$260+ Cheap flights from the United States to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — SCL
Aug 12 — Aug 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from USA to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from USA to Santiago
Cheapest
Best
Last-minute
One-way
Cheapest flights from USA to SantiagoExplore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Mytrip deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:12 pm
MIA
- SCL
2 stops20h 23m
Multiple Airlines
Mon 9/712:35 pm
SCL
- MIA
1 stop29h 25m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$511
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Sat 8/298:20 pm
SCL
- MIA
1 stop20h 40m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$512
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/114:02 pm
MIA
- SCL
1 stop11h 53m
Arajet
Wed 10/145:00 am
SCL
- MIA
1 stop12h 10m
Arajet
Deal found 7/11![Arajet logo]()
$513
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:12 pm
MIA
- SCL
2 stops34h 59m
Multiple Airlines
Wed 9/305:00 am
SCL
- MIA
1 stop12h 10m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$514
This Trip.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Mon 10/56:53 am
SCL
- MIA
1 stop26h 17m
Sky Airline
Deal found 7/12![Sky Airline logo]()
$516
This FlightHub deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/259:50 am
MIA
- SCL
1 stop10h 45m
Sky Airline
Thu 12/101:30 pm
SCL
- MIA
1 stop19h 40m
Sky Airline
Deal found 7/10![Sky Airline logo]()
$519
This Gotogate deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Mon 9/712:35 pm
SCL
- MIA
1 stop29h 25m
Sky Airline
Deal found 7/10![Sky Airline logo]()
$521
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:20 pm
MIA
- SCL
1 stop19h 15m
Multiple Airlines
Mon 8/3111:35 am
SCL
- MIA
2 stops24h 50m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$523
This oojo deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:20 pm
MIA
- SCL
2 stops16h 45m
Sky Airline
Mon 9/219:20 pm
SCL
- MIA
1 stop20h 40m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1410:45 pm
MIA
- SCL
Nonstop7h 10m
Multiple Airlines
Fri 10/25:00 am
SCL
- MIA
1 stop11h 48m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$526
This Booking.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:20 pm
MIA
- SCL
1 stop26h 45m
Multiple Airlines
Fri 10/25:00 am
SCL
- MIA
1 stop12h 10m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$527
This Trip.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:05 am
IAD
- SCL
2 stops36h 21m
Multiple Airlines
Tue 9/16:40 am
SCL
- IAD
1 stop22h 40m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$537
Best flights from USA to SantiagoDiscover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Sky Airline deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sky Airline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:20 pm
MIA
- SCL
1 stop11h 15m
Sky Airline
Tue 12/18:35 pm
SCL
- MIA
1 stop12h 35m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$539
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:55 pm
JFK
- SCL
2 stops18h 10m
Delta
Tue 8/2510:55 pm
SCL
- JFK
Nonstop10h 45m
Delta
Deal found 7/11![Delta logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:34 pm
IAD
- SCL
1 stop26h 58m
Copa Airlines
Sat 10/312:23 pm
SCL
- IAD
1 stop16h 57m
Copa Airlines
Deal found 7/9![Copa Airlines logo]()
$645
This LATAM Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:00 am
LGA
- SCL
2 stops27h 20m
Multiple Airlines
Sat 8/224:30 pm
SCL
- LGA
2 stops30h 29m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$650
This Arajet deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:55 pm
MIA
- SCL
1 stop12h 40m
Arajet
Mon 10/56:00 am
SCL
- MIA
1 stop12h 23m
Arajet
Deal found 7/12![Arajet logo]()
$660
This FlightHub deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:20 pm
BOS
- SCL
1 stop15h 35m
LATAM Airlines
Mon 9/711:55 pm
SCL
- BOS
1 stop15h 47m
LATAM Airlines
Deal found 7/12![LATAM Airlines logo]()
$679
This Avianca deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:25 pm
DFW
- SCL
2 stops18h 50m
Avianca
Fri 10/304:25 pm
SCL
- DFW
2 stops22h 00m
Avianca
Deal found 7/12![Avianca logo]()
$694
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:51 pm
EWR
- SCL
1 stop27h 09m
United Airlines
Sat 8/294:14 am
SCL
- EWR
2 stops31h 39m
United Airlines
Deal found 7/9![United Airlines logo]()
$828
