Premium Business offers lie-flat beds with open suites on select aircraft.
LATAM+ offers more legroom and earlier boarding in economy class.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $480 (FlightHub) |
One-way from | $221 (Kiwi.com) |
Popular in | December |
Cheapest in | May |
Average price | $938 |
Good round-trip deal | $664 or less |
Good one-way deal | $264 or less |
Fly from
Fly to
Route
Depart
Return
Price
MiamiSantiago
MIA - SCL
MIASCL
Miami
Fri 1/9
8:40 am-10:15 pm
1 stop11h 35m
Santiago Arturo Merino Benitez
Fri 1/30
1:35 am-3:50 pm
1 stop16h 15m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Thu 3/12
12:47 pm-7:40 am
1 stop17h 53m
Santiago Arturo Merino Benitez
Sun 3/22
10:10 pm-2:39 pm
1 stop17h 29m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 3/14
5:25 pm-7:40 am
1 stop13h 15m
Santiago Arturo Merino Benitez
Fri 3/20
10:10 pm-9:58 am
1 stop12h 48m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Thu 3/12
12:47 pm-7:40 am
1 stop17h 53m
Santiago Arturo Merino Benitez
Fri 3/20
10:10 pm-11:55 am
1 stop14h 45m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Wed 3/11
3:35 pm-7:40 am
1 stop15h 05m
Santiago Arturo Merino Benitez
Wed 3/25
6:40 am-12:31 am
2 stops18h 51m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Tue 3/10
1:19 pm-5:55 am
1 stop15h 36m
Santiago Arturo Merino Benitez
Wed 3/25
10:10 pm-11:52 am
1 stop14h 42m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sat 3/14
10:53 am-7:40 am
1 stop19h 47m
Santiago Arturo Merino Benitez
Tue 3/24
10:10 pm-11:52 am
1 stop14h 42m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Sun 3/15
3:35 pm-7:40 am
1 stop15h 05m
Santiago Arturo Merino Benitez
Mon 3/23
10:10 pm-11:52 am
1 stop14h 42m
Washington, D.C.Santiago
IAD - SCL
IADSCL
Washington, D.C. Dulles Intl
Fri 1/23
12:40 pm-6:10 am
1 stop15h 30m
Santiago Arturo Merino Benitez
Sun 2/1
11:10 pm-2:45 pm
1 stop17h 35m
BostonSantiago
BOS - SCL
BOSSCL
Boston Logan Intl
Mon 3/23
7:05 am-6:25 am
2 stops22h 20m
Santiago Arturo Merino Benitez
Thu 3/26
5:10 pm-7:35 am
1 stop15h 25m
Currently, June is the cheapest month in which you can book a flight from USA to Santiago (average of $143). Flying from USA to Santiago in February is currently the most expensive (average of $506). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from USA to Santiago in the morning. Doing so could potentially save you 21% on the flight price compared to flying in the afternoon, which is usually more expensive.
The most flights from US0 to SCL are scheduled on a Monday (4 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (3 on average).
About 23% of weekly flights between United States and Santiago have experienced delays in the past year, with the average delay time being 191 minutes.
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the morning tend to experience delays more often.
Friday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Over the last year, Star Peru have had the lowest number of delays on this route, with just 5% of flights being delayed.
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
Comfort
Crew
Boarding
Entertainment
Food
Overall
Reviews
Jim,Nov 2025
AVL - ATL
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$190 | Average$448 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$220 | Average$659 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$254 | Average$754 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$396 | Average$798 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$463 | Average$850 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$501 | Average$828 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$513 | Average$859 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$650 | Average$729 | FlexibilityNo cancel fee | On-time73% | |
| Cheapest$697 | Average$792 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$758 | Average$1,148 | FlexibilityNo cancel fee | On-timeN/A |