$339+ Cheap flights from Denver (DEN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/24. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Denver to SantiagoExplore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:49 pm
DEN
- SCL
1 stop27h 57m
Copa Airlines
Tue 11/173:19 am
SCL
- DEN
1 stop17h 43m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$557
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:50 am
DEN
- SCL
1 stop20h 10m
American Airlines
Sat 11/2110:15 pm
SCL
- DEN
1 stop17h 46m
American Airlines
Deal found 6/6![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:27 pm
DEN
- SCL
2 stops16h 33m
American Airlines
Mon 11/2310:15 pm
SCL
- DEN
2 stops23h 34m
American Airlines
Deal found 6/7![American Airlines logo]()
$574
This Copa Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:49 pm
DEN
- SCL
1 stop25h 49m
Copa Airlines
Sun 11/223:19 am
SCL
- DEN
1 stop17h 43m
Copa Airlines
Deal found 6/5![Copa Airlines logo]()
$580
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/112:25 pm
DEN
- SCL
2 stops17h 25m
American Airlines
Sun 10/119:30 pm
SCL
- DEN
1 stop27h 31m
American Airlines
Deal found 6/7![American Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:25 pm
DEN
- SCL
2 stops17h 25m
American Airlines
Sat 9/269:30 pm
SCL
- DEN
2 stops19h 09m
American Airlines
Deal found 6/7![American Airlines logo]()
$585
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:00 pm
DEN
- SCL
1 stop14h 15m
Delta
Tue 10/208:40 pm
SCL
- DEN
1 stop24h 24m
Delta
Deal found 6/4![Delta logo]()
$593
This LATAM Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:59 am
DEN
- SCL
2 stops33h 36m
LATAM Airlines
Sun 11/84:00 pm
SCL
- DEN
2 stops30h 04m
LATAM Airlines
Deal found 6/5![LATAM Airlines logo]()
$594
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am
DEN
- SCL
2 stops21h 55m
Delta
Tue 10/208:40 pm
SCL
- DEN
1 stop15h 55m
Delta
Deal found 6/4![Delta logo]()
$598
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am
DEN
- SCL
2 stops28h 35m
Delta
Thu 10/2911:10 pm
SCL
- DEN
1 stop15h 44m
Delta
Deal found 6/6![Delta logo]()
$601
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2712:50 am
DEN
- SCL
1 stop28h 25m
Delta
Mon 10/198:40 pm
SCL
- DEN
1 stop24h 24m
Delta
Deal found 6/4![Delta logo]()
$602
Best flights from Denver to SantiagoDiscover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:43 pm
DEN
- SCL
1 stop22h 39m
Copa Airlines
Fri 10/231:44 am
SCL
- DEN
1 stop19h 27m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$580
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:00 am
DEN
- SCL
1 stop23h 15m
Delta
Thu 10/158:40 pm
SCL
- DEN
1 stop24h 24m
Delta
Deal found 6/4![Delta logo]()
$593
This LATAM Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:05 am
DEN
- SCL
2 stops27h 20m
LATAM Airlines
Sun 11/111:25 pm
SCL
- DEN
1 stop22h 45m
LATAM Airlines
Deal found 6/8![LATAM Airlines logo]()
$593
This Copa Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:43 pm
DEN
- SCL
1 stop26h 13m
Copa Airlines
Wed 10/712:23 pm
SCL
- DEN
1 stop32h 48m
Copa Airlines
Deal found 6/4![Copa Airlines logo]()
$580
This Delta deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:15 pm
DEN
- SCL
1 stop16h 00m
Delta
Sun 10/118:40 pm
SCL
- DEN
1 stop20h 36m
Delta
Deal found 6/7![Delta logo]()
$593
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:49 pm
DEN
- SCL
1 stop25h 49m
Copa Airlines
Mon 11/235:07 am
SCL
- DEN
1 stop15h 55m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$580
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:05 am
DEN
- SCL
1 stop23h 10m
Delta
Mon 10/198:40 pm
SCL
- DEN
1 stop18h 14m
Delta
Deal found 6/5![Delta logo]()
$593
This Copa Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:43 pm
DEN
- SCL
1 stop26h 13m
Copa Airlines
Sun 9/2712:22 pm
SCL
- DEN
1 stop32h 49m
Copa Airlines
Deal found 6/7![Copa Airlines logo]()
$580
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:05 am
DEN
- SCL
1 stop22h 10m
Delta
Thu 10/2911:10 pm
SCL
- DEN
1 stop15h 44m
Delta
Deal found 6/6![Delta logo]()
$709
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am
DEN
- SCL
1 stop20h 55m
Delta
Sat 10/2411:05 pm
SCL
- DEN
2 stops21h 59m
Delta
Deal found 6/4![Delta logo]()
$709
Last-minute flights from Denver to SantiagoDiscover last-minute flight deals from Denver to Santiago. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santiago. Data last updated June 9, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:58 am
DEN
- SCL
2 stops16h 37m
LATAM Airlines
Thu 7/911:25 pm
SCL
- DEN
1 stop20h 53m
LATAM Airlines
Deal found 6/5![LATAM Airlines logo]()
$852
This FlightHub deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/912:29 pm
DEN
- SCL
1 stop15h 06m
LATAM Airlines
Tue 7/1411:00 pm
SCL
- DEN
2 stops20h 56m
LATAM Airlines
Deal found 6/5![LATAM Airlines logo]()
$812
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:39 pm
DEN
- SCL
2 stops16h 21m
American Airlines
Mon 8/39:00 pm
SCL
- DEN
1 stop16h 19m
American Airlines
Deal found 6/5![American Airlines logo]()
$775
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:05 am
DEN
- SCL
2 stops20h 30m
