$87+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/15. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Aug 13 — Aug 201
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 14, 2026.
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:53 am
STL
- CLT
Nonstop1h 57m
American Airlines
Sat 9/269:50 pm
CLT
- STL
Nonstop1h 52m
American Airlines
Deal found 7/10![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:45 pm
STL
- CLT
Nonstop1h 45m
Southwest
Mon 10/1210:40 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/10![Southwest logo]()
$192
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/3111:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/10![Southwest logo]()
$194
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/1011:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/13![Southwest logo]()
$197
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Tue 8/1810:00 pm
CLT
- STL
Nonstop1h 55m
American Airlines
Deal found 7/12![American Airlines logo]()
$200
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:05 am
ORD
- GSP
2 stops10h 28m
Multiple Airlines
Mon 8/3112:06 pm
GSP
- ORD
1 stop25h 44m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$203
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:45 pm
STL
- CLT
1 stop5h 05m
Southwest
Mon 8/1711:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/10![Southwest logo]()
$206
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am
STL
- CLT
1 stop6h 30m
Delta
Sat 9/265:02 pm
CLT
- STL
1 stop3h 56m
Delta
Deal found 7/10![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:05 am
ORD
- GSP
2 stops10h 34m
Multiple Airlines
Mon 8/3112:06 pm
GSP
- ORD
1 stop25h 44m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:05 am
ORD
- GSP
2 stops10h 28m
Multiple Airlines
Thu 8/278:37 am
GSP
- ORD
1 stop29h 13m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:05 am
ORD
- GSP
1 stop7h 02m
Multiple Airlines
Mon 8/174:57 pm
GSP
- ORD
1 stop20h 53m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:37 pm
ORD
- CHS
Nonstop2h 22m
American Airlines
Wed 8/267:50 pm
CHS
- ORD
Nonstop2h 44m
American Airlines
Deal found 7/13![American Airlines logo]()
$238
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 14, 2026.
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/3111:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/10![Southwest logo]()
$194
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/195:30 am
ORD
- CHS
1 stop4h 51m
Delta
Mon 9/285:25 am
CHS
- ORD
1 stop4h 10m
Delta
Deal found 7/13![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:50 am
ORD
- CHS
1 stop5h 10m
United Airlines
Thu 10/86:00 am
CHS
- ORD
1 stop4h 38m
United Airlines
Deal found 7/9![United Airlines logo]()
$265
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:45 pm
ORD
- CAE
Nonstop2h 10m
American Airlines
Sat 9/56:00 am
CAE
- ORD
Nonstop2h 30m
American Airlines
Deal found 7/9![American Airlines logo]()
$269
This Contour deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:30 am
ORD
- CLT
1 stop4h 30m
Contour
Wed 9/26:25 pm
CLT
- ORD
1 stop17h 25m
Contour
Deal found 7/12![Contour logo]()
$366
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/1011:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/11![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:59 pm
ORD
- CHS
1 stop7h 25m
Delta
Mon 8/1011:25 am
CHS
- ORD
1 stop6h 26m
Delta
Deal found 7/13![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:55 pm
ORD
- CAE
Nonstop2h 08m
United Airlines
Sun 9/136:25 am
CAE
- ORD
Nonstop2h 30m
United Airlines
Deal found 7/11![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:35 pm
STL
- CLT
Nonstop1h 45m
Southwest
Sun 10/2510:40 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/13![Southwest logo]()
$250
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:22 am
ORD
- CHS
1 stop5h 36m
Delta
Tue 8/181:01 pm
CHS
- ORD
1 stop6h 48m
Delta
Deal found 7/12![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:55 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Mon 8/175:43 pm
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 7/13![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Fri 8/2111:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/14![Southwest logo]()
$250
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:50 pm
ORD
- CHS
1 stop5h 54m
Delta
Mon 8/315:06 pm
CHS
- ORD
1 stop4h 49m
Delta
Deal found 7/13![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:59 am
ORD
- CLT
Nonstop2h 25m
United Airlines
Sat 9/266:00 am
CLT
- ORD
1 stop6h 48m
United Airlines
Deal found 7/10![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:24 am
MDW
- SAV
1 stop7h 06m
Delta
Tue 9/86:45 am
SAV
- MDW
1 stop4h 52m
Delta
Deal found 7/13![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:45 am
STL
- CLT
2 stops7h 15m
Southwest
Sun 10/410:40 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/11![Southwest logo]()
