$121+ Cheap flights from San Diego to La Crosse (SAN - LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — LSE
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Diego to La CrosseExplore the most affordable flight options available from San Diego to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from San Diego to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:15 am -
1 stop8h 37m
Sun 9/275:22 pm -
1 stop8h 03m
Deal found 9/8![American Airlines logo]()
$560
Best flights from San Diego to La CrosseDiscover carefully curated flight deals from San Diego to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from San Diego to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:15 am -
1 stop8h 37m
Sun 9/275:22 pm -
1 stop8h 03m
Deal found 9/8![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/32:04 pm -
1 stop8h 26m
Mon 1/412:49 pm -
2 stops10h 18m
Deal found 9/7![American Airlines logo]()
$972
Last-minute flights from San Diego to La CrosseDiscover last-minute flight deals from San Diego to La Crosse. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to La Crosse. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:15 am -
1 stop8h 37m
Sun 9/275:22 pm -
1 stop8h 03m
Deal found 9/8![American Airlines logo]()
$560
One-way flights from San Diego to La CrosseSearch for one-way flight options from San Diego to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from San Diego to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:01 pm -
1 stop27h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$121
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:32 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:32 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![American Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:25 am -
3 stops48h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$488
Find flight deals from San Diego to La Crosse
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to La Crosse (LSE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $560 (American Airlines) |
One-way from | $121 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from San Diego to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Thu 10/8
2:01 pm-7:16 pm
1 stop27h 15m
La Crosse
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$121
Quickest round-trip
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Tue 9/29
7:32 am-4:52 pm
1 stop7h 20m
La Crosse
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$438
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Fri 9/25
7:32 am-4:52 pm
1 stop7h 20m
La Crosse
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$463
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Tue 9/29
6:25 am-8:56 am
3 stops48h 31m
La Crosse
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$488
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Wed 9/23
6:15 am-4:52 pm
1 stop8h 37m
La Crosse
Sun 9/27
5:22 pm-11:25 pm
1 stop8h 03m
$560
San DiegoLa Crosse
SAN San Diego - LSE La Crosse
SANLSE
San Diego
Sun 1/3
2:04 pm-12:30 am
1 stop8h 26m
La Crosse
Mon 1/4
12:49 pm-9:07 pm
2 stops10h 18m
$972
Sorted by cheapest first
Compare providers for flights from San Diego to La Crosse
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to La Crosse in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-La Crosse flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-La Crosse flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-La Crosse flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-La Crosse flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-La Crosse flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from San Diego with our price prediction graph.
SAN-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing La Crosse
Get insights into the airlines that provide service to La Crosse. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to La Crosse. Reviews last updated September 12, 2026.
Peruse reviews from past customers who have flown with American Airlines from San Diego to La Crosse to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.4
Food
6.4
Overall
7.1
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Boarding
7.4
Food
6.4
Overall
7.1
Entertainment
6.8
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreJeremy,Sep 2025
SAN - PHL
Related info for your journey
Find useful and relevant information for your journey from San Diego to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Top airline flying from San Diego to La Crosse
Discover the top airline that operate flights from San Diego to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$412 | Average$520 | FlexibilityNo cancel fee | On-time71% |