$77+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/19. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Jun 10 — Jun 171
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.
This Expedia deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:59 pm
ORD
- CLT
1 stop22h 54m
Frontier
Tue 6/2310:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Deal found 5/10![Frontier logo]()
$190
This Super.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Tue 7/215:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/10![Frontier logo]()
$196
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- CLT
1 stop23h 24m
Frontier
Wed 6/106:45 am
CLT
- STL
1 stop12h 33m
Frontier
Deal found 5/6![Frontier logo]()
$199
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:48 pm
ORD
- CLT
1 stop22h 37m
Frontier
Tue 7/76:41 pm
CLT
- ORD
1 stop18h 44m
Frontier
Deal found 5/6![Frontier logo]()
$202
This Orbitz deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:05 pm
ORD
- CLT
1 stop11h 34m
Frontier
Tue 7/145:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/7![Frontier logo]()
$204
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:20 am
ORD
- CLT
1 stop4h 40m
Contour
Sun 6/216:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/7![Contour logo]()
$209
This Frontier deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:21 pm
STL
- CLT
1 stop9h 54m
Frontier
Wed 9/21:12 pm
CLT
- STL
1 stop12h 02m
Frontier
Deal found 5/6![Frontier logo]()
$210
This Travelocity deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:46 pm
ORD
- CLT
1 stop17h 43m
Frontier
Mon 8/108:02 pm
CLT
- ORD
1 stop28h 03m
Frontier
Deal found 5/8![Frontier logo]()
$210
This Mytrip deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:20 am
ORD
- CLT
1 stop4h 40m
Contour
Wed 6/36:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/10![Contour logo]()
$212
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:19 pm
STL
- CLT
1 stop18h 46m
Frontier
Wed 6/106:45 am
CLT
- STL
1 stop12h 33m
Frontier
Deal found 5/6![Frontier logo]()
$213
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:19 pm
STL
- CLT
1 stop18h 53m
Frontier
Sat 5/308:55 am
CLT
- STL
1 stop9h 39m
Frontier
Deal found 5/7![Frontier logo]()
$214
This Trip.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:05 am
ORD
- CLT
1 stop26h 57m
Frontier
Sat 7/251:00 pm
CLT
- ORD
1 stop7h 00m
Frontier
Deal found 5/7![Frontier logo]()
$214
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 11, 2026.
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/311:35 am
STL
- CLT
2 stops8h 10m
Southwest
Wed 6/101:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 5/6![Southwest logo]()
$232
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:25 am
ORD
- CLT
Nonstop2h 21m
United Airlines
Tue 6/238:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 5/7![United Airlines logo]()
$259
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:29 am
ORD
- GSP
1 stop6h 38m
American Airlines
Tue 6/307:20 am
GSP
- ORD
Nonstop2h 26m
American Airlines
Deal found 5/10![American Airlines logo]()
$279
This Contour deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Contour is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1611:20 am
ORD
- CLT
1 stop4h 40m
Contour
Mon 7/206:05 pm
CLT
- ORD
1 stop25h 00m
Contour
Deal found 5/5![Contour logo]()
$285
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:22 pm
ORD
- GSP
1 stop4h 37m
Delta
Sun 7/56:45 am
GSP
- ORD
1 stop6h 51m
Delta
Deal found 5/10![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/291:55 pm
ORD
- GSP
Nonstop2h 05m
United Airlines
Mon 6/15:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Deal found 5/9![United Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:50 pm
MDW
- SAV
Nonstop2h 05m
Southwest
Tue 6/96:35 pm
SAV
- MDW
Nonstop2h 15m
Southwest
Deal found 5/8![Southwest logo]()
$271
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Sun 6/286:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 5/10![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 pm
MDW
- CHS
Nonstop2h 05m
Southwest
Tue 6/163:00 pm
CHS
- MDW
2 stops6h 10m
Southwest
Deal found 5/6![Southwest logo]()
$272
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
MDW
- CHS
1 stop4h 54m
Delta
Sat 8/84:56 pm
CHS
- MDW
1 stop6h 40m
Delta
Deal found 5/10![Delta logo]()
$311
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:15 am
ORD
- GSP
1 stop5h 11m
American Airlines
Sun 6/287:20 am
GSP
- ORD
Nonstop2h 26m
American Airlines
Deal found 5/10![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:20 pm
ORD
- CLT
Nonstop2h 16m
United Airlines
Sat 8/156:00 am
CLT
- ORD
1 stop4h 38m
United Airlines
Deal found 5/10![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:45 pm
MDW
- MYR
Nonstop2h 00m
Southwest
Sat 7/45:35 pm
MYR
- MDW
1 stop4h 05m
Southwest
Deal found 5/7![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:05 am
MDW
- CHS
1 stop4h 49m
Delta
