$60+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
May 10 — May 171
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.
This Expedia deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:45 pm
ORD
- CLT
1 stop6h 03m
Multiple Airlines
Sat 4/117:09 pm
CLT
- ORD
Nonstop2h 30m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$132
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:30 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Fri 4/1010:43 pm
CLT
- ORD
Nonstop2h 21m
Frontier
Deal found 4/5![Frontier logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Thu 5/712:48 pm
CLT
- ORD
1 stop12h 08m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$134
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sat 5/25:51 pm
CLT
- ORD
1 stop16h 54m
Frontier
Deal found 4/6![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/712:45 pm
ORD
- CLT
1 stop6h 03m
Multiple Airlines
Thu 4/98:24 pm
CLT
- ORD
Nonstop2h 23m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$136
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Multiple Airlines
Thu 4/239:54 pm
CLT
- ORD
1 stop12h 42m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$137
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:15 pm
ORD
- CLT
1 stop12h 55m
Multiple Airlines
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$138
This Super.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Wed 4/299:54 pm
CLT
- ORD
1 stop12h 42m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$139
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:14 am
MDW
- CLT
1 stop6h 21m
Frontier
Sat 5/28:09 pm
CLT
- MDW
1 stop12h 32m
Frontier
Deal found 4/6![Frontier logo]()
$140
This Expedia deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:45 pm
ORD
- CLT
1 stop22h 28m
Frontier
Mon 5/115:58 pm
CLT
- ORD
1 stop30h 03m
Frontier
Deal found 4/5![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Multiple Airlines
Sat 4/252:59 pm
CLT
- ORD
1 stop10h 25m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$141
This Super.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
ORD
- CLT
Nonstop2h 17m
Frontier
Mon 4/205:17 pm
CLT
- ORD
Nonstop2h 33m
Frontier
Deal found 4/7![Frontier logo]()
$142
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 10, 2026.
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Sat 5/98:10 am
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 4/8![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/42:00 pm
ORD
- CLT
Nonstop2h 11m
United Airlines
Tue 5/128:05 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Deal found 4/9![United Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/301:27 pm
ORD
- GSP
1 stop26h 26m
Multiple Airlines
Mon 5/44:07 pm
GSP
- ORD
1 stop8h 51m
Multiple Airlines
Deal found 4/9![Multiple Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:35 pm
ORD
- GSP
1 stop4h 50m
Delta
Sat 9/53:42 pm
GSP
- ORD
1 stop5h 35m
Delta
Deal found 4/5![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:15 am
ORD
- CHS
Nonstop2h 16m
American Airlines
Mon 6/18:25 am
CHS
- ORD
Nonstop2h 33m
American Airlines
Deal found 4/9![American Airlines logo]()
$327
This Sun Country Air deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:06 pm
ORD
- CLT
1 stop14h 45m
Sun Country Air
Sun 5/38:00 am
CLT
- ORD
1 stop12h 06m
Sun Country Air
Deal found 4/6![Sun Country Air logo]()
$377
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:30 pm
MDW
- CLT
Nonstop2h 00m
Southwest
Tue 5/191:45 pm
CLT
- MDW
1 stop6h 45m
Southwest
Deal found 4/5![Southwest logo]()
$247
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/277:08 am
ORD
- GSP
Nonstop2h 06m
United Airlines
Tue 6/307:40 pm
GSP
- ORD
1 stop4h 46m
United Airlines
Deal found 4/9![United Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Tue 5/196:40 am
CLT
- MDW
2 stops9h 45m
Southwest
Deal found 4/9![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
ORD
- GSP
1 stop3h 55m
Delta
Mon 5/117:42 pm
GSP
- ORD
1 stop5h 17m
Delta
Deal found 4/5![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:50 am
ORD
- GSP
Nonstop1h 57m
United Airlines
Mon 5/47:35 pm
GSP
- ORD
1 stop5h 09m
United Airlines
Deal found 4/9![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/143:50 pm
MDW
- CLT
1 stop5h 50m
Southwest
Sun 5/178:50 pm
CLT
- MDW
1 stop4h 30m
Southwest
Deal found 4/9![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:07 am
ORD
- HHH
1 stop7h 26m
Delta
Tue 6/24:16 pm
HHH
- ORD
1 stop7h 20m
Delta
Deal found 4/5![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1711:00 am
ORD
- MYR
Nonstop2h 18m
United Airlines
Sat 5/233:08 pm
MYR
- ORD
Nonstop2h 34m
United Airlines
Deal found 4/9![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:50 am
MDW
- CLT
Nonstop2h 05m
Southwest
