$85+ Cheap flights from Des Moines (DSM) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Jul 11 — Jul 181
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IndianaExplore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 11, 2026.
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:55 pm
DSM
- ORD
Nonstop1h 38m
United Airlines
Wed 9/3012:50 pm
ORD
- DSM
Nonstop1h 25m
United Airlines
Deal found 6/10![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:40 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 9/3010:30 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/10![Southwest logo]()
$210
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:15 am
DSM
- ORD
1 stop6h 18m
Delta
Tue 10/271:35 pm
ORD
- DSM
1 stop7h 17m
Delta
Deal found 6/10![Delta logo]()
$229
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Sat 8/2910:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/8![Southwest logo]()
$232
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:00 am
DSM
- ORD
Nonstop1h 36m
United Airlines
Sat 8/299:00 am
ORD
- DSM
Nonstop1h 26m
United Airlines
Deal found 6/8![United Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:50 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Tue 9/152:15 pm
MDW
- DSM
1 stop6h 45m
Southwest
Deal found 6/10![Southwest logo]()
$242
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DSM
- MDW
1 stop6h 39m
Delta
Sat 8/89:59 am
MDW
- DSM
1 stop4h 05m
Delta
Deal found 6/8![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am
DSM
- IND
1 stop5h 20m
Southwest
Sat 12/122:25 pm
IND
- DSM
1 stop6h 15m
Southwest
Deal found 6/9![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:56 pm
DSM
- ORD
1 stop3h 51m
Delta
Sat 8/296:00 am
ORD
- DSM
1 stop4h 18m
Delta
Deal found 6/8![Delta logo]()
$251
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am
DSM
- SDF
1 stop4h 05m
Southwest
Sat 9/192:55 pm
SDF
- DSM
1 stop6h 50m
Southwest
Deal found 6/10![Southwest logo]()
$251
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1410:15 am
DSM
- ORD
1 stop6h 18m
Delta
Thu 10/296:00 am
ORD
- DSM
1 stop4h 20m
Delta
Deal found 6/10![Delta logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- IND
1 stop21h 59m
Allegiant Air
Thu 7/98:00 am
IND
- DSM
1 stop16h 07m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$254
Best flights from Des Moines to IndianaDiscover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
Discover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 11, 2026.
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/223:11 pm
DSM
- ORD
Nonstop1h 43m
United Airlines
Sat 10/249:00 am
ORD
- DSM
Nonstop1h 31m
United Airlines
Deal found 6/8![United Airlines logo]()
$255
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am
DSM
- SDF
1 stop4h 05m
Southwest
Sat 9/196:45 am
SDF
- DSM
2 stops8h 25m
Southwest
Deal found 6/10![Southwest logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Sun 7/511:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$261
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
DSM
- CVG
1 stop6h 28m
Delta
Sat 9/196:05 am
CVG
- DSM
1 stop5h 12m
Delta
Deal found 6/10![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:40 pm
DSM
- CVG
1 stop16h 23m
Multiple Airlines
Tue 7/149:30 pm
CVG
- DSM
2 stops37h 37m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:30 am
DSM
- MDW
Nonstop1h 15m
Southwest
Mon 8/242:05 pm
MDW
- DSM
1 stop7h 10m
Southwest
Deal found 6/8![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am
DSM
- ORD
Nonstop1h 41m
United Airlines
Wed 10/281:00 pm
ORD
- DSM
Nonstop1h 11m
United Airlines
Deal found 6/10![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:15 pm
DSM
- SDF
1 stop5h 36m
Delta
