HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Central America

$91+ Cheap flights from Mississippi to Central America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — SJO
ago. 3 — ago. 101
dom. 8/3
dom. 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Central America with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Central America

Keep the following information in mind while searching for Mississippi to Central America flight deals. Data was last updated julio 29, 2025.

Round-trip from

$280
(Mytrip)

One-way from

$91
(CheapOair)
From Mississippi to Central America
Search Deals
One-way flight from Mississippi to Central America
Search Deals

Find flight deals from Mississippi to Central America

Cheapest flights from Mississippi to Central America
Explore the most affordable flight options available from Mississippi to Central America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 29, 2025.

This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/72:41 pmMEM - GUA
1 stop10h 23mMultiple Airlines
lun. 8/1112:59 amGUA - MEM
1 stop9h 23mMultiple Airlines
Deal found 7/29$269
This Mytrip deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/117:00 amMEM - SJO
1 stop9h 13mMultiple Airlines
dom. 9/1411:37 amSJO - MEM
1 stop11h 08mMultiple Airlines
Deal found 7/28$280
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/48:35 pmMEM - SJO
1 stop14h 52mSpirit Airlines
jue. 9/1111:37 amSJO - MEM
1 stop11h 08mSpirit Airlines
Deal found 7/27$287
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/72:41 pmMEM - GUA
1 stop10h 23mSpirit Airlines
lun. 8/1112:59 amGUA - MEM
2 stops14h 30mSpirit Airlines
Deal found 7/29$299
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/229:37 amMEM - SJO
1 stop9h 20mAmerican Airlines
dom. 9/287:00 amSJO - MEM
1 stop14h 38mAmerican Airlines
Deal found 7/29$321
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/1212:12 pmMEM - SAL
2 stops31h 13mMultiple Airlines
jue. 8/211:19 pmSAL - MEM
1 stop28h 08mMultiple Airlines
Deal found 7/27$339
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/2712:15 pmBTR - SJO
1 stop6h 42mAmerican Airlines
mar. 9/307:27 amSJO - BTR
1 stop9h 36mAmerican Airlines
Deal found 7/28$380
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/125:34 pmMEM - SAL
2 stops43h 40mSpirit Airlines
jue. 8/211:19 pmSAL - MEM
1 stop28h 08mSpirit Airlines
Deal found 7/27$406
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/1011:39 amMEM - SAL
1 stop9h 38mUnited Airlines
mié. 9/173:30 pmSAL - MEM
1 stop16h 45mUnited Airlines
Deal found 7/26$411
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/96:15 pmMEM - SAL
1 stop18h 25mAmerican Airlines
mar. 10/1412:41 pmSAL - MEM
1 stop10h 18mAmerican Airlines
Deal found 7/27$412
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 9/275:02 pmMEM - BZE
2 stops20h 30mAmerican Airlines
lun. 10/1312:50 pmBZE - MEM
1 stop7h 09mAmerican Airlines
Deal found 7/29$439
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/257:00 amMEM - GUA
1 stop10h 32mUnited Airlines
lun. 9/291:30 amGUA - MEM
1 stop11h 23mUnited Airlines
Deal found 7/28$452

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Central America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 29, 2025.
Use the filters below to find and compare flights from Mississippi to Central America that are best for you.

