HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indianapolis

$53+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
8月 5 — 8月 121
週二 8/5
週二 8/12
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Indianapolis with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated 7月 31, 2025.

Round-trip from

$159
(Cheapflightsfares)

One-way from

$53
(FlightHub)

Popular in

March

Cheapest in

June

Average price

$416

Good one-way deal

$38 or less
From South Carolina to Indianapolis
Search Deals
One-way flight from South Carolina to Indianapolis
Search Deals
Highest demand for flights based on searches. 32% potential increase in price ($182 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals
Price to beat on a one-way flight from South Carolina to Indianapolis.
Search Deals

Find flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 7月 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週五 9/56:00 amCLT - IND
1 stop11h 19mSpirit Airlines
週日 9/75:00 amIND - CLT
1 stop9h 29mSpirit Airlines
Deal found 7/30$159
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週六 12/1311:40 amCHS - IND
1 stop12h 52mSpirit Airlines
週一 12/151:28 pmIND - CHS
1 stop27h 17mSpirit Airlines
Deal found 7/30$169
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週六 9/65:50 pmCLT - IND
Nonstop1h 38mAmerican Airlines
週一 9/86:11 amIND - CLT
Nonstop1h 40mAmerican Airlines
Deal found 7/30$169
This FlightHub deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週一 9/2212:23 pmMYR - IND
1 stop7h 49mSpirit Airlines
週四 9/255:30 amIND - MYR
1 stop10h 55mSpirit Airlines
Deal found 7/31$172
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週一 9/1512:02 pmSAV - IND
1 stop8h 10mSpirit Airlines
週四 9/185:00 amIND - SAV
1 stop6h 07mSpirit Airlines
Deal found 7/29$173
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週六 9/66:33 pmCLT - IND
1 stop5h 35mDelta
週二 9/96:30 amIND - CLT
1 stop5h 30mDelta
Deal found 7/30$177
This CheapOair deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週日 8/177:03 pmCLT - IND
1 stop23h 18mMultiple Airlines
週二 8/193:05 pmIND - CLT
1 stop7h 53mMultiple Airlines
Deal found 7/29$179
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週四 9/257:17 pmCAE - IND
1 stop14h 01mMultiple Airlines
週日 9/285:30 amIND - CAE
1 stop10h 41mMultiple Airlines
Deal found 7/29$185
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週四 9/257:17 pmCAE - IND
1 stop14h 01mSpirit Airlines
週日 9/2811:10 amIND - CAE
1 stop7h 11mSpirit Airlines
Deal found 7/29$187
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週三 9/244:06 pmCAE - IND
1 stop7h 33mAmerican Airlines
週六 9/276:00 amIND - CAE
1 stop4h 06mAmerican Airlines
Deal found 7/29$191
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週六 8/97:03 pmCLT - IND
1 stop22h 50mFrontier
週一 8/117:16 pmIND - CLT
1 stop16h 26mFrontier
Deal found 7/30$195
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
週三 9/247:48 pmCAE - IND
1 stop4h 11mUnited Airlines
週六 9/277:15 amIND - CAE
2 stops7h 03mUnited Airlines
Deal found 7/29$196

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 7月 31, 2025.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