Sun 10/256:00 am
SDF
- DSM
1 stop5h 18m
Delta
Deal found 6/9![Delta logo]()
$287
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:03 pm
DSM
- AZO
1 stop3h 46m
American Airlines
Sun 7/55:45 am
AZO
- DSM
2 stops8h 11m
American Airlines
Deal found 6/8![American Airlines logo]()
$588
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/297:20 am
DSM
- CVG
1 stop8h 00m
Southwest
Wed 9/23:30 pm
CVG
- DSM
2 stops7h 25m
Southwest
Deal found 6/9![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:08 pm
DSM
- CVG
1 stop29h 23m
Allegiant Air
Thu 7/3012:57 pm
CVG
- DSM
2 stops27h 05m
Allegiant Air
Deal found 6/8![Allegiant Air logo]()
$307
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:00 am
DSM
- MDW
1 stop6h 34m
Delta
Tue 9/299:49 am
MDW
- DSM
1 stop4h 12m
Delta
Deal found 6/10![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:00 am
DSM
- ORD
Nonstop1h 40m
United Airlines
Thu 7/309:25 pm
ORD
- DSM
Nonstop1h 31m
United Airlines
Deal found 6/10![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:00 am
DSM
- ORD
1 stop4h 42m
Delta
Wed 8/191:59 pm
ORD
- DSM
1 stop6h 40m
Delta
Deal found 6/8![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:40 am
DSM
- IND
1 stop5h 30m
Southwest
Mon 8/313:05 pm
IND
- DSM
1 stop7h 10m
Southwest
Deal found 6/10![Southwest logo]()
$295
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:00 am
DSM
- ORD
Nonstop1h 36m
United Airlines
Thu 10/297:45 pm
ORD
- DSM
Nonstop1h 32m
United Airlines
Deal found 6/10![United Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:44 am
DSM
- RFD
1 stop10h 28m
Allegiant Air
Sun 10/410:08 am
RFD
- DSM
1 stop10h 45m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$339
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:45 pm
DSM
- SDF
1 stop3h 40m
Southwest
Tue 7/78:45 am
SDF
- DSM
1 stop3h 45m
Southwest
Deal found 6/9![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:20 am
DSM
- ORD
1 stop4h 08m
Delta
Mon 10/261:35 pm
ORD
- DSM
1 stop7h 17m
Delta
Deal found 6/10![Delta logo]()
$312
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/151:10 pm
DSM
- SDF
1 stop4h 56m
United Airlines
Tue 8/185:15 am
SDF
- DSM
1 stop6h 11m
United Airlines
Deal found 6/8![United Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:00 am
DSM
- RFD
2 stops24h 37m
Multiple Airlines
Fri 7/248:39 am
RFD
- DSM
1 stop13h 36m
Multiple Airlines
Deal found 6/6![Multiple Airlines logo]()
$443
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:30 am
DSM
- RFD
1 stop11h 53m
Allegiant Air
Sun 7/1211:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$369
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:00 pm
DSM
- SDF
1 stop6h 32m
Delta
Fri 7/37:05 am
SDF
- DSM
1 stop4h 40m
Delta
Deal found 6/6![Delta logo]()
$312
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am
DSM
- IND
2 stops8h 10m
Southwest
Sun 9/133:10 pm
IND
- DSM
1 stop7h 20m
Southwest
Deal found 6/7![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/273:26 pm
DSM
- ORD
Nonstop1h 39m
United Airlines
Thu 7/309:25 pm
ORD
- DSM
Nonstop1h 31m
United Airlines
Deal found 6/10![United Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/711:30 am
DSM
- DAY
1 stop5h 20m
Delta
Tue 7/143:56 pm
DAY
- DSM
1 stop7h 33m
Delta
Deal found 6/9![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:10 am
DSM
- IND
2 stops6h 05m
Southwest
Mon 7/136:10 am
IND
- DSM
1 stop7h 40m
Southwest
Deal found 6/10![Southwest logo]()
$322
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
DSM
- DAY
1 stop4h 04m
United Airlines
Mon 7/276:15 pm
DAY
- DSM
1 stop5h 41m
United Airlines
Deal found 6/6![United Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/151:49 pm
DSM
- RFD
1 stop22h 35m
Allegiant Air
