What’s the top layover airport for flights from Des Moines to Los Angeles?

St. Louis (STL) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Los Angeles on Cheapflights.

Which airport typically offers the quickest layover for flights from Des Moines to Los Angeles?

Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 0h 54m.

What’s the fastest layover option from Des Moines to Los Angeles?

Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 5h 34m.

What’s the cheapest layover airport for flights from Des Moines to Los Angeles?

St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $284.

How popular is this Des Moines to Los Angeles flight route?

This flight path from Des Moines to Los Angeles was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Des Moines to Los Angeles?

There are many flights that can get you from Des Moines to Los Angeles in 5h 36m. Fly via Delta or United Airlines to get the fastest option. The distance between Des Moines and Los Angeles is about 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?

According to our current data, Allegiant Air ($127), Frontier ($149), and Delta ($239) offers the cheapest pricing from Des Moines to Los Angeles. You may be able to fly from Des Moines to Los Angeles for 67% less than the average price by searching for these airlines.

Weekly flight availability from Des Moines to Los Angeles

The most flights from DSM to LAX are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Los Angeles ranges from 0.0 - 3.4 inches per month. February is typically the wettest month, when rainfall can reach 3.4 in. July is typically the driest time to visit Los Angeles when rainfall is around 0.0 in.

If weather is an important factor for your trip to Los Angeles, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

What are the cheapest flights from Des Moines to Los Angeles?

On average you can expect to pay $933 for a flight from Des Moines to Los Angeles. The cheapest flight overall is $137 while the most popular route, (Des Moines - Los Angeles) is currently priced at $158.

What are the most popular airlines that fly from Des Moines to Los Angeles?

Consider American Airlines, United Airlines or Southwest when booking your flight. These represent the most popular airlines when flying from Des Moines to Los Angeles.

Most accurate provider : When it comes to deals on Des Moines-Los Angeles flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Los Angeles flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Los Angeles flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Los Angeles flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Los Angeles flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airports do I use to fly from Des Moines to Los Angeles?

You will need to book a flight from Des Moines to Los Angeles if you want to fly from Des Moines to Los Angeles. At least 6 different airlines have flights from Des Moines (DSM) to Los Angeles (LAX) on a regular basis. There is 1 flight to Los Angeles from the Des Moines airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DSM to LAX to be around 3h 50m.

Can I find deals for flights from Des Moines to Los Angeles that include hotel bookings?

Yes. In addition to deals on Des Moines to Los Angeles flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Los Angeles?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Los Angeles.

Can I find deals for business class flights from Des Moines to Los Angeles?

Yes. Cheapflights offers flight deals from Des Moines to Los Angeles by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$61+ Flights from Des Moines to Los Angeles

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

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Cheapflights Tip: The best prices from Des Moines to Los Angeles are usually found in May or July, booked 80 days in advance, depart on a Monday or Friday and return on a Tuesday

Find flight deals from Des Moines to Los Angeles

Cheapest flights from Des Moines to Los Angeles
Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Mon 12/157:58 pmDSM - LAX

