$80+ Cheap flights from Des Moines to Los Angeles (DSM - LAX)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — LAX
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Los Angeles with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Des Moines to Los Angeles Los Angeles are usually found in January or May, booked 80 days in advance, depart on a Wednesday or Saturday and return on a Thursday
Cheap flight deals from Des Moines to Los Angeles
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to Los AngelesExplore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Des Moines to Los Angeles. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:15 pm
DSM
- LAX
1 stop5h 15m
Southwest
Tue 4/148:40 am
LAX
- DSM
1 stop7h 15m
Southwest
Deal found 3/10![Southwest logo]()
$159
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:10 pm
DSM
- LAX
1 stop5h 15m
Southwest
Fri 5/110:40 am
LAX
- DSM
2 stops10h 25m
Southwest
Deal found 3/10![Southwest logo]()
$164
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:55 am
DSM
- LAX
2 stops8h 05m
Southwest
Fri 4/1710:40 am
LAX
- DSM
2 stops10h 25m
Southwest
Deal found 3/10![Southwest logo]()
$169
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:15 pm
DSM
- LAX
2 stops8h 50m
Southwest
Sat 4/115:20 am
LAX
- DSM
1 stop10h 40m
Southwest
Deal found 3/10![Southwest logo]()
$170
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:01 pm
DSM
- LAX
1 stop8h 49m
American Airlines
Fri 4/1711:41 pm
LAX
- DSM
1 stop8h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$179
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:56 pm
DSM
- LAX
Nonstop3h 57m
American Airlines
Sat 5/212:50 pm
LAX
- DSM
Nonstop3h 35m
American Airlines
Deal found 3/11![American Airlines logo]()
$180
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:12 pm
DSM
- LAX
Nonstop4h 08m
American Airlines
Wed 4/812:50 pm
LAX
- DSM
Nonstop3h 35m
American Airlines
Deal found 3/10![American Airlines logo]()
$188
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:56 pm
DSM
- LAX
Nonstop3h 57m
American Airlines
Thu 4/96:10 am
LAX
- DSM
1 stop5h 37m
American Airlines
Deal found 3/10![American Airlines logo]()
$189
Best flights from Des Moines to Los AngelesDiscover carefully curated flight deals from Des Moines to Los Angeles that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Des Moines to Los Angeles that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 pm
DSM
- LAX
1 stop5h 35m
Southwest
Thu 4/98:15 am
LAX
- DSM
1 stop8h 20m
Southwest
Deal found 3/9![Southwest logo]()
$164
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:47 pm
DSM
- LAX
1 stop8h 05m
Delta
Tue 4/146:00 am
LAX
- DSM
1 stop9h 02m
Delta
Deal found 3/12![Delta logo]()
$237
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:17 pm
DSM
- LAX
1 stop6h 33m
United Airlines
Mon 4/2711:59 pm
LAX
- DSM
1 stop8h 45m
United Airlines
Deal found 3/12![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:45 pm
DSM
- LAX
1 stop8h 20m
Southwest
Tue 4/212:05 pm
LAX
- DSM
1 stop5h 10m
Southwest
Deal found 3/11![Southwest logo]()
$199
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:40 am
DSM
- LAX
2 stops7h 30m
Southwest
Sat 5/21:20 pm
LAX
- DSM
1 stop5h 35m
Southwest
Deal found 3/10![Southwest logo]()
$204
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:56 am
DSM
- LAX
1 stop8h 34m
Delta
Mon 5/2510:35 pm
LAX
- DSM
1 stop9h 11m
Delta
Deal found 3/12![Delta logo]()
$288
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/101:45 pm
DSM
- LAX
1 stop8h 20m
Southwest
Thu 5/711:10 am
LAX
- DSM
1 stop5h 25m
Southwest
Deal found 3/8![Southwest logo]()
$249
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:45 pm
DSM
- LAX
1 stop5h 50m
Southwest
Thu 5/711:10 am
LAX
- DSM
1 stop5h 25m
Southwest
Deal found 3/8![Southwest logo]()
$258
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- LAX
2 stops8h 55m
Southwest
Fri 5/110:40 am
LAX
- DSM
2 stops10h 25m
Southwest
Deal found 3/9![Southwest logo]()
$296
Last-minute flights from Des Moines to Los AngelesDiscover last-minute flight deals from Des Moines to Los Angeles. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Los Angeles. Data last updated March 13, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/33:12 pm
DSM
- LAX
Nonstop4h 08m
American Airlines
Wed 4/812:50 pm
LAX
- DSM
Nonstop3h 35m
American Airlines
Deal found 3/10![American Airlines logo]()
$188
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/67:15 pm
