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South America

$296+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BOG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Mississippi to South America

Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:15 pm
BTR
-
GYE
2 stops29h 21m
United Airlines
Wed 8/1912:22 pm
GYE
-
BTR
2 stops29h 20m
United Airlines
Deal found 1/27$529
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:16 am
BTR
-
GYE
2 stops14h 20m
United Airlines
Thu 8/208:28 am
GYE
-
BTR
2 stops31h 23m
United Airlines
Deal found 1/27$539
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:16 am
BTR
-
GYE
2 stops11h 35m
United Airlines
Sun 8/1612:22 pm
GYE
-
BTR
2 stops10h 24m
United Airlines
Deal found 1/27$549
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/1511:55 am
JAN
-
BOG
1 stop17h 15m
United Airlines
Mon 3/231:30 am
BOG
-
JAN
1 stop9h 43m
United Airlines
Deal found 1/27$554
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/156:42 pm
JAN
-
BOG
2 stops18h 26m
American Airlines
Tue 3/247:05 am
BOG
-
JAN
2 stops14h 39m
American Airlines
Deal found 1/27$565
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/319:30 am
BTR
-
GYE
2 stops10h 16m
United Airlines
Tue 2/32:35 pm
GYE
-
BTR
2 stops28h 18m
United Airlines
Deal found 1/27$568
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/132:03 pm
JAN
-
BOG
1 stop8h 32m
United Airlines
Fri 3/208:15 am
BOG
-
JAN
1 stop13h 42m
United Airlines
Deal found 1/27$580
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:35 am
JAN
-
BOG
2 stops15h 35m
American Airlines
Fri 3/2011:55 pm
BOG
-
JAN
1 stop12h 02m
American Airlines
Deal found 1/27$585
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:00 am
JAN
-
BOG
1 stop10h 20m
United Airlines
Thu 8/138:30 am
BOG
-
JAN
1 stop12h 48m
United Airlines
Deal found 1/28$607
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/252:06 pm
JAN
-
BOG
1 stop14h 48m
United Airlines
Tue 6/308:30 am
BOG
-
JAN
1 stop28h 53m
United Airlines
Deal found 1/28$614
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:45 am
JAN
-
BOG
1 stop13h 40m
Delta
Tue 6/305:00 am
BOG
-
JAN
2 stops18h 20m
Delta
Deal found 1/28$618
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:16 am
BTR
-
GYE
2 stops14h 20m
United Airlines
Fri 8/148:28 am
GYE
-
BTR
2 stops14h 18m
United Airlines
Deal found 1/27$620

Find flight deals from Mississippi to South America

Keep the following information in mind while searching for Mississippi to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$529
(United Airlines)

One-way from

$296
(Avianca Connect)
From Mississippi to South America
Search Deals
One-way flight from Mississippi to South America
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Fly from

Mississippi

Fly to

South America

Route

Depart

Return

Price

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sun 5/10

6:15 pm-8:51 pm

2 stops26h 36m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

8:28 am-8:01 pm

2 stops35h 33m

$529

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sun 5/10

6:15 pm-11:36 pm

2 stops29h 21m

Guayaquil Jose Joaquin de Olmedo

Wed 8/19

12:22 pm-5:42 pm

2 stops29h 20m

$529

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sun 5/10

6:15 pm-11:36 pm

2 stops29h 21m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

12:22 pm-8:01 pm

2 stops31h 39m

$529

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sun 5/10

6:15 pm-8:51 pm

2 stops26h 36m

Guayaquil Jose Joaquin de Olmedo

Tue 8/18

12:22 pm-5:42 pm

2 stops29h 20m

$529

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 5/8

6:15 pm-8:51 pm

2 stops26h 36m

Guayaquil Jose Joaquin de Olmedo

Wed 8/19

8:28 am-10:46 pm

2 stops14h 18m

$539

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 5/8

9:16 am-8:51 pm

2 stops11h 35m

Guayaquil Jose Joaquin de Olmedo

Tue 8/18

12:22 pm-1:22 pm

2 stops25h 00m

$539

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 5/9

5:00 am-8:51 pm

2 stops15h 51m

Guayaquil Jose Joaquin de Olmedo

Mon 8/17

12:22 pm-3:51 pm

2 stops27h 29m

$539

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 5/8

9:16 am-11:36 pm

2 stops14h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

8:28 am-3:51 pm

2 stops31h 23m

$539

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 5/9

9:16 am-8:51 pm

2 stops11h 35m

Guayaquil Jose Joaquin de Olmedo

Wed 8/19

8:28 am-1:22 pm

2 stops28h 54m

$539

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 5/9

9:16 am-11:36 pm

2 stops14h 20m

Guayaquil Jose Joaquin de Olmedo

Thu 8/20

8:28 am-3:51 pm

2 stops31h 23m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 42 results
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Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mississippi to South America?

    United Airlines, American Airlines, and Avianca can get you from Mississippi to South America in just under 16h 45m. Your travel time can differ by up to 9h 51m. Mississippi and South America are separated by a distance of 3556 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mississippi to South America that include hotel bookings?

    Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

  • Can I find deals for business class flights from Mississippi to South America?

    Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Mississippi to South America

Discover the top 2 airlines that operate flights from Mississippi to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$538Average$725FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$544Average$653FlexibilityNo cancel feeOn-time69%

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