How long is the flight from Mississippi to South America?

Spirit Airlines, Delta, and United Airlines can get you from Mississippi to South America in just under 14h 20m. Your travel time can differ by up to 2h 25m. Mississippi and South America are separated by a distance of 3082 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Can I find deals for flights from Mississippi to South America that include hotel bookings?

Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

Can I find deals for business class flights from Mississippi to South America?

Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$179+ Flights from Mississippi to South America

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Cheap flight deals from Mississippi to South America

Most accurate provider	AranGrant 2 stars
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Round-trip from	$468 (Priceline)
One-way from	$179 (Kiwi.com)

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Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Thu 12/117:42 pmMEM - CTG

2 stops16h 28mSpirit Airlines

Thu 12/182:15 pmCTG - MEM

3 stops30h 07mSpirit Airlines

Deal found 10/29

$541

Thu 12/1110:44 amMEM - CTG

2 stops9h 46mAmerican Airlines

Thu 12/188:00 amCTG - MEM

1 stop10h 52mAmerican Airlines

Deal found 10/29

$553

Fri 12/268:17 pmMEM - CTG

2 stops15h 53mSpirit Airlines

Mon 12/292:15 pmCTG - MEM

2 stops30h 07mSpirit Airlines

Deal found 10/29

$576

Tue 12/237:11 pmMEM - LIM

2 stops28h 39mMultiple Airlines

Wed 12/3111:37 pmLIM - MEM

1 stop20h 30mMultiple Airlines

Deal found 10/28

$579

Mon 12/12:21 pmBTR - LIM

1 stop13h 39mMultiple Airlines

Mon 12/812:15 pmLIM - BTR

1 stop10h 38mMultiple Airlines

Deal found 10/29

$595

Mon 12/16:00 amBTR - LIM

1 stop14h 20mDelta

Sun 12/712:15 amLIM - BTR

2 stops18h 59mDelta

Deal found 10/29

$600

Thu 11/137:25 pmMEM - CTG

2 stops16h 50mSpirit Airlines

Sun 11/162:20 pmCTG - MEM

2 stops30h 40mSpirit Airlines

Deal found 10/29

$600

Fri 11/286:00 amMEM - LIM

1 stop14h 20mLATAM Airlines

Wed 12/1012:15 pmLIM - MEM

1 stop21h 16mLATAM Airlines

Deal found 10/28

$611

Fri 11/286:00 amMEM - LIM

1 stop14h 20mDelta

Wed 12/108:50 amLIM - MEM

2 stops15h 33mDelta

Deal found 10/27

$615

Fri 12/268:17 pmMEM - CTG

2 stops15h 53mMultiple Airlines

Mon 12/2911:28 amCTG - MEM

3 stops33h 14mMultiple Airlines

Deal found 10/29

$646

Tue 12/238:17 pmMEM - CTG

2 stops15h 53mSpirit Airlines

Wed 12/312:15 pmCTG - MEM

2 stops30h 07mSpirit Airlines

Deal found 10/30

$647

Fri 11/78:55 pmMEM - CTG

2 stops15h 20mMultiple Airlines

Mon 11/105:20 pmCTG - MEM

2 stops30h 44mMultiple Airlines

Deal found 10/29

$660

Best flights from Mississippi to South America
Discover carefully curated flight deals from Mississippi to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 30, 2025.