DSM
- LAX
1 stop5h 15m
Southwest
Tue 4/148:40 am
LAX
- DSM
1 stop7h 15m
Southwest
Deal found 3/10![Southwest logo]()
$159
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/73:15 pm
DSM
- LAX
2 stops8h 50m
Southwest
Sat 4/115:20 am
LAX
- DSM
1 stop10h 40m
Southwest
Deal found 3/10![Southwest logo]()
$170
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:56 pm
DSM
- LAX
Nonstop3h 57m
American Airlines
Thu 4/96:10 am
LAX
- DSM
1 stop5h 37m
American Airlines
Deal found 3/10![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:55 am
DSM
- LAX
2 stops8h 05m
Southwest
Fri 4/1710:40 am
LAX
- DSM
2 stops10h 25m
Southwest
Deal found 3/10![Southwest logo]()
$169
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:01 pm
DSM
- LAX
1 stop8h 49m
American Airlines
Fri 4/1711:41 pm
LAX
- DSM
1 stop8h 45m
American Airlines
Deal found 3/10![American Airlines logo]()
$179
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:10 pm
DSM
- LAX
1 stop5h 15m
Southwest
Fri 5/110:40 am
LAX
- DSM
2 stops10h 25m
Southwest
Deal found 3/10![Southwest logo]()
$164
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:56 pm
DSM
- LAX
Nonstop3h 57m
American Airlines
Sat 5/212:50 pm
LAX
- DSM
Nonstop3h 35m
American Airlines
Deal found 3/11![American Airlines logo]()
$180
One-way flights from Des Moines to Los AngelesSearch for one-way flight options from Des Moines to Los Angeles. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Des Moines to Los Angeles. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:05 pm
DSM
- LAX
1 stop7h 35m
Southwest
Deal found 3/10![Southwest logo]()
$80
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/32:15 pm
DSM
- LAX
1 stop10h 00m
Southwest
Deal found 3/10![Southwest logo]()
$85
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:35 pm
DSM
- LAX
1 stop6h 05m
Southwest
Deal found 3/9![Southwest logo]()
$90
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:40 pm
DSM
- LAX
1 stop12h 10m
Southwest
Deal found 3/9![Southwest logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/410:00 am
DSM
- LAX
1 stop11h 35m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$96
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:23 pm
DSM
- LAX
1 stop5h 31m
American Airlines
Deal found 3/10![American Airlines logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:00 am
DSM
- LAX
1 stop24h 06m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/69:45 pm
DSM
- LAX
1 stop13h 21m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$102
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:20 pm
DSM
- LAX
2 stops8h 55m
Southwest
Deal found 3/10![Southwest logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:11 pm
DSM
- LAX
1 stop16h 47m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$108
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:01 am
DSM
- LAX
1 stop5h 54m
Delta
Deal found 3/9![Delta logo]()
$109
Find flight deals from Des Moines to Los Angeles
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Los Angeles (LAX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $159 (Southwest) |
One-way from | $80 (Southwest) |
Popular in | December |
Cheapest in | January |
Average price | $373 |
Good round-trip deal | $326 or less |
Good one-way deal | $117 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Los Angeles that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Des Moines to Los Angeles that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Tue 4/7
6:30 pm-10:05 pm
1 stop5h 35m
Los Angeles Los Angeles
Thu 4/9
8:15 am-6:35 pm
1 stop8h 20m
$164
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Fri 4/17
1:45 pm-8:05 pm
1 stop8h 20m
Los Angeles Los Angeles
Tue 4/21
2:05 pm-9:15 pm
1 stop5h 10m
$199
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Sat 4/25
6:40 am-12:10 pm
2 stops7h 30m
Los Angeles Los Angeles
Sat 5/2
1:20 pm-8:55 pm
1 stop5h 35m
$204
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Wed 4/8
5:47 pm-11:52 pm
1 stop8h 05m
Los Angeles Los Angeles
Tue 4/14
6:00 am-5:02 pm
1 stop9h 02m
$237
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Fri 4/10
1:45 pm-8:05 pm
1 stop8h 20m
Los Angeles Los Angeles
Thu 5/7
11:10 am-6:35 pm
1 stop5h 25m
$249
Quickest round-trip
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Thu 4/9
1:45 pm-5:35 pm
1 stop5h 50m
Los Angeles Los Angeles
Thu 5/7
11:10 am-6:35 pm
1 stop5h 25m
$258
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Thu 4/23
5:17 pm-9:50 pm
