$213+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
Jul 9 — Jul 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to San Diego
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Cheapest flights from Myrtle Beach to San DiegoExplore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:40 am
MYR
- SAN
1 stop8h 20m
Southwest
Thu 9/246:45 am
SAN
- MYR
1 stop7h 50m
Southwest
Deal found 6/8![Southwest logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:51 am
MYR
- SAN
1 stop9h 14m
American Airlines
Tue 7/76:50 am
SAN
- MYR
1 stop7h 35m
American Airlines
Deal found 6/8![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am
MYR
- SAN
1 stop8h 06m
American Airlines
Mon 11/1610:02 pm
SAN
- MYR
1 stop9h 31m
American Airlines
Deal found 6/4![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:25 am
MYR
- SAN
1 stop10h 12m
United Airlines
Mon 11/167:41 pm
SAN
- MYR
2 stops13h 59m
United Airlines
Deal found 6/4![United Airlines logo]()
$428
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:17 pm
MYR
- SAN
1 stop9h 43m
Delta
Tue 7/1412:59 pm
SAN
- MYR
1 stop7h 56m
Delta
Deal found 6/6![Delta logo]()
$435
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:15 am
MYR
- SAN
2 stops9h 00m
Southwest
Tue 7/79:40 pm
SAN
- MYR
1 stop9h 10m
Southwest
Deal found 6/8![Southwest logo]()
$436
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/289:06 am
MYR
- SAN
1 stop7h 09m
American Airlines
Wed 11/49:42 am
SAN
- MYR
2 stops9h 23m
American Airlines
Deal found 6/4![American Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1111:25 am
MYR
- SAN
2 stops13h 28m
United Airlines
Sun 11/1510:30 pm
SAN
- MYR
1 stop11h 10m
United Airlines
Deal found 6/4![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:21 pm
MYR
- SAN
1 stop7h 37m
American Airlines
Mon 11/161:44 pm
SAN
- MYR
1 stop7h 11m
American Airlines
Deal found 6/4![American Airlines logo]()
$443
Best flights from Myrtle Beach to San DiegoDiscover carefully curated flight deals from Myrtle Beach to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 9, 2026.
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:15 am
MYR
- SAN
2 stops9h 05m
Southwest
Tue 7/76:40 am
SAN
- MYR
2 stops8h 55m
Southwest
Deal found 6/5![Southwest logo]()
$446
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:02 pm
MYR
- SAN
1 stop6h 58m
Delta
Mon 8/1710:17 pm
SAN
- MYR
1 stop9h 21m
Delta
Deal found 6/8![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:08 am
MYR
- SAN
2 stops13h 26m
United Airlines
Wed 9/166:55 pm
SAN
- MYR
2 stops11h 05m
United Airlines
Deal found 6/8![United Airlines logo]()
$533
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:45 am
MYR
- SAN
2 stops11h 10m
Southwest
Mon 11/166:35 am
SAN
- MYR
1 stop8h 50m
Southwest
Deal found 6/4![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/283:20 pm
MYR
- SAN
2 stops10h 35m
Southwest
Wed 9/27:10 am
SAN
- MYR
1 stop9h 00m
Southwest
Deal found 6/6![Southwest logo]()
$472
This Delta deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
MYR
- SAN
1 stop6h 33m
Delta
Sun 7/1210:15 pm
SAN
- MYR
1 stop9h 24m
Delta
Deal found 6/5![Delta logo]()
$543
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:25 am
MYR
- SAN
2 stops9h 20m
Southwest
Tue 7/147:50 am
SAN
- MYR
2 stops10h 25m
Southwest
Deal found 6/6![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:35 am
MYR
- SAN
1 stop8h 10m
Southwest
Mon 7/138:00 am
SAN
- MYR
2 stops9h 30m
Southwest
Deal found 6/4![Southwest logo]()
$483
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/77:00 am
MYR
- SAN
2 stops9h 45m
Southwest
Mon 7/138:00 am
SAN
- MYR
2 stops9h 30m
Southwest
Deal found 6/7![Southwest logo]()
$487
Last-minute flights from Myrtle Beach to San DiegoDiscover last-minute flight deals from Myrtle Beach to San Diego. Data last updated June 9, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Diego. Data last updated June 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:51 am
MYR
- SAN
1 stop9h 14m
American Airlines
Tue 7/76:50 am
SAN
- MYR
1 stop7h 35m
American Airlines
Deal found 6/8![American Airlines logo]()
$403
This Delta deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:17 pm
MYR
- SAN
1 stop9h 43m
Delta
Tue 7/1412:59 pm
SAN
- MYR
1 stop7h 56m
Delta
Deal found 6/6![Delta logo]()
$435
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:15 am
MYR
- SAN
2 stops9h 00m
Southwest
Tue 7/79:40 pm
SAN
- MYR
1 stop9h 10m
Southwest
Deal found 6/8![Southwest logo]()
$436
This American Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:43 pm
MYR
- SAN
1 stop8h 54m
American Airlines
Fri 7/109:50 am
SAN
- MYR
2 stops8h 53m
American Airlines
Deal found 6/4![American Airlines logo]()
$443
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:16 pm
MYR
- SAN
1 stop8h 29m
