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Central America

$111+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated September 11, 2025.

Round-trip from

$282
(Mytrip)

One-way from

$111
(Mytrip)
From Mississippi to Central America
Search Deals
One-way flight from Mississippi to Central America
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Find flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Mytrip deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/288:35 pmMEM - SJO
2 stops15h 39mMultiple Airlines
Sun 10/57:30 amSJO - MEM
1 stop14h 38mMultiple Airlines
Deal found 9/10$282
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/184:19 pmMEM - GUA
1 stop18h 57mMultiple Airlines
Mon 12/81:22 pmGUA - MEM
1 stop23h 10mMultiple Airlines
Deal found 9/9$308
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/184:19 pmMEM - GUA
1 stop18h 57mMultiple Airlines
Wed 12/31:22 pmGUA - MEM
1 stop27h 14mMultiple Airlines
Deal found 9/9$311
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:45 amMEM - LIR
1 stop11h 52mUnited Airlines
Thu 11/68:35 amLIR - MEM
1 stop13h 06mUnited Airlines
Deal found 9/10$313
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/268:17 amMEM - GUA
1 stop28h 05mMultiple Airlines
Sun 11/212:25 pmGUA - MEM
1 stop10h 43mMultiple Airlines
Deal found 9/10$315
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:51 pmMEM - LIR
2 stops19h 27mAmerican Airlines
Thu 11/203:13 pmLIR - MEM
2 stops18h 59mAmerican Airlines
Deal found 9/10$317
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/184:19 pmMEM - GUA
1 stop18h 57mSpirit Airlines
Sun 12/712:11 pmGUA - MEM
1 stop27h 03mSpirit Airlines
Deal found 9/9$322
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:00 amMEM - SJO
2 stops29h 30mMultiple Airlines
Sat 10/2512:35 pmSJO - MEM
1 stop17h 52mMultiple Airlines
Deal found 9/10$339
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:55 pmGPT - SJO
1 stop15h 46mMultiple Airlines
Thu 10/2311:37 amSJO - GPT
1 stop6h 38mMultiple Airlines
Deal found 9/11$349
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:25 amMEM - LIR
1 stop8h 37mAmerican Airlines
Fri 10/312:49 pmLIR - MEM
1 stop9h 34mAmerican Airlines
Deal found 9/10$355
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:51 pmGPT - SJO
2 stops17h 39mMultiple Airlines
Thu 10/2311:37 amSJO - GPT
1 stop6h 38mMultiple Airlines
Deal found 9/11$355
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/94:08 pmMEM - SJO
2 stops20h 22mMultiple Airlines
Thu 10/167:30 amSJO - MEM
1 stop14h 38mMultiple Airlines
Deal found 9/9$357

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Mississippi to Central America that are best for you.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sat 11/15

9:00 am-6:37 pm

1 stop9h 37m

Liberia

Thu 11/20

8:35 am-9:41 pm

1 stop13h 06m

$313

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Fri 10/31

6:45 am-5:37 pm

1 stop11h 52m

Liberia

Thu 11/6

8:35 am-9:41 pm

1 stop13h 06m

$313

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Sun 10/26

8:17 am-11:22 am

1 stop28h 05m

Guatemala City La Aurora

Sun 11/2

12:25 pm-11:08 pm

1 stop10h 43m

$315

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sat 11/15

6:36 pm-2:13 pm

2 stops19h 37m

Liberia

Thu 11/20

1:19 pm-11:59 pm

1 stop10h 40m

$317

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

Tue 11/18

4:19 pm-11:16 am

1 stop18h 57m

Guatemala City La Aurora

Thu 12/4

12:11 pm-3:14 pm

1 stop27h 03m

$322

GulfportSan José

GPT - SJO

GPTSJO

Gulfport Biloxi Regional

Sun 10/19

7:55 pm-10:41 am

1 stop15h 46m

San José Juan Santamaria Intl

Thu 10/23

11:37 am-7:15 pm

1 stop6h 38m

$349

MemphisSan José

MEM - SJO

MEMSJO

Memphis

Mon 9/22

6:38 pm-11:14 am

1 stop17h 36m

San José Juan Santamaria Intl

Sun 9/28

12:19 pm-5:43 pm

1 stop28h 24m

$358

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Fri 9/26

6:08 pm-11:49 am

2 stops18h 41m

Liberia

Fri 10/3

12:49 pm-10:04 am

2 stops20h 15m

$359

MemphisSan José

MEM - SJO

MEMSJO

Memphis

Tue 10/21

7:00 am-11:30 am

3 stops29h 30m

San José Juan Santamaria Intl

Sat 10/25

7:30 am-11:08 pm

1 stop14h 38m

$369

MemphisSan José

MEM - SJO

MEMSJO

Memphis

Thu 10/9

8:32 am-11:30 am

1 stop27h 58m

San José Juan Santamaria Intl

Thu 10/16

11:37 am-11:08 pm

1 stop10h 31m

$378

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 47 results
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Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Central America

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Central America as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Central America?

    There are many flights that can get you from Mississippi to Central America in 9h 37m. Fly via United Airlines, American Airlines, or Spirit Airlines to get the fastest option. The distance between Mississippi and Central America is about 1711 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $118. United Airlines flights start at $203 while deals on American Airlines start at $209 one-way.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Central America

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Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$366Average$668FlexibilityNo cancel feeOn-time69%
DeltaCheapest$372Average$880FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$608FlexibilityNo cancel feeOn-time71%

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