What are the cheapest airlines to fly from Santa Ana to South America one-way?

$148 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $257 and $282, respectively.

What are the most popular routes from Santa Ana to South America?

The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Medellín Jose Maria Cordova Intl, Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado and Santa Ana J. Wayne/Orange Cnty - Lima J Chavez Intl.

How far in advance should I book a flight from Santa Ana to South America?

Find a great deal and save up to 103% by booking at least 52 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Santa Ana to South America within the next two weeks, with the cheapest ticket starting at $537.

What is the cheapest month to fly from Santa Ana to South America?

Our data shows that February tends to be the cheapest month to fly to South America from Santa Ana. Users have commonly found prices around $686 for the month, but tickets can be as low as $401. Due to multiple factors, prepare for potentially higher prices in December.

What airport do you fly from for flights from Santa Ana to South America?

Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.

Can I find deals for business class flights from Santa Ana to South America?

Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$736+ Flights from Santa Ana to South America

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Cheap flight deals from Santa Ana to South America

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$323 (CheapOair)
One-way from	$148 (CheapOair)
Popular in	December
Cheapest in	February
Average price	$619

Provider with most accurate pricing for Los Angeles-Sao Paulo (SAO) flight deals.

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Provider most trusted by Cheapflights users for Los Angeles-Sao Paulo (SAO) flights.

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From Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

One-way flight from Santa Ana J. Wayne/Orange Cnty to South America

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($127 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 6% potential price decrease ($40 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in April 2025

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Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Thu 5/224:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Fri 5/302:07 pmBOG - SNA

2 stops22h 45mSpirit Airlines

Deal found 4/28

$323

Fri 6/64:27 pmSNA - MDE

2 stops18h 48mSpirit Airlines

Fri 6/132:13 pmMDE - SNA

2 stops23h 37mSpirit Airlines

Deal found 4/28

$452

Wed 10/88:00 amSNA - BOG

1 stop9h 20mUnited Airlines

Fri 10/2412:14 amBOG - SNA

2 stops22h 29mUnited Airlines

Deal found 4/28

$513

Mon 5/126:45 amSNA - MDE

3 stops37h 03mMultiple Airlines

Thu 5/155:08 pmMDE - SNA

3 stops43h 44mMultiple Airlines

Deal found 4/28

$529

Wed 6/1112:04 pmSNA - MDE

1 stop14h 38mUnited Airlines

Wed 6/189:45 amMDE - SNA

1 stop14h 15mUnited Airlines

Deal found 4/26

$558

Sun 5/254:30 pmSNA - BOG

2 stops18h 35mAmerican Airlines

Sat 5/3112:25 amBOG - SNA

1 stop12h 16mAmerican Airlines

Deal found 4/28

$605

Thu 8/148:15 amSNA - LIM

1 stop12h 45mUnited Airlines

Wed 8/2012:40 amLIM - SNA

2 stops16h 36mUnited Airlines

Deal found 4/28

$649

Sat 7/512:42 pmSNA - BOG

2 stops23h 27mMultiple Airlines

Sat 7/192:20 pmBOG - SNA

2 stops24h 20mMultiple Airlines

Deal found 4/28

$666

Sat 7/51:05 pmSNA - BOG

2 stops28h 10mDelta

Wed 7/161:35 amBOG - SNA

2 stops13h 43mDelta

Deal found 4/28

$667

Sat 5/104:27 pmSNA - LIM

3 stops24h 53mMultiple Airlines

Thu 5/156:14 amLIM - SNA

2 stops41h 03mMultiple Airlines

Deal found 4/26

$721

Sun 7/69:20 pmSNA - BOG

1 stop14h 20mLATAM Airlines

Mon 7/219:00 amBOG - SNA

1 stop15h 08mLATAM Airlines

Deal found 4/28

$728

Thu 8/146:45 amSNA - LIM

2 stops19h 25mAmerican Airlines

Thu 8/2111:45 pmLIM - SNA

2 stops16h 01mAmerican Airlines

Deal found 4/28

$757

Best flights from Santa Ana to South America
Discover carefully curated flight deals from Santa Ana to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2025.

