$83+ Cheap flights from Illinois to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
ORD — CHS
May 21 — May 281
Round-trip
1 adult, Economy
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Find cheap flights from Illinois to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Illinois to South Carolina
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Cheapest flights from Illinois to South CarolinaExplore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
Explore the most affordable flight options available from Illinois to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 21, 2026.
This Super.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$147
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/192:00 pm
ORD
- CLT
Nonstop2h 16m
Frontier
Thu 4/234:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Mon 4/279:54 pm
CLT
- ORD
1 stop24h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$150
This CheapOair deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:05 am
ORD
- CLT
1 stop8h 31m
Multiple Airlines
Mon 5/44:40 pm
CLT
- ORD
Nonstop2h 34m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:12 pm
ORD
- CLT
Nonstop2h 10m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$152
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Thu 4/3012:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$154
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/48:09 pm
CLT
- ORD
1 stop28h 04m
Frontier
Deal found 4/19![Frontier logo]()
$155
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Mon 5/117:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/18![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Wed 6/107:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 4/19![Southwest logo]()
$168
Best flights from Illinois to South CarolinaDiscover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
Discover carefully curated flight deals from Illinois to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 21, 2026.
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Wed 6/107:50 am
CLT
- MDW
2 stops8h 20m
Southwest
Deal found 4/19![Southwest logo]()
$183
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sat 5/309:55 am
CLT
- ORD
Nonstop2h 15m
United Airlines
Deal found 4/21![United Airlines logo]()
$184
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/293:35 pm
ORD
- GSP
1 stop7h 03m
Delta
Sat 9/51:10 pm
GSP
- ORD
1 stop6h 29m
Delta
Deal found 4/17![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:00 am
MDW
- CLT
Nonstop2h 10m
Southwest
Wed 8/126:35 pm
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 4/20![Southwest logo]()
$244
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Tue 6/98:05 am
CLT
- ORD
Nonstop2h 17m
United Airlines
Deal found 4/19![United Airlines logo]()
$259
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:15 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Mon 6/157:05 pm
CLT
- MDW
Nonstop2h 05m
Southwest
Deal found 4/21![Southwest logo]()
$244
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:22 pm
ORD
- CHS
1 stop4h 54m
Delta
Tue 6/303:45 pm
CHS
- ORD
1 stop6h 00m
Delta
Deal found 4/21![Delta logo]()
$282
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:15 am
ORD
- MYR
Nonstop2h 27m
United Airlines
Sat 5/2311:25 am
MYR
- ORD
Nonstop2h 45m
United Airlines
Deal found 4/21![United Airlines logo]()
$273
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:05 am
ORD
- CAE
1 stop7h 20m
Delta
Sun 6/147:39 pm
CAE
- ORD
1 stop5h 20m
Delta
Deal found 4/20![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:40 pm
ORD
- GSP
1 stop6h 35m
Southwest
Tue 5/126:45 am
GSP
- ORD
1 stop7h 05m
Southwest
Deal found 4/20![Southwest logo]()
$269
This United Airlines deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:35 am
ORD
- CAE
Nonstop2h 10m
United Airlines
Mon 6/87:45 pm
CAE
- ORD
1 stop4h 41m
United Airlines
Deal found 4/18![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:30 am
ORD
- CAE
1 stop4h 41m
Delta
Mon 6/87:39 pm
CAE
- ORD
1 stop5h 20m
Delta
Deal found 4/19![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:20 am
MDW
- CHS
2 stops7h 35m
Southwest
Mon 8/247:00 am
CHS
- MDW
Nonstop2h 10m
Southwest
Deal found 4/21![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:50 pm
ORD
- GSP
Nonstop2h 08m
United Airlines
Wed 5/2010:33 am
GSP
- ORD
1 stop4h 55m
United Airlines
Deal found 4/21![United Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:06 pm
ORD
- CAE
1 stop4h 38m
Delta
Wed 5/277:01 am
CAE
- ORD
1 stop7h 15m
Delta
Deal found 4/20![Delta logo]()
$289
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:35 am
ORD
- GSP
1 stop7h 47m
Delta
Sun 7/58:52 am
GSP
- ORD
1 stop6h 37m