Thu 12/117:42 pmMEM - CTG

2 stops16h 28mSpirit Airlines

Thu 12/182:15 pmCTG - MEM

3 stops30h 07mSpirit Airlines

Deal found 10/29

$541

Mon 12/12:21 pmBTR - LIM

1 stop13h 39mMultiple Airlines

Mon 12/812:15 pmLIM - BTR

1 stop10h 38mMultiple Airlines

Deal found 10/29

$595

Mon 12/16:00 amBTR - LIM

1 stop14h 20mDelta

Sun 12/712:15 amLIM - BTR

2 stops18h 59mDelta

Deal found 10/29

$600

Tue 3/176:15 amMEM - CTG

2 stops16h 45mUnited Airlines

Thu 3/196:25 amCTG - MEM

2 stops16h 58mUnited Airlines

Deal found 10/29

$611

Fri 11/286:00 amMEM - LIM

1 stop14h 20mLATAM Airlines

Tue 12/912:05 amLIM - MEM

2 stops24h 18mLATAM Airlines

Deal found 10/30

$615

Thu 12/1110:44 amMEM - CTG

2 stops9h 46mAmerican Airlines

Thu 12/188:00 amCTG - MEM

2 stops16h 57mAmerican Airlines

Deal found 10/29

$663

Fri 12/268:17 pmMEM - CTG

2 stops15h 53mSpirit Airlines

Mon 12/292:15 pmCTG - MEM

2 stops30h 07mSpirit Airlines

Deal found 10/29

$576

Tue 3/177:00 amMEM - CTG

1 stop6h 15mDelta

Thu 3/192:30 pmCTG - MEM

1 stop19h 05mDelta

Deal found 10/28

$611

Fri 11/289:00 amMEM - LIM

1 stop13h 55mUnited Airlines

Tue 12/91:50 amLIM - MEM

1 stop13h 05mUnited Airlines

Deal found 10/28

$615

Fri 12/268:17 pmMEM - CTG

2 stops15h 53mMultiple Airlines

Mon 12/2911:28 amCTG - MEM

3 stops33h 14mMultiple Airlines

Deal found 10/29

$646

Thu 11/137:25 pmMEM - CTG

2 stops16h 50mSpirit Airlines

Sun 11/162:20 pmCTG - MEM

2 stops30h 40mSpirit Airlines

Deal found 10/29

$600

Fri 11/286:00 amMEM - LIM

1 stop14h 20mDelta

Wed 12/108:50 amLIM - MEM

2 stops15h 33mDelta

Deal found 10/27

$615

Tue 3/176:20 amMEM - CTG

2 stops13h 00mAmerican Airlines

Thu 3/198:05 amCTG - MEM

1 stop15h 01mAmerican Airlines

Deal found 10/29

$722

Mon 3/2311:59 amMEM - SCL

2 stops16h 36mLATAM Airlines

Thu 3/2611:15 pmSCL - MEM

1 stop12h 20mLATAM Airlines

Deal found 10/29

$824

Sun 12/147:39 amMEM - SCL

2 stops46h 11mUnited Airlines

Sun 12/2110:45 pmSCL - MEM

1 stop13h 31mUnited Airlines

Deal found 10/29

$774

Mon 3/1611:59 amMEM - SCL

2 stops15h 51mLATAM Airlines

Thu 3/1911:15 pmSCL - MEM

1 stop12h 20mLATAM Airlines

Deal found 10/28

$824

Tue 3/319:10 amMOB - LIM

1 stop12h 00mDelta

Thu 4/211:20 pmLIM - MOB

1 stop12h 16mDelta

Deal found 10/28

$750

Mon 11/102:21 pmBTR - LIM

1 stop13h 39mMultiple Airlines

Mon 11/1712:15 pmLIM - BTR

1 stop10h 37mMultiple Airlines

Deal found 10/29

$851

Mon 11/107:00 amBTR - LIM

1 stop15h 55mUnited Airlines

Sun 11/161:50 amLIM - BTR

1 stop18h 37mUnited Airlines

Deal found 10/29

$851

Thu 11/132:21 pmBTR - LIM

1 stop13h 39mMultiple Airlines

Sun 11/1612:20 amLIM - BTR

2 stops14h 15mMultiple Airlines

Deal found 10/30

$856

Wed 11/129:30 amBTR - LIM

1 stop13h 25mUnited Airlines

Sun 11/161:50 amLIM - BTR

1 stop18h 37mUnited Airlines

Deal found 10/30

$851

Thu 11/137:39 amBTR - LIM

1 stop12h 41mDelta

Mon 11/1711:40 pmLIM - BTR

1 stop19h 28mDelta

Deal found 10/30

$851

Wed 11/1210:30 amBTR - LIM

1 stop17h 30mMultiple Airlines

Sun 11/1612:20 amLIM - BTR

