$122+ Cheap flights from Illinois to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to South Carolina
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
1 stop26h 48m
Mon 12/146:12 pm -
2 stops21h 18m
Deal found 11/6![Multiple Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/149:00 am -
1 stop6h 57m
Mon 1/185:46 pm -
1 stop7h 11m
Deal found 11/4![American Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop4h 50m
Sat 12/125:39 pm -
1 stop6h 15m
Deal found 11/5![Delta logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:13 am -
2 stops33h 16m
Thu 12/1710:15 pm -
1 stop19h 44m
Deal found 11/5![Multiple Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:25 pm -
1 stop5h 40m
Sat 12/129:45 am -
2 stops8h 35m
Deal found 11/5![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:55 pm -
2 stops19h 19m
Wed 12/92:57 pm -
1 stop24h 03m
Deal found 11/4![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
Nonstop2h 33m
Tue 12/1512:15 pm -
Nonstop2h 42m
Deal found 11/4![United Airlines logo]()
$290
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:30 am -
Nonstop2h 33m
Wed 12/166:00 am -
Nonstop2h 37m
Deal found 11/4![United Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:25 pm -
Nonstop2h 05m
Mon 12/78:00 am -
Nonstop2h 15m
Deal found 11/4![Southwest logo]()
$295
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:42 am -
1 stop6h 18m
Sat 12/1212:10 pm -
1 stop7h 04m
Deal found 11/5![United Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:30 am -
2 stops26h 14m
Wed 12/92:57 pm -
1 stop24h 03m
Deal found 11/4![Multiple Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:56 am -
1 stop5h 38m
Tue 12/154:23 pm -
Nonstop2h 37m
Deal found 11/4![American Airlines logo]()
$300
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/611:15 am -
1 stop5h 56m
Tue 3/94:30 pm -
1 stop7h 00m
Deal found 11/7![Delta logo]()
$301
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/115:10 am -
2 stops9h 15m
Sat 12/129:45 am -
2 stops8h 35m
Deal found 11/4![Southwest logo]()
$331
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:30 am -
Nonstop2h 33m
Sun 12/137:56 pm -
1 stop4h 33m
Deal found 11/4![United Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/16:03 pm -
1 stop5h 18m
Mon 4/56:18 am -
1 stop5h 33m
Deal found 11/8![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/152:26 pm -
2 stops8h 33m
Tue 1/192:42 pm -
2 stops8h 02m
Deal found 11/4![United Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/1511:07 am -
1 stop6h 13m
Tue 1/1911:00 am -
1 stop6h 28m
Deal found 11/4![Delta logo]()
$336
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/251:25 pm -
Nonstop2h 05m
Wed 12/306:40 am -
Nonstop2h 15m
Deal found 11/5![Southwest logo]()
$337
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:45 am -
1 stop4h 27m
Sun 1/177:43 pm -
1 stop5h 36m
Deal found 11/7![American Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:30 am -
Nonstop2h 38m
Sun 1/247:51 pm -
1 stop4h 53m
Deal found 11/5![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/55:07 pm -
1 stop6h 10m
Mon 3/812:15 pm -
1 stop5h 07m
Deal found 11/7![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:45 pm -
1 stop5h 40m
Sat 12/53:55 pm -
1 stop4h 40m
Deal found 11/6![Southwest logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/227:54 am -
1 stop4h 11m
Mon 1/251:50 pm -
1 stop6h 29m
Deal found 11/4![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/158:33 am -
1 stop3h 53m
Tue 12/296:30 am -
1 stop4h 30m
Deal found 11/4![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:10 am -
1 stop4h 03m
Sun 12/207:41 pm -
1 stop4h 25m
Deal found 11/6![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/158:10 am -
1 stop6h 43m
Sun 1/1712:37 pm -
1 stop5h 47m
Deal found 11/6![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:18 pm -
1 stop5h 35m
Sun 1/175:38 am -
1 stop5h 46m
Deal found 11/5![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:55 am -
2 stops9h 10m
Sun 12/137:10 pm -
Nonstop2h 15m
Deal found 11/4![Southwest logo]()
$386
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:30 am -
Nonstop2h 33m
Sat 12/194:55 pm -
Nonstop2h 42m
Deal found 11/6![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:40 am -
2 stops7h 45m
Tue 12/83:25 pm -
2 stops8h 20m
Deal found 11/4![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:26 am -
1 stop5h 49m
Sat 12/268:36 pm -
1 stop4h 40m
Deal found 11/8![American Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:10 am -
1 stop6h 23m
Tue 12/156:00 am -
1 stop5h 26m
Deal found 11/7![Delta logo]()
$366
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:55 pm -
Nonstop2h 01m
Sat 11/2110:42 am -
Nonstop2h 06m
Deal found 11/3![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2412:50 pm -
1 stop4h 35m
Mon 12/287:15 pm -
1 stop5h 00m
Deal found 11/6![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:04 am -
1 stop4h 29m
Sat 12/511:26 am -
1 stop5h 51m
Deal found 11/6![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:05 am -
1 stop6h 39m
Sun 11/225:47 pm -
1 stop7h 12m
Deal found 11/3![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:55 pm -
Nonstop2h 03m
Thu 11/266:20 am -
Nonstop2h 16m
Deal found 11/7![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:30 am -
2 stops5h 30m
Sun 12/138:20 am -
1 stop6h 20m
Deal found 11/8![Southwest logo]()
$394
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/36:49 am -
1 stop5h 44m
Fri 12/112:18 pm -
1 stop5h 51m
Deal found 11/7![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:30 pm -
1 stop4h 31m
Sat 11/215:37 pm -
Nonstop2h 23m
Deal found 11/4![United Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1911:44 am -
1 stop4h 24m
Mon 11/235:47 pm -
1 stop7h 12m
Deal found 11/6![American Airlines logo]()
$444
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated November 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:13 am -
2 stops33h 16m
Thu 12/1710:15 pm -
1 stop19h 44m
Deal found 11/5![Multiple Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:30 am -
Nonstop2h 33m
Tue 12/1512:15 pm -
Nonstop2h 42m
Deal found 11/4![United Airlines logo]()
$290
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:56 am -
1 stop5h 38m
Tue 12/154:23 pm -
