$219+ Cheap flights from the United States to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — SCL
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from USA to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from USA to SantiagoExplore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This eDestinos deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:38 pm -
1 stop12h 00m
Mon 11/96:00 am -
1 stop12h 23m
Deal found 9/5![Arajet logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$451
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 am -
1 stop17h 35m
Thu 11/198:35 pm -
1 stop12h 35m
Deal found 9/3![Sky Airline logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:50 am -
1 stop10h 45m
Mon 12/78:35 pm -
1 stop12h 35m
Deal found 9/3![Sky Airline logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:50 am -
1 stop17h 35m
Sun 11/158:35 pm -
1 stop12h 35m
Deal found 9/7![Sky Airline logo]()
$460
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$462
This Booking.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:18 pm -
1 stop12h 20m
Sat 11/149:25 am -
1 stop12h 17m
Deal found 9/3![Arajet logo]()
$464
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:50 am -
1 stop10h 45m
Tue 11/108:35 pm -
1 stop12h 35m
Deal found 9/7![Sky Airline logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sat 11/148:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Wed 11/118:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 am -
1 stop10h 46m
Fri 11/138:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$469
Best flights from USA to SantiagoDiscover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Arajet deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:55 pm -
1 stop12h 40m
Mon 11/26:00 am -
1 stop12h 23m
Deal found 9/7![Arajet logo]()
$622
This Copa Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:22 am -
1 stop17h 17m
Mon 11/212:15 pm -
1 stop14h 55m
Deal found 9/4![Copa Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/303:00 pm -
1 stop13h 40m
Wed 3/310:15 am -
1 stop14h 50m
Deal found 9/2![Delta logo]()
$676
This KAYAK deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:50 am -
2 stops53h 26m
Sat 11/146:35 pm -
2 stops38h 35m
Deal found 9/7![Sky Airline logo]()
$762
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/178:25 am -
1 stop22h 25m
Wed 2/2410:45 pm -
1 stop14h 52m
Deal found 9/5![United Airlines logo]()
$765
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1012:55 pm -
2 stops37h 50m
Sun 1/174:15 pm -
1 stop23h 15m
Deal found 9/3![Avianca logo]()
$771
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:15 am -
1 stop11h 26m
Tue 10/68:33 pm -
2 stops17h 06m
Deal found 9/7![Multiple Airlines logo]()
$938
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:15 am -
1 stop19h 40m
Fri 11/2011:55 pm -
1 stop18h 07m
Deal found 9/3![LATAM Airlines logo]()
$964
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:15 am -
1 stop17h 21m
Mon 11/1612:15 pm -
1 stop14h 55m
Deal found 9/5![Copa Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/283:00 pm -
1 stop13h 40m
Wed 3/311:10 pm -
1 stop13h 22m
Deal found 9/2![Delta logo]()
$676
This Copa Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/292:22 am -
1 stop13h 57m
Mon 11/161:22 am -
1 stop15h 28m
Deal found 9/2![Copa Airlines logo]()
$649
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:25 pm -
Nonstop10h 30m
Tue 12/111:50 pm -
Nonstop10h 35m
Deal found 9/5![Delta logo]()
$697
This Arajet deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/164:18 pm -
1 stop12h 20m
Thu 12/3110:00 am -
1 stop12h 32m
Deal found 9/3![Arajet logo]()
$777
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:12 am -
1 stop20h 38m
Mon 11/210:45 pm -
1 stop14h 40m
Deal found 9/2![United Airlines logo]()
$785
This SmartFares deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/23:05 pm -
1 stop12h 40m
Fri 10/94:20 pm -
2 stops26h 25m
Deal found 9/2![Avianca logo]()
$787
This Copa Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:25 am -
1 stop20h 57m
Mon 11/212:15 pm -
1 stop13h 18m
Deal found 9/3![Copa Airlines logo]()
$658
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:25 pm -
Nonstop10h 30m
Thu 11/2611:50 pm -
Nonstop10h 35m
Deal found 9/5![Delta logo]()
$697
This Arajet deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/35:30 am -
1 stop23h 08m
Thu 3/1810:00 am -
1 stop14h 30m
Deal found 9/6![Arajet logo]()
$787
This KAYAK deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/229:50 am -
2 stops51h 50m
Wed 1/207:40 am -
2 stops49h 30m
Deal found 9/7![Sky Airline logo]()
$871
This Copa Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/222:25 am -
1 stop20h 14m
Mon 10/2612:23 pm -
1 stop16h 57m
Deal found 9/6![Copa Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/812:30 pm -
2 stops18h 20m
Sun 12/2010:45 pm -
1 stop24h 54m
Deal found 9/2![United Airlines logo]()
$811
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:50 pm -
Nonstop10h 35m
Tue 10/2011:55 pm -
Nonstop10h 45m
Deal found 9/6![Delta logo]()
$701
