$123+ Cheap flights from Spartanburg, SC to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — TYS
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Spartanburg to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Spartanburg to Knoxville
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Cheapest flights from Spartanburg to KnoxvilleExplore the most affordable flight options available from Spartanburg to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Spartanburg to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:08 pm -
1 stop11h 57m
Mon 10/59:28 pm -
1 stop11h 07m
Deal found 9/3![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:59 pm -
2 stops27h 31m
Fri 10/239:28 pm -
1 stop21h 45m
Deal found 9/4![Multiple Airlines logo]()
$282
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:32 am -
1 stop8h 18m
Wed 10/76:41 pm -
1 stop13h 56m
Deal found 9/5![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:32 am -
1 stop7h 11m
Wed 9/3010:28 am -
1 stop22h 07m
Deal found 9/6![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:08 pm -
1 stop13h 56m
Wed 9/3010:28 am -
1 stop22h 07m
Deal found 9/6![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:08 pm -
1 stop11h 57m
Sat 10/109:36 pm -
1 stop22h 19m
Deal found 9/5![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:56 am -
1 stop27h 36m
Sat 9/123:51 pm -
1 stop16h 44m
Deal found 9/2![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 pm -
1 stop13h 56m
Sat 9/193:51 pm -
1 stop16h 44m
Deal found 9/3![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 pm -
1 stop13h 56m
Thu 9/175:38 pm -
1 stop14h 57m
Deal found 9/3![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:51 pm -
1 stop7h 30m
Sat 10/109:36 pm -
1 stop22h 19m
Deal found 9/6![Multiple Airlines logo]()
$346
Best flights from Spartanburg to KnoxvilleDiscover carefully curated flight deals from Spartanburg to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Spartanburg to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:55 am -
2 stops9h 55m
Mon 10/57:25 pm -
1 stop3h 25m
Deal found 9/3![Southwest logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:32 am -
1 stop8h 18m
Wed 10/71:51 pm -
2 stops18h 41m
Deal found 9/5![Multiple Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop8h 42m
Sat 9/267:25 pm -
1 stop18h 55m
Deal found 9/2![United Airlines logo]()
$565
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:25 pm -
1 stop9h 10m
Fri 11/277:25 pm -
1 stop3h 15m
Deal found 9/4![Southwest logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:42 pm -
1 stop14h 32m
Sun 10/259:15 am -
1 stop10h 40m
Deal found 9/5![Multiple Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:15 am -
2 stops9h 50m
Wed 10/77:15 am -
2 stops10h 10m
Deal found 9/5![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2311:10 am -
2 stops8h 45m
Sat 9/266:50 am -
1 stop7h 35m
Deal found 9/6![Southwest logo]()
$478
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:50 pm -
1 stop18h 35m
Mon 12/76:20 am -
2 stops17h 24m
Deal found 9/3![United Airlines logo]()
$613
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/511:30 am -
2 stops9h 00m
Sun 11/87:25 pm -
1 stop3h 15m
Deal found 9/6![Southwest logo]()
$478
This Southwest deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/161:35 pm -
2 stops9h 10m
Sun 10/187:40 pm -
1 stop3h 45m
Deal found 9/4![Southwest logo]()
$552
This Southwest deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:30 pm -
1 stop6h 25m
Wed 9/167:00 am -
1 stop5h 45m
Deal found 9/3![Southwest logo]()
$611
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am -
1 stop5h 25m
Sun 9/137:35 am -
1 stop5h 20m
Deal found 9/6![Southwest logo]()
$634
Last-minute flights from Spartanburg to KnoxvilleDiscover last-minute flight deals from Spartanburg to Knoxville. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Spartanburg to Knoxville. Data last updated September 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:56 am -
1 stop27h 36m
Sat 9/123:51 pm -
1 stop16h 44m
Deal found 9/2![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 pm -
1 stop13h 56m
Sat 9/193:51 pm -
1 stop16h 44m
Deal found 9/3![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 pm -
1 stop13h 56m
Thu 9/175:38 pm -
1 stop14h 57m
Deal found 9/3![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:08 pm -
1 stop13h 56m
Wed 9/3010:28 am -
1 stop22h 07m
Deal found 9/6![Multiple Airlines logo]()
$326
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:32 am -
1 stop7h 11m
Wed 9/3010:28 am -
1 stop22h 07m
Deal found 9/6![Multiple Airlines logo]()
$318
