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$49+ Cheap flights from South Carolina to Indianapolis (IND)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — IND
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from South Carolina to Indianapolis

Keep the following information in mind while searching for South Carolina to Indianapolis flight deals. Data was last updated June 12, 2025.

Round-trip from

$88
(Booking.com)

One-way from

$49
(Kiwi.com)

Popular in

March

Cheapest in

June

Average price

$234

Good round-trip deal

$126 or less

Good one-way deal

$45 or less
From South Carolina to Indianapolis
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One-way flight from South Carolina to Indianapolis
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Highest demand for flights based on searches. 33% potential increase in price ($187 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($35 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a round-trip flight from South Carolina to Indianapolis.
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Price to beat on a one-way flight from South Carolina to Indianapolis.
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Find flight deals from South Carolina to Indianapolis

Cheapest flights from South Carolina to Indianapolis
Explore the most affordable flight options available from South Carolina to Indianapolis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/129:51 pmMYR - IND
Nonstop1h 45mAllegiant Air
Sat 7/197:26 pmIND - MYR
Nonstop1h 40mAllegiant Air
Deal found 6/11$88
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/43:05 pmCHS - IND
Nonstop1h 50mAllegiant Air
Fri 7/1112:31 pmIND - CHS
Nonstop1h 44mAllegiant Air
Deal found 6/10$90
This Booking.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/128:34 amMYR - IND
1 stop6h 50mMultiple Airlines
Sat 7/197:26 pmIND - MYR
Nonstop1h 40mMultiple Airlines
Deal found 6/11$121
This Mytrip deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/47:03 amCHS - IND
1 stop11h 49mMultiple Airlines
Mon 7/2112:31 pmIND - CHS
Nonstop1h 44mMultiple Airlines
Deal found 6/11$135
This Priceline deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/264:03 pmCLT - IND
Nonstop1h 39mSpirit Airlines
Sun 6/296:37 pmIND - CLT
Nonstop1h 56mSpirit Airlines
Deal found 6/12$170
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/810:41 amCLT - IND
Nonstop1h 38mAmerican Airlines
Mon 8/118:08 amIND - CLT
Nonstop1h 42mAmerican Airlines
Deal found 6/12$179
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/121:02 pmCHS - IND
1 stop23h 20mSpirit Airlines
Sun 9/145:45 pmIND - CHS
1 stop24h 36mSpirit Airlines
Deal found 6/10$181
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/152:16 pmCAE - IND
1 stop19h 30mMultiple Airlines
Sun 8/1710:00 amIND - CAE
1 stop27h 21mMultiple Airlines
Deal found 6/10$186
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:05 amCLT - IND
1 stop5h 13mDelta
Tue 9/26:30 amIND - CLT
1 stop5h 30mDelta
Deal found 6/10$188
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/102:59 pmCAE - IND
1 stop7h 49mSpirit Airlines
Fri 7/116:30 amIND - CAE
1 stop9h 12mSpirit Airlines
Deal found 6/10$188
This Cheapflightsfares deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/276:10 amMYR - IND
1 stop5h 42mSpirit Airlines
Mon 6/3012:57 pmIND - MYR
1 stop6h 25mSpirit Airlines
Deal found 6/10$191
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/65:40 pmCAE - IND
1 stop5h 45mAmerican Airlines
Sat 8/95:40 amIND - CAE
2 stops7h 04mAmerican Airlines
Deal found 6/11$196

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Indianapolis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from South Carolina to Indianapolis that are best for you.

