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$60+ Cheap flights from Des Moines (DSM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Nov 12 — Nov 191
Wed 11/12
Wed 11/19
1 adult, Economy
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Find flight deals from Des Moines to Indiana

Cheapest flights from Des Moines to Indiana
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2025.

This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:56 pmDSM - ORD
Nonstop1h 52mAmerican Airlines
Fri 11/2811:02 amORD - DSM
Nonstop1h 34mAmerican Airlines
Deal found 10/12$189
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:41 amDSM - ORD
Nonstop1h 42mAmerican Airlines
Thu 12/410:09 amORD - DSM
Nonstop1h 33mAmerican Airlines
Deal found 10/13$190
This Frontier deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/302:32 pmDSM - ORD
1 stop10h 11mFrontier
Sun 11/25:00 amORD - DSM
1 stop7h 47mFrontier
Deal found 10/12$191
This Frontier deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/62:41 pmDSM - CVG
1 stop9h 58mFrontier
Sun 11/96:05 amCVG - DSM
1 stop8h 42mFrontier
Deal found 10/13$191
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:26 amDSM - ORD
Nonstop1h 31mUnited Airlines
Sun 11/212:59 pmORD - DSM
Nonstop1h 20mUnited Airlines
Deal found 10/12$194
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/253:25 pmDSM - ORD
Nonstop1h 33mUnited Airlines
Wed 10/2912:59 pmORD - DSM
Nonstop1h 20mUnited Airlines
Deal found 10/11$199
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/268:47 pmDSM - ORD
1 stop26h 57mMultiple Airlines
Wed 10/294:03 pmORD - DSM
2 stops43h 12mMultiple Airlines
Deal found 10/11$201
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/172:32 pmDSM - ORD
1 stop9h 43mMultiple Airlines
Thu 11/208:59 amORD - DSM
2 stops23h 45mMultiple Airlines
Deal found 10/11$202
This Kiwi.com deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:53 pmDSM - ORD
1 stop28h 20mMultiple Airlines
Thu 12/47:39 pmORD - DSM
1 stop23h 29mMultiple Airlines
Deal found 10/10$206
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/256:17 amDSM - MDW
1 stop6h 17mDelta
Tue 12/29:59 amMDW - DSM
1 stop7h 04mDelta
Deal found 10/11$209
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:00 amDSM - ORD
1 stop5h 52mDelta
Fri 11/286:00 amORD - DSM
1 stop4h 20mDelta
Deal found 10/12$209
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/271:43 pmDSM - ORD
1 stop10h 01mMultiple Airlines
Wed 10/297:43 pmORD - DSM
1 stop14h 08mMultiple Airlines
Deal found 10/11$213

Cheap flight deals from Des Moines to Indiana

Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated October 13, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$189
(United Airlines)

One-way from

$60
(Frontier)

Popular in

October

Cheapest in

September

Average price

$438
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indiana
Search Deals
One-way flight from Des Moines to Indiana
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.

Fly from

Des Moines

Fly to

Indiana

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Wed 12/3

3:17 pm-4:48 pm

Nonstop1h 31m

Chicago O'Hare Intl

Sat 12/6

9:17 am-10:53 am

Nonstop1h 36m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 11/21

1:06 pm-2:48 pm

Nonstop1h 42m

Chicago O'Hare Intl

Sun 11/23

10:16 pm-11:44 pm

Nonstop1h 28m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 11/27

8:02 am-9:35 am

Nonstop1h 33m

Chicago O'Hare Intl

Sat 11/29

12:20 am-1:42 am

Nonstop1h 22m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sun 12/21

8:00 am-9:38 am

Nonstop1h 38m

Chicago O'Hare Intl

Tue 1/27

1:09 pm-2:33 pm

Nonstop1h 24m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 12/4

3:17 pm-4:48 pm

Nonstop1h 31m

Chicago O'Hare Intl

Sun 12/7

8:10 pm-9:37 pm

Nonstop1h 27m

$189

Des MoinesCincinnati

DSM - CVG

DSMCVG

Des Moines

Thu 11/6

2:41 pm-1:39 am

1 stop9h 58m

Cincinnati Cinci./N. Kentucky

Sun 11/9

6:05 am-1:47 pm

1 stop8h 42m

$191

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Sun 11/9

5:45 am-9:55 am

1 stop4h 10m

Chicago Midway

Sun 11/16

6:45 am-11:00 am

1 stop4h 15m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 3/3

6:20 am-12:35 pm

1 stop6h 15m

Chicago Midway

Wed 3/4

1:00 pm-4:56 pm

1 stop3h 56m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Sat 11/1

3:50 pm-7:05 pm

1 stop3h 15m

Chicago Midway

Sun 11/2

5:45 am-10:00 am

1 stop4h 15m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Tue 12/9

6:17 am-12:34 pm

1 stop6h 17m

Chicago Midway

Thu 12/11

9:34 am-4:16 pm

1 stop6h 42m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/11

Showing 1-10 of 60 results
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Best time to book a flight from Des Moines to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indiana

What is the cheapest month to book a flight from Des Moines to Indiana?

Currently, March is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $179). Flying from Des Moines to Indiana in May is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IN?

Find hourly flight availability from Des Moines to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 13, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 65% on flights from Des Moines to Indiana by exploring options for tickets in the evening.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated October 13, 2025.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,974 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,045 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Indiana?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Indiana from Des Moines.

  • How long is the flight from Des Moines to Indiana?

    A quick flight from Des Moines to Indiana can take about 1h 31m. United Airlines provides one of the quickest options available for as low as $189. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to Indiana one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $60. Delta flights start at $105 while deals on American Airlines start at $133 one-way.

  • What are the most popular routes from Des Moines to Indiana?

    While some choose either Des Moines - Chicago Midway or Des Moines - Cincinnati Cinci./N. Kentucky, Des Moines - Chicago O'Hare Intl is the most popular route from Des Moines to Indiana.

  • Can I find deals for flights from Des Moines to Indiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indiana.

  • Can I find deals for business class flights from Des Moines to Indiana?

    Yes. Cheapflights offers flight deals from Des Moines to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $179). Flying from Des Moines to Indiana in May is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Des Moines to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Des Moines to Indiana

Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$312FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$337FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$461FlexibilityNo cancel feeOn-time69%

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