HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Indiana

$82+ Cheap flights from Des Moines (DSM) to Indiana

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Indiana with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Indiana

Cheapest flights from Des Moines to Indiana
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:40 amDSM - ORD
Nonstop1h 40mAmerican Airlines
Sun 1/411:30 amORD - DSM
Nonstop1h 24mAmerican Airlines
Deal found 12/10$189
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:45 amDSM - ORD
Nonstop1h 44mAmerican Airlines
Thu 1/110:00 pmORD - DSM
Nonstop1h 30mAmerican Airlines
Deal found 12/9$204
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:57 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Mon 12/2911:30 amORD - DSM
Nonstop1h 24mAmerican Airlines
Deal found 12/10$219
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:46 pmDSM - ORD
Nonstop1h 39mUnited Airlines
Mon 1/198:20 pmORD - DSM
Nonstop1h 30mUnited Airlines
Deal found 12/9$234
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:01 pmDSM - ORD
Nonstop1h 52mAmerican Airlines
Sun 1/119:40 amORD - DSM
Nonstop1h 32mAmerican Airlines
Deal found 12/10$235
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/176:50 pmDSM - ORD
Nonstop1h 35mUnited Airlines
Wed 12/246:05 pmORD - DSM
Nonstop1h 24mUnited Airlines
Deal found 12/10$249
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:59 amDSM - MDW
1 stop4h 07mDelta
Tue 1/69:50 amMDW - DSM
1 stop5h 51mDelta
Deal found 12/10$254
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:01 amDSM - ORD
1 stop5h 56mDelta
Sat 1/176:15 amORD - DSM
1 stop4h 04mDelta
Deal found 12/10$254
This Southwest deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/174:15 pmDSM - MDW
2 stops6h 20mSouthwest
Sun 1/186:10 amMDW - DSM
1 stop5h 15mSouthwest
Deal found 12/10$259
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:25 pmDSM - ORD
Nonstop1h 39mAmerican Airlines
Thu 1/159:40 amORD - DSM
Nonstop1h 32mAmerican Airlines
Deal found 12/10$263
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:00 amDSM - ORD
Nonstop1h 38mUnited Airlines
Sun 12/218:10 pmORD - DSM
Nonstop1h 30mUnited Airlines
Deal found 12/10$279
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1212:15 pmDSM - ORD
Nonstop1h 51mAmerican Airlines
Fri 1/26:40 amORD - DSM
Nonstop1h 35mAmerican Airlines
Deal found 12/11$289

Find flight deals from Des Moines to Indiana

Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$189
(Southwest)

One-way from

$82
(Super.com)

Popular in

November

Cheapest in

September

Average price

$308
Provider with most accurate pricing for Des Moines-Indianapolis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Indianapolis flights.
Search Deals
From Des Moines to Indiana
Search Deals
One-way flight from Des Moines to Indiana
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($29 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.

