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Central America

$122+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/248:17 pmMEM - GUA
1 stop15h 08mSpirit Airlines
mar. 12/3012:20 pmGUA - MEM
1 stop7h 02mSpirit Airlines
Deal found 12/10$371
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/226:30 amMEM - LIR
1 stop12h 07mUnited Airlines
vie. 12/268:35 amLIR - MEM
1 stop13h 11mUnited Airlines
Deal found 12/10$385
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/225:12 amMEM - LIR
1 stop9h 15mAmerican Airlines
vie. 12/2611:55 amLIR - MEM
2 stops12h 01mAmerican Airlines
Deal found 12/10$389
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/199:00 amMEM - LIR
1 stop9h 37mUnited Airlines
mar. 12/238:35 amLIR - MEM
1 stop13h 11mUnited Airlines
Deal found 12/11$455
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/188:05 amMEM - LIR
1 stop6h 25mDelta
dom. 12/212:05 pmLIR - MEM
1 stop9h 06mDelta
Deal found 12/11$475
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/257:57 pmMEM - GUA
2 stops15h 28mMultiple Airlines
mar. 1/1312:15 pmGUA - MEM
1 stop22h 34mMultiple Airlines
Deal found 12/11$480
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1111:37 amMEM - SAL
1 stop9h 42mUnited Airlines
mié. 12/176:55 amSAL - MEM
1 stop7h 00mUnited Airlines
Deal found 12/11$484
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:21 pmMEM - LIR
1 stop17h 19mDelta
jue. 12/183:55 pmLIR - MEM
1 stop7h 28mDelta
Deal found 12/11$485
This CheapOair deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/238:17 pmMEM - GUA
1 stop15h 08mSpirit Airlines
jue. 1/13:00 pmGUA - MEM
1 stop28h 22mSpirit Airlines
Deal found 12/10$485
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/116:50 pmMEM - SAL
2 stops17h 36mAmerican Airlines
mié. 12/176:00 amSAL - MEM
2 stops14h 55mAmerican Airlines
Deal found 12/11$488
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/157:21 pmMEM - LIR
1 stop17h 19mDelta
sáb. 12/2012:35 pmLIR - MEM
1 stop7h 40mDelta
Deal found 12/11$505
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/296:42 pmMEM - LIR
1 stop16h 03mAmerican Airlines
jue. 1/11:27 pmLIR - MEM
1 stop10h 29mAmerican Airlines
Deal found 12/11$507

Find flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated diciembre 12, 2025.

Round-trip from

$302
(Kiwi.com)

One-way from

$122
(KAYAK)
From Mississippi to Central America
Search Deals
One-way flight from Mississippi to Central America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Mississippi to Central America that are best for you.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

sáb. 1/24

11:44 am-1:16 pm

2 stops25h 32m

Guatemala City La Aurora

jue. 1/29

12:15 pm-2:50 pm

1 stop26h 35m

$302

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

sáb. 1/24

11:44 am-2:52 pm

2 stops27h 08m

San Salvador El Salvador Intl

sáb. 2/7

2:51 pm-5:10 pm

1 stop26h 19m

$304

MemphisSan José

MEM - SJO

MEMSJO

Memphis

vie. 2/20

11:14 am-11:40 am

1 stop24h 26m

San José Juan Santamaria Intl

mar. 2/24

12:35 pm-10:19 am

1 stop21h 44m

$327

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

dom. 1/25

8:18 pm-12:29 pm

1 stop16h 11m

Guatemala City La Aurora

jue. 1/29

2:11 pm-2:50 pm

2 stops24h 39m

$328

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

mié. 1/21

11:44 am-1:16 pm

2 stops25h 32m

Guatemala City La Aurora

mié. 1/28

12:15 pm-10:49 am

1 stop22h 34m

$329

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

dom. 2/22

8:03 pm-12:10 pm

2 stops16h 07m

Liberia

jue. 2/26

3:18 pm-8:51 am

2 stops17h 33m

$331

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

vie. 1/23

3:40 pm-11:20 am

1 stop19h 40m

Guatemala City La Aurora

jue. 1/29

12:15 pm-2:50 pm

1 stop26h 35m

$331

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

dom. 1/25

6:00 am-2:13 pm

1 stop8h 13m

Liberia

dom. 2/1

3:13 pm-11:58 pm

1 stop8h 45m

$332

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

mié. 1/21

11:44 am-11:20 am

1 stop23h 36m

Guatemala City La Aurora

vie. 1/30

12:15 pm-10:49 am

1 stop22h 34m

$333

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

sáb. 1/24

11:44 am-11:20 am

1 stop23h 36m

Guatemala City La Aurora

vie. 1/30

12:15 pm-10:49 am

1 stop22h 34m

$333

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Central America

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, June is the cheapest month in which you can book a flight from Mississippi to Central America (average of $453). Flying from Mississippi to Central America in February is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

One of the essential ways to save on airfare from Mississippi to Central America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Central America?

    There are many flights that can get you from Mississippi to Central America in 7h. Fly via Spirit Airlines, American Airlines, or United Airlines to get the fastest option. The distance between Mississippi and Central America is about 1767 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, June is the cheapest month in which you can book a flight from Mississippi to Central America (average of $453). Flying from Mississippi to Central America in February is currently the most expensive (average of $572). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Central America

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Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$372Average$710FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$636FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$467Average$585FlexibilityNo cancel feeOn-time71%

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