$232+ Cheap flights from the United States to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — SCL
Dec 14 — Dec 211
Round-trip
1 adult, Economy
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Cheapest flights from USA to SantiagoExplore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
Explore the most affordable flight options available from USA to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:00 pm -
1 stop28h 36m
Thu 11/2612:15 pm -
1 stop11h 46m
Deal found 11/12![Copa Airlines logo]()
$485
This Avianca deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm -
1 stop21h 10m
Fri 2/197:30 am -
1 stop15h 05m
Deal found 11/9![Avianca logo]()
$487
This Trip.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:10 pm -
1 stop29h 35m
Sat 11/212:10 am -
1 stop14h 15m
Deal found 11/13![Avianca logo]()
$490
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:25 pm -
1 stop11h 00m
Mon 12/1410:30 pm -
1 stop18h 46m
Deal found 11/12![American Airlines logo]()
$494
This Trip.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:10 pm -
1 stop24h 55m
Wed 11/184:15 pm -
1 stop30h 20m
Deal found 11/12![Avianca logo]()
$495
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:55 am -
1 stop20h 50m
Tue 11/1710:30 pm -
1 stop14h 30m
Deal found 11/12![American Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop23h 45m
Tue 11/2410:30 pm -
1 stop19h 04m
Deal found 11/13![American Airlines logo]()
$500
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:57 pm -
2 stops17h 18m
Thu 12/1011:15 pm -
1 stop24h 32m
Deal found 11/13![American Airlines logo]()
$507
This Justfly.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm -
1 stop21h 10m
Sun 2/214:15 pm -
1 stop30h 20m
Deal found 11/9![Avianca logo]()
$510
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:43 am -
1 stop21h 07m
Thu 12/1010:45 pm -
1 stop15h 41m
Deal found 11/12![United Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:28 pm -
1 stop15h 22m
Tue 12/1510:45 pm -
2 stops25h 14m
Deal found 11/9![United Airlines logo]()
$550
This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:20 pm -
1 stop13h 20m
Tue 12/111:10 pm -
1 stop13h 51m
Deal found 11/11![LATAM Airlines logo]()
$566
Best flights from USA to SantiagoDiscover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
Discover carefully curated flight deals from USA to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/143:10 pm -
1 stop14h 30m
Wed 2/108:25 pm -
2 stops16h 47m
Deal found 11/11![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
3 stops24h 50m
Mon 12/1410:45 pm -
1 stop20h 00m
Deal found 11/13![United Airlines logo]()
$550
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2112:45 pm -
1 stop13h 05m
Thu 2/251:41 am -
1 stop13h 01m
Deal found 11/10![Copa Airlines logo]()
$659
This Arajet deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/71:15 pm -
1 stop12h 20m
Sat 1/169:25 am -
1 stop12h 17m
Deal found 11/13![Arajet logo]()
$717
This Justfly.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/411:00 am -
1 stop17h 50m
Thu 4/810:55 pm -
1 stop19h 10m
Deal found 11/11![LATAM Airlines logo]()
$732
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/199:55 am -
1 stop19h 30m
Wed 4/2810:55 pm -
1 stop23h 31m
Deal found 11/10![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:15 am -
2 stops23h 35m
Wed 12/910:45 pm -
2 stops17h 47m
Deal found 11/12![United Airlines logo]()
$550
This oojo deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/267:00 am -
2 stops30h 10m
Sat 2/207:30 am -
2 stops17h 40m
Deal found 11/9![Multiple Airlines logo]()
$1,122
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/111:20 pm -
1 stop16h 20m
Mon 2/811:10 pm -
1 stop16h 53m
Deal found 11/11![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/251:15 pm -
1 stop17h 35m
Sun 11/2910:45 pm -
1 stop25h 14m
Deal found 11/13![United Airlines logo]()
$555
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1612:45 pm -
1 stop15h 14m
Mon 2/221:41 am -
1 stop13h 21m
Deal found 11/12![Copa Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/131:20 pm -
1 stop16h 20m
Sun 2/77:35 am -
2 stops18h 21m
Deal found 11/11![Delta logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/178:46 am -
2 stops22h 04m
Sun 3/710:45 pm -
2 stops37h 01m
Deal found 11/12![United Airlines logo]()
$567
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/1010:45 am -
1 stop18h 10m
Sun 2/711:10 pm -
1 stop16h 53m
Deal found 11/11![Delta logo]()
$546
This Arajet deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:45 pm -
1 stop32h 50m
Fri 2/125:00 am -
1 stop12h 08m
Deal found 11/13![Arajet logo]()
$767
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:10 am -
1 stop23h 40m
Wed 12/910:45 pm -
1 stop20h 00m
Deal found 11/13![United Airlines logo]()
$596
This Delta deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/103:50 pm -
2 stops22h 15m
Tue 5/181:01 am -
2 stops22h 25m
Deal found 11/14![Delta logo]()
$546
This Arajet deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/34:45 pm -
1 stop32h 50m
Mon 2/86:00 am -
1 stop12h 23m
Deal found 11/13![Arajet logo]()
$767
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/15:45 am -
2 stops25h 05m
Tue 3/910:45 pm -
2 stops20h 30m
Deal found 11/14![United Airlines logo]()
$600
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/116:45 am -
1 stop21h 55m
Sun 1/2411:00 pm -
1 stop18h 18m
Deal found 11/9![Delta logo]()
$546
This Copa Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:15 am -
1 stop22h 23m
Wed 11/251:02 am -
1 stop26h 27m
Deal found 11/9![Copa Airlines logo]()
$806
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:05 pm -
1 stop15h 50m
Mon 12/711:50 pm -
