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Des Moines

$119+ Cheap flights from Charleston to Des Moines (CHS - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — DSM
jul. 5 — jul. 121
sáb. 7/5
sáb. 7/12
1 adult, Economy
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Cheap flight deals from Charleston to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Charleston (CHS) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated junio 30, 2025.

Round-trip from

$237
(American Airlines)

One-way from

$119
(American Airlines)

Popular in

February

Cheapest in

May

Average price

$454
From Charleston to Des Moines
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One-way flight from Charleston to Des Moines
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Highest demand for flights based on searches. 25% potential increase in price ($152 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Charleston to Des Moines

Cheapest flights from Charleston to Des Moines
Explore the most affordable flight options available from Charleston to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 30, 2025.

This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/277:38 pmCHS - DSM
1 stop4h 20mAmerican Airlines
mar. 9/23:48 pmDSM - CHS
1 stop5h 33mAmerican Airlines
Deal found 6/28$237
This Delta deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/275:15 amCHS - DSM
2 stops9h 54mDelta
mar. 9/22:49 pmDSM - CHS
2 stops8h 02mDelta
Deal found 6/28$247
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/246:35 amCHS - DSM
1 stop4h 45mUnited Airlines
lun. 1/53:15 pmDSM - CHS
1 stop4h 49mUnited Airlines
Deal found 6/28$367
This Mytrip deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/2510:53 amCHS - DSM
3 stops31h 23mMultiple Airlines
mar. 7/298:00 amDSM - CHS
2 stops13h 50mMultiple Airlines
Deal found 6/28$430
This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/16:05 amCHS - DSM
2 stops7h 45mSouthwest
lun. 8/46:25 amDSM - CHS
2 stops9h 15mSouthwest
Deal found 6/28$492

Cheapflights Fare Finder

Customize your flight search to find flights from Charleston to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 30, 2025.
Use the filters below to find and compare flights from Charleston to Des Moines that are best for you.

Fly from

Charleston

Fly to

Des Moines

Route

Depart

Return

Price

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/27

7:38 pm-10:58 pm

1 stop4h 20m

Des Moines

mar. 9/2

3:48 pm-10:21 pm

1 stop5h 33m

$237

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 8/27

5:15 am-2:09 pm

2 stops9h 54m

Des Moines

mar. 9/2

2:49 pm-11:51 pm

2 stops8h 02m

$247

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mié. 12/24

6:35 am-10:20 am

1 stop4h 45m

Des Moines

lun. 1/5

3:15 pm-9:04 pm

1 stop4h 49m

$367

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

vie. 7/25

10:53 am-5:16 pm

3 stops31h 23m

Des Moines

mar. 7/29

8:00 am-10:50 pm

2 stops13h 50m

$430

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

vie. 8/1

6:05 am-12:50 pm

2 stops7h 45m

Des Moines

lun. 8/4

6:25 am-4:40 pm

2 stops9h 15m

$492

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

9:19 am-2:29 pm

1 stop6h 10m

$119

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

mar. 10/7

7:20 am-5:13 pm

2 stops10h 53m

$124

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

jue. 8/7

2:28 pm-8:49 am

2 stops19h 21m

$172

CharlestonDes Moines

CHS - DSM

CHSDSM

Charleston

jue. 8/7

6:05 am-10:29 am

1 stop5h 24m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/28

Best time to book a flight from Charleston to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Des Moines

What is the cheapest month to book a flight from Charleston to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to DSM?

Find hourly flight availability from Charleston to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 30, 2025.

When flying from Charleston to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 16% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated junio 30, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Charleston to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,278 reviews

Food

7.0

Entertainment

7.6

Overall

8.0

Boarding

8.2

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,278 reviews
Southwest
8.0
Very good
4,278 reviews

Food

7.0

Entertainment

7.6

Overall

8.0

Boarding

8.2

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,969 reviews
Southwest
8.0
Very good
4,278 reviews

Food

7.0

Entertainment

7.6

Overall

8.0

Boarding

8.2

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,852 reviews
Southwest
8.0
Very good
4,278 reviews

Food

7.0

Entertainment

7.6

Overall

8.0

Boarding

8.2

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,278 reviews

Food

7.0

Entertainment

7.6

Overall

8.0

Boarding

8.2

Crew

8.6

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Charleston to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Charleston to Des Moines round-trip?

    Currently priced at $237, American Airlines will fly you from Charleston to Des Moines and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and United Airlines - these airlines can fly you to your destination from $247 and $367, respectively. American Airlines is 47% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Charleston to Des Moines one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $119. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Charleston to Des Moines for a low price.

  • Can I find deals for flights from Charleston to Des Moines that include hotel bookings?

    Yes. In addition to deals on Charleston to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Des Moines.

  • Can I find deals for business class flights from Charleston to Des Moines?

    Yes. Cheapflights offers flight deals from Charleston to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Charleston to Des Moines (average of $336). Flying from Charleston to Des Moines in June is currently the most expensive (average of $405). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top 2 airlines flying from Charleston to Des Moines

Discover the top 2 airlines that operate flights from Charleston to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$372FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$270Average$536FlexibilityNo cancel feeOn-time71%

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