$99+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/1. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:54 am
STL
- CLT
Nonstop1h 55m
American Airlines
Wed 8/269:45 pm
CLT
- STL
Nonstop1h 55m
American Airlines
Deal found 6/9![American Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:53 am
STL
- CLT
Nonstop1h 57m
American Airlines
Tue 9/229:50 pm
CLT
- STL
Nonstop1h 52m
American Airlines
Deal found 6/8![American Airlines logo]()
$193
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 am
STL
- CLT
1 stop7h 18m
United Airlines
Wed 8/268:05 am
CLT
- STL
1 stop4h 57m
United Airlines
Deal found 6/8![United Airlines logo]()
$209
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:15 am
STL
- CLT
2 stops9h 55m
Southwest
Wed 8/268:05 am
CLT
- STL
1 stop4h 15m
Southwest
Deal found 6/9![Southwest logo]()
$214
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:30 am
STL
- CLT
Nonstop1h 59m
American Airlines
Wed 7/157:37 am
CLT
- STL
Nonstop1h 56m
American Airlines
Deal found 6/9![American Airlines logo]()
$217
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:45 am
STL
- CLT
2 stops7h 15m
Southwest
Tue 9/291:30 pm
CLT
- STL
2 stops9h 10m
Southwest
Deal found 6/9![Southwest logo]()
$219
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:45 am
STL
- CLT
2 stops9h 40m
Southwest
Tue 9/221:30 pm
CLT
- STL
2 stops9h 10m
Southwest
Deal found 6/8![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:10 pm
STL
- CLT
1 stop5h 55m
Southwest
Tue 7/71:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 6/5![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:30 am
STL
- CLT
1 stop4h 25m
Southwest
Sat 9/53:25 pm
CLT
- STL
1 stop5h 05m
Southwest
Deal found 6/7![Southwest logo]()
$229
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:25 am
STL
- CLT
2 stops8h 25m
Southwest
Tue 7/141:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 6/5![Southwest logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:55 am
ORD
- GSP
1 stop23h 02m
Multiple Airlines
Fri 8/286:41 pm
GSP
- ORD
1 stop18h 44m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:05 am
ORD
- GSP
1 stop10h 51m
Multiple Airlines
Sun 7/128:37 am
GSP
- ORD
1 stop28h 38m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$239
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:00 pm
STL
- CLT
1 stop4h 10m
Southwest
Wed 7/87:05 pm
CLT
- STL
1 stop4h 25m
Southwest
Deal found 6/9![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:29 am
ORD
- CLT
Nonstop2h 14m
United Airlines
Wed 7/158:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/5![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:55 pm
ORD
- MYR
1 stop4h 40m
Delta
Mon 10/2611:10 am
MYR
- ORD
1 stop6h 23m
Delta
Deal found 6/9![Delta logo]()
$279
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:45 pm
ORD
- CLT
Nonstop2h 14m
American Airlines
Tue 7/72:35 pm
CLT
- ORD
Nonstop2h 21m
American Airlines
Deal found 6/9![American Airlines logo]()
$300
This JetBlue deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:40 am
ORD
- CHS
1 stop8h 39m
JetBlue
Mon 7/276:40 pm
CHS
- ORD
1 stop6h 04m
JetBlue
Deal found 6/9![JetBlue logo]()
$408
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:59 am
ORD
- CAE
Nonstop2h 13m
United Airlines
Mon 10/56:15 am
CAE
- ORD
Nonstop2h 33m
United Airlines
Deal found 6/9![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:15 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Tue 7/77:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 6/7![Southwest logo]()
$269
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:30 am
ORD
- GSP
1 stop5h 48m
Delta
Sun 7/57:10 am
GSP
- ORD
1 stop4h 40m
Delta
Deal found 6/9![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/85:55 pm
ORD
- CAE
Nonstop2h 21m
United Airlines
Wed 7/156:25 am
CAE
- ORD
Nonstop2h 27m
United Airlines
Deal found 6/9![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:40 am
MDW
- CLT
1 stop4h 05m
Southwest
Sat 8/157:55 am
CLT
- MDW
Nonstop1h 55m
Southwest
Deal found 6/7![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:46 pm
MDW
- CLT
1 stop6h 39m
Delta
Tue 9/111:50 am
CLT
- MDW
1 stop4h 54m
Delta
Deal found 6/8![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Wed 7/85:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/9![United Airlines logo]()
$269
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/247:05 pm
STL
- CLT
1 stop3h 15m
Southwest
Wed 7/291:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 6/6![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:45 am
ORD
- HHH
Nonstop2h 36m
United Airlines
Tue 7/143:05 pm
HHH
- ORD
Nonstop2h 46m
United Airlines
Deal found 6/9![United Airlines logo]()
$269
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/31:40 pm
ORD
- GSP
1 stop7h 08m
Delta
Thu 7/97:10 am
GSP
- ORD
1 stop4h 27m
Delta
Deal found 6/6![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/263:40 pm