American Airlines
Tue 7/149:50 am
SAN
- MYR
2 stops8h 53m
American Airlines
Deal found 6/6![American Airlines logo]()
$445
This Southwest deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/37:25 am
MYR
- SAN
2 stops9h 20m
Southwest
Tue 7/147:50 am
SAN
- MYR
2 stops10h 25m
Southwest
Deal found 6/6![Southwest logo]()
$473
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:35 am
MYR
- SAN
1 stop8h 10m
Southwest
Mon 7/138:00 am
SAN
- MYR
2 stops9h 30m
Southwest
Deal found 6/4![Southwest logo]()
$483
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/174:43 pm
MYR
- SAN
1 stop8h 54m
American Airlines
Thu 7/239:25 pm
SAN
- MYR
1 stop8h 11m
American Airlines
Deal found 6/6![American Airlines logo]()
$477
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:45 pm
MYR
- SAN
2 stops8h 35m
Southwest
Sun 8/210:40 pm
SAN
- MYR
1 stop9h 40m
Southwest
Deal found 6/5![Southwest logo]()
$472
One-way flights from Myrtle Beach to San DiegoSearch for one-way flight options from Myrtle Beach to San Diego. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
Search for one-way flight options from Myrtle Beach to San Diego. Find affordable one-way fares based on user searches. Data last updated June 9, 2026.
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:57 pm
MYR
- SAN
1 stop7h 51m
American Airlines
Deal found 6/8![American Airlines logo]()
$213
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:05 am
MYR
- SAN
2 stops11h 15m
Southwest
Deal found 6/8![Southwest logo]()
$218
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:16 pm
MYR
- SAN
1 stop8h 29m
American Airlines
Deal found 6/6![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/209:59 pm
MYR
- SAN
2 stops37h 49m
Multiple Airlines
Deal found 6/7![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:12 pm
MYR
- SAN
3 stops32h 47m
Multiple Airlines
Deal found 6/8![Multiple Airlines logo]()
$269
Find flight deals from Myrtle Beach to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $363 (Southwest) |
One-way from | $213 (American Airlines) |
Popular in | December |
Cheapest in | September |
Average price | $536 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 7/3
5:15 am-11:20 am
2 stops9h 05m
San Diego
Tue 7/7
6:40 am-6:35 pm
2 stops8h 55m
$446
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Thu 11/12
10:45 am-6:55 pm
2 stops11h 10m
San Diego
Mon 11/16
6:35 am-6:25 pm
1 stop8h 50m
$448
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Thu 8/13
7:02 pm-11:00 pm
1 stop6h 58m
San Diego
Mon 8/17
10:17 pm-10:38 am
1 stop9h 21m
$467
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 8/28
3:20 pm-10:55 pm
2 stops10h 35m
San Diego
Wed 9/2
7:10 am-7:10 pm
1 stop9h 00m
$472
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 7/3
7:25 am-1:45 pm
2 stops9h 20m
San Diego
Tue 7/14
7:50 am-9:15 pm
2 stops10h 25m
$473
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 7/3
10:35 am-3:45 pm
1 stop8h 10m
San Diego
Mon 7/13
8:00 am-8:30 pm
2 stops9h 30m
$483
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Tue 7/7
7:00 am-1:45 pm
2 stops9h 45m
San Diego
Mon 7/13
8:00 am-8:30 pm
2 stops9h 30m
$487
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Tue 9/15
10:08 am-8:34 pm
2 stops13h 26m
San Diego
Wed 9/16
6:55 pm-9:00 am
2 stops11h 05m
$533
Quickest round-trip
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Sun 7/5
6:00 am-9:33 am
1 stop6h 33m
San Diego
Sun 7/12
10:15 pm-10:39 am
1 stop9h 24m
$543
Cheapest one-way
Quickest one-way
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 10/2
4:57 pm-9:48 pm
1 stop7h 51m
$213
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Diego in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
MYR-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Diego
What is the cheapest month to book a flight from Myrtle Beach to San Diego?
Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $339). Flying from Myrtle Beach to San Diego in December is currently the most expensive (average of $627). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 9, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Boarding
8.1
Overall
7.9
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove
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Myrtle Beach and San Diego flights
Browse other Myrtle Beach and San Diego flight options. Last updated on June 9, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 9, 2026.
Top 3 airlines flying from Myrtle Beach to San Diego
Discover the top 3 airlines that operate flights from Myrtle Beach to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$495 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$350 | Average$502 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$502 | FlexibilityNo cancel fee | On-time63% |