 08m. Your travel time can differ by up to 8h 24m. Airlines will cover a distance of 1545 mi. This flight may include one or multiple stops.

Our cheapest airline available from Des Moines to San Francisco is Frontier. Our recent data shows that you can find tickets from as low as $110 on this airline. Additional options worth looking into are Delta and American Airlines, starting at $263 and $336 round-trip. Frontier is currently priced 74% below the average price you’ll pay for this route.

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $89. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Des Moines to San Francisco for a low price.

Yes. In addition to deals on Des Moines to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Francisco.

Yes. Cheapflights offers flight deals from Des Moines to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Currently, December is the cheapest month in which you can book a flight from Des Moines to San Francisco (average of $169). Flying from Des Moines to San Francisco in May is currently the most expensive (average of $304). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.