Fly from

Des Moines

Fly to

Indiana

Route

Depart

Return

Price

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Thu 1/1

6:46 pm-8:25 pm

Nonstop1h 39m

Chicago O'Hare Intl

Sun 1/4

9:02 am-10:49 am

Nonstop1h 47m

$189

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 1/30

3:35 pm-5:10 pm

Nonstop1h 35m

Chicago O'Hare Intl

Mon 2/2

8:20 pm-9:50 pm

Nonstop1h 30m

$189

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Sun 1/25

6:24 am-12:46 pm

1 stop6h 22m

Chicago Midway

Sun 2/1

9:53 am-3:41 pm

1 stop5h 48m

$209

Des MoinesChicago

DSM - MDW

DSMMDW

Des Moines

Fri 1/30

6:10 am-9:30 am

1 stop3h 20m

Chicago Midway

Mon 2/2

2:10 pm-7:20 pm

1 stop5h 10m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sun 1/25

4:21 pm-9:43 pm

1 stop5h 22m

Chicago O'Hare Intl

Sun 2/1

6:15 am-10:19 am

1 stop4h 04m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 1/16

4:21 pm-9:43 pm

1 stop5h 22m

Chicago O'Hare Intl

Sun 1/18

6:50 am-11:24 am

1 stop4h 34m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 1/16

4:21 pm-9:43 pm

1 stop5h 22m

Chicago O'Hare Intl

Tue 1/20

1:58 pm-8:54 pm

1 stop6h 56m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Sat 1/24

6:54 am-12:15 pm

1 stop5h 21m

Chicago O'Hare Intl

Sat 1/31

6:15 am-10:19 am

1 stop4h 04m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 1/23

10:21 am-4:38 pm

1 stop6h 17m

Chicago O'Hare Intl

Fri 1/30

10:35 am-5:08 pm

1 stop6h 33m

$209

Des MoinesChicago

DSM - ORD

DSMORD

Des Moines

Fri 3/6

4:21 pm-9:41 pm

1 stop5h 20m

Chicago O'Hare Intl

Sat 3/7

6:15 am-10:17 am

1 stop4h 02m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Des Moines to Indiana

Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Indiana

What is the cheapest month to book a flight from Des Moines to Indiana?

Currently, March is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $179). Flying from Des Moines to Indiana in May is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to IN?

Find hourly flight availability from Des Moines to Indiana. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 65% on flights from Des Moines to Indiana by exploring options for tickets in the evening.

Reviews of airlines servicing Indiana

Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,008 reviews

Overall

7.9

Boarding

8.1

Comfort

7.9

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Des Moines to Indiana?

    Located just 3.6 mi from the city center, Des Moines (DSM) is the airport most travelers will use when flying to Indiana from Des Moines.

  • How long is the flight from Des Moines to Indiana?

    A quick flight from Des Moines to Indiana can take about 1h 39m. United Airlines provides one of the quickest options available for as low as $189. Airlines will cover a distance of 298 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Des Moines to Indiana one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $98. Delta flights start at $123 while deals on United Airlines start at $125 one-way.

  • What are the most popular routes from Des Moines to Indiana?

    While some choose either Des Moines - Chicago Midway or Des Moines - Indianapolis, Des Moines - Chicago O'Hare Intl is the most popular route from Des Moines to Indiana.

  • Can I find deals for flights from Des Moines to Indiana that include hotel bookings?

    Yes. In addition to deals on Des Moines to Indiana flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Indiana?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Indiana.

  • Can I find deals for business class flights from Des Moines to Indiana?

    Yes. Cheapflights offers flight deals from Des Moines to Indiana by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Indiana?

    Currently, March is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $179). Flying from Des Moines to Indiana in May is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Indiana

See prices for flight routes from nearby airports that may be better suited for you.
Omaha to Las Vegas flights
Des Moines to Sky Harbor Intl flights
Omaha to Sky Harbor Intl flights
Omaha to Denver flights
Omaha to Orlando flights
Cedar Rapids to Sky Harbor Intl flights
Des Moines to Orlando flights
Cedar Rapids to Tampa flights
Cedar Rapids to Orlando flights
Des Moines to Denver flights
Cedar Rapids to Denver flights
Omaha to LaGuardia flights
Des Moines to Las Vegas flights
Des Moines to LaGuardia flights
Omaha to Miami flights
Des Moines to Hobby flights
Des Moines to John F Kennedy Intl flights
Moline to Tampa flights
Omaha to Atlanta flights
Des Moines to Tampa flights
Omaha to Dallas/Fort Worth flights
Omaha to O'Hare Intl flights
Des Moines to Miami flights
Omaha to Los Angeles flights
Cedar Rapids to Las Vegas flights
Omaha to John F Kennedy Intl flights
Omaha to Newark flights
Des Moines to George Bush Intcntl flights
Omaha to Tampa flights
Cedar Rapids to Dallas/Fort Worth flights
Cedar Rapids to Seattle flights
Omaha to Hobby flights
Omaha to Honolulu flights
Cedar Rapids to John F Kennedy Intl flights
Moline to Orlando flights
Des Moines to Dallas/Fort Worth flights
Des Moines to Los Angeles flights
Cedar Rapids to Miami flights
Des Moines to Fort Lauderdale flights
Moline to Sky Harbor Intl flights
Des Moines to Sarasota flights
Cedar Rapids to Fort Myers flights
Omaha to San Francisco flights
Cedar Rapids to Phoenix-Mesa Gateway flights
Cedar Rapids to Newark flights
Omaha to George Bush Intcntl flights
Cedar Rapids to LaGuardia flights
Des Moines to Fort Myers flights
Des Moines to Charlotte flights
Omaha to Fort Lauderdale flights

Top 3 airlines flying from Des Moines to Indiana

Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$308FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$315FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$210Average$375FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.