Nonstop2h 37m
Deal found 11/4![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:55 pm -
2 stops19h 19m
Wed 12/92:57 pm -
1 stop24h 03m
Deal found 11/4![Multiple Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:30 am -
Nonstop2h 33m
Wed 12/166:00 am -
Nonstop2h 37m
Deal found 11/4![United Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:25 pm -
Nonstop2h 05m
Mon 12/78:00 am -
Nonstop2h 15m
Deal found 11/4![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:30 am -
2 stops26h 14m
Wed 12/92:57 pm -
1 stop24h 03m
Deal found 11/4![Multiple Airlines logo]()
$297
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
1 stop4h 50m
Sat 12/125:39 pm -
1 stop6h 15m
Deal found 11/5![Delta logo]()
$273
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:25 pm -
1 stop5h 40m
Sat 12/129:45 am -
2 stops8h 35m
Deal found 11/5![Southwest logo]()
$284
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:42 am -
1 stop6h 18m
Sat 12/1212:10 pm -
1 stop7h 04m
Deal found 11/5![United Airlines logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
1 stop26h 48m
Mon 12/146:12 pm -
2 stops21h 18m
Deal found 11/6![Multiple Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/149:00 am -
1 stop6h 57m
Mon 1/185:46 pm -
1 stop7h 11m
Deal found 11/4![American Airlines logo]()
$273
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1112:05 pm -
Nonstop2h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$122
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:00 pm -
2 stops21h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$125
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/58:55 am -
Nonstop2h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:00 pm -
2 stops16h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:00 am -
2 stops14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$131
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:14 pm -
1 stop5h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:07 am -
2 stops32h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:32 pm -
2 stops13h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:30 am -
2 stops24h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$137
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:45 am -
1 stop5h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/41:18 pm -
2 stops17h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:07 am -
1 stop25h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$139
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $265 (Kiwi.com) |
One-way from | $122 (American Airlines) |
Popular in | December |
Cheapest in | January |
Average price | $461 |
Good round-trip deal | $278 or less |
Good one-way deal | $185 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Sat 1/23
10:25 am-1:46 pm
Nonstop2h 21m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$122
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Thu 1/28
12:06 pm-3:23 pm
Nonstop2h 17m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$122
ChicagoCharleston
MDW Chicago Midway - CHS Charleston
MDWCHS
Chicago Midway
Sat 1/23
5:14 pm-12:02 am
1 stop5h 48m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$132
ChicagoCharleston
MDW Chicago Midway - CHS Charleston
MDWCHS
Chicago Midway
Thu 1/28
8:45 am-3:20 pm
1 stop5h 35m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$137
ChicagoCharleston
MDW Chicago Midway - CHS Charleston
MDWCHS
Chicago Midway
Sat 1/23
7:55 am-5:55 pm
2 stops9h 00m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$142
ChicagoMyrtle Beach
MDW Chicago Midway - MYR Myrtle Beach Intl
MDWMYR
Chicago Midway
Thu 12/10
5:02 pm-11:44 am
2 stops17h 42m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$152
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Fri 12/18
10:30 am-2:00 pm
Nonstop2h 30m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
ChicagoCharleston
ORD Chicago O'Hare Intl - CHS Charleston
ORDCHS
Chicago O'Hare Intl
Thu 12/31
6:25 pm-10:13 pm
Nonstop2h 48m
Charleston
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$169
ChicagoGreenville
ORD Chicago O'Hare Intl - GSP Greenville
ORDGSP
Chicago O'Hare Intl
Wed 12/16
1:22 pm-8:34 pm
1 stop6h 12m
Greenville
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
ChicagoMyrtle Beach
ORD Chicago O'Hare Intl - MYR Myrtle Beach Intl
ORDMYR
Chicago O'Hare Intl
Tue 1/5
11:20 am-4:33 pm
1 stop4h 13m
Myrtle Beach Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$179
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CHS
MDW-CHS
ORD-GSP
MLI-CHS
MLI-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CHS
MDW-CHS
ORD-GSP
MLI-CHS
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, January is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $362). Flying from Illinois to South Carolina in March is currently the most expensive (average of $422). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 9% on airfare.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 9, 2026.
The most flights from USIL to USSC are scheduled on a Monday (22 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (20 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
Airfare is below average for this route at the moment.
Illinois to South Carolina flights typically cost between $370 and $574 in December.The cheapest round-trip price found within the last 5 days was $273 on American Airlines (Dec 14-Jan 18).
How far ahead should I book a flight from Illinois to South Carolina?
To ensure you get the cheapest price possible for a flight from Illinois to South Carolina, you should look to book at least 21 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on November 7, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 9, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 5 airlines flying from Illinois to South Carolina
Discover the top 5 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$117 | Average$160 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$152 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$209 | Average$420 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$390 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$244 | Average$421 | FlexibilityNo cancel fee | On-time63% |