$70+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This Super.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Fri 5/14:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/27![Frontier logo]()
$154
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 am
ORD
- CLT
1 stop8h 06m
Multiple Airlines
Wed 5/2012:13 pm
CLT
- ORD
1 stop11h 33m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 6/11:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/27![Frontier logo]()
$159
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Mon 5/187:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/26![Frontier logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sat 5/161:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/25![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Sat 5/231:00 pm
CLT
- ORD
1 stop11h 13m
Frontier
Deal found 4/26![Frontier logo]()
$164
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:20 am
ORD
- CLT
1 stop7h 35m
Frontier
Wed 6/246:33 pm
CLT
- ORD
1 stop19h 10m
Frontier
Deal found 4/26![Frontier logo]()
$165
This Super.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:05 am
ORD
- CLT
1 stop27h 00m
Frontier
Fri 5/291:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/27![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Sat 5/161:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/25![Frontier logo]()
$167
This eDestinos deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/26![Frontier logo]()
$168
This Frontier deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/26![Frontier logo]()
$170
This Expedia deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:52 pm
MDW
- CLT
1 stop22h 51m
Frontier
Sun 5/177:58 pm
CLT
- MDW
1 stop20h 59m
Frontier
Deal found 4/29![Frontier logo]()
$201
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Tue 6/97:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 4/24![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 6/278:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 4/25![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:05 am
STL
- CLT
1 stop5h 22m
Delta
Sun 5/319:47 am
CLT
- STL
1 stop4h 23m
Delta
Deal found 4/27![Delta logo]()
$270
This Contour deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2711:20 am
ORD
- CLT
1 stop4h 40m
Contour
Wed 6/36:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 4/29![Contour logo]()
$285
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:10 am
ORD
- HHH
1 stop5h 00m
American Airlines
Tue 5/262:03 pm
HHH
- ORD
Nonstop2h 35m
American Airlines
Deal found 4/24![American Airlines logo]()
$436
This JetBlue deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/299:35 am
ORD
- SAV
1 stop7h 46m
JetBlue
Thu 7/210:49 am
SAV
- ORD
1 stop6h 27m
JetBlue
Deal found 4/28![JetBlue logo]()
$437
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:50 pm
ORD
- GSP
Nonstop2h 08m
United Airlines
Sun 5/176:36 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/24![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/202:35 pm
ORD
- GSP
1 stop6h 13m
Delta
Wed 6/243:35 pm
GSP
- ORD
1 stop7h 59m
Delta
Deal found 4/24![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3010:55 am
STL
- CLT
1 stop3h 15m
Southwest
Sun 5/3112:50 pm
CLT
- STL
Nonstop2h 05m
Southwest
Deal found 4/27![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:40 pm
ORD
- GSP
1 stop7h 08m
Delta
Sat 7/412:46 pm
GSP
- ORD
1 stop4h 44m
Delta
Deal found 4/25![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/272:30 pm
STL
- CLT
1 stop6h 10m
Southwest
Fri 5/298:20 am
CLT
- STL
2 stops8h 10m
Southwest
Deal found 4/29![Southwest logo]()
$288
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:35 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sun 7/56:15 am
CLT
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/27![United Airlines logo]()
$291
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:05 am
MDW
- CLT
1 stop4h 13m
Delta
Sat 7/116:00 am
CLT
- MDW
1 stop4h 08m
Delta
Deal found 4/27![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/231:13 pm
STL
- CLT
1 stop7h 16m
United Airlines
Sat 5/307:00 am
CLT
- STL
2 stops9h 46m
United Airlines
Deal found 4/29![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:22 am
MDW
- CLT
1 stop5h 28m
Delta
Sat 5/305:30 pm
CLT
- MDW
1 stop4h 39m
Delta
Deal found 4/28![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:40 pm
ORD
- GSP
1 stop6h 00m
Southwest