Sat 8/86:55 am
CHS
- MDW
1 stop6h 44m
Delta
Deal found 5/7![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:10 pm
ORD
- GSP
Nonstop2h 07m
United Airlines
Fri 7/37:40 pm
GSP
- ORD
1 stop4h 51m
United Airlines
Deal found 5/8![United Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:00 am
ORD
- CHS
1 stop4h 29m
American Airlines
Sun 6/218:04 pm
CHS
- ORD
Nonstop2h 41m
American Airlines
Deal found 5/5![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/612:55 pm
MDW
- SAV
Nonstop2h 10m
Southwest
Wed 6/106:35 pm
SAV
- MDW
Nonstop2h 15m
Southwest
Deal found 5/9![Southwest logo]()
$280
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:56 am
MDW
- CHS
1 stop3h 53m
Delta
Wed 8/121:01 pm
CHS
- MDW
1 stop4h 14m
Delta
Deal found 5/7![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:30 am
ORD
- GSP
1 stop6h 50m
United Airlines
Sat 6/66:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 5/9![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:30 am
MDW
- CHS
2 stops7h 55m
Southwest
Tue 6/91:50 pm
CHS
- MDW
1 stop6h 15m
Southwest
Deal found 5/5![Southwest logo]()
$286
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:42 pm
ORD
- GSP
1 stop5h 33m
American Airlines
Mon 5/257:32 pm
GSP
- ORD
1 stop5h 27m
American Airlines
Deal found 5/10![American Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:05 am
MDW
- SAV
1 stop4h 35m
Delta
Mon 8/105:35 am
SAV
- MDW
1 stop5h 24m
Delta
Deal found 5/9![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:55 pm
ORD
- SAV
Nonstop2h 30m
United Airlines
Mon 6/812:06 pm
SAV
- ORD
1 stop5h 56m
United Airlines
Deal found 5/8![United Airlines logo]()
$281
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:40 am
STL
- CLT
2 stops7h 55m
Southwest
Mon 6/294:00 pm
CLT
- STL
2 stops7h 50m
Southwest
Deal found 5/6![Southwest logo]()
$290
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:08 am
ORD
- SAV
1 stop5h 40m
Delta
Sat 6/207:00 am
SAV
- ORD
1 stop4h 13m
Delta
Deal found 5/10![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/256:25 pm
ORD
- CHS
Nonstop2h 23m
United Airlines
Tue 7/283:08 pm
CHS
- ORD
Nonstop2h 46m
United Airlines
Deal found 5/10![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/314:40 pm
STL
- CLT
1 stop4h 50m
Southwest
Wed 6/37:35 am
CLT
- STL
1 stop4h 55m
Southwest
Deal found 5/7![Southwest logo]()
$293
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:06 pm
ORD
- GSP
1 stop4h 37m
Delta
Mon 6/85:16 pm
GSP
- ORD
1 stop4h 16m
Delta
Deal found 5/7![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Thu 6/118:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 5/6![United Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/1312:50 pm
STL
- CLT
2 stops6h 55m
Southwest
Sun 6/149:20 pm
CLT
- STL
1 stop3h 35m
Southwest
Deal found 5/6![Southwest logo]()
$298
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated May 11, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated May 11, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:19 pm
STL
- CLT
1 stop18h 53m
Frontier
Sat 5/308:55 am
CLT
- STL
1 stop9h 39m
Frontier
Deal found 5/7![Frontier logo]()
$214
This Mytrip deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:20 am
ORD
- CLT
1 stop4h 40m
Contour
Wed 6/36:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/10![Contour logo]()
$212
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:19 pm
STL
- CLT
1 stop18h 46m
Frontier
Wed 6/106:45 am
CLT
- STL
1 stop12h 33m
Frontier
Deal found 5/6![Frontier logo]()
$213
This Trip.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:11 pm
ORD
- CLT
1 stop17h 54m
Frontier
Sun 6/75:58 pm
CLT
- ORD
1 stop30h 03m
Frontier
Deal found 5/10![Frontier logo]()
$217
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- CLT
1 stop23h 24m
Frontier
Wed 6/106:45 am
CLT
- STL
1 stop12h 33m
Frontier
Deal found 5/6![Frontier logo]()
$199
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:20 am
ORD
- CLT
1 stop4h 40m
Contour
Thu 6/116:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/7![Contour logo]()
$210
This Expedia deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Tue 6/910:01 am
CLT
- ORD
1 stop15h 47m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$216
This Expedia deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:59 pm
ORD
- CLT
1 stop22h 54m
Frontier
Tue 6/2310:01 am
CLT
- ORD
1 stop15h 47m
Frontier
Deal found 5/10![Frontier logo]()
$190
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:13 pm
STL
- CLT
Nonstop2h 02m
American Airlines
Wed 6/247:35 am
CLT
- STL
Nonstop1h 57m
American Airlines
Deal found 5/6![American Airlines logo]()
$217
This Mytrip deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:20 am
ORD
- CLT
1 stop4h 40m
Contour
Sun 6/216:05 pm
CLT
- ORD
1 stop17h 35m
Contour
Deal found 5/7![Contour logo]()
$209
This Super.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Tue 7/215:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 5/10![Frontier logo]()