This oojo deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Sat 9/261:35 am
SCL
- MIA
2 stops16h 25m
Sky Airline
Deal found 7/12![Sky Airline logo]()
$618
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:10 pm
JFK
- SCL
1 stop14h 25m
Delta
Tue 8/256:45 pm
SCL
- JFK
1 stop26h 25m
Delta
Deal found 7/11![Delta logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/164:34 pm
IAD
- SCL
1 stop30h 48m
Copa Airlines
Sun 9/205:14 am
SCL
- IAD
1 stop24h 06m
Copa Airlines
Deal found 7/13![Copa Airlines logo]()
$645
This LATAM Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/207:00 am
LGA
- SCL
2 stops30h 35m
Multiple Airlines
Tue 9/811:05 pm
SCL
- LGA
2 stops24h 41m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$650
This Justfly.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/77:20 am
BOS
- SCL
2 stops30h 05m
LATAM Airlines
Mon 9/2111:55 pm
SCL
- BOS
1 stop15h 47m
LATAM Airlines
Deal found 7/13![LATAM Airlines logo]()
$688
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:10 pm
JFK
- SCL
1 stop18h 05m
Delta
Wed 8/1910:55 pm
SCL
- JFK
Nonstop10h 45m
Delta
Deal found 7/12![Delta logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/72:25 am
IAD
- SCL
1 stop26h 45m
Copa Airlines
Wed 10/712:23 pm
SCL
- IAD
1 stop16h 57m
Copa Airlines
Deal found 7/11![Copa Airlines logo]()
$645
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:21 am
IAD
- SCL
2 stops16h 25m
Multiple Airlines
Sat 10/35:15 am
SCL
- IAD
1 stop20h 17m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$651
This oojo deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/111:55 pm
DFW
- SCL
2 stops37h 50m
Avianca
Tue 8/186:40 am
SCL
- DFW
2 stops30h 35m
Avianca
Deal found 7/12![Avianca logo]()
$735
This CheapOair deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:45 pm
MIA
- SCL
Nonstop7h 10m
LATAM Airlines
Tue 9/298:30 am
SCL
- MIA
Nonstop13h 45m
LATAM Airlines
Deal found 7/8![LATAM Airlines logo]()
$700
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:10 pm
JFK
- SCL
1 stop15h 45m
Delta
Thu 8/2010:55 pm
SCL
- JFK
Nonstop10h 45m
Delta
Deal found 7/8![Delta logo]()
$640
This Avianca deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/143:05 pm
DFW
- SCL
1 stop12h 40m
Avianca
Tue 9/151:30 am
SCL
- DFW
1 stop14h 10m
Avianca
Deal found 7/12![Avianca logo]()
$739
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:17 pm
EWR
- SCL
1 stop13h 57m
United Airlines
Fri 8/282:14 am
SCL
- EWR
2 stops33h 39m
United Airlines
Deal found 7/9![United Airlines logo]()
$828
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:51 am
LAX
- SCL
1 stop22h 09m
Copa Airlines
Mon 9/285:14 am
SCL
- LAX
1 stop21h 44m
Copa Airlines
Deal found 7/9![Copa Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:50 pm
JFK
- SCL
Nonstop10h 35m
Delta
Sun 8/308:40 pm
SCL
- JFK
1 stop15h 19m
Delta
Deal found 7/10![Delta logo]()
$646
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/227:40 pm
EWR
- SCL
2 stops27h 03m
United Airlines
Fri 8/2812:43 am
SCL
- EWR
2 stops35h 10m
United Airlines
Deal found 7/12![United Airlines logo]()
$833
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:51 am
LAX
- SCL
1 stop17h 48m
Copa Airlines
Tue 9/221:06 am
SCL
- LAX
1 stop25h 52m
Copa Airlines
Deal found 7/9![Copa Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:50 pm
JFK
- SCL
Nonstop10h 35m
Delta
Tue 9/111:00 pm
SCL
- JFK
1 stop15h 30m
Delta
Deal found 7/8![Delta logo]()
$646
This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/278:47 am
BOS
- SCL
1 stop14h 35m
Copa Airlines
Tue 10/63:57 am
SCL
- BOS
1 stop20h 05m
Copa Airlines
Deal found 7/8![Copa Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:59 pm
JFK
- SCL
1 stop17h 26m
Delta
Sun 8/308:40 pm
SCL
- JFK
1 stop13h 25m
Delta
Deal found 7/9![Delta logo]()
$646
This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:19 am
LAX
- SCL
1 stop21h 41m
Copa Airlines
Thu 8/132:14 am
SCL
- LAX
1 stop23h 44m
Copa Airlines
Deal found 7/8![Copa Airlines logo]()
$703
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/237:50 pm
JFK
- SCL
Nonstop10h 35m
Delta
Sun 8/308:40 pm
SCL
- JFK
1 stop13h 25m
Delta
Deal found 7/9![Delta logo]()
$646
Last-minute flights from USA to SantiagoDiscover last-minute flight deals from USA to Santiago. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Santiago. Data last updated July 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:12 pm
