Weekly flight availability from Spartanburg to Knoxville

The most flights from SB1 to TYS are scheduled on a Monday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the most reliable airlines from Spartanburg to Knoxville?

The top 3 most reliable airlines when flying from Spartanburg to Knoxville are Piedmont Airlines (79%), British Airways (71%) and American Airlines (71%).

What airport do you fly into for flights to Knoxville from Spartanburg?

Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from Spartanburg to Knoxville. 1 airline have flights to McGhee Tyson from Spartanburg on a regular basis. Booking flights from Spartanburg to Knoxville McGhee Tyson should not be difficult; the airport handles an average of 10 inbound flights from Spartanburg per day.

Can I find deals for flights from Spartanburg to Knoxville that include hotel bookings?

Yes. In addition to deals on Spartanburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Spartanburg to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Knoxville.

Can I find deals for business class flights from Spartanburg to Knoxville?

Yes. Cheapflights offers flight deals from Spartanburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Spartanburg to Knoxville

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Highest demand for flights based on searches. 12% potential increase in price ($86 potential increase over avg. RT price).

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What is the cheapest time of day to fly from SB1 to TYS?

It’s typically best to fly out from Spartanburg to Knoxville in the morning. Doing so could potentially save you 27% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown American Airlines from Spartanburg to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

American Airlines

7.0

Good

12,186 reviews

Reviews

1 / 20

10.0

Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

American Airlines

7.0

Good

12,186 reviews

American Airlines

7.0

Good

12,186 reviews

Reviews

1 / 20

10.0

Excellent

Linda,Jul 2026

ROA - CLT

Very helpful and friendly people who pushed me where I needed to go

Related info for your journey

What airport do you fly into for flights to Knoxville from Spartanburg?
Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly into when you book flights from Spartanburg to Knoxville. 1 airline have flights to McGhee Tyson from Spartanburg on a regular basis. Booking flights from Spartanburg to Knoxville McGhee Tyson should not be difficult; the airport handles an average of 10 inbound flights from Spartanburg per day.
What are the most reliable airlines from Spartanburg to Knoxville?
The top 3 most reliable airlines when flying from Spartanburg to Knoxville are Piedmont Airlines (79%), British Airways (71%) and American Airlines (71%).
Can I find deals for flights from Spartanburg to Knoxville that include hotel bookings?
Yes. In addition to deals on Spartanburg to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Spartanburg to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Knoxville.
Can I find deals for business class flights from Spartanburg to Knoxville?
Yes. Cheapflights offers flight deals from Spartanburg to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top airline flying from Spartanburg to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$505	Average$575	FlexibilityNo cancel fee	On-time71%

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Cheap flights from Spartanburg, SC to Knoxville (TYS)

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What is the cheapest time of day to fly from SB1 to TYS?

It’s typically best to fly out from Spartanburg to Knoxville in the morning. Doing so could potentially save you 27% on the flight price compared to flying in the evening, which is usually more expensive.

Weekly flight availability from Spartanburg to Knoxville

The most flights from SB1 to TYS are scheduled on a Monday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (9 on average).

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown American Airlines from Spartanburg to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly into for flights to Knoxville from Spartanburg?

What are the most reliable airlines from Spartanburg to Knoxville?

Can I find deals for flights from Spartanburg to Knoxville that include hotel bookings?

How can I find direct flights from Spartanburg to Knoxville?

Can I find deals for business class flights from Spartanburg to Knoxville?

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Other flights to Knoxville

Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 22, 2026.

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