How long is the flight from Mississippi to South America?

Delta, United Airlines, and American Airlines can get you from Mississippi to South America in just under 9h 02m. Your travel time can differ by up to 7h 28m. Mississippi and South America are separated by a distance of 2166 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in South America ranges from 0.8 - 9.4 inches per month. January is typically the wettest month, when rainfall can reach 9.4 in. July is typically the driest time to visit South America when rainfall is around 0.8 in.

If weather is an important factor for your trip to South America, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 73.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 62.6 F).

Can I find deals for flights from Mississippi to South America that include hotel bookings?

Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mississippi to South America?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.

Can I find deals for business class flights from Mississippi to South America?

Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$374+ Flights from Mississippi to South America

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Cheap flight deals from Mississippi to South America

Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Wed 12/245:10 amBTR - GYE

2 stops17h 31mUnited Airlines

Fri 12/262:35 pmGYE - BTR

2 stops27h 57mUnited Airlines

Deal found 12/14

$672

Tue 12/238:17 pmMEM - CTG

2 stops15h 53mSpirit Airlines

Wed 12/312:15 pmCTG - MEM

2 stops30h 07mSpirit Airlines

Deal found 12/14

$691

Sun 12/288:14 pmMEM - CTG

1 stop15h 56mMultiple Airlines

Wed 12/312:15 pmCTG - MEM

1 stop29h 52mMultiple Airlines

Deal found 12/14

$722

Tue 12/305:23 amJAN - BOG

1 stop17h 07mAmerican Airlines

Wed 12/3111:55 pmBOG - JAN

1 stop16h 57mAmerican Airlines

Deal found 12/14

$754

Wed 12/177:00 amBTR - BOG

1 stop14h 35mUnited Airlines

Thu 12/181:30 amBOG - BTR

1 stop15h 17mUnited Airlines

Deal found 12/14

$758

Tue 12/166:03 pmBTR - BOG

1 stop27h 32mUnited Airlines

Fri 12/198:15 amBOG - BTR

1 stop8h 32mUnited Airlines

Deal found 12/14

$766

Tue 12/236:07 pmBTR - GYE

2 stops28h 34mUnited Airlines

Fri 12/2612:20 pmGYE - BTR

2 stops33h 58mUnited Airlines

Deal found 12/14

$833

Mon 12/229:35 amBTR - GYE

2 stops31h 01mUnited Airlines

Thu 12/2512:20 pmGYE - BTR

2 stops32h 03mUnited Airlines

Deal found 12/14

$890

Tue 12/235:26 amMEM - CTG

1 stop15h 04mAmerican Airlines

Wed 12/312:30 pmCTG - MEM

1 stop11h 10mAmerican Airlines

Deal found 12/13

$895

Sun 12/216:07 pmBTR - GYE

2 stops25h 36mUnited Airlines

Wed 12/248:30 amGYE - BTR

2 stops11h 53mUnited Airlines

Deal found 12/14

$899

Mon 12/229:35 amBTR - GYE

2 stops10h 08mUnited Airlines

Fri 12/262:35 pmGYE - BTR

2 stops26h 12mUnited Airlines

Deal found 12/14

$900

Fri 12/199:35 amBTR - GYE

2 stops31h 01mUnited Airlines

Thu 12/258:30 amGYE - BTR

2 stops10h 02mUnited Airlines

Deal found 12/14

$901

Best flights from Mississippi to South America
Discover carefully curated flight deals from Mississippi to South America that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 15, 2025.

