$245+ Cheap flights from the United States to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — SCL
Nov 23 — Nov 301
Round-trip
1 adult, Economy
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Find cheap flights from USA to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from USA to SantiagoExplore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:21 pm -
1 stop27h 58m
Tue 11/101:26 am -
1 stop13h 15m
Deal found 10/21![Copa Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:26 pm -
1 stop11h 49m
Fri 12/1110:30 pm -
1 stop14h 29m
Deal found 10/20![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 pm -
2 stops36h 20m
Sat 11/710:45 pm -
1 stop15h 07m
Deal found 10/21![United Airlines logo]()
$506
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop23h 45m
Mon 11/1610:30 pm -
1 stop14h 30m
Deal found 10/21![American Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:59 pm -
1 stop35h 51m
Thu 12/1010:45 pm -
2 stops37h 03m
Deal found 10/21![United Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:57 pm -
2 stops17h 18m
Sat 12/1210:30 pm -
1 stop18h 51m
Deal found 10/21![American Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:00 am -
2 stops45h 50m
Thu 12/310:45 pm -
2 stops24h 52m
Deal found 10/24![United Airlines logo]()
$521
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:36 pm -
1 stop28h 43m
Fri 11/61:02 am -
1 stop12h 47m
Deal found 10/24![Copa Airlines logo]()
$522
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:55 pm -
1 stop29h 27m
Thu 10/293:28 am -
1 stop19h 54m
Deal found 10/19![Copa Airlines logo]()
$524
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:19 pm -
1 stop10h 56m
Sun 12/1310:30 pm -
2 stops17h 13m
Deal found 10/20![American Airlines logo]()
$535
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:10 pm -
1 stop13h 35m
Mon 11/162:10 am -
1 stop20h 25m
Deal found 10/21![Avianca logo]()
$537
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:05 am -
2 stops20h 25m
Tue 11/108:25 pm -
2 stops21h 52m
Deal found 10/22![Delta logo]()
$546
Best flights from USA to SantiagoDiscover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:59 pm -
1 stop35h 51m
Thu 12/1010:45 pm -
2 stops37h 03m
Deal found 10/21![United Airlines logo]()
$514
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:40 pm -
1 stop28h 35m
Mon 11/93:48 am -
1 stop20h 13m
Deal found 10/19![Copa Airlines logo]()
$524
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:15 am -
1 stop19h 25m
Mon 11/911:10 pm -
1 stop23h 46m
Deal found 10/23![Delta logo]()
$546
This LATAM Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:45 pm -
2 stops15h 15m
Thu 12/1011:10 pm -
2 stops19h 30m
Deal found 10/19![LATAM Airlines logo]()
$596
This Avianca deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:30 am -
1 stop21h 15m
Wed 11/187:30 am -
1 stop17h 05m
Deal found 10/20![Avianca logo]()
$710
This Sky Airline deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:50 am -
1 stop17h 35m
Wed 11/187:45 am -
2 stops25h 25m
Deal found 10/20![Sky Airline logo]()
$825
This Expedia deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/116:20 pm -
2 stops34h 05m
Sat 4/1710:55 pm -
2 stops36h 15m
Deal found 10/24![Multiple Airlines logo]()
$883
This Arajet deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/304:45 pm -
1 stop11h 53m
Wed 1/205:00 am -
1 stop12h 15m
Deal found 10/24![Arajet logo]()
$896
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:15 am -
1 stop20h 20m
Thu 11/1211:10 pm -
1 stop16h 32m
Deal found 10/22![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:32 pm -
1 stop17h 18m
Fri 11/610:45 pm -
1 stop17h 42m
Deal found 10/23![United Airlines logo]()
$546
This Copa Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/711:25 am -
1 stop25h 27m
Sat 3/274:06 pm -
1 stop19h 55m
Deal found 10/20![Copa Airlines logo]()
$557
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/54:15 pm -
1 stop13h 25m
Tue 11/1011:50 pm -
1 stop18h 32m
Deal found 10/24![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:45 am -
2 stops25h 05m
Sun 12/1310:45 pm -
2 stops25h 14m
Deal found 10/22![United Airlines logo]()
$550
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/78:28 am -
1 stop28h 24m
Mon 3/2911:58 pm -
1 stop19h 42m
Deal found 10/23![Copa Airlines logo]()
$592
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:00 am -
1 stop21h 40m
Sat 11/711:10 pm -
1 stop16h 34m
Deal found 10/22![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:05 pm -
2 stops34h 45m
Wed 11/1810:45 pm -
2 stops20h 42m
Deal found 10/24![United Airlines logo]()
$550
This Avianca deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:15 am -
1 stop12h 55m
Mon 11/237:30 am -
1 stop17h 05m
Deal found 10/19![Avianca logo]()
$711
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/201:10 pm -
1 stop15h 45m
Wed 1/2711:00 pm -
1 stop17h 03m
Deal found 10/24![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:30 am -
2 stops25h 20m
Fri 11/610:45 pm -
1 stop24h 43m
Deal found 10/23![United Airlines logo]()
$550
This Air Canada deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:55 pm -
2 stops21h 20m
Thu 11/269:55 pm -
2 stops25h 22m