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:08 pm -
1 stop11h 57m
Mon 10/59:28 pm -
1 stop11h 07m
Deal found 9/3![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:08 pm -
1 stop11h 57m
Sat 10/109:36 pm -
1 stop22h 19m
Deal found 9/5![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:51 pm -
1 stop7h 30m
Sat 10/109:36 pm -
1 stop22h 19m
Deal found 9/6![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:32 am -
1 stop8h 18m
Wed 10/76:41 pm -
1 stop13h 56m
Deal found 9/5![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:59 pm -
2 stops27h 31m
Fri 10/239:28 pm -
1 stop21h 45m
Deal found 9/4![Multiple Airlines logo]()
$282
One-way flights from Spartanburg to KnoxvilleSearch for one-way flight options from Spartanburg to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Spartanburg to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:08 pm -
1 stop11h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:34 am -
1 stop6h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:34 am -
1 stop6h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:40 pm -
1 stop17h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:50 am -
3 stops31h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:08 pm -
1 stop13h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/211:45 am -
2 stops46h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$154
Find flight deals from Spartanburg to Knoxville
Keep the following information in mind while searching for Spartanburg to Knoxville flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Kiwi.com) |
One-way from | $123 (Kiwi.com) |
Popular in | June |
Cheapest in | April |
Cheapflights Fare Finder
Customize your flight search to find flights from Spartanburg to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Spartanburg to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Wed 12/2
9:34 am-4:24 pm
1 stop6h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$125
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Tue 10/6
9:40 pm-2:42 pm
1 stop17h 02m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Thu 12/3
8:37 pm-6:42 pm
1 stop22h 05m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$160
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Fri 12/4
1:30 pm-8:45 pm
1 stop7h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
Quickest round-trip
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Sat 12/5
6:40 am-12:00 pm
1 stop5h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Wed 11/4
6:40 am-12:20 pm
1 stop5h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Mon 11/30
8:54 am-3:42 pm
1 stop30h 48m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Sun 10/4
5:38 pm-10:35 am
1 stop16h 57m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$187
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Sat 10/3
7:55 am-5:50 pm
2 stops9h 55m
Knoxville McGhee Tyson
Mon 10/5
7:25 pm-10:50 pm
1 stop3h 25m
$358
CharlotteKnoxville
CLT Charlotte Douglas - TYS Knoxville McGhee Tyson
CLTTYS
Charlotte Douglas
Sat 11/21
12:25 pm-9:35 pm
1 stop9h 10m
Knoxville McGhee Tyson
Fri 11/27
7:25 pm-10:40 pm
1 stop3h 15m
$378
Showing 1-10 of 20 resultsSorted by cheapest first
Best time to book a flight from Spartanburg to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Spartanburg with our price prediction graph.
CLT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Spartanburg to Knoxville
SB1-TYS
CLT-TYS
What is the cheapest time of day to fly from SB1 to TYS?
Find hourly flight availability from Spartanburg to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 7, 2026.
It’s typically best to fly out from Spartanburg to Knoxville in the morning. Doing so could potentially save you 27% on the flight price compared to flying in the evening, which is usually more expensive.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 7, 2026.
Read reviews from past customers who have flown American Airlines from Spartanburg to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Entertainment
6.8
Overall
7.1
Comfort
7.2
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Boarding
7.5
Entertainment
6.8
Overall
7.1
Comfort
7.2
Food
6.4
Crew
7.9
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from Spartanburg to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Consider these flights traveling from Spartanburg to Knoxville.
Top airline flying from Spartanburg to Knoxville
Discover the top airline that operate flights from Spartanburg to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$487 | Average$555 | FlexibilityNo cancel fee | On-time71% |