$100+ Cheap flights from Des Moines (DSM) to Indiana
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — IND
Sep 8 — Sep 151
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Des Moines to Indiana with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Indiana
Cheapest
Best
Last-minute
One-way
Cheapest flights from Des Moines to IndianaExplore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from Des Moines to Indiana. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Priceline deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop7h 32m
Fri 9/113:02 pm -
1 stop5h 31m
Deal found 8/7![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop23h 32m
Wed 9/307:11 am -
1 stop25h 51m
Deal found 8/5![Multiple Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Sun 9/611:00 am -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:55 pm -
Nonstop1h 46m
Sat 9/511:00 pm -
Nonstop1h 35m
Deal found 8/6![American Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:56 pm -
Nonstop1h 48m
Sun 9/610:45 pm -
Nonstop1h 35m
Deal found 8/6![American Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm -
Nonstop1h 20m
Mon 9/78:50 pm -
Nonstop1h 25m
Deal found 8/7![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
Nonstop1h 36m
Mon 9/712:50 pm -
Nonstop1h 26m
Deal found 8/5![United Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm -
1 stop17h 31m
Wed 9/307:11 am -
1 stop25h 51m
Deal found 8/8![Multiple Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:59 am -
1 stop4h 31m
Sun 9/66:00 am -
1 stop4h 20m
Deal found 8/6![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Sat 9/52:05 pm -
1 stop6h 45m
Deal found 8/6![Southwest logo]()
$259
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am -
Nonstop1h 15m
Sat 9/1910:10 am -
Nonstop1h 20m
Deal found 8/4![Southwest logo]()
$261
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:30 am -
Nonstop1h 39m
Mon 8/3110:45 pm -
Nonstop1h 35m
Deal found 8/4![American Airlines logo]()
$261
Best flights from Des Moines to IndianaDiscover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from Des Moines to Indiana that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Sat 9/510:10 am -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:55 pm -
Nonstop1h 38m
Wed 10/710:00 pm -
Nonstop1h 35m
Deal found 8/6![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:23 am -
1 stop5h 56m
Sun 9/65:50 pm -
1 stop5h 47m
Deal found 8/7![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:05 am -
1 stop5h 56m
Tue 9/222:31 pm -
1 stop3h 55m
Deal found 8/5![American Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:59 am -
1 stop10h 07m
Mon 11/212:27 pm -
1 stop7h 32m
Deal found 8/4![Allegiant Air logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
2 stops42h 33m
Fri 9/257:01 pm -
1 stop19h 30m
Deal found 8/5![Multiple Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:10 pm -
1 stop5h 05m
Mon 11/29:35 pm -
Nonstop1h 25m
Deal found 8/4![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:15 am -
Nonstop1h 36m
Sat 12/129:05 am -
Nonstop1h 15m
Deal found 8/7![United Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am -
Nonstop1h 15m
Mon 8/3110:05 am -
Nonstop1h 20m
Deal found 8/7![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:22 am -
1 stop5h 58m
Sun 10/185:30 am -
1 stop5h 12m
Deal found 8/7![Delta logo]()
$288
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:49 pm -
1 stop3h 52m
Mon 9/76:00 am -
1 stop5h 00m
Deal found 8/8![American Airlines logo]()
$288
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:00 am -
2 stops10h 15m
Sun 9/69:00 am -
1 stop6h 16m
Deal found 8/7![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:50 pm -
Nonstop1h 20m
Tue 9/110:30 am -
Nonstop1h 20m
Deal found 8/5![Southwest logo]()
$261
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:01 pm -
1 stop5h 56m
Tue 10/204:32 pm -
1 stop3h 39m
Deal found 8/7![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:10 am -
Nonstop1h 20m
Sat 10/177:25 pm -
Nonstop1h 20m
Deal found 8/4![Southwest logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 am -
1 stop11h 51m
Fri 9/257:01 pm -
1 stop19h 30m
Deal found 8/8![Allegiant Air logo]()
$357
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop4h 31m
Wed 9/2312:26 pm -
1 stop5h 22m
Deal found 8/5![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:00 am -
1 stop3h 42m
Wed 10/217:05 am -
1 stop4h 26m
Deal found 8/7![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:15 am -
2 stops9h 45m
Fri 9/118:50 pm -
Nonstop1h 25m
Deal found 8/7![Southwest logo]()
