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Central America

$102+ Cheap flights from Missouri to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Missouri to Central America

Keep the following information in mind while searching for Missouri to Central America flight deals. Data was last updated September 15, 2025.

Round-trip from

$246
(American Airlines)

One-way from

$102
(American Airlines)

Popular in

December

Cheapest in

May

Average price

$482
From Missouri to Central America
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One-way flight from Missouri to Central America
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Highest demand for flights based on searches. 27% potential increase in price ($214 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Missouri to Central America

Cheapest flights from Missouri to Central America
Explore the most affordable flight options available from Missouri to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:11 amSTL - BZE
1 stop10h 09mAmerican Airlines
Fri 10/243:30 pmBZE - STL
2 stops15h 46mAmerican Airlines
Deal found 9/14$246
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:15 amSTL - BZE
1 stop6h 20mUnited Airlines
Thu 10/92:35 pmBZE - STL
1 stop6h 25mUnited Airlines
Deal found 9/14$254
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:02 pmSTL - BZE
2 stops20h 48mAmerican Airlines
Thu 10/93:30 pmBZE - STL
1 stop7h 26mAmerican Airlines
Deal found 9/14$258
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3111:12 amMCI - SAL
1 stop25h 57mMultiple Airlines
Thu 11/133:03 pmSAL - MCI
1 stop20h 05mMultiple Airlines
Deal found 9/15$267
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amSTL - BZE
1 stop6h 25mDelta
Wed 10/2212:40 pmBZE - STL
1 stop8h 24mDelta
Deal found 9/14$276
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/206:00 amSTL - BZE
1 stop6h 25mDelta
Fri 10/2412:40 pmBZE - STL
1 stop10h 01mDelta
Deal found 9/14$284
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:05 pmSTL - BZE
2 stops19h 17mAmerican Airlines
Mon 10/203:30 pmBZE - STL
2 stops19h 41mAmerican Airlines
Deal found 9/15$292
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2311:37 amMCI - SAL
1 stop25h 47mFrontier
Sat 11/11:24 pmSAL - MCI
1 stop20h 53mFrontier
Deal found 9/14$301
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:37 amMCI - SAL
1 stop25h 47mFrontier
Sat 11/11:24 pmSAL - MCI
1 stop20h 53mFrontier
Deal found 9/14$306
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/205:11 pmMCI - SJO
1 stop19h 19mSpirit Airlines
Thu 10/2312:35 pmSJO - MCI
1 stop26h 41mSpirit Airlines
Deal found 9/15$307
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/278:41 amSTL - BZE
1 stop6h 39mAmerican Airlines
Tue 11/41:12 pmBZE - STL
1 stop9h 46mAmerican Airlines
Deal found 9/14$308
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:13 pmMCI - GUA
1 stop24h 13mSpirit Airlines
Thu 12/41:59 amGUA - MCI
1 stop9h 09mSpirit Airlines
Deal found 9/12$310

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Missouri

Fly to

Central America

Route

Depart

Return

Price

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Mon 10/6

6:15 am-11:35 am

1 stop6h 20m

Belize City Philip S.W.Goldson

Thu 10/9

2:35 pm-10:00 pm

1 stop6h 25m

$254

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Mon 10/20

6:00 am-11:25 am

1 stop6h 25m

Belize City Philip S.W.Goldson

Thu 10/23

12:40 pm-11:41 pm

1 stop10h 01m

$276

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Fri 10/17

8:05 pm-11:50 am

2 stops16h 45m

Belize City Philip S.W.Goldson

Mon 10/20

3:30 pm-11:56 pm

1 stop7h 26m

$292

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Mon 10/27

8:41 am-2:20 pm

1 stop6h 39m

Belize City Philip S.W.Goldson

Tue 11/4

1:12 pm-10:58 pm

1 stop9h 46m

$308

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 9/29

6:01 am-12:00 pm

1 stop6h 59m

Liberia

Fri 10/3

1:25 pm-11:24 pm

1 stop8h 59m

$315

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Fri 10/17

6:15 am-11:35 am

1 stop6h 20m

Belize City Philip S.W.Goldson

Mon 10/20

12:40 pm-10:00 pm

1 stop8h 20m

$315

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

Sun 10/19

6:00 am-11:25 am

1 stop6h 25m

Belize City Philip S.W.Goldson

Wed 10/22

12:40 pm-10:04 pm

1 stop8h 24m

$315

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Sat 11/29

6:45 pm-2:13 pm

2 stops19h 28m

Liberia

Fri 12/5

1:25 pm-11:59 pm

1 stop10h 34m

$319

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

Mon 9/29

2:11 pm-11:49 am

2 stops22h 38m

Liberia

Fri 10/3

12:49 pm-11:59 pm

1 stop10h 10m

$319

Kansas CityGuatemala City

MCI - GUA

MCIGUA

Kansas City

Wed 12/3

12:13 pm-12:55 am

1 stop12h 42m

Guatemala City La Aurora

Wed 12/10

12:11 pm-12:39 pm

1 stop24h 28m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Central America

What is the cheapest month to book a flight from Missouri to Central America?

Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CA?

Find hourly flight availability from Missouri to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Central America as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Central America?

    For as low as $254, United Airlines can have you in Central America from Missouri in 6h 20m. The distance between Missouri and Central America is about 1470 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Central America one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $102. Spirit Airlines flights start at $130 while deals on Frontier start at $175 one-way.

  • Can I find deals for flights from Missouri to Central America that include hotel bookings?

    Yes. In addition to deals on Missouri to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Central America.

  • Can I find deals for business class flights from Missouri to Central America?

    Yes. Cheapflights offers flight deals from Missouri to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Central America?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $554). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Central America

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Top 5 airlines flying from Missouri to Central America

Discover the top 5 airlines that operate flights from Missouri to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$557FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$263Average$416FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$326Average$647FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$353Average$642FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$629FlexibilityNo cancel feeOn-time63%

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