$292+ Cheap flights from Denver (DEN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santiago
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Best
Last-minute
One-way
Cheapest flights from Denver to SantiagoExplore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:49 pm
DEN
- SCL
1 stop24h 59m
Copa Airlines
Wed 11/1812:15 pm
SCL
- DEN
1 stop32h 47m
Copa Airlines
Deal found 7/24![Copa Airlines logo]()
$605
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am
DEN
- SCL
1 stop23h 00m
American Airlines
Wed 11/1810:15 pm
SCL
- DEN
1 stop25h 26m
American Airlines
Deal found 7/25![American Airlines logo]()
$617
This Copa Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:49 pm
DEN
- SCL
1 stop22h 30m
Copa Airlines
Wed 12/212:20 pm
SCL
- DEN
1 stop32h 50m
Copa Airlines
Deal found 7/25![Copa Airlines logo]()
$618
This Copa Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/79:49 pm
DEN
- SCL
1 stop27h 57m
Copa Airlines
Tue 11/171:02 am
SCL
- DEN
1 stop20h 00m
Copa Airlines
Deal found 7/26![Copa Airlines logo]()
$628
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:36 pm
DEN
- SCL
1 stop16h 24m
American Airlines
Mon 12/1411:45 pm
SCL
- DEN
1 stop20h 03m
American Airlines
Deal found 7/24![American Airlines logo]()
$630
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1710:40 am
DEN
- SCL
2 stops16h 15m
LATAM Airlines
Tue 12/159:50 pm
SCL
- DEN
1 stop24h 24m
LATAM Airlines
Deal found 7/27![LATAM Airlines logo]()
$631
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:05 am
DEN
- SCL
2 stops19h 50m
Delta
Wed 11/188:13 am
SCL
- DEN
2 stops20h 10m
Delta
Deal found 7/24![Delta logo]()
$643
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:00 am
DEN
- SCL
2 stops18h 55m
Delta
Tue 12/111:10 pm
SCL
- DEN
2 stops23h 04m
Delta
Deal found 7/27![Delta logo]()
$648
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 pm
DEN
- SCL
1 stop32h 20m
United Airlines
Sun 11/110:45 pm
SCL
- DEN
1 stop17h 22m
United Airlines
Deal found 7/27![United Airlines logo]()
$652
Best flights from Denver to SantiagoDiscover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This Copa Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:50 pm
DEN
- SCL
1 stop25h 53m
Copa Airlines
Wed 12/93:48 am
SCL
- DEN
1 stop17h 22m
Copa Airlines
Deal found 7/26![Copa Airlines logo]()
$618
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:05 am
DEN
- SCL
2 stops20h 55m
Delta
Sat 10/248:40 pm
SCL
- DEN
1 stop15h 53m
Delta
Deal found 7/25![Delta logo]()
$765
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/147:50 am
DEN
- SCL
1 stop21h 00m
United Airlines
Wed 1/2010:45 pm
SCL
- DEN
1 stop28h 42m
United Airlines
Deal found 7/27![United Airlines logo]()
$911
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:15 am
DEN
- SCL
1 stop22h 00m
Delta
Wed 9/238:40 pm
SCL
- DEN
1 stop21h 11m
Delta
Deal found 7/28![Delta logo]()
$765
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:00 am
DEN
- SCL
1 stop23h 15m
Delta
Sat 10/248:40 pm
SCL
- DEN
1 stop15h 56m
Delta
Deal found 7/25![Delta logo]()
$765
This Delta deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
DEN
- SCL
1 stop23h 15m
Delta
Fri 11/278:13 am
SCL
- DEN
2 stops20h 10m
Delta
Deal found 7/25![Delta logo]()
$807
This Delta deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:05 am
DEN
- SCL
2 stops20h 50m
Delta
Sun 11/811:55 pm
SCL
- DEN
2 stops19h 20m
Delta
Deal found 7/24![Delta logo]()
$812
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
DEN
- SCL
1 stop23h 15m
Delta
Tue 8/1810:55 pm
SCL
- DEN
1 stop25h 49m
Delta
Deal found 7/27![Delta logo]()
$965
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/912:50 am
DEN
- SCL
2 stops16h 55m
Delta
Tue 8/1810:55 pm
SCL
- DEN
1 stop25h 49m
Delta
Deal found 7/26![Delta logo]()
$970
Last-minute flights from Denver to SantiagoDiscover last-minute flight deals from Denver to Santiago. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santiago. Data last updated July 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:25 pm
DEN
- SCL
1 stop16h 00m
American Airlines
Tue 11/1710:15 pm
SCL
- DEN
1 stop17h 25m
American Airlines
Deal found 7/28![American Airlines logo]()
$799
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:00 am
DEN
- SCL
2 stops17h 50m
Multiple Airlines
Thu 8/2711:00 pm
SCL
- DEN
1 stop35h 23m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$801
This Justfly.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/241:15 pm
DEN
- SCL
2 stops15h 40m
LATAM Airlines
Mon 8/3111:25 pm
SCL
- DEN
1 stop20h 53m
LATAM Airlines
Deal found 7/25![LATAM Airlines logo]()
$800
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:15 pm
DEN
- SCL
2 stops15h 40m
LATAM Airlines
Tue 9/111:00 pm
SCL
- DEN
2 stops20h 57m
LATAM Airlines
Deal found 7/26![LATAM Airlines logo]()
$782
This FlightHub deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:15 pm
DEN
- SCL
2 stops15h 40m
