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Central America

$126+ Cheap flights from Missouri to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — SJO
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Missouri to Central America

Keep the following information in mind while searching for Missouri to Central America flight deals. Data was last updated junio 12, 2025.

Round-trip from

$256
(Cheapflightsfares)

One-way from

$126
(Priceline)

Popular in

December

Cheapest in

August

Average price

$590
From Missouri to Central America
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One-way flight from Missouri to Central America
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Highest demand for flights based on searches. 26% potential increase in price ($210 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($56 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Missouri to Central America

Cheapest flights from Missouri to Central America
Explore the most affordable flight options available from Missouri to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/126:04 pmMCI - GUA
1 stop7h 00mSpirit Airlines
vie. 7/1812:59 amGUA - MCI
1 stop15h 10mSpirit Airlines
Deal found 6/11$256
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/176:00 amSTL - SJO
1 stop6h 52mDelta
mar. 11/257:00 amSJO - STL
1 stop11h 02mDelta
Deal found 6/11$286
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/246:00 amSTL - BZE
1 stop6h 44mDelta
vie. 9/51:07 pmBZE - STL
1 stop7h 55mDelta
Deal found 6/10$288
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/295:29 amSTL - SJO
2 stops8h 31mAmerican Airlines
mar. 11/43:50 pmSJO - STL
1 stop16h 25mAmerican Airlines
Deal found 6/11$290
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/207:00 pmSTL - BZE
2 stops18h 20mAmerican Airlines
vie. 10/243:08 pmBZE - STL
1 stop16h 47mAmerican Airlines
Deal found 6/11$292
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/96:00 amSTL - LIR
1 stop7h 00mDelta
mar. 9/161:25 pmLIR - STL
1 stop7h 34mDelta
Deal found 6/11$295
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/95:28 amSTL - LIR
1 stop7h 21mAmerican Airlines
mar. 9/1612:49 pmLIR - STL
2 stops22h 34mAmerican Airlines
Deal found 6/11$299
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/197:10 amMCI - SJO
1 stop6h 30mSouthwest
vie. 10/241:30 pmSJO - MCI
1 stop9h 40mSouthwest
Deal found 6/12$300
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/136:12 pmMCI - SJO
2 stops17h 58mAmerican Airlines
mié. 10/222:25 pmSJO - MCI
2 stops20h 14mAmerican Airlines
Deal found 6/12$304
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 8/256:15 amSTL - BZE
1 stop6h 20mUnited Airlines
dom. 8/312:35 pmBZE - STL
1 stop6h 33mUnited Airlines
Deal found 6/11$335
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/146:00 amMCI - PTY
1 stop6h 47mDelta
mar. 10/212:12 pmPTY - MCI
1 stop9h 45mDelta
Deal found 6/12$337
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/246:15 amSTL - LIR
1 stop6h 55mUnited Airlines
lun. 9/291:20 pmLIR - STL
2 stops20h 29mUnited Airlines
Deal found 6/11$339

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Missouri to Central America that are best for you.

Fly from

Missouri

Fly to

Central America

Route

Depart

Return

Price

Kansas CityGuatemala City

MCI - GUA

MCIGUA

Kansas City

sáb. 7/12

6:04 pm-12:04 am

1 stop7h 00m

Guatemala City La Aurora

vie. 7/18

12:59 am-5:09 pm

1 stop15h 10m

$256

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

lun. 11/17

6:00 am-12:52 pm

1 stop6h 52m

San José Juan Santamaria Intl

mar. 11/25

7:00 am-6:02 pm

1 stop11h 02m

$286

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

dom. 8/24

6:00 am-11:44 am

1 stop6h 44m

Belize City Philip S.W.Goldson

vie. 9/5

1:07 pm-10:02 pm

1 stop7h 55m

$288

St. LouisSan José

STL - SJO

STLSJO

Lambert-St Louis

mié. 10/29

5:29 am-1:00 pm

2 stops8h 31m

San José Juan Santamaria Intl

mar. 11/4

3:50 pm-8:15 am

1 stop16h 25m

$290

St. LouisBelize City

STL - BZE

STLBZE

Lambert-St Louis

lun. 10/20

7:00 pm-12:20 pm

2 stops18h 20m

Belize City Philip S.W.Goldson

vie. 10/24

3:08 pm-8:55 am

1 stop16h 47m

$292

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

mar. 9/9

6:00 am-12:00 pm

1 stop7h 00m

Liberia

mar. 9/16

1:25 pm-9:59 pm

1 stop7h 34m

$295

St. LouisLiberia

STL - LIR

STLLIR

Lambert-St Louis

mar. 9/9

5:28 am-11:49 am

1 stop7h 21m

Liberia

mar. 9/16

12:49 pm-12:23 pm

2 stops22h 34m

$299

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

dom. 10/19

7:10 am-12:40 pm

1 stop6h 30m

San José Juan Santamaria Intl

vie. 10/24

1:30 pm-12:10 am

1 stop9h 40m

$300

Kansas CitySan José

MCI - SJO

MCISJO

Kansas City

lun. 10/13

6:12 pm-11:10 am

2 stops17h 58m

San José Juan Santamaria Intl

mié. 10/22

2:25 pm-11:39 am

2 stops20h 14m

$304

Kansas CityPanama City

MCI - PTY

MCIPTY

Kansas City

mar. 10/14

6:00 am-12:47 pm

1 stop6h 47m

Panama City Tocumen Intl

mar. 10/21

2:12 pm-11:57 pm

1 stop9h 45m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Central America

What is the cheapest month to book a flight from Missouri to Central America?

Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CA?

Find hourly flight availability from Missouri to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Central America as you normally would.

Rainfall in Central America by month

Plan your trip to Central America by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Central America ranges from 0.0 - 13.0 inches per month. August is typically the wettest month, when rainfall can reach 13.0 in. February is typically the driest time to visit Central America when rainfall is around 0.0 in.

Temperature in Central America by month

Plan your trip to Central America by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Central America, use this chart to help with planning. For those seeking warmer temperatures, March is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated junio 12, 2025.
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.
Southwest
8.0
Very good
4,287 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.
Delta
8.0
Very good
7,950 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.
Copa Airlines
7.5
Good
1,451 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Entertainment

7.1

Crew

8.5

Overall

8.0

Comfort

7.8

Boarding

8.1

Food

7.1

Reviews

1 / 20
10.0
Excellent

Surinder,May 2025

SEA - YYZ

My wife wanted the aile seat and I always prefer window seat. Luckily we both got the best seats we wanted. The plane was very nice and we enjoyed the best take off and the smooth landing at Toronto. All the services by the staff inside the aeroplane were very nice well appreciated. Thanks again and hope to see you soon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Missouri to Central America one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $126. American Airlines flights start at $132 while deals on Spirit Airlines start at $137 one-way.

  • Can I find deals for flights from Missouri to Central America that include hotel bookings?

    Yes. In addition to deals on Missouri to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Central America.

  • Can I find deals for business class flights from Missouri to Central America?

    Yes. Cheapflights offers flight deals from Missouri to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Central America?

    Currently, September is the cheapest month in which you can book a flight from Missouri to Central America (average of $398). Flying from Missouri to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Central America

Discover the top 5 airlines that operate flights from Missouri to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$247Average$437FlexibilityNo cancel feeOn-time65%
DeltaCheapest$250Average$563FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$332Average$648FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$340Average$631FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$418Average$618FlexibilityNo cancel feeOn-time63%

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