$264
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop6h 30m
Thu 9/247:00 am -
1 stop4h 17m
Deal found 8/8![Delta logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:28 am -
1 stop5h 41m
Thu 9/109:29 pm -
1 stop23h 12m
Deal found 8/8![Allegiant Air logo]()
$366
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am -
1 stop6h 21m
Sun 9/62:05 pm -
1 stop4h 23m
Deal found 8/6![United Airlines logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/209:28 am -
1 stop5h 41m
Thu 9/109:29 pm -
2 stops22h 04m
Deal found 8/8![Multiple Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:40 am -
Nonstop1h 20m
Wed 9/306:40 am -
1 stop7h 15m
Deal found 8/6![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am -
1 stop7h 07m
Thu 9/246:30 am -
1 stop4h 47m
Deal found 8/5![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
Nonstop1h 36m
Mon 9/712:50 pm -
Nonstop1h 26m
Deal found 8/6![United Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 am -
1 stop11h 51m
Sun 9/209:29 pm -
1 stop23h 12m
Deal found 8/5![Allegiant Air logo]()
$388
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:54 pm -
1 stop4h 05m
Sat 10/317:00 am -
1 stop4h 11m
Deal found 8/8![Delta logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 am -
1 stop11h 51m
Sun 9/209:29 pm -
2 stops22h 04m
Deal found 8/5![Multiple Airlines logo]()
$447
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop5h 30m
Fri 9/115:20 pm -
2 stops5h 55m
Deal found 8/7![Southwest logo]()
$294
Last-minute flights from Des Moines to IndianaDiscover last-minute flight deals from Des Moines to Indiana. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Indiana. Data last updated August 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:49 pm -
Nonstop1h 48m
Sat 9/123:51 pm -
Nonstop1h 36m
Deal found 8/7![American Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Sun 9/611:00 am -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$237
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/57:56 pm -
Nonstop1h 48m
Sun 9/610:45 pm -
Nonstop1h 35m
Deal found 8/8![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:10 pm -
Nonstop1h 20m
Mon 9/78:50 pm -
Nonstop1h 25m
Deal found 8/7![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am -
Nonstop1h 36m
Mon 9/712:50 pm -
Nonstop1h 26m
Deal found 8/5![United Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:59 am -
1 stop4h 31m
Sun 9/66:00 am -
1 stop4h 20m
Deal found 8/6![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Sat 9/52:05 pm -
1 stop6h 45m
Deal found 8/6![Southwest logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm -
1 stop17h 31m
Wed 9/307:11 am -
1 stop25h 51m
Deal found 8/8![Multiple Airlines logo]()
$253
This Priceline deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop7h 32m
Fri 9/113:02 pm -
1 stop5h 31m
Deal found 8/7![Frontier logo]()
$215
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am -
Nonstop1h 15m
Sat 9/1910:10 am -
Nonstop1h 20m
Deal found 8/4![Southwest logo]()
$261
This American Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:05 am -
Nonstop1h 55m
Sat 9/2612:27 pm -
Nonstop1h 32m
Deal found 8/4![American Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/271:58 pm -
1 stop23h 32m
Wed 9/307:11 am -
1 stop25h 51m
Deal found 8/5![Multiple Airlines logo]()
$232
One-way flights from Des Moines to IndianaSearch for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from Des Moines to Indiana. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Expedia deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1711:29 am -
1 stop7h 32m
Deal found 8/6![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
1 stop6h 50m
Deal found 8/8![Multiple Airlines logo]()
$112
This Expedia deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/62:51 pm -
1 stop19h 10m
Deal found 8/6![Frontier logo]()
$117
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:30 am -
Nonstop1h 15m
Deal found 8/6![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:58 pm -
1 stop23h 32m
Deal found 8/7![Multiple Airlines logo]()
$119
This Orbitz deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/302:51 pm -
1 stop6h 44m
Deal found 8/8![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:58 pm -
1 stop17h 31m
Deal found 8/6![Multiple Airlines logo]()
$127
This Trip.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
1 stop18h 41m
Deal found 8/7![Frontier logo]()
$128
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:59 am -
1 stop4h 58m
Deal found 8/7![Delta logo]()
$129
