$323+ Cheap flights from Denver (DEN) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santiago
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Cheapest flights from Denver to SantiagoExplore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This Expedia deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:36 am -
1 stop17h 04m
Thu 12/179:50 pm -
1 stop24h 52m
Deal found 9/2![LATAM Airlines logo]()
$693
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:40 am -
1 stop21h 10m
Fri 12/1110:45 pm -
1 stop19h 40m
Deal found 9/6![United Airlines logo]()
$743
This LATAM Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
2 stops19h 00m
Fri 12/118:40 am -
2 stops19h 23m
Deal found 9/6![LATAM Airlines logo]()
$748
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:38 pm -
1 stop16h 47m
Sat 12/1211:45 pm -
1 stop16h 35m
Deal found 9/6![American Airlines logo]()
$754
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 pm -
2 stops19h 00m
Mon 11/911:55 pm -
1 stop15h 47m
Deal found 9/3![LATAM Airlines logo]()
$766
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 pm -
2 stops19h 00m
Wed 11/411:10 pm -
2 stops18h 02m
Deal found 9/3![LATAM Airlines logo]()
$771
Best flights from Denver to SantiagoDiscover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/33:10 pm -
2 stops19h 50m
Wed 2/178:25 pm -
2 stops21h 51m
Deal found 9/3![Delta logo]()
$743
This United Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:25 pm -
1 stop33h 25m
Wed 2/310:45 pm -
1 stop28h 42m
Deal found 9/3![United Airlines logo]()
$761
This FlightHub deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:10 am -
2 stops17h 25m
Wed 11/2511:10 pm -
2 stops18h 05m
Deal found 9/2![LATAM Airlines logo]()
$794
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/21:35 pm -
2 stops21h 25m
Thu 3/2511:10 pm -
1 stop24h 13m
Deal found 9/7![Delta logo]()
$743
This LATAM Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
2 stops17h 35m
Fri 12/1111:10 pm -
2 stops23h 32m
Deal found 9/4![LATAM Airlines logo]()
$801
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/66:30 am -
1 stop19h 05m
Sun 3/2111:55 pm -
1 stop21h 15m
Deal found 9/6![Delta logo]()
$743
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/287:05 am -
1 stop19h 35m
Mon 3/2211:10 pm -
1 stop18h 06m
Deal found 9/7![Delta logo]()
$743
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/31:35 pm -
2 stops21h 25m
Thu 3/2511:10 pm -
1 stop18h 06m
Deal found 9/7![Delta logo]()
$743
This Delta deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/13:10 pm -
2 stops19h 50m
Tue 3/1610:50 pm -
1 stop24h 44m
Deal found 9/4![Delta logo]()
$743
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:05 am -
1 stop19h 30m
Tue 11/37:30 am -
2 stops19h 02m
Deal found 9/3![Delta logo]()
$815
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:00 am -
2 stops22h 30m
Tue 11/38:40 am -
2 stops17h 52m
Deal found 9/3![Delta logo]()
$815
Last-minute flights from Denver to SantiagoDiscover last-minute flight deals from Denver to Santiago. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santiago. Data last updated September 7, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:05 am -
1 stop19h 30m
Sun 11/811:55 pm -
1 stop15h 47m
Deal found 9/3![LATAM Airlines logo]()
$829
This Mytrip deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:53 pm -
2 stops29h 43m
Tue 10/278:55 pm -
1 stop16h 40m
Deal found 9/5![Multiple Airlines logo]()
$796
This Delta deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:00 pm -
2 stops19h 00m
Tue 11/38:25 pm -
2 stops20h 47m
Deal found 9/3![Delta logo]()
$815
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 pm -
2 stops19h 00m
Mon 11/911:55 pm -
1 stop15h 47m
Deal found 9/3![LATAM Airlines logo]()
$766
This FlightHub deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 pm -
2 stops19h 00m
Wed 11/411:10 pm -
2 stops18h 02m
Deal found 9/3![LATAM Airlines logo]()
$771
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 pm -
1 stop18h 36m
Sat 11/145:07 am -
1 stop15h 55m
Deal found 9/3![Copa Airlines logo]()
$798
This Copa Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 pm -
1 stop22h 39m
Wed 11/412:15 pm -
1 stop32h 47m
Deal found 9/3![Copa Airlines logo]()
$803
This Copa Airlines deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 pm -
1 stop22h 39m
Sun 11/81:02 am -
1 stop20h 00m
Deal found 9/3![Copa Airlines logo]()
$831
This Copa Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:43 pm -
1 stop22h 39m
Sun 11/1512:15 pm -
1 stop32h 47m
Deal found 9/5![Copa Airlines logo]()
$853
One-way flights from Denver to SantiagoSearch for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2212:28 pm -
2 stops27h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1812:28 pm -
2 stops36h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$376
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:00 pm -
2 stops31h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Air Canada logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 9/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:55 pm -
3 stops53h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/3![Multiple Airlines logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:40 am -
2 stops17h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/2![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:28 pm -
3 stops29h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$484
This Kiwi.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:25 pm -
2 stops21h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Multiple Airlines logo]()
$496
This Air Canada deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/171:30 pm -
1 stop18h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/6![Air Canada logo]()
$502
Find flight deals from Denver to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $681 (Copa Airlines) |
One-way from | $323 (Kiwi.com) |
Popular in | July |
Cheapest in | June |
Average price | $939 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Fri 1/22
12:28 pm-7:58 pm
2 stops27h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$323
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Wed 10/7
10:56 am-10:36 pm
3 stops32h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$449
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sun 11/29
12:28 pm-9:48 pm
3 stops29h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$484
Quickest round-trip
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Mon 1/18
1:30 pm-12:15 pm
1 stop18h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$502
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sun 1/17
1:30 pm-12:15 pm
1 stop18h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$502
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Thu 10/15
7:05 am-5:35 am
1 stop19h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$515
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sun 1/17
12:59 am-5:03 am
3 stops24h 04m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$531
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Fri 12/18
12:28 pm-12:40 pm
2 stops20h 12m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$553
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Wed 2/3
3:10 pm-3:00 pm
2 stops19h 50m
Santiago Arturo Merino Benitez
Wed 2/17
8:25 pm-2:16 pm
2 stops21h 51m
$743
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Tue 3/2
1:35 pm-3:00 pm
2 stops21h 25m
Santiago Arturo Merino Benitez
Thu 3/25
11:10 pm-8:23 pm
1 stop24h 13m
$743
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Denver to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santiago
How far ahead should I book a flight from Denver to Santiago?
The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Santiago?
Currently, June is the cheapest month in which you can book a flight from Denver to Santiago (average of $755). Flying from Denver to Santiago in July is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Denver to Santiago?
Airfare is below average for this route at the moment.
Denver to Santiago flights typically cost between $735 and $1,145 in February.The cheapest round-trip price found within the last 5 days was $681 on Copa Airlines (Feb 3-Feb 17).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 7, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andLATAM Airlines from Denver to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Comfort
7.8
Boarding
8.1
Overall
7.8
Food
7.2
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Denver to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Denver to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Santiago flights
Browse other Denver and Santiago flight options. Last updated on September 7, 2026.
Other flights from Denver
Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Top 5 airlines flying from Denver to Santiago
Discover the top 5 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$544 | Average$872 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$544 | Average$843 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$552 | Average$923 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$563 | Average$882 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$593 | Average$893 | FlexibilityNo cancel fee | On-time71% |