Which airport typically offers the quickest layover for flights from Des Moines to Los Angeles?

Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 0h 54m.

What’s the cheapest layover airport for flights from Des Moines to Los Angeles?

St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $284.

What’s the top layover airport for flights from Des Moines to Los Angeles?

St. Louis (STL) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Los Angeles on Cheapflights.

What’s the fastest layover option from Des Moines to Los Angeles?

Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 5h 34m.

How popular is this Des Moines to Los Angeles flight route?

This flight path from Des Moines to Los Angeles was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Des Moines to Los Angeles?

There are many flights that can get you from Des Moines to Los Angeles in 4h 25m. Fly via American Airlines or Delta to get the fastest option. The distance between Des Moines and Los Angeles is about 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?

According to our current data, Allegiant Air ($127), Frontier ($149), and Delta ($236) offers the cheapest pricing from Des Moines to Los Angeles. You may be able to fly from Des Moines to Los Angeles for 66% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Des Moines to Los Angeles one-way?

One-way options have recently been found by users for as low as $60 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $73 and Delta from $110 one-way.

Weekly flight availability from Des Moines to Los Angeles

The most flights from DSM to LAX are scheduled on a Tuesday (2 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Los Angeles ranges from 0.0 - 3.4 inches per month. February is typically the wettest month, when rainfall can reach 3.4 in. July is typically the driest time to visit Los Angeles when rainfall is around 0.0 in.

If weather is an important factor for your trip to Los Angeles, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What are the cheapest flights from Des Moines to Los Angeles?

On average you can expect to pay $325 for a flight from Des Moines to Los Angeles. The cheapest flight overall is $122 while the most popular route, (Des Moines - Los Angeles) is currently priced at $222.

What are the most popular airlines that fly from Des Moines to Los Angeles?

Consider American Airlines, United Airlines or Southwest when booking your flight. These represent the most popular airlines when flying from Des Moines to Los Angeles.

Most accurate provider : When it comes to deals on Des Moines-Los Angeles flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Los Angeles flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Los Angeles flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Los Angeles flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Los Angeles flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Des Moines to Los Angeles?

You will need to book a flight from Des Moines to Los Angeles if you want to fly from Des Moines to Los Angeles. At least 6 different airlines have flights from Des Moines (DSM) to Los Angeles (LAX) on a regular basis. There is 1 flight to Los Angeles from the Des Moines airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DSM to LAX to be around 4h 01m.

Can I find deals for flights from Des Moines to Los Angeles that include hotel bookings?

Yes. In addition to deals on Des Moines to Los Angeles flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Los Angeles?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Los Angeles.

Can I find deals for business class flights from Des Moines to Los Angeles?

Yes. Cheapflights offers flight deals from Des Moines to Los Angeles by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$80+ Flights from Des Moines to Los Angeles

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Des Moines to Los Angeles are usually found in May or January, booked 80 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Los Angeles

Cheapest flights from Des Moines to Los Angeles
Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Wed 12/248:31 amDSM - LAX