$196
This Mytrip deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/309:48 pm
ORD
- CLT
1 stop22h 37m
Frontier
Tue 7/76:41 pm
CLT
- ORD
1 stop18h 44m
Frontier
Deal found 5/6![Frontier logo]()
$202
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:55 am
ORD
- SAV
1 stop6h 56m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:05 am
ORD
- SAV
1 stop6h 46m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:05 am
ORD
- GSP
1 stop22h 52m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:05 am
ORD
- SAV
1 stop6h 46m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:05 am
ORD
- SAV
1 stop6h 46m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:05 am
ORD
- GSP
1 stop22h 52m
Multiple Airlines
Deal found 5/8![Multiple Airlines logo]()
$99
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2611:20 am
ORD
- CLT
1 stop4h 40m
Contour
Deal found 5/10![Contour logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:11 pm
ORD
- CHS
1 stop15h 47m
Multiple Airlines
Deal found 5/7![Multiple Airlines logo]()
$100
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- CLT
1 stop18h 53m
Frontier
Deal found 5/9![Frontier logo]()
$100
This Booking.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2911:20 am
ORD
- CLT
1 stop4h 40m
Contour
Deal found 5/10![Contour logo]()
$100
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:46 pm
ORD
- CLT
1 stop17h 43m
Frontier
Deal found 5/8![Frontier logo]()
$101
This Booking.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:20 am
ORD
- CLT
1 stop4h 40m
Contour
Deal found 5/6![Contour logo]()
$103
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated May 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Expedia) |
One-way from | $77 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $383 |
Good round-trip deal | $191 or less |
Good one-way deal | $172 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 6/3
11:35 am-8:45 pm
2 stops8h 10m
Charlotte Douglas
Wed 6/10
1:25 pm-2:25 pm
Nonstop2h 00m
$232
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 6/20
10:25 am-1:46 pm
Nonstop2h 21m
Charlotte Douglas
Tue 6/23
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 5/29
1:55 pm-5:00 pm
Nonstop2h 05m
Greenville
Mon 6/1
5:43 pm-7:00 pm
Nonstop2h 17m
$262
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 6/25
6:55 am-9:55 am
Nonstop2h 00m
Greenville
Sun 6/28
6:10 am-7:30 am
Nonstop2h 20m
$269
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 8/11
6:20 pm-9:36 pm
Nonstop2h 16m
Charlotte Douglas
Sat 8/15
6:00 am-9:38 am
1 stop4h 38m
$269
Quickest round-trip
ChicagoSavannah
MDW - SAV
MDWSAV
Chicago Midway
Sat 6/6
5:50 pm-8:55 pm
Nonstop2h 05m
Savannah/Hilton Head
Tue 6/9
6:35 pm-7:50 pm
Nonstop2h 15m
$271
ChicagoCharleston
MDW - CHS
MDWCHS
Chicago Midway
Wed 6/3
6:00 pm-9:05 pm
Nonstop2h 05m
Charleston
Tue 6/16
3:00 pm-8:10 pm
2 stops6h 10m
$272
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Tue 6/30
6:10 pm-9:17 pm
Nonstop2h 07m
Greenville
Fri 7/3
7:40 pm-11:31 pm
1 stop4h 51m
$272
ChicagoMyrtle Beach
MDW - MYR
MDWMYR
Chicago Midway
Tue 6/30
6:45 pm-9:45 pm
Nonstop2h 00m
Myrtle Beach Intl
Sat 7/4
5:35 pm-8:40 pm
1 stop4h 05m
$276
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 6/27
6:29 am-2:07 pm
1 stop6h 38m
Greenville
Tue 6/30
7:20 am-8:46 am
Nonstop2h 26m
$279
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CLT
STL-CLT
MDW-MYR
ORD-MYR
ORD-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CLT
STL-CLT
MDW-MYR
ORD-MYR
How far ahead should I book a flight from Illinois to South Carolina?
To ensure you get the cheapest price possible for a flight from Illinois to South Carolina, you should look to book at least 42 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $101). Flying from Illinois to South Carolina in September is currently the most expensive (average of $741). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 11, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 12% on airfare.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on May 2, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 11, 2026.
The most flights from USIL to USSC are scheduled on a Friday (23 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (18 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 11, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on May 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 6 airlines flying from Illinois to South Carolina
Discover the top 6 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$52 | Average$170 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$108 | Average$168 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$146 | Average$321 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$385 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$197 | Average$388 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$202 | Average$405 | FlexibilityNo cancel fee | On-time71% |