$183+ Cheap flights from Medford to San Luis Obispo (MFR - SBP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — SBP
May 29 — Jun 51
Round-trip
1 adult, Economy
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Find cheap flights from Medford to San Luis Obispo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to San Luis Obispo
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Cheapest flights from Medford to San Luis ObispoExplore the most affordable flight options available from Medford to San Luis Obispo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Medford to San Luis Obispo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 pm
MFR
- SBP
1 stop3h 37m
United Airlines
Mon 5/256:25 am
SBP
- MFR
1 stop5h 39m
United Airlines
Deal found 4/27![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am
MFR
- SBP
1 stop5h 41m
United Airlines
Mon 9/78:00 am
SBP
- MFR
1 stop4h 02m
United Airlines
Deal found 4/24![United Airlines logo]()
$451
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:52 pm
MFR
- SBP
1 stop7h 53m
Alaska Airlines
Thu 7/167:34 pm
SBP
- MFR
1 stop4h 30m
Alaska Airlines
Deal found 4/28![Alaska Airlines logo]()
$474
This Alaska Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:00 am
MFR
- SBP
1 stop16h 50m
Alaska Airlines
Mon 9/73:24 pm
SBP
- MFR
2 stops21h 33m
Alaska Airlines
Deal found 4/24![Alaska Airlines logo]()
$540
This Alaska Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:41 pm
MFR
- SBP
1 stop25h 06m
Alaska Airlines
Mon 5/257:35 am
SBP
- MFR
2 stops33h 29m
Alaska Airlines
Deal found 4/27![Alaska Airlines logo]()
$561
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:08 pm
MFR
- SBP
1 stop8h 02m
American Airlines
Sun 5/36:06 am
SBP
- MFR
1 stop7h 19m
American Airlines
Deal found 4/27![American Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:07 pm
MFR
- SBP
2 stops9h 37m
United Airlines
Sun 5/32:15 pm
SBP
- MFR
1 stop3h 40m
United Airlines
Deal found 4/27![United Airlines logo]()
$586
Best flights from Medford to San Luis ObispoDiscover carefully curated flight deals from Medford to San Luis Obispo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Medford to San Luis Obispo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 pm
MFR
- SBP
1 stop3h 37m
United Airlines
Mon 5/256:25 am
SBP
- MFR
1 stop5h 39m
United Airlines
Deal found 4/27![United Airlines logo]()
$408
This Expedia deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:52 pm
MFR
- SBP
1 stop7h 53m
Alaska Airlines
Thu 7/167:34 pm
SBP
- MFR
1 stop4h 30m
Alaska Airlines
Deal found 4/28![Alaska Airlines logo]()
$474
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am
MFR
- SBP
1 stop5h 41m
United Airlines
Mon 9/78:00 am
SBP
- MFR
1 stop4h 02m
United Airlines
Deal found 4/24![United Airlines logo]()
$451
This Alaska Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:00 am
MFR
- SBP
1 stop16h 50m
Alaska Airlines
Mon 9/73:24 pm
SBP
- MFR
2 stops21h 33m
Alaska Airlines
Deal found 4/24![Alaska Airlines logo]()
$540
This Alaska Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:41 pm
MFR
- SBP
1 stop25h 06m
Alaska Airlines
Mon 5/257:35 am
SBP
- MFR
2 stops33h 29m
Alaska Airlines
Deal found 4/27![Alaska Airlines logo]()
$561
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:52 pm
MFR
- SBP
2 stops10h 52m
United Airlines
Thu 5/147:16 am
SBP
- MFR
2 stops10h 39m
United Airlines
Deal found 4/25![United Airlines logo]()
$729
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 am
MFR
- SBP
2 stops13h 28m
Alaska Airlines
Mon 5/257:35 am
SBP
- MFR
2 stops16h 24m
Alaska Airlines
Deal found 4/27![Alaska Airlines logo]()
$873
Last-minute flights from Medford to San Luis ObispoDiscover last-minute flight deals from Medford to San Luis Obispo. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to San Luis Obispo. Data last updated April 29, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:08 pm
MFR
- SBP
1 stop8h 02m
American Airlines
Sun 5/36:06 am
SBP
- MFR
1 stop7h 19m
American Airlines
Deal found 4/27![American Airlines logo]()
$581
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:07 pm
MFR
- SBP
2 stops9h 37m
United Airlines
Sun 5/32:15 pm
SBP
- MFR
1 stop3h 40m
United Airlines
Deal found 4/27![United Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:52 pm
MFR
- SBP
2 stops10h 52m
United Airlines
Thu 5/147:16 am
SBP
- MFR
2 stops10h 39m
United Airlines
Deal found 4/25![United Airlines logo]()
$729
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 pm
MFR
- SBP
1 stop3h 37m
United Airlines
Mon 5/256:25 am
SBP
- MFR
1 stop5h 39m
United Airlines
Deal found 4/27![United Airlines logo]()
$408
This Expedia deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:35 am
MFR
- SBP
2 stops13h 28m
Alaska Airlines
Mon 5/257:35 am
SBP
- MFR
2 stops16h 24m
Alaska Airlines
Deal found 4/27![Alaska Airlines logo]()
$873
This Alaska Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:41 pm
MFR
- SBP
1 stop25h 06m
Alaska Airlines
Mon 5/257:35 am
SBP
- MFR
2 stops33h 29m
Alaska Airlines
Deal found 4/27![Alaska Airlines logo]()
$561
One-way flights from Medford to San Luis ObispoSearch for one-way flight options from Medford to San Luis Obispo. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Medford to San Luis Obispo. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:07 pm
MFR
- SBP
1 stop5h 53m
United Airlines
