$58+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
Apr 2 — Apr 91
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to South Carolina
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 3, 2026.
This Super.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Thu 4/234:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 2/26![Frontier logo]()
$96
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:11 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 3/2![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 2/28![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:01 pm
ORD
- CLT
1 stop4h 52m
Multiple Airlines
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$99
This Super.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 2/26![Frontier logo]()
$101
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/122:09 pm
ORD
- CLT
1 stop6h 52m
Multiple Airlines
Fri 5/159:26 pm
CLT
- ORD
Nonstop2h 27m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:53 pm
ORD
- CLT
1 stop9h 51m
Multiple Airlines
Fri 5/159:26 pm
CLT
- ORD
Nonstop2h 27m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$105
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:00 pm
ORD
- CLT
Nonstop2h 14m
Frontier
Mon 4/139:40 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Deal found 3/2![Frontier logo]()
$106
This Frontier deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:24 pm
ORD
- CLT
1 stop11h 54m
Frontier
Fri 5/159:26 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Deal found 2/26![Frontier logo]()
$108
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:07 am
ORD
- HHH
1 stop7h 15m
Delta
Tue 5/194:05 pm
HHH
- ORD
1 stop7h 31m
Delta
Deal found 2/27![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:49 am
ORD
- HHH
1 stop4h 33m
Delta
Tue 6/24:05 pm
HHH
- ORD
1 stop7h 31m
Delta
Deal found 3/2![Delta logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:27 pm
ORD
- CAE
1 stop27h 25m
Multiple Airlines
Mon 4/276:42 pm
CAE
- ORD
2 stops23h 18m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$206
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 3, 2026.
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/77:05 am
ORD
- CLT
Nonstop2h 23m
United Airlines
Sat 4/115:35 pm
CLT
- ORD
Nonstop2h 25m
United Airlines
Deal found 2/25![United Airlines logo]()
$161
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/269:49 am
ORD
- HHH
1 stop4h 33m
Delta
Tue 6/24:05 pm
HHH
- ORD
1 stop7h 31m
Delta
Deal found 2/28![Delta logo]()
$203
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:40 pm
ORD
- GSP
1 stop6h 35m
Southwest
Thu 4/166:25 am
GSP
- ORD
2 stops10h 05m
Southwest
Deal found 3/1![Southwest logo]()
$264
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:07 am
ORD
- CLT
Nonstop2h 23m
United Airlines
Mon 5/188:05 am
CLT
- ORD
Nonstop2h 18m
United Airlines
Deal found 2/27![United Airlines logo]()
$177
This KAYAK deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:00 am
ORD
- HHH
2 stops10h 09m
American Airlines
Sat 4/256:50 pm
HHH
- ORD
1 stop6h 04m
American Airlines
Deal found 3/2![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:45 pm
ORD
- CLT
Nonstop2h 18m
United Airlines
Wed 4/86:15 am
CLT
- ORD
Nonstop2h 28m
United Airlines
Deal found 2/26![United Airlines logo]()
$189
This Mytrip deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/34:36 pm
ORD
- MYR
3 stops27h 12m
Spirit Airlines
Sun 4/59:49 pm
MYR
- ORD
2 stops23h 02m
Spirit Airlines
Deal found 2/25![Spirit Airlines logo]()
$478
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
ORD
- CAE
1 stop4h 17m
Delta
Sun 7/195:40 am
CAE
- ORD
1 stop5h 24m
Delta
Deal found 2/27![Delta logo]()
$254
This United Airlines deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 am
ORD
- GSP
Nonstop1h 56m
United Airlines
Sun 4/56:30 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 2/28![United Airlines logo]()
$218
This Delta deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:05 am
ORD
- CAE
1 stop7h 49m
Delta
Tue 5/194:34 pm
CAE
- ORD
1 stop7h 02m
Delta
Deal found 2/28![Delta logo]()
$254
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:00 am
ORD
- GSP
Nonstop1h 56m
United Airlines
Mon 4/206:30 am
GSP
- ORD
Nonstop2h 24m
United Airlines
Deal found 2/26![United Airlines logo]()
$246
This Southwest deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/912:45 pm
MDW
- CHS
1 stop6h 30m
Southwest
Sun 5/106:15 am
CHS
- MDW
2 stops6h 55m
Southwest
Deal found 2/26![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:45 pm
ORD
- CLT
Nonstop2h 18m
United Airlines
Sun 4/196:15 am
CLT
- ORD
Nonstop2h 28m
United Airlines
Deal found 3/1![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:50 pm
MDW
- CHS
Nonstop2h 05m
Southwest
Tue 4/217:15 am
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 2/27![Southwest logo]()
$333
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:18 am
MDW
- SAV
1 stop4h 03m
Delta
Tue 5/54:59 pm
SAV
- MDW
1 stop6h 29m