1 stop24h 40mMultiple Airlines

Thu 12/189:58 pmLAX - DSM

1 stop19h 06mMultiple Airlines

Deal found 10/25

$185

Fri 12/57:58 pmDSM - LAX

1 stop24h 40mFrontier

Mon 12/86:40 amLAX - DSM

1 stop10h 23mFrontier

Deal found 10/26

$190

Wed 12/108:00 amDSM - LAX

2 stops25h 42mMultiple Airlines

Thu 12/118:51 pmLAX - DSM

1 stop20h 12mMultiple Airlines

Deal found 10/27

$197

Mon 11/243:48 pmDSM - LAX

1 stop23h 05mMultiple Airlines

Fri 12/56:40 amLAX - DSM

1 stop10h 23mMultiple Airlines

Deal found 10/26

$200

Thu 12/42:56 pmDSM - LAX

2 stops32h 15mMultiple Airlines

Mon 12/86:40 amLAX - DSM

1 stop10h 23mMultiple Airlines

Deal found 10/25

$202

Wed 11/262:00 pmDSM - LAX

1 stop26h 03mFrontier

Thu 12/48:51 pmLAX - DSM

1 stop20h 12mFrontier

Deal found 10/26

$204

Mon 11/102:32 pmDSM - LAX

1 stop24h 46mMultiple Airlines

Fri 11/149:04 amLAX - DSM

1 stop11h 36mMultiple Airlines

Deal found 10/26

$209

Mon 11/102:32 pmDSM - LAX

1 stop24h 46mFrontier

Wed 11/122:48 pmLAX - DSM

1 stop21h 08mFrontier

Deal found 10/25

$212

Mon 12/228:29 pmDSM - LAX

1 stop13h 13mMultiple Airlines

Thu 1/86:00 amLAX - DSM

1 stop7h 40mMultiple Airlines

Deal found 10/26

$213

Fri 12/57:58 pmDSM - LAX

1 stop6h 31mMultiple Airlines

Sat 12/63:30 pmLAX - DSM

2 stops28h 06mMultiple Airlines

Deal found 10/25

$216

Best flights from Des Moines to Los Angeles
Discover carefully curated flight deals from Des Moines to Los Angeles that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 27, 2025.

Wed 1/215:16 pmDSM - LAX

1 stop8h 39mDelta

Sat 1/2410:55 pmLAX - DSM

1 stop9h 46mDelta

Deal found 10/25

$295

Wed 12/105:45 amDSM - LAX

1 stop5h 36mUnited Airlines

Wed 12/1012:25 amLAX - DSM

1 stop8h 04mUnited Airlines

Deal found 10/27

$295

Sat 1/175:45 amDSM - LAX

1 stop6h 05mSouthwest

Sat 1/315:25 amLAX - DSM

1 stop5h 15mSouthwest

Deal found 10/26

$295

Sat 1/171:35 pmDSM - LAX

1 stop5h 50mUnited Airlines

Fri 1/3012:30 amLAX - DSM

1 stop8h 25mUnited Airlines

Deal found 10/26

$295

Sat 12/611:01 amDSM - LAX

1 stop5h 58mDelta

Sat 12/1310:59 pmLAX - DSM

1 stop9h 39mDelta

Deal found 10/26

$295

Sat 1/107:50 amDSM - LAX

1 stop7h 40mUnited Airlines

Sat 1/171:04 pmLAX - DSM

1 stop5h 30mUnited Airlines

Deal found 10/25

$295

Wed 12/102:16 pmDSM - LAX

1 stop9h 33mDelta

Wed 12/178:25 amLAX - DSM

1 stop7h 22mDelta

Deal found 10/25

$295

Wed 12/35:15 pmDSM - LAX

1 stop5h 46mUnited Airlines

Fri 12/1212:25 amLAX - DSM

1 stop8h 28mUnited Airlines

Deal found 10/26

$295

Tue 1/612:04 pmDSM - LAX

1 stop10h 58mDelta

Tue 1/137:20 amLAX - DSM

1 stop7h 09mDelta

Deal found 10/26

$295

Last-minute flights from Des Moines to Los Angeles
Discover last-minute flight deals from Des Moines to Los Angeles. Data last updated October 27, 2025 and is based on user searches.

