$454+ Cheap flights from Portland (PDX) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/1. Fares are subject to change and may not be available on all flights or dates of travel.
PDX — SCL
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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Find cheap flights from Portland to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to Santiago
Cheapest
Best
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Cheapest flights from Portland to SantiagoExplore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Portland to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Air Canada deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:00 am -
2 stops21h 15m
Fri 12/118:25 am -
2 stops39h 06m
Deal found 9/8![Air Canada logo]()
$928
This Air Canada deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:00 am -
2 stops39h 50m
Fri 12/258:25 am -
2 stops39h 06m
Deal found 9/5![Air Canada logo]()
$962
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:10 am -
1 stop18h 45m
Wed 12/911:55 pm -
1 stop17h 08m
Deal found 9/5![LATAM Airlines logo]()
$980
This CheapOair deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:00 am -
2 stops45h 15m
Tue 1/268:25 am -
2 stops41h 21m
Deal found 9/9![Air Canada logo]()
$997
This Mytrip deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:15 pm -
3 stops34h 23m
Thu 12/109:55 pm -
3 stops25h 36m
Deal found 9/5![Multiple Airlines logo]()
$1,006
This FlightHub deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:10 am -
1 stop18h 45m
Sun 12/68:25 pm -
2 stops20h 38m
Deal found 9/6![LATAM Airlines logo]()
$1,027
This FlightHub deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:08 am -
2 stops20h 37m
Mon 10/2611:55 pm -
1 stop16h 16m
Deal found 9/7![LATAM Airlines logo]()
$1,028
This Justfly.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am -
1 stop20h 25m
Fri 10/3011:55 pm -
1 stop16h 28m
Deal found 9/6![LATAM Airlines logo]()
$1,034
Best flights from Portland to SantiagoDiscover carefully curated flight deals from Portland to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Portland to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Air Canada deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:00 am -
2 stops21h 15m
Fri 12/118:25 am -
2 stops39h 06m
Deal found 9/8![Air Canada logo]()
$928
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/110:00 am -
1 stop14h 35m
Wed 3/1011:55 pm -
1 stop17h 23m
Deal found 9/9![LATAM Airlines logo]()
$1,035
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:04 am -
1 stop20h 36m
Tue 1/1911:00 pm -
1 stop16h 56m
Deal found 9/5![Delta logo]()
$1,095
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1312:51 pm -
1 stop14h 59m
Wed 2/310:45 pm -
1 stop18h 34m
Deal found 9/8![United Airlines logo]()
$1,095
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:08 am -
2 stops19h 32m
Mon 11/211:55 pm -
1 stop17h 16m
Deal found 9/4![LATAM Airlines logo]()
$1,056
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:05 pm -
2 stops19h 35m
Mon 1/187:30 am -
2 stops21h 21m
Deal found 9/7![Delta logo]()
$1,097
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/198:45 am -
2 stops19h 05m
Tue 2/910:45 pm -
3 stops24h 35m
Deal found 9/4![United Airlines logo]()
$1,100
This Justfly.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/811:59 am -
1 stop14h 41m
Thu 12/2411:55 pm -
1 stop18h 29m
Deal found 9/8![LATAM Airlines logo]()
$1,071
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/121:45 pm -
2 stops23h 15m
Mon 1/187:30 am -
2 stops21h 21m
Deal found 9/7![Delta logo]()
$1,097
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:57 am -
2 stops16h 43m
Thu 12/249:50 pm -
2 stops27h 26m
Deal found 9/8![Delta logo]()
$1,100
Last-minute flights from Portland to SantiagoDiscover last-minute flight deals from Portland to Santiago. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to Santiago. Data last updated September 9, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/236:08 am -
2 stops20h 37m
Mon 10/2611:55 pm -
1 stop16h 16m
Deal found 9/7![LATAM Airlines logo]()
$1,028
This Justfly.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:08 am -
2 stops19h 32m
Mon 11/27:30 am -
2 stops19h 49m
Deal found 9/4![LATAM Airlines logo]()
$1,080
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:10 am -
1 stop20h 15m
Sun 10/1111:55 pm -
1 stop24h 55m
Deal found 9/5![LATAM Airlines logo]()
$1,057
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:08 am -
2 stops19h 27m
Thu 10/2910:50 pm -
1 stop25h 44m
Deal found 9/5![Multiple Airlines logo]()
$1,056
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/193:30 pm -
3 stops35h 55m
Mon 11/29:55 pm -
3 stops25h 36m
Deal found 9/8![Multiple Airlines logo]()
$1,066
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:00 pm -
2 stops26h 35m
Mon 11/211:10 pm -
2 stops18h 28m
Deal found 9/8![Delta logo]()
$1,090
This LATAM Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:00 am -
1 stop20h 25m
Tue 10/2711:10 pm -
1 stop23h 59m
Deal found 9/5![LATAM Airlines logo]()
$1,072
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:30 am -
2 stops20h 40m
Tue 10/2710:15 pm -
2 stops22h 48m
Deal found 9/5![American Airlines logo]()
$1,089
