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South America

$113+ Cheap flights from Key Largo, FL to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — BOG
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Key Largo to South America

Cheapest flights from Key Largo to South America
Explore the most affordable flight options available from Key Largo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/275:30 amMIA - MDE
Nonstop3h 30mAvianca
Tue 12/3011:50 pmMDE - MIA
Nonstop3h 45mAvianca
Deal found 12/15$266
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:37 pmMIA - CTG
1 stop7h 54mDelta
Mon 1/194:35 amCTG - MIA
1 stop10h 18mDelta
Deal found 12/14$281
This Copa Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:10 pmMIA - BOG
1 stop8h 10mCopa Airlines
Tue 1/2012:08 pmBOG - MIA
1 stop9h 16mCopa Airlines
Deal found 12/13$291
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/274:59 amMIA - BOG
1 stop8h 30mCopa Airlines
Mon 1/1910:00 amBOG - MIA
1 stop11h 43mCopa Airlines
Deal found 12/14$301
This LATAM Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:07 amMIA - MDE
1 stop16h 23mLATAM Airlines
Fri 1/306:30 amMDE - MIA
1 stop8h 23mLATAM Airlines
Deal found 12/14$302
This KAYAK deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/284:37 pmMIA - MDE
1 stop6h 53mLATAM Airlines
Sun 1/45:30 amMDE - MIA
1 stop9h 23mLATAM Airlines
Deal found 12/13$306
This LATAM Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 amMIA - CTG
1 stop7h 39mLATAM Airlines
Sun 12/284:35 amCTG - MIA
1 stop10h 18mLATAM Airlines
Deal found 12/14$307
This Avianca deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:05 amMIA - BOG
Nonstop3h 50mAvianca
Mon 1/1911:10 pmBOG - MIA
Nonstop4h 00mAvianca
Deal found 12/14$309
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:10 pmMIA - BOG
1 stop7h 55mCopa Airlines
Mon 1/1912:08 pmBOG - MIA
1 stop6h 48mCopa Airlines
Deal found 12/14$310
This Cheapflightsfares deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/282:05 amMIA - BOG
Nonstop3h 50mAvianca
Mon 1/1911:10 pmBOG - MIA
Nonstop4h 00mAvianca
Deal found 12/14$312
This Copa Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:47 pmMIA - BOG
1 stop11h 18mCopa Airlines
Fri 1/3012:08 pmBOG - MIA
1 stop9h 16mCopa Airlines
Deal found 12/15$313
This KAYAK deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 amMIA - MDE
2 stops10h 13mLATAM Airlines
Sun 1/43:15 pmMDE - MIA
2 stops14h 15mLATAM Airlines
Deal found 12/13$314

Find flight deals from Key Largo to South America

Keep the following information in mind while searching for Key Largo to South America flight deals. Data was last updated December 15, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$249
(Avianca)

One-way from

$113
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$837
Provider with most accurate pricing for Miami-Sao Paulo (SAO) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Miami-Sao Paulo (SAO) flights.
Search Deals
From Key Largo to South America
Search Deals
One-way flight from Key Largo to South America
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($103 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Key Largo to South America that are best for you.

