$129+ Cheap flights from South Carolina to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SAN
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to San DiegoExplore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from South Carolina to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:25 pm -
1 stop9h 02m
Wed 10/1410:30 pm -
1 stop8h 28m
Deal found 9/9![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:05 am -
2 stops7h 45m
Tue 12/156:35 am -
1 stop10h 15m
Deal found 9/9![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:24 pm -
1 stop7h 24m
Wed 10/79:25 pm -
1 stop7h 59m
Deal found 9/8![American Airlines logo]()
$311
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:40 pm -
1 stop6h 55m
Tue 10/1310:40 pm -
1 stop11h 00m
Deal found 9/8![Southwest logo]()
$316
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Wed 10/2812:05 pm -
1 stop6h 54m
Deal found 9/10![United Airlines logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/152:04 pm -
2 stops9h 04m
Thu 12/2410:20 am -
1 stop8h 29m
Deal found 9/10![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:20 pm -
1 stop7h 50m
Tue 10/206:30 am -
2 stops10h 05m
Deal found 9/9![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:29 pm -
1 stop8h 06m
Tue 11/2412:24 pm -
1 stop6h 56m
Deal found 9/7![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:20 pm -
2 stops9h 40m
Wed 10/286:30 am -
2 stops10h 05m
Deal found 9/10![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:05 am -
1 stop9h 04m
Sat 11/712:28 pm -
1 stop6h 58m
Deal found 9/10![American Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:10 pm -
1 stop10h 05m
Thu 10/296:15 am -
2 stops10h 10m
Deal found 9/10![Southwest logo]()
$346
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Sat 10/248:45 am -
2 stops9h 56m
Deal found 9/11![United Airlines logo]()
$350
Best flights from South Carolina to San DiegoDiscover carefully curated flight deals from South Carolina to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from South Carolina to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop8h 13m
Mon 11/99:50 pm -
1 stop8h 57m
Deal found 9/10![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:25 pm -
1 stop7h 14m
Mon 10/269:45 pm -
1 stop9h 06m
Deal found 9/8![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:20 pm -
2 stops10h 45m
Wed 10/289:50 pm -
1 stop9h 10m
Deal found 9/10![Southwest logo]()
$330
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:00 am -
1 stop7h 10m
Sat 10/3111:50 am -
1 stop8h 40m
Deal found 9/9![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:25 pm -
1 stop9h 02m
Wed 10/1410:30 pm -
1 stop8h 28m
Deal found 9/9![United Airlines logo]()
$299
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:05 pm -
1 stop8h 57m
Tue 12/156:15 am -
1 stop9h 15m
Deal found 9/8![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:45 am -
1 stop7h 50m
Sat 11/76:30 pm -
2 stops12h 50m
Deal found 9/9![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Wed 10/2812:05 pm -
1 stop6h 54m
Deal found 9/10![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:20 pm -
1 stop7h 50m
Tue 10/206:30 am -
2 stops10h 05m
Deal found 9/9![Southwest logo]()
$330
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/25:20 am -
1 stop7h 36m
Tue 1/52:00 pm -
1 stop6h 55m
Deal found 9/7![Delta logo]()
$379
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:10 pm -
1 stop7h 35m
Sat 11/76:30 pm -
2 stops12h 50m
Deal found 9/10![Southwest logo]()
$346
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Sat 10/248:45 am -
2 stops9h 56m
Deal found 9/11![United Airlines logo]()
$350
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:20 pm -
1 stop7h 50m
Thu 11/1910:55 am -
2 stops7h 40m
Deal found 9/8![Southwest logo]()
$346
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:14 pm -
1 stop7h 10m
Thu 10/227:45 am -
2 stops11h 02m
Deal found 9/10![Delta logo]()
$402
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:35 pm -
1 stop7h 55m
Mon 10/2611:20 am -
2 stops8h 30m
Deal found 9/7![Southwest logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/32:30 pm -
1 stop6h 53m
Mon 12/76:15 am -
Nonstop4h 47m
Deal found 9/7![American Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:20 am -
1 stop8h 07m
Sat 10/316:26 pm -
2 stops13h 04m
Deal found 9/10![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:20 pm -
2 stops9h 40m
Sat 10/248:10 am -
2 stops9h 30m
Deal found 9/11![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 pm -
1 stop7h 29m
Fri 10/910:25 pm -
1 stop8h 36m
Deal found 9/8![Delta logo]()
$441
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:20 am -