Deal found 4/26![United Airlines logo]()
$183
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:00 am
MFR
- SBP
1 stop5h 38m
United Airlines
Deal found 4/25![United Airlines logo]()
$266
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:35 pm
MFR
- SBP
1 stop4h 10m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$307
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:35 pm
MFR
- SBP
1 stop4h 10m
Alaska Airlines
Deal found 4/26![Alaska Airlines logo]()
$330
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:11 pm
MFR
- SBP
2 stops9h 33m
United Airlines
Deal found 4/26![United Airlines logo]()
$489
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/149:31 pm
MFR
- SBP
3 stops46h 31m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$641
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:45 am
MFR
- SBP
3 stops14h 18m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$844
Find flight deals from Medford to San Luis Obispo
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to San Luis Obispo (SBP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $408 (United Airlines) |
One-way from | $183 (United Airlines) |
Popular in | March |
Cheapest in | December |
Average price | $516 |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to San Luis Obispo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Medford to San Luis Obispo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Thu 5/21
6:35 pm-10:12 pm
1 stop3h 37m
San Luis Obispo County
Mon 5/25
6:25 am-12:04 pm
1 stop5h 39m
$408
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Fri 9/4
6:00 am-11:41 am
1 stop5h 41m
San Luis Obispo County
Mon 9/7
8:00 am-12:02 pm
1 stop4h 02m
$451
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Sun 7/12
3:52 pm-11:45 pm
1 stop7h 53m
San Luis Obispo County
Thu 7/16
7:34 pm-12:04 am
1 stop4h 30m
$474
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Fri 9/4
7:00 am-11:50 pm
1 stop16h 50m
San Luis Obispo County
Mon 9/7
3:24 pm-12:57 pm
2 stops21h 33m
$540
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Fri 5/22
5:41 pm-6:47 pm
1 stop25h 06m
San Luis Obispo County
Mon 5/25
7:35 am-5:04 pm
2 stops33h 29m
$561
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Sun 5/10
12:52 pm-11:44 pm
2 stops10h 52m
San Luis Obispo County
Thu 5/14
7:16 am-5:55 pm
2 stops10h 39m
$729
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Thu 5/21
6:35 am-8:03 pm
2 stops13h 28m
San Luis Obispo County
Mon 5/25
7:35 am-11:59 pm
2 stops16h 24m
$873
Cheapest one-way
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Mon 5/18
2:07 pm-8:00 pm
1 stop5h 53m
$183
Quickest one-way
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Sun 6/14
6:00 am-11:38 am
1 stop5h 38m
$266
MedfordSan Luis Obispo
MFR - SBP
MFRSBP
Medford
Fri 6/12
3:52 pm-5:17 pm
2 stops25h 25m
$432
Showing 1-10 of 13 resultsSorted by cheapest first
Compare providers for flights from Medford to San Luis Obispo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to San Luis Obispo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-San Luis Obispo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-San Luis Obispo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-San Luis Obispo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-San Luis Obispo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-San Luis Obispo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to San Luis Obispo
Have a flexible travel schedule? Discover the best time to fly to San Luis Obispo from Medford with our price prediction graph.
MFR-SBP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Medford to San Luis Obispo
Reviews of airlines servicing San Luis Obispo
Get insights into the airlines that provide service to San Luis Obispo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Luis Obispo. Reviews last updated April 29, 2026.
Read through reviews of airlines operating flights from Medford to San Luis Obispo, such as Alaska Airlines and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Food
7.1
Overall
7.9
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Boarding
8.1
Crew
8.5
Food
7.1
Overall
7.9
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Boarding
8.1
Crew
8.5
Food
7.1
Overall
7.9
Entertainment
7.0
Comfort
7.8
Reviews
1 / 20
8.0
ExcellentEugene,Mar 2026
MFR - SEA
Related info for your journey
Find useful and relevant information for your journey from Medford to San Luis Obispo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Luis Obispo?
Book flights to San Luis Obispo if you plan to visit one of these locationsMorro Bay
Cambria
Arroyo Grande
San Simeon
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Complete your trip
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Medford and San Luis Obispo flights
Browse other Medford and San Luis Obispo flight options. Last updated on April 29, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Luis Obispo
Explore flights to San Luis Obispo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Top 2 airlines flying from Medford to San Luis Obispo
Discover the top 2 airlines that operate flights from Medford to San Luis Obispo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$211 | Average$424 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$242 | Average$343 | FlexibilityNo cancel fee | On-time75% |