Delta
Wed 7/2911:25 pm
SCL
- DEN
1 stop20h 53m
Delta
Deal found 6/4![Delta logo]()
$830
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/179:39 am
DEN
- SCL
1 stop19h 36m
Delta
Wed 7/2210:55 pm
SCL
- DEN
1 stop21h 50m
Delta
Deal found 6/8![Delta logo]()
$865
This eDestinos deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:10 pm
DEN
- SCL
1 stop16h 05m
LATAM Airlines
Wed 7/2911:25 pm
SCL
- DEN
1 stop20h 53m
LATAM Airlines
Deal found 6/6![LATAM Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:45 am
DEN
- SCL
1 stop23h 30m
Delta
Thu 7/308:40 pm
SCL
- DEN
1 stop18h 20m
Delta
Deal found 6/8![Delta logo]()
$825
This Delta deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:29 pm
DEN
- SCL
1 stop15h 06m
Delta
Sun 8/910:55 pm
SCL
- DEN
1 stop25h 50m
Delta
Deal found 6/4![Delta logo]()
$715
This LATAM Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:31 am
DEN
- SCL
1 stop20h 04m
LATAM Airlines
Sun 8/911:05 pm
SCL
- DEN
2 stops27h 31m
LATAM Airlines
Deal found 6/4![LATAM Airlines logo]()
$716
One-way flights from Denver to SantiagoSearch for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:00 am
DEN
- SCL
3 stops43h 00m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:42 pm
DEN
- SCL
3 stops48h 34m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:42 pm
DEN
- SCL
3 stops24h 38m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$350
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
DEN
- SCL
3 stops35h 32m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:44 pm
DEN
- SCL
3 stops51h 32m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:41 pm
DEN
- SCL
3 stops33h 39m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:00 am
DEN
- SCL
3 stops38h 16m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am
DEN
- SCL
3 stops42h 51m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$397
Find flight deals from Denver to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $557 (Copa Airlines) |
One-way from | $339 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $755 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 10/19
10:43 pm-12:22 am
1 stop22h 39m
Santiago Arturo Merino Benitez
Fri 10/23
1:44 am-6:11 pm
1 stop19h 27m
$580
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sat 9/26
10:43 pm-3:56 am
1 stop26h 13m
Santiago Arturo Merino Benitez
Wed 10/7
12:23 pm-6:11 pm
1 stop32h 48m
$580
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sat 11/14
9:49 pm-3:38 am
1 stop25h 49m
Santiago Arturo Merino Benitez
Mon 11/23
5:07 am-5:02 pm
1 stop15h 55m
$580
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sat 9/12
10:43 pm-3:56 am
1 stop26h 13m
Santiago Arturo Merino Benitez
Sun 9/27
12:22 pm-6:11 pm
1 stop32h 49m
$580
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sun 10/4
6:00 am-8:15 am
1 stop23h 15m
Santiago Arturo Merino Benitez
Thu 10/15
8:40 pm-6:04 pm
1 stop24h 24m
$593
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 10/29
7:05 am-1:25 pm
2 stops27h 20m
Santiago Arturo Merino Benitez
Sun 11/1
11:25 pm-6:10 pm
1 stop22h 45m
$593
Quickest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 10/1
1:15 pm-8:15 am
1 stop16h 00m
Santiago Arturo Merino Benitez
Sun 10/11
8:40 pm-2:16 pm
1 stop20h 36m
$593
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sun 10/11
6:05 am-8:15 am
1 stop23h 10m
Santiago Arturo Merino Benitez
Mon 10/19
8:40 pm-11:54 am
1 stop18h 14m
$593
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 10/19
7:05 am-8:15 am
1 stop22h 10m
Santiago Arturo Merino Benitez
Thu 10/29
11:10 pm-11:54 am
1 stop15h 44m
$709
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 10/19
6:30 am-6:25 am
1 stop20h 55m
Santiago Arturo Merino Benitez
Sat 10/24
11:05 pm-6:04 pm
2 stops21h 59m
$709
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Denver to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santiago
How far ahead should I book a flight from Denver to Santiago?
The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 70 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Santiago?
Currently, September is the cheapest month in which you can book a flight from Denver to Santiago (average of $677). Flying from Denver to Santiago in July is currently the most expensive (average of $921). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Denver to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 9, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andLATAM Airlines from Denver to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Overall
7.9
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
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Top 5 airlines flying from Denver to Santiago
Discover the top 5 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$544 | Average$745 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$544 | Average$755 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$551 | Average$840 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$552 | Average$746 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$593 | Average$847 | FlexibilityNo cancel fee | On-time71% |