Fri 7/248:39 am
RFD
- DSM
1 stop13h 36m
Allegiant Air
Deal found 6/6![Allegiant Air logo]()
$408
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:25 am
DSM
- IND
1 stop5h 20m
Southwest
Thu 7/94:05 pm
IND
- DSM
2 stops8h 30m
Southwest
Deal found 6/9![Southwest logo]()
$322
Last-minute flights from Des Moines to IndianaDiscover last-minute flight deals from Des Moines to Indiana. Data last updated June 11, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indiana. Data last updated June 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Sun 7/511:27 am
RFD
- DSM
1 stop28h 23m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$261
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:34 pm
DSM
- AZO
1 stop5h 22m
Delta
Sun 7/55:25 am
AZO
- DSM
1 stop5h 19m
Delta
Deal found 6/10![Delta logo]()
$278
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:08 am
DSM
- IND
1 stop4h 26m
Delta
Sat 7/45:51 pm
IND
- DSM
1 stop3h 50m
Delta
Deal found 6/7![Delta logo]()
$287
This Booking.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/32:16 pm
DSM
- CVG
1 stop27h 54m
Frontier
Tue 7/78:36 pm
CVG
- DSM
1 stop17h 58m
Frontier
Deal found 6/7![Frontier logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- IND
1 stop21h 59m
Allegiant Air
Thu 7/98:00 am
IND
- DSM
1 stop16h 07m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$254
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:25 am
DSM
- IND
1 stop5h 20m
Southwest
Tue 8/251:55 pm
IND
- DSM
1 stop8h 05m
Southwest
Deal found 6/9![Southwest logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- IND
1 stop21h 59m
Allegiant Air
Mon 7/131:14 pm
IND
- DSM
1 stop10h 16m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:14 pm
DSM
- CVG
1 stop28h 32m
Multiple Airlines
Tue 7/143:43 pm
CVG
- DSM
2 stops43h 24m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:20 am
DSM
- MDW
Nonstop1h 20m
Southwest
Wed 7/159:20 pm
MDW
- DSM
Nonstop1h 30m
Southwest
Deal found 6/8![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/82:45 pm
DSM
- MDW
1 stop3h 33m
Delta
Wed 7/159:54 am
MDW
- DSM
1 stop4h 11m
Delta
Deal found 6/8![Delta logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:08 pm
DSM
- CVG
1 stop29h 23m
Multiple Airlines
Thu 7/3012:18 pm
CVG
- DSM
2 stops11h 49m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:40 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Tue 7/2810:10 am
MDW
- DSM
Nonstop1h 20m
Southwest
Deal found 6/10![Southwest logo]()
$299
One-way flights from Des Moines to IndianaSearch for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
Search for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated June 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Deal found 6/9![Allegiant Air logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:59 am
DSM
- RFD
1 stop21h 30m
Allegiant Air
Deal found 6/10![Allegiant Air logo]()
$101
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:10 am
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 6/8![Southwest logo]()
$105
This Expedia deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/22:16 pm
DSM
- ORD
1 stop6h 37m
Frontier
Deal found 6/10![Frontier logo]()
$105
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
DSM
- MDW
1 stop6h 39m
Delta
Deal found 6/8![Delta logo]()
$115
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:20 am
DSM
- ORD
1 stop6h 19m
Delta
Deal found 6/9![Delta logo]()
$115
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:19 pm
DSM
- ORD
1 stop6h 33m
Frontier
Deal found 6/7![Frontier logo]()
$116
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:50 pm
DSM
- MDW
Nonstop1h 20m
Southwest
Deal found 6/9![Southwest logo]()
$128