$262
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:45 pm
ORD
- GSP
1 stop5h 06m
American Airlines
Sat 7/256:00 pm
GSP
- ORD
1 stop5h 00m
American Airlines
Deal found 7/9![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:50 am
ORD
- CLT
Nonstop2h 18m
United Airlines
Tue 8/1810:25 am
CLT
- ORD
1 stop5h 05m
United Airlines
Deal found 7/13![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:48 am
MDW
- SAV
1 stop3h 46m
Delta
Tue 9/298:00 am
SAV
- MDW
1 stop4h 55m
Delta
Deal found 7/12![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:10 am
MDW
- SAV
2 stops8h 05m
Southwest
Wed 8/198:00 am
SAV
- MDW
2 stops8h 25m
Southwest
Deal found 7/13![Southwest logo]()
$267
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:25 am
ORD
- HHH
Nonstop2h 38m
United Airlines
Tue 8/182:58 pm
HHH
- ORD
Nonstop3h 17m
United Airlines
Deal found 7/12![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:39 pm
MDW
- SAV
1 stop4h 14m
Delta
Wed 8/126:35 am
SAV
- MDW
1 stop6h 16m
Delta
Deal found 7/14![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:35 pm
MDW
- CLT
2 stops5h 25m
Southwest
Wed 9/26:35 pm
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 7/12![Southwest logo]()
$274
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:45 am
ORD
- GSP
1 stop4h 34m
United Airlines
Mon 8/315:43 pm
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 7/10![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:55 pm
ORD
- SAV
1 stop5h 04m
Delta
Mon 11/165:35 pm
SAV
- ORD
1 stop4h 35m
Delta
Deal found 7/11![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:55 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Mon 8/1711:50 am
CLT
- MDW
2 stops9h 20m
Southwest
Deal found 7/11![Southwest logo]()
$274
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1311:23 am
ORD
- SAV
1 stop5h 09m
Delta
Tue 8/185:05 pm
SAV
- ORD
1 stop4h 50m
Delta
Deal found 7/12![Delta logo]()
$257
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:10 pm
ORD
- CHS
Nonstop2h 23m
United Airlines
Thu 10/156:50 pm
CHS
- ORD
Nonstop2h 39m
United Airlines
Deal found 7/9![United Airlines logo]()
$295
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:05 am
ORD
- SAV
1 stop6h 49m
Delta
Sat 9/192:55 pm
SAV
- ORD
1 stop7h 00m
Delta
Deal found 7/12![Delta logo]()
$257
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:05 am
MDW
- CLT
1 stop5h 20m
Southwest
Tue 9/158:30 am
CLT
- MDW
2 stops9h 20m
Southwest
Deal found 7/13![Southwest logo]()
$284
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated July 14, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated July 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:00 am
STL
- CLT
1 stop6h 50m
United Airlines
Tue 8/45:52 pm
CLT
- STL
1 stop6h 44m
United Airlines
Deal found 7/13![United Airlines logo]()
$212
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/1011:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/13![Southwest logo]()
$197
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/69:15 am
STL
- CLT
1 stop5h 57m
Delta
Mon 8/105:30 am
CLT
- STL
1 stop3h 38m
Delta
Deal found 7/13![Delta logo]()
$217
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Tue 8/1810:00 pm
CLT
- STL
Nonstop1h 55m
American Airlines
Deal found 7/12![American Airlines logo]()
$200
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:45 pm
STL
- CLT
1 stop5h 05m
Southwest
Mon 8/1711:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/9![Southwest logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:05 am
ORD
- GSP
1 stop7h 02m
Multiple Airlines
Mon 8/174:57 pm
GSP
- ORD
1 stop20h 53m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:37 pm
ORD
- CHS
Nonstop2h 22m
American Airlines
Wed 8/267:50 pm
CHS
- ORD
Nonstop2h 44m
American Airlines
Deal found 7/13![American Airlines logo]()
$238
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/242:45 pm
STL
- CLT
Nonstop1h 50m
Southwest
Mon 8/3111:50 am
CLT
- STL
Nonstop1h 55m
Southwest
Deal found 7/10![Southwest logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:05 am
ORD
- GSP
2 stops10h 28m
Multiple Airlines
Mon 8/315:34 pm
GSP
- ORD
1 stop20h 16m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:05 am
ORD
- GSP
2 stops10h 28m
Multiple Airlines
Thu 8/278:37 am
GSP
- ORD
1 stop29h 13m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$231
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/263:45 pm
STL
- CLT
1 stop4h 25m
Southwest
Sat 8/296:30 am
CLT
- STL
2 stops7h 45m
Southwest
Deal found 7/14![Southwest logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:05 am
ORD
- GSP
2 stops10h 34m
Multiple Airlines
Mon 8/3112:06 pm
GSP
- ORD
1 stop25h 44m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$230
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:52 pm
ORD
- MYR
1 stop13h 51m
Frontier
Deal found 7/9![Frontier logo]()
$87
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:45 pm