Thu 5/216:25 am
GSP
- ORD
1 stop7h 25m
Southwest
Deal found 4/28![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
STL
- CLT
2 stops7h 12m
United Airlines
Wed 6/248:05 am
CLT
- STL
1 stop5h 06m
United Airlines
Deal found 4/25![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/39:48 am
ORD
- CLT
1 stop5h 30m
Delta
Sat 7/118:05 am
CLT
- ORD
1 stop7h 20m
Delta
Deal found 4/29![Delta logo]()
$279
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:40 pm
MDW
- CLT
1 stop3h 35m
Southwest
Sat 7/111:00 pm
CLT
- MDW
2 stops9h 50m
Southwest
Deal found 4/27![Southwest logo]()
$309
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:50 pm
STL
- CLT
Nonstop1h 50m
Southwest
Thu 7/239:15 pm
CLT
- STL
1 stop3h 50m
Southwest
Deal found 4/26![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:35 am
ORD
- GSP
1 stop8h 47m
Delta
Thu 7/93:35 pm
GSP
- ORD
1 stop8h 01m
Delta
Deal found 4/24![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:40 am
ORD
- MYR
1 stop5h 33m
United Airlines
Tue 5/196:00 pm
MYR
- ORD
1 stop6h 37m
United Airlines
Deal found 4/28![United Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:20 pm
MDW
- CHS
Nonstop2h 05m
Southwest
Fri 6/195:55 pm
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 4/27![Southwest logo]()
$309
This JetBlue deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/19:35 am
ORD
- SAV
1 stop7h 46m
JetBlue
Tue 7/710:55 am
SAV
- ORD
1 stop7h 25m
JetBlue
Deal found 4/26![JetBlue logo]()
$498
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:01 am
ORD
- GSP
1 stop4h 05m
Delta
Sun 7/57:10 am
GSP
- ORD
1 stop4h 40m
Delta
Deal found 4/25![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
ORD
- CHS
Nonstop2h 23m
United Airlines
Tue 6/26:00 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 4/28![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Sun 5/317:00 am
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 4/25![Southwest logo]()
$311
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/210:35 am
ORD
- GSP
1 stop8h 47m
Delta
Sun 7/58:52 am
GSP
- ORD
1 stop4h 44m
Delta
Deal found 4/26![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:25 pm
ORD
- CHS
Nonstop2h 23m
United Airlines
Sat 7/256:00 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 4/27![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/303:10 pm
MDW
- CLT
1 stop5h 55m
Southwest
Mon 7/69:15 pm
CLT
- MDW
1 stop4h 00m
Southwest
Deal found 4/27![Southwest logo]()
$311
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated April 29, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Fri 5/14:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/27![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 6/11:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/27![Frontier logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/24![Frontier logo]()
$168
This Super.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/24![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sat 5/161:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/25![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/107:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Sat 5/161:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/25![Frontier logo]()
$167
This Priceline deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Sat 5/161:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/25![Frontier logo]()
$160
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:52 pm
MDW
- CLT
1 stop22h 51m
Frontier
Sun 5/177:58 pm
CLT
- MDW
1 stop20h 59m
Frontier
Deal found 4/28![Frontier logo]()
$212
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Sat 5/231:00 pm
CLT
- ORD
1 stop11h 13m
Frontier
Deal found 4/26![Frontier logo]()
$164
This Priceline deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:05 am
ORD
- CLT
1 stop8h 06m
Multiple Airlines
Wed 5/2012:13 pm
CLT
- ORD
1 stop11h 33m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$155
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:20 am
ORD
- CLT
1 stop7h 35m
Frontier
Wed 6/246:33 pm
CLT
- ORD
1 stop19h 10m
Frontier
Deal found 4/26![Frontier logo]()
$165
This Super.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:05 am
ORD
- CLT
1 stop27h 00m
Frontier
Fri 5/291:00 pm
CLT
- ORD
1 stop6h 44m
Frontier
Deal found 4/27![Frontier logo]()
$166
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:51 pm
STL
- CLT
1 stop11h 08m
Frontier