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:16 am -
1 stop21h 03m
Tue 11/1712:15 pm -
1 stop13h 18m
Deal found 9/5![Copa Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/117:35 am -
1 stop23h 15m
Wed 1/2010:45 pm -
1 stop17h 40m
Deal found 9/4![United Airlines logo]()
$811
This Arajet deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:30 am -
1 stop23h 08m
Wed 1/205:00 am -
1 stop20h 30m
Deal found 9/6![Arajet logo]()
$816
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/181:30 pm -
1 stop14h 05m
Tue 12/18:25 pm -
1 stop13h 50m
Deal found 9/4![Delta logo]()
$701
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:35 pm -
2 stops18h 50m
Tue 10/63:15 am -
2 stops17h 39m
Deal found 9/2![Multiple Airlines logo]()
$1,086
This Arajet deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/65:30 am -
1 stop19h 20m
Fri 2/125:00 am -
1 stop20h 30m
Deal found 9/3![Arajet logo]()
$821
This Copa Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:25 am -
1 stop17h 07m
Wed 10/283:28 am -
1 stop22h 09m
Deal found 9/2![Copa Airlines logo]()
$686
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:22 pm -
1 stop14h 33m
Fri 10/168:20 am -
1 stop14h 05m
Deal found 9/5![Delta logo]()
$705
Last-minute flights from USA to SantiagoDiscover last-minute flight deals from USA to Santiago. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Santiago. Data last updated September 7, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:55 pm -
1 stop12h 40m
Fri 10/3012:55 am -
1 stop12h 30m
Deal found 9/3![Arajet logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$451
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sat 11/148:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$467
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Wed 11/118:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$468
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sun 11/151:33 pm -
1 stop19h 37m
Deal found 9/4![Sky Airline logo]()
$474
This CheapOair deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:50 am -
1 stop10h 46m
Sat 10/311:34 pm -
1 stop19h 36m
Deal found 9/4![Sky Airline logo]()
$476
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:50 am -
1 stop10h 46m
Thu 11/128:35 pm -
1 stop12h 35m
Deal found 9/7![Sky Airline logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 am -
1 stop10h 46m
Fri 11/138:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2810:50 am -
1 stop10h 46m
Sun 11/18:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$471
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2910:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$461
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:50 am -
1 stop10h 46m
Sat 11/79:25 am -
1 stop12h 17m
Deal found 9/7![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:50 am -
1 stop10h 46m
Tue 11/38:35 pm -
1 stop12h 35m
Deal found 9/6![Sky Airline logo]()
$470
One-way flights from USA to SantiagoSearch for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:27 am -
2 stops41h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$219
This Expedia deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2911:00 am -
1 stop15h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Arajet logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2512:00 pm -
1 stop15h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Arajet logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:00 am -
1 stop18h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Arajet logo]()
$249
This Mytrip deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:50 am -
2 stops26h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Sky Airline logo]()
$250
This Mytrip deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:50 am -
2 stops26h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Sky Airline logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:12 pm -
2 stops28h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$252
This eDestinos deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/283:02 pm -
1 stop11h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Arajet logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 am -
2 stops19h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:50 am -
1 stop10h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Sky Airline logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:50 am -
2 stops26h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Sky Airline logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:20 pm -
1 stop19h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Sky Airline logo]()
$260
Find flight deals from USA to Santiago
Keep the following information in mind while searching for USA to Santiago flight deals. Data was last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $442 (eDestinos) |
One-way from | $219 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $748 |
Good round-trip deal | $779 or less |
Good one-way deal | $449 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from the United States to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhiladelphiaSantiago
PHL Philadelphia - SCL Santiago Arturo Merino Benitez
PHLSCL
Philadelphia
Tue 11/10
11:27 am-6:38 am
2 stops41h 11m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$219
AtlantaSantiago
ATL Atlanta Hartsfield-Jackson - SCL Santiago Arturo Merino Benitez
ATLSCL
Atlanta Hartsfield-Jackson
Mon 11/2
7:47 pm-10:35 pm
2 stops24h 48m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$272
AtlantaSantiago
ATL Atlanta Hartsfield-Jackson - SCL Santiago Arturo Merino Benitez
ATLSCL
Atlanta Hartsfield-Jackson
Sat 10/3
12:19 pm-4:55 am
2 stops39h 36m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$288
NewarkSantiago
EWR Newark - SCL Santiago Arturo Merino Benitez
EWRSCL
Newark
Tue 10/20
12:00 pm-3:35 am
1 stop14h 35m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$289
NewarkSantiago
EWR Newark - SCL Santiago Arturo Merino Benitez
EWRSCL
Newark
Tue 12/29
11:00 am-3:35 am
1 stop14h 35m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$303
AtlantaSantiago
ATL Atlanta Hartsfield-Jackson - SCL Santiago Arturo Merino Benitez
ATLSCL
Atlanta Hartsfield-Jackson
Wed 9/30
3:30 pm-3:56 am
2 stops35h 26m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$305
Washington, D.C.Santiago
IAD Washington, D.C. Dulles Intl - SCL Santiago Arturo Merino Benitez
IADSCL
Washington, D.C. Dulles Intl
Thu 10/22
9:06 pm-10:36 pm
3 stops48h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$314
NewarkSantiago
EWR Newark - SCL Santiago Arturo Merino Benitez
EWRSCL
Newark
Sun 11/8
11:00 am-4:55 am
1 stop15h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$328
NewarkSantiago
EWR Newark - SCL Santiago Arturo Merino Benitez
EWRSCL
Newark
Tue 9/29
12:00 pm-3:35 am
1 stop14h 35m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$334
AtlantaSantiago
ATL Atlanta Hartsfield-Jackson - SCL Santiago Arturo Merino Benitez
ATLSCL
Atlanta Hartsfield-Jackson
Mon 10/5
8:59 pm-3:56 am
2 stops29h 57m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$334
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from USA with our price prediction graph.
MIA-SCL
LAX-SCL
LGA-SCL
IAD-SCL
DFW-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Santiago
US0-SCL
MIA-SCL
LAX-SCL
LGA-SCL
IAD-SCL
What is the cheapest month to book a flight from USA to Santiago?
Currently, November is the cheapest month in which you can book a flight from USA to Santiago (average of $793). Flying from USA to Santiago in December is currently the most expensive (average of $1,064). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SCL?
Find hourly flight availability from USA to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 7, 2026.
It’s typically best to fly out from USA to Santiago in the morning. Doing so could potentially save you 22% on the flight price compared to flying at noon, which is usually more expensive.
How often are flights from the United States to Santiago delayed?
About 25% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 173 minutes.
What is the most punctual flight time for the United States to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 16% of flights being delayed.
How far ahead should I book a flight from USA to Santiago?
The price you pay for your flight from USA to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 31 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
The best insider tips for theUnited States to Santiago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santiago trip
Our travel experts
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 7, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Boarding
8.1
Comfort
7.8
Crew
8.5
Overall
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from USA to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for USA to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Santiago by cabin class
Find flights from USA to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Santiago flights
Browse other USA and Santiago flight options. Last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
USA to Santiago flights
Consider these flights traveling from USA to Santiago.
Top 10 airlines flying from USA to Santiago
Discover the top 10 airlines that operate flights from USA to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$184 | Average$714 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$199 | Average$828 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$232 | Average$468 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$287 | Average$663 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$328 | Average$864 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$380 | Average$925 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$406 | Average$1,263 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$415 | Average$553 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$483 | Average$904 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$919 | Average$1,298 | FlexibilityNo cancel fee | On-timeN/A |