Sat 6/207:50 am
CLT
- MDW
Nonstop1h 55m
Southwest
Deal found 4/6![Southwest logo]()
$259
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:35 am
ORD
- GSP
1 stop7h 49m
Delta
Sun 7/55:44 am
GSP
- ORD
1 stop3h 54m
Delta
Deal found 4/8![Delta logo]()
$302
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:50 am
ORD
- GSP
Nonstop1h 57m
United Airlines
Sun 5/36:36 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/5![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:50 pm
MDW
- CLT
2 stops6h 55m
Southwest
Wed 5/137:20 pm
CLT
- MDW
1 stop3h 55m
Southwest
Deal found 4/7![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:00 am
ORD
- GSP
1 stop7h 17m
Delta
Sun 9/136:45 am
GSP
- ORD
1 stop4h 19m
Delta
Deal found 4/6![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:53 am
ORD
- MYR
Nonstop2h 19m
United Airlines
Tue 6/1610:00 am
MYR
- ORD
1 stop5h 48m
United Airlines
Deal found 4/9![United Airlines logo]()
$286
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Fri 5/158:30 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 4/9![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:00 am
ORD
- MYR
Nonstop2h 18m
United Airlines
Tue 5/53:14 pm
MYR
- ORD
Nonstop2h 32m
United Airlines
Deal found 4/5![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:50 am
ORD
- CLT
1 stop5h 36m
Delta
Fri 5/15:12 pm
CLT
- ORD
1 stop4h 28m
Delta
Deal found 4/9![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1011:25 am
MDW
- CLT
2 stops9h 40m
Southwest
Tue 6/167:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 4/7![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:50 am
ORD
- GSP
Nonstop1h 57m
United Airlines
Fri 5/156:36 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/9![United Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:10 pm
MDW
- MYR
1 stop5h 48m
Delta
Sat 5/234:54 pm
MYR
- MDW
1 stop5h 15m
Delta
Deal found 4/6![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:40 pm
ORD
- CHS
1 stop5h 10m
Southwest
Wed 6/37:40 am
CHS
- ORD
2 stops11h 45m
Southwest
Deal found 4/9![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:40 am
ORD
- GSP
Nonstop2h 03m
United Airlines
Sun 9/136:30 am
GSP
- ORD
Nonstop2h 07m
United Airlines
Deal found 4/6![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Mon 5/47:00 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 4/7![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/287:01 am
ORD
- CLT
1 stop4h 25m
Delta
Sun 7/56:59 am
CLT
- ORD
1 stop6h 37m
Delta
Deal found 4/6![Delta logo]()
$343
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated April 10, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated April 10, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/121:02 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Mon 4/139:40 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Deal found 4/6![Frontier logo]()
$132
This Super.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
ORD
- CLT
Nonstop2h 17m
Frontier
Mon 4/205:17 pm
CLT
- ORD
Nonstop2h 33m
Frontier
Deal found 4/7![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Multiple Airlines
Thu 4/2312:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$133
This Cheapflightsfares deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Thu 5/712:48 pm
CLT
- ORD
1 stop12h 08m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$134
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Multiple Airlines
Sat 4/252:59 pm
CLT
- ORD
1 stop10h 25m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$141
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:28 am
ORD
- CLT
2 stops21h 49m
Spirit Airlines
Thu 4/239:54 pm
CLT
- ORD
1 stop12h 42m
Spirit Airlines
Deal found 4/6![Spirit Airlines logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:15 pm
MDW
- CLT
2 stops16h 54m
Multiple Airlines
Sun 4/267:19 pm
CLT
- MDW
1 stop13h 45m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$172
This CheapOair deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sat 5/25:51 pm
CLT
- ORD
1 stop16h 54m
Frontier
Deal found 4/6![Frontier logo]()
$135
This Super.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Wed 4/299:54 pm
CLT
- ORD
1 stop12h 42m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$139
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:14 am
MDW
- CLT
1 stop6h 21m
Frontier
Sat 5/28:09 pm
CLT
- MDW
1 stop12h 32m
Frontier
Deal found 4/6![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:15 pm
ORD
- CLT
1 stop12h 55m
Multiple Airlines
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$138
This Expedia deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:45 pm
ORD
- CLT
1 stop22h 28m
Frontier
Mon 5/115:58 pm
CLT
- ORD
1 stop30h 03m
Frontier
Deal found 4/5![Frontier logo]()
