$403+ Cheap flights from Portland (PDX) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
May 25 — Jun 11
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Santiago with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Santiago
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Best
Last-minute
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Cheapest flights from Portland to SantiagoExplore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 25, 2026.
This Air Canada deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:10 pm
PDX
- SCL
2 stops35h 05m
Air Canada
Tue 1/267:55 pm
SCL
- PDX
2 stops27h 35m
Air Canada
Deal found 4/21![Air Canada logo]()
$930
This Air Canada deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:10 pm
PDX
- SCL
2 stops35h 05m
Air Canada
Sun 12/67:25 am
SCL
- PDX
2 stops40h 05m
Air Canada
Deal found 4/24![Air Canada logo]()
$931
This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:00 am
PDX
- SCL
1 stop20h 25m
LATAM Airlines
Wed 8/2611:25 pm
SCL
- PDX
1 stop15h 48m
LATAM Airlines
Deal found 4/21![LATAM Airlines logo]()
$1,037
This eDestinos deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:45 am
PDX
- SCL
1 stop15h 50m
Multiple Airlines
Wed 7/1511:25 pm
SCL
- PDX
1 stop20h 22m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$1,042
This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:01 am
PDX
- SCL
1 stop20h 24m
LATAM Airlines
Wed 7/1511:25 pm
SCL
- PDX
1 stop15h 55m
LATAM Airlines
Deal found 4/21![LATAM Airlines logo]()
$1,044
This eDestinos deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:00 am
PDX
- SCL
2 stops19h 25m
Multiple Airlines
Mon 7/2010:55 pm
SCL
- PDX
1 stop24h 38m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$1,051
This oojo deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/165:37 pm
PDX
- SCL
1 stop32h 58m
Multiple Airlines
Wed 6/245:40 am
SCL
- PDX
2 stops30h 41m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$1,052
This LATAM Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
PDX
- SCL
1 stop20h 25m
LATAM Airlines
Thu 9/1011:25 pm
SCL
- PDX
1 stop16h 48m
LATAM Airlines
Deal found 4/22![LATAM Airlines logo]()
$1,060
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:01 am
PDX
- SCL
1 stop20h 24m
LATAM Airlines
Wed 6/2411:25 pm
SCL
- PDX
1 stop16h 00m
LATAM Airlines
Deal found 4/22![LATAM Airlines logo]()
$1,062
This FlightHub deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:30 am
PDX
- SCL
2 stops19h 20m
LATAM Airlines
Tue 8/2511:00 pm
SCL
- PDX
2 stops22h 55m
LATAM Airlines
Deal found 4/21![LATAM Airlines logo]()
$1,066
This oojo deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:45 pm
PDX
- SCL
2 stops28h 50m
Multiple Airlines
Thu 7/1610:55 pm
SCL
- PDX
1 stop24h 38m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$1,068
Best flights from Portland to SantiagoDiscover carefully curated flight deals from Portland to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
Discover carefully curated flight deals from Portland to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 25, 2026.
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:10 pm
PDX
- SCL
2 stops21h 15m
LATAM Airlines
Tue 8/2512:40 am
SCL
- PDX
2 stops21h 15m
LATAM Airlines
Deal found 4/22![LATAM Airlines logo]()
$1,066
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:30 pm
PDX
- SCL
3 stops29h 50m
Multiple Airlines
Mon 9/217:40 am
SCL
- PDX
3 stops35h 11m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$1,174
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:13 am
PDX
- SCL
2 stops18h 46m
United Airlines
Tue 9/1512:22 pm
SCL
- PDX
2 stops38h 29m
United Airlines
Deal found 4/21![United Airlines logo]()
$1,278
This FlightHub deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:00 am
PDX
- SCL
1 stop20h 25m
LATAM Airlines
Tue 9/1511:00 pm
SCL
- PDX
2 stops23h 55m
LATAM Airlines
Deal found 4/25![LATAM Airlines logo]()
$1,093
This Expedia deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
PDX
- SCL
2 stops18h 50m
Multiple Airlines
Thu 9/1012:25 am
SCL
- PDX
1 stop15h 48m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$1,186
This FlightHub deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:45 pm
PDX
- SCL
2 stops18h 00m
LATAM Airlines
Mon 10/2611:05 pm
SCL
- PDX
2 stops24h 03m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$1,118
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:13 am
PDX
- SCL
2 stops16h 43m
United Airlines
Tue 9/153:27 am
SCL
- PDX
2 stops23h 24m
United Airlines
Deal found 4/21![United Airlines logo]()
$1,278
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/145:35 pm
PDX
- SCL
2 stops58h 20m
Multiple Airlines
Mon 9/2112:25 am
SCL
- PDX
1 stop15h 48m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$1,260
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:13 am
PDX
- SCL
2 stops16h 43m
United Airlines
Mon 10/269:45 pm
SCL
- PDX
3 stops24h 46m
United Airlines
Deal found 4/25![United Airlines logo]()
$1,281
Last-minute flights from Portland to SantiagoDiscover last-minute flight deals from Portland to Santiago. Data last updated April 25, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Santiago. Data last updated April 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:31 pm
PDX
- SCL
1 stop33h 04m
Multiple Airlines
Thu 5/1411:17 am
SCL
- PDX
2 stops27h 33m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$1,308
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:15 pm
PDX
- SCL
3 stops26h 30m
Multiple Airlines