1 stop16h 38m
Deal found 11/9![Delta logo]()
$548
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/291:15 am -
1 stop14h 00m
Tue 12/155:07 am -
1 stop22h 40m
Deal found 11/12![Copa Airlines logo]()
$806
This Arajet deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2912:55 pm -
1 stop12h 40m
Sat 1/169:25 am -
1 stop12h 17m
Deal found 11/10![Arajet logo]()
$833
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:15 am -
1 stop21h 33m
Thu 12/312:20 pm -
1 stop28h 32m
Deal found 11/10![Copa Airlines logo]()
$806
This Arajet deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arajet is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/212:45 pm -
1 stop13h 03m
Wed 1/135:00 am -
1 stop12h 15m
Deal found 11/10![Arajet logo]()
$835
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:30 am -
2 stops21h 20m
Wed 12/1610:45 pm -
2 stops20h 14m
Deal found 11/10![United Airlines logo]()
$706
This Copa Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:15 am -
1 stop19h 09m
Tue 12/112:20 pm -
1 stop28h 32m
Deal found 11/13![Copa Airlines logo]()
$806
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/612:09 pm -
1 stop16h 46m
Mon 2/84:45 am -
1 stop16h 00m
Deal found 11/13![Delta logo]()
$638
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:00 am -
2 stops21h 50m
Sun 11/2910:45 pm -
1 stop25h 14m
Deal found 11/12![United Airlines logo]()
$716
Last-minute flights from USA to SantiagoDiscover last-minute flight deals from USA to Santiago. Data last updated November 14, 2026 and is based on user searches.
Discover last-minute flight deals from USA to Santiago. Data last updated November 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:55 am -
1 stop20h 50m
Tue 11/1710:30 pm -
1 stop14h 30m
Deal found 11/12![American Airlines logo]()
$498
This Trip.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:10 pm -
1 stop24h 55m
Wed 11/184:15 pm -
1 stop30h 20m
Deal found 11/12![Avianca logo]()
$495
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:00 pm -
1 stop28h 36m
Thu 11/2612:15 pm -
1 stop11h 46m
Deal found 11/12![Copa Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop23h 45m
Tue 11/2410:30 pm -
1 stop19h 04m
Deal found 11/13![American Airlines logo]()
$500
This Trip.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:10 pm -
1 stop29h 35m
Sat 11/212:10 am -
1 stop14h 15m
Deal found 11/13![Avianca logo]()
$490
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/228:25 pm -
1 stop11h 00m
Mon 12/1410:30 pm -
1 stop18h 46m
Deal found 11/12![American Airlines logo]()
$494
This Avianca deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm -
1 stop21h 10m
Mon 2/227:30 am -
1 stop15h 05m
Deal found 11/9![Avianca logo]()
$487
This Justfly.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm -
1 stop21h 10m
Sun 2/214:15 pm -
1 stop30h 20m
Deal found 11/9![Avianca logo]()
$510
This Expedia deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:20 pm -
1 stop13h 20m
Tue 12/111:10 pm -
1 stop13h 51m
Deal found 11/11![LATAM Airlines logo]()
$566
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:43 am -
1 stop21h 07m
Thu 12/1010:45 pm -
1 stop15h 41m
Deal found 11/12![United Airlines logo]()
$546
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:28 pm -
1 stop15h 22m
Tue 12/1510:45 pm -
2 stops25h 14m
Deal found 11/9![United Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:57 pm -
2 stops17h 18m
Thu 12/1011:15 pm -
1 stop24h 32m
Deal found 11/13![American Airlines logo]()
$507
One-way flights from USA to SantiagoSearch for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
Search for one-way flight options from USA to Santiago. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
This eDestinos deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:10 am -
2 stops18h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![LATAM Airlines logo]()
$232
This LATAM Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/265:17 pm -
2 stops22h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![LATAM Airlines logo]()
$233
This FlightHub deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1311:15 am -
1 stop18h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![LATAM Airlines logo]()
$246
This FlightHub deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:25 pm -
1 stop24h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![LATAM Airlines logo]()
$248
This Copa Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/12:43 pm -
1 stop27h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Copa Airlines logo]()
$250
This eDestinos deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/195:30 am -
1 stop24h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![LATAM Airlines logo]()
$251
This LATAM Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/268:50 am -
3 stops31h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$254
This FlightHub deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/249:05 am -
1 stop25h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/14![LATAM Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:50 am -
1 stop24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Sky Airline logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/219:50 am -
1 stop24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Sky Airline logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/259:50 am -
1 stop24h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Sky Airline logo]()
$274
This Mytrip deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2410:50 am -
1 stop10h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Sky Airline logo]()
$275
Find flight deals from USA to Santiago