STL
- CLT
Nonstop1h 45m
Southwest
Deal found 7/9![Southwest logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:05 am
ORD
- SAV
1 stop8h 50m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$95
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:35 pm
STL
- CLT
Nonstop1h 45m
Southwest
Deal found 7/9![Southwest logo]()
$97
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:15 am
ORD
- MYR
Nonstop2h 19m
American Airlines
Deal found 7/11![American Airlines logo]()
$99
This American Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:53 pm
STL
- CLT
Nonstop1h 54m
American Airlines
Deal found 7/13![American Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:05 am
ORD
- GSP
1 stop7h 39m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$100
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:25 pm
ORD
- CHS
Nonstop2h 23m
United Airlines
Deal found 7/9![United Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:05 am
ORD
- GSP
1 stop31h 02m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:44 pm
ORD
- CHS
1 stop11h 54m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$104
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:45 am
STL
- CLT
1 stop5h 35m
Southwest
Deal found 7/10![Southwest logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:13 pm
ORD
- CHS
1 stop14h 25m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$107
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated July 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $189 (American Airlines) |
One-way from | $87 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $405 |
Good round-trip deal | $117 or less |
Good one-way deal | $98 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Mon 8/24
2:45 pm-5:35 pm
Nonstop1h 50m
Charlotte Douglas
Mon 8/31
11:50 am-12:45 pm
Nonstop1h 55m
$194
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 8/6
2:45 pm-5:35 pm
Nonstop1h 50m
Charlotte Douglas
Mon 8/10
11:50 am-12:45 pm
Nonstop1h 55m
$197
Quickest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 10/22
5:35 pm-8:20 pm
Nonstop1h 45m
Charlotte Douglas
Sun 10/25
10:40 am-11:35 am
Nonstop1h 55m
$250
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Thu 8/20
2:45 pm-5:35 pm
Nonstop1h 50m
Charlotte Douglas
Fri 8/21
11:50 am-12:45 pm
Nonstop1h 55m
$250
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Sat 9/19
5:30 am-11:21 am
1 stop4h 51m
Charleston
Mon 9/28
5:25 am-8:35 am
1 stop4h 10m
$257
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Thu 8/6
1:59 pm-10:24 pm
1 stop7h 25m
Charleston
Mon 8/10
11:25 am-4:51 pm
1 stop6h 26m
$257
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Thu 8/13
11:22 am-5:58 pm
1 stop5h 36m
Charleston
Tue 8/18
1:01 pm-6:49 pm
1 stop6h 48m
$257
ChicagoCharleston
ORD - CHS
ORDCHS
Chicago O'Hare Intl
Thu 8/27
1:50 pm-8:44 pm
1 stop5h 54m
Charleston
Mon 8/31
5:06 pm-8:55 pm
1 stop4h 49m
$257
ChicagoSavannah
MDW - SAV
MDWSAV
Chicago Midway
Tue 9/1
9:24 am-5:30 pm
1 stop7h 06m
Savannah/Hilton Head
Tue 9/8
6:45 am-10:37 am
1 stop4h 52m
$257
ChicagoSavannah
MDW - SAV
MDWSAV
Chicago Midway
Thu 9/24
10:48 am-3:34 pm
1 stop3h 46m
Savannah/Hilton Head
Tue 9/29
8:00 am-11:55 am
1 stop4h 55m
$257
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
STL-CLT
ORD-GSP
ORD-CHS
ORD-CAE
ORD-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
STL-CLT
ORD-GSP
ORD-CHS
ORD-CAE
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $101). Flying from Illinois to South Carolina in September is currently the most expensive (average of $741). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 14, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 6% on airfare.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 14, 2026.
The most flights from USIL to USSC are scheduled on a Monday (19 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (14 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
How far ahead should I book a flight from Illinois to South Carolina?
To ensure you get the cheapest price possible for a flight from Illinois to South Carolina, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on July 11, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 14, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Comfort
8.0
Overall
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentSarah,Aug 2024
MDW - AUS
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on July 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 5 airlines flying from Illinois to South Carolina
Discover the top 5 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$117 | Average$168 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$146 | Average$349 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$408 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$202 | Average$422 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$209 | Average$400 | FlexibilityNo cancel fee | On-time69% |