$57+ Cheap flights from Missouri to North Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/6. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CLT
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to North CarolinaExplore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Missouri to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:06 pm
STL
- RDU
1 stop6h 15m
Frontier
Fri 7/312:10 pm
RDU
- STL
1 stop21h 42m
Frontier
Deal found 5/6![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:27 pm
STL
- ORF
1 stop16h 59m
Frontier
Thu 6/1112:21 pm
ORF
- STL
1 stop6h 09m
Frontier
Deal found 5/6![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Fri 6/1212:10 pm
RDU
- STL
1 stop21h 42m
Frontier
Deal found 5/6![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- ORF
1 stop16h 44m
Frontier
Tue 6/912:21 pm
ORF
- STL
1 stop6h 09m
Frontier
Deal found 5/9![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:16 pm
MCI
- RDU
1 stop5h 06m
Frontier
Mon 6/2212:10 pm
RDU
- MCI
1 stop6h 11m
Frontier
Deal found 5/6![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:33 pm
STL
- RDU
1 stop5h 56m
Frontier
Tue 9/112:54 pm
RDU
- STL
1 stop5h 36m
Frontier
Deal found 5/6![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- RDU
1 stop5h 09m
Frontier
Wed 6/1012:10 pm
RDU
- MCI
1 stop6h 11m
Frontier
Deal found 5/10![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- RDU
1 stop4h 51m
Frontier
Tue 6/212:54 pm
RDU
- STL
1 stop5h 39m
Frontier
Deal found 5/8![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Mon 6/812:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 5/7![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Wed 6/106:15 am
RDU
- MCI
1 stop12h 06m
Frontier
Deal found 5/9![Frontier logo]()
$134
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Sun 6/712:54 pm
RDU
- STL
1 stop5h 39m
Frontier
Deal found 5/8![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Fri 6/512:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 5/7![Frontier logo]()
$145
Best flights from Missouri to North CarolinaDiscover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Missouri to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:35 am
STL
- CLT
2 stops8h 10m
Southwest
Wed 6/101:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/6![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:20 am
STL
- CLT
1 stop5h 11m
Delta
Sat 10/177:05 pm
CLT
- STL
1 stop5h 34m
Delta
Deal found 5/8![Delta logo]()
$247
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:12 pm
STL
- ORF
1 stop4h 54m
American Airlines
Tue 6/91:26 pm
ORF
- STL
1 stop6h 34m
American Airlines
Deal found 5/10![American Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:53 am
MCI
- ILM
1 stop6h 07m
United Airlines
Fri 7/37:30 am
ILM
- MCI
2 stops9h 30m
United Airlines
Deal found 5/6![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:40 pm
STL
- CLT
1 stop4h 20m
Southwest
Wed 6/101:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/6![Southwest logo]()
$238
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:30 am
STL
- CLT
1 stop4h 47m
Delta
Sat 8/2211:50 am
CLT
- STL
1 stop3h 43m
Delta
Deal found 5/8![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:35 pm
STL
- TYS
1 stop2h 35m
Southwest
Wed 6/106:55 pm
TYS
- STL
1 stop5h 05m
Southwest
Deal found 5/7![Southwest logo]()
$268
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:51 am
STL
- ORF
1 stop5h 26m
Delta
Mon 6/296:22 pm
ORF
- STL
1 stop4h 56m
Delta
Deal found 5/6![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/252:30 pm
STL
- CLT
1 stop3h 40m
Southwest
Tue 7/71:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/10![Southwest logo]()
$270
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:20 am
STL
- CLT
1 stop4h 38m
Delta
Sun 7/55:30 am
CLT
- STL
1 stop3h 46m
Delta
Deal found 5/10![Delta logo]()
$286
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
STL
- RDU
2 stops7h 08m
United Airlines
