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South America

$99+ Cheap flights from Key Largo, FL to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — BOG
oct. 15 — oct. 221
mié. 10/15
mié. 10/22
1 adult, Economy
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Cheap flight deals from Key Largo to South America

Keep the following information in mind while searching for Key Largo to South America flight deals. Data was last updated septiembre 15, 2025.

Round-trip from

$248
(Avianca)

One-way from

$99
(eDestinos)

Popular in

January

Cheapest in

September

Average price

$537
From Key Largo to South America
Search Deals
One-way flight from Key Largo to South America
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($156 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Key Largo to South America

Cheapest flights from Key Largo to South America
Explore the most affordable flight options available from Key Largo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 15, 2025.

This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/236:50 pmMIA - MDE
Nonstop3h 25mAvianca
lun. 11/311:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 9/14$248
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 9/286:50 pmMIA - MDE
Nonstop3h 25mAvianca
mar. 10/711:50 pmMDE - MIA
Nonstop3h 35mAvianca
Deal found 9/14$249
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/235:00 pmMIA - MDE
1 stop6h 26mAvianca
lun. 10/2711:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 9/13$254
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/307:35 pmMIA - MDE
Nonstop3h 40mAvianca
jue. 11/611:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 9/15$256
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/65:24 amMIA - BOG
1 stop5h 43mCopa Airlines
dom. 11/97:00 amBOG - MIA
1 stop6h 49mCopa Airlines
Deal found 9/13$258
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/16:50 pmMIA - MDE
Nonstop3h 25mAvianca
mié. 10/811:50 pmMDE - MIA
Nonstop3h 35mAvianca
Deal found 9/14$258
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/158:15 amMIA - MDE
Nonstop3h 20mAvianca
lun. 9/227:56 pmMDE - MIA
1 stop7h 09mAvianca
Deal found 9/14$259
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/178:12 amMIA - BOG
Nonstop3h 43mLATAM Airlines
dom. 10/191:35 amBOG - MIA
Nonstop3h 56mLATAM Airlines
Deal found 9/13$260
This Avianca deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/247:55 amMIA - CTG
1 stop6h 51mAvianca
sáb. 10/257:53 pmCTG - MIA
1 stop7h 42mAvianca
Deal found 9/15$260
This Avianca deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/237:55 amMIA - BOG
Nonstop3h 30mAvianca
vie. 10/1711:20 pmBOG - MIA
Nonstop3h 45mAvianca
Deal found 9/14$261
This Avianca deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/2511:15 amMIA - CTG
1 stop6h 36mAvianca
sáb. 11/18:00 pmCTG - MIA
1 stop7h 10mAvianca
Deal found 9/13$261
This Avianca deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 10/57:55 amMIA - BOG
Nonstop3h 30mAvianca
vie. 10/316:30 pmBOG - MIA
Nonstop4h 00mAvianca
Deal found 9/12$262

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
Use the filters below to find and compare flights from Key Largo to South America that are best for you.