2 stops25h 11mMultiple Airlines

Mon 12/295:59 pmLAX - DSM

1 stop19h 32mMultiple Airlines

Deal found 12/11

$305

Fri 12/197:54 pmDSM - LAX

1 stop18h 34mMultiple Airlines

Thu 1/156:14 pmLAX - DSM

1 stop21h 10mMultiple Airlines

Deal found 12/11

$326

Mon 12/228:29 pmDSM - LAX

1 stop6h 01mFrontier

Mon 1/126:26 amLAX - DSM

1 stop10h 56mFrontier

Deal found 12/10

$362

Sat 12/208:29 pmDSM - LAX

1 stop6h 01mFrontier

Mon 1/56:34 amLAX - DSM

1 stop11h 10mFrontier

Deal found 12/11

$363

Fri 12/193:15 pmDSM - LAX

Nonstop4h 07mAmerican Airlines

Thu 1/159:15 amLAX - DSM

Nonstop3h 35mAmerican Airlines

Deal found 12/11

$373

Sun 12/2110:17 amDSM - LAX

3 stops31h 57mMultiple Airlines

Sun 12/2810:03 pmLAX - DSM

1 stop11h 53mMultiple Airlines

Deal found 12/11

$377

Wed 12/313:00 pmDSM - LAX

1 stop7h 31mMultiple Airlines

Sun 1/43:30 pmLAX - DSM

2 stops26h 14mMultiple Airlines

Deal found 12/9

$379

Mon 12/227:54 pmDSM - LAX

1 stop13h 24mMultiple Airlines

Mon 1/126:26 amLAX - DSM

1 stop10h 56mMultiple Airlines

Deal found 12/9

$381

Sat 12/208:29 pmDSM - LAX

2 stops15h 44mFrontier

Sun 1/182:11 pmLAX - DSM

1 stop27h 12mFrontier

Deal found 12/11

$385

Sat 12/205:06 pmDSM - LAX

1 stop7h 49mUnited Airlines

Sat 1/1712:30 amLAX - DSM

1 stop8h 25mUnited Airlines

Deal found 12/11

$392

Best flights from Des Moines to Los Angeles
Discover carefully curated flight deals from Des Moines to Los Angeles that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Mon 1/268:30 amDSM - LAX

1 stop8h 42mMultiple Airlines

Thu 1/298:20 amLAX - DSM

3 stops35h 01mMultiple Airlines

Deal found 12/11

$288

Fri 5/83:20 pmDSM - LAX

Nonstop4h 25mAmerican Airlines

Tue 5/129:05 amLAX - DSM

Nonstop3h 40mAmerican Airlines

Deal found 12/11

$294

Wed 1/2112:25 pmDSM - LAX

1 stop10h 35mDelta

Sat 1/2410:20 pmLAX - DSM

1 stop9h 21mDelta

Deal found 12/10

$295

Tue 1/68:35 amDSM - LAX

2 stops9h 40mSouthwest

Sat 1/105:25 amLAX - DSM

1 stop4h 50mSouthwest

Deal found 12/9

$300

Sat 1/246:24 amDSM - LAX

1 stop10h 22mDelta

Sat 1/3110:20 pmLAX - DSM

1 stop9h 21mDelta

Deal found 12/10

$295

Wed 1/213:25 pmDSM - LAX

Nonstop4h 01mAmerican Airlines

Sun 1/256:38 amLAX - DSM

1 stop5h 10mAmerican Airlines

Deal found 12/11

$304

Wed 1/2110:30 amDSM - LAX

1 stop8h 19mDelta

Sun 1/2510:55 pmLAX - DSM

1 stop9h 46mDelta

Deal found 12/10

$314

Last-minute flights from Des Moines to Los Angeles
Discover last-minute flight deals from Des Moines to Los Angeles. Data last updated December 12, 2025 and is based on user searches.

Tue 1/63:25 pmDSM - LAX

Nonstop4h 01mAmerican Airlines

Sat 1/109:15 amLAX - DSM

Nonstop3h 35mAmerican Airlines

Deal found 12/10

$275

Tue 1/68:35 amDSM - LAX

2 stops9h 40mSouthwest

Sat 1/105:25 amLAX - DSM

1 stop4h 50mSouthwest

Deal found 12/9

$300

Sun 1/183:25 pmDSM - LAX

Nonstop4h 01mAmerican Airlines

Sat 1/249:15 amLAX - DSM

Nonstop3h 35mAmerican Airlines

Deal found 12/11

$294

Wed 1/213:25 pmDSM - LAX

Nonstop4h 01mAmerican Airlines

Sat 1/246:25 amLAX - DSM

1 stop7h 59mAmerican Airlines

Deal found 12/11

$285

Sat 1/243:25 pmDSM - LAX

Nonstop4h 01mAmerican Airlines

Sat 1/319:15 amLAX - DSM

Nonstop3h 35mAmerican Airlines

Deal found 12/10

$276

Sat 1/2412:25 pmDSM - LAX

1 stop8h 27mDelta

Sat 1/3110:20 pmLAX - DSM

1 stop9h 21mDelta

Deal found 12/9

$295

One-way flights from Des Moines to Los Angeles
Search for one-way flight options from Des Moines to Los Angeles. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Mon 1/128:17 pmDSM - LAX