Fri 2/139:28 amJAN - BOG

1 stop9h 02mDelta

Sun 2/223:55 pmBOG - JAN

1 stop17h 46mDelta

Deal found 12/13

$473

Fri 2/277:15 amBTR - BOG

1 stop14h 20mUnited Airlines

Sun 3/88:15 amBOG - BTR

1 stop14h 30mUnited Airlines

Deal found 12/14

$483

Thu 1/296:00 amBTR - BOG

1 stop16h 30mAmerican Airlines

Thu 2/511:55 pmBOG - BTR

1 stop19h 09mAmerican Airlines

Deal found 12/14

$498

Wed 1/2812:34 pmMOB - LIM

1 stop15h 26mMultiple Airlines

Tue 2/312:15 amLIM - MOB

2 stops12h 30mMultiple Airlines

Deal found 12/14

$599

Sun 2/16:00 amMEM - EZE

2 stops21h 20mLATAM Airlines

Mon 2/97:45 amEZE - MEM

2 stops18h 28mLATAM Airlines

Deal found 12/13

$1,008

Fri 1/1612:00 pmBTR - GYE

2 stops31h 46mUnited Airlines

Mon 1/1912:20 pmGYE - BTR

2 stops28h 38mUnited Airlines

Deal found 12/14

$547

Mon 1/125:51 pmBTR - GYE

2 stops30h 49mDelta

Fri 1/164:30 pmGYE - BTR

2 stops22h 00mDelta

Deal found 12/14

$567

Wed 1/286:13 amMOB - LIM

2 stops14h 17mAmerican Airlines

Tue 2/312:45 amLIM - MOB

2 stops23h 31mAmerican Airlines

Deal found 12/14

$599

Sat 1/177:00 amBTR - GYE

2 stops12h 46mUnited Airlines

Mon 1/1912:20 pmGYE - BTR

2 stops30h 33mUnited Airlines

Deal found 12/14

$547

Wed 4/811:14 amMEM - GRU

1 stop15h 46mMultiple Airlines

Fri 5/84:05 amGRU - MEM

2 stops32h 14mMultiple Airlines

Deal found 12/15

$662

Fri 1/1612:00 pmBTR - GYE

2 stops31h 46mUnited Airlines

Thu 1/222:35 pmGYE - BTR

2 stops53h 58mUnited Airlines

Deal found 12/14

$553

Thu 1/86:18 amBTR - BOG

1 stop12h 12mDelta

Tue 1/135:00 amBOG - BTR

2 stops18h 01mDelta

Deal found 12/14

$663

Fri 1/1612:00 pmBTR - GYE

2 stops31h 46mUnited Airlines

Tue 1/202:35 pmGYE - BTR

2 stops52h 18mUnited Airlines

Deal found 12/14

$553

Sat 2/144:01 pmMOB - LIM

1 stop11h 59mMultiple Airlines

Tue 2/1712:15 pmLIM - MOB

1 stop11h 43mMultiple Airlines

Deal found 12/13

$708

Mon 1/55:51 pmBTR - BOG

1 stop19h 34mDelta

Tue 1/135:00 amBOG - BTR

2 stops18h 01mDelta

Deal found 12/14

$667

Sat 1/179:30 amBTR - GYE

2 stops13h 12mUnited Airlines

Wed 1/2112:20 pmGYE - BTR

2 stops32h 13mUnited Airlines

Deal found 12/14

$553

Sun 12/288:14 pmMEM - CTG

1 stop15h 56mMultiple Airlines

Wed 12/312:15 pmCTG - MEM

1 stop29h 52mMultiple Airlines

Deal found 12/14

$722

Sat 1/177:00 amBTR - GYE

2 stops12h 46mUnited Airlines

Thu 1/2212:20 pmGYE - BTR

2 stops32h 13mUnited Airlines

Deal found 12/14

$553

Thu 1/86:18 amBTR - BOG

1 stop12h 12mDelta

Mon 1/1211:00 pmBOG - BTR

2 stops24h 01mDelta

Deal found 12/14

$672

Wed 1/76:18 amBTR - BOG

1 stop12h 12mDelta

Mon 1/1211:00 pmBOG - BTR

2 stops24h 01mDelta

Deal found 12/14

$672

Sat 4/1811:55 amJAN - BOG

1 stop7h 25mUnited Airlines

Tue 4/2112:14 amBOG - JAN

1 stop10h 56mUnited Airlines

Deal found 12/12

$559

Mon 5/256:00 amMEM - GRU

2 stops21h 30mLATAM Airlines

Tue 6/210:50 pmGRU - MEM

1 stop21h 27mLATAM Airlines

Deal found 12/13

$1,024

Tue 1/66:18 amBTR - BOG

1 stop7h 07mDelta

Mon 1/1211:00 pmBOG - BTR

2 stops24h 01mDelta

Deal found 12/14

$672

Sat 12/275:13 amMOB - LIM

2 stops17h 12mAmerican Airlines

Wed 12/3110:55 pmLIM - MOB

2 stops20h 25mAmerican Airlines

Deal found 12/12

$996

Wed 1/287:00 amMOB - LIM

1 stop15h 55mUnited Airlines

Tue 2/31:50 amLIM - MOB

1 stop17h 34mUnited Airlines

Deal found 12/14

$594

Wed 4/83:07 pmMEM - GRU

1 stop12h 33mLATAM Airlines

Fri 5/87:00 pmGRU - MEM

2 stops17h 51mLATAM Airlines