Deal found 4/29![Frontier logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:52 am
ORD
- CLT
1 stop27h 22m
Frontier
Deal found 4/28![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:05 am
ORD
- CLT
1 stop27h 00m
Frontier
Deal found 4/26![Frontier logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:52 am
ORD
- CLT
1 stop14h 48m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:05 am
ORD
- CLT
1 stop27h 00m
Frontier
Deal found 4/27![Frontier logo]()
$81
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:44 pm
ORD
- CLT
1 stop19h 21m
Frontier
Deal found 4/24![Frontier logo]()
$83
This Super.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 4/28![Frontier logo]()
$84
This Trip.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:05 am
ORD
- CLT
1 stop27h 00m
Frontier
Deal found 4/27![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:30 am
ORD
- CLT
1 stop7h 56m
Frontier
Deal found 4/26![Frontier logo]()
$89
This Frontier deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:51 pm
STL
- CLT
1 stop11h 08m
Frontier
Deal found 4/29![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:05 am
ORD
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 4/24![Spirit Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/307:52 pm
ORD
- MYR
1 stop14h 56m
Frontier
Deal found 4/28![Frontier logo]()
$92
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $155 (Priceline) |
One-way from | $70 (Frontier) |
Popular in | December |
Cheapest in | August |
Average price | $381 |
Good round-trip deal | $325 or less |
Good one-way deal | $177 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Tue 6/2
6:00 pm-8:55 pm
Nonstop1h 55m
Charlotte Douglas
Tue 6/9
7:05 pm-8:10 pm
Nonstop2h 05m
$259
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 6/20
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Sat 6/27
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 5/15
7:50 pm-10:58 pm
Nonstop2h 08m
Greenville
Sun 5/17
6:36 am-8:00 am
Nonstop2h 24m
$269
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sat 5/30
7:05 am-1:27 pm
1 stop5h 22m
Charlotte Douglas
Sun 5/31
9:47 am-1:10 pm
1 stop4h 23m
$270
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/20
2:35 pm-9:48 pm
1 stop6h 13m
Greenville
Wed 6/24
3:35 pm-10:34 pm
1 stop7h 59m
$275
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 7/3
1:40 pm-9:48 pm
1 stop7h 08m
Greenville
Sat 7/4
12:46 pm-4:30 pm
1 stop4h 44m
$275
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Fri 7/3
11:05 am-4:18 pm
1 stop4h 13m
Charlotte Douglas
Sat 7/11
6:00 am-9:08 am
1 stop4h 08m
$279
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Sun 5/24
9:22 am-3:50 pm
1 stop5h 28m
Charlotte Douglas
Sat 5/30
5:30 pm-9:09 pm
1 stop4h 39m
$279
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Fri 7/3
9:48 am-4:18 pm
1 stop5h 30m
Charlotte Douglas
Sat 7/11
8:05 am-2:25 pm
1 stop7h 20m
$279
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Sat 5/30
10:55 am-3:10 pm
1 stop3h 15m
Charlotte Douglas
Sun 5/31
12:50 pm-1:55 pm
Nonstop2h 05m
$281
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CLT
MDW-CLT
ORD-MYR
MDW-SAV
ORD-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CLT
MDW-CLT
ORD-MYR
MDW-SAV
How far ahead should I book a flight from Illinois to South Carolina?
To ensure you get the cheapest price possible for a flight from Illinois to South Carolina, you should look to book at least 42 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $101). Flying from Illinois to South Carolina in September is currently the most expensive (average of $741). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 12% on airfare.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on April 25, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 29, 2026.
The most flights from USIL to USSC are scheduled on a Wednesday (17 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 6 airlines flying from Illinois to South Carolina
Discover the top 6 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$52 | Average$171 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$108 | Average$156 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$146 | Average$328 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$383 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$190 | Average$388 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$202 | Average$403 | FlexibilityNo cancel fee | On-time71% |