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South America

$315+ Cheap flights from Moline (MLI) to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — BOG
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Moline to South America

Cheapest flights from Moline to South America
Explore the most affordable flight options available from Moline to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:55 am
MLI
-
SCL
2 stops23h 05m
Delta
Wed 5/208:40 pm
SCL
-
MLI
1 stop14h 46m
Delta
Deal found 1/24$857
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/85:29 pm
MLI
-
MDE
2 stops27h 36m
United Airlines
Wed 2/1110:45 am
MDE
-
MLI
2 stops24h 26m
United Airlines
Deal found 1/25$907
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:42 pm
MLI
-
GRU
1 stop13h 48m
United Airlines
Mon 8/1710:20 pm
GRU
-
MLI
1 stop18h 45m
United Airlines
Deal found 1/25$1,122
This United Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:52 pm
MLI
-
GRU
1 stop15h 38m
United Airlines
Wed 8/1910:20 pm
GRU
-
MLI
1 stop13h 54m
United Airlines
Deal found 1/23$1,162
This Avianca deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:35 am
MLI
-
SCL
2 stops16h 40m
Avianca
Mon 8/176:10 am
SCL
-
MLI
2 stops35h 57m
Avianca
Deal found 1/23$1,445
This Delta deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:00 am
MLI
-
CUZ
2 stops21h 25m
Delta
Mon 8/317:50 pm
CUZ
-
MLI
2 stops20h 32m
Delta
Deal found 1/24$1,593

Find flight deals from Moline to South America

Keep the following information in mind while searching for Moline to South America flight deals. Data was last updated January 26, 2026.

Round-trip from

$857
(Delta)

One-way from

$315
(Kiwi.com)
From Moline Quad-City to South America
Search Deals
One-way flight from Moline Quad-City to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Moline to South America that are best for you.

Fly from

Moline

Fly to

South America

Route

Depart

Return

Price

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Fri 5/8

5:00 pm-7:15 am

1 stop13h 15m

Santiago Arturo Merino Benitez

Wed 5/20

8:40 pm-10:26 am

1 stop14h 46m

$857

MolineMedellín

MLI - MDE

MLIMDE

Moline Quad-City

Sun 2/8

5:29 pm-10:05 pm

2 stops27h 36m

Medellín Jose Maria Cordova Intl

Wed 2/11

10:45 am-10:11 am

2 stops24h 26m

$907

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Sat 5/2

5:47 pm-3:55 am

2 stops33h 08m

$315

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Sat 5/2

5:12 pm-7:15 am

1 stop13h 03m

$457

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Wed 2/18

6:30 am-8:50 am

2 stops23h 20m

$484

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Tue 2/17

5:01 pm-3:30 pm

2 stops19h 29m

$484

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Sat 7/25

5:55 am-6:00 am

2 stops23h 05m

$593

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Wed 2/18

6:13 am-8:05 am

1 stop22h 52m

$707

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Tue 2/17

6:00 am-5:35 am

3 stops44h 35m

$858

MolineSantiago

MLI - SCL

MLISCL

Moline Quad-City

Wed 2/18

6:00 am-11:43 pm

3 stops38h 43m

$1,454

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 11 results
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Best time to book a flight from Moline to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to South America
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Moline to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to South America?

    Located just 4.0 mi from the city center, Moline Quad-City (MLI) is the airport most travelers will use when flying to South America from Moline.

  • How long is the flight from Moline to South America?

    For as low as $857, Delta can have you in South America from Moline in 13h 15m. Moline and South America are separated by a distance of 5317 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Moline to South America?

    The most popular flight routes from Moline to South America are Moline Quad-City - Sao Paulo Guarulhos Intl, Moline Quad-City - Medellín Jose Maria Cordova Intl and Moline Quad-City - Cusco Velazco Astete.

  • Can I find deals for flights from Moline to South America that include hotel bookings?

    Yes. In addition to deals on Moline to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to South America.

  • Can I find deals for business class flights from Moline to South America?

    Yes. Cheapflights offers flight deals from Moline to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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