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Central America

$106+ Cheap flights from Missouri to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Central America

Keep the following information in mind while searching for Missouri to Central America flight deals. Data was last updated May 1, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$231
(Cheapflightsfares)

One-way from

$106
(eDestinos)

Popular in

December

Cheapest in

September

Average price

$604
Provider with most accurate pricing for Kansas City-San Salvador El Salvador Intl flight deals.
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From Missouri to Central America
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One-way flight from Missouri to Central America
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Highest demand for flights based on searches. 24% potential increase in price ($195 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($54 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Missouri to Central America

Cheapest flights from Missouri to Central America
Explore the most affordable flight options available from Missouri to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2411:26 amMCI - GUA
1 stop13h 28mSpirit Airlines
Fri 5/3012:59 amGUA - MCI
1 stop8h 32mSpirit Airlines
Deal found 4/30$231
This Cheapflightsfares deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1710:10 amSTL - GUA
1 stop14h 44mSpirit Airlines
Sat 5/2412:59 amGUA - STL
1 stop7h 16mSpirit Airlines
Deal found 4/30$257
This FlightHub deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/282:45 pmMCI - SJO
2 stops21h 48mSpirit Airlines
Thu 6/511:32 amSJO - MCI
1 stop10h 09mSpirit Airlines
Deal found 5/1$287
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/175:45 pmSTL - GUA
2 stops18h 48mMultiple Airlines
Sat 5/2412:33 pmGUA - STL
1 stop19h 42mMultiple Airlines
Deal found 4/29$302
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/115:35 pmSTL - SJO
1 stop18h 02mMultiple Airlines
Wed 6/1811:32 amSJO - STL
1 stop11h 21mMultiple Airlines
Deal found 4/30$341
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/99:50 amSTL - SJO
1 stop10h 40mSouthwest
Thu 11/132:10 pmSJO - STL
1 stop8h 35mSouthwest
Deal found 4/29$342
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/174:58 pmSTL - BZE
2 stops18h 27mAmerican Airlines
Wed 6/2511:15 amBZE - STL
2 stops19h 59mAmerican Airlines
Deal found 4/29$348
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:15 pmSTL - BZE
1 stop16h 20mUnited Airlines
Thu 8/142:35 pmBZE - STL
1 stop6h 40mUnited Airlines
Deal found 4/29$364
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2811:13 amMCI - SJO
1 stop12h 04mAmerican Airlines
Thu 6/511:59 pmSJO - MCI
1 stop15h 57mAmerican Airlines
Deal found 5/1$368
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/77:00 amSTL - SJO
2 stops12h 35mAmerican Airlines
Wed 5/2811:59 pmSJO - STL
1 stop17h 22mAmerican Airlines
Deal found 4/30$373
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/96:00 amSTL - BZE
1 stop6h 42mDelta
Thu 10/161:07 pmBZE - STL
1 stop9h 32mDelta
Deal found 4/29$384
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/275:13 amSTL - LIR
1 stop9h 13mAmerican Airlines
Tue 6/312:45 pmLIR - STL
1 stop8h 34mAmerican Airlines
Deal found 4/30$385

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Missouri

Fly to

Central America

Route

Depart

Return

Price

Kansas CityGuatemala City

MCI - GUA

MCIGUA

Kansas City

Sat 5/24

11:26 am-11:54 pm

1 stop13h 28m

Guatemala City La Aurora

Fri 5/30

12:59 am-10:31 am

1 stop8h 32m

$231

St. LouisGuatemala City

STL - GUA

STLGUA

Lambert-St Louis

Sat 5/17

10:10 am-11:54 pm

1 stop14h 44m

Guatemala City La Aurora

Sat 5/24

12:59 am-9:15 am

1 stop7h 16m

$257

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Wed 5/28

2:45 pm-11:33 am

2 stops21h 48m

San José Juan Santamaria Intl

Thu 6/5

11:32 am-10:41 pm

1 stop10h 09m

$287

St. LouisGuatemala City

STL - GUA

STLGUA

Lambert-St Louis

Sat 5/17

5:45 pm-11:33 am

2 stops18h 48m

Guatemala City La Aurora

Sat 5/24

12:33 pm-9:15 am

1 stop19h 42m

$302

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Wed 6/11

5:35 pm-10:37 am

1 stop18h 02m

San José Juan Santamaria Intl

Wed 6/18

11:32 am-11:53 pm

1 stop11h 21m

$341

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Tue 6/17

4:58 pm-10:25 am

2 stops18h 27m

Belize City Philip S.W.Goldson

Wed 6/25

11:15 am-8:14 am

2 stops19h 59m

$348

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Fri 8/8

6:15 pm-9:35 am

1 stop16h 20m

Belize City Philip S.W.Goldson

Thu 8/14

2:35 pm-10:15 pm

1 stop6h 40m

$364

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

Wed 5/28

11:13 am-10:17 pm

1 stop12h 04m

San José Juan Santamaria Intl

Thu 6/5

11:59 pm-4:56 pm

1 stop15h 57m

$368

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

Wed 5/7

7:00 am-6:35 pm

2 stops12h 35m

San José Juan Santamaria Intl

Wed 5/28

6:03 am-9:26 pm

2 stops14h 23m

$373

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Thu 10/9

6:00 am-11:42 am

1 stop6h 42m

Belize City Philip S.W.Goldson

Thu 10/16

1:07 pm-11:39 pm

1 stop9h 32m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 58 results
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Best time to book a flight from Missouri to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Central America

What is the cheapest month to book a flight from Missouri to Central America?

Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CA?

Find hourly flight availability from Missouri to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated May 1, 2025.
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,972 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,294 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,934 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Copa Airlines
7.5
Good
1,414 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,972 reviews

Food

7.1

Comfort

7.9

Crew

8.5

Entertainment

7.1

Overall

8.0

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $106. American Airlines flights start at $129 while deals on United Airlines start at $154 one-way.

  • Can I find deals for flights from Missouri to Central America that include hotel bookings?

    Yes. In addition to deals on Missouri to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Central America.

  • Can I find deals for business class flights from Missouri to Central America?

    Yes. Cheapflights offers flight deals from Missouri to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Central America?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Central America

Discover the top 5 airlines that operate flights from Missouri to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$247Average$418FlexibilityNo cancel feeOn-time65%
DeltaCheapest$250Average$590FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$332Average$641FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$340Average$633FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$418Average$642FlexibilityNo cancel feeOn-time63%

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