Deal found 12/15

$1,072

Mon 1/55:51 pmBTR - BOG

1 stop24h 39mDelta

Mon 1/1211:00 pmBOG - BTR

2 stops24h 01mDelta

Deal found 12/14

$675

Mon 5/255:52 amMEM - GRU

1 stop21h 23mAmerican Airlines

Tue 6/211:15 pmGRU - MEM

1 stop19h 49mAmerican Airlines

Deal found 12/13

$1,040

Wed 1/149:30 amBTR - GYE

2 stops34h 16mUnited Airlines

Mon 1/198:34 amGYE - BTR

2 stops34h 19mUnited Airlines

Deal found 12/14

$598

Mon 5/2511:14 amMEM - GRU

2 stops35h 26mMultiple Airlines

Mon 6/11:00 amGRU - MEM

3 stops35h 19mMultiple Airlines

Deal found 12/15

$972

Last-minute flights from Mississippi to South America
Discover last-minute flight deals from Mississippi to South America. Data last updated December 15, 2025 and is based on user searches.

Sun 1/115:51 pmBTR - BOG

1 stop24h 39mDelta

Tue 1/1311:00 pmBOG - BTR

2 stops24h 01mDelta

Deal found 12/14

$640

Mon 1/125:51 pmBTR - GYE

2 stops30h 49mDelta

Fri 1/164:30 pmGYE - BTR

2 stops22h 00mDelta

Deal found 12/14

$567

Tue 1/139:30 amBTR - GYE

2 stops10h 16mUnited Airlines

Mon 1/192:35 pmGYE - BTR

2 stops26h 23mUnited Airlines

Deal found 12/14

$598

Tue 1/139:30 amBTR - GYE

2 stops10h 16mUnited Airlines

Tue 1/2012:20 pmGYE - BTR

2 stops24h 05mUnited Airlines

Deal found 12/14

$604

Wed 1/1412:00 pmBTR - GYE

2 stops10h 42mUnited Airlines

Fri 1/1612:20 pmGYE - BTR

2 stops24h 05mUnited Airlines

Deal found 12/14

$618

Fri 1/1612:00 pmBTR - GYE

2 stops31h 46mUnited Airlines

Mon 1/1912:20 pmGYE - BTR

2 stops28h 38mUnited Airlines

Deal found 12/14

$547

Fri 1/1612:00 pmBTR - GYE

2 stops28h 35mUnited Airlines

Wed 1/2112:20 pmGYE - BTR

2 stops32h 13mUnited Airlines

Deal found 12/14

$553

Fri 1/1612:00 pmBTR - GYE

2 stops10h 42mUnited Airlines

Sun 1/1812:20 pmGYE - BTR

2 stops32h 13mUnited Airlines

Deal found 12/14

$625

Mon 1/266:15 amMEM - CTG

2 stops15h 45mUnited Airlines

Thu 1/296:24 amCTG - MEM

2 stops27h 49mUnited Airlines

Deal found 12/14

$611

Wed 1/287:00 amMOB - LIM

1 stop15h 55mUnited Airlines

Tue 2/31:50 amLIM - MOB

1 stop17h 34mUnited Airlines

Deal found 12/14

$594

Wed 1/286:13 amMOB - LIM

2 stops14h 17mAmerican Airlines

Tue 2/312:45 amLIM - MOB

2 stops23h 31mAmerican Airlines

Deal found 12/14

$599

Thu 1/296:00 amBTR - BOG

1 stop16h 30mAmerican Airlines

Thu 2/511:55 pmBOG - BTR

1 stop19h 09mAmerican Airlines

Deal found 12/14

$498

One-way flights from Mississippi to South America
Search for one-way flight options from Mississippi to South America. Find affordable one-way fares based on user searches. Data last updated December 15, 2025.

Thu 3/193:00 pmMEM - GRU

2 stops36h 40mMultiple Airlines

Deal found 12/15

$374

Mon 12/299:14 amMOB - LIM

2 stops11h 56mMultiple Airlines

Deal found 12/15

$392

Mon 12/294:50 pmMOB - LIM

1 stop30h 05mUnited Airlines

Deal found 12/15

$406

Sat 12/208:17 pmMEM - GRU

3 stops40h 58mMultiple Airlines

Deal found 12/15

$638

Tue 12/234:50 pmMOB - LIM

1 stop30h 05mUnited Airlines

Deal found 12/14

$715

Sat 12/202:48 pmMEM - GRU

2 stops16h 32mUnited Airlines

Deal found 12/15

$863

Sat 12/205:00 pmMEM - GRU

1 stop13h 35mDelta

Deal found 12/13

$1,358

Find flight deals from Mississippi to South America

Most accurate provider	AranGrant 2 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$473 (Delta)
One-way from	$374 (Kiwi.com)

Provider with most accurate pricing for Jackson-Evers Intl-Sao Paulo (SAO) flight deals.

