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$338+ Cheap flights from La Crosse to San Diego (LSE - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SAN
Jul 14 — Jul 211
Tue 7/14
Tue 7/21
1 adult, Economy
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Cheap flight deals from La Crosse to San Diego

Cheapest flights from La Crosse to San Diego
Explore the most affordable flight options available from La Crosse to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.

This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:21 pm
LSE
-
SAN
1 stop8h 58m
American Airlines
Sat 9/51:14 pm
SAN
-
LSE
1 stop9h 07m
American Airlines
Deal found 6/13$338
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:22 pm
LSE
-
SAN
1 stop8h 03m
American Airlines
Sat 10/37:27 am
SAN
-
LSE
1 stop7h 25m
American Airlines
Deal found 6/12$369
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:49 pm
LSE
-
SAN
1 stop6h 37m
American Airlines
Tue 7/76:15 am
SAN
-
LSE
1 stop9h 12m
American Airlines
Deal found 6/13$409
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:53 pm
LSE
-
SAN
1 stop7h 33m
American Airlines
Mon 8/36:15 am
SAN
-
LSE
1 stop9h 08m
American Airlines
Deal found 6/11$418
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:20 pm
LSE
-
SAN
1 stop8h 27m
American Airlines
Sun 8/231:11 pm
SAN
-
LSE
1 stop9h 11m
American Airlines
Deal found 6/12$433
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:41 pm
LSE
-
SAN
1 stop7h 45m
American Airlines
Fri 7/176:15 am
SAN
-
LSE
1 stop9h 07m
American Airlines
Deal found 6/12$514

Find flight deals from La Crosse to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$338
(American Airlines)
Provider with most accurate pricing for La Crosse-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for La Crosse-San Diego flights.
Search Deals
From La Crosse to San Diego
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Wed 7/8

5:53 pm-11:26 pm

1 stop7h 33m

San Diego

Wed 7/15

6:15 am-5:23 pm

1 stop9h 08m

$409

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Thu 7/30

5:53 pm-11:26 pm

1 stop7h 33m

San Diego

Mon 8/3

6:15 am-5:23 pm

1 stop9h 08m

$418

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 9/26

12:26 pm-5:29 pm

1 stop7h 03m

San Diego

Sat 10/3

9:46 am-12:20 am

2 stops12h 34m

$428

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Fri 6/26

5:25 pm-11:48 pm

1 stop8h 23m

San Diego

Tue 6/30

12:46 pm-12:19 am

2 stops9h 33m

$531

La CrosseSan Diego

LSE - SAN

LSESAN

La Crosse

Sat 11/14

9:42 am-10:28 pm

2 stops14h 46m

San Diego

Tue 11/17

4:45 pm-8:56 am

1 stop14h 11m

$601

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Sorted by cheapest first

Compare providers for flights from La Crosse to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to San Diego in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on La Crosse-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on La Crosse-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from La Crosse to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from La Crosse with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 14, 2026.
Peruse reviews from past customers who have flown with American Airlines from La Crosse to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,654 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,654 reviews
American Airlines
7.1
Good
11,654 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Food

6.4

Overall

7.1

Crew

7.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from La Crosse to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from La Crosse to San Diego?

    For as low as $338, American Airlines can have you in San Diego from La Crosse in 8h 58m. La Crosse and San Diego are separated by a distance of 1593 mi.

  • What is the cheapest airline to fly from La Crosse to San Diego round-trip?

    According to our current data, American Airlines ($358), offers the cheapest pricing from La Crosse to San Diego.

  • Can I find deals for flights from La Crosse to San Diego that include hotel bookings?

    Yes. In addition to deals on La Crosse to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from La Crosse to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from La Crosse to San Diego.

  • Can I find deals for business class flights from La Crosse to San Diego?

    Yes. Cheapflights offers flight deals from La Crosse to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
National City
Chula Vista
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove

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Top airline flying from La Crosse to San Diego

Discover the top airline that operate flights from La Crosse to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$358Average$554FlexibilityNo cancel feeOn-time71%

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