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$105+ Cheap flights from Des Moines (DSM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
May 4 — May 111
Sun 5/4
Sun 5/11
1 adult, Economy
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Cheap flight deals from Des Moines to Indiana

Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated April 29, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$189
(American Airlines)

One-way from

$105
(Southwest)

Popular in

June

Cheapest in

January

Average price

$316
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
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From Des Moines to Indiana
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One-way flight from Des Moines to Indiana
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Highest demand for flights based on searches. 15% potential increase in price ($62 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Des Moines to Indiana

Cheapest flights from Des Moines to Indiana
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/175:00 amDSM - ORD
Nonstop1h 27mAmerican Airlines
Sat 8/210:25 pmORD - DSM
Nonstop1h 19mAmerican Airlines
Deal found 4/29$189
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/176:45 pmDSM - ORD
Nonstop1h 36mUnited Airlines
Wed 5/219:00 amORD - DSM
Nonstop1h 30mUnited Airlines
Deal found 4/29$194
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/85:30 pmDSM - MDW
1 stop2h 55mSouthwest
Tue 8/125:40 pmMDW - DSM
1 stop4h 40mSouthwest
Deal found 4/29$209
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/221:07 pmDSM - ORD
1 stop3h 38mDelta
Sun 5/256:24 amORD - DSM
1 stop4h 56mDelta
Deal found 4/29$209
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/254:14 pmDSM - SDF
1 stop19h 58mMultiple Airlines
Tue 6/312:58 pmSDF - DSM
1 stop25h 35mMultiple Airlines
Deal found 4/27$210
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/28:35 amDSM - ORD
1 stop22h 52mMultiple Airlines
Tue 6/39:02 pmORD - DSM
1 stop17h 28mMultiple Airlines
Deal found 4/29$212
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:30 amDSM - ORD
1 stop7h 40mSouthwest
Mon 8/252:55 pmORD - DSM
2 stops7h 55mSouthwest
Deal found 4/28$214
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/238:20 pmDSM - CVG
1 stop27h 35mFrontier
Fri 5/306:05 amCVG - DSM
1 stop14h 30mFrontier
Deal found 4/29$222
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/206:30 amDSM - SDF
1 stop6h 25mDelta
Sat 5/246:19 amSDF - DSM
1 stop6h 01mDelta
Deal found 4/28$229
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/298:30 amDSM - IND
1 stop14h 09mAllegiant Air
Mon 6/27:30 amIND - DSM
1 stop7h 23mAllegiant Air
Deal found 4/28$230
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/205:27 pmDSM - SDF
1 stop5h 58mAmerican Airlines
Sat 5/247:24 amSDF - DSM
2 stops9h 02mAmerican Airlines
Deal found 4/28$234
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/95:52 pmDSM - IND
1 stop5h 07mDelta
Sat 7/124:43 pmIND - DSM
1 stop5h 24mDelta
Deal found 4/28$240

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.

Fly from

Des Moines

Fly to

Indiana

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 7/17

5:00 am-6:27 am

Nonstop1h 27m

Chicago O'Hare Intl

Sat 8/2

10:25 pm-11:44 pm

Nonstop1h 19m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 5/17

6:45 pm-8:21 pm

Nonstop1h 36m

Chicago O'Hare Intl

Wed 5/21

9:00 am-10:30 am

Nonstop1h 30m

$194

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 5/22

1:07 pm-4:45 pm

1 stop3h 38m

Chicago O'Hare Intl

Sun 5/25

6:24 am-11:20 am

1 stop4h 56m

$209

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Sun 5/25

4:14 pm-1:12 pm

1 stop19h 58m

Louisville Intl

Tue 6/3

12:58 pm-1:33 pm

1 stop25h 35m

$210

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Mon 6/2

8:35 am-7:27 am

1 stop22h 52m

Chicago O'Hare Intl

Tue 6/3

9:02 pm-2:30 pm

1 stop17h 28m

$212

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Tue 8/19

6:30 am-2:10 pm

1 stop7h 40m

Chicago O'Hare Intl

Mon 8/25

2:55 pm-10:50 pm

2 stops7h 55m

$214

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Mon 6/9

6:30 pm-9:25 pm

1 stop2h 55m

Chicago Midway

Wed 6/11

7:05 am-11:00 am

1 stop3h 55m

$219

Des MoinesCincinnati

DSM - CVG

DSMCVG

Des Moines

Fri 5/23

8:20 pm-12:55 am

1 stop27h 35m

Cincinnati Cinci./N. Kentucky

Fri 5/30

6:05 am-7:35 pm

1 stop14h 30m

$222

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Tue 5/20

6:30 am-1:55 pm

1 stop6h 25m

Louisville Intl

Sat 5/24

6:19 am-11:20 am

1 stop6h 01m

$229

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Thu 5/29

8:30 am-11:39 pm

1 stop14h 09m

Indianapolis

Mon 6/2

7:30 am-1:53 pm

1 stop7h 23m

$230

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 52 results
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Best time to book a flight from Des Moines to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indiana

What is the cheapest month to book a flight from Des Moines to Indiana?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $297). Flying from Des Moines to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IN?

Find hourly flight availability from Des Moines to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Indiana as you normally would.

Rainfall in Indiana by month

Plan your trip to Indiana by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Indiana ranges from 2.3 - 5.1 inches per month. May is typically the wettest month, when rainfall can reach 5.1 in. February is typically the driest time to visit Indiana when rainfall is around 2.3 in.

Temperature in Indiana by month

Plan your trip to Indiana by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Indiana, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 28.4 F).

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated April 29, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from Des Moines to Indiana. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,929 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Allegiant Air
7.3
Good
734 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Food

7.1

Comfort

8.0

Boarding

8.2

Entertainment

7.6

Overall

8.0

Crew

8.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Indiana?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Indiana from Des Moines.

  • What are the cheapest airlines to fly from Des Moines to Indiana one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $105. Allegiant Air flights start at $110 while deals on Delta start at $128 one-way.

  • What are the most popular routes from Des Moines to Indiana?

    While some choose either Des Moines - Chicago Midway or Des Moines - Indianapolis, Des Moines - Chicago O'Hare Intl is the most popular route from Des Moines to Indiana.

  • Can I find deals for flights from Des Moines to Indiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indiana.

  • Can I find deals for business class flights from Des Moines to Indiana?

    Yes. Cheapflights offers flight deals from Des Moines to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $297). Flying from Des Moines to Indiana in March is currently the most expensive (average of $361). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indiana

Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$307FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$226Average$441FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$244Average$432FlexibilityNo cancel feeOn-time71%

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