2 stops14h 33m
Mon 11/97:41 pm -
2 stops11h 10m
Deal found 9/9![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:34 pm -
1 stop10h 03m
Wed 10/1411:58 am -
1 stop8h 59m
Deal found 9/8![American Airlines logo]()
$572
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:55 pm -
1 stop7h 15m
Sat 10/178:10 am -
2 stops9h 30m
Deal found 9/7![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:02 pm -
1 stop8h 22m
Sat 10/3110:25 pm -
1 stop8h 54m
Deal found 9/11![Delta logo]()
$453
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:27 am -
1 stop10h 42m
Mon 11/97:41 pm -
2 stops11h 40m
Deal found 9/7![United Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:00 pm -
1 stop8h 19m
Mon 1/46:15 am -
1 stop6h 00m
Deal found 9/11![Delta logo]()
$453
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:40 pm -
1 stop6h 55m
Wed 10/219:35 am -
2 stops8h 30m
Deal found 9/9![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:07 am -
1 stop9h 05m
Sat 10/3110:40 pm -
1 stop9h 33m
Deal found 9/10![United Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:00 pm -
1 stop6h 41m
Mon 1/410:40 pm -
1 stop7h 40m
Deal found 9/7![Delta logo]()
$478
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:55 pm -
1 stop6h 35m
Fri 10/167:55 am -
2 stops9h 20m
Deal found 9/8![Southwest logo]()
$421
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/222:48 pm -
1 stop10h 22m
Sat 9/2610:30 pm -
2 stops11h 05m
Deal found 9/7![United Airlines logo]()
$484
Last-minute flights from South Carolina to San DiegoDiscover last-minute flight deals from South Carolina to San Diego. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to San Diego. Data last updated September 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:50 am -
1 stop7h 35m
Sat 10/36:15 am -
1 stop8h 54m
Deal found 9/9![Delta logo]()
$357
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:24 pm -
1 stop7h 24m
Wed 10/79:25 pm -
1 stop7h 59m
Deal found 9/8![American Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/74:25 pm -
1 stop9h 02m
Wed 10/1410:30 pm -
1 stop8h 28m
Deal found 9/9![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:40 pm -
1 stop6h 55m
Tue 10/1310:40 pm -
1 stop11h 00m
Deal found 9/8![Southwest logo]()
$316
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:20 pm -
1 stop7h 50m
Tue 10/206:30 am -
2 stops10h 05m
Deal found 9/9![Southwest logo]()
$330
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:35 pm -
1 stop7h 55m
Mon 10/2611:20 am -
2 stops8h 30m
Deal found 9/7![Southwest logo]()
$355
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Wed 10/2812:05 pm -
1 stop6h 54m
Deal found 9/10![United Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:20 pm -
2 stops9h 40m
Wed 10/286:30 am -
2 stops10h 05m
Deal found 9/10![Southwest logo]()
$335
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/214:58 pm -
1 stop8h 43m
Sat 10/248:45 am -
2 stops9h 56m
Deal found 9/11![United Airlines logo]()
$350
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:55 pm -
1 stop7h 09m
Wed 10/2811:17 am -
1 stop9h 13m
Deal found 9/10![American Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:35 pm -
1 stop6h 55m
Thu 10/292:25 pm -
1 stop6h 55m
Deal found 9/10![Southwest logo]()
$341
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2912:43 pm -
1 stop6h 42m
Tue 11/106:15 am -
1 stop6h 11m
Deal found 9/10![Delta logo]()
$357
One-way flights from South Carolina to San DiegoSearch for one-way flight options from South Carolina to San Diego. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from South Carolina to San Diego. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:54 pm -
1 stop6h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$129
This Priceline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/164:47 pm -
1 stop10h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/75:07 pm -
1 stop10h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$147
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:14 pm -
1 stop7h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$150
This Frontier deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:54 pm -
1 stop6h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$160
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:40 am -
1 stop8h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Delta logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:20 am -
2 stops14h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:00 am -
2 stops14h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:47 pm -
1 stop26h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$170
