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Spartanburg

$115+ Cheap flights from Knoxville (TYS) to Spartanburg, SC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CLT
Jul 16 — Jul 231
Wed 7/16
Wed 7/23
1 adult, Economy
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Cheap flight deals from Knoxville to Spartanburg

Keep the following information in mind while searching for Knoxville to Spartanburg flight deals. Data was last updated July 11, 2025.

Round-trip from

$237
(Mytrip)

One-way from

$115
(FlightHub)

Popular in

June

Cheapest in

April

Average price

$583
From Knoxville McGhee Tyson to Spartanburg
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One-way flight from Knoxville McGhee Tyson to Spartanburg
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Highest demand for flights based on searches. 10% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Knoxville to Spartanburg

Cheapest flights from Knoxville to Spartanburg
Explore the most affordable flight options available from Knoxville to Spartanburg. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2025.

This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/58:20 amTYS - CLT
2 stops24h 06mMultiple Airlines
Tue 8/126:20 amCLT - TYS
1 stop11h 39mMultiple Airlines
Deal found 7/8$240
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/15:19 pmTYS - CLT
1 stop25h 46mAmerican Airlines
Sun 8/38:14 amCLT - TYS
1 stop9h 25mAmerican Airlines
Deal found 7/10$367

Cheapflights Fare Finder

Customize your flight search to find flights from Knoxville to Spartanburg that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
Use the filters below to find and compare flights from Knoxville to Spartanburg that are best for you.

Fly from

Knoxville

Fly to

Spartanburg

Route

Depart

Return

Price

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Tue 8/5

8:20 am-8:26 am

2 stops24h 06m

Charlotte Douglas

Tue 8/12

6:20 am-5:59 pm

1 stop11h 39m

$240

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 8/1

5:19 pm-7:05 pm

1 stop25h 46m

Charlotte Douglas

Sun 8/3

8:14 am-5:39 pm

1 stop9h 25m

$367

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Mon 8/18

7:15 am-2:05 pm

1 stop6h 50m

$124

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 8/8

5:12 pm-6:29 am

1 stop13h 17m

$173

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Fri 8/8

6:00 pm-10:03 am

1 stop16h 03m

$179

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Sun 9/7

8:26 pm-4:25 pm

1 stop19h 59m

$205

KnoxvilleCharlotte

TYS - CLT

TYSCLT

Knoxville McGhee Tyson

Thu 8/7

10:55 am-9:45 pm

1 stop10h 50m

$338

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/8

Best time to book a flight from Knoxville to Spartanburg

Have a flexible travel schedule? Discover the best time to fly to Spartanburg from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Spartanburg

What is the cheapest month to book a flight from Knoxville to Spartanburg?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to SB1?

Find hourly flight availability from Knoxville to Spartanburg. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 11, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Spartanburg as you normally would.

What is the cheapest day to fly from Knoxville to Spartanburg?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to Spartanburg. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Knoxville to Spartanburg flight should consider departing on Thursday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Knoxville to Spartanburg

Explore weekly flight availability from Knoxville to Spartanburg. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 11, 2025.

The most flights from TYS to SB1 are scheduled on a Monday (7 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing Spartanburg

Get insights into the airlines that provide service to Spartanburg. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Spartanburg. Reviews last updated July 11, 2025.
Read through reviews of airlines operating flights from Knoxville to Spartanburg, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,951 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,846 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Frontier
5.9
Fair
3,271 reviews
Delta
8.0
Very good
7,951 reviews

Crew

8.5

Boarding

8.2

Overall

8.0

Food

7.3

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Spartanburg. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Spartanburg?

    If you book a flight to Spartanburg from Knoxville, you will be flying from McGhee Tyson, which is the city’s only airport. Knoxville McGhee Tyson (TYS) is located 11.3 mi from the center of Knoxville. There are 6 flights from McGhee Tyson to Spartanburg per day from 2 different airlines.

  • What are the cheapest airlines to fly from Knoxville to Spartanburg one-way?

    The cheapest airlines for a one-way flight from Knoxville to Spartanburg are Frontier ($115), Delta ($179), and American Airlines ($189).

  • What are the most reliable airlines from Knoxville to Spartanburg?

    Before booking your flight to Spartanburg from Knoxville, check out the most reliable airlines to get you to your destination on time: Envoy Air (100%), American Airlines (67%), Piedmont Airlines( 66%).

  • What are the cheapest flights from Knoxville to Spartanburg?

    The cheapest flight price from Knoxville to Spartanburg is $148. On average you can expect to pay $586. The most popular route, (Knoxville McGhee Tyson - Charlotte Douglas), can usually be booked for $228.

  • Can I find deals for flights from Knoxville to Spartanburg that include hotel bookings?

    Yes. In addition to deals on Knoxville to Spartanburg flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Spartanburg?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Spartanburg.

  • Can I find deals for business class flights from Knoxville to Spartanburg?

    Yes. Cheapflights offers flight deals from Knoxville to Spartanburg by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Spartanburg?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Spartanburg (average of $248). Flying from Knoxville to Spartanburg in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Knoxville to Spartanburg

Discover the top 2 airlines that operate flights from Knoxville to Spartanburg. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$532FlexibilityNo cancel feeOn-time71%
DeltaCheapest$286Average$334FlexibilityNo cancel feeOn-timeN/A

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