STL
- CLT
Nonstop1h 50m
Southwest
Sat 7/48:00 am
CLT
- STL
1 stop9h 05m
Southwest
Deal found 6/5![Southwest logo]()
$296
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:00 am
ORD
- GSP
1 stop3h 51m
Delta
Sun 8/97:15 am
GSP
- ORD
1 stop6h 53m
Delta
Deal found 6/9![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:50 am
ORD
- CLT
Nonstop2h 18m
United Airlines
Sat 9/53:30 pm
CLT
- ORD
Nonstop2h 16m
United Airlines
Deal found 6/8![United Airlines logo]()
$271
This JetBlue deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/189:41 am
ORD
- SAV
1 stop7h 41m
JetBlue
Wed 7/2210:56 am
SAV
- ORD
1 stop7h 38m
JetBlue
Deal found 6/8![JetBlue logo]()
$423
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:22 pm
ORD
- CAE
1 stop4h 24m
Delta
Sun 7/55:35 am
CAE
- ORD
1 stop5h 38m
Delta
Deal found 6/6![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:40 am
STL
- CLT
1 stop4h 15m
Southwest
Mon 8/37:05 pm
CLT
- STL
1 stop4h 50m
Southwest
Deal found 6/6![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:55 am
ORD
- GSP
Nonstop2h 00m
United Airlines
Tue 7/75:43 pm
GSP
- ORD
Nonstop2h 17m
United Airlines
Deal found 6/8![United Airlines logo]()
$277
This KAYAK deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/128:00 am
ORD
- GSP
Nonstop2h 01m
American Airlines
Fri 7/177:20 pm
GSP
- ORD
Nonstop2h 31m
American Airlines
Deal found 6/9![American Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:30 am
ORD
- CAE
1 stop4h 39m
Delta
Sat 9/511:55 am
CAE
- ORD
1 stop5h 56m
Delta
Deal found 6/9![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:40 am
ORD
- SAV
1 stop5h 03m
United Airlines
Wed 7/1512:05 pm
SAV
- ORD
1 stop5h 57m
United Airlines
Deal found 6/9![United Airlines logo]()
$277
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/115:50 pm
MDW
- CLT
Nonstop2h 00m
Southwest
Mon 7/139:15 pm
CLT
- MDW
1 stop3h 55m
Southwest
Deal found 6/8![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:30 am
ORD
- CAE
1 stop4h 44m
Delta
Fri 7/247:39 pm
CAE
- ORD
1 stop5h 14m
Delta
Deal found 6/5![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:17 pm
ORD
- GSP
Nonstop2h 09m
United Airlines
Sun 7/126:10 am
GSP
- ORD
Nonstop2h 20m
United Airlines
Deal found 6/7![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:10 pm
MDW
- CLT
Nonstop2h 00m
Southwest
Thu 8/136:30 pm
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 6/9![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:35 am
ORD
- CAE
1 stop5h 24m
Delta
Sun 8/25:35 am
CAE
- ORD
1 stop4h 00m
Delta
Deal found 6/7![Delta logo]()
$299
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated June 10, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Wed 7/85:57 pm
CLT
- ORD
1 stop7h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:30 am
STL
- CLT
Nonstop1h 59m
American Airlines
Wed 7/157:37 am
CLT
- STL
Nonstop1h 56m
American Airlines
Deal found 6/9![American Airlines logo]()
$217
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:00 pm
STL
- CLT
1 stop4h 10m
Southwest
Wed 7/81:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 6/9![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/14:00 pm
STL
- CLT
1 stop4h 10m
Southwest
Tue 7/710:40 am
CLT
- STL
2 stops8h 45m
Southwest
Deal found 6/5![Southwest logo]()
$242
This Booking.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:52 am
ORD
- CLT
1 stop27h 22m
Frontier
Sun 7/510:59 pm
CLT
- ORD
1 stop11h 12m
Frontier
Deal found 6/5![Frontier logo]()
$252
This Super.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:29 pm
ORD
- CLT
1 stop18h 08m
Frontier
Mon 7/65:57 pm
CLT
- ORD
1 stop7h 52m
Frontier
Deal found 6/7![Frontier logo]()
$256
This Expedia deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:20 am
ORD
- CLT
1 stop4h 40m
Multiple Airlines
Tue 7/75:57 pm
CLT
- ORD
1 stop7h 52m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$250
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:25 am
STL
- CLT
2 stops8h 25m
Southwest
Tue 7/141:25 pm
CLT
- STL
Nonstop2h 00m
Southwest
Deal found 6/5![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- CLT
1 stop6h 31m
Delta
Wed 7/155:30 am
CLT
- STL
1 stop3h 49m
Delta
Deal found 6/9![Delta logo]()
$237
This CheapOair deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:09 pm
STL
- CLT
1 stop23h 49m
Frontier
Wed 7/810:04 pm
CLT
- STL
1 stop22h 19m
Frontier
Deal found 6/8![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:05 am
ORD
- GSP
1 stop10h 51m
Multiple Airlines
Sun 7/128:37 am
GSP
- ORD
1 stop28h 38m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$239
This CheapOair deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/254:09 pm
STL
- CLT
1 stop18h 20m
Frontier
Wed 7/2912:24 pm
CLT
- STL
1 stop12h 35m
Frontier
Deal found 6/9![Frontier logo]()
$254
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:05 am
ORD
- CLT
1 stop12h 02m
Frontier
Deal found 6/5![Frontier logo]()