Deal found 10/20![Air Canada logo]()
$1,592
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/279:30 am -
2 stops21h 20m
Sat 10/3110:45 pm -
2 stops17h 47m
Deal found 10/23![United Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/261:20 pm -
1 stop15h 35m
Fri 2/124:45 pm -
1 stop24h 30m
Deal found 10/19![Delta logo]()
$577
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:16 am -
1 stop23h 32m
Thu 11/1912:15 pm -
1 stop14h 45m
Deal found 10/19![Copa Airlines logo]()
$713
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:00 am -
1 stop21h 50m
Mon 12/710:45 pm -
1 stop15h 17m
Deal found 10/23![United Airlines logo]()
$560
This FlightHub deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
2 stops17h 15m
Tue 12/89:45 am -
2 stops19h 10m
Deal found 10/24![LATAM Airlines logo]()
$937
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:10 pm -
2 stops35h 40m
Thu 12/1010:45 pm -
2 stops37h 03m
Deal found 10/23![United Airlines logo]()
$564
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:05 am -
1 stop16h 20m
Wed 11/2511:10 pm -
1 stop23h 46m
Deal found 10/20![Delta logo]()
$647
This Arajet deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/254:38 pm -
1 stop12h 00m
Wed 12/305:00 am -
1 stop32h 25m
Deal found 10/22![Arajet logo]()
$1,063
This Copa Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:15 am -
1 stop23h 31m
Mon 11/161:02 am -
1 stop15h 48m
Deal found 10/23![Copa Airlines logo]()
$806
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:17 pm -
2 stops35h 33m
Tue 11/1710:45 pm -
2 stops23h 32m
Deal found 10/23![United Airlines logo]()
$579
Last-minute flights from USA to SantiagoDiscover last-minute flight deals from USA to Santiago. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Santiago. Data last updated October 24, 2026 and is based on user searches.
This Copa Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:55 pm -
1 stop29h 27m
Thu 10/293:28 am -
1 stop19h 54m
Deal found 10/19![Copa Airlines logo]()
$524
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:59 pm -
1 stop33h 41m
Sat 10/3111:10 pm -
1 stop19h 56m
Deal found 10/23![Delta logo]()
$554
This Copa Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/272:36 pm -
1 stop28h 43m
Fri 11/61:02 am -
1 stop12h 47m
Deal found 10/24![Copa Airlines logo]()
$522
This Copa Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/283:21 pm -
1 stop27h 58m
Tue 11/101:26 am -
1 stop13h 15m
Deal found 10/21![Copa Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:30 pm -
2 stops36h 20m
Sat 11/710:45 pm -
1 stop15h 07m
Deal found 10/21![United Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/15:30 am -
2 stops25h 20m
Wed 11/1110:45 pm -
2 stops19h 05m
Deal found 10/22![United Airlines logo]()
$550
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:05 am -
2 stops20h 25m
Tue 11/108:25 pm -
2 stops21h 52m
Deal found 10/22![Delta logo]()
$546
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:00 am -
1 stop23h 45m
Mon 11/1610:30 pm -
1 stop14h 30m
Deal found 10/21![American Airlines logo]()
$508
This Avianca deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/82:10 pm -
1 stop13h 35m
Mon 11/162:10 am -
1 stop20h 25m
Deal found 10/21![Avianca logo]()
$537
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:45 pm -
2 stops15h 15m
Tue 12/89:45 am -
2 stops16h 55m
Deal found 10/20![LATAM Airlines logo]()
$539
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2612:01 pm -
1 stop19h 24m
Sun 12/1311:15 pm -
1 stop22h 05m
Deal found 10/21![American Airlines logo]()
$502
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:00 am -
2 stops45h 50m
Thu 12/310:45 pm -
2 stops24h 52m
Deal found 10/24![United Airlines logo]()
$521
One-way flights from USA to SantiagoSearch for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This Arajet deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:38 pm -
1 stop12h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Arajet logo]()
$245
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:20 am -
2 stops23h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![United Airlines logo]()
$250
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/132:44 pm -
1 stop16h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![American Airlines logo]()
$253
This LATAM Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
2 stops24h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![LATAM Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/193:31 pm -
2 stops19h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$257
This LATAM Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:20 pm -
2 stops32h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![LATAM Airlines logo]()
$259
This eDestinos deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:35 pm -
1 stop14h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![LATAM Airlines logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:17 pm -
2 stops30h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:50 am -
1 stop24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Sky Airline logo]()
$267
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:17 pm -