1 stop19h 10mFrontier

Deal found 12/11

$80

Mon 3/98:21 pmDSM - LAX

1 stop5h 56mFrontier

Deal found 12/11

$91

Fri 1/98:17 pmDSM - LAX

1 stop26h 11mFrontier

Deal found 12/11

$104

Mon 2/98:30 amDSM - LAX

1 stop8h 42mMultiple Airlines

Deal found 12/9

$110

Wed 3/118:21 pmDSM - LAX

1 stop5h 56mFrontier

Deal found 12/11

$112

Sun 2/88:30 amDSM - LAX

1 stop27h 55mMultiple Airlines

Deal found 12/11

$115

Thu 2/127:32 pmDSM - LAX

1 stop14h 14mFrontier

Deal found 12/11

$125

Thu 1/88:30 amDSM - LAX

1 stop8h 42mMultiple Airlines

Deal found 12/11

$126

Sun 1/114:30 pmDSM - LAX

2 stops17h 49mMultiple Airlines

Deal found 12/11

$127

Find flight deals from Des Moines to Los Angeles

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$275 (American Airlines)
One-way from	$80 (Kiwi.com)
Popular in	March
Cheapest in	May
Average price	$434
Good round-trip deal	$294 or less
Good one-way deal	$203 or less

Provider with most accurate pricing for Des Moines-Los Angeles flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.

Search Deals

From Des Moines to Los Angeles

Search Deals

One-way flight from Des Moines to Los Angeles

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($25 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Des Moines to Los Angeles.

Search Deals

Price to beat on a one-way flight from Des Moines to Los Angeles.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Los Angeles that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 1/26

8:30 am-3:12 pm

1 stop8h 42m

Los Angeles

Thu 1/29

8:20 am-9:21 pm

3 stops35h 01m

$288

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 5/8

3:20 pm-5:45 pm

Nonstop4h 25m

Los Angeles

Tue 5/12

9:05 am-2:45 pm

Nonstop3h 40m

$294

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

12:25 pm-9:00 pm

1 stop10h 35m

Los Angeles

Sat 1/24

10:20 pm-9:41 am

1 stop9h 21m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/24

6:24 am-2:46 pm

1 stop10h 22m

Los Angeles

Sat 1/31

10:20 pm-9:41 am

1 stop9h 21m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 1/6

8:35 am-4:15 pm

2 stops9h 40m

Los Angeles

Sat 1/10

5:25 am-12:15 pm

1 stop4h 50m

$300

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

3:25 pm-5:26 pm

Nonstop4h 01m

Los Angeles

Sun 1/25

6:38 am-1:48 pm

1 stop5h 10m

$304

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

10:30 am-4:49 pm

1 stop8h 19m

Los Angeles

Sun 1/25

10:55 pm-10:41 am

1 stop9h 46m

$314

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 3/7

8:21 pm-12:17 am

1 stop5h 56m

$91

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Mon 3/9

8:21 pm-12:17 am

1 stop5h 56m

$91

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 1/9

8:17 pm-8:28 pm

1 stop26h 11m

$104

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 17 results

Compare providers for flights from Des Moines to Los Angeles

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Los Angeles in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
JustAirTicket	Price Accuracy-	Trust Score*1 star
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Los Angeles flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Los Angeles flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Los Angeles flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Los Angeles flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Los Angeles flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Los Angeles

Have a flexible travel schedule? Discover the best time to fly to Los Angeles from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Los Angeles

Prices

Airlines

How far ahead should I book a flight from Des Moines to Los Angeles?

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Los Angeles. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines to Los Angeles?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Los Angeles (average of $105). Flying from Des Moines to Los Angeles in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LAX?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Los Angeles in the morning. If you’re flexible enough to do this you can expect to save up to 53% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Des Moines to Los Angeles?