2 stops20h 37mMultiple Airlines

Deal found 10/30

$856

Tue 2/1011:51 amMEM - GRU

2 stops17h 59mAmerican Airlines

Mon 2/1612:15 amGRU - MEM

2 stops17h 15mAmerican Airlines

Deal found 10/29

$1,045

Tue 2/106:00 amMEM - GRU

2 stops22h 30mLATAM Airlines

Tue 2/179:30 pmGRU - MEM

1 stop14h 38mLATAM Airlines

Deal found 10/29

$1,032

Thu 1/156:29 pmMEM - GRU

2 stops15h 11mAmerican Airlines

Mon 2/2312:15 amGRU - MEM

2 stops20h 00mAmerican Airlines

Deal found 10/28

$1,051

Tue 11/182:21 pmBTR - BOG

2 stops22h 24mDelta

Wed 1/75:00 amBOG - BTR

2 stops18h 03mDelta

Deal found 10/30

$891

Thu 1/155:22 pmMEM - GRU

1 stop13h 13mLATAM Airlines

Tue 2/248:15 amGRU - MEM

2 stops17h 37mLATAM Airlines

Deal found 10/29

$1,032

Sun 2/15:00 pmMEM - EZE

1 stop35h 20mUnited Airlines

Mon 2/911:55 pmEZE - MEM

1 stop19h 14mUnited Airlines

Deal found 10/29

$983

Thu 2/52:00 pmJAN - EZE

1 stop16h 20mUnited Airlines

Fri 2/1310:05 pmEZE - JAN

1 stop18h 21mUnited Airlines

Deal found 10/28

$1,016

Last-minute flights from Mississippi to South America
Discover last-minute flight deals from Mississippi to South America. Data last updated October 30, 2025 and is based on user searches.

Sat 11/16:00 amMEM - LIM

1 stop17h 25mAmerican Airlines

Tue 11/1812:45 amLIM - MEM

1 stop17h 59mAmerican Airlines

Deal found 10/28

$894

Fri 11/78:55 pmMEM - CTG

2 stops15h 20mMultiple Airlines

Mon 11/105:20 pmCTG - MEM

2 stops30h 44mMultiple Airlines

Deal found 10/29

$660

Mon 11/107:00 amBTR - LIM

1 stop15h 55mUnited Airlines

Sun 11/161:50 amLIM - BTR

1 stop18h 37mUnited Airlines

Deal found 10/29

$851

Mon 11/102:21 pmBTR - LIM

2 stops13h 39mMultiple Airlines

Mon 11/171:30 pmLIM - BTR

2 stops25h 05mMultiple Airlines

Deal found 10/29

$856

Mon 11/109:30 amBTR - LIM

1 stop13h 25mUnited Airlines

Sat 11/151:50 amLIM - BTR

1 stop18h 37mUnited Airlines

Deal found 10/29

$871

Mon 11/102:21 pmBTR - LIM

2 stops13h 39mDelta

Sat 11/1512:20 amLIM - BTR

2 stops20h 37mDelta

Deal found 10/29

$876

Thu 11/137:25 pmMEM - CTG

2 stops16h 50mSpirit Airlines

Sun 11/162:20 pmCTG - MEM

2 stops30h 40mSpirit Airlines

Deal found 10/29

$600

Tue 11/182:21 pmBTR - BOG

2 stops22h 24mDelta

Wed 1/75:00 amBOG - BTR

2 stops18h 03mDelta

Deal found 10/30

$891

Fri 11/286:00 amMEM - LIM

1 stop14h 20mLATAM Airlines

Wed 12/1012:15 pmLIM - MEM

1 stop21h 16mLATAM Airlines

Deal found 10/28

$611

Fri 11/286:00 amMEM - LIM

1 stop14h 20mDelta

Wed 12/1011:40 pmLIM - MEM

1 stop9h 51mDelta

Deal found 10/27

$615

Fri 11/289:23 amMEM - LIM

2 stops13h 02mAmerican Airlines

Tue 12/912:45 amLIM - MEM

2 stops15h 38mAmerican Airlines

Deal found 10/27

$695

Fri 11/282:30 pmMEM - LIM

3 stops31h 25mMultiple Airlines

Wed 12/1011:37 pmLIM - MEM

2 stops20h 10mMultiple Airlines

Deal found 10/28

$736

One-way flights from Mississippi to South America
Search for one-way flight options from Mississippi to South America. Find affordable one-way fares based on user searches. Data last updated October 30, 2025.