Fly from

Key Largo

Fly to

South America

Route

Depart

Return

Price

MiamiMedellín

MIA - MDE

MIAMDE

Miami

jue. 10/30

6:30 am-9:00 am

Nonstop3h 30m

Medellín Jose Maria Cordova Intl

jue. 11/6

9:00 pm-3:10 am

1 stop6h 10m

$255

MiamiCartagena

MIA - CTG

MIACTG

Miami

lun. 3/2

1:00 pm-7:50 pm

1 stop6h 50m

Cartagena Rafael Nunez

lun. 3/9

3:10 pm-11:30 pm

1 stop7h 20m

$261

MiamiMedellín

MIA - MDE

MIAMDE

Miami

dom. 9/28

6:50 pm-9:15 pm

Nonstop3h 25m

Medellín Jose Maria Cordova Intl

mar. 10/7

11:50 pm-4:25 am

Nonstop3h 35m

$269

MiamiMedellín

MIA - MDE

MIAMDE

Miami

mié. 11/5

4:59 am-10:56 am

1 stop5h 57m

Medellín Jose Maria Cordova Intl

mar. 11/11

10:46 am-9:45 pm

1 stop10h 59m

$271

MiamiMedellín

MIA - MDE

MIAMDE

Miami

lun. 11/3

4:59 am-2:45 pm

1 stop9h 46m

Medellín Jose Maria Cordova Intl

mar. 11/11

9:17 am-6:51 pm

1 stop9h 34m

$271

MiamiCartagena

MIA - CTG

MIACTG

Miami

mar. 2/3

5:36 am-11:01 am

1 stop5h 25m

Cartagena Rafael Nunez

mar. 2/10

12:03 pm-9:43 pm

1 stop9h 40m

$274

MiamiCartagena

MIA - CTG

MIACTG

Miami

vie. 11/14

4:59 am-2:05 pm

1 stop9h 06m

Cartagena Rafael Nunez

mié. 11/19

9:42 am-9:45 pm

1 stop12h 03m

$274

MiamiCartagena

MIA - CTG

MIACTG

Miami

jue. 11/6

4:59 am-11:01 am

1 stop6h 02m

Cartagena Rafael Nunez

mar. 11/11

6:24 am-11:36 am

1 stop5h 12m

$274

MiamiCartagena

MIA - CTG

MIACTG

Miami

lun. 11/17

5:24 am-11:01 am

1 stop5h 37m

Cartagena Rafael Nunez

mié. 11/19

6:24 am-1:49 pm

1 stop7h 25m

$274

MiamiCartagena

MIA - CTG

MIACTG

Miami

mar. 10/7

5:21 pm-8:42 am

1 stop16h 21m

Cartagena Rafael Nunez

sáb. 10/11

6:20 am-10:26 pm

1 stop15h 06m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 60 results
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Best time to book a flight from Key Largo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to South America

What is the cheapest month to book a flight from Key Largo to South America?

Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $359). Flying from Key Largo to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SA?

Find hourly flight availability from Key Largo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 15, 2025.

When flying from Key Largo to South America, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Key Largo to South America

Explore weekly flight availability from Key Largo to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated septiembre 15, 2025.

The most flights from KE9 to 0SA are scheduled on a Monday (24 on average). You will have fewer flight options on Wednesday, which is when the least amount of flights are scheduled (17 on average).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated septiembre 15, 2025.
Read through reviews of airlines operating flights from Key Largo to South America, such as Aerolineas Argentinas, Copa Airlines, and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Aerolineas Argentinas
8.1
Very good
931 reviews
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Copa Airlines
7.6
Good
1,531 reviews
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
LATAM Airlines
7.5
Good
1,847 reviews
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
American Airlines
7.2
Good
10,000 reviews
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Avianca
6.7
Okay
2,435 reviews
Aerolineas Argentinas
8.1
Very good
931 reviews

Overall

8.1

Boarding

8.0

Comfort

7.5

Crew

8.3

Entertainment

5.7

Food

6.5

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500

Related info for your journey

Find useful and relevant information for your journey from Key Largo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to South America flight route?

    Within the past month, 202 users have taken a look at flights from Key Largo to South America.

  • How long is the flight from Key Largo to South America?

    A quick flight from Key Largo to South America can take about 3h 30m. Avianca provides one of the quickest options available for as low as $255. The distance between Key Largo and South America is about 1393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to South America one-way?

    $112 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and Delta, with prices starting from $130 and $151, respectively.

  • What are the most popular routes from Key Largo to South America?

    When deciding which route to take from Key Largo to South America consider Miami - Medellín Jose Maria Cordova Intl, Miami - Buenos Aires Ministro Pistarini or Miami - Lima J Chavez Intl as they are the most popular.

  • What are the most reliable airlines from Key Largo to South America?

    Before booking your flight to South America from Key Largo, check out the most reliable airlines to get you to your destination on time: Delta (93%), United Airlines (91%), LATAM Airlines Colombia( 89%).

  • What are the cheapest flights from Key Largo to South America?

    Looking at all options, your cheapest flight can be booked for $131. While the most popular route (Miami - Medellín Jose Maria Cordova Intl) can be booked for $248 on average, our data indicates $851 when flying from Key Largo to South America.

  • Can I find deals for flights from Key Largo to South America that include hotel bookings?

    Yes. In addition to deals on Key Largo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to South America.

  • Can I find deals for business class flights from Key Largo to South America?

    Yes. Cheapflights offers flight deals from Key Largo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to South America?

    Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $359). Flying from Key Largo to South America in December is currently the most expensive (average of $664). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Key Largo to South America

Discover the top 10 airlines that operate flights from Key Largo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$116Average$429FlexibilityNo cancel feeOn-timeN/A
VolarisCheapest$143Average$218FlexibilityNo cancel feeOn-time79%
Copa AirlinesCheapest$153Average$495FlexibilityNo cancel feeOn-time70%
Spirit AirlinesCheapest$170Average$336FlexibilityNo cancel feeOn-time65%
DeltaCheapest$171Average$628FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$214Average$482FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$238Average$581FlexibilityNo cancel feeOn-time81%
JetBlueCheapest$262Average$366FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$280Average$696FlexibilityNo cancel feeOn-time71%
EmiratesCheapest$286Average$348FlexibilityNo cancel feeOn-time75%

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