This Justfly.com deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:00 am -
1 stop20h 25m
Fri 10/3011:55 pm -
1 stop16h 28m
Deal found 9/6![LATAM Airlines logo]()
$1,034
One-way flights from Portland to SantiagoSearch for one-way flight options from Portland to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Portland to Santiago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Mytrip deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:10 pm -
3 stops30h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![Multiple Airlines logo]()
$454
This Air Canada deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/410:00 am -
2 stops21h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Air Canada logo]()
$507
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:33 pm -
3 stops28h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$555
This LATAM Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:20 am -
1 stop18h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![LATAM Airlines logo]()
$648
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:00 am -
1 stop18h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![LATAM Airlines logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/64:05 pm -
3 stops59h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![United Airlines logo]()
$763
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:00 am -
2 stops37h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Multiple Airlines logo]()
$1,756
This LATAM Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/66:04 am -
3 stops24h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/4![LATAM Airlines logo]()
$2,768
Find flight deals from Portland to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PDX) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $928 (Air Canada) |
One-way from | $454 (Mytrip) |
Popular in | July |
Cheapest in | February |
Average price | $1,097 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Portland to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Mon 1/4
7:33 pm-5:25 am
3 stops28h 52m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$555
Quickest round-trip
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Tue 12/1
6:20 am-5:35 am
1 stop18h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$648
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Sat 2/6
7:00 am-6:55 am
1 stop18h 55m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-7:00 pm
Nonstop0h 00m
$731
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Mon 12/7
10:00 am-12:15 pm
2 stops21h 15m
Santiago Arturo Merino Benitez
Fri 12/11
8:25 am-6:31 pm
2 stops39h 06m
$928
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Mon 3/1
10:00 am-5:35 am
1 stop14h 35m
Santiago Arturo Merino Benitez
Wed 3/10
11:55 pm-12:18 pm
1 stop17h 23m
$1,035
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Fri 10/2
6:08 am-5:40 am
2 stops19h 32m
Santiago Arturo Merino Benitez
Mon 11/2
11:55 pm-12:11 pm
1 stop17h 16m
$1,056
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Tue 12/8
11:59 am-7:40 am
1 stop14h 41m
Santiago Arturo Merino Benitez
Thu 12/24
11:55 pm-1:24 pm
1 stop18h 29m
$1,071
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Tue 1/12
6:04 am-7:40 am
1 stop20h 36m
Santiago Arturo Merino Benitez
Tue 1/19
11:00 pm-10:56 am
1 stop16h 56m
$1,095
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Wed 1/13
12:51 pm-8:50 am
1 stop14h 59m
Santiago Arturo Merino Benitez
Wed 2/3
10:45 pm-12:19 pm
1 stop18h 34m
$1,095
PortlandSantiago
PDX Portland - SCL Santiago Arturo Merino Benitez
PDXSCL
Portland
Mon 1/11
5:05 pm-5:40 pm
2 stops19h 35m
Santiago Arturo Merino Benitez
Mon 1/18
7:30 am-11:51 pm
2 stops21h 21m
$1,097
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Portland to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Portland-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Portland-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Portland with our price prediction graph.
PDX-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 9, 2026.
Read through reviews of airlines operating flights from Portland to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Entertainment
7.8
Food
7.2
Overall
7.8
Crew
8.5
Boarding
8.1
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentJorge,Aug 2026
TPA - ATL
Related info for your journey
Find useful and relevant information for your journey from Portland to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Portland to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Portland to Santiago by cabin class
Find flights from Portland to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and Santiago flights
Browse other Portland and Santiago flight options. Last updated on September 9, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
Top 4 airlines flying from Portland to Santiago
Discover the top 4 airlines that operate flights from Portland to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$818 | Average$1,237 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$912 | Average$1,113 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$951 | Average$1,154 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$953 | Average$1,034 | FlexibilityNo cancel fee | On-time69% |