Fly from

South Carolina

Fly to

Indianapolis

Route

Depart

Return

Price

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 7/12

9:51 pm-11:36 pm

Nonstop1h 45m

Indianapolis

Sat 7/19

7:26 pm-9:06 pm

Nonstop1h 40m

$88

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Fri 7/4

3:05 pm-4:55 pm

Nonstop1h 50m

Indianapolis

Fri 7/11

12:31 pm-2:15 pm

Nonstop1h 44m

$90

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Sat 7/12

8:34 am-3:24 pm

1 stop6h 50m

Indianapolis

Sat 7/19

7:26 pm-9:06 pm

Nonstop1h 40m

$121

CharlestonIndianapolis

CHS - IND

CHSIND

Charleston

Fri 7/4

7:03 am-6:52 pm

1 stop11h 49m

Indianapolis

Mon 7/21

12:31 pm-2:15 pm

Nonstop1h 44m

$135

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 6/26

4:03 pm-5:42 pm

Nonstop1h 39m

Indianapolis

Sun 6/29

6:37 pm-8:33 pm

Nonstop1h 56m

$170

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Fri 8/8

10:41 am-12:19 pm

Nonstop1h 38m

Indianapolis

Mon 8/11

8:08 am-9:50 am

Nonstop1h 42m

$179

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Fri 8/15

2:16 pm-9:46 am

1 stop19h 30m

Indianapolis

Sun 8/17

10:00 am-1:21 pm

1 stop27h 21m

$186

CharlotteIndianapolis

CLT - IND

CLTIND

Charlotte Douglas

Thu 8/28

6:05 am-11:18 am

1 stop5h 13m

Indianapolis

Tue 9/2

6:30 am-12:00 pm

1 stop5h 30m

$188

ColumbiaIndianapolis

CAE - IND

CAEIND

Columbia Metropolitan

Thu 7/10

2:59 pm-10:48 pm

1 stop7h 49m

Indianapolis

Fri 7/11

6:30 am-3:42 pm

1 stop9h 12m

$188

Myrtle BeachIndianapolis

MYR - IND

MYRIND

Myrtle Beach Intl

Fri 6/27

6:10 am-11:52 am

1 stop5h 42m

Indianapolis

Mon 6/30

12:57 pm-7:22 pm

1 stop6h 25m

$191

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Indianapolis

Have a flexible travel schedule? Discover the best time to fly to Indianapolis from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Indianapolis

What is the cheapest month to book a flight from South Carolina to Indianapolis?

Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to IND?

Find hourly flight availability from South Carolina to Indianapolis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Indianapolis as you normally would.

Rainfall in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indianapolis ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indianapolis when rainfall is around 2.3 in.

Temperature in Indianapolis by month

Plan your trip to Indianapolis by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indianapolis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indianapolis

Get insights into the airlines that provide service to Indianapolis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indianapolis. Reviews last updated June 12, 2025.
Read through reviews of airlines operating flights from South Carolina to Indianapolis, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,946 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Allegiant Air
7.3
Good
725 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Indianapolis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Indianapolis from South Carolina?

    Indianapolis (IND) is the airport you will fly into if you book a flight from South Carolina to Indianapolis. It is only a 8.3 mi journey from Indianapolis (IND) to Indianapolis’s city center.

  • How popular is this South Carolina to Indianapolis flight route?

    The South Carolina to Indianapolis flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from South Carolina to Indianapolis one-way?

    The cheapest airline one-way is Allegiant Air, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from Spirit Airlines and Delta, as they are both options that can get you from South Carolina to Indianapolis for a low price.

  • What are the most popular routes from South Carolina to Indianapolis?

    When deciding which route to take from South Carolina to Indianapolis consider Columbia Metropolitan - Indianapolis, Charlotte Douglas - Indianapolis or Savannah/Hilton Head - Indianapolis as they are the most popular.

  • What are the cheapest flights from South Carolina to Indianapolis?

    Looking at all options, your cheapest flight can be booked for $45. While the most popular route (Columbia Metropolitan - Indianapolis) can be booked for $186 on average our data indicates $106 when flying from South Carolina to Indianapolis.

  • Can I find deals for flights from South Carolina to Indianapolis that include hotel bookings?

    Yes. In addition to deals on South Carolina to Indianapolis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Indianapolis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Indianapolis.

  • Can I find deals for business class flights from South Carolina to Indianapolis?

    Yes. Cheapflights offers flight deals from South Carolina to Indianapolis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Indianapolis?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to Indianapolis (average of $297). Flying from South Carolina to Indianapolis in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Greenwood
Bloomington
Terre Haute
Noblesville
Muncie
Fishers
Anderson
Kokomo
Franklin
Plainfield
Crawfordsville
Carmel
Shelbyville
Speedway

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Alternative routes for South Carolina to Indianapolis

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Indianapolis

Discover the top 6 airlines that operate flights from South Carolina to Indianapolis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$92Average$140FlexibilityNo cancel feeOn-time88%
Spirit AirlinesCheapest$146Average$251FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$190Average$428FlexibilityNo cancel feeOn-time69%
DeltaCheapest$220Average$355FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$377FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$286Average$402FlexibilityNo cancel feeOn-time63%

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