What are the cheapest airlines to fly from Santa Ana to South America one-way?

$174 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on LATAM Airlines and United Airlines, with prices starting from $310 and $314, respectively.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

What are the most popular routes from Santa Ana to South America?

The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Lima J Chavez Intl, Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado and Santa Ana J. Wayne/Orange Cnty - Sao Paulo Guarulhos Intl.

How far in advance should I book a flight from Santa Ana to South America?

Find a great deal and save up to 83% by booking at least 52 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Santa Ana to South America within the next two weeks, with the cheapest ticket starting at $491.

What is the cheapest month to fly from Santa Ana to South America?

Our data shows that February tends to be the cheapest month to fly to South America from Santa Ana. Users have commonly found prices around $665 for the month, but tickets can be as low as $401. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly from for flights from Santa Ana to South America?

Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.

Can I find deals for business class flights from Santa Ana to South America?

Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$174+ Flights from Santa Ana to South America

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Cheap flight deals from Santa Ana to South America

Round-trip from	$461 (CheapOair)
One-way from	$174 (CheapOair)
Popular in	December
Cheapest in	February
Average price	$780

From Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

Highest demand for flights based on searches. 19% potential increase in price ($158 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($42 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Thu 8/73:37 pmSNA - MDE

2 stops19h 27mSpirit Airlines

Wed 8/2012:49 amMDE - SNA

2 stops20h 46mSpirit Airlines

Deal found 7/28

$378

Thu 9/116:45 amSNA - MDE

3 stops28h 29mMultiple Airlines

Thu 9/182:09 pmMDE - SNA

3 stops33h 56mMultiple Airlines

Deal found 7/27

$504

Wed 10/83:00 pmSNA - BOG

1 stop11h 54mUnited Airlines

Sat 10/258:30 amBOG - SNA

1 stop15h 10mUnited Airlines

Deal found 7/29

$513

Wed 10/88:15 amSNA - BOG

1 stop12h 15mAmerican Airlines

Sat 10/256:30 amBOG - SNA

2 stops15h 47mAmerican Airlines

Deal found 7/29

$517

Fri 10/247:11 amSNA - CLO

2 stops32h 18mUnited Airlines

Fri 10/315:01 amCLO - SNA

2 stops18h 53mUnited Airlines

Deal found 7/28

$521

Fri 10/38:15 amSNA - MDE

1 stop10h 55mUnited Airlines

Fri 10/109:45 amMDE - SNA

1 stop27h 21mUnited Airlines

Deal found 7/28

$564

Wed 8/208:30 pmSNA - BOG

3 stops37h 30mSpirit Airlines

Mon 8/251:54 pmBOG - SNA

2 stops23h 35mSpirit Airlines

Deal found 7/28

$588

Mon 8/258:05 amSNA - LIM

1 stop12h 55mUnited Airlines

Mon 9/812:40 amLIM - SNA

2 stops21h 48mUnited Airlines

Deal found 7/28

$645

Wed 11/269:20 pmSNA - BOG

1 stop14h 05mLATAM Airlines

Thu 12/49:00 amBOG - SNA

1 stop12h 39mLATAM Airlines

Deal found 7/29

$651

Tue 8/266:45 amSNA - LIM

3 stops34h 35mMultiple Airlines

Mon 9/810:05 amLIM - SNA

3 stops38h 00mMultiple Airlines

Deal found 7/28

$675

Thu 8/146:45 amSNA - UIO

3 stops29h 55mMultiple Airlines

Fri 8/223:50 pmUIO - SNA

3 stops29h 45mMultiple Airlines

Deal found 7/29

$675

Mon 9/85:58 pmSNA - BOG

2 stops21h 09mCopa Airlines

Sat 9/206:17 pmBOG - SNA

2 stops29h 48mCopa Airlines

Deal found 7/27

$703

Best flights from Santa Ana to South America
Discover carefully curated flight deals from Santa Ana to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Sat 8/94:52 pmSNA - MDE