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/54:20 pm -
1 stop5h 27m
Deal found 8/6![Delta logo]()
$129
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:40 am -
Nonstop1h 20m
Deal found 8/7![Southwest logo]()
$131
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:00 am -
Nonstop1h 36m
Deal found 8/7![United Airlines logo]()
$131
Find flight deals from Des Moines to Indiana
Keep the following information in mind while searching for Des Moines to Indiana flight deals. Data was last updated August 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $215 (Priceline) |
One-way from | $100 (Expedia) |
Popular in | May |
Cheapest in | February |
Average price | $410 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Indiana that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Des Moines to Indiana that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Sat 9/5
5:30 am-6:45 am
Nonstop1h 15m
Chicago Midway
Sat 9/5
10:10 am-11:30 am
Nonstop1h 20m
$237
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Fri 10/30
7:10 pm-12:15 am
1 stop5h 05m
Chicago Midway
Mon 11/2
9:35 pm-11:00 pm
Nonstop1h 25m
$259
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Wed 9/30
6:55 pm-8:33 pm
Nonstop1h 38m
Chicago O'Hare Intl
Wed 10/7
10:00 pm-11:35 pm
Nonstop1h 35m
$261
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Sat 8/29
5:30 am-6:45 am
Nonstop1h 15m
Chicago Midway
Mon 8/31
10:05 am-11:25 am
Nonstop1h 20m
$261
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Mon 8/31
3:50 pm-5:10 pm
Nonstop1h 20m
Chicago Midway
Tue 9/1
10:30 am-11:50 am
Nonstop1h 20m
$261
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Thu 10/15
5:10 am-6:30 am
Nonstop1h 20m
Chicago Midway
Sat 10/17
7:25 pm-8:45 pm
Nonstop1h 20m
$261
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Wed 9/9
7:15 am-5:00 pm
2 stops9h 45m
Chicago Midway
Fri 9/11
8:50 pm-10:15 pm
Nonstop1h 25m
$264
Des MoinesChicago
DSM Des Moines - MDW Chicago Midway
DSMMDW
Des Moines
Mon 9/28
5:40 am-7:00 am
Nonstop1h 20m
Chicago Midway
Wed 9/30
6:40 am-1:55 pm
1 stop7h 15m
$271
Des MoinesLouisville
DSM Des Moines - SDF Louisville Intl
DSMSDF
Des Moines
Wed 9/2
10:23 am-5:19 pm
1 stop5h 56m
Louisville Intl
Sun 9/6
5:50 pm-10:37 pm
1 stop5h 47m
$279
Des MoinesChicago
DSM Des Moines - ORD Chicago O'Hare Intl
DSMORD
Des Moines
Fri 12/11
6:15 am-7:51 am
Nonstop1h 36m
Chicago O'Hare Intl
Sat 12/12
9:05 am-10:20 am
Nonstop1h 15m
$281
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Indiana
Have a flexible travel schedule? Discover the best time to fly to Indiana from Des Moines with our price prediction graph.
DSM-MDW
DSM-ORD
DSM-SDF
DSM-IND
DSM-RFD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Indiana
DSM-USIN
DSM-MDW
DSM-ORD
DSM-SDF
DSM-IND
What is the cheapest month to book a flight from Des Moines to Indiana?
Currently, February is the cheapest month in which you can book a flight from Des Moines to Indiana (average of $308). Flying from Des Moines to Indiana in May is currently the most expensive (average of $606). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Indiana?
Airfare is below average for this route at the moment.
Des Moines to Indiana flights typically cost between $366 and $453 in September.The cheapest round-trip price found within the last 5 days was $215 on Frontier (Sep 10-Sep 11).
Reviews of airlines servicing Indiana
Get insights into the airlines that provide service to Indiana. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Indiana. Reviews last updated August 9, 2026.
Read through reviews of airlines operating flights from Des Moines to Indiana, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Indiana. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for Des Moines to Indiana
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Indiana by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Des Moines to Indiana by cabin class
Find flights from Des Moines to Indiana, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Indiana flights
Browse other Des Moines and Indiana flight options. Last updated on August 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Des Moines to Indiana flights
Consider these flights traveling from Des Moines to Indiana.
Top 3 airlines flying from Des Moines to Indiana
Discover the top 3 airlines that operate flights from Des Moines to Indiana. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$254 | Average$311 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$272 | Average$358 | FlexibilityNo cancel fee | On-time69% |