Keep the following information in mind while searching for USA to Santiago flight deals. Data was last updated November 14, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $479 (Avianca) |
One-way from | $232 (eDestinos) |
Popular in | December |
Cheapest in | April |
Average price | $878 |
Good round-trip deal | $902 or less |
Good one-way deal | $476 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from USA to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
Use the filters below to find and compare flights from the United States to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Wed 1/13
9:00 am-7:00 am
2 stops20h 00m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$247
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Wed 1/13
2:43 pm-8:18 pm
1 stop27h 35m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$250
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Thu 11/19
8:00 am-7:40 am
1 stop21h 40m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Mon 11/23
6:00 am-8:50 am
2 stops24h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Fri 1/8
3:10 pm-9:30 pm
3 stops28h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Tue 1/12
10:45 am-5:05 am
2 stops16h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Thu 1/14
11:15 am-6:40 am
1 stop17h 25m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$253
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Tue 1/26
8:50 am-6:00 pm
3 stops31h 10m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$254
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Sun 11/22
6:00 am-8:50 am
3 stops24h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$259
BostonSantiago
BOS Boston Logan Intl - SCL Santiago Arturo Merino Benitez
BOSSCL
Boston Logan Intl
Sat 11/21
8:00 pm-8:50 am
2 stops34h 50m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-10:00 pm
Nonstop0h 00m
$259
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from USA to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from USA with our price prediction graph.
BOS-SCL
MCO-SCL
MIA-SCL
DCA-SCL
ATL-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from the United States to Santiago
US0-SCL
BOS-SCL
MCO-SCL
MIA-SCL
DCA-SCL
What is the cheapest month to book a flight from USA to Santiago?
Currently, April is the cheapest month in which you can book a flight from USA to Santiago (average of $805). Flying from USA to Santiago in December is currently the most expensive (average of $1,149). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from US to SCL?
Find hourly flight availability from USA to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2026.
It’s typically best to fly out from USA to Santiago in the morning. Doing so could potentially save you 26% on the flight price compared to flying in the afternoon, which is usually more expensive.
How often are flights from the United States to Santiago delayed?
About 23% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 171 minutes.
What is the most punctual flight time for the United States to Santiago flights?
Historically, flights departing in the early afternoon are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on the United States to Santiago flights?
Over the last year, LATAM Airlines have had the lowest number of delays on this route, with just 15% of flights being delayed.
How far ahead should I book a flight from USA to Santiago?
The price you pay for your flight from USA to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 83 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from USA to Santiago?
Use this chart to determine the cheapest time to fly round-trip from USA to Santiago. Price data was last updated on November 7, 2026.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Tuesday evenings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for theUnited States to Santiago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your theUnited States to Santiago trip
Our travel experts
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated November 14, 2026.
Get a feel of what it's like to fly with Delta,Copa Airlines, andLATAM Airlines from the United States to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Overall
7.8
Crew
8.5
Comfort
7.8
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from USA to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Santiago flight routes
Top destinations
Alternative routes for USA to Santiago
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from USA to Santiago by cabin class
Find flights from USA to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
USA and Santiago flights
Browse other USA and Santiago flight options. Last updated on November 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 14, 2026.
USA to Santiago flights
Consider these flights traveling from USA to Santiago.
Top 10 airlines flying from USA to Santiago
Discover the top 10 airlines that operate flights from USA to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$232 | Average$533 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$290 | Average$752 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$885 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$300 | Average$552 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$343 | Average$857 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$380 | Average$940 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$406 | Average$1,340 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$483 | Average$914 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$516 | Average$918 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$798 | Average$1,193 | FlexibilityNo cancel fee | On-time74% |