MIA
- SCL
2 stops20h 23m
Multiple Airlines
Tue 8/258:20 pm
SCL
- MIA
1 stop20h 40m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$526
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Sat 8/298:20 pm
SCL
- MIA
1 stop20h 40m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$512
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:12 pm
MIA
- SCL
2 stops27h 53m
Multiple Airlines
Tue 8/258:20 pm
SCL
- MIA
1 stop20h 40m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$532
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Mon 8/315:00 am
SCL
- MIA
1 stop12h 00m
Sky Airline
Deal found 7/10![Sky Airline logo]()
$539
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:52 pm
IAD
- SCL
2 stops32h 58m
Multiple Airlines
Mon 8/242:56 am
SCL
- IAD
1 stop21h 37m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$585
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:20 pm
MIA
- SCL
1 stop19h 15m
Multiple Airlines
Mon 8/3111:35 am
SCL
- MIA
2 stops24h 50m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$523
This oojo deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Fri 8/2812:55 am
SCL
- MIA
2 stops16h 05m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$524
This Trip.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:05 am
IAD
- SCL
2 stops36h 21m
Multiple Airlines
Tue 9/16:40 am
SCL
- IAD
1 stop22h 40m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$537
This Mytrip deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:12 pm
MIA
- SCL
2 stops27h 53m
Multiple Airlines
Fri 9/1812:55 am
SCL
- MIA
1 stop12h 30m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$540
This Mytrip deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:12 pm
MIA
- SCL
2 stops27h 53m
Multiple Airlines
Mon 9/712:35 pm
SCL
- MIA
1 stop29h 25m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$534
This Mytrip deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:12 pm
MIA
- SCL
2 stops20h 23m
Multiple Airlines
Mon 9/712:35 pm
SCL
- MIA
1 stop29h 25m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$511
This Gotogate deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Mon 9/712:35 pm
SCL
- MIA
1 stop29h 25m
Sky Airline
Deal found 7/10![Sky Airline logo]()
$521
One-way flights from USA to SantiagoSearch for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:29 pm
LGA
- SCL
2 stops30h 27m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/184:16 pm
DFW
- SCL
3 stops33h 44m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$264
This oojo deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:20 pm
MIA
- SCL
1 stop19h 15m
Sky Airline
Deal found 7/9![Sky Airline logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:05 am
IAD
- SCL
2 stops35h 38m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:24 am
BWI
- SCL
2 stops20h 36m
Multiple Airlines
Deal found 7/12![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/211:30 am
EWR
- SCL
2 stops32h 02m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:12 pm
MIA
- SCL
2 stops20h 23m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:30 am
EWR
- SCL
2 stops17h 40m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/278:29 pm
LGA
- SCL
2 stops29h 21m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:16 pm
DFW
- SCL
3 stops32h 34m
Multiple Airlines
Deal found 7/13![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:16 pm
DFW
- SCL
3 stops32h 30m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/93:55 pm
DFW
- SCL
3 stops32h 51m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$276
Find flight deals from USA to Santiago
Keep the following information in mind while searching for USA to Santiago flight deals. Data was last updated July 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $511 (Mytrip) |
One-way from | $260 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $921 |
Good round-trip deal | $831 or less |
Good one-way deal | $444 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from the United States to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MiamiSantiago
MIA - SCL
MIASCL
Miami
Tue 9/1
6:20 pm-5:35 am
1 stop11h 15m
Santiago Arturo Merino Benitez
Tue 12/1
8:35 pm-7:10 am
1 stop12h 35m
$539
MiamiSantiago
MIA - SCL
MIASCL
Miami
Fri 9/18
6:20 pm-2:35 pm
1 stop19h 15m
Santiago Arturo Merino Benitez
Sat 9/26
1:35 am-5:00 pm
2 stops16h 25m
$618
New YorkSantiago
JFK - SCL
JFKSCL
