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$386+ Cheap flights from Portland (PDX) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Find cheap flights from Portland to Santiago with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Portland to Santiago Arturo Merino Benitez are usually found in January or July, booked 25 days in advance, depart on a Monday or Tuesday and return on a Wednesday

Cheap flight deals from Portland to Santiago

Cheapest flights from Portland to Santiago
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/168:35 amPDX - SCL
2 stops18h 10mAmerican Airlines
Tue 1/2010:35 pmSCL - PDX
2 stops21h 13mAmerican Airlines
Deal found 12/7$1,009
This Delta deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/161:45 pmPDX - SCL
2 stops22h 40mDelta
Tue 1/2011:10 pmSCL - PDX
2 stops23h 25mDelta
Deal found 12/6$1,165
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Wed 12/2412:20 pmSCL - PDX
2 stops28h 17mMultiple Airlines
Deal found 12/7$1,280
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Wed 12/2412:20 pmSCL - PDX
2 stops28h 17mMultiple Airlines
Deal found 12/7$1,283
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Sun 12/219:30 pmSCL - PDX
2 stops31h 35mMultiple Airlines
Deal found 12/7$1,303
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/812:55 pmPDX - SCL
1 stop14h 55mUnited Airlines
Tue 12/2310:45 pmSCL - PDX
1 stop25h 58mUnited Airlines
Deal found 12/7$1,304
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Sun 12/219:30 pmSCL - PDX
2 stops31h 35mMultiple Airlines
Deal found 12/7$1,306
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Mon 12/2211:10 pmSCL - PDX
2 stops50h 50mMultiple Airlines
Deal found 12/7$1,308
This United Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:00 amPDX - SCL
3 stops21h 50mUnited Airlines
Wed 12/2410:45 pmSCL - PDX
2 stops19h 50mUnited Airlines
Deal found 12/7$1,309
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:18 amPDX - SCL
1 stop17h 17mMultiple Airlines
Mon 12/2211:10 pmSCL - PDX
2 stops29h 55mMultiple Airlines
Deal found 12/7$1,312
This American Airlines deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:30 amPDX - SCL
1 stop21h 15mAmerican Airlines
Wed 12/2410:25 pmSCL - PDX
1 stop31h 34mAmerican Airlines
Deal found 12/7$1,322

Find flight deals from Portland to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 8, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$891
(FlightHub)

One-way from

$386
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$1,228
Provider with most accurate pricing for Portland-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Santiago Arturo Merino Benitez flights.
Search Deals
From Portland to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Portland to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.

Fly from

Portland

Fly to

Santiago

Route

Depart

Return

Price

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Thu 3/19

11:55 pm-12:10 pm

1 stop16h 15m

$912

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sun 1/18

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 1/27

11:55 pm-12:00 pm

1 stop17h 05m

$937

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/16

6:30 am-7:40 am

1 stop21h 10m

Santiago Arturo Merino Benitez

Mon 3/30

11:55 pm-10:10 pm

1 stop26h 15m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 1/6

6:50 am-6:10 am

1 stop18h 20m

Santiago Arturo Merino Benitez

Tue 2/10

6:30 pm-10:47 am

2 stops21h 17m

$954

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Thu 3/5

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 3/31

8:40 pm-10:09 pm

1 stop29h 29m

$959

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 1/12

6:50 am-5:35 am

2 stops17h 45m

Santiago Arturo Merino Benitez

Tue 1/27

11:10 pm-12:46 pm

2 stops18h 36m

$959

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 3/16

6:30 am-2:10 pm

3 stops27h 40m

Santiago Arturo Merino Benitez

Mon 3/30

11:00 pm-7:03 pm

2 stops24h 03m

$959

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Tue 1/6

5:10 am-10:15 pm

3 stops36h 05m

$415

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Mon 12/29

9:50 pm-8:21 pm

2 stops41h 31m

$423

PortlandSantiago

PDX - SCL

PDXSCL

Portland

Sat 12/27

7:00 am-7:40 am

2 stops43h 40m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Showing 1-10 of 13 results
1
2

Compare providers for flights from Portland to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Portland-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Portland-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to Santiago

How far ahead should I book a flight from Portland to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Portland to Santiago. Price data was last updated on December 5, 2025.

Booking 24 days in advance of your planned departure date is, on average, the best time to get cheap flights from Portland to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Portland to Santiago?

Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PDX to SCL?

Find hourly flight availability from Portland to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 21% on flights from Portland to Santiago by exploring options for tickets in the afternoon.

How much does it cost to fly round-trip from Portland to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 8, 2025.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,010 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,078 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,044 reviews
Delta
7.9
Good
8,010 reviews

Boarding

8.1

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland to Santiago?

    Departing from Portland to Santiago will take you 18h 55m. There are 6340 mi between Portland and Santiago.

  • What are the cheapest airlines flying from Portland to Santiago round-trip?

    According to our current data, LATAM Airlines ($874), United Airlines ($953), and Delta ($954) offers the cheapest pricing from Portland to Santiago. Users have found that LATAM Airlines is 23% cheaper than the other options available to this destination.

  • Can I find deals for flights from Portland to Santiago that include hotel bookings?

    Yes. In addition to deals on Portland to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to Santiago.

  • Can I find deals for business class flights from Portland to Santiago?

    Yes. Cheapflights offers flight deals from Portland to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland to Santiago?

    Currently, August is the cheapest month in which you can book a flight from Portland to Santiago (average of $758). Flying from Portland to Santiago in May is currently the most expensive (average of $1,199). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Portland to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Boise to Santiago flights
Medford to Santiago flights
Portland to Easter Island flights
Portland to Punta Arenas flights
Portland to Temuco flights
Redmond to Santiago flights

Top 4 airlines flying from Portland to Santiago

Discover the top 4 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$882Average$1,124FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$953Average$1,022FlexibilityNo cancel feeOn-time69%
DeltaCheapest$958Average$1,197FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$973Average$1,173FlexibilityNo cancel feeOn-time71%

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