2 stops18h 20mSpirit Airlines

Sun 8/1712:49 amMDE - SNA

2 stops22h 32mSpirit Airlines

Deal found 7/29

$461

Thu 9/116:45 amSNA - MDE

3 stops28h 29mMultiple Airlines

Thu 9/182:09 pmMDE - SNA

3 stops33h 56mMultiple Airlines

Deal found 7/27

$504

Wed 10/83:00 pmSNA - BOG

1 stop11h 54mUnited Airlines

Sat 10/258:30 amBOG - SNA

1 stop15h 10mUnited Airlines

Deal found 7/29

$513

Wed 10/88:15 amSNA - BOG

1 stop12h 15mAmerican Airlines

Sat 10/256:30 amBOG - SNA

2 stops15h 47mAmerican Airlines

Deal found 7/29

$517

Wed 11/269:20 pmSNA - BOG

1 stop14h 05mLATAM Airlines

Thu 12/49:00 amBOG - SNA

1 stop12h 39mLATAM Airlines

Deal found 7/29

$651

Mon 9/85:58 pmSNA - BOG

2 stops21h 09mCopa Airlines

Sat 9/206:17 pmBOG - SNA

2 stops29h 48mCopa Airlines

Deal found 7/27

$703

Mon 8/117:12 pmSNA - BOG

2 stops13h 43mDelta

Wed 8/131:35 amBOG - SNA

2 stops17h 38mDelta

Deal found 7/28

$723

Mon 10/2712:25 pmSNA - GRU

2 stops42h 10mAir Canada

Fri 10/319:10 pmGRU - SNA

2 stops43h 11mAir Canada

Deal found 7/28

$923

Fri 10/247:11 amSNA - CLO

2 stops32h 18mUnited Airlines

Fri 10/315:01 amCLO - SNA

2 stops18h 53mUnited Airlines

Deal found 7/28

$521

Wed 8/208:30 pmSNA - BOG

3 stops37h 30mSpirit Airlines

Mon 8/251:54 pmBOG - SNA

2 stops23h 35mSpirit Airlines

Deal found 7/28

$588

Fri 10/38:15 amSNA - MDE

1 stop10h 55mUnited Airlines

Fri 10/109:45 amMDE - SNA

1 stop27h 21mUnited Airlines

Deal found 7/28

$564

Thu 8/146:45 amSNA - UIO

3 stops29h 55mMultiple Airlines

Fri 8/223:50 pmUIO - SNA

3 stops29h 45mMultiple Airlines

Deal found 7/29

$675

Last-minute flights from Santa Ana to South America
Discover last-minute flight deals from Santa Ana to South America. Data last updated July 29, 2025 and is based on user searches.