Delta
Deal found 3/1![Delta logo]()
$303
This Delta deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
ORD
- GSP
1 stop7h 56m
Delta
Sat 4/45:40 am
GSP
- ORD
1 stop3h 50m
Delta
Deal found 2/25![Delta logo]()
$308
This Southwest deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:40 pm
MDW
- SAV
1 stop11h 40m
Southwest
Sat 3/287:10 pm
SAV
- MDW
1 stop6h 40m
Southwest
Deal found 2/28![Southwest logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:20 pm
ORD
- CLT
Nonstop2h 11m
United Airlines
Fri 3/276:15 am
CLT
- ORD
Nonstop2h 26m
United Airlines
Deal found 3/2![United Airlines logo]()
$257
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:50 am
ORD
- GSP
Nonstop1h 56m
United Airlines
Mon 4/67:42 pm
GSP
- ORD
1 stop5h 01m
United Airlines
Deal found 2/27![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/710:45 am
MDW
- CHS
1 stop5h 39m
Delta
Mon 4/135:57 pm
CHS
- MDW
1 stop5h 31m
Delta
Deal found 3/1![Delta logo]()
$318
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:00 am
MDW
- CHS
1 stop9h 20m
Southwest
Sat 5/1612:40 pm
CHS
- MDW
1 stop6h 35m
Southwest
Deal found 3/2![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 2/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:12 pm
ORD
- CLT
Nonstop2h 12m
United Airlines
Sun 4/126:15 am
CLT
- ORD
Nonstop2h 28m
United Airlines
Deal found 2/25![United Airlines logo]()
$259
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:48 am
ORD
- CAE
1 stop6h 11m
Delta
Sun 4/195:38 am
CAE
- ORD
1 stop3h 59m
Delta
Deal found 3/1![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:55 pm
MDW
- SAV
Nonstop2h 05m
Southwest
Wed 4/111:00 am
SAV
- MDW
2 stops9h 35m
Southwest
Deal found 2/27![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:50 am
ORD
- GSP
Nonstop2h 04m
United Airlines
Tue 4/77:42 pm
GSP
- ORD
1 stop5h 01m
United Airlines
Deal found 2/27![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/215:59 pm
ORD
- MYR
1 stop5h 05m
Delta
Wed 3/256:00 am
MYR
- ORD
1 stop5h 00m
Delta
Deal found 2/27![Delta logo]()
$331
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 pm
MDW
- CHS
Nonstop2h 05m
Southwest
Fri 5/297:40 am
CHS
- MDW
Nonstop2h 15m
Southwest
Deal found 3/2![Southwest logo]()
$369
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
MDW
- CHS
1 stop4h 24m
Delta
Sat 4/116:30 am
CHS
- MDW
1 stop4h 26m
Delta
Deal found 3/1![Delta logo]()
$331
This United Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:45 am
ORD
- HHH
Nonstop2h 36m
United Airlines
Tue 6/163:05 pm
HHH
- ORD
Nonstop2h 46m
United Airlines
Deal found 2/26![United Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:00 pm
MDW
- MYR
2 stops6h 50m
Southwest
Tue 4/212:10 pm
MYR
- MDW
2 stops9h 05m
Southwest
Deal found 3/1![Southwest logo]()
$379
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated March 3, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated March 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:18 pm
ORD
- CAE
1 stop21h 22m
Multiple Airlines
Mon 3/165:50 pm
CAE
- ORD
1 stop27h 01m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$207
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:11 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 3/2![Frontier logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:01 pm
ORD
- CLT
1 stop4h 52m
Multiple Airlines
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Multiple Airlines
Deal found 3/1![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Mon 3/3010:52 pm
CLT
- ORD
Nonstop2h 31m
Frontier
Deal found 2/28![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/51:02 pm
ORD
- CLT
Nonstop2h 10m
Multiple Airlines
Tue 4/79:18 am
CLT
- ORD
1 stop16h 04m
Multiple Airlines
Deal found 2/27![Multiple Airlines logo]()
$110
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:02 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Fri 4/1010:43 pm
CLT
- ORD
Nonstop2h 21m
Frontier
Deal found 3/2![Frontier logo]()
$100
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/113:00 pm
ORD
- CLT
Nonstop2h 14m
Frontier
Mon 4/139:40 pm
CLT
- ORD
Nonstop2h 27m
Frontier
Deal found 3/2![Frontier logo]()
$106
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:45 am
ORD
- CAE
Nonstop2h 06m
United Airlines
Sun 4/193:25 pm
CAE
- ORD
Nonstop2h 30m
United Airlines
Deal found 2/27![United Airlines logo]()
$209
This Super.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Thu 4/234:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 2/26![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:15 pm
ORD
- CAE
1 stop21h 37m
Multiple Airlines
Mon 4/276:42 pm
CAE
- ORD
1 stop27h 35m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$206
This Super.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 4/274:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 2/26![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 2/27![Frontier logo]()
$102
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated March 3, 2026.