Thu 5/224:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Fri 5/302:07 pmBOG - SNA

2 stops22h 45mSpirit Airlines

Deal found 4/28

$323

Wed 10/88:00 amSNA - BOG

1 stop9h 20mUnited Airlines

Fri 10/2412:14 amBOG - SNA

2 stops22h 29mUnited Airlines

Deal found 4/28

$513

Mon 5/126:45 amSNA - MDE

3 stops37h 03mMultiple Airlines

Thu 5/155:08 pmMDE - SNA

3 stops43h 44mMultiple Airlines

Deal found 4/28

$529

Sun 5/254:30 pmSNA - BOG

2 stops18h 35mAmerican Airlines

Sat 5/3112:25 amBOG - SNA

1 stop12h 16mAmerican Airlines

Deal found 4/28

$605

Sat 7/51:05 pmSNA - BOG

2 stops28h 10mDelta

Wed 7/161:35 amBOG - SNA

2 stops13h 43mDelta

Deal found 4/28

$667

Sun 7/69:20 pmSNA - BOG

1 stop14h 20mLATAM Airlines

Mon 7/219:00 amBOG - SNA

1 stop15h 08mLATAM Airlines

Deal found 4/28

$728

Tue 8/56:13 pmSNA - LIM

2 stops19h 27mCopa Airlines

Fri 8/227:00 amLIM - SNA

2 stops17h 12mCopa Airlines

Deal found 4/27

$846

Wed 8/271:30 pmSNA - GRU

2 stops39h 45mAir Canada

Thu 9/119:00 pmGRU - SNA

2 stops39h 55mAir Canada

Deal found 4/28

$849

Fri 6/64:27 pmSNA - MDE

2 stops18h 48mSpirit Airlines

Fri 6/132:13 pmMDE - SNA

2 stops23h 37mSpirit Airlines

Deal found 4/28

$452

Wed 6/111:14 pmSNA - MDE

2 stops13h 28mUnited Airlines

Tue 6/1712:15 amMDE - SNA

1 stop12h 44mUnited Airlines

Deal found 4/26

$558

Sat 7/512:42 pmSNA - BOG

2 stops23h 27mMultiple Airlines

Sat 7/192:20 pmBOG - SNA

2 stops24h 20mMultiple Airlines

Deal found 4/28

$666

Thu 8/148:15 amSNA - LIM

1 stop12h 45mUnited Airlines

Wed 8/2012:40 amLIM - SNA

2 stops16h 36mUnited Airlines

Deal found 4/28

$649

Last-minute flights from Santa Ana to South America
Discover last-minute flight deals from Santa Ana to South America. Data last updated April 29, 2025 and is based on user searches.