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:51 pm -
1 stop10h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:10 pm -
2 stops27h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:52 am -
2 stops49h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$176
Find flight deals from South Carolina to San Diego
Keep the following information in mind while searching for South Carolina to San Diego flight deals. Data was last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (United Airlines) |
One-way from | $129 (Frontier) |
Popular in | December |
Cheapest in | February |
Average price | $521 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from South Carolina to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Thu 10/22
7:14 pm-11:24 pm
1 stop7h 10m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Wed 10/28
7:20 am-2:20 pm
1 stop10h 00m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$150
CharlestonSan Diego
CHS Charleston - SAN San Diego
CHSSAN
Charleston
Wed 10/7
6:55 pm-11:10 pm
1 stop7h 15m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
CharlotteSan Diego
CLT Charlotte Douglas - SAN San Diego
CLTSAN
Charlotte Douglas
Sat 10/17
4:10 pm-9:30 pm
1 stop8h 20m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
CharlotteSan Diego
CLT Charlotte Douglas - SAN San Diego
CLTSAN
Charlotte Douglas
Wed 10/7
7:10 pm-11:10 pm
1 stop7h 00m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
SavannahSan Diego
SAV Savannah/Hilton Head - SAN San Diego
SAVSAN
Savannah/Hilton Head
Mon 9/28
5:22 pm-11:46 pm
1 stop9h 24m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
CharlotteSan Diego
CLT Charlotte Douglas - SAN San Diego
CLTSAN
Charlotte Douglas
Tue 12/8
7:15 pm-11:05 pm
1 stop6h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
SavannahSan Diego
SAV Savannah/Hilton Head - SAN San Diego
SAVSAN
Savannah/Hilton Head
Sat 10/24
2:30 pm-7:36 pm
1 stop8h 06m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
CharlotteSan Diego
CLT Charlotte Douglas - SAN San Diego
CLTSAN
Charlotte Douglas
Sat 11/7
6:40 am-11:25 am
1 stop7h 45m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
Quickest round-trip
SavannahSan Diego
SAV Savannah/Hilton Head - SAN San Diego
SAVSAN
Savannah/Hilton Head
Sat 10/17
6:05 am-9:42 am
1 stop6h 37m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$179
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from South Carolina with our price prediction graph.
GSP-SAN
CHS-SAN
SAV-SAN
CLT-SAN
MYR-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to San Diego
USSC-SAN
GSP-SAN
CHS-SAN
SAV-SAN
CLT-SAN
What is the cheapest month to book a flight from South Carolina to San Diego?
Currently, August is the cheapest month in which you can book a flight from South Carolina to San Diego (average of $437). Flying from South Carolina to San Diego in June is currently the most expensive (average of $531). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from South Carolina to San Diego?
Airfare is below average for this route at the moment.
South Carolina to San Diego flights typically cost between $382 and $510 in October.The cheapest round-trip price found within the last 5 days was $325 on United Airlines (Oct 21-Oct 28).
How far ahead should I book a flight from South Carolina to San Diego?
Booking 85 days in advance of your planned departure date is, on average, the best time to get cheap flights from South Carolina to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
Poway
San Ysidro
La Mesa
Santee
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to San Diego
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Complete your trip
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Search flights from South Carolina to San Diego by cabin class
Find flights from South Carolina to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and San Diego flights
Browse other South Carolina and San Diego flight options. Last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 12, 2026.
South Carolina to San Diego flights
Consider these flights traveling from South Carolina to San Diego.
Top 4 airlines flying from South Carolina to San Diego
Discover the top 4 airlines that operate flights from South Carolina to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$293 | Average$466 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$296 | Average$505 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$311 | Average$531 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$324 | Average$489 | FlexibilityNo cancel fee | On-time63% |