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$65+ Cheap flights from Des Moines (DSM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Des Moines to Indiana

Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated September 11, 2025.

Round-trip from

$181
(Priceline)

One-way from

$65
(Southwest)

Popular in

November

Cheapest in

July

Average price

$326
From Des Moines to Indiana
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One-way flight from Des Moines to Indiana
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Highest demand for flights based on searches. 7% potential increase in price ($27 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Indiana

Cheapest flights from Des Moines to Indiana
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Priceline deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:32 pmDSM - CVG
1 stop10h 07mFrontier
Sun 11/25:05 amCVG - DSM
1 stop8h 42mFrontier
Deal found 9/10$181
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2911:15 amDSM - IND
1 stop5h 20mAmerican Airlines
Tue 11/47:00 pmIND - DSM
1 stop5h 30mAmerican Airlines
Deal found 9/10$189
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/35:00 amDSM - ORD
Nonstop1h 28mAmerican Airlines
Sun 10/56:45 amORD - DSM
Nonstop1h 24mAmerican Airlines
Deal found 9/10$189
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/213:48 pmDSM - SDF
1 stop5h 37mAmerican Airlines
Wed 10/227:33 amSDF - DSM
1 stop5h 46mAmerican Airlines
Deal found 9/10$189
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/308:25 amDSM - MDW
2 stops9h 00mSouthwest
Wed 10/16:00 amMDW - DSM
1 stop8h 40mSouthwest
Deal found 9/10$190
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2511:58 amDSM - ORD
Nonstop1h 33mAmerican Airlines
Sat 11/18:35 pmORD - DSM
Nonstop1h 30mAmerican Airlines
Deal found 9/10$190
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2110:15 amDSM - SDF
1 stop12h 20mSouthwest
Wed 10/223:50 pmSDF - DSM
2 stops7h 00mSouthwest
Deal found 9/10$190
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/247:03 amDSM - ORD
Nonstop1h 31mAmerican Airlines
Thu 10/96:55 amORD - DSM
Nonstop1h 27mAmerican Airlines
Deal found 9/9$194
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:00 amDSM - ORD
1 stop9h 45mSouthwest
Tue 9/307:00 amORD - DSM
1 stop7h 40mSouthwest
Deal found 9/10$195
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:45 pmDSM - MDW
1 stop5h 20mSouthwest
Thu 10/167:40 amMDW - DSM
1 stop3h 20mSouthwest
Deal found 9/11$196
This Priceline deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/252:25 pmDSM - CVG
1 stop10h 15mFrontier
Sun 9/286:18 amCVG - DSM
1 stop8h 22mFrontier
Deal found 9/11$196
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:36 pmDSM - ORD
Nonstop1h 34mUnited Airlines
Sun 9/284:00 pmORD - DSM
Nonstop1h 24mUnited Airlines
Deal found 9/10$199

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.

Fly from

Des Moines

Fly to

Indiana

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 10/10

6:36 pm-8:10 pm

Nonstop1h 34m

Chicago O'Hare Intl

Sun 10/12

9:05 am-10:32 am

Nonstop1h 27m

$189

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Tue 10/21

3:48 pm-10:25 pm

1 stop5h 37m

Louisville Intl

Wed 10/22

7:33 am-12:19 pm

1 stop5h 46m

$189

Des MoinesLouisville

DSM - SDF

DSMSDF

Des Moines

Tue 10/21

10:15 am-11:35 pm

1 stop12h 20m

Louisville Intl

Wed 10/22

3:50 pm-9:50 pm

2 stops7h 00m

$190

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Mon 10/27

1:48 pm-3:21 pm

Nonstop1h 33m

Chicago O'Hare Intl

Mon 11/3

7:02 am-8:34 am

Nonstop1h 32m

$190

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 10/14

4:45 pm-10:05 pm

1 stop5h 20m

Chicago Midway

Thu 10/16

7:40 am-11:00 am

1 stop3h 20m

$196

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 9/30

8:25 am-12:40 pm

1 stop4h 15m

Chicago Midway

Wed 10/1

6:25 am-11:25 am

1 stop5h 00m

$200

Des MoinesIndianapolis

DSM - IND

DSMIND

Des Moines

Sat 12/6

5:25 am-12:15 pm

1 stop5h 50m

Indianapolis

Tue 12/9

1:15 pm-9:35 pm

2 stops9h 20m

$203

Des MoinesCincinnati

DSM - CVG

DSMCVG

Des Moines

Fri 10/24

2:37 pm-1:49 am

1 stop10h 12m

Cincinnati Cinci./N. Kentucky

Fri 10/31

6:05 am-1:47 pm

1 stop8h 42m

$204

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 10/4

2:49 pm-9:30 pm

1 stop6h 41m

Chicago O'Hare Intl

Sat 10/11

10:30 am-4:52 pm

1 stop6h 22m

$209

Des MoinesCincinnati

DSM - CVG

DSMCVG

Des Moines

Sat 10/18

5:47 am-12:02 pm

1 stop5h 15m

Cincinnati Cinci./N. Kentucky

Sat 10/18

6:04 pm-10:30 pm

1 stop5h 26m

$217

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indiana

What is the cheapest month to book a flight from Des Moines to Indiana?

Currently, August is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $286). Flying from Des Moines to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IN?

Find hourly flight availability from Des Moines to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Indiana as you normally would.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Indiana?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Indiana from Des Moines.

  • How long is the flight from Des Moines to Indiana?

    A quick flight from Des Moines to Indiana can take about 1h 34m. United Airlines provides one of the quickest options available for as low as $189. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to Indiana one-way?

    To fly one-way, consider booking your trip with Southwest, which is currently one of the cheapest options available, starting at $65. Frontier flights start at $82 while deals on Delta start at $89 one-way.

  • What are the most popular routes from Des Moines to Indiana?

    While some choose either Des Moines - Chicago Midway or Des Moines - Cincinnati Cinci./N. Kentucky, Des Moines - Chicago O'Hare Intl is the most popular route from Des Moines to Indiana.

  • Can I find deals for flights from Des Moines to Indiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indiana.

  • Can I find deals for business class flights from Des Moines to Indiana?

    Yes. Cheapflights offers flight deals from Des Moines to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indiana?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $286). Flying from Des Moines to Indiana in March is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indiana

Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$314FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$345FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$449FlexibilityNo cancel feeOn-time69%

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