Premium Business offers lie-flat beds with open suites on select aircraft.
LATAM+ offers more legroom and earlier boarding in economy class.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $453 (Mytrip) |
One-way from | $210 (Kiwi.com) |
Popular in | December |
Cheapest in | May |
Average price | $938 |
Good round-trip deal | $666 or less |
Good one-way deal | $393 or less |
Fly from
Fly to
Route
Depart
Return
Price
MiamiSantiago
MIA - SCL
MIASCL
Miami
Tue 1/20
8:45 pm-7:00 am
Nonstop8h 15m
Santiago Arturo Merino Benitez
Tue 1/27
12:35 pm-7:20 am
1 stop20h 45m
MiamiSantiago
MIA - SCL
MIASCL
Miami
Fri 3/13
6:10 pm-12:15 pm
2 stops17h 05m
Santiago Arturo Merino Benitez
Thu 3/19
1:35 am-4:50 pm
2 stops16h 15m
MiamiSantiago
MIA - SCL
MIASCL
Miami
Thu 1/8
8:40 am-6:40 am
1 stop20h 00m
Santiago Arturo Merino Benitez
Thu 1/22
9:05 pm-7:20 am
1 stop12h 15m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sun 2/8
12:42 am-6:00 am
1 stop24h 18m
Santiago Arturo Merino Benitez
Thu 2/19
12:28 pm-11:20 pm
1 stop15h 52m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Tue 2/3
12:42 am-8:20 pm
1 stop14h 38m
Santiago Arturo Merino Benitez
Thu 2/19
12:28 pm-11:20 pm
1 stop15h 52m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sun 1/11
12:42 am-8:20 pm
1 stop14h 38m
Santiago Arturo Merino Benitez
Mon 2/2
12:28 pm-11:20 pm
1 stop15h 52m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Mon 2/9
12:42 am-8:20 pm
1 stop14h 38m
Santiago Arturo Merino Benitez
Wed 3/25
5:44 am-11:40 pm
1 stop21h 56m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Tue 3/3
4:45 pm-7:40 am
1 stop12h 55m
Santiago Arturo Merino Benitez
Tue 3/17
4:35 am-12:46 am
2 stops21h 11m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Wed 3/25
10:44 am-7:40 am
1 stop19h 56m
Santiago Arturo Merino Benitez
Thu 4/2
8:05 am-12:46 am
2 stops17h 41m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Thu 3/12
12:40 pm-7:50 am
1 stop18h 10m
Santiago Arturo Merino Benitez
Thu 3/19
9:45 pm-11:30 am
1 stop14h 45m
Currently, June is the cheapest month in which you can book a flight from USA to Santiago (average of $143). Flying from USA to Santiago in February is currently the most expensive (average of $505). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from USA to Santiago in the evening. Doing so could potentially save you 6% on the flight price compared to flying in the afternoon, which is usually more expensive.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Saturday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from US0 to SCL are scheduled on a Monday (4 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (3 on average).
About 23% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 191 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Friday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Star Peru have had the lowest number of delays on this route, with just 5% of flights being delayed.
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Boarding
Food
Crew
Entertainment
Overall
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$229 | Average$678 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$786 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$396 | Average$814 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$866 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$823 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$504 | Average$875 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$650 | Average$729 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$694 | Average$761 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$758 | Average$1,037 | FlexibilityNo cancel fee | On-timeN/A |