$287+ Cheap flights from Charlotte to Florence, SC (CLT - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — FLO
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Charlotte to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charlotte to Florence
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Cheapest flights from Charlotte to FlorenceExplore the most affordable flight options available from Charlotte to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Charlotte to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:05 pm -
Nonstop1h 04m
Sun 10/112:34 pm -
Nonstop1h 10m
Deal found 9/6![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:55 pm -
Nonstop1h 03m
Wed 9/236:24 am -
Nonstop1h 03m
Deal found 9/4![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:50 pm -
Nonstop1h 06m
Thu 12/175:09 am -
Nonstop1h 12m
Deal found 9/3![American Airlines logo]()
$503
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:15 pm -
Nonstop1h 03m
Sun 9/202:36 pm -
Nonstop1h 04m
Deal found 9/2![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:15 pm -
Nonstop1h 05m
Tue 9/86:22 am -
Nonstop1h 08m
Deal found 9/4![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:07 pm -
Nonstop1h 05m
Tue 9/86:22 am -
Nonstop1h 08m
Deal found 9/4![American Airlines logo]()
$608
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:50 pm -
Nonstop1h 07m
Thu 9/241:43 pm -
Nonstop1h 04m
Deal found 9/5![American Airlines logo]()
$811
Best flights from Charlotte to FlorenceDiscover carefully curated flight deals from Charlotte to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Charlotte to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:05 pm -
Nonstop1h 04m
Sun 10/112:34 pm -
Nonstop1h 10m
Deal found 9/6![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:55 pm -
Nonstop1h 03m
Wed 9/236:24 am -
Nonstop1h 03m
Deal found 9/4![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1010:50 pm -
Nonstop1h 06m
Thu 12/175:09 am -
Nonstop1h 12m
Deal found 9/3![American Airlines logo]()
$503
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:50 pm -
Nonstop1h 07m
Thu 9/241:43 pm -
Nonstop1h 04m
Deal found 9/5![American Airlines logo]()
$811
Last-minute flights from Charlotte to FlorenceDiscover last-minute flight deals from Charlotte to Florence. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Charlotte to Florence. Data last updated September 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:15 pm -
Nonstop1h 05m
Tue 9/86:22 am -
Nonstop1h 08m
Deal found 9/4![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/61:07 pm -
Nonstop1h 05m
Tue 9/86:22 am -
Nonstop1h 08m
Deal found 9/4![American Airlines logo]()
$608
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:15 pm -
Nonstop1h 03m
Sun 9/202:36 pm -
Nonstop1h 04m
Deal found 9/2![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:55 pm -
Nonstop1h 03m
Wed 9/236:24 am -
Nonstop1h 03m
Deal found 9/4![American Airlines logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:50 pm -
Nonstop1h 07m
Thu 9/241:43 pm -
Nonstop1h 04m
Deal found 9/5![American Airlines logo]()
$811
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/101:05 pm -
Nonstop1h 04m
Sun 10/112:34 pm -
Nonstop1h 10m
Deal found 9/6![American Airlines logo]()
$467
One-way flights from Charlotte to FlorenceSearch for one-way flight options from Charlotte to Florence. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Charlotte to Florence. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:15 pm -
Nonstop1h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![American Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:13 pm -
Nonstop1h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/64:43 pm -
Nonstop1h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:55 pm -
Nonstop1h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/510:54 pm -
Nonstop1h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:05 pm -
Nonstop1h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$446
This American Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:05 pm -
Nonstop1h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![American Airlines logo]()
$606
Find flight deals from Charlotte to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Charlotte (CLT) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $467 (American Airlines) |
One-way from | $287 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Charlotte to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Charlotte to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Sat 2/27
4:41 pm-5:49 pm
Nonstop1h 08m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Tue 12/8
9:55 pm-10:59 pm
Nonstop1h 04m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Sat 10/31
4:30 pm-5:34 pm
Nonstop1h 04m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
Quickest round-trip
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Wed 12/2
2:06 pm-3:09 pm
Nonstop1h 03m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Sat 12/5
2:06 pm-3:09 pm
Nonstop1h 03m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Tue 9/29
12:15 pm-1:18 pm
Nonstop1h 03m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Tue 11/3
2:13 pm-3:16 pm
Nonstop1h 03m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Tue 3/2
4:41 pm-5:49 pm
Nonstop1h 08m
Florence
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$381
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Sat 10/10
1:05 pm-2:09 pm
Nonstop1h 04m
Florence
Sun 10/11
2:34 pm-3:44 pm
Nonstop1h 10m
$467
CharlotteFlorence
CLT Charlotte Douglas - FLO Florence
CLTFLO
Charlotte Douglas
Sat 9/19
9:55 pm-10:58 pm
Nonstop1h 03m
Florence
Wed 9/23
6:24 am-7:27 am
Nonstop1h 03m
$479
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Charlotte to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Charlotte to Florence in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Charlotte-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Charlotte-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Charlotte-Florence, South Carolina flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Charlotte-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Charlotte-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Charlotte to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Charlotte with our price prediction graph.
CLT-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charlotte to Florence
Related info for your journey
Find useful and relevant information for your journey from Charlotte to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
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