This Priceline deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:30 pm
ORD
- CLT
Nonstop2h 15m
Frontier
Deal found 2/26![Frontier logo]()
$58
This Super.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:01 pm
ORD
- CLT
1 stop4h 52m
Spirit Airlines
Deal found 3/2![Spirit Airlines logo]()
$59
This Cheapflightsfares deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:01 pm
ORD
- CLT
1 stop4h 52m
Spirit Airlines
Deal found 2/26![Spirit Airlines logo]()
$60
This Mytrip deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:01 pm
ORD
- CHS
1 stop16h 07m
Spirit Airlines
Deal found 2/28![Spirit Airlines logo]()
$66
This Super.com deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/266:55 pm
ORD
- CLT
Nonstop2h 02m
Frontier
Deal found 2/27![Frontier logo]()
$66
This Expedia deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:02 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Deal found 2/28![Frontier logo]()
$67
This Mytrip deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:01 pm
ORD
- CHS
1 stop16h 08m
Spirit Airlines
Deal found 2/27![Spirit Airlines logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:30 am
MDW
- MYR
1 stop24h 14m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:30 am
MDW
- CHS
1 stop26h 38m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$69
This Mytrip deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:09 pm
ORD
- CLT
1 stop6h 52m
Spirit Airlines
Deal found 2/28![Spirit Airlines logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/217:30 am
MDW
- CHS
1 stop26h 38m
Multiple Airlines
Deal found 2/28![Multiple Airlines logo]()
$70
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:47 pm
ORD
- MYR
1 stop24h 57m
Spirit Airlines
Deal found 2/28![Spirit Airlines logo]()
$71
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated March 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $96 (Super.com) |
One-way from | $58 (Priceline) |
Popular in | December |
Cheapest in | August |
Average price | $396 |
Good round-trip deal | $260 or less |
Good one-way deal | $143 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 4/7
7:05 am-10:28 am
Nonstop2h 23m
Charlotte Douglas
Sat 4/11
5:35 pm-7:00 pm
Nonstop2h 25m
$161
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Sat 5/16
7:07 am-10:30 am
Nonstop2h 23m
Charlotte Douglas
Mon 5/18
8:05 am-9:23 am
Nonstop2h 18m
$177
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 4/1
5:45 pm-9:03 pm
Nonstop2h 18m
Charlotte Douglas
Wed 4/8
6:15 am-7:43 am
Nonstop2h 28m
$189
ChicagoHilton Head Island
ORD - HHH
ORDHHH
Chicago O'Hare Intl
Tue 5/26
9:49 am-3:22 pm
1 stop4h 33m
Hilton Head Island
Tue 6/2
4:05 pm-10:36 pm
1 stop7h 31m
$203
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Thu 4/2
6:50 am-9:46 am
Nonstop1h 56m
Greenville
Sun 4/5
6:30 am-7:54 am
Nonstop2h 24m
$218
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Fri 4/17
7:00 am-9:56 am
Nonstop1h 56m
Greenville
Mon 4/20
6:30 am-7:54 am
Nonstop2h 24m
$246
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Wed 4/15
5:45 pm-9:03 pm
Nonstop2h 18m
Charlotte Douglas
Sun 4/19
6:15 am-7:43 am
Nonstop2h 28m
$247
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Wed 7/15
6:00 am-11:17 am
1 stop4h 17m
Columbia Metropolitan
Sun 7/19
5:40 am-10:04 am
1 stop5h 24m
$254
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Thu 5/14
7:05 am-3:54 pm
1 stop7h 49m
Columbia Metropolitan
Tue 5/19
4:34 pm-10:36 pm
1 stop7h 02m
$254
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 3/24
6:20 pm-9:31 pm
Nonstop2h 11m
Charlotte Douglas
Fri 3/27
6:15 am-7:41 am
Nonstop2h 26m
$257
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CLT
ORD-CAE
ORD-CHS
MDW-MYR
MDW-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CLT
ORD-CAE
ORD-CHS
MDW-MYR
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, July is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $60). Flying from Illinois to South Carolina in February is currently the most expensive (average of $207). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 3, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 22% on airfare.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on February 21, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 3, 2026.
The most flights from USIL to USSC are scheduled on a Monday (20 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (7 on average).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated March 3, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Food
7.0
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentAnonymous,Feb 2026
DEN - BDL
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on March 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 6 airlines flying from Illinois to South Carolina
Discover the top 6 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$51 | Average$171 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$108 | Average$148 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$118 | Average$314 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$124 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$153 | Average$351 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$153 | Average$389 | FlexibilityNo cancel fee | On-time69% |