HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$622+ Cheap flights from Denver (DEN) to Santiago (SCL)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
may. 25 — jun. 11
dom. 5/25
dom. 6/1
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Denver to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Denver Intl to Santiago Arturo Merino Benitez are usually found in April or May, booked 66 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Denver to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated mayo 20, 2025.

Most accurate provider

AranGrant
3 stars

Most trusted provider

AranGrant
3 stars

Round-trip from

$648
(American Airlines)

Popular in

December

Cheapest in

April

Average price

$753
Provider with most accurate pricing for Denver Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Denver Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2025
Search Deals

Find flight deals from Denver to Santiago

Cheapest flights from Denver to Santiago
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on mayo 20, 2025.

This Copa Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/1510:42 pmDEN - SCL
1 stop22h 22mCopa Airlines
lun. 9/225:10 amSCL - DEN
1 stop15h 57mCopa Airlines
Deal found 5/18$622
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/192:05 pmDEN - SCL
1 stop15h 00mAmerican Airlines
mié. 9/179:55 pmSCL - DEN
1 stop15h 55mAmerican Airlines
Deal found 5/19$634
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/512:32 pmDEN - SCL
1 stop15h 28mDelta
lun. 9/2211:05 pmSCL - DEN
1 stop26h 53mDelta
Deal found 5/20$746
This LATAM Airlines deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/1212:00 pmDEN - SCL
1 stop16h 00mLATAM Airlines
jue. 9/259:40 pmSCL - DEN
1 stop23h 22mLATAM Airlines
Deal found 5/18$754
This LATAM Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/1612:59 amDEN - SCL
2 stops25h 46mMultiple Airlines
mar. 6/2411:00 amSCL - DEN
1 stop25h 24mMultiple Airlines
Deal found 5/19$766

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 20, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Denver

Fly to

Santiago

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 9/15

10:42 pm-12:04 am

1 stop22h 22m

Santiago Arturo Merino Benitez

lun. 9/22

5:10 am-6:07 pm

1 stop15h 57m

$622

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

mar. 8/19

2:05 pm-7:05 am

1 stop15h 00m

Santiago Arturo Merino Benitez

mié. 9/17

9:55 pm-10:50 am

1 stop15h 55m

$634

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

vie. 9/5

12:32 pm-6:00 am

1 stop15h 28m

Santiago Arturo Merino Benitez

lun. 9/22

11:05 pm-10:58 pm

1 stop26h 53m

$746

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

vie. 9/12

12:00 pm-7:00 am

1 stop16h 00m

Santiago Arturo Merino Benitez

jue. 9/25

9:40 pm-6:02 pm

1 stop23h 22m

$754

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 6/16

12:59 am-4:45 am

2 stops25h 46m

Santiago Arturo Merino Benitez

mar. 6/24

11:00 am-10:24 am

1 stop25h 24m

$766

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 8/11

10:42 pm-10:44 pm

1 stop22h 02m

$1,505

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 8/11

4:35 pm-4:25 pm

2 stops21h 50m

$1,812

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

dom. 8/10

12:59 am-7:00 am

1 stop28h 01m

$2,729

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

lun. 8/11

5:33 pm-8:38 pm

3 stops49h 05m

$7,783

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/19

Compare providers for flights from Denver to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in May.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*2 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago

How far ahead should I book a flight from Denver to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santiago. Price data was last updated on May 16, 2025.

The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 66 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santiago?

Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SCL?

Find hourly flight availability from Denver to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated mayo 20, 2025.

When flying from Denver to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight in the morning.

What is the cheapest day to fly from Denver to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Denver to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Denver to Santiago flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated mayo 20, 2025.
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,951 reviews
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,780 reviews
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,428 reviews
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.0
Good
9,375 reviews
Delta
8.0
Very good
7,951 reviews

Boarding

8.2

Overall

8.0

Crew

8.5

Comfort

7.9

Food

7.3

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Denver to Santiago round-trip?

    Currently priced at $648, American Airlines will fly you from Denver to Santiago and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Copa Airlines and Delta - these airlines can fly you to your destination from $656 and $754, respectively. American Airlines is currently priced 23% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Denver to Santiago one-way?

    To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $1,505. LATAM Airlines flights start at $1,812 while deals on Delta start at $2,729 one-way.

  • Can I find deals for flights from Denver to Santiago that include hotel bookings?

    Yes. In addition to deals on Denver to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago.

  • Can I find deals for business class flights from Denver to Santiago?

    Yes. Cheapflights offers flight deals from Denver to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Denver to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Denver to Punta Arenas flights
Denver to La Serena flights
Denver to Easter Island flights
Denver to Temuco flights
Grand Junction to Santiago flights
Montrose to Santiago flights

Top 6 airlines flying from Denver to Santiago

Discover the top 6 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated mayo 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$592Average$832FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$601Average$886FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$621Average$739FlexibilityNo cancel feeOn-time70%
DeltaCheapest$752Average$877FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$752Average$894FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$794Average$1,152FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.