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South America

$110+ Cheap flights from Key Largo, FL to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
MIA — BOG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Key Largo to South America

Cheapest flights from Key Largo to South America
Explore the most affordable flight options available from Key Largo to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Avianca deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/191:00 pm
MIA
-
MDE
1 stop5h 55m
Avianca
Sun 2/2211:50 pm
MDE
-
MIA
Nonstop3h 45m
Avianca
Deal found 1/26$238
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:35 pm
MIA
-
MDE
Nonstop3h 40m
Avianca
Sun 2/229:00 pm
MDE
-
MIA
1 stop6h 10m
Avianca
Deal found 1/28$239
This Avianca deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:25 pm
MIA
-
MDE
1 stop6h 00m
Avianca
Wed 2/2511:30 am
MDE
-
MIA
Nonstop3h 35m
Avianca
Deal found 1/29$240
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:35 pm
MIA
-
MDE
Nonstop3h 40m
Avianca
Sun 3/1511:50 pm
MDE
-
MIA
Nonstop3h 45m
Avianca
Deal found 1/28$242
This oojo deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:50 pm
MIA
-
MDE
Nonstop3h 25m
Avianca
Mon 5/186:35 pm
MDE
-
MIA
1 stop28h 55m
Avianca
Deal found 1/27$243
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:30 am
MIA
-
MDE
Nonstop3h 30m
Avianca
Sun 3/811:50 pm
MDE
-
MIA
Nonstop3h 45m
Avianca
Deal found 1/28$244
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/271:25 pm
MIA
-
MDE
1 stop6h 00m
Avianca
Sat 2/284:15 pm
MDE
-
MIA
1 stop6h 15m
Avianca
Deal found 1/28$245
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
MIA
-
MDE
1 stop5h 55m
Avianca
Fri 2/274:15 pm
MDE
-
MIA
1 stop6h 15m
Avianca
Deal found 1/27$246
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/178:00 am
MIA
-
MDE
1 stop5h 55m
Avianca
Tue 3/2411:50 pm
MDE
-
MIA
Nonstop3h 45m
Avianca
Deal found 1/27$248
This Avianca deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/245:30 am
MIA
-
MDE
Nonstop3h 30m
Avianca
Tue 3/319:55 am
MDE
-
MIA
1 stop7h 10m
Avianca
Deal found 1/28$249
This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/138:00 am
MIA
-
MDE
1 stop5h 55m
Avianca
Mon 3/1611:50 pm
MDE
-
MIA
Nonstop3h 45m
Avianca
Deal found 1/27$250
This Super.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:45 pm
MIA
-
CTG
3 stops17h 50m
Avianca
Tue 3/35:05 pm
CTG
-
MIA
1 stop10h 05m
Avianca
Deal found 1/28$266

Find flight deals from Key Largo to South America

Keep the following information in mind while searching for Key Largo to South America flight deals. Data was last updated January 29, 2026.

Round-trip from

$238
(Avianca)

One-way from

$110
(Super.com)

Popular in

December

Cheapest in

September

Average price

$342
From Key Largo to South America
Search Deals
One-way flight from Key Largo to South America
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key Largo to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Key Largo to South America that are best for you.

Fly from

Key Largo

Fly to

South America

Route

Depart

Return

Price

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 3/2

5:30 am-9:00 am

Nonstop3h 30m

Medellín Jose Maria Cordova Intl

Sat 3/14

11:50 pm-4:35 am

Nonstop3h 45m

$242

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 3/5

1:00 pm-6:55 pm

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Mon 3/9

4:15 pm-11:30 pm

1 stop6h 15m

$244

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 2/9

7:00 am-1:20 pm

1 stop6h 20m

Medellín Jose Maria Cordova Intl

Wed 2/18

4:15 pm-10:30 pm

1 stop6h 15m

$247

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sat 2/21

7:34 am-2:15 pm

1 stop6h 41m

Medellín Jose Maria Cordova Intl

Sun 2/22

10:46 am-9:43 pm

1 stop10h 57m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sat 2/14

5:29 pm-8:18 am

1 stop14h 49m

Medellín Jose Maria Cordova Intl

Sat 2/21

6:20 pm-12:37 am

1 stop6h 17m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sun 3/1

5:01 am-10:56 am

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Sun 3/8

9:17 am-10:24 pm

1 stop12h 07m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Wed 2/11

7:34 am-2:45 pm

1 stop7h 11m

Medellín Jose Maria Cordova Intl

Thu 2/26

12:42 pm-9:24 pm

1 stop8h 42m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 2/23

7:34 am-2:15 pm

1 stop6h 41m

Medellín Jose Maria Cordova Intl

Mon 3/2

9:17 am-6:55 pm

1 stop9h 38m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Wed 2/11

5:36 am-2:45 pm

1 stop9h 09m

Medellín Jose Maria Cordova Intl

Sun 3/1

6:25 am-3:40 pm

1 stop9h 15m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Wed 2/11

5:36 am-2:45 pm

1 stop9h 09m

Medellín Jose Maria Cordova Intl

Sun 2/22

4:30 pm-12:37 am

1 stop8h 07m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from Key Largo to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Key Largo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key Largo to South America

What is the cheapest month to book a flight from Key Largo to South America?

Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $133). Flying from Key Largo to South America in July is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from KE9 to SA?

Find hourly flight availability from Key Largo to South America. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

Unlike in the evening, when flights are generally more expensive, you can save up to 14% on flights from Key Largo to South America by exploring options for tickets in the morning.

What is the cheapest day to fly from Key Largo to South America?

Use this chart to determine the cheapest time to fly round-trip from Key Largo to South America. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Key Largo to South America flight should consider departing on Wednesday at noon when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Key Largo to South America

Explore weekly flight availability from Key Largo to South America. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.

The most flights from KE9 to 0SA are scheduled on a Wednesday (25 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (19 on average).

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated January 29, 2026.
Read through reviews of airlines operating flights from Key Largo to South America, such as Aerolineas Argentinas, LATAM Airlines, and Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.
Aerolineas Argentinas
8.0
Very good
1,007 reviews
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.
LATAM Airlines
7.5
Good
1,918 reviews
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.
Copa Airlines
7.5
Good
1,560 reviews
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.
American Airlines
7.2
Good
11,206 reviews
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.
Avianca
6.6
Okay
2,492 reviews
Aerolineas Argentinas
8.0
Very good
1,007 reviews

Boarding

8.0

Food

6.5

Overall

8.0

Crew

8.4

Entertainment

5.8

Comfort

7.5

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Related info for your journey

Find useful and relevant information for your journey from Key Largo to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Key Largo to South America flight route?

    Within the past month, 145 users have taken a look at flights from Key Largo to South America.

  • How long is the flight from Key Largo to South America?

    A quick flight from Key Largo to South America can take about 3h 30m. Avianca provides one of the quickest options available for as low as $242. The distance between Key Largo and South America is about 1393 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Key Largo to South America one-way?

    $46 is the cheapest one-way deal found within the past few days, from Spirit Airlines. You may also be able to find cheap deals on Avianca and Arajet, with prices starting from $78 and $82, respectively.

  • What are the most popular routes from Key Largo to South America?

    When deciding which route to take from Key Largo to South America consider Miami - Medellín Jose Maria Cordova Intl, Miami - Buenos Aires Ministro Pistarini or Miami - Bogotá El Dorado as they are the most popular.

  • What are the most reliable airlines from Key Largo to South America?

    Before booking your flight to South America from Key Largo, check out the most reliable airlines to get you to your destination on time: LATAM Airlines Colombia (94%), LATAM Airlines (94%), Virgin Atlantic( 94%).

  • What are the cheapest flights from Key Largo to South America?

    Looking at all options, your cheapest flight can be booked for $124. While the most popular route (Miami - Medellín Jose Maria Cordova Intl) can be booked for $232 on average, our data indicates $1,081 when flying from Key Largo to South America.

  • Can I find deals for flights from Key Largo to South America that include hotel bookings?

    Yes. In addition to deals on Key Largo to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key Largo to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key Largo to South America.

  • Can I find deals for business class flights from Key Largo to South America?

    Yes. Cheapflights offers flight deals from Key Largo to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key Largo to South America?

    Currently, May is the cheapest month in which you can book a flight from Key Largo to South America (average of $133). Flying from Key Largo to South America in July is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Key Largo to South America

Discover the top 10 airlines that operate flights from Key Largo to South America. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
ArajetCheapest$106Average$431FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$119Average$581FlexibilityNo cancel feeOn-time81%
Copa AirlinesCheapest$131Average$475FlexibilityNo cancel feeOn-time70%
VolarisCheapest$143Average$197FlexibilityNo cancel feeOn-time79%
DeltaCheapest$164Average$548FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$171Average$300FlexibilityNo cancel feeOn-time65%
AviancaCheapest$183Average$467FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$206Average$382FlexibilityNo cancel feeOn-time62%
AzulCheapest$222Average$548FlexibilityNo cancel feeOn-time82%
American AirlinesCheapest$264Average$688FlexibilityNo cancel feeOn-time71%

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