Sat 5/38:20 amSNA - MDE

1 stop10h 50mUnited Airlines

Mon 5/199:45 amMDE - SNA

1 stop13h 51mUnited Airlines

Deal found 4/28

$1,108

Sun 5/411:00 amSNA - EZE

2 stops17h 00mUnited Airlines

Thu 5/299:00 pmEZE - SNA

1 stop20h 44mUnited Airlines

Deal found 4/28

$1,444

Mon 5/51:35 pmSNA - EZE

3 stops44h 55mAir Canada

Mon 6/24:35 pmEZE - SNA

3 stops32h 12mAir Canada

Deal found 4/28

$1,189

Wed 5/710:56 amSNA - LIM

2 stops14h 29mMultiple Airlines

Tue 5/204:40 pmLIM - SNA

2 stops31h 20mMultiple Airlines

Deal found 4/28

$834

Wed 5/76:45 amSNA - LIM

1 stop12h 25mDelta

Tue 5/2011:20 pmLIM - SNA

1 stop15h 45mDelta

Deal found 4/28

$1,125

Wed 5/78:20 amSNA - EZE

2 stops27h 00mMultiple Airlines

Sun 6/19:00 pmEZE - SNA

1 stop17h 59mMultiple Airlines

Deal found 4/28

$1,377

Wed 5/77:00 pmSNA - EZE

2 stops25h 58mCopa Airlines

Sat 5/3112:06 amEZE - SNA

2 stops26h 06mCopa Airlines

Deal found 4/28

$1,390

Wed 5/711:00 amSNA - GIG

2 stops17h 15mUnited Airlines

Fri 5/309:05 pmGIG - SNA

2 stops19h 49mUnited Airlines

Deal found 4/28

$1,420

Thu 5/87:00 pmSNA - LIM

2 stops26h 00mUnited Airlines

Sun 5/1812:40 amLIM - SNA

2 stops34h 40mUnited Airlines

Deal found 4/28

$887

Thu 5/89:20 pmSNA - LIM

1 stop21h 50mLATAM Airlines

Mon 5/1911:20 pmLIM - SNA

1 stop13h 47mLATAM Airlines

Deal found 4/28

$1,084

Thu 5/82:15 pmSNA - EZE

1 stop15h 30mDelta

Mon 6/26:15 amEZE - SNA

2 stops32h 52mDelta

Deal found 4/28

$1,689

Thu 5/86:45 amSNA - EZE

2 stops19h 10mLATAM Airlines

Sat 5/3112:58 pmEZE - SNA

2 stops26h 12mLATAM Airlines

Deal found 4/28

$1,941

One-way flights from Santa Ana to South America
Search for one-way flight options from Santa Ana to South America. Find affordable one-way fares based on user searches. Data last updated April 29, 2025.