$99
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:35 pm
MDW
- CLT
2 stops5h 25m
Southwest
Deal found 6/7![Southwest logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:05 am
ORD
- CLT
1 stop12h 08m
Frontier
Deal found 6/9![Frontier logo]()
$102
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:10 pm
ORD
- CHS
Nonstop2h 24m
United Airlines
Deal found 6/9![United Airlines logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:55 am
ORD
- CLT
1 stop27h 10m
Frontier
Deal found 6/8![Frontier logo]()
$104
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:25 am
MDW
- CLT
Nonstop1h 55m
Southwest
Deal found 6/8![Southwest logo]()
$105
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:45 pm
STL
- CLT
1 stop4h 25m
Southwest
Deal found 6/7![Southwest logo]()
$105
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:50 am
ORD
- CLT
Nonstop2h 18m
United Airlines
Deal found 6/9![United Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:55 am
ORD
- SAV
1 stop9h 00m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$105
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:27 am
ORD
- MYR
Nonstop2h 26m
United Airlines
Deal found 6/9![United Airlines logo]()
$107
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/182:40 pm
MDW
- MYR
Nonstop2h 00m
Southwest
Deal found 6/10![Southwest logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:30 pm
ORD
- CHS
1 stop14h 08m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$107
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $189 (American Airlines) |
One-way from | $99 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $395 |
Good round-trip deal | $269 or less |
Good one-way deal | $161 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharlotte
STL - CLT
STLCLT
Lambert-St Louis
Wed 7/1
4:00 pm-9:10 pm
1 stop4h 10m
Charlotte Douglas
Wed 7/8
7:05 pm-10:30 pm
1 stop4h 25m
$237
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 7/11
6:29 am-9:43 am
Nonstop2h 14m
Charlotte Douglas
Wed 7/15
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Thu 10/1
5:59 am-9:12 am
Nonstop2h 13m
Columbia Metropolitan
Mon 10/5
6:15 am-7:48 am
Nonstop2h 33m
$269
Quickest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Wed 7/1
6:15 pm-9:10 pm
Nonstop1h 55m
Charlotte Douglas
Tue 7/7
7:05 pm-8:10 pm
Nonstop2h 05m
$269
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Wed 7/8
5:55 pm-9:16 pm
Nonstop2h 21m
Columbia Metropolitan
Wed 7/15
6:25 am-7:52 am
Nonstop2h 27m
$269
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 7/1
6:55 am-9:55 am
Nonstop2h 00m
Greenville
Wed 7/8
5:43 pm-7:00 pm
Nonstop2h 17m
$269
ChicagoHilton Head Island
ORD - HHH
ORDHHH
Chicago O'Hare Intl
Tue 7/7
10:45 am-2:21 pm
Nonstop2h 36m
Hilton Head Island
Tue 7/14
3:05 pm-4:51 pm
Nonstop2h 46m
$269
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 9/1
6:50 am-10:08 am
Nonstop2h 18m
Charlotte Douglas
Sat 9/5
3:30 pm-4:46 pm
Nonstop2h 16m
$271
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Wed 7/1
6:55 am-9:55 am
Nonstop2h 00m
Greenville
Tue 7/7
5:43 pm-7:00 pm
Nonstop2h 17m
$277
ChicagoSavannah
ORD - SAV
ORDSAV
Chicago O'Hare Intl
Wed 7/8
8:40 am-2:43 pm
1 stop5h 03m
Savannah/Hilton Head
Wed 7/15
12:05 pm-5:02 pm
1 stop5h 57m
$277
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CHS
STL-CLT
ORD-SAV
ORD-CLT
ORD-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CHS
STL-CLT
ORD-SAV
ORD-CLT
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $101). Flying from Illinois to South Carolina in September is currently the most expensive (average of $766). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 10, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 8% on airfare.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 10, 2026.
The most flights from USIL to USSC are scheduled on a Monday (26 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (15 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
How far ahead should I book a flight from Illinois to South Carolina?
To ensure you get the cheapest price possible for a flight from Illinois to South Carolina, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on June 8, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 10, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
7.9
Crew
8.6
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on June 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 5 airlines flying from Illinois to South Carolina
Discover the top 5 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$108 | Average$168 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$146 | Average$332 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$392 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$202 | Average$411 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$205 | Average$401 | FlexibilityNo cancel fee | On-time69% |