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:24 pm
DSM
- ORD
Nonstop1h 39m
United Airlines
Deal found 6/9![United Airlines logo]()
$128
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:16 pm
DSM
- ORD
1 stop6h 37m
Frontier
Deal found 6/6![Frontier logo]()
$129
This Super.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/292:26 pm
DSM
- ORD
1 stop6h 17m
Frontier
Deal found 6/8![Frontier logo]()
$133
This Frontier deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:19 pm
DSM
- ORD
1 stop6h 33m
Frontier
Deal found 6/9![Frontier logo]()
$134
Find flight deals from Des Moines to Indiana
Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated June 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (United Airlines) |
One-way from | $85 (Kiwi.com) |
Popular in | March |
Cheapest in | September |
Average price | $346 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Thu 10/22
3:11 pm-4:54 pm
Nonstop1h 43m
Chicago O'Hare Intl
Sat 10/24
9:00 am-10:31 am
Nonstop1h 31m
$255
Des MoinesLouisville
DSM - SDF
DSMSDF
Des Moines
Wed 9/16
6:10 am-11:15 am
1 stop4h 05m
Louisville Intl
Sat 9/19
6:45 am-2:10 pm
2 stops8h 25m
$256
Des MoinesChicago
DSM - RFD
DSMRFD
Des Moines
Wed 7/1
10:59 am-8:29 am
1 stop21h 30m
Chicago Greater Rockford
Sun 7/5
11:27 am-3:50 pm
1 stop28h 23m
$261
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Sat 8/22
5:30 am-6:45 am
Nonstop1h 15m
Chicago Midway
Mon 8/24
2:05 pm-9:15 pm
1 stop7h 10m
$265
Des MoinesCincinnati
DSM - CVG
DSMCVG
Des Moines
Wed 9/16
6:00 am-1:28 pm
1 stop6h 28m
Cincinnati Cinci./N. Kentucky
Sat 9/19
6:05 am-10:17 am
1 stop5h 12m
$273
Quickest round-trip
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Wed 10/14
6:00 am-7:41 am
Nonstop1h 41m
Chicago O'Hare Intl
Wed 10/28
1:00 pm-2:11 pm
Nonstop1h 11m
$279
Des MoinesCincinnati
DSM - CVG
DSMCVG
Des Moines
Sat 8/29
7:20 am-4:20 pm
1 stop8h 00m
Cincinnati Cinci./N. Kentucky
Wed 9/2
3:30 pm-9:55 pm
2 stops7h 25m
$279
Des MoinesLouisville
DSM - SDF
DSMSDF
Des Moines
Wed 10/21
2:15 pm-8:51 pm
1 stop5h 36m
Louisville Intl
Sun 10/25
6:00 am-10:18 am
1 stop5h 18m
$287
Des MoinesChicago
DSM - MDW
DSMMDW
Des Moines
Sun 9/27
6:00 am-12:34 pm
1 stop6h 34m
Chicago Midway
Tue 9/29
9:49 am-2:01 pm
1 stop4h 12m
$289
Des MoinesChicago
DSM - ORD
DSMORD
Des Moines
Sun 8/9
6:00 am-10:42 am
1 stop4h 42m
Chicago O'Hare Intl
Wed 8/19
1:59 pm-8:39 pm
1 stop6h 40m
$289
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
DSM-RFD
DSM-IND
DSM-ORD
DSM-MDW
DSM-SDF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indiana
DSM-USIN
DSM-RFD
DSM-IND
DSM-ORD
DSM-MDW
What is the cheapest month to book a flight from Des Moines to Indiana?
Currently, September is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $158). Flying from Des Moines to Indiana in March is currently the most expensive (average of $344). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indiana?
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated June 11, 2026.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Indiana
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Complete your trip
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Des Moines and Indiana flights
Browse other Des Moines and Indiana flight options. Last updated on June 11, 2026.
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Des Moines to Indiana flights
Consider these flights traveling from Des Moines to Indiana.
Top 3 airlines flying from Des Moines to Indiana
Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$344 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$298 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$257 | Average$363 | FlexibilityNo cancel fee | On-time69% |