Tue 1/204:19 pmMEM - CTG

2 stops19h 49mSpirit Airlines

Deal found 10/28

$179

Sun 1/1810:40 amMEM - CTG

1 stop25h 28mMultiple Airlines

Deal found 10/28

$230

Thu 12/47:42 pmMEM - LIM

2 stops25h 53mSpirit Airlines

Deal found 10/30

$234

Wed 1/144:19 pmMEM - CTG

3 stops48h 21mMultiple Airlines

Deal found 10/28

$237

Thu 1/1510:40 amMEM - CTG

2 stops18h 30mMultiple Airlines

Deal found 10/28

$246

Mon 1/195:25 pmMEM - CTG

3 stops28h 10mMultiple Airlines

Deal found 10/28

$266

Sat 1/176:17 pmMEM - CTG

1 stop17h 51mSpirit Airlines

Deal found 10/28

$283

Sat 11/153:56 pmMEM - LIM

3 stops30h 14mMultiple Airlines

Deal found 10/30

$290

Wed 1/146:00 amMEM - CTG

1 stop7h 17mDelta

Deal found 10/28

$303

Sun 11/162:30 pmMEM - SCL

3 stops60h 00mMultiple Airlines

Deal found 10/30

$349

Sun 12/218:17 pmMEM - GRU

3 stops30h 03mMultiple Airlines

Deal found 10/30

$382

Thu 12/410:32 amMEM - LIM

1 stop9h 48mLATAM Airlines

Deal found 10/30

$390

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 12/11

7:42 pm-1:10 pm

2 stops16h 28m

Cartagena Rafael Nunez

Thu 12/18

2:15 pm-7:22 pm

3 stops30h 07m

$541

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Fri 12/26

8:17 pm-1:10 pm

2 stops15h 53m

Cartagena Rafael Nunez

Mon 12/29

2:15 pm-7:22 pm

2 stops30h 07m

$576

Baton RougeLima

BTR - LIM

BTRLIM

Baton Rouge Ryan

Mon 12/1

2:21 pm-5:00 am

1 stop13h 39m

Lima J Chavez Intl

Mon 12/8

12:15 pm-9:53 pm

1 stop10h 38m

$595

Baton RougeLima

BTR - LIM

BTRLIM

Baton Rouge Ryan

Mon 12/1

6:00 am-9:20 pm

1 stop14h 20m

Lima J Chavez Intl

Sun 12/7

12:15 am-6:14 pm

2 stops18h 59m

$600

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Thu 11/13

7:25 pm-1:15 pm

2 stops16h 50m

Cartagena Rafael Nunez

Sun 11/16

2:20 pm-8:00 pm

2 stops30h 40m

$600

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Tue 3/17

6:15 am-11:00 pm

2 stops16h 45m

Cartagena Rafael Nunez

Thu 3/19

6:25 am-11:23 pm

2 stops16h 58m

$611

MemphisCartagena

MEM - CTG

MEMCTG

Memphis

Tue 3/17

7:00 am-1:15 pm

1 stop6h 15m

Cartagena Rafael Nunez

Thu 3/19

2:30 pm-9:35 am

1 stop19h 05m

$611

MemphisLima

MEM - LIM

MEMLIM

Memphis

Fri 11/28

6:00 am-9:20 pm

1 stop14h 20m

Lima J Chavez Intl

Tue 12/9

12:05 am-11:23 pm

2 stops24h 18m

$615

MemphisLima

MEM - LIM

MEMLIM

Memphis

Fri 11/28

9:00 am-11:55 pm

1 stop13h 55m

Lima J Chavez Intl

Tue 12/9

1:50 am-1:55 pm

1 stop13h 05m

$615

MemphisLima

MEM - LIM

MEMLIM

Memphis

Fri 11/28

6:00 am-9:20 pm

1 stop14h 20m

Lima J Chavez Intl

Wed 12/10

8:50 am-11:23 pm

2 stops15h 33m

$615

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 60 results

...

Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America

What is the cheapest time of day to fly from MS to SA?

When flying from Mississippi to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 50% versus a flight in the evening.

Related info for your journey

How long is the flight from Mississippi to South America?
Spirit Airlines, Delta, and United Airlines can get you from Mississippi to South America in just under 14h 20m. Your travel time can differ by up to 2h 25m. Mississippi and South America are separated by a distance of 3082 mi. This flight may include one or multiple stops.
Can I find deals for flights from Mississippi to South America that include hotel bookings?
Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.
Can I find deals for business class flights from Mississippi to South America?
Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Mississippi to South America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$476	Average$648	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$544	Average$654	FlexibilityNo cancel fee	On-time69%

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$179+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to South America with Cheapflights

1. Tell us where you want to go

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3. Compare prices and book

Cheap flight deals from Mississippi to South America

Keep the following information in mind while searching for Mississippi to South America flight deals. Data was last updated October 30, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Mississippi to South America

Cheapest flights from Mississippi to South AmericaExplore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America

What is the cheapest time of day to fly from MS to SA?

Find hourly flight availability from Mississippi to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Mississippi to South America?

Can I find deals for flights from Mississippi to South America that include hotel bookings?

How can I find direct flights from Mississippi to South America?

Can I find deals for business class flights from Mississippi to South America?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to South America

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Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.