Thu 5/224:27 pmSNA - BOG

2 stops18h 38mSpirit Airlines

Deal found 4/28

$148

Thu 6/125:22 pmSNA - MDE

2 stops17h 50mSpirit Airlines

Deal found 4/27

$181

Sat 7/123:04 pmSNA - BOG

1 stop26h 16mUnited Airlines

Deal found 4/28

$257

Sun 7/1312:50 pmSNA - BOG

2 stops22h 15mAmerican Airlines

Deal found 4/28

$282

Mon 5/512:51 pmSNA - MDE

3 stops41h 27mMultiple Airlines

Deal found 4/28

$298

Thu 8/219:20 pmSNA - BOG

1 stop14h 20mLATAM Airlines

Deal found 4/28

$322

Tue 5/1312:36 pmSNA - EZE

3 stops32h 11mMultiple Airlines

Deal found 4/28

$379

Sun 6/157:40 pmSNA - GIG

3 stops34h 35mMultiple Airlines

Deal found 4/27

$401

Tue 5/2711:15 amSNA - LIM

3 stops30h 05mMultiple Airlines

Deal found 4/28

$406

Mon 5/53:36 pmSNA - BOG

2 stops15h 53mCopa Airlines

Deal found 4/28

$422

Mon 7/712:00 pmSNA - MDE

1 stop14h 42mUnited Airlines

Deal found 4/28

$457

Fri 7/259:20 pmSNA - LIM

1 stop21h 50mLATAM Airlines

Deal found 4/26

$512

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Thu 5/22

4:27 pm-1:05 pm

2 stops18h 38m

Bogotá El Dorado

Fri 5/30

2:07 pm-10:52 am

2 stops22h 45m

$323

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Fri 6/6

4:27 pm-1:15 pm

2 stops18h 48m

Medellín Jose Maria Cordova Intl

Fri 6/13

2:13 pm-11:50 am

2 stops23h 37m

$452

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Wed 10/8

8:00 am-7:20 pm

1 stop9h 20m

Bogotá El Dorado

Fri 10/24

12:14 am-8:43 pm

2 stops22h 29m

$513

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Mon 5/12

6:45 am-9:48 pm

3 stops37h 03m

Medellín Jose Maria Cordova Intl

Thu 5/15

5:08 pm-10:52 am

3 stops43h 44m

$529

Santa AnaMedellín

SNA - MDE

SNAMDE

Santa Ana J. Wayne/Orange Cnty

Wed 6/11

1:14 pm-4:42 am

2 stops13h 28m

Medellín Jose Maria Cordova Intl

Tue 6/17

12:15 am-10:59 am

1 stop12h 44m

$558

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sun 5/25

4:30 pm-1:05 pm

2 stops18h 35m

Bogotá El Dorado

Sat 5/31

12:25 am-10:41 am

1 stop12h 16m

$605

Santa AnaLima

SNA - LIM

SNALIM

Santa Ana J. Wayne/Orange Cnty

Thu 8/14

8:15 am-11:00 pm

1 stop12h 45m

Lima J Chavez Intl

Wed 8/20

12:40 am-3:16 pm

2 stops16h 36m

$649

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sat 7/5

12:42 pm-2:09 pm

2 stops23h 27m

Bogotá El Dorado

Sat 7/19

2:20 pm-12:40 pm

2 stops24h 20m

$666

Santa AnaBogotá

SNA - BOG

SNABOG

Santa Ana J. Wayne/Orange Cnty

Sat 7/5

1:05 pm-7:15 pm

2 stops28h 10m

Bogotá El Dorado

Wed 7/16

1:35 am-1:18 pm

2 stops13h 43m

$667

Santa AnaLima

SNA - LIM

SNALIM

Santa Ana J. Wayne/Orange Cnty

Sat 5/10

4:27 pm-7:20 pm

3 stops24h 53m

Lima J Chavez Intl

Thu 5/15

6:14 am-9:17 pm

2 stops41h 03m

$721

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 58 results

...

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to SA?

When flying from Santa Ana to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Rainfall in South America by month

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

Temperature in South America by month

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Reviews of airlines servicing South America

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,929 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,766 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.5

Good

1,410 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,929 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly from for flights from Santa Ana to South America?
Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to South America. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.
What are the cheapest airlines to fly from Santa Ana to South America one-way?
$148 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on United Airlines and American Airlines, with prices starting from $257 and $282, respectively.
What are the most popular routes from Santa Ana to South America?
The most popular flight routes from Santa Ana to South America are Santa Ana J. Wayne/Orange Cnty - Medellín Jose Maria Cordova Intl, Santa Ana J. Wayne/Orange Cnty - Bogotá El Dorado and Santa Ana J. Wayne/Orange Cnty - Lima J Chavez Intl.
Can I find deals for flights from Santa Ana to South America that include hotel bookings?
Yes. In addition to deals on Santa Ana to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to South America.
Can I find deals for business class flights from Santa Ana to South America?
Yes. Cheapflights offers flight deals from Santa Ana to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana to South America?
Currently, May is the cheapest month in which you can book a flight from Santa Ana to South America (average of $359). Flying from Santa Ana to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Santa Ana to South America flights

Top 3 airlines flying from Santa Ana to South America

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$431	Average$962	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$499	Average$1,225	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$788	Average$905	FlexibilityNo cancel fee	On-time81%

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$148+ Cheap flights from Santa Ana (SNA) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to South America with Cheapflights

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3. Compare prices and book

Cheap flight deals from Santa Ana to South America

Keep the following information in mind while searching for Santa Ana to South America flight deals. Data was last updated April 29, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Santa Ana to South America

Cheapest flights from Santa Ana to South AmericaExplore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to South America that are best for you.

Best time to book a flight from Santa Ana to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to South America

What is the cheapest month to book a flight from Santa Ana to South America?

What is the cheapest time of day to fly from SNA to SA?

Find hourly flight availability from Santa Ana to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2025.

Rainfall in South America by month

Plan your trip to South America by taking into account the average rainfall totals by month.

Temperature in South America by month

Plan your trip to South America by taking into account the average temperature totals by month.

Reviews of airlines servicing South America

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Santa Ana to South America?

What are the cheapest airlines to fly from Santa Ana to South America one-way?

What are the most popular routes from Santa Ana to South America?

Can I find deals for flights from Santa Ana to South America that include hotel bookings?

How can I find direct flights from Santa Ana to South America?

Can I find deals for business class flights from Santa Ana to South America?

What is the cheapest month to book a flight from Santa Ana to South America?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Santa Ana to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Santa Ana to South America

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Travel Smart

Cheapest flights from Santa Ana to South America
Explore the most affordable flight options available from Santa Ana to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2025.