Wed 6/1010:00 am
RDU
- STL
1 stop6h 46m
United Airlines
Deal found 5/10![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:20 pm
STL
- ORF
1 stop5h 15m
Southwest
Mon 7/276:10 pm
ORF
- STL
1 stop6h 00m
Southwest
Deal found 5/8![Southwest logo]()
$275
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
STL
- CLT
1 stop4h 47m
Delta
Mon 8/105:30 am
CLT
- STL
1 stop5h 24m
Delta
Deal found 5/10![Delta logo]()
$286
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:29 pm
STL
- ORF
1 stop6h 28m
United Airlines
Wed 6/1010:48 am
ORF
- STL
1 stop5h 58m
United Airlines
Deal found 5/10![United Airlines logo]()
$365
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:30 pm
STL
- ORF
1 stop7h 35m
Southwest
Sat 6/276:00 am
ORF
- STL
1 stop5h 40m
Southwest
Deal found 5/7![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:05 pm
STL
- TYS
1 stop3h 56m
Delta
Wed 6/105:40 am
TYS
- STL
1 stop5h 06m
Delta
Deal found 5/10![Delta logo]()
$295
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:00 am
STL
- ILM
1 stop6h 48m
United Airlines
Tue 8/187:00 am
ILM
- STL
2 stops9h 38m
United Airlines
Deal found 5/9![United Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:15 pm
STL
- CLT
2 stops8h 35m
Southwest
Sat 8/151:00 pm
CLT
- STL
1 stop6h 15m
Southwest
Deal found 5/10![Southwest logo]()
$285
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 pm
STL
- ILM
1 stop5h 09m
Delta
Wed 6/106:50 pm
ILM
- STL
1 stop6h 06m
Delta
Deal found 5/6![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/161:13 pm
STL
- RDU
2 stops9h 31m
United Airlines
Tue 6/236:00 am
RDU
- STL
2 stops10h 46m
United Airlines
Deal found 5/10![United Airlines logo]()
$376
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:15 am
STL
- RDU
Nonstop1h 50m
Southwest
Wed 6/106:00 am
RDU
- STL
1 stop6h 30m
Southwest
Deal found 5/6![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:00 am
STL
- CLT
1 stop4h 03m
Delta
Tue 8/1811:50 am
CLT
- STL
1 stop3h 43m
Delta
Deal found 5/8![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:30 pm
STL
- RDU
1 stop5h 05m
Southwest
Tue 6/166:35 am
RDU
- STL
Nonstop2h 05m
Southwest
Deal found 5/9![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- ILM
1 stop6h 37m
United Airlines
Sat 8/294:44 pm
ILM
- STL
1 stop6h 16m
United Airlines
Deal found 5/10![United Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:40 am
STL
- CLT
2 stops7h 55m
Southwest
Mon 6/294:00 pm
CLT
- STL
2 stops7h 50m
Southwest
Deal found 5/6![Southwest logo]()
$290
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:00 am
STL
- MYR
1 stop7h 12m
United Airlines
Wed 6/106:50 pm
MYR
- STL
1 stop5h 45m
United Airlines
Deal found 5/7![United Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:38 am
MCI
- ILM
1 stop7h 03m
Delta
Wed 7/85:48 am
ILM
- MCI
1 stop6h 23m
Delta
Deal found 5/10![Delta logo]()
$334
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/314:40 pm
STL
- CLT
1 stop4h 50m
Southwest
Wed 6/37:35 am
CLT
- STL
1 stop4h 55m
Southwest
Deal found 5/7![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:55 pm
MCI
- RDU
Nonstop2h 31m
Delta
Tue 7/75:20 am
RDU
- MCI
1 stop5h 04m
Delta
Deal found 5/6![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:53 am
MCI
- ILM
1 stop6h 07m
United Airlines
Wed 7/87:30 am
ILM
- MCI
2 stops11h 06m
United Airlines
Deal found 5/6![United Airlines logo]()
$424
Last-minute flights from Missouri to North CarolinaDiscover last-minute flight deals from Missouri to North Carolina. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to North Carolina. Data last updated May 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:33 pm
STL
- RDU
1 stop4h 51m
Frontier
Tue 6/212:54 pm
RDU
- STL
1 stop5h 39m
Frontier
Deal found 5/8![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- ORF
1 stop16h 44m
Frontier
Tue 6/912:21 pm
ORF
- STL
1 stop6h 09m
Frontier