Tue 7/2912:59 pmSNA - BOG

1 stop21h 01mMultiple Airlines

Fri 8/82:00 pmBOG - SNA

2 stops23h 26mMultiple Airlines

Deal found 7/28

$705

Mon 8/49:20 pmSNA - BOG

1 stop19h 55mLATAM Airlines

Mon 8/119:00 amBOG - SNA

1 stop15h 12mLATAM Airlines

Deal found 7/28

$809

Mon 8/44:00 pmSNA - LIM

2 stops29h 00mUnited Airlines

Mon 8/1812:40 amLIM - SNA

1 stop15h 21mUnited Airlines

Deal found 7/28

$974

Mon 8/49:20 pmSNA - UIO

1 stop20h 43mLATAM Airlines

Fri 8/1511:15 pmUIO - SNA

1 stop13h 38mLATAM Airlines

Deal found 7/27

$1,009

Tue 8/57:58 pmSNA - LIM

3 stops35h 32mMultiple Airlines

Wed 8/202:15 pmLIM - SNA

3 stops31h 20mMultiple Airlines

Deal found 7/28

$1,022

Wed 8/68:15 amSNA - BOG

1 stop18h 39mUnited Airlines

Tue 8/198:30 amBOG - SNA

1 stop15h 03mUnited Airlines

Deal found 7/28

$633

Wed 8/67:11 pmSNA - BOG

2 stops13h 44mDelta

Thu 8/1410:15 amBOG - SNA

2 stops14h 08mDelta

Deal found 7/28

$813

Thu 8/73:37 pmSNA - MDE

2 stops19h 27mSpirit Airlines

Wed 8/2012:49 amMDE - SNA

2 stops20h 46mSpirit Airlines

Deal found 7/28

$378

Thu 8/77:58 pmSNA - MDE

3 stops20h 04mMultiple Airlines

Tue 8/1912:49 amMDE - SNA

3 stops20h 46mMultiple Airlines

Deal found 7/28

$567

Thu 8/79:20 pmSNA - MDE

2 stops18h 35mLATAM Airlines

Sun 8/174:37 amMDE - SNA

2 stops19h 35mLATAM Airlines

Deal found 7/28

$821

Thu 8/78:15 amSNA - MDE

1 stop18h 27mUnited Airlines

Wed 8/209:45 amMDE - SNA

1 stop13h 48mUnited Airlines

Deal found 7/28

$1,034

Thu 8/710:10 amSNA - MDE

2 stops11h 24mAmerican Airlines

Sat 8/1612:40 amMDE - SNA

2 stops16h 49mAmerican Airlines

Deal found 7/27

$1,093

One-way flights from Santa Ana to South America
Search for one-way flight options from Santa Ana to South America. Find affordable one-way fares based on user searches. Data last updated July 29, 2025.

