$129+ Cheap flights from Louisville (SDF) to Spartanburg, SC
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — CLT
Oct 4 — Oct 111
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Spartanburg with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Spartanburg
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Cheapest flights from Louisville to SpartanburgExplore the most affordable flight options available from Louisville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
Explore the most affordable flight options available from Louisville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:10 pm -
1 stop23h 03m
Tue 11/35:37 pm -
2 stops21h 49m
Deal found 8/31![Multiple Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am -
1 stop4h 45m
Tue 10/66:40 am -
1 stop5h 35m
Deal found 9/1![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:26 pm -
1 stop3h 35m
Thu 10/225:30 am -
1 stop3h 27m
Deal found 9/3![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:00 pm -
1 stop5h 00m
Fri 10/168:05 pm -
1 stop4h 10m
Deal found 9/1![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:15 pm -
2 stops8h 15m
Tue 10/61:15 pm -
2 stops7h 20m
Deal found 9/1![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:00 pm -
1 stop5h 25m
Thu 11/196:40 am -
1 stop5h 35m
Deal found 9/1![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop4h 45m
Fri 10/210:40 am -
2 stops10h 25m
Deal found 9/3![Southwest logo]()
$344
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:24 pm -
1 stop15h 11m
Sun 9/205:38 pm -
1 stop16h 47m
Deal found 8/30![Multiple Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:50 am -
1 stop4h 35m
Fri 9/186:15 pm -
1 stop4h 25m
Deal found 9/1![Southwest logo]()
$353
Best flights from Louisville to SpartanburgDiscover carefully curated flight deals from Louisville to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
Discover carefully curated flight deals from Louisville to Spartanburg that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 4, 2026.
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:35 pm -
1 stop5h 20m
Thu 1/141:30 pm -
1 stop8h 35m
Deal found 9/3![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:55 pm -
1 stop4h 04m
Fri 9/185:30 am -
1 stop3h 21m
Deal found 9/2![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop4h 45m
Fri 10/210:40 am -
2 stops10h 25m
Deal found 9/3![Southwest logo]()
$344
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:45 am -
1 stop4h 10m
Fri 10/910:40 am -
2 stops10h 30m
Deal found 9/1![Southwest logo]()
$364
This Southwest deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:15 pm -
1 stop4h 35m
Mon 10/128:05 pm -
1 stop4h 10m
Deal found 8/30![Southwest logo]()
$387
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:05 am -
1 stop6h 00m
Mon 10/511:15 am -
2 stops9h 55m
Deal found 8/31![Southwest logo]()
$411
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop4h 45m
Mon 10/511:15 am -
2 stops9h 55m
Deal found 8/31![Southwest logo]()
$411
This Southwest deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:15 pm -
1 stop4h 30m
Thu 10/810:40 am -
2 stops10h 30m
Deal found 8/31![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:20 pm -
1 stop6h 35m
Tue 10/66:40 am -
1 stop5h 35m
Deal found 9/1![Southwest logo]()
$431
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:50 pm -
1 stop5h 35m
Thu 10/810:40 am -
2 stops10h 30m
Deal found 9/3![Southwest logo]()
$452
Last-minute flights from Louisville to SpartanburgDiscover last-minute flight deals from Louisville to Spartanburg. Data last updated September 4, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Spartanburg. Data last updated September 4, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:05 am -
1 stop5h 05m
Mon 9/76:00 am -
1 stop4h 32m
Deal found 9/2![Delta logo]()
$357
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:04 am -
1 stop5h 07m
Sat 9/122:25 pm -
1 stop5h 05m
Deal found 9/3![Delta logo]()
$347
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:50 am -
1 stop4h 35m
Fri 9/186:15 pm -
1 stop4h 25m
Deal found 9/1![Southwest logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:24 pm -
1 stop15h 11m
Sun 9/205:38 pm -
1 stop16h 47m
Deal found 8/30![Multiple Airlines logo]()
$352
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:30 am -
1 stop4h 45m
Tue 10/66:40 am -
1 stop5h 35m
Deal found 9/1![Southwest logo]()
$331
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:15 pm -
2 stops8h 15m
Tue 10/61:15 pm -
2 stops7h 20m
Deal found 9/1![Southwest logo]()
$341
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop4h 45m
Fri 10/210:40 am -
2 stops10h 25m
Deal found 9/3![Southwest logo]()
$344
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:00 pm -
1 stop5h 00m
Fri 10/168:05 pm -
1 stop4h 10m
Deal found 9/1![Southwest logo]()
$339
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:26 pm -
1 stop3h 35m
Sat 10/247:36 am -
1 stop5h 18m
Deal found 9/3![Delta logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:10 pm -
1 stop23h 03m
Tue 11/35:37 pm -
2 stops21h 49m
Deal found 8/31![Multiple Airlines logo]()
$319
One-way flights from Louisville to SpartanburgSearch for one-way flight options from Louisville to Spartanburg. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