Deal found 5/9![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Mon 6/812:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 5/7![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Wed 6/106:15 am
RDU
- MCI
1 stop12h 06m
Frontier
Deal found 5/9![Frontier logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Fri 6/512:33 pm
RDU
- MCI
1 stop5h 56m
Frontier
Deal found 5/7![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- RDU
1 stop5h 09m
Frontier
Wed 6/1012:10 pm
RDU
- MCI
1 stop6h 11m
Frontier
Deal found 5/10![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:33 pm
STL
- RDU
1 stop12h 31m
Frontier
Sun 6/712:54 pm
RDU
- STL
1 stop21h 01m
Frontier
Deal found 5/8![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Fri 6/1212:10 pm
RDU
- STL
1 stop21h 42m
Frontier
Deal found 5/6![Frontier logo]()
$124
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Sun 6/712:54 pm
RDU
- STL
1 stop5h 39m
Frontier
Deal found 5/8![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:27 pm
STL
- ORF
1 stop16h 59m
Frontier
Thu 6/1112:21 pm
ORF
- STL
1 stop6h 09m
Frontier
Deal found 5/6![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/136:16 pm
MCI
- RDU
1 stop5h 06m
Frontier
Mon 6/2212:10 pm
RDU
- MCI
1 stop6h 11m
Frontier
Deal found 5/6![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/265:06 pm
STL
- RDU
1 stop6h 15m
Frontier
Fri 7/312:10 pm
RDU
- STL
1 stop21h 42m
Frontier
Deal found 5/6![Frontier logo]()
$121
One-way flights from Missouri to North CarolinaSearch for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Missouri to North Carolina. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:27 pm
STL
- ORF
1 stop16h 44m
Frontier
Deal found 5/9![Frontier logo]()
$57
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- ORF
1 stop16h 44m
Frontier
Deal found 5/10![Frontier logo]()
$59
This Trip.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:24 pm
MCI
- RDU
1 stop16h 35m
Frontier
Deal found 5/6![Frontier logo]()
$59
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:33 pm
STL
- ORF
1 stop15h 48m
Frontier
Deal found 5/10![Frontier logo]()
$60
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- RDU
1 stop5h 57m
Frontier
Deal found 5/7![Frontier logo]()
$62
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:33 pm
STL
- ORF
1 stop15h 38m
Frontier
Deal found 5/6![Frontier logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:24 pm
MCI
- RDU
1 stop12h 40m
Frontier
Deal found 5/6![Frontier logo]()
$63
This Trip.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:27 pm
STL
- RDU
1 stop6h 06m
Frontier
Deal found 5/6![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/34:52 pm
STL
- RDU
1 stop18h 02m
Frontier
Deal found 5/10![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:33 pm
STL
- ORF
1 stop15h 38m
Frontier
Deal found 5/10![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:16 pm
MCI
- RDU
1 stop5h 05m
Frontier
Deal found 5/10![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- RDU
1 stop5h 09m
Frontier
Deal found 5/10![Frontier logo]()
$66
Find flight deals from Missouri to North Carolina
Keep the following information in mind while searching for Missouri to North Carolina flight deals. Data was last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $121 (Kiwi.com) |
One-way from | $57 (Trip.com) |
Popular in | August |
Cheapest in | October |
Average price | $384 |
Good round-trip deal | $341 or less |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Missouri to North Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/3
11:35 am-8:45 pm
2 stops8h 10m
Charlotte Douglas
Wed 6/10
1:25 pm-2:25 pm
Nonstop2h 00m
$232
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 6/1
4:40 pm-10:00 pm
1 stop4h 20m
Charlotte Douglas
Wed 6/10
1:25 pm-2:25 pm
Nonstop2h 00m
$238
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sat 10/17
7:20 am-1:31 pm
1 stop5h 11m
Charlotte Douglas
Sat 10/17
7:05 pm-11:39 pm
1 stop5h 34m
$247
St. LouisKnoxville
STL - TYS
STLTYS
Lambert-St Louis
Mon 6/8
5:35 pm-9:10 pm