Thu 5/213:20 pm
SCL
- PDX
3 stops32h 36m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$1,274
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2211:15 pm
PDX
- SCL
3 stops36h 00m
Multiple Airlines
Fri 5/298:30 am
SCL
- PDX
2 stops32h 20m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$1,327
This FlightHub deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:55 am
PDX
- SCL
1 stop20h 30m
LATAM Airlines
Fri 5/2911:25 pm
SCL
- PDX
1 stop16h 11m
LATAM Airlines
Deal found 4/22![LATAM Airlines logo]()
$1,371
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:10 am
PDX
- SCL
2 stops22h 55m
American Airlines
Fri 5/299:00 pm
SCL
- PDX
2 stops22h 42m
American Airlines
Deal found 4/22![American Airlines logo]()
$1,400
One-way flights from Portland to SantiagoSearch for one-way flight options from Portland to Santiago. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
Search for one-way flight options from Portland to Santiago. Find affordable one-way fares based on user searches. Data last updated April 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:46 pm
PDX
- SCL
3 stops46h 37m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$403
This eDestinos deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:48 am
PDX
- SCL
3 stops56h 38m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:00 am
PDX
- SCL
2 stops22h 05m
American Airlines
Deal found 4/24![American Airlines logo]()
$869
This SmartFares deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 am
PDX
- SCL
1 stop20h 25m
LATAM Airlines
Deal found 4/24![LATAM Airlines logo]()
$873
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:35 pm
PDX
- SCL
3 stops50h 50m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$1,236
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:38 pm
PDX
- SCL
3 stops48h 42m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$1,428
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:05 pm
PDX
- SCL
1 stop28h 20m
Delta
Deal found 4/21![Delta logo]()
$2,529
Find flight deals from Portland to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $1,037 (FlightHub) |
One-way from | $403 (Kiwi.com) |
Popular in | June |
Cheapest in | January |
Average price | $1,228 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Wed 8/12
5:10 pm-5:25 pm
2 stops21h 15m
Santiago Arturo Merino Benitez
Tue 8/25
12:40 am-6:55 pm
2 stops21h 15m
$1,066
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Tue 9/1
7:00 am-6:25 am
1 stop20h 25m
Santiago Arturo Merino Benitez
Tue 9/15
11:00 pm-6:55 pm
2 stops23h 55m
$1,093
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Wed 9/23
9:45 pm-7:45 pm
2 stops18h 00m
Santiago Arturo Merino Benitez
Mon 10/26
11:05 pm-7:08 pm
2 stops24h 03m
$1,118
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Mon 9/14
2:30 pm-12:20 am
3 stops29h 50m
Santiago Arturo Merino Benitez
Mon 9/21
7:40 am-2:51 pm
3 stops35h 11m
$1,174
Quickest round-trip
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Wed 8/26
7:00 am-4:50 am
2 stops18h 50m
Santiago Arturo Merino Benitez
Thu 9/10
12:25 am-12:13 pm
1 stop15h 48m
$1,186
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Mon 9/14
5:35 pm-7:55 am
2 stops58h 20m
Santiago Arturo Merino Benitez
Mon 9/21
12:25 am-12:13 pm
1 stop15h 48m
$1,260
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Tue 9/8
7:13 am-5:59 am
2 stops18h 46m
Santiago Arturo Merino Benitez
Tue 9/15
12:22 pm-10:51 pm
2 stops38h 29m
$1,278
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Tue 9/8
7:13 am-3:56 am
2 stops16h 43m
Santiago Arturo Merino Benitez
Tue 9/15
3:27 am-10:51 pm
2 stops23h 24m
$1,278
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Wed 9/23
7:13 am-3:56 am
2 stops16h 43m
Santiago Arturo Merino Benitez
Mon 10/26
9:45 pm-6:31 pm
3 stops24h 46m
$1,281
Cheapest one-way
PortlandSantiago
PDX - SCL
PDXSCL
Portland
Tue 5/26
5:46 pm-7:23 pm
3 stops46h 37m
$403
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Portland to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santiago in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on Portland-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
PDX-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Santiago
How far ahead should I book a flight from Portland to Santiago?
Booking 23 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Portland to Santiago?
Currently, January is the cheapest month in which you can book a flight from Portland to Santiago (average of $973). Flying from Portland to Santiago in June is currently the most expensive (average of $1,335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 25, 2026.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Food
7.2
Comfort
7.9
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Portland to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Santiago by cabin class
Find flights from Portland to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Santiago flights
Browse other Portland and Santiago flight options. Last updated on April 25, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 25, 2026.
Top 4 airlines flying from Portland to Santiago
Discover the top 4 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$904 | Average$1,138 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$953 | Average$995 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$954 | Average$1,228 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$973 | Average$1,173 | FlexibilityNo cancel fee | On-time71% |