Sun 11/92:17 pmDSM - LAX

1 stop19h 57mMultiple Airlines

Wed 11/123:27 pmLAX - DSM

1 stop27h 45mMultiple Airlines

Deal found 10/25

$245

Mon 11/102:32 pmDSM - LAX

1 stop24h 46mMultiple Airlines

Fri 11/149:04 amLAX - DSM

1 stop11h 36mMultiple Airlines

Deal found 10/26

$209

Mon 11/102:32 pmDSM - LAX

1 stop24h 46mFrontier

Wed 11/122:48 pmLAX - DSM

1 stop21h 08mFrontier

Deal found 10/25

$212

Fri 11/142:34 pmDSM - LAX

1 stop24h 44mFrontier

Sun 11/166:44 amLAX - DSM

1 stop29h 03mFrontier

Deal found 10/25

$225

Fri 11/142:34 pmDSM - LAX

1 stop24h 44mMultiple Airlines

Mon 11/179:04 amLAX - DSM

1 stop11h 36mMultiple Airlines

Deal found 10/25

$246

Mon 11/243:48 pmDSM - LAX

1 stop23h 05mMultiple Airlines

Fri 12/56:40 amLAX - DSM

1 stop10h 23mMultiple Airlines

Deal found 10/26

$200

Mon 11/246:40 amDSM - LAX

2 stops13h 43mMultiple Airlines

Thu 12/48:51 pmLAX - DSM

1 stop20h 12mMultiple Airlines

Deal found 10/26

$229

Tue 11/257:30 amDSM - LAX

2 stops14h 17mMultiple Airlines

Thu 12/48:51 pmLAX - DSM

1 stop20h 12mMultiple Airlines

Deal found 10/26

$240

Wed 11/262:00 pmDSM - LAX

1 stop26h 03mFrontier

Thu 12/48:51 pmLAX - DSM

1 stop20h 12mFrontier

Deal found 10/26

$204

Wed 11/262:00 pmDSM - LAX

1 stop26h 03mFrontier

Fri 12/56:40 amLAX - DSM

1 stop10h 23mFrontier

Deal found 10/26

$221

Wed 11/262:00 pmDSM - LAX

1 stop26h 03mMultiple Airlines

Wed 12/33:30 pmLAX - DSM

1 stop22h 01mMultiple Airlines

Deal found 10/26

$241

One-way flights from Des Moines to Los Angeles
Search for one-way flight options from Des Moines to Los Angeles. Find affordable one-way fares based on user searches. Data last updated October 27, 2025.

Fri 12/57:58 pmDSM - LAX

1 stop24h 40mFrontier

Deal found 10/26

$61

Mon 11/172:32 pmDSM - LAX

1 stop11h 53mFrontier

Deal found 10/25

$71

Sun 11/162:17 pmDSM - LAX

1 stop21h 27mMultiple Airlines

Deal found 10/25

$102

Fri 11/72:32 pmDSM - LAX

1 stop11h 53mFrontier

Deal found 10/26

$103

Tue 12/232:35 pmDSM - LAX

1 stop11h 55mFrontier

Deal found 10/27

$107

Mon 12/228:29 pmDSM - LAX

1 stop13h 13mFrontier

Deal found 10/26

$113

Sun 1/258:30 amDSM - LAX

1 stop14h 38mMultiple Airlines

Deal found 10/27

$114

Sun 1/411:50 amDSM - LAX

1 stop26h 26mMultiple Airlines

Deal found 10/25

$117

Tue 12/302:35 pmDSM - LAX

1 stop19h 07mFrontier

Deal found 10/25

$123

Cheap flight deals from Des Moines to Los Angeles

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$185 (Kiwi.com)
One-way from	$61 (Trip.com)
Popular in	March
Cheapest in	May
Average price	$367
Good round-trip deal	$309 or less
Good one-way deal	$137 or less

Provider with most accurate pricing for Des Moines-Los Angeles flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Los Angeles flights.

Search Deals

From Des Moines to Los Angeles

Search Deals

One-way flight from Des Moines to Los Angeles

Search Deals

Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Price to beat on a round-trip flight from Des Moines to Los Angeles.

Search Deals

Price to beat on a one-way flight from Des Moines to Los Angeles.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Los Angeles that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 1/21

5:16 pm-11:55 pm

1 stop8h 39m

Los Angeles

Sat 1/24

10:55 pm-10:41 am

1 stop9h 46m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 12/10

5:45 am-9:21 am

1 stop5h 36m

Los Angeles

Wed 12/10

12:25 am-10:29 am

1 stop8h 04m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/17

5:45 am-9:50 am

1 stop6h 05m

Los Angeles

Sat 1/31

5:25 am-12:40 pm

1 stop5h 15m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/17

1:35 pm-5:25 pm

1 stop5h 50m

Los Angeles

Fri 1/30

12:30 am-10:55 am

1 stop8h 25m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 12/6

11:01 am-2:59 pm

1 stop5h 58m

Los Angeles

Sat 12/13

10:59 pm-10:38 am

1 stop9h 39m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Sat 1/10

7:50 am-1:30 pm

1 stop7h 40m

Los Angeles

Sat 1/17

1:04 pm-8:34 pm

1 stop5h 30m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 12/10

2:16 pm-9:49 pm

1 stop9h 33m

Los Angeles

Wed 12/17

8:25 am-5:47 pm

1 stop7h 22m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Wed 12/3

5:15 pm-9:01 pm

1 stop5h 46m

Los Angeles

Fri 12/12

12:25 am-10:53 am

1 stop8h 28m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Tue 1/6

12:04 pm-9:02 pm

1 stop10h 58m

Los Angeles

Tue 1/13

7:20 am-4:29 pm

1 stop7h 09m

$295

Des MoinesLos Angeles

DSM - LAX

DSMLAX

Des Moines

Fri 12/5

7:58 pm-6:38 pm

1 stop24h 40m

$61

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 19 results

Compare providers for flights from Des Moines to Los Angeles

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Los Angeles in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars
JustAirTicket	Price Accuracy-	Trust Score*1 star
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Los Angeles flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Des Moines-Los Angeles flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Des Moines-Los Angeles flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Los Angeles flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Los Angeles flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Los Angeles

Have a flexible travel schedule? Discover the best time to fly to Los Angeles from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Los Angeles

Prices

Airlines

How far ahead should I book a flight from Des Moines to Los Angeles?