1 stop2h 35m
Knoxville McGhee Tyson
Wed 6/10
6:55 pm-11:00 pm
1 stop5h 05m
$268
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 8/13
6:30 am-12:17 pm
1 stop4h 47m
Charlotte Douglas
Sat 8/22
11:50 am-2:33 pm
1 stop3h 43m
$269
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 6/25
2:30 pm-7:10 pm
1 stop3h 40m
Charlotte Douglas
Tue 7/7
1:25 pm-2:25 pm
Nonstop2h 00m
$270
St. LouisNorfolk
STL - ORF
STLORF
Lambert-St Louis
Thu 6/25
10:51 am-5:17 pm
1 stop5h 26m
Norfolk
Mon 6/29
6:22 pm-10:18 pm
1 stop4h 56m
$275
St. LouisNorfolk
STL - ORF
STLORF
Lambert-St Louis
Thu 7/23
5:20 pm-11:35 pm
1 stop5h 15m
Norfolk
Mon 7/27
6:10 pm-11:10 pm
1 stop6h 00m
$275
St. LouisNorfolk
STL - ORF
STLORF
Lambert-St Louis
Sat 6/20
2:30 pm-11:05 pm
1 stop7h 35m
Norfolk
Sat 6/27
6:00 am-10:40 am
1 stop5h 40m
$280
St. LouisNorfolk
STL - ORF
STLORF
Lambert-St Louis
Sat 6/6
6:12 pm-12:06 am
1 stop4h 54m
Norfolk
Tue 6/9
1:26 pm-7:00 pm
1 stop6h 34m
$285
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from Missouri with our price prediction graph.
STL-RDU
STL-ORF
MCI-RDU
STL-TYS
STL-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to North Carolina
USMO-USNC
STL-RDU
STL-ORF
MCI-RDU
STL-TYS
How far ahead should I book a flight from Missouri to North Carolina?
To ensure you get the cheapest price possible for a flight from Missouri to North Carolina, you should look to book at least 64 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Missouri to North Carolina?
Currently, December is the cheapest month in which you can book a flight from Missouri to North Carolina (average of $82). Flying from Missouri to North Carolina in March is currently the most expensive (average of $194). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to NC?
Find hourly flight availability from Missouri to North Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 11, 2026.
It’s optimal to fly from Missouri to North Carolina in the afternoon. By choosing this option you can save up to 14% on the cost of your flight, compared to a flight in the morning.
What is the cheapest day to fly from Missouri to North Carolina?
Use this chart to determine the cheapest time to fly round-trip from Missouri to North Carolina. Price data was last updated on May 9, 2026.
Travelers seeking maximum savings on their Missouri to North Carolina flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Missouri to North Carolina
Explore weekly flight availability from Missouri to North Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 11, 2026.
The most flights from USMO to USNC are scheduled on a Sunday (7 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Missouri to North Carolina?
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated May 11, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from Missouri to North Carolina have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to North Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to North Carolina by cabin class
Find flights from Missouri to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and North Carolina flights
Browse other Missouri and North Carolina flight options. Last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from North Carolina
Find the right flight back to Missouri after your stay in North Carolina
Missouri to North Carolina flights
Consider these flights traveling from Missouri to North Carolina.
Top 5 airlines flying from Missouri to North Carolina
Discover the top 5 airlines that operate flights from Missouri to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$90 | Average$196 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$128 | Average$361 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$134 | Average$403 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$187 | Average$373 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$192 | Average$385 | FlexibilityNo cancel fee | On-time71% |