Premium Business offers lie-flat beds with open suites on select aircraft.
LATAM+ offers more legroom and earlier boarding in economy class.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $438 (Booking.com) |
One-way from | $199 (eDestinos) |
Popular in | December |
Cheapest in | May |
Average price | $734 |
Good round-trip deal | $639 or less |
Good one-way deal | $353 or less |
Fly from
Fly to
Route
Depart
Return
Price
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 11/29
1:13 am-12:06 am
1 stop20h 53m
Santiago Arturo Merino Benitez
Sun 12/7
12:20 pm-3:22 am
1 stop17h 02m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Wed 12/3
3:32 pm-6:01 am
1 stop12h 29m
Santiago Arturo Merino Benitez
Fri 12/5
12:20 pm-3:22 am
1 stop17h 02m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Mon 1/5
1:12 am-12:32 am
1 stop21h 20m
Santiago Arturo Merino Benitez
Wed 1/28
5:44 am-3:13 am
1 stop23h 29m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Tue 1/6
3:00 pm-7:40 am
1 stop14h 40m
Santiago Arturo Merino Benitez
Wed 1/28
6:30 pm-11:44 am
2 stops19h 14m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 12/6
12:30 pm-7:40 am
1 stop17h 10m
Santiago Arturo Merino Benitez
Fri 2/6
11:10 pm-5:02 pm
1 stop19h 52m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Thu 3/12
1:00 pm-7:00 am
1 stop17h 00m
Santiago Arturo Merino Benitez
Mon 3/23
11:15 pm-2:51 pm
1 stop16h 36m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Thu 3/12
1:00 pm-5:35 am
2 stops15h 35m
Santiago Arturo Merino Benitez
Fri 3/20
11:15 pm-12:00 pm
1 stop13h 45m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Wed 3/18
8:42 pm-12:34 am
1 stop23h 52m
Santiago Arturo Merino Benitez
Tue 3/31
1:30 am-6:25 pm
1 stop20h 55m
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 4/13
10:38 pm-11:32 pm
1 stop22h 54m
Santiago Arturo Merino Benitez
Wed 4/22
4:20 am-6:16 pm
1 stop15h 56m
San FranciscoSantiago
SFO - SCL
SFOSCL
San Francisco
Sun 2/1
7:18 am-8:50 am
1 stop20h 32m
Santiago Arturo Merino Benitez
Tue 2/17
10:45 pm-12:11 pm
1 stop18h 26m
Currently, June is the cheapest month in which you can book a flight from USA to Santiago (average of $143). Flying from USA to Santiago in February is currently the most expensive (average of $503). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from USA to Santiago in the evening. Doing so could potentially save you 7% on the flight price compared to flying in the afternoon, which is usually more expensive.
Travelers seeking maximum savings on their USA to Santiago flight should consider departing on Saturday evenings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The most flights from US0 to SCL are scheduled on a Friday (5 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (4 on average).
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
Overall
Comfort
Boarding
Crew
Entertainment
Food
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$680 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$779 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$437 | Average$885 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$463 | Average$824 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$862 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$855 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$650 | Average$729 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$694 | Average$767 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$758 | Average$1,154 | FlexibilityNo cancel fee | On-timeN/A |