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Central America

$104+ Cheap flights from Missouri to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Missouri to Central America

Keep the following information in mind while searching for Missouri to Central America flight deals. Data was last updated July 31, 2025.

Round-trip from

$231
(Cheapflightsfares)

One-way from

$104
(Mytrip)

Popular in

December

Cheapest in

August

Average price

$626
From Missouri to Central America
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One-way flight from Missouri to Central America
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Highest demand for flights based on searches. 27% potential increase in price ($220 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Central America

Cheapest flights from Missouri to Central America
Explore the most affordable flight options available from Missouri to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1811:44 amMCI - GUA
1 stop12h 45mSpirit Airlines
Sat 8/3011:15 amGUA - MCI
1 stop10h 38mSpirit Airlines
Deal found 7/31$231
This Mytrip deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:00 amMCI - SJO
1 stop10h 13mMultiple Airlines
Thu 9/47:30 amSJO - MCI
1 stop14h 37mMultiple Airlines
Deal found 7/31$253
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:17 pmSTL - SJO
1 stop7h 44mAmerican Airlines
Thu 11/137:00 amSJO - STL
1 stop15h 32mAmerican Airlines
Deal found 7/29$279
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:00 amSTL - LIR
1 stop7h 00mDelta
Wed 10/11:25 pmLIR - STL
1 stop7h 35mDelta
Deal found 7/31$295
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/17:01 amSTL - LIR
1 stop6h 58mAmerican Airlines
Wed 10/112:49 pmLIR - STL
2 stops22h 08mAmerican Airlines
Deal found 7/29$299
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1811:44 amMCI - GUA
1 stop12h 45mMultiple Airlines
Mon 8/259:41 pmGUA - MCI
2 stops24h 12mMultiple Airlines
Deal found 7/30$314
This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/124:23 pmMCI - SJO
2 stops19h 49mSpirit Airlines
Tue 8/1911:27 amSJO - MCI
1 stop10h 26mSpirit Airlines
Deal found 7/29$315
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1810:35 amSTL - SJO
1 stop25h 39mSpirit Airlines
Wed 10/2212:19 pmSJO - STL
1 stop20h 21mSpirit Airlines
Deal found 7/30$317
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/65:15 amMCI - SAL
2 stops32h 25mSpirit Airlines
Sun 9/211:45 pmSAL - MCI
1 stop19h 43mSpirit Airlines
Deal found 7/30$338
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1811:51 amSTL - SJO
1 stop10h 24mDelta
Tue 11/257:00 amSJO - STL
1 stop11h 02mDelta
Deal found 7/31$340
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:41 amSTL - BZE
1 stop6h 39mAmerican Airlines
Tue 11/41:12 pmBZE - STL
1 stop9h 46mAmerican Airlines
Deal found 7/29$342
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/95:00 amSTL - LIR
1 stop7h 53mUnited Airlines
Fri 8/1511:49 amLIR - STL
1 stop9h 01mUnited Airlines
Deal found 7/30$345

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Missouri

Fly to

Central America

Route

Depart

Return

Price

Kansas CityGuatemala City

MCI - GUA

MCIGUA

Kansas City

Mon 8/18

11:44 am-11:29 pm

1 stop12h 45m

Guatemala City La Aurora

Sat 8/30

11:15 am-10:53 pm

1 stop10h 38m

$231

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Thu 8/28

6:00 am-3:13 pm

1 stop10h 13m

San José Juan Santamaria Intl

Thu 9/4

7:30 am-11:07 pm

1 stop14h 37m

$253

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Fri 10/24

5:20 am-6:16 pm

1 stop13h 56m

San José Juan Santamaria Intl

Sun 11/2

5:00 am-1:53 pm

1 stop8h 53m

$284

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 9/1

6:00 am-12:00 pm

1 stop7h 00m

Liberia

Wed 10/1

1:25 pm-10:00 pm

1 stop7h 35m

$295

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 9/1

7:01 am-12:59 pm

1 stop6h 58m

Liberia

Wed 10/1

12:49 pm-11:57 am

2 stops22h 08m

$299

Kansas CityGuatemala City

MCI - GUA

MCIGUA

Kansas City

Mon 8/18

11:44 am-11:29 pm

1 stop12h 45m

Guatemala City La Aurora

Mon 8/25

9:41 pm-10:53 pm

2 stops24h 12m

$314

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Tue 8/12

4:23 pm-11:12 am

2 stops19h 49m

San José Juan Santamaria Intl

Tue 8/19

11:27 am-10:53 pm

1 stop10h 26m

$315

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Thu 9/18

10:35 am-11:14 am

1 stop25h 39m

San José Juan Santamaria Intl

Wed 10/22

12:19 pm-9:40 am

1 stop20h 21m

$317

Kansas CitySan Salvador

MCI - SAL

MCISAL

Kansas City

Sat 9/6

5:15 am-12:40 pm

2 stops32h 25m

San Salvador El Salvador Intl

Sun 9/21

1:45 pm-10:28 am

1 stop19h 43m

$338

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Mon 10/27

8:41 am-2:20 pm

1 stop6h 39m

Belize City Philip S.W.Goldson

Tue 11/4

1:12 pm-10:58 pm

1 stop9h 46m

$342

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 58 results
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Best time to book a flight from Missouri to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Central America

What is the cheapest month to book a flight from Missouri to Central America?

Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CA?

Find hourly flight availability from Missouri to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Central America as you normally would.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Missouri to Central America, such as Alaska Airlines, Southwest, and Delta. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Southwest
8.0
Very good
4,246 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
Copa Airlines
7.5
Good
1,493 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.
United Airlines
7.4
Good
8,900 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Food

7.1

Entertainment

7.1

Comfort

7.8

Boarding

8.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Jonathan,Jul 2025

SEA - BOS

Fantastic Check-in with easy baggage drop. While it took a while to find out which was the gate, the boarding was a dream, the stewards were simply incredible and the flight fantastic.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Central America one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $125. Spirit Airlines flights start at $134 while deals on United Airlines start at $164 one-way.

  • Can I find deals for flights from Missouri to Central America that include hotel bookings?

    Yes. In addition to deals on Missouri to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Central America.

  • Can I find deals for business class flights from Missouri to Central America?

    Yes. Cheapflights offers flight deals from Missouri to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Central America?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Central America

Discover the top 5 airlines that operate flights from Missouri to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$257Average$569FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$263Average$473FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$324Average$646FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$340Average$643FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$381Average$608FlexibilityNo cancel feeOn-time63%

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