Premium Business offers lie-flat beds with open suites on select aircraft.
LATAM+ offers more legroom and earlier boarding in economy class.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $453 (Cheapflightsfares) |
One-way from | $203 (Arajet) |
Popular in | December |
Cheapest in | May |
Average price | $999 |
Good round-trip deal | $639 or less |
Good one-way deal | $383 or less |
Fly from
Fly to
Route
Depart
Return
Price
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Mon 1/12
5:00 am-8:50 am
1 stop22h 50m
Santiago Arturo Merino Benitez
Tue 2/3
10:45 pm-7:00 pm
1 stop25h 15m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Wed 1/14
1:19 pm-8:50 am
1 stop14h 31m
Santiago Arturo Merino Benitez
Sun 2/1
10:45 pm-5:50 pm
1 stop24h 05m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Tue 1/13
5:00 am-8:50 am
1 stop22h 50m
Santiago Arturo Merino Benitez
Sun 2/1
10:45 pm-5:50 pm
1 stop24h 05m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sat 2/7
11:59 pm-8:50 am
1 stop27h 51m
Santiago Arturo Merino Benitez
Wed 2/18
10:45 pm-2:57 pm
1 stop21h 12m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sun 1/18
4:10 pm-8:50 am
1 stop35h 40m
Santiago Arturo Merino Benitez
Sun 2/1
10:45 pm-5:50 pm
1 stop24h 05m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sun 1/4
7:02 am-8:50 am
1 stop20h 48m
Santiago Arturo Merino Benitez
Wed 2/18
10:45 pm-5:54 pm
1 stop24h 09m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sun 1/18
6:00 am-8:15 am
1 stop24h 15m
Santiago Arturo Merino Benitez
Sun 1/25
10:35 pm-11:12 pm
2 stops26h 37m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Wed 12/10
12:30 pm-7:00 am
2 stops16h 30m
Santiago Arturo Merino Benitez
Wed 12/17
9:30 pm-9:11 am
1 stop13h 41m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sun 12/7
12:30 pm-5:35 am
2 stops15h 05m
Santiago Arturo Merino Benitez
Wed 12/10
11:25 pm-6:21 pm
2 stops20h 56m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sun 2/15
10:57 am-5:35 am
2 stops16h 38m
Santiago Arturo Merino Benitez
Wed 2/25
11:30 pm-11:41 am
1 stop14h 11m
Currently, June is the cheapest month in which you can book a flight from USA to Santiago (average of $143). Flying from USA to Santiago in February is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from USA to Santiago in the evening. Doing so could potentially save you 7% on the flight price compared to flying at noon, which is usually more expensive.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Saturday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from US0 to SCL are scheduled on a Monday (4 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (3 on average).
About 23% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 191 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Friday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Star Peru have had the lowest number of delays on this route, with just 5% of flights being delayed.
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
Crew
Food
Boarding
Overall
Entertainment
Comfort
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$231 | Average$678 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$771 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$396 | Average$812 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$853 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$834 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$513 | Average$859 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$650 | Average$729 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$694 | Average$767 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$758 | Average$1,139 | FlexibilityNo cancel fee | On-timeN/A |