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Central America

$104+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated October 28, 2025.

Round-trip from

$279
(CheapOair)

One-way from

$104
(CheapOair)
From Mississippi to Central America
Search Deals
One-way flight from Mississippi to Central America
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Find flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This CheapOair deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmMEM - SAP
1 stop15h 19mSpirit Airlines
Wed 12/1711:56 amSAP - MEM
1 stop6h 51mSpirit Airlines
Deal found 10/26$279
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2711:20 amMEM - SAP
1 stop26h 50mMultiple Airlines
Mon 12/153:14 pmSAP - MEM
1 stop21h 18mMultiple Airlines
Deal found 10/26$301
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:55 pmMEM - SJO
1 stop14h 44mSpirit Airlines
Sat 11/221:20 pmSJO - MEM
2 stops20h 43mSpirit Airlines
Deal found 10/26$321
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:00 amMEM - SJO
1 stop16h 07mDelta
Sun 11/232:31 pmSJO - MEM
1 stop8h 33mDelta
Deal found 10/26$328
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/115:15 pmMEM - LIR
2 stops19h 10mAmerican Airlines
Thu 12/181:27 pmLIR - MEM
1 stop10h 29mAmerican Airlines
Deal found 10/27$331
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmMEM - SAP
2 stops18h 31mMultiple Airlines
Wed 12/171:31 pmSAP - MEM
2 stops21h 01mMultiple Airlines
Deal found 10/26$331
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:42 pmMEM - SAP
2 stops18h 31mSpirit Airlines
Thu 12/1811:56 amSAP - MEM
1 stop7h 26mSpirit Airlines
Deal found 10/27$336
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:42 pmMEM - SAP
2 stops18h 31mSpirit Airlines
Mon 1/121:53 amSAP - MEM
2 stops13h 21mSpirit Airlines
Deal found 10/26$340
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:42 pmMEM - SAP
1 stop15h 19mSpirit Airlines
Fri 12/2611:56 amSAP - MEM
1 stop7h 26mSpirit Airlines
Deal found 10/28$359
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/278:17 pmMEM - SJO
1 stop15h 25mMultiple Airlines
Wed 12/311:31 pmSJO - MEM
1 stop29h 36mMultiple Airlines
Deal found 10/26$362
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/97:25 pmMEM - GUA
1 stop15h 56mMultiple Airlines
Sat 11/1512:11 pmGUA - MEM
2 stops19h 21mMultiple Airlines
Deal found 10/26$362
This CheapOair deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:55 pmMEM - SAP
2 stops17h 15mSpirit Airlines
Wed 2/181:53 amSAP - MEM
1 stop8h 09mSpirit Airlines
Deal found 10/27$363

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Mississippi to Central America that are best for you.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Wed 12/10

7:42 pm-11:01 am

1 stop15h 19m

San Pedro Sula Ramon Villeda

Wed 12/17

11:56 am-6:47 pm

1 stop6h 51m

$279

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Sun 1/11

10:57 am-12:48 am

1 stop13h 51m

San Pedro Sula Ramon Villeda

Tue 1/13

1:53 am-3:14 pm

2 stops13h 21m

$286

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Thu 11/27

11:20 am-2:10 pm

1 stop26h 50m

San Pedro Sula Ramon Villeda

Mon 12/15

3:14 pm-12:32 pm

1 stop21h 18m

$301

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Thu 12/11

6:33 pm-12:19 pm

2 stops17h 46m

Liberia

Thu 12/18

11:55 am-11:56 pm

2 stops12h 01m

$331

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Wed 12/10

7:42 pm-2:13 pm

2 stops18h 31m

San Pedro Sula Ramon Villeda

Wed 12/17

1:31 pm-10:32 am

2 stops21h 01m

$331

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Sun 1/11

10:57 am-12:48 am

1 stop13h 51m

San Pedro Sula Ramon Villeda

Wed 1/14

11:48 am-9:50 am

2 stops22h 02m

$334

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sun 2/22

7:00 am-2:30 pm

1 stop7h 30m

Liberia

Thu 2/26

3:55 pm-10:52 pm

1 stop6h 57m

$335

MemphisSan Pedro Sula

MEM - SAP

MEMSAP

Memphis

Thu 12/11

7:42 pm-2:13 pm

2 stops18h 31m

San Pedro Sula Ramon Villeda

Thu 12/18

11:56 am-7:22 pm

1 stop7h 26m

$336

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sun 2/22

6:04 pm-12:12 pm

2 stops18h 08m

Liberia

Thu 2/26

1:15 pm-8:16 am

2 stops19h 01m

$339

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

Sun 4/19

8:07 pm-1:10 pm

2 stops18h 03m

Liberia

Tue 4/28

1:55 pm-9:55 am

2 stops19h 00m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 60 results
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Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Central America

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, June is the cheapest month in which you can book a flight from Mississippi to Central America (average of $453). Flying from Mississippi to Central America in February is currently the most expensive (average of $565). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

One of the essential ways to save on airfare from Mississippi to Central America is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

What is the cheapest day to fly from Mississippi to Central America?

Use this chart to determine the cheapest time to fly round-trip from Mississippi to Central America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mississippi to Central America flight should consider departing on Friday mornings when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to Central America?

    There are many flights that can get you from Mississippi to Central America in 7h 30m. Fly via Spirit Airlines, American Airlines, or Delta to get the fastest option. The distance between Mississippi and Central America is about 1711 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Mississippi to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $104. American Airlines flights start at $193 while deals on United Airlines start at $203 one-way.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, June is the cheapest month in which you can book a flight from Mississippi to Central America (average of $453). Flying from Mississippi to Central America in February is currently the most expensive (average of $565). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to Central America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$372Average$880FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$414Average$645FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$467Average$578FlexibilityNo cancel feeOn-time71%

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