$211+ Cheap flights from La Crosse to San Diego (LSE - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — SAN
Aug 29 — Sep 51
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from La Crosse to San Diego
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Cheapest flights from La Crosse to San DiegoExplore the most affordable flight options available from La Crosse to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
Explore the most affordable flight options available from La Crosse to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:16 pm
LSE
- SAN
1 stop12h 28m
Multiple Airlines
Tue 8/254:36 pm
SAN
- LSE
2 stops39h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:10 pm
LSE
- SAN
1 stop21h 33m
Multiple Airlines
Fri 8/214:36 pm
SAN
- LSE
2 stops39h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:02 pm
LSE
- SAN
1 stop7h 27m
American Airlines
Sun 10/41:10 pm
SAN
- LSE
1 stop9h 10m
American Airlines
Deal found 7/30![American Airlines logo]()
$448
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:01 pm
LSE
- SAN
1 stop9h 18m
American Airlines
Tue 8/187:24 am
SAN
- LSE
1 stop7h 26m
American Airlines
Deal found 7/30![American Airlines logo]()
$464
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:26 pm
LSE
- SAN
1 stop12h 59m
American Airlines
Tue 9/226:15 am
SAN
- LSE
1 stop16h 05m
American Airlines
Deal found 7/29![American Airlines logo]()
$474
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:20 pm
LSE
- SAN
1 stop17h 38m
American Airlines
Tue 8/257:24 am
SAN
- LSE
1 stop14h 58m
American Airlines
Deal found 7/28![American Airlines logo]()
$476
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:23 pm
LSE
- SAN
1 stop13h 18m
American Airlines
Mon 12/1410:53 pm
SAN
- LSE
1 stop11h 00m
American Airlines
Deal found 7/26![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:20 pm
LSE
- SAN
1 stop8h 27m
American Airlines
Sat 8/151:11 pm
SAN
- LSE
1 stop9h 10m
American Airlines
Deal found 7/27![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
LSE
- SAN
1 stop15h 19m
American Airlines
Fri 9/41:11 pm
SAN
- LSE
1 stop20h 43m
American Airlines
Deal found 7/28![American Airlines logo]()
$504
Best flights from La Crosse to San DiegoDiscover carefully curated flight deals from La Crosse to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
Discover carefully curated flight deals from La Crosse to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:10 pm
LSE
- SAN
1 stop21h 33m
Multiple Airlines
Fri 8/214:36 pm
SAN
- LSE
2 stops39h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3012:02 pm
LSE
- SAN
1 stop11h 28m
American Airlines
Sun 10/410:51 pm
SAN
- LSE
1 stop11h 02m
American Airlines
Deal found 7/29![American Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am
LSE
- SAN
1 stop15h 19m
American Airlines
Fri 9/41:11 pm
SAN
- LSE
1 stop20h 43m
American Airlines
Deal found 7/28![American Airlines logo]()
$504
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:22 pm
LSE
- SAN
1 stop13h 36m
American Airlines
Fri 11/610:40 pm
SAN
- LSE
1 stop17h 36m
American Airlines
Deal found 7/27![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1312:23 pm
LSE
- SAN
1 stop9h 05m
American Airlines
Mon 1/181:12 pm
SAN
- LSE
1 stop8h 47m
American Airlines
Deal found 7/26![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:26 pm
LSE
- SAN
1 stop12h 59m
American Airlines
Sun 9/277:15 pm
SAN
- LSE
2 stops14h 07m
American Airlines
Deal found 7/30![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:23 pm
LSE
- SAN
1 stop13h 18m
American Airlines
Mon 12/149:37 am
SAN
- LSE
2 stops12h 22m
American Airlines
Deal found 7/29![American Airlines logo]()
$571
Last-minute flights from La Crosse to San DiegoDiscover last-minute flight deals from La Crosse to San Diego. Data last updated July 30, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to San Diego. Data last updated July 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:41 pm
LSE
- SAN
1 stop7h 45m
American Airlines
Thu 8/61:11 pm
SAN
- LSE
1 stop9h 11m
American Airlines
Deal found 7/28![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:20 pm
LSE
- SAN
1 stop8h 27m
American Airlines
Sat 8/81:11 pm
SAN
- LSE
1 stop9h 10m
American Airlines
Deal found 7/26![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:20 pm
LSE
- SAN
1 stop8h 27m
American Airlines
Sat 8/151:11 pm
SAN
- LSE
1 stop9h 10m
American Airlines
Deal found 7/27![American Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:20 pm
LSE
- SAN
1 stop8h 27m
American Airlines
Tue 8/189:40 am
SAN
- LSE
2 stops12h 42m
American Airlines
Deal found 7/28![American Airlines logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:10 pm
LSE
- SAN
1 stop21h 33m
Multiple Airlines
Fri 8/214:36 pm
SAN
- LSE
2 stops39h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:01 pm