Fly from

Mississippi

Fly to

Central America

Route

Depart

Return

Price

MemphisSan José

MEM - SJO

MEMSJO

Memphis

jue. 9/11

7:00 am-3:13 pm

1 stop9h 13m

San José Juan Santamaria Intl

dom. 9/14

11:37 am-11:45 pm

1 stop11h 08m

$280

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

mié. 8/27

7:00 am-11:29 pm

2 stops17h 29m

Guatemala City La Aurora

mié. 9/3

12:18 pm-7:53 am

1 stop18h 35m

$285

MemphisSan José

MEM - SJO

MEMSJO

Memphis

jue. 9/4

8:35 pm-10:27 am

1 stop14h 52m

San José Juan Santamaria Intl

jue. 9/11

11:37 am-11:45 pm

1 stop11h 08m

$287

MemphisGuatemala City

MEM - GUA

MEMGUA

Memphis

mié. 8/27

7:00 am-11:29 pm

2 stops17h 29m

Guatemala City La Aurora

mié. 9/3

12:18 pm-11:45 pm

2 stops34h 27m

$311

MemphisSan José

MEM - SJO

MEMSJO

Memphis

lun. 9/22

9:37 am-5:57 pm

1 stop9h 20m

San José Juan Santamaria Intl

dom. 9/28

7:00 am-10:38 pm

1 stop14h 38m

$321

MemphisLiberia

MEM - LIR

MEMLIR

Memphis

mié. 1/21

5:54 pm-12:20 pm

2 stops18h 26m

Liberia

mié. 1/28

3:55 pm-11:34 am

2 stops19h 39m

$339

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

mar. 8/12

12:12 pm-6:25 pm

2 stops31h 13m

San Salvador El Salvador Intl

jue. 8/21

1:19 pm-6:27 pm

1 stop28h 08m

$339

Baton RougeSan José

BTR - SJO

BTRSJO

Baton Rouge Ryan

sáb. 9/27

12:15 pm-5:57 pm

1 stop6h 42m

San José Juan Santamaria Intl

mar. 9/30

7:27 am-6:03 pm

1 stop9h 36m

$380

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

mar. 8/12

5:34 pm-12:14 pm

2 stops43h 40m

San Salvador El Salvador Intl

jue. 8/21

1:19 pm-6:27 pm

1 stop28h 08m

$406

MemphisSan Salvador

MEM - SAL

MEMSAL

Memphis

mié. 9/10

11:39 am-8:17 pm

1 stop9h 38m

San Salvador El Salvador Intl

mié. 9/17

3:30 pm-9:15 am

1 stop16h 45m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Showing 1-10 of 47 results
1
2
3
...
5

Best time to book a flight from Mississippi to Central America

Have a flexible travel schedule? Discover the best time to fly to Central America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Central America

What is the cheapest month to book a flight from Mississippi to Central America?

Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS to CA?

Find hourly flight availability from Mississippi to Central America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 29, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mississippi to Central America as you normally would.

Reviews of airlines servicing Central America

Get insights into the airlines that provide service to Central America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Central America. Reviews last updated julio 29, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and United Airlines from Mississippi to Central America by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,238 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,977 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,899 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
WestJet
7.2
Good
2,973 reviews
Southwest
8.0
Very good
4,238 reviews

Food

7.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Central America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from Mississippi to Central America one-way?

    To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $91. American Airlines flights start at $142 while deals on United Airlines start at $207 one-way.

  • Can I find deals for flights from Mississippi to Central America that include hotel bookings?

    Yes. In addition to deals on Mississippi to Central America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Central America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Central America.

  • Can I find deals for business class flights from Mississippi to Central America?

    Yes. Cheapflights offers flight deals from Mississippi to Central America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Central America?

    Currently, September is the cheapest month in which you can book a flight from Mississippi to Central America (average of $398). Flying from Mississippi to Central America in March is currently the most expensive (average of $555). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Central America

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Los Angeles flights
John F Kennedy Intl to Las Vegas flights
Newark to Heathrow flights
John F Kennedy Intl to Heathrow flights
Los Angeles to Newark flights
John F Kennedy Intl to Luis Munoz Marin Intl flights
Los Angeles to Haneda flights
Newark to Fort Lauderdale flights
Dallas/Fort Worth to Las Vegas flights
John F Kennedy Intl to Cancún flights
Newark to O'Hare Intl flights
Dallas/Fort Worth to O'Hare Intl flights
Newark to Los Angeles flights
John F Kennedy Intl to Miami flights
Newark to Miami flights
Newark to Cancún flights
LaGuardia to Fort Lauderdale flights
John F Kennedy Intl to O'Hare Intl flights
Los Angeles to Honolulu flights
John F Kennedy Intl to Orlando flights
Dallas/Fort Worth to Seattle flights
Newark to Orlando flights
O'Hare Intl to John F Kennedy Intl flights
San Francisco to John F Kennedy Intl flights
Los Angeles to Seattle flights
Dallas/Fort Worth to LaGuardia flights
LaGuardia to Miami flights
LaGuardia to O'Hare Intl flights
John F Kennedy Intl to San Francisco flights
Newark to Luis Munoz Marin Intl flights
John F Kennedy Intl to Seattle flights
Atlanta to John F Kennedy Intl flights
San Francisco to Newark flights
LaGuardia to Dallas/Fort Worth flights
San Francisco to Seattle flights
John F Kennedy Intl to Atlanta flights
O'Hare Intl to Newark flights
John F Kennedy Intl to Charles de Gaulle flights
O'Hare Intl to Cancún flights
O'Hare Intl to LaGuardia flights
John F Kennedy Intl to Fort Lauderdale flights
Dallas/Fort Worth to John F Kennedy Intl flights
O'Hare Intl to Dallas/Fort Worth flights
Los Angeles to Narita flights
Newark to Las Vegas flights
John F Kennedy Intl to Haneda flights
Newark to San Francisco flights
Dallas/Fort Worth to Los Angeles flights
Newark to Seattle flights

Top 3 airlines flying from Mississippi to Central America

Discover the top 3 airlines that operate flights from Mississippi to Central America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$366Average$662FlexibilityNo cancel feeOn-time69%
DeltaCheapest$372Average$918FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$596FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.