1 stop38h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![United Airlines logo]()
$269
This eDestinos deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2912:55 pm -
1 stop12h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Arajet logo]()
$271
This Trip.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/277:30 pm -
1 stop10h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Sky Airline logo]()
$272
Find flight deals from USA to Santiago
Keep the following information in mind while searching for USA to Santiago flight deals. Data was last updated October 24, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $502 (American Airlines) |
One-way from | $245 (Arajet) |
Popular in | December |
Cheapest in | April |
Average price | $873 |
Good round-trip deal | $852 or less |
Good one-way deal | $494 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from the United States to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Thu 11/19
2:50 pm-8:15 pm
1 stop27h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$250
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Fri 11/13
9:10 am-7:40 am
2 stops20h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Tue 12/1
1:00 pm-6:55 am
1 stop15h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Mon 1/4
1:57 pm-9:20 am
2 stops17h 23m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Fri 11/13
1:45 pm-7:40 am
1 stop15h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Sun 1/10
12:26 pm-8:50 am
2 stops18h 24m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Wed 11/4
7:15 am-5:35 am
1 stop20h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Wed 1/13
9:55 am-7:00 am
2 stops19h 05m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
OrlandoSantiago
MCO Orlando - SCL Santiago Arturo Merino Benitez
MCOSCL
Orlando
Tue 11/24
7:00 am-8:50 am
1 stop23h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$288
OrlandoSantiago
MCO Orlando - SCL Santiago Arturo Merino Benitez
MCOSCL
Orlando
Thu 11/26
11:15 am-6:55 am
1 stop17h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$288
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from USA with our price prediction graph.
BOS-SCL
MIA-SCL
DCA-SCL
MCO-SCL
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Santiago
US0-SCL
BOS-SCL
MIA-SCL
DCA-SCL
MCO-SCL
What is the cheapest month to book a flight from USA to Santiago?
Currently, April is the cheapest month in which you can book a flight from USA to Santiago (average of $808). Flying from USA to Santiago in December is currently the most expensive (average of $1,111). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SCL?
Find hourly flight availability from USA to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 24, 2026.
It’s typically best to fly out from USA to Santiago in the morning. Doing so could potentially save you 26% on the flight price compared to flying in the afternoon, which is usually more expensive.
How often are flights from the United States to Santiago delayed?
About 23% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 171 minutes.
What is the most punctual flight time for the United States to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 15% of flights being delayed.
How far ahead should I book a flight from USA to Santiago?
The price you pay for your flight from USA to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from USA to Santiago?
Use this chart to determine the cheapest time to fly round-trip from USA to Santiago. Price data was last updated on October 24, 2026.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for theUnited States to Santiago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santiago trip
Our travel experts
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 24, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Comfort
7.8
Boarding
8.1
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from USA to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for USA to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Santiago by cabin class
Find flights from USA to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Santiago flights
Browse other USA and Santiago flight options. Last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 24, 2026.
USA to Santiago flights
Consider these flights traveling from USA to Santiago.
Top 10 airlines flying from USA to Santiago
Discover the top 10 airlines that operate flights from USA to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$184 | Average$886 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$232 | Average$488 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$742 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$343 | Average$900 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$345 | Average$903 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$380 | Average$927 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$405 | Average$547 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$406 | Average$1,310 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$483 | Average$930 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$798 | Average$924 | FlexibilityNo cancel fee | On-time74% |