LSE
- SAN
1 stop9h 18m
American Airlines
Tue 8/187:24 am
SAN
- LSE
1 stop7h 26m
American Airlines
Deal found 7/30![American Airlines logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:16 pm
LSE
- SAN
1 stop12h 28m
Multiple Airlines
Tue 8/254:36 pm
SAN
- LSE
2 stops39h 25m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$332
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:20 pm
LSE
- SAN
1 stop17h 38m
American Airlines
Tue 8/257:24 am
SAN
- LSE
1 stop14h 58m
American Airlines
Deal found 7/28![American Airlines logo]()
$476
One-way flights from La Crosse to San DiegoSearch for one-way flight options from La Crosse to San Diego. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
Search for one-way flight options from La Crosse to San Diego. Find affordable one-way fares based on user searches. Data last updated July 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:46 pm
LSE
- SAN
1 stop14h 43m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$211
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:19 pm
LSE
- SAN
1 stop11h 03m
American Airlines
Deal found 7/28![American Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2012:22 pm
LSE
- SAN
1 stop9h 10m
American Airlines
Deal found 7/30![American Airlines logo]()
$403
Find flight deals from La Crosse to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from La Crosse (LSE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $332 (Kiwi.com) |
One-way from | $211 (Kiwi.com) |
Popular in | September |
Cheapest in | April |
Average price | $409 |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
Use the filters below to find and compare flights from La Crosse to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Fri 8/14
8:10 pm-3:43 pm
1 stop21h 33m
San Diego
Fri 8/21
4:36 pm-10:01 am
2 stops39h 25m
$419
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 9/30
12:02 pm-9:30 pm
1 stop11h 28m
San Diego
Sun 10/4
10:51 pm-11:53 am
1 stop11h 02m
$494
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 9/2
6:00 am-7:19 pm
1 stop15h 19m
San Diego
Fri 9/4
1:11 pm-11:54 am
1 stop20h 43m
$504
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Tue 11/3
12:22 pm-11:58 pm
1 stop13h 36m
San Diego
Fri 11/6
10:40 pm-6:16 pm
1 stop17h 36m
$514
Quickest round-trip
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 1/13
12:23 pm-7:28 pm
1 stop9h 05m
San Diego
Mon 1/18
1:12 pm-11:59 pm
1 stop8h 47m
$520
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Thu 9/24
12:26 pm-11:25 pm
1 stop12h 59m
San Diego
Sun 9/27
7:15 pm-11:22 am
2 stops14h 07m
$530
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Thu 12/10
12:23 pm-11:41 pm
1 stop13h 18m
San Diego
Mon 12/14
9:37 am-11:59 pm
2 stops12h 22m
$571
Cheapest one-way
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Wed 9/2
12:19 pm-9:22 pm
1 stop11h 03m
$352
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Fri 11/20
8:46 pm-7:20 pm
2 stops24h 34m
$363
Quickest one-way
La CrosseSan Diego
LSE - SAN
LSESAN
La Crosse
Fri 11/20
12:22 pm-7:32 pm
1 stop9h 10m
$403
Sorted by cheapest first
Compare providers for flights from La Crosse to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from La Crosse to San Diego in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on La Crosse-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on La Crosse-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from La Crosse-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on La Crosse-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for La Crosse-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from La Crosse to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from La Crosse with our price prediction graph.
LSE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 30, 2026.
Peruse reviews from past customers who have flown with American Airlines from La Crosse to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Boarding
7.5
Overall
7.1
Comfort
7.2
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Food
6.4
Boarding
7.5
Overall
7.1
Comfort
7.2
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreAnonymous,Mar 2026
MIA - SFO
Related info for your journey
Find useful and relevant information for your journey from La Crosse to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
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La Crosse and San Diego flights
Browse other La Crosse and San Diego flight options. Last updated on July 30, 2026.
Other flights from La Crosse
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Top airline flying from La Crosse to San Diego
Discover the top airline that operate flights from La Crosse to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$358 | Average$528 | FlexibilityNo cancel fee | On-time71% |