$138+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
May 22 — May 291
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to San DiegoExplore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MYR
- SAN
1 stop6h 39m
Delta
Wed 6/31:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MYR
- SAN
1 stop9h 38m
Delta
Wed 5/271:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:15 pm
MYR
- SAN
1 stop6h 45m
American Airlines
Wed 9/239:20 pm
SAN
- MYR
1 stop9h 50m
American Airlines
Deal found 4/20![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/233:08 pm
MYR
- SAN
2 stops11h 46m
United Airlines
Wed 5/279:05 pm
SAN
- MYR
1 stop8h 59m
United Airlines
Deal found 4/20![United Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/172:30 pm
MYR
- SAN
2 stops10h 25m
Southwest
Wed 9/236:55 am
SAN
- MYR
1 stop7h 45m
Southwest
Deal found 4/20![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MYR
- SAN
1 stop6h 39m
Delta
Tue 5/191:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:30 am
MYR
- SAN
2 stops11h 44m
United Airlines
Tue 5/1910:40 pm
SAN
- MYR
1 stop9h 02m
United Airlines
Deal found 4/21![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:14 pm
MYR
- SAN
1 stop10h 25m
United Airlines
Tue 5/1910:40 pm
SAN
- MYR
1 stop9h 02m
United Airlines
Deal found 4/17![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/181:30 pm
MYR
- SAN
1 stop8h 53m
Delta
Wed 5/271:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
MYR
- SAN
2 stops12h 56m
Delta
Wed 6/31:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1811:10 am
MYR
- SAN
1 stop10h 13m
Delta
Wed 9/2310:30 pm
SAN
- MYR
1 stop8h 56m
Delta
Deal found 4/20![Delta logo]()
$362
Best flights from Myrtle Beach to San DiegoDiscover carefully curated flight deals from Myrtle Beach to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 22, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MYR
- SAN
1 stop6h 39m
Delta
Tue 5/1912:41 pm
SAN
- MYR
1 stop8h 17m
Delta
Deal found 4/21![Delta logo]()
$343
This Southwest deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/203:50 pm
MYR
- SAN
2 stops10h 05m
Southwest
Wed 6/2410:40 pm
SAN
- MYR
1 stop9h 35m
Southwest
Deal found 4/17![Southwest logo]()
$461
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:20 pm
MYR
- SAN
1 stop8h 19m
Delta
Wed 5/131:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/21![Delta logo]()
$465
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:55 am
MYR
- SAN
1 stop8h 15m
Southwest
Thu 7/910:40 pm
SAN
- MYR
1 stop9h 35m
Southwest
Deal found 4/19![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:00 am
MYR
- SAN
2 stops10h 50m
Southwest
Wed 6/2410:40 pm
SAN
- MYR
1 stop9h 35m
Southwest
Deal found 4/19![Southwest logo]()
$472
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:57 pm
MYR
- SAN
1 stop10h 41m
Delta
Tue 5/1212:41 pm
SAN
- MYR
1 stop8h 17m
Delta
Deal found 4/19![Delta logo]()
$492
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/53:57 pm
MYR
- SAN
1 stop10h 41m
Delta
Mon 5/1110:25 pm
SAN
- MYR
1 stop9h 14m
Delta
Deal found 4/17![Delta logo]()
$496
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1511:32 am
MYR
- SAN
1 stop9h 29m
Delta
Fri 5/2210:15 pm
SAN
- MYR
1 stop9h 22m
Delta
Deal found 4/17![Delta logo]()
$503
This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MYR
- SAN
1 stop6h 39m
Delta
Mon 5/181:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/18![Delta logo]()
$503
Last-minute flights from Myrtle Beach to San DiegoDiscover last-minute flight deals from Myrtle Beach to San Diego. Data last updated April 22, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Diego. Data last updated April 22, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
MYR
- SAN
1 stop6h 39m
Delta
Tue 5/1912:41 pm
SAN
- MYR
1 stop8h 17m
Delta
Deal found 4/21![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1211:30 am
MYR
- SAN
2 stops11h 44m
United Airlines
Tue 5/1910:40 pm
SAN
- MYR
1 stop9h 02m
United Airlines
Deal found 4/21![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/133:14 pm
MYR
- SAN
1 stop10h 25m
United Airlines
Tue 5/1910:40 pm
SAN
- MYR
1 stop9h 02m
United Airlines
Deal found 4/17![United Airlines logo]()
$355
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/181:30 pm
MYR
- SAN
1 stop8h 53m
Delta
Wed 5/271:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$358
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
MYR
- SAN
1 stop9h 38m
Delta