Fly from

Key Largo

Fly to

South America

Route

Depart

Return

Price

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sat 1/17

5:30 am-9:00 am

Nonstop3h 30m

Medellín Jose Maria Cordova Intl

Fri 1/23

11:50 pm-3:35 am

Nonstop3h 45m

$260

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 1/20

2:05 pm-8:35 pm

1 stop6h 30m

Medellín Jose Maria Cordova Intl

Sat 1/24

6:20 pm-12:37 am

1 stop6h 17m

$271

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 1/13

4:12 pm-8:18 am

1 stop16h 06m

Medellín Jose Maria Cordova Intl

Tue 2/10

9:17 am-6:56 pm

1 stop9h 39m

$271

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 1/26

5:26 am-2:45 pm

1 stop9h 19m

Medellín Jose Maria Cordova Intl

Fri 1/30

6:26 am-9:24 pm

1 stop14h 58m

$271

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 1/20

5:26 am-3:30 pm

1 stop10h 04m

Medellín Jose Maria Cordova Intl

Fri 1/23

9:17 am-6:56 pm

1 stop9h 39m

$271

MiamiBogotá

MIA - BOG

MIABOG

Miami

Fri 2/6

5:01 am-11:07 am

1 stop6h 06m

Bogotá El Dorado

Tue 2/10

12:08 pm-9:24 pm

1 stop9h 16m

$273

MiamiBogotá

MIA - BOG

MIABOG

Miami

Fri 2/20

5:01 am-1:29 pm

1 stop8h 28m

Bogotá El Dorado

Sun 2/22

10:40 am-6:56 pm

1 stop8h 16m

$273

MiamiBogotá

MIA - BOG

MIABOG

Miami

Wed 2/4

5:36 am-8:12 pm

1 stop14h 36m

Bogotá El Dorado

Wed 2/11

6:10 am-6:56 pm

1 stop12h 46m

$273

MiamiCartagena

MIA - CTG

MIACTG

Miami

Thu 2/19

4:37 pm-12:31 am

1 stop7h 54m

Cartagena Rafael Nunez

Thu 2/26

4:17 pm-10:51 am

1 stop18h 34m

$281

MiamiCartagena

MIA - CTG

MIACTG

Miami

Fri 2/13

12:53 pm-12:31 am

1 stop11h 38m

Cartagena Rafael Nunez

Sun 2/15

4:35 am-2:53 pm

1 stop10h 18m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/13

Showing 1-10 of 60 results
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Best time to book a flight from Key Largo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to South America

What is the cheapest month to book a flight from Key Largo to South America?

Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $137). Flying from Key Largo to South America in July is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SA?

Find hourly flight availability from Key Largo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 16% on flights from Key Largo to South America by exploring options for tickets at noon.

What is the cheapest day to fly from Key Largo to South America?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to South America. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Key Largo to South America flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to South America

Explore weekly flight availability from Key Largo to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 15, 2025.

The most flights from KE9 to 0SA are scheduled on a Monday (26 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (20 on average).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated December 15, 2025.
Read through reviews of airlines operating flights from Key Largo to South America, such as Aerolineas Argentinas, Copa Airlines, and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Aerolineas Argentinas
8.1
Very good
972 reviews
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Copa Airlines
7.6
Good
1,557 reviews
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
LATAM Airlines
7.5
Good
1,892 reviews
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
American Airlines
7.2
Good
11,051 reviews
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500
Avianca
6.6
Okay
2,485 reviews
Aerolineas Argentinas
8.1
Very good
972 reviews

Food

6.5

Comfort

7.6

Boarding

8.0

Overall

8.1

Entertainment

5.8

Crew

8.4

Reviews

1 / 5
2.0
Mediocre

Paula,Aug 2025

EZE - MIA

I can not take the flight because Service dogs are not allowed. I m asking the refund of my flight. Please take care of my request # 00447290197500

Related info for your journey

Find useful and relevant information for your journey from Key Largo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to South America flight route?

    Within the past month, 161 users have taken a look at flights from Key Largo to South America.

  • How long is the flight from Key Largo to South America?

    A quick flight from Key Largo to South America can take about 3h 30m. Avianca provides one of the quickest options available for as low as $260. The distance between Key Largo and South America is about 1393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to South America one-way?

    $61 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Avianca and Arajet, with prices starting from $79 and $82, respectively.

  • What are the most popular routes from Key Largo to South America?

    When deciding which route to take from Key Largo to South America consider Miami - Medellín Jose Maria Cordova Intl, Miami - Lima J Chavez Intl or Miami - Buenos Aires Ministro Pistarini as they are the most popular.

  • What are the most reliable airlines from Key Largo to South America?

    Before booking your flight to South America from Key Largo, check out the most reliable airlines to get you to your destination on time: Delta (89%), American Airlines (86%), LATAM Airlines Colombia( 86%).

  • What are the cheapest flights from Key Largo to South America?

    Looking at all options, your cheapest flight can be booked for $138. While the most popular route (Miami - Medellín Jose Maria Cordova Intl) can be booked for $261 on average, our data indicates $1,316 when flying from Key Largo to South America.

  • Can I find deals for flights from Key Largo to South America that include hotel bookings?

    Yes. In addition to deals on Key Largo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to South America.

  • Can I find deals for business class flights from Key Largo to South America?

    Yes. Cheapflights offers flight deals from Key Largo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to South America?

    Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $137). Flying from Key Largo to South America in July is currently the most expensive (average of $208). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Key Largo to South America

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Key Largo to South America

Discover the top 10 airlines that operate flights from Key Largo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$118Average$485FlexibilityNo cancel feeOn-timeN/A
Copa AirlinesCheapest$131Average$514FlexibilityNo cancel feeOn-time70%
VolarisCheapest$143Average$198FlexibilityNo cancel feeOn-time79%
DeltaCheapest$174Average$606FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$174Average$334FlexibilityNo cancel feeOn-time65%
AviancaCheapest$217Average$491FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$238Average$637FlexibilityNo cancel feeOn-time81%
JetBlueCheapest$254Average$363FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$268Average$704FlexibilityNo cancel feeOn-time71%
EmiratesCheapest$272Average$356FlexibilityNo cancel feeOn-time75%

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