$117+ Cheap flights from Des Moines (DSM) to Indiana
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Nov 7 — Nov 141
Round-trip
1 adult, Economy
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Cheapest flights from Des Moines to IndianaExplore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 8, 2026.
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:30 pm -
1 stop6h 15m
Tue 11/102:40 pm -
1 stop7h 10m
Deal found 10/6![Southwest logo]()
$233
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop6h 45m
Tue 10/273:10 pm -
1 stop6h 30m
Deal found 10/5![Southwest logo]()
$264
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:23 am -
1 stop3h 45m
Sat 11/217:56 pm -
1 stop5h 23m
Deal found 10/7![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:23 am -
1 stop6h 31m
Fri 11/205:31 am -
1 stop4h 24m
Deal found 10/5![American Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
2 stops7h 05m
Mon 11/95:30 pm -
1 stop6h 35m
Deal found 10/6![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop4h 32m
Wed 11/412:12 pm -
1 stop5h 43m
Deal found 10/5![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:26 pm -
1 stop3h 46m
Mon 11/95:30 am -
1 stop4h 16m
Deal found 10/6![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:25 pm -
1 stop6h 05m
Sun 11/86:30 am -
1 stop7h 40m
Deal found 10/6![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:15 pm -
1 stop3h 15m
Mon 11/305:50 pm -
1 stop6h 45m
Deal found 10/5![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:29 pm -
1 stop5h 40m
Sun 11/226:39 am -
1 stop4h 05m
Deal found 10/3![Delta logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop5h 28m
Mon 10/264:39 pm -
1 stop6h 16m
Deal found 10/7![United Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:20 am -
2 stops7h 07m
Sun 12/132:07 pm -
1 stop3h 42m
Deal found 10/7![Delta logo]()
$369
Best flights from Des Moines to IndianaDiscover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
Discover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 8, 2026.
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:30 pm -
1 stop6h 15m
Tue 11/102:40 pm -
1 stop7h 10m
Deal found 10/6![Southwest logo]()
$233
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:57 am -
1 stop3h 31m
Tue 11/105:00 pm -
1 stop4h 43m
Deal found 10/6![Delta logo]()
$233
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:24 pm -
1 stop5h 50m
Sun 11/11:40 pm -
1 stop4h 48m
Deal found 10/4![United Airlines logo]()
$397
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:31 pm -
1 stop4h 38m
Mon 10/267:27 pm -
1 stop4h 47m
Deal found 10/7![American Airlines logo]()
$477
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:53 pm -
1 stop4h 47m
Sun 12/137:05 am -
1 stop4h 16m
Deal found 10/7![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops10h 30m
Sat 11/216:40 am -
1 stop5h 45m
Deal found 10/7![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:29 pm -
1 stop5h 40m
Sun 11/226:39 am -
1 stop4h 05m
Deal found 10/3![Delta logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:45 pm -
1 stop4h 02m
Wed 10/287:10 am -
1 stop4h 22m
Deal found 10/5![United Airlines logo]()
$405
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
1 stop6h 05m
Sun 11/152:25 pm -
2 stops9h 40m
Deal found 10/3![Southwest logo]()
$412
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:55 pm -
1 stop3h 45m
Sat 10/247:40 am -
1 stop3h 51m
Deal found 10/4![United Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:15 pm -
1 stop3h 15m
Mon 11/3011:40 am -
2 stops12h 55m
Deal found 10/3![Southwest logo]()
$428
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:35 am -
1 stop7h 35m
Sat 10/243:38 pm -
1 stop6h 55m
Deal found 10/5![Delta logo]()
$477
This United Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:27 am -
1 stop4h 07m
Thu 10/227:00 pm -
1 stop5h 35m
Deal found 10/5![United Airlines logo]()
$483
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:00 am -
1 stop6h 29m
Mon 11/92:06 pm -
2 stops9h 29m
Deal found 10/6![Delta logo]()
$479
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:30 pm -
1 stop6h 45m
Mon 10/265:55 pm -
1 stop6h 20m
Deal found 10/4![Southwest logo]()
$482
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:27 am -
1 stop5h 20m
Fri 10/237:40 pm -
1 stop4h 55m
Deal found 10/4![United Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:40 am -
2 stops15h 50m
Sun 11/86:30 am -
1 stop7h 40m
Deal found 10/7![Southwest logo]()
$485
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:27 am -
2 stops8h 25m
Fri 10/237:17 am -
1 stop3h 54m
Deal found 10/4![Delta logo]()
$533
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops7h 10m
Mon 10/261:50 pm -
2 stops7h 10m
Deal found 10/7![Delta logo]()
$783
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
2 stops9h 20m
Mon 10/263:11 pm -
1 stop6h 29m
Deal found 10/7![Delta logo]()
$884
Last-minute flights from Des Moines to IndianaDiscover last-minute flight deals from Des Moines to Indiana. Data last updated October 8, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indiana. Data last updated October 8, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 am -
1 stop5h 28m
Mon 10/264:39 pm -
1 stop6h 16m
Deal found 10/7![United Airlines logo]()
$343
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop6h 45m
Tue 10/273:10 pm -
1 stop6h 30m
Deal found 10/5![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am -
1 stop4h 32m
Wed 11/412:12 pm -
1 stop5h 43m
Deal found 10/5![Delta logo]()
$315
This American Airlines deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/27:26 pm -
1 stop3h 46m
Mon 11/95:30 am -
1 stop4h 16m
Deal found 10/6![American Airlines logo]()
$319
This Delta deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:57 am -
1 stop3h 31m
Tue 11/105:00 pm -
1 stop4h 43m
Deal found 10/6![Delta logo]()
$233
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:00 am -
2 stops10h 30m
Tue 11/104:50 pm -
1 stop6h 15m
Deal found 10/6![Southwest logo]()
$238
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:25 pm -