1 stop6h 33m
Los Angeles Los Angeles
Mon 4/27
11:59 pm-10:44 am
1 stop8h 45m
$279
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Thu 5/21
10:56 am-5:30 pm
1 stop8h 34m
Los Angeles Los Angeles
Mon 5/25
10:35 pm-9:46 am
1 stop9h 11m
$288
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Fri 4/24
4:20 pm-11:15 pm
2 stops8h 55m
Los Angeles Los Angeles
Fri 5/1
10:40 am-11:05 pm
2 stops10h 25m
$296
Cheapest one-way
Des MoinesLos Angeles
DSM - LAX
DSMLAX
Des Moines
Sun 4/12
11:00 am-9:06 am
1 stop24h 06m
$101
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Des Moines to Los Angeles
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Los Angeles in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Des Moines-Los Angeles flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Los Angeles flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Los Angeles flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Des Moines-Los Angeles flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Los Angeles flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Des Moines to Los Angeles
Have a flexible travel schedule? Discover the best time to fly to Los Angeles from Des Moines with our price prediction graph.
DSM-LAX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Los Angeles
Prices
Airlines
More
How far ahead should I book a flight from Des Moines to Los Angeles?
Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Los Angeles. Price data was last updated on March 6, 2026.
Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Des Moines to Los Angeles. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Des Moines to Los Angeles?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Los Angeles (average of $105). Flying from Des Moines to Los Angeles in December is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DSM to LAX?
Find hourly flight availability from Des Moines to Los Angeles. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 13, 2026.
A simple way to save on the total cost of your ticket is to fly from Des Moines to Los Angeles in the morning. If you’re flexible enough to do this you can expect to save up to 52% on your trip compared to booking a flight in the afternoon.
What’s the top layover airport for flights from Des Moines to Los Angeles?
Share of 1-stop round-trip flights from Des Moines to Los Angeles chosen by Cheapflights users in the past 12 months, using the same layover each way.
St. Louis (STL) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Los Angeles on Cheapflights.
What’s the cheapest layover airport for flights from Des Moines to Los Angeles?
Average round-trip fare for 1-stop flights from Des Moines to Los Angeles, chosen by Cheapflights users in the past 12 months, with the same layover each way.
St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $284.
What’s the fastest layover option from Des Moines to Los Angeles?
Shortest average travel time for 1-stop one-way flights from Des Moines to Los Angeles, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 5h 34m.
Which airport typically offers the quickest layover for flights from Des Moines to Los Angeles?
Average layover duration for 1-stop one-way flights from Des Moines to Los Angeles, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 0h 54m.
Reviews of airlines servicing Los Angeles
Get insights into the airlines that provide service to Los Angeles. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Los Angeles. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Des Moines to Los Angeles by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentWalter,Aug 2025
OAK - SAN
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Los Angeles. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Des Moines and Los Angeles flights
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Top 6 airlines flying from Des Moines to Los Angeles
Discover the top 6 airlines that operate flights from Des Moines to Los Angeles. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$67 | Average$144 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$149 | Average$234 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$239 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$246 | Average$364 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$275 | Average$374 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$294 | Average$381 | FlexibilityNo cancel fee | On-time63% |