Delta
Deal found 4/18![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/206:15 pm
ORD
- CLT
Nonstop2h 14m
United Airlines
Sun 6/286:15 am
CLT
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/20![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:40 pm
ORD
- GSP
1 stop6h 55m
Southwest
Mon 6/16:25 am
GSP
- ORD
2 stops10h 05m
Southwest
Deal found 4/21![Southwest logo]()
$300
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:30 pm
ORD
- GSP
1 stop7h 05m
Delta
Mon 6/157:10 am
GSP
- ORD
1 stop6h 29m
Delta
Deal found 4/17![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
ORD
- CHS
Nonstop2h 23m
United Airlines
Sun 5/316:00 am
CHS
- ORD
Nonstop2h 33m
United Airlines
Deal found 4/21![United Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:55 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Tue 6/234:20 pm
CLT
- MDW
1 stop6h 40m
Southwest
Deal found 4/16![Southwest logo]()
$301
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 am
ORD
- GSP
1 stop4h 43m
Delta
Mon 7/203:06 pm
GSP
- ORD
1 stop6h 27m
Delta
Deal found 4/18![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:00 am
ORD
- CHS
Nonstop2h 23m
United Airlines
Wed 6/37:47 pm
CHS
- ORD
1 stop4h 39m
United Airlines
Deal found 4/21![United Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:15 am
MDW
- CLT
2 stops10h 35m
Southwest
Tue 5/267:20 pm
CLT
- MDW
1 stop3h 55m
Southwest
Deal found 4/19![Southwest logo]()
$309
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:03 am
ORD
- HHH
1 stop6h 26m
Delta
Tue 7/1412:11 pm
HHH
- ORD
1 stop5h 33m
Delta
Deal found 4/16![Delta logo]()
$289
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:15 am
ORD
- MYR
Nonstop2h 27m
United Airlines
Fri 5/223:08 pm
MYR
- ORD
Nonstop2h 34m
United Airlines
Deal found 4/20![United Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Sun 5/177:00 am
CLT
- MDW
Nonstop2h 00m
Southwest
Deal found 4/18![Southwest logo]()
$317
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:03 am
ORD
- HHH
1 stop6h 26m
Delta
Mon 7/1312:11 pm
HHH
- ORD
2 stops8h 19m
Delta
Deal found 4/16![Delta logo]()
$294
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:15 pm
ORD
- CAE
1 stop4h 44m
United Airlines
Tue 5/262:29 pm
CAE
- ORD
Nonstop2h 24m
United Airlines
Deal found 4/16![United Airlines logo]()
$318
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:05 pm
MDW
- CLT
Nonstop1h 55m
Southwest
Sun 5/316:10 am
CLT
- MDW
1 stop5h 05m
Southwest
Deal found 4/20![Southwest logo]()
$318
Last-minute flights from Illinois to South CarolinaDiscover last-minute flight deals from Illinois to South Carolina. Data last updated April 21, 2026 and is based on user searches.
Discover last-minute flight deals from Illinois to South Carolina. Data last updated April 21, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 4/264:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/18![Frontier logo]()
$147
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Fri 4/244:40 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Tue 4/2812:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:16 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Thu 4/3012:50 pm
CLT
- ORD
1 stop9h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Mon 4/279:54 pm
CLT
- ORD
1 stop24h 23m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$150
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Thu 4/304:19 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2712:37 pm
ORD
- CLT
Nonstop2h 08m
Multiple Airlines
Wed 4/2912:50 pm
CLT
- ORD
1 stop12h 34m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$159
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:16 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$151
This Expedia deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Mon 5/48:09 pm
CLT
- ORD
1 stop28h 04m
Frontier
Deal found 4/19![Frontier logo]()
$155
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/112:37 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Sun 5/34:41 pm
CLT
- ORD
Nonstop2h 34m
Frontier
Deal found 4/17![Frontier logo]()
$157
This Frontier deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:14 am
MDW
- CLT
1 stop6h 21m
Frontier
Sat 5/28:09 pm
CLT
- MDW
1 stop12h 32m
Frontier
Deal found 4/17![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
ORD
- CLT
1 stop9h 18m
Frontier
Mon 5/117:58 pm
CLT
- ORD
1 stop28h 15m
Frontier
Deal found 4/18![Frontier logo]()
$158
One-way flights from Illinois to South CarolinaSearch for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
Search for one-way flight options from Illinois to South Carolina. Find affordable one-way fares based on user searches. Data last updated April 21, 2026.
