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$359+ Cheap flights from Myrtle Beach to San Diego (MYR - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAN
מרץ 4 — מרץ 111
ד' 3/4
ד' 3/11
1 adult, Economy
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Cheap flight deals from Myrtle Beach to San Diego

Cheapest flights from Myrtle Beach to San Diego
Explore the most affordable flight options available from Myrtle Beach to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on פברואר 2, 2026.

This Delta deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ה' 2/262:21 pm
MYR
-
SAN
1 stop9h 16m
Delta
ב' 3/22:15 pm
SAN
-
MYR
1 stop6h 42m
Delta
Deal found 1/31$359
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ה' 2/2610:35 am
MYR
-
SAN
1 stop8h 40m
Southwest
א' 3/18:15 pm
SAN
-
MYR
2 stops10h 45m
Southwest
Deal found 1/31$364
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ה' 2/265:10 am
MYR
-
SAN
1 stop9h 07m
American Airlines
ב' 3/27:42 pm
SAN
-
MYR
2 stops10h 54m
American Airlines
Deal found 2/1$371
This Southwest deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ה' 4/301:45 pm
MYR
-
SAN
1 stop8h 15m
Southwest
ב' 5/49:40 pm
SAN
-
MYR
1 stop9h 55m
Southwest
Deal found 1/31$393
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ב' 2/165:18 pm
MYR
-
SAN
1 stop8h 12m
American Airlines
ו' 2/209:57 pm
SAN
-
MYR
1 stop7h 23m
American Airlines
Deal found 2/1$395
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ה' 3/53:17 pm
MYR
-
SAN
1 stop8h 50m
American Airlines
ד' 3/1112:09 pm
SAN
-
MYR
1 stop7h 19m
American Airlines
Deal found 2/2$403
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ג' 2/241:00 pm
MYR
-
SAN
2 stops12h 00m
United Airlines
ג' 3/1010:30 pm
SAN
-
MYR
1 stop10h 46m
United Airlines
Deal found 2/1$408
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ג' 2/248:15 am
MYR
-
SAN
2 stops10h 40m
Southwest
ג' 3/108:15 am
SAN
-
MYR
2 stops9h 55m
Southwest
Deal found 2/1$413

Find flight deals from Myrtle Beach to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated פברואר 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$359
(Southwest)

Popular in

December

Cheapest in

September

Average price

$437
Provider with most accurate pricing for Myrtle Beach Intl-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Diego flights.
Search Deals
From Myrtle Beach Intl to San Diego
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($81 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated פברואר 2, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Diego that are best for you.

Fly from

Myrtle Beach

Fly to

San Diego

Route

Depart

Return

Price

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

ה' 2/26

10:35 am-4:15 pm

1 stop8h 40m

San Diego

א' 3/1

9:45 pm-10:00 am

1 stop9h 15m

$359

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

ה' 2/26

5:10 am-11:17 am

1 stop9h 07m

San Diego

ב' 3/2

7:42 pm-9:36 am

2 stops10h 54m

$371

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

ב' 2/16

5:18 pm-10:30 pm

1 stop8h 12m

San Diego

ו' 2/20

9:57 pm-8:20 am

1 stop7h 23m

$395

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

ה' 4/30

1:45 pm-7:00 pm

1 stop8h 15m

San Diego

ב' 5/4

6:30 am-8:50 pm

2 stops11h 20m

$398

Myrtle BeachSan Diego

MYR - SAN

MYRSAN

Myrtle Beach Intl

ג' 2/24

1:00 pm-9:25 pm

1 stop11h 25m

San Diego

ג' 3/10

10:30 pm-12:16 pm

1 stop10h 46m

$403

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/31

Compare providers for flights from Myrtle Beach to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Diego in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Diego

What is the cheapest month to book a flight from Myrtle Beach to San Diego?

Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $165). Flying from Myrtle Beach to San Diego in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated פברואר 2, 2026.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Myrtle Beach to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,271 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,271 reviews
Southwest
8.0
Very good
4,271 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,131 reviews
Southwest
8.0
Very good
4,271 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,212 reviews
Southwest
8.0
Very good
4,271 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to San Diego?

    There are many flights that can get you from Myrtle Beach to San Diego in 8h 40m. Fly via Southwest to get the fastest option. Myrtle Beach and San Diego are separated by a distance of 2199 mi.

  • What are the cheapest airlines flying from Myrtle Beach to San Diego round-trip?

    Cheapflights users have booked flights from Myrtle Beach to San Diego round-trip from $274. Other airlines that can offer you cheap pricing are Delta, from $331, and Southwest, from $437. American Airlines is currently priced 44% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Myrtle Beach to San Diego one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $162. Delta flights start at $167 while deals on Southwest start at $206 one-way.

  • Can I find deals for flights from Myrtle Beach to San Diego that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Diego.

  • Can I find deals for business class flights from Myrtle Beach to San Diego?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Diego?

    Currently, September is the cheapest month in which you can book a flight from Myrtle Beach to San Diego (average of $165). Flying from Myrtle Beach to San Diego in August is currently the most expensive (average of $284). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Top 3 airlines flying from Myrtle Beach to San Diego

Discover the top 3 airlines that operate flights from Myrtle Beach to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated פברואר 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$274Average$452FlexibilityNo cancel feeOn-time71%
DeltaCheapest$331Average$497FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$437Average$476FlexibilityNo cancel feeOn-time63%

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