$140
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 4/6![Frontier logo]()
$60
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:05 am
ORD
- CLT
1 stop7h 49m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$62
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 4/6![Frontier logo]()
$63
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:38 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 4/5![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:05 am
ORD
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 4/8![Spirit Airlines logo]()
$65
This Super.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:30 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Deal found 4/9![Frontier logo]()
$67
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:22 pm
ORD
- CLT
Nonstop2h 17m
Frontier
Deal found 4/6![Frontier logo]()
$68
This Cheapflightsfares deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:15 pm
ORD
- CLT
1 stop12h 55m
Spirit Airlines
Deal found 4/7![Spirit Airlines logo]()
$69
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:14 am
MDW
- CLT
1 stop6h 21m
Frontier
Deal found 4/6![Frontier logo]()
$70
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:16 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Deal found 4/6![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:52 pm
MDW
- CLT
1 stop18h 13m
Frontier
Deal found 4/6![Frontier logo]()
$75
This CheapOair deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:33 am
MDW
- CLT
1 stop28h 02m
Frontier
Deal found 4/7![Frontier logo]()
$76
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated April 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $132 (Super.com) |
One-way from | $60 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $365 |
Good round-trip deal | $134 or less |
Good one-way deal | $191 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 5/8
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Sat 5/9
8:10 am-9:10 am
Nonstop2h 00m
$237
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sun 5/17
7:30 pm-10:30 pm
Nonstop2h 00m
Charlotte Douglas
Tue 5/19
1:45 pm-7:30 pm
1 stop6h 45m
$247
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Thu 5/14
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Tue 5/19
6:40 am-3:25 pm
2 stops9h 45m
$252
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Mon 5/4
2:00 pm-5:11 pm
Nonstop2h 11m
Charlotte Douglas
Tue 5/12
8:05 am-9:23 am
Nonstop2h 18m
$257
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Thu 5/14
3:50 pm-10:40 pm
1 stop5h 50m
Charlotte Douglas
Sun 5/17
8:50 pm-12:20 am
1 stop4h 30m
$257
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 4/30
1:27 pm-4:53 pm
1 stop26h 26m
Greenville
Mon 5/4
4:07 pm-11:58 pm
1 stop8h 51m
$259
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sat 6/13
7:50 am-10:55 am
Nonstop2h 05m
Charlotte Douglas
Sat 6/20
7:50 am-8:45 am
Nonstop1h 55m
$259
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Wed 5/6
12:50 pm-8:45 pm
2 stops6h 55m
Charlotte Douglas
Wed 5/13
7:20 pm-10:15 pm
1 stop3h 55m
$262
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/27
7:08 am-10:14 am
Nonstop2h 06m
Greenville
Tue 6/30
7:40 pm-11:26 pm
1 stop4h 46m
$265
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 5/8
7:05 pm-10:00 pm
Nonstop1h 55m
Charlotte Douglas
Fri 5/15
8:30 pm-11:30 pm
1 stop4h 00m
$267
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CLT
MDW-CLT
MDW-MYR
ORD-MYR
ORD-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CLT
MDW-CLT
MDW-MYR
ORD-MYR
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $60). Flying from Illinois to South Carolina in February is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 10, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 21% on airfare.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on April 4, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 10, 2026.
The most flights from USIL to USSC are scheduled on a Thursday (22 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (15 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 10, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on April 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 6 airlines flying from Illinois to South Carolina
Discover the top 6 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$52 | Average$165 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$108 | Average$148 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$124 | Average$397 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$146 | Average$318 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$386 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$186 | Average$383 | FlexibilityNo cancel fee | On-time69% |