Premium Business offers lie-flat beds with open suites on select aircraft.
LATAM+ offers more legroom and earlier boarding in economy class.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $457 (eDestinos) |
One-way from | $202 (Flightnetwork) |
Popular in | December |
Cheapest in | May |
Average price | $734 |
Good round-trip deal | $639 or less |
Good one-way deal | $353 or less |
Fly from
Fly to
Route
Depart
Return
Price
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Mon 12/8
12:43 am-8:50 am
1 stop27h 07m
Santiago Arturo Merino Benitez
Tue 12/16
10:45 pm-5:46 pm
1 stop24h 01m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Tue 12/9
12:43 am-8:50 am
1 stop27h 07m
Santiago Arturo Merino Benitez
Wed 12/17
10:45 pm-9:50 am
1 stop16h 05m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 12/6
5:59 pm-2:05 pm
2 stops18h 06m
Santiago Arturo Merino Benitez
Tue 12/9
4:35 am-12:12 am
2 stops21h 37m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Mon 3/16
7:00 am-7:00 am
1 stop23h 00m
Santiago Arturo Merino Benitez
Fri 3/27
11:15 pm-5:03 pm
1 stop18h 48m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sun 1/4
8:30 am-8:50 am
1 stop22h 20m
Santiago Arturo Merino Benitez
Thu 1/29
10:45 pm-11:23 am
1 stop14h 38m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Sun 1/4
2:00 pm-6:10 am
1 stop14h 10m
Santiago Arturo Merino Benitez
Sun 2/1
11:10 pm-7:40 pm
1 stop22h 30m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 12/6
8:30 am-8:50 am
1 stop22h 20m
Santiago Arturo Merino Benitez
Wed 12/10
10:45 pm-8:42 pm
1 stop23h 57m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Sat 3/14
10:25 am-7:00 am
1 stop19h 35m
Santiago Arturo Merino Benitez
Mon 3/23
11:15 pm-11:07 am
1 stop12h 52m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Fri 1/2
6:08 am-8:50 am
1 stop24h 42m
Santiago Arturo Merino Benitez
Wed 1/28
10:45 pm-11:23 am
1 stop14h 38m
BaltimoreSantiago
BWI - SCL
BWISCL
Baltimore/Washington
Sat 12/6
9:05 am-7:40 am
1 stop20h 35m
Santiago Arturo Merino Benitez
Wed 12/10
8:15 am-12:22 am
2 stops18h 07m
Currently, June is the cheapest month in which you can book a flight from USA to Santiago (average of $143). Flying from USA to Santiago in February is currently the most expensive (average of $508). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from USA to Santiago in the evening. Doing so could potentially save you 7% on the flight price compared to flying in the afternoon, which is usually more expensive.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Saturday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from US0 to SCL are scheduled on a Wednesday (8 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).
About 23% of weekly flights between $[0, place:'genitive'] and $[1, place:'genitive'] have experienced delays in the past year, with the average delay time being 191 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Over the last year, La Costena have had the lowest number of delays on this route, with no flights being classified as delayed.
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
Boarding
Crew
Comfort
Entertainment
Overall
Food
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$680 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$779 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$437 | Average$885 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$463 | Average$824 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$862 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$855 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$650 | Average$729 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$694 | Average$767 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$758 | Average$1,154 | FlexibilityNo cancel fee | On-timeN/A |