1 stop6h 05m
Sun 11/86:30 am -
1 stop7h 40m
Deal found 10/6![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
2 stops7h 05m
Mon 11/95:30 pm -
1 stop6h 35m
Deal found 10/6![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:23 am -
1 stop3h 45m
Sat 11/217:56 pm -
1 stop5h 23m
Deal found 10/7![American Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:23 am -
1 stop6h 31m
Fri 11/205:31 am -
1 stop4h 24m
Deal found 10/5![American Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:29 pm -
1 stop5h 40m
Sun 11/226:39 am -
1 stop4h 05m
Deal found 10/3![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:15 pm -
1 stop3h 15m
Mon 11/305:50 pm -
1 stop6h 45m
Deal found 10/5![Southwest logo]()
$330
One-way flights from Des Moines to IndianaSearch for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
Search for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated October 8, 2026.
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:30 pm -
1 stop6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Southwest logo]()
$117
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops10h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$122
This Trip.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop17h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Frontier logo]()
$149
This KAYAK deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:00 pm -
1 stop10h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Southwest logo]()
$169
This Delta deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2010:55 am -
1 stop5h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Delta logo]()
$179
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:31 pm -
1 stop3h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/3![American Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 10/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:40 pm -
3 stops49h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/6![Multiple Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:35 am -
2 stops7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/4![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:04 pm -
3 stops37h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:10 am -
2 stops8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![Southwest logo]()
$214
This CheapOair deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:25 pm -
1 stop17h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Frontier logo]()
$226
This American Airlines deal was found by Cheapflights users on 10/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/199:26 am -
1 stop6h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/5![American Airlines logo]()
$249
Find flight deals from Des Moines to Indiana
Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated October 8, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Delta) |
One-way from | $117 (Southwest) |
Popular in | May |
Cheapest in | February |
Average price | $389 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.
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Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Tue 12/8
6:00 am-12:20 pm
1 stop5h 20m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Mon 11/16
3:30 pm-10:50 pm
1 stop6h 20m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$117
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Wed 1/20
10:55 am-5:23 pm
1 stop5h 28m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Fri 11/20
7:24 pm-12:39 am
1 stop4h 15m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Wed 10/28
8:00 am-3:00 pm
1 stop6h 00m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
Quickest round-trip
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Sun 10/25
7:31 pm-12:19 am
1 stop3h 48m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Wed 10/28
5:35 am-1:55 pm
2 stops7h 20m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$204
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Fri 10/30
5:10 am-3:05 pm
2 stops8h 55m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$214
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Fri 11/20
5:25 am-3:35 pm
2 stops9h 10m
Indianapolis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$214
Des MoinesIndianapolis
DSM Des Moines - IND Indianapolis
DSMIND
Des Moines
Tue 11/3
3:30 pm-10:45 pm
1 stop6h 15m
Indianapolis
Tue 11/10
2:40 pm-8:50 pm
1 stop7h 10m
$233
Showing 1-10 of 33 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
DSM-IND
DSM-FWA
DSM-SBN
DSM-EVV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indiana
DSM-USIN
DSM-IND
DSM-FWA
DSM-SBN
DSM-EVV
What is the cheapest month to book a flight from Des Moines to Indiana?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $308). Flying from Des Moines to Indiana in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indiana?
Airfare is below average for this route at the moment.
Des Moines to Indiana flights typically cost between $360 and $571 in November.The cheapest round-trip price found within the last 5 days was $233 on Delta (Nov 3-Nov 10).
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated October 8, 2026.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Overall
7.8
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Des Moines to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Indiana by cabin class
Find flights from Des Moines to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Indiana flights
Browse other Des Moines and Indiana flight options. Last updated on October 8, 2026.
Popular flight searches
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Des Moines to Indiana flights
Consider these flights traveling from Des Moines to Indiana.
Top 3 airlines flying from Des Moines to Indiana
Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$272 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$272 | Average$346 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$372 | FlexibilityNo cancel fee | On-time71% |