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Los Angeles. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Des Moines to Los Angeles?

Currently, September is the cheapest month in which you can book a flight from Des Moines to Los Angeles (average of $105). Flying from Des Moines to Los Angeles in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to LAX?

A simple way to save on the total cost of your ticket is to fly from Des Moines to Los Angeles in the morning. If you’re flexible enough to do this you can expect to save up to 54% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Des Moines to Los Angeles?

Travelers seeking maximum savings on their Des Moines to Los Angeles flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Los Angeles

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Des Moines to Los Angeles by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,236 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

7,996 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,997 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,033 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,122 reviews

Southwest

8.0

Very good

4,236 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Des Moines to Los Angeles?
You will need to book a flight from Des Moines to Los Angeles if you want to fly from Des Moines to Los Angeles. At least 6 different airlines have flights from Des Moines (DSM) to Los Angeles (LAX) on a regular basis. There is 1 flight to Los Angeles from the Des Moines airport per day. If you manage to book one that is nonstop, then you can expect the flight time from DSM to LAX to be around 3h 50m.
How popular is this Des Moines to Los Angeles flight route?
This flight path from Des Moines to Los Angeles was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Des Moines to Los Angeles?
There are many flights that can get you from Des Moines to Los Angeles in 5h 36m. Fly via Delta or United Airlines to get the fastest option. The distance between Des Moines and Los Angeles is about 1443 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?
According to our current data, Allegiant Air ($127), Frontier ($149), and Delta ($239) offers the cheapest pricing from Des Moines to Los Angeles. You may be able to fly from Des Moines to Los Angeles for 67% less than the average price by searching for these airlines.
What are the cheapest flights from Des Moines to Los Angeles?
On average you can expect to pay $933 for a flight from Des Moines to Los Angeles. The cheapest flight overall is $137 while the most popular route, (Des Moines - Los Angeles) is currently priced at $158.
Can I find deals for flights from Des Moines to Los Angeles that include hotel bookings?
Yes. In addition to deals on Des Moines to Los Angeles flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Los Angeles?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Los Angeles.
Can I find deals for business class flights from Des Moines to Los Angeles?
Yes. Cheapflights offers flight deals from Des Moines to Los Angeles by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Los Angeles?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Los Angeles (average of $105). Flying from Des Moines to Los Angeles in July is currently the most expensive (average of $235). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Top 6 airlines flying from Des Moines to Los Angeles

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$127	Average$173	FlexibilityNo cancel fee	On-time88%
Frontier	Cheapest$149	Average$234	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$239	Average$359	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$256	Average$389	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$285	Average$388	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$294	Average$417	FlexibilityNo cancel fee	On-time63%

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$61+ Cheap flights from Des Moines to Los Angeles (DSM - LAX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Los Angeles with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Los Angeles are usually found in May or July, booked 80 days in advance, depart on a Monday or Friday and return on a Tuesday

Find flight deals from Des Moines to Los Angeles

Cheapest flights from Des Moines to Los AngelesExplore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

Cheap flight deals from Des Moines to Los Angeles

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Los Angeles that are best for you.

Compare providers for flights from Des Moines to Los Angeles

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Los Angeles in October.

Best time to book a flight from Des Moines to Los Angeles

Have a flexible travel schedule? Discover the best time to fly to Los Angeles from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Los Angeles

How far ahead should I book a flight from Des Moines to Los Angeles?

What is the cheapest month to book a flight from Des Moines to Los Angeles?

What is the cheapest time of day to fly from DSM to LAX?

What is the cheapest day to fly from Des Moines to Los Angeles?

Weekly flight availability from Des Moines to Los Angeles

What’s the top layover airport for flights from Des Moines to Los Angeles?

What’s the fastest layover option from Des Moines to Los Angeles?

What’s the fastest layover option from Des Moines to Los Angeles?

Which airport typically offers the quickest layover for flights from Des Moines to Los Angeles?

Reviews of airlines servicing Los Angeles

Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Des Moines to Los Angeles by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Los Angeles. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Des Moines to Los Angeles?

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What are the cheapest airlines flying from Des Moines to Los Angeles round-trip?

What are the cheapest flights from Des Moines to Los Angeles?

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Alternative routes for Des Moines to Los Angeles

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Top 6 airlines flying from Des Moines to Los Angeles

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Cheapest flights from Des Moines to Los Angeles
Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.