Search for one-way flight options from Louisville to Spartanburg. Find affordable one-way fares based on user searches. Data last updated September 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:54 pm -
1 stop23h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:10 pm -
1 stop23h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/30![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:56 am -
2 stops21h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$161
This Southwest deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:30 am -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Southwest logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/309:11 pm -
2 stops35h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:38 pm -
1 stop24h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$169
This Southwest deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/18:40 am -
2 stops12h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Southwest logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:11 pm -
2 stops35h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/1![Multiple Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop4h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Delta logo]()
$174
Find flight deals from Louisville to Spartanburg
Keep the following information in mind while searching for Louisville to Spartanburg flight deals. Data was last updated September 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $319 (Kiwi.com) |
One-way from | $129 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $455 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
Use the filters below to find and compare flights from Louisville to Spartanburg that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Sat 10/31
5:35 am-9:50 am
1 stop4h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$166
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Thu 12/3
2:05 pm-9:20 pm
1 stop7h 15m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$166
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Thu 11/26
6:45 am-12:15 pm
1 stop5h 30m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$166
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Tue 11/3
8:50 am-8:00 pm
2 stops11h 10m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$171
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Fri 9/11
6:00 am-10:12 am
1 stop4h 12m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Sat 12/5
5:59 pm-11:56 pm
1 stop5h 57m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Mon 11/2
3:26 pm-8:14 pm
1 stop4h 48m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Wed 12/2
1:04 pm-6:13 pm
1 stop5h 09m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$179
Quickest round-trip
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Fri 9/18
7:55 pm-11:59 pm
1 stop4h 04m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$184
LouisvilleCharlotte
SDF Louisville Intl - CLT Charlotte Douglas
SDFCLT
Louisville Intl
Wed 9/30
10:50 am-9:30 pm
2 stops10h 40m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$199
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Louisville to Spartanburg
Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Louisville with our price prediction graph.
SDF-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Spartanburg
SDF-SB1
SDF-CLT
What is the cheapest time of day to fly from SDF to SB1?
Find hourly flight availability from Louisville to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 4, 2026.
Unlike in the afternoon, when flights are generally more expensive, you can save up to 21% on flights from Louisville to Spartanburg by exploring options for tickets at noon.
How much does it cost to fly round-trip from Louisville to Spartanburg?
Airfare is below average for this route at the moment.
Louisville to Spartanburg flights typically cost between $404 and $493 in October.The cheapest round-trip price found within the last 5 days was $319 on Multiple Airlines (Oct 30-Nov 3).
What is the cheapest day to fly from Louisville to Spartanburg?
Use this chart to determine the cheapest time to fly round-trip from Louisville to Spartanburg. Price data was last updated on August 29, 2026.
Travelers seeking maximum savings on their Louisville to Spartanburg flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Spartanburg
Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated September 4, 2026.
Read through reviews of airlines operating flights from Louisville to Spartanburg, such as Southwest and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Louisville to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Spartanburg by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Louisville to Spartanburg, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Spartanburg flights
Browse other Louisville and Spartanburg flight options. Last updated on September 4, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on September 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Louisville to Spartanburg flights
Consider these flights traveling from Louisville to Spartanburg.
Top 3 airlines flying from Louisville to Spartanburg
Discover the top 3 airlines that operate flights from Louisville to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$279 | Average$413 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$314 | Average$414 | FlexibilityNo cancel fee | On-time63% |