Travelers seeking maximum savings on their Des Moines to Los Angeles flight should consider departing on Friday evenings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Los Angeles

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Des Moines to Los Angeles by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,008 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,095 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,084 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Des Moines to Los Angeles?
You will need to book a flight from Des Moines to Los Angeles if you want to fly from Des Moines to Los Angeles. At least 6 different airlines have flights from Des Moines (DSM) to Los Angeles (LAX) on a regular basis. There is 1 flight to Los Angeles from the Des Moines airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DSM to LAX to be around 4h 01m.
How popular is this Des Moines to Los Angeles flight route?
This flight path from Des Moines to Los Angeles was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Des Moines to Los Angeles?
There are many flights that can get you from Des Moines to Los Angeles in 4h 25m. Fly via American Airlines or Delta to get the fastest option. The distance between Des Moines and Los Angeles is about 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?
According to our current data, Allegiant Air ($127), Frontier ($149), and Delta ($236) offers the cheapest pricing from Des Moines to Los Angeles. You may be able to fly from Des Moines to Los Angeles for 66% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Des Moines to Los Angeles one-way?
One-way options have recently been found by users for as low as $60 on Allegiant Air. Other airlines that offer cheap prices include Frontier from $73 and Delta from $110 one-way.
What are the cheapest flights from Des Moines to Los Angeles?
On average you can expect to pay $325 for a flight from Des Moines to Los Angeles. The cheapest flight overall is $122 while the most popular route, (Des Moines - Los Angeles) is currently priced at $222.
Can I find deals for flights from Des Moines to Los Angeles that include hotel bookings?
Yes. In addition to deals on Des Moines to Los Angeles flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Los Angeles?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Los Angeles.
Can I find deals for business class flights from Des Moines to Los Angeles?
Yes. Cheapflights offers flight deals from Des Moines to Los Angeles by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Los Angeles?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Los Angeles (average of $105). Flying from Des Moines to Los Angeles in December is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Los Angeles

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$127	Average$176	FlexibilityNo cancel fee	On-time88%
Frontier	Cheapest$149	Average$234	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$239	Average$342	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$256	Average$374	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$284	Average$383	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$294	Average$417	FlexibilityNo cancel fee	On-time63%

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$80+ Cheap flights from Des Moines to Los Angeles (DSM - LAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Los Angeles with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Los Angeles are usually found in May or January, booked 80 days in advance, depart on a Friday or Wednesday and return on a Tuesday

Cheap flight deals from Des Moines to Los Angeles

Cheapest flights from Des Moines to Los AngelesExplore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Des Moines to Los Angeles

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Los Angeles that are best for you.

Compare providers for flights from Des Moines to Los Angeles

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Los Angeles in December.

Best time to book a flight from Des Moines to Los Angeles

Have a flexible travel schedule? Discover the best time to fly to Los Angeles from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Los Angeles

How far ahead should I book a flight from Des Moines to Los Angeles?

What is the cheapest month to book a flight from Des Moines to Los Angeles?

What is the cheapest time of day to fly from DSM to LAX?

What is the cheapest day to fly from Des Moines to Los Angeles?

Weekly flight availability from Des Moines to Los Angeles

What’s the top layover airport for flights from Des Moines to Los Angeles?

What’s the cheapest layover airport for flights from Des Moines to Los Angeles?

What’s the fastest layover option from Des Moines to Los Angeles?

Which airport typically offers the quickest layover for flights from Des Moines to Los Angeles?

Reviews of airlines servicing Los Angeles

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Des Moines to Los Angeles by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Los Angeles. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Des Moines to Los Angeles?

How popular is this Des Moines to Los Angeles flight route?

How long is the flight from Des Moines to Los Angeles?

What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?

What are the cheapest airlines to fly from Des Moines to Los Angeles one-way?

What are the cheapest flights from Des Moines to Los Angeles?

Can I find deals for flights from Des Moines to Los Angeles that include hotel bookings?

How can I find direct flights from Des Moines to Los Angeles?

Can I find deals for business class flights from Des Moines to Los Angeles?

What is the cheapest month to book a flight from Des Moines to Los Angeles?

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Alternative routes for Des Moines to Los Angeles

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Top 6 airlines flying from Des Moines to Los Angeles

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Cheapest flights from Des Moines to Los Angeles
Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.