This Trip.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/38:05 am
ORD
- MYR
1 stop11h 31m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$83
This Super.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/312:38 pm
ORD
- CLT
Nonstop2h 08m
Frontier
Deal found 4/17![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:52 pm
MDW
- CLT
1 stop25h 21m
Frontier
Deal found 4/17![Frontier logo]()
$84
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:00 pm
ORD
- CLT
Nonstop2h 11m
United Airlines
Deal found 4/21![United Airlines logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/17:52 am
ORD
- MYR
1 stop11h 15m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:52 am
ORD
- MYR
1 stop11h 44m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:52 am
ORD
- GSP
1 stop30h 06m
Multiple Airlines
Deal found 4/18![Multiple Airlines logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:11 pm
ORD
- CLT
1 stop18h 01m
Frontier
Deal found 4/21![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/184:05 pm
ORD
- CLT
1 stop19h 00m
Frontier
Deal found 4/17![Frontier logo]()
$90
This Cheapflightsfares deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:05 am
ORD
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 4/20![Spirit Airlines logo]()
$91
This Cheapflightsfares deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:05 am
ORD
- CLT
1 stop8h 06m
Spirit Airlines
Deal found 4/19![Spirit Airlines logo]()
$93
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:23 am
MDW
- CLT
1 stop6h 04m
Delta
Deal found 4/20![Delta logo]()
$94
Find flight deals from Illinois to South Carolina
Keep the following information in mind while searching for Illinois to South Carolina flight deals. Data was last updated April 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $151 (CheapOair) |
One-way from | $83 (Trip.com) |
Popular in | December |
Cheapest in | August |
Average price | $376 |
Good round-trip deal | $134 or less |
Good one-way deal | $186 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Illinois to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
Use the filters below to find and compare flights from Illinois to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Tue 6/2
6:00 pm-8:55 pm
Nonstop1h 55m
Charlotte Douglas
Wed 6/10
7:50 am-3:10 pm
2 stops8h 20m
$183
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 5/26
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Sat 5/30
9:55 am-11:10 am
Nonstop2h 15m
$184
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Thu 8/6
8:00 am-11:10 am
Nonstop2h 10m
Charlotte Douglas
Wed 8/12
6:35 pm-7:35 pm
Nonstop2h 00m
$244
ChicagoCharlotte
MDW - CLT
MDWCLT
Chicago Midway
Wed 6/10
6:15 pm-9:10 pm
Nonstop1h 55m
Charlotte Douglas
Mon 6/15
7:05 pm-8:10 pm
Nonstop2h 05m
$244
ChicagoCharlotte
ORD - CLT
ORDCLT
Chicago O'Hare Intl
Tue 6/2
6:15 pm-9:29 pm
Nonstop2h 14m
Charlotte Douglas
Tue 6/9
8:05 am-9:22 am
Nonstop2h 17m
$259
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Mon 5/11
2:40 pm-10:15 pm
1 stop6h 35m
Greenville
Tue 5/12
6:45 am-12:50 pm
1 stop7h 05m
$269
ChicagoMyrtle Beach
ORD - MYR
ORDMYR
Chicago O'Hare Intl
Mon 5/18
7:15 am-10:42 am
Nonstop2h 27m
Myrtle Beach Intl
Sat 5/23
11:25 am-1:10 pm
Nonstop2h 45m
$273
ChicagoGreenville
ORD - GSP
ORDGSP
Chicago O'Hare Intl
Sat 8/29
3:35 pm-11:38 pm
1 stop7h 03m
Greenville
Sat 9/5
1:10 pm-6:39 pm
1 stop6h 29m
$275
ChicagoCharleston
MDW - CHS
MDWCHS
Chicago Midway
Sat 8/22
7:20 am-3:55 pm
2 stops7h 35m
Charleston
Mon 8/24
7:00 am-8:10 am
Nonstop2h 10m
$277
ChicagoColumbia
ORD - CAE
ORDCAE
Chicago O'Hare Intl
Sat 6/6
6:35 am-9:45 am
Nonstop2h 10m
Columbia Metropolitan
Mon 6/8
7:45 pm-11:26 pm
1 stop4h 41m
$279
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Illinois to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Illinois with our price prediction graph.
ORD-CLT
MDW-CLT
ORD-GSP
ORD-CHS
ORD-MYR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Illinois to South Carolina
USIL-USSC
ORD-CLT
MDW-CLT
ORD-GSP
ORD-CHS
What is the cheapest month to book a flight from Illinois to South Carolina?
Currently, February is the cheapest month in which you can book a flight from Illinois to South Carolina (average of $101). Flying from Illinois to South Carolina in September is currently the most expensive (average of $741). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IL to SC?
Find hourly flight availability from Illinois to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 21, 2026.
One of the essential ways to save on airfare from Illinois to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 11% on airfare.
What is the cheapest day to fly from Illinois to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from Illinois to South Carolina. Price data was last updated on April 18, 2026.
Travelers seeking maximum savings on their Illinois to South Carolina flight should consider departing on Sunday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Illinois to South Carolina
Explore weekly flight availability from Illinois to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated April 21, 2026.
The most flights from USIL to USSC are scheduled on a Monday (18 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (15 on average).
How much does it cost to fly round-trip from Illinois to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated April 21, 2026.
Read through reviews of airlines operating flights from Illinois to South Carolina, such as Southwest,Delta, andUnited Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Illinois to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Illinois to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Illinois to South Carolina by cabin class
Find flights from Illinois to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Illinois and South Carolina flights
Browse other Illinois and South Carolina flight options. Last updated on April 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Illinois after your stay in South Carolina
Illinois to South Carolina flights
Consider these flights traveling from Illinois to South Carolina.
Top 6 airlines flying from Illinois to South Carolina
Discover the top 6 airlines that operate flights from Illinois to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$52 | Average$175 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$108 | Average$156 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$146 | Average$325 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$153 | Average$385 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$186 | Average$386 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$202 | Average$404 | FlexibilityNo cancel fee | On-time71% |