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From Mississippi to South America

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One-way flight from Mississippi to South America

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Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

Fri 2/13

9:28 am-7:30 pm

1 stop9h 02m

Bogotá El Dorado

Sun 2/22

3:55 pm-8:41 am

1 stop17h 46m

$473

Baton RougeBogotá

BTR - BOG

BTRBOG

Baton Rouge Ryan

Fri 2/27

7:15 am-10:35 pm

1 stop14h 20m

Bogotá El Dorado

Sun 3/8

8:15 am-10:45 pm

1 stop14h 30m

$483

Baton RougeBogotá

BTR - BOG

BTRBOG

Baton Rouge Ryan

Thu 1/29

6:00 am-11:30 pm

1 stop16h 30m

Bogotá El Dorado

Thu 2/5

11:55 pm-6:04 pm

1 stop19h 09m

$498

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 1/16

12:00 pm-8:46 pm

2 stops31h 46m

Guayaquil Jose Joaquin de Olmedo

Mon 1/19

12:20 pm-3:58 pm

2 stops28h 38m

$547

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 1/17

7:00 am-8:46 pm

2 stops12h 46m

Guayaquil Jose Joaquin de Olmedo

Mon 1/19

12:20 pm-5:53 pm

2 stops30h 33m

$547

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 1/16

12:00 pm-8:46 pm

2 stops31h 46m

Guayaquil Jose Joaquin de Olmedo

Thu 1/22

2:35 pm-7:33 pm

2 stops53h 58m

$553

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Fri 1/16

12:00 pm-8:46 pm

2 stops31h 46m

Guayaquil Jose Joaquin de Olmedo

Tue 1/20

2:35 pm-5:53 pm

2 stops52h 18m

$553

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 1/17

9:30 am-11:42 pm

2 stops13h 12m

Guayaquil Jose Joaquin de Olmedo

Wed 1/21

12:20 pm-7:33 pm

2 stops32h 13m

$553

Baton RougeGuayaquil

BTR - GYE

BTRGYE

Baton Rouge Ryan

Sat 1/17

7:00 am-8:46 pm

2 stops12h 46m

Guayaquil Jose Joaquin de Olmedo

Thu 1/22

12:20 pm-7:33 pm

2 stops32h 13m

$553

JacksonBogotá

JAN - BOG

JANBOG

Jackson-Evers Intl

Sat 4/18

11:55 am-7:20 pm

1 stop7h 25m

Bogotá El Dorado

Tue 4/21

12:14 am-11:10 am

1 stop10h 56m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 38 results

Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America

What is the cheapest time of day to fly from MS to SA?

When flying from Mississippi to South America, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 47% versus a flight in the evening.

Related info for your journey

How long is the flight from Mississippi to South America?
Delta, United Airlines, and American Airlines can get you from Mississippi to South America in just under 9h 02m. Your travel time can differ by up to 7h 28m. Mississippi and South America are separated by a distance of 2166 mi. This flight may include one or multiple stops.
Can I find deals for flights from Mississippi to South America that include hotel bookings?
Yes. In addition to deals on Mississippi to South America flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mississippi to South America?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to South America.
Can I find deals for business class flights from Mississippi to South America?
Yes. Cheapflights offers flight deals from Mississippi to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from Mississippi to South America

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$476	Average$648	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$544	Average$654	FlexibilityNo cancel fee	On-time69%

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$374+ Cheap flights from Mississippi to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Mississippi to South America with Cheapflights

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Cheap flight deals from Mississippi to South America

Cheapest flights from Mississippi to South AmericaExplore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

Find flight deals from Mississippi to South America

Keep the following information in mind while searching for Mississippi to South America flight deals. Data was last updated December 15, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mississippi to South America that are best for you.

Best time to book a flight from Mississippi to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Mississippi with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to South America

What is the cheapest time of day to fly from MS to SA?

Find hourly flight availability from Mississippi to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Mississippi to South America?

Can I find deals for flights from Mississippi to South America that include hotel bookings?

How can I find direct flights from Mississippi to South America?

Can I find deals for business class flights from Mississippi to South America?

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Alternative routes for Mississippi to South America

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Mississippi to South America

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Cheapest flights from Mississippi to South America
Explore the most affordable flight options available from Mississippi to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.