New York John F Kennedy Intl
Thu 8/20
7:55 pm-2:05 pm
2 stops18h 10m
Santiago Arturo Merino Benitez
Tue 8/25
10:55 pm-9:40 am
Nonstop10h 45m
$640
New YorkSantiago
JFK - SCL
JFKSCL
New York John F Kennedy Intl
Sun 8/16
3:10 pm-5:35 am
1 stop14h 25m
Santiago Arturo Merino Benitez
Tue 8/25
6:45 pm-9:10 pm
1 stop26h 25m
$640
New YorkSantiago
JFK - SCL
JFKSCL
New York John F Kennedy Intl
Tue 8/11
1:10 pm-7:15 am
1 stop18h 05m
Santiago Arturo Merino Benitez
Wed 8/19
10:55 pm-9:40 am
Nonstop10h 45m
$640
New YorkSantiago
JFK - SCL
JFKSCL
New York John F Kennedy Intl
Sun 8/16
3:10 pm-6:55 am
1 stop15h 45m
Santiago Arturo Merino Benitez
Thu 8/20
10:55 pm-9:40 am
Nonstop10h 45m
$640
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Mon 9/28
4:34 pm-8:32 pm
1 stop26h 58m
Santiago Arturo Merino Benitez
Sat 10/3
12:23 pm-4:20 am
1 stop16h 57m
$645
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Wed 9/16
4:34 pm-12:22 am
1 stop30h 48m
Santiago Arturo Merino Benitez
Sun 9/20
5:14 am-4:20 am
1 stop24h 06m
$645
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Mon 9/7
2:25 am-6:10 am
1 stop26h 45m
Santiago Arturo Merino Benitez
Wed 10/7
12:23 pm-4:20 am
1 stop16h 57m
$645
New YorkSantiago
JFK - SCL
JFKSCL
New York John F Kennedy Intl
Wed 8/19
7:50 pm-6:25 am
Nonstop10h 35m
Santiago Arturo Merino Benitez
Sun 8/30
8:40 pm-11:59 am
1 stop15h 19m
$646
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from USA with our price prediction graph.
MIA-SCL
IAD-SCL
LGA-SCL
DFW-SCL
BWI-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Santiago
US0-SCL
MIA-SCL
IAD-SCL
LGA-SCL
DFW-SCL
What is the cheapest month to book a flight from USA to Santiago?
Currently, October is the cheapest month in which you can book a flight from USA to Santiago (average of $714). Flying from USA to Santiago in December is currently the most expensive (average of $1,041). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SCL?
Find hourly flight availability from USA to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 13, 2026.
It’s typically best to fly out from USA to Santiago in the morning. Doing so could potentially save you 27% on the flight price compared to flying at noon, which is usually more expensive.
How often are flights from the United States to Santiago delayed?
About 24% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 178 minutes.
What is the most punctual flight time for the United States to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 15% of flights being delayed.
How far ahead should I book a flight from USA to Santiago?
The price you pay for your flight from USA to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 35 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
The best insider tips for theUnited States to Santiago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santiago trip
Our travel experts
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 13, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Entertainment
7.8
Overall
7.8
Boarding
8.1
Food
7.2
Crew
8.5
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from USA to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Santiago flight routes
Top destinations
Alternative routes for USA to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Santiago by cabin class
Find flights from USA to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Santiago flights
Browse other USA and Santiago flight options. Last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 13, 2026.
USA to Santiago flights
Consider these flights traveling from USA to Santiago.
Top 9 airlines flying from USA to Santiago
Discover the top 9 airlines that operate flights from USA to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$197 | Average$488 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$224 | Average$675 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$287 | Average$672 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$406 | Average$968 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$437 | Average$561 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$494 | Average$857 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$494 | Average$951 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$532 | Average$888 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$543 | Average$967 | FlexibilityNo cancel fee | On-timeN/A |