Wed 5/271:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$321
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:00 pm
MYR
- SAN
1 stop7h 46m
United Airlines
Wed 5/279:05 pm
SAN
- MYR
1 stop8h 59m
United Airlines
Deal found 4/20![United Airlines logo]()
$331
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
MYR
- SAN
2 stops12h 56m
Delta
Wed 6/31:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$361
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MYR
- SAN
1 stop6h 39m
Delta
Wed 6/31:50 pm
SAN
- MYR
1 stop7h 08m
Delta
Deal found 4/20![Delta logo]()
$299
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:54 pm
MYR
- SAN
1 stop9h 34m
Delta
Sat 6/610:25 pm
SAN
- MYR
1 stop9h 19m
Delta
Deal found 4/20![Delta logo]()
$363
One-way flights from Myrtle Beach to San DiegoSearch for one-way flight options from Myrtle Beach to San Diego. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
Search for one-way flight options from Myrtle Beach to San Diego. Find affordable one-way fares based on user searches. Data last updated April 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:14 pm
MYR
- SAN
2 stops32h 36m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:14 pm
MYR
- SAN
2 stops32h 36m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:30 am
MYR
- SAN
3 stops29h 12m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/309:50 pm
MYR
- SAN
2 stops42h 27m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/511:42 am
MYR
- SAN
2 stops36h 16m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$189
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:00 am
MYR
- SAN
1 stop9h 09m
American Airlines
Deal found 4/17![American Airlines logo]()
$199
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:04 am
MYR
- SAN
2 stops9h 09m
American Airlines
Deal found 4/19![American Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1910:24 am
MYR
- SAN
3 stops40h 26m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$206
Find flight deals from Myrtle Beach to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $299 (Delta) |
One-way from | $138 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $519 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Tue 5/12
6:00 am-9:39 am
1 stop6h 39m
San Diego
Tue 5/19
12:41 pm-11:58 pm
1 stop8h 17m
$343
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Sat 6/20
3:50 pm-10:55 pm
2 stops10h 05m
San Diego
Wed 6/24
10:40 pm-11:15 am
1 stop9h 35m
$461
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Thu 5/7
3:20 pm-8:39 pm
1 stop8h 19m
San Diego
Wed 5/13
1:50 pm-11:58 pm
1 stop7h 08m
$465
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 7/3
11:55 am-5:10 pm
1 stop8h 15m
San Diego
Thu 7/9
10:40 pm-11:15 am
1 stop9h 35m
$467
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Wed 6/17
7:00 am-2:50 pm
2 stops10h 50m
San Diego
Wed 6/24
10:40 pm-11:15 am
1 stop9h 35m
$472
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Tue 5/5
3:57 pm-11:38 pm
1 stop10h 41m
San Diego
Tue 5/12
12:41 pm-11:58 pm
1 stop8h 17m
$492
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Tue 5/5
3:57 pm-11:38 pm
1 stop10h 41m
San Diego
Mon 5/11
10:25 pm-10:39 am
1 stop9h 14m
$496
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Fri 5/15
11:32 am-6:01 pm
1 stop9h 29m
San Diego
Fri 5/22
10:15 pm-10:37 am
1 stop9h 22m
$503
Quickest round-trip
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Thu 5/14
6:00 am-9:39 am
1 stop6h 39m
San Diego
Mon 5/18
1:50 pm-11:58 pm
1 stop7h 08m
$503
Cheapest one-way
Myrtle BeachSan Diego
MYR - SAN
MYRSAN
Myrtle Beach Intl
Mon 5/11
6:14 pm-11:50 pm
2 stops32h 36m
$138
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
MYR-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Diego
What is the cheapest month to book a flight from Myrtle Beach to San Diego?
Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $365). Flying from Myrtle Beach to San Diego in December is currently the most expensive (average of $627). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 22, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Crew
8.6
Overall
8.0
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 3 airlines flying from Myrtle Beach to San Diego
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$446 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$331 | Average$502 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$437 | Average$531 | FlexibilityNo cancel fee | On-time63% |