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South America

$538+ Cheap flights from Moline (MLI) to South America

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — BOG
Dec 29 — Jan 51
Mon 12/29
Mon 1/5
1 adult, Economy
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Find flight deals from Moline to South America

Cheapest flights from Moline to South America
Explore the most affordable flight options available from Moline to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

This Delta deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amMLI - SCL
1 stop21h 10mDelta
Tue 12/98:15 amSCL - MLI
2 stops35h 04mDelta
Deal found 11/27$804

Cheap flight deals from Moline to South America

Keep the following information in mind while searching for Moline to South America flight deals. Data was last updated November 29, 2025.

Round-trip from

$538
(United Airlines)
From Moline Quad-City to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
Use the filters below to find and compare flights from Moline to South America that are best for you.

Fly from

Moline

Fly to

South America

Route

Depart

Return

Price

MolineMedellín

MLI - MDE

MLIMDE

Moline Quad-City

Sat 1/31

6:30 am-10:05 pm

2 stops14h 35m

Medellín Jose Maria Cordova Intl

Wed 2/4

10:45 am-10:12 am

2 stops24h 27m

$538

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Fri 5/8

5:00 pm-7:00 am

1 stop13h 00m

Santiago Arturo Merino Benitez

Wed 5/20

8:40 pm-4:21 pm

1 stop20h 41m

$844

MolineCusco

MLI - CUZ

MLICUZ

Moline Quad-City

Sun 3/1

5:00 pm-9:25 am

2 stops39h 25m

Cusco Velazco Astete

Wed 3/4

9:50 pm-10:30 pm

2 stops25h 40m

$1,123

MolineSao Paulo

MLI - GRU

MLIGRU

Moline Quad-City

Sat 2/14

5:00 pm-9:35 am

1 stop13h 35m

Sao Paulo Guarulhos Intl

Wed 2/18

11:45 pm-4:18 pm

1 stop19h 33m

$1,325

MolineLa Paz

MLI - LPB

MLILPB

Moline Quad-City

Sat 4/11

10:46 am-2:10 am

2 stops14h 24m

La Paz El Alto Intl

Tue 4/14

3:20 am-4:49 pm

2 stops14h 29m

$1,711

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Fri 5/8

8:50 am-1:30 pm

3 stops27h 40m

Santiago Arturo Merino Benitez

Wed 5/20

8:15 am-10:14 am

2 stops50h 59m

$3,903

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Sat 5/2

6:55 am-7:05 am

2 stops23h 10m

$587

MolineSao Paulo

MLI - GRU

MLIGRU

Moline Quad-City

Wed 12/24

5:50 am-5:20 am

2 stops20h 30m

$758

MolineSao Paulo

MLI - GRU

MLIGRU

Moline Quad-City

Tue 12/23

1:00 pm-7:15 am

1 stop15h 15m

$758

MolineSao Paulo

MLI - GRU

MLIGRU

Moline Quad-City

Tue 12/23

2:35 pm-8:50 am

2 stops15h 15m

$759

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/28

Showing 1-10 of 11 results
1
2

Best time to book a flight from Moline to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated November 29, 2025.
Read reviews from past customers who have flown United Airlines from Moline to South America. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,058 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,058 reviews
United Airlines
7.4
Good
9,058 reviews

Crew

8.1

Entertainment

7.1

Overall

7.4

Boarding

7.7

Food

6.6

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Moline to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South America?

    Located just 4.0 mi from the city center, Moline Quad-City (MLI) is the airport most travelers will use when flying to South America from Moline.

  • How long is the flight from Moline to South America?

    For as low as $844, United Airlines can have you in South America from Moline in 13h. Moline and South America are separated by a distance of 5317 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Moline to South America one-way?

    The cheapest airlines for a one-way flight from Moline to South America are American Airlines ($587), Delta ($758), and United Airlines ($758).

  • What are the most popular routes from Moline to South America?

    The most popular flight routes from Moline to South America are Moline Quad-City - Medellín Jose Maria Cordova Intl, Moline Quad-City - Santiago Arturo Merino Benitez and Moline Quad-City - Cusco Velazco Astete.

  • Can I find deals for flights from Moline to South America that include hotel bookings?

    Yes. In addition to deals on Moline to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South America.

  • Can I find deals for business class flights from Moline to South America?

    Yes. Cheapflights offers flight deals from Moline to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Moline to South America

Discover the top airline that operate flights from Moline to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$798Average$1,077FlexibilityNo cancel feeOn-time69%

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