LATAM Airlines
Mon 8/3111:25 pm
SCL
- DEN
1 stop20h 53m
LATAM Airlines
Deal found 7/24![LATAM Airlines logo]()
$791
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:59 pm
DEN
- SCL
2 stops23h 51m
Multiple Airlines
Tue 9/111:00 pm
SCL
- DEN
1 stop35h 23m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$792
This Justfly.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:15 pm
DEN
- SCL
2 stops15h 40m
LATAM Airlines
Fri 9/411:25 pm
SCL
- DEN
1 stop15h 24m
LATAM Airlines
Deal found 7/24![LATAM Airlines logo]()
$807
One-way flights from Denver to SantiagoSearch for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:06 pm
DEN
- SCL
3 stops50h 44m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:06 pm
DEN
- SCL
3 stops50h 44m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:43 am
DEN
- SCL
3 stops58h 00m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:31 am
DEN
- SCL
3 stops40h 29m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am
DEN
- SCL
3 stops58h 32m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$320
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1811:59 pm
DEN
- SCL
2 stops27h 15m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:25 am
DEN
- SCL
2 stops36h 23m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$330
Find flight deals from Denver to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $605 (Copa Airlines) |
One-way from | $292 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $1,130 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Wed 12/2
9:50 pm-3:43 am
1 stop25h 53m
Santiago Arturo Merino Benitez
Wed 12/9
3:48 am-5:10 pm
1 stop17h 22m
$618
Quickest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Wed 10/14
7:05 am-7:00 am
2 stops20h 55m
Santiago Arturo Merino Benitez
Sat 10/24
8:40 pm-9:33 am
1 stop15h 53m
$765
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sun 9/20
7:15 am-8:15 am
1 stop22h 00m
Santiago Arturo Merino Benitez
Wed 9/23
8:40 pm-2:51 pm
1 stop21h 11m
$765
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 10/19
6:00 am-8:15 am
1 stop23h 15m
Santiago Arturo Merino Benitez
Sat 10/24
8:40 pm-9:36 am
1 stop15h 56m
$765
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 10/1
6:00 am-8:15 am
1 stop23h 15m
Santiago Arturo Merino Benitez
Fri 11/27
8:13 am-12:23 am
2 stops20h 10m
$807
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 10/15
7:05 am-6:55 am
2 stops20h 50m
Santiago Arturo Merino Benitez
Sun 11/8
11:55 pm-3:15 pm
2 stops19h 20m
$812
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 1/14
7:50 am-8:50 am
1 stop21h 00m
Santiago Arturo Merino Benitez
Wed 1/20
10:45 pm-11:27 pm
1 stop28h 42m
$911
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Tue 8/11
6:00 am-7:15 am
1 stop23h 15m
Santiago Arturo Merino Benitez
Tue 8/18
10:55 pm-10:44 pm
1 stop25h 49m
$965
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sun 8/9
12:50 am-7:45 pm
2 stops16h 55m
Santiago Arturo Merino Benitez
Tue 8/18
10:55 pm-10:44 pm
1 stop25h 49m
$970
Cheapest one-way
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Tue 9/8
7:00 am-8:32 pm
3 stops58h 32m
$320
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Denver to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santiago
How far ahead should I book a flight from Denver to Santiago?
The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Santiago?
Currently, September is the cheapest month in which you can book a flight from Denver to Santiago (average of $743). Flying from Denver to Santiago in July is currently the most expensive (average of $1,130). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Denver to Santiago?
Airfare is below average for this route at the moment.
Denver to Santiago flights typically cost between $726 and $1,072 in November.The cheapest round-trip price found within the last 5 days was $605 on Copa Airlines (Nov 8-Nov 18).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated July 28, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andLATAM Airlines from Denver to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Denver and Santiago flights
Browse other Denver and Santiago flight options. Last updated on July 28, 2026.
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Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
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Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Top 5 airlines flying from Denver to Santiago
Discover the top 5 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$544 | Average$754 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$544 | Average$801 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$551 | Average$852 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$552 | Average$841 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$593 | Average$884 | FlexibilityNo cancel fee | On-time71% |