South America

$110+ Cheap flights from Florida Keys to South America

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — BOG
Mar 4 — Mar 111
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Find cheap flights from Florida Keys to South America with Cheapflights

1. Tell us where you want to go

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Cheap flight deals from Florida Keys to South America

Cheapest flights from Florida Keys to South America
Explore the most affordable flight options available from Florida Keys to South America. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:50 pm
MIA
-
MDE
Nonstop3h 25m
Avianca
Wed 4/1511:00 am
MDE
-
MIA
Nonstop3h 35m
Avianca
Deal found 2/1$239
This Avianca deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/27:00 am
MIA
-
MDE
1 stop5h 55m
Avianca
Wed 3/44:15 pm
MDE
-
MIA
1 stop6h 15m
Avianca
Deal found 1/31$240
This Avianca deal was found by Cheapflights users on 1/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:25 pm
MIA
-
MDE
1 stop6h 00m
Avianca
Mon 3/29:00 pm
MDE
-
MIA
1 stop6h 10m
Avianca
Deal found 1/30$241
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:50 pm
MIA
-
MDE
Nonstop3h 25m
Avianca
Mon 4/1311:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 2/1$242
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/161:25 pm
MIA
-
MDE
1 stop6h 00m
Avianca
Sun 2/225:00 am
MDE
-
MIA
1 stop6h 30m
Avianca
Deal found 2/1$243
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 am
MIA
-
MDE
1 stop6h 20m
Avianca
Sat 4/188:45 pm
MDE
-
MIA
1 stop6h 00m
Avianca
Deal found 2/1$244
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:25 pm
MIA
-
MDE
1 stop6h 00m
Avianca
Wed 2/259:00 pm
MDE
-
MIA
1 stop6h 10m
Avianca
Deal found 2/1$245
This Kiwi.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:30 am
MIA
-
MDE
Nonstop3h 30m
Avianca
Tue 3/1011:30 am
MDE
-
MIA
Nonstop3h 35m
Avianca
Deal found 1/29$246
This Avianca deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:00 am
MIA
-
MDE
1 stop5h 55m
Avianca
Tue 4/711:50 pm
MDE
-
MIA
Nonstop3h 30m
Avianca
Deal found 1/31$248
This Avianca deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/127:35 pm
MIA
-
MDE
Nonstop3h 40m
Avianca
Tue 3/179:00 pm
MDE
-
MIA
1 stop6h 10m
Avianca
Deal found 2/1$250
This Trip.com deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:30 am
MIA
-
CTG
1 stop12h 10m
Avianca
Tue 3/310:05 pm
CTG
-
MIA
1 stop13h 25m
Avianca
Deal found 1/29$259
This Super.com deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:35 pm
MIA
-
CTG
1 stop19h 10m
Avianca
Sun 3/85:05 pm
CTG
-
MIA
1 stop10h 05m
Avianca
Deal found 1/31$260

Find flight deals from Florida Keys to South America

Keep the following information in mind while searching for Florida Keys to South America flight deals. Data was last updated February 2, 2026.

Round-trip from

$239
(Kiwi.com)

One-way from

$110
(Kiwi.com)
From Florida Keys to South America
One-way flight from Florida Keys to South America

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to South America that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Florida Keys to South America that are best for you.

Fly from

Florida Keys

Fly to

South America

Route

Depart

Return

Price

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Tue 2/24

7:00 am-12:55 pm

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Tue 3/31

7:40 pm-3:45 am

1 stop7h 05m

$244

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 3/5

7:00 am-12:55 pm

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Sun 3/8

9:00 pm-4:10 am

1 stop6h 10m

$252

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sun 3/15

6:01 am-10:56 am

1 stop5h 55m

Medellín Jose Maria Cordova Intl

Wed 3/18

6:25 am-10:42 pm

1 stop15h 17m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Sun 2/15

5:36 am-2:45 pm

1 stop9h 09m

Medellín Jose Maria Cordova Intl

Tue 3/31

5:00 am-4:40 pm

1 stop10h 40m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 2/26

5:36 am-10:56 am

1 stop5h 20m

Medellín Jose Maria Cordova Intl

Tue 3/3

5:00 am-11:07 am

1 stop6h 07m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 3/13

6:01 am-2:15 pm

1 stop9h 14m

Medellín Jose Maria Cordova Intl

Fri 3/20

12:42 pm-10:42 pm

1 stop9h 00m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 3/19

8:34 am-2:15 pm

1 stop6h 41m

Medellín Jose Maria Cordova Intl

Mon 3/23

4:30 pm-1:40 am

1 stop8h 10m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Thu 2/26

7:34 am-2:15 pm

1 stop6h 41m

Medellín Jose Maria Cordova Intl

Sun 3/1

10:46 am-9:42 pm

1 stop10h 56m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Fri 3/13

6:26 am-8:35 pm

1 stop15h 09m

Medellín Jose Maria Cordova Intl

Sun 3/22

8:37 am-1:40 am

1 stop16h 03m

$254

MiamiMedellín

MIA - MDE

MIAMDE

Miami

Mon 3/2

5:26 am-2:45 pm

1 stop9h 19m

Medellín Jose Maria Cordova Intl

Wed 3/4

12:42 pm-12:40 am

1 stop11h 58m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Showing 1-10 of 60 results
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Best time to book a flight from Florida Keys to South America

Have a flexible travel schedule? Discover the best time to fly to South America from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to South America
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing South America

Get insights into the airlines that provide service to South America. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South America. Reviews last updated February 2, 2026.
Get a feel of what it's like to fly with Aerolineas Argentinas, LATAM Airlines, and Copa Airlines from Florida Keys to South America by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Entertainment

5.8

Crew

8.4

Food

6.5

Comfort

7.5

Boarding

8.0

Overall

8.0

Reviews

1 / 6
8.0
Excellent

adam,Jan 2026

USH - EZE

Gate change was not announced. Groupings for boarding a little disorganized. Otherwise all good.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to South America. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Florida Keys to South America?

    Avianca, Copa Airlines, and GOL can get you from Florida Keys to South America in just under 5h 55m. Your travel time can differ by up to 5h 55m. Florida Keys and South America are separated by a distance of 1393 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Florida Keys to South America one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $46. Users have also found prices from $78 and $82 on Avianca and Arajet, respectively.

  • Can I find deals for flights from Florida Keys to South America that include hotel bookings?

    Yes. In addition to deals on Florida Keys to South America flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to South America?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to South America.

  • Can I find deals for business class flights from Florida Keys to South America?

    Yes. Cheapflights offers flight deals from Florida Keys to South America by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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