$328+ Cheap flights from Denver (DEN) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/4. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from Denver to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santiago
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Cheapest flights from Denver to SantiagoExplore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:40 am -
1 stop21h 10m
Fri 12/1110:45 pm -
1 stop19h 40m
Deal found 9/8![United Airlines logo]()
$693
This LATAM Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:00 am -
2 stops19h 00m
Fri 12/118:40 am -
2 stops19h 23m
Deal found 9/8![LATAM Airlines logo]()
$740
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:25 am -
1 stop19h 10m
Fri 11/2011:55 pm -
1 stop15h 47m
Deal found 9/10![LATAM Airlines logo]()
$749
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/19:55 pm -
3 stops28h 43m
Sat 12/129:55 pm -
1 stop16h 40m
Deal found 9/9![Multiple Airlines logo]()
$750
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop23h 25m
Sat 12/1211:45 pm -
1 stop19h 48m
Deal found 9/9![American Airlines logo]()
$754
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1012:36 pm -
1 stop16h 24m
Sat 12/1910:15 pm -
2 stops19h 15m
Deal found 9/8![American Airlines logo]()
$789
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:45 am -
2 stops17h 00m
Sun 12/2010:15 pm -
1 stop17h 30m
Deal found 9/7![American Airlines logo]()
$796
Best flights from Denver to SantiagoDiscover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:40 am -
1 stop21h 10m
Fri 12/1110:45 pm -
1 stop19h 40m
Deal found 9/8![United Airlines logo]()
$693
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:49 pm -
1 stop24h 59m
Wed 11/1812:15 pm -
1 stop32h 47m
Deal found 9/11![Copa Airlines logo]()
$803
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:25 am -
1 stop19h 10m
Mon 11/2311:55 pm -
1 stop22h 57m
Deal found 9/8![Delta logo]()
$815
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/612:57 am -
2 stops26h 33m
Fri 12/117:30 am -
2 stops19h 44m
Deal found 9/11![LATAM Airlines logo]()
$835
This Justfly.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:05 am -
1 stop19h 30m
Sun 11/88:40 am -
2 stops19h 13m
Deal found 9/10![LATAM Airlines logo]()
$849
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
2 stops30h 00m
Thu 11/128:40 am -
2 stops18h 35m
Deal found 9/7![Delta logo]()
$857
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:20 pm -
1 stop12h 30m
Sat 10/3110:45 pm -
1 stop23h 25m
Deal found 9/10![United Airlines logo]()
$870
Last-minute flights from Denver to SantiagoDiscover last-minute flight deals from Denver to Santiago. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santiago. Data last updated September 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:56 pm -
2 stops31h 30m
Wed 10/711:55 pm -
1 stop15h 32m
Deal found 9/7![Multiple Airlines logo]()
$881
This Justfly.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:05 am -
1 stop19h 30m
Sun 11/88:40 am -
2 stops19h 13m
Deal found 9/10![LATAM Airlines logo]()
$849
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:53 pm -
2 stops29h 43m
Thu 10/298:55 pm -
1 stop16h 40m
Deal found 9/9![Multiple Airlines logo]()
$861
This Mytrip deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/221:53 pm -
2 stops29h 43m
Thu 10/298:55 pm -
1 stop22h 55m
Deal found 9/7![Multiple Airlines logo]()
$873
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:25 pm -
1 stop35h 25m
Fri 10/309:45 pm -
1 stop16h 37m
Deal found 9/8![United Airlines logo]()
$880
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:56 pm -
2 stops30h 59m
Sat 10/3111:10 pm -
1 stop37h 19m
Deal found 9/10![Multiple Airlines logo]()
$799
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/244:20 pm -
1 stop12h 30m
Sat 10/3110:45 pm -
1 stop23h 25m
Deal found 9/10![United Airlines logo]()
$870
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:20 pm -
2 stops16h 25m
Sat 10/3110:15 pm -
2 stops18h 05m
Deal found 9/10![American Airlines logo]()
$875
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:40 am -
1 stop21h 10m
Mon 11/210:45 pm -
1 stop19h 43m
Deal found 9/11![United Airlines logo]()
$890
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:00 am -
2 stops30h 00m
Thu 11/128:40 am -
2 stops18h 35m
Deal found 9/7![Delta logo]()
$857
One-way flights from Denver to SantiagoSearch for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:43 am -
3 stops38h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:57 pm -
3 stops47h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:57 pm -
3 stops48h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/239:26 pm -
3 stops45h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:28 pm -
2 stops20h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2412:28 pm -
2 stops30h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:57 pm -
3 stops47h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$378
Find flight deals from Denver to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 12, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $681 (Copa Airlines) |
One-way from | $328 (Kiwi.com) |
Popular in | July |
Cheapest in | June |
Average price | $939 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Mon 11/23
9:26 pm-10:35 pm
3 stops45h 09m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$350
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Tue 11/24
12:28 pm-10:35 pm
2 stops30h 07m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$372
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sat 11/14
6:56 pm-5:25 am
2 stops30h 29m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$373
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Fri 11/13
6:57 pm-10:35 pm
3 stops47h 38m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$398
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sat 11/14
1:26 pm-9:15 pm
1 stop27h 49m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$513
Quickest round-trip
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Thu 10/15
7:05 am-5:35 am
1 stop19h 30m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-8:00 pm
Nonstop0h 00m
$536
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Mon 12/7
7:40 am-8:50 am
1 stop21h 10m
Santiago Arturo Merino Benitez
Fri 12/11
10:45 pm-2:25 pm
1 stop19h 40m
$693
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sun 11/8
9:49 pm-2:48 am
1 stop24h 59m
Santiago Arturo Merino Benitez
Wed 11/18
12:15 pm-5:02 pm
1 stop32h 47m
$803
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Mon 11/16
6:25 am-5:35 am
1 stop19h 10m
Santiago Arturo Merino Benitez
Mon 11/23
11:55 pm-6:52 pm
1 stop22h 57m
$815
DenverSantiago
DEN Denver Intl - SCL Santiago Arturo Merino Benitez
DENSCL
Denver Intl
Sun 12/6
12:57 am-7:30 am
2 stops26h 33m
Santiago Arturo Merino Benitez
Fri 12/11
7:30 am-11:14 pm
2 stops19h 44m
$835
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Denver to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santiago
How far ahead should I book a flight from Denver to Santiago?
The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 68 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Santiago?
Currently, June is the cheapest month in which you can book a flight from Denver to Santiago (average of $755). Flying from Denver to Santiago in July is currently the most expensive (average of $1,133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Denver to Santiago?
Airfare is below average for this route at the moment.
Denver to Santiago flights typically cost between $735 and $1,145 in March.The cheapest round-trip price found within the last 5 days was $681 on Copa Airlines (Mar 1-Mar 16).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 12, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andLATAM Airlines from Denver to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Boarding
8.1
Overall
7.8
Reviews
1 / 20
4.0
OkayJennifer,Sep 2026
ORD - LGA
Related info for your journey
Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Denver to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Denver to Santiago by cabin class
Find flights from Denver to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Denver and Santiago flights
Browse other Denver and Santiago flight options. Last updated on September 12, 2026.
Other flights from Denver
Browse through other flights departing from Denver. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
Top 5 airlines flying from Denver to Santiago
Discover the top 5 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$544 | Average$867 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$544 | Average$856 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$552 | Average$923 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$563 | Average$880 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$593 | Average$898 | FlexibilityNo cancel fee | On-time71% |