Thu 8/218:30 pmSNA - BOG

2 stops14h 29mSpirit Airlines

Deal found 7/29

$174

Sat 10/188:04 pmSNA - MDE

2 stops15h 10mSpirit Airlines

Deal found 7/27

$175

Wed 12/105:46 pmSNA - CLO

2 stops17h 29mSpirit Airlines

Deal found 7/28

$219

Sun 11/29:30 pmSNA - BOG

1 stop13h 55mLATAM Airlines

Deal found 7/28

$310

Sun 8/243:15 pmSNA - BOG

1 stop26h 05mUnited Airlines

Deal found 7/27

$314

Thu 8/286:45 amSNA - LIM

3 stops34h 35mMultiple Airlines

Deal found 7/28

$316

Fri 10/248:04 pmSNA - LIM

2 stops22h 45mSpirit Airlines

Deal found 7/26

$317

Fri 8/2212:24 pmSNA - GRU

3 stops33h 51mMultiple Airlines

Deal found 7/27

$325

Wed 11/57:00 amSNA - UIO

2 stops14h 30mUnited Airlines

Deal found 7/29

$358

Sun 12/74:10 pmSNA - BOG

2 stops15h 00mCopa Airlines

Deal found 7/27

$367

Mon 12/85:46 pmSNA - UIO

3 stops29h 19mMultiple Airlines

Deal found 7/27

$398

Sat 9/136:45 amSNA - GIG

3 stops47h 30mMultiple Airlines

Deal found 7/29

$409

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Sat 8/9

4:52 pm-1:12 pm

2 stops18h 20m

Medellín Jose Maria Cordova Intl

Sun 8/17

12:49 am-9:21 pm

2 stops22h 32m

$461

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Thu 9/11

6:45 am-1:14 pm

3 stops28h 29m

Medellín Jose Maria Cordova Intl

Thu 9/18

2:09 pm-10:05 pm

3 stops33h 56m

$504

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

3:00 pm-4:54 am

1 stop11h 54m

Bogotá El Dorado

Sat 10/25

8:30 am-9:40 pm

1 stop15h 10m

$513

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

8:15 am-10:30 pm

1 stop12h 15m

Bogotá El Dorado

Sat 10/25

6:30 am-8:17 pm

2 stops15h 47m

$517

Santa AnaCali

SNA - CLO

SNACLO

Santa Ana J. Wayne/Orange Cnty

Fri 10/24

7:11 am-5:29 pm

2 stops32h 18m

Cali Alfonso B. Aragon Intl

Fri 10/31

5:01 am-9:54 pm

2 stops18h 53m

$521

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Fri 10/3

8:15 am-9:10 pm

1 stop10h 55m

Medellín Jose Maria Cordova Intl

Fri 10/10

9:45 am-11:06 am

1 stop27h 21m

$564

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 8/20

8:30 pm-12:00 pm

3 stops37h 30m

Bogotá El Dorado

Mon 8/25

1:54 pm-11:29 am

2 stops23h 35m

$588

Santa AnaLima

SNA - LIM

SNALIM

Santa Ana J. Wayne/Orange Cnty

Tue 8/26

8:05 am-11:00 pm

1 stop12h 55m

Lima J Chavez Intl

Tue 9/9

12:40 am-11:05 am

1 stop12h 25m

$645

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 11/26

9:20 pm-2:25 pm

1 stop14h 05m

Bogotá El Dorado

Thu 12/4

9:00 am-6:39 pm

1 stop12h 39m

$651

Santa AnaQuito

SNA - UIO

SNAUIO

Santa Ana J. Wayne/Orange Cnty

Thu 8/14

6:45 am-2:40 pm

3 stops29h 55m

Quito Mariscal Sucr

Fri 8/22

3:50 pm-7:35 pm

3 stops29h 45m

$675

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 60 results

...

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to SA?

When flying from Santa Ana to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with ANA, Delta, and LATAM Airlines from Santa Ana to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

ANA

8.4

Very good

922 reviews

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

Delta

8.0

Very good

7,977 reviews

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

LATAM Airlines

7.5

Good

1,821 reviews

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

Copa Airlines

7.5

Good

1,493 reviews

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

United Airlines

7.4

Good

8,899 reviews

ANA

8.4

Very good

922 reviews

Reviews

1 / 20

10.0

Excellent

Kenneth,Jul 2025

SFO - HND

Great food, great service, great comfort. Can’t ask for more although I’m only flying economy!

Related info for your journey

What airport do you fly from for flights from Santa Ana to South America?
Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.
What are the cheapest airlines to fly from Santa Ana to South America one-way?
$174 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on LATAM Airlines and United Airlines, with prices starting from $310 and $314, respectively.
What are the most popular routes from Santa Ana to South America?
The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Lima J Chavez Intl, Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado and Santa Ana J. Wayne/Orange Cnty - Sao Paulo Guarulhos Intl.
Can I find deals for flights from Santa Ana to South America that include hotel bookings?
Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.
Can I find deals for business class flights from Santa Ana to South America?
Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to South America?
Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Santa Ana to South America flights

Top 3 airlines flying from Santa Ana to South America

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$471	Average$942	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$522	Average$1,222	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$797	Average$935	FlexibilityNo cancel fee	On-timeN/A

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$174+ Cheap flights from Santa Ana (SNA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to South America with Cheapflights

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Cheap flight deals from Santa Ana to South America

Keep the following information in mind while searching for Santa Ana to South America flight deals. Data was last updated July 29, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South AmericaExplore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

What is the cheapest time of day to fly from SNA to SA?

Find hourly flight availability from Santa Ana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Reviews of airlines servicing South America

Peruse reviews from past customers who have flown with ANA, Delta, and LATAM Airlines from Santa Ana to South America to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Santa Ana to South America?

What are the cheapest airlines to fly from Santa Ana to South America one-way?

What are the most popular routes from Santa Ana to South America?

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

How can I find direct flights from Santa Ana to South America?

Can I find deals for business class flights from Santa Ana to South America?

What is the cheapest month to book a flight from Santa Ana to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Santa Ana to South America

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Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.