South Carolina

Fly to

Indianapolis

Route

Depart

Return

Price

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

週五 9/5

6:00 am-5:19 pm

1 stop11h 19m

Indianapolis

週日 9/7

5:00 am-2:29 pm

1 stop9h 29m

$159

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

週六 9/6

5:50 pm-7:28 pm

Nonstop1h 38m

Indianapolis

週一 9/8

6:11 am-7:51 am

Nonstop1h 40m

$169

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

週六 12/13

11:40 am-12:32 am

1 stop12h 52m

Indianapolis

週一 12/15

1:28 pm-4:45 pm

1 stop27h 17m

$169

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

週一 9/22

12:23 pm-8:12 pm

1 stop7h 49m

Indianapolis

週四 9/25

5:30 am-4:25 pm

1 stop10h 55m

$172

SavannahIndianapolis

SAV - IND

SAVIND

Savannah/Hilton Head

週一 9/15

12:02 pm-8:12 pm

1 stop8h 10m

Indianapolis

週四 9/18

5:00 am-11:07 am

1 stop6h 07m

$173

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

週六 9/6

6:33 pm-12:08 am

1 stop5h 35m

Indianapolis

週二 9/9

6:30 am-12:00 pm

1 stop5h 30m

$177

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

週日 8/17

7:03 pm-6:21 pm

1 stop23h 18m

Indianapolis

週二 8/19

3:05 pm-10:58 pm

1 stop7h 53m

$179

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

週四 9/25

7:17 pm-9:18 am

1 stop14h 01m

Indianapolis

週日 9/28

5:30 am-4:11 pm

1 stop10h 41m

$185

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

週四 9/25

7:17 pm-9:18 am

1 stop14h 01m

Indianapolis

週日 9/28

11:10 am-6:21 pm

1 stop7h 11m

$187

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

週三 9/24

4:06 pm-11:39 pm

1 stop7h 33m

Indianapolis

週六 9/27

6:00 am-10:06 am

1 stop4h 06m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 7月 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated 7月 31, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from South Carolina to Indianapolis by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Allegiant Air
7.2
Good
702 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $53. However, be on the lookout for offers from Frontier and American Airlines, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Charlotte Douglas - Indianapolis, Greenville - Indianapolis or Charleston - Indianapolis as they are the most popular.

  • What are the cheapest flights from South Carolina to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $49. While the most popular route (Charlotte Douglas - Indianapolis) can be booked for $99 on average our data indicates $120 when flying from South Carolina to Indianapolis.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Indianapolis?

Book flights to Indianapolis if you plan to visit one of these locations
Greenwood
Bloomington
Noblesville
Muncie
Fishers
Terre Haute
Anderson
Kokomo
Franklin
Plainfield
Carmel
Crawfordsville
Shelbyville
Speedway

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to O'Hare Intl flights
Newark to O'Hare Intl flights
LaGuardia to O'Hare Intl flights
John F Kennedy Intl to O'Hare Intl flights
Los Angeles to O'Hare Intl flights
Seattle to O'Hare Intl flights
Reagan-National to O'Hare Intl flights
San Francisco to O'Hare Intl flights
Philadelphia to O'Hare Intl flights
Dulles Intl to O'Hare Intl flights
Boston to O'Hare Intl flights
Baltimore to O'Hare Intl flights
John F Kennedy Intl to Midway flights
Newark to Midway flights
Ontario to O'Hare Intl flights
LaGuardia to Midway flights
Dallas/Fort Worth to Midway flights
Santa Ana to O'Hare Intl flights
Sky Harbor Intl to O'Hare Intl flights
Atlanta to Midway flights
Dulles Intl to Midway flights
Denver to O'Hare Intl flights
Raleigh to O'Hare Intl flights
Burbank to O'Hare Intl flights
Austin to O'Hare Intl flights
Atlanta to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Baltimore to Midway flights
Hobby to O'Hare Intl flights
Love Field to O'Hare Intl flights
Miami to O'Hare Intl flights
San Diego to O'Hare Intl flights
George Bush Intcntl to O'Hare Intl flights
Charlotte to O'Hare Intl flights
Minneapolis to O'Hare Intl flights
San Jose to O'Hare Intl flights
Portland to O'Hare Intl flights
Nashville to O'Hare Intl flights
Philadelphia to Midway flights
Hobby to Midway flights
Orlando to O'Hare Intl flights
Minneapolis to Midway flights
Oakland to O'Hare Intl flights
Los Angeles to Midway flights
San Francisco to Midway flights
Tampa to O'Hare Intl flights
Boston to Indianapolis flights
LaGuardia to Indianapolis flights
Boston to Midway flights
Dallas/Fort Worth to Cincinnati flights

Top 6 airlines flying from South Carolina to Indianapolis

Discover the top 6 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated 7月 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$45Average$133FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$149Average$251FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$190Average$456FlexibilityNo cancel feeOn-time69%
DeltaCheapest$212Average$365FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$387FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$406FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.