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$176+ Cheap flights from Greenville to San Francisco (GSP - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SFO
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheapflights Tip: The best prices from Greenville to San Francisco are usually found in January or August, booked 77 days in advance, depart on a Wednesday or Tuesday and return on a Saturday

Cheap flight deals from Greenville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 30, 2025.

Round-trip from

$351
(Delta)

One-way from

$176
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$482
From Greenville to San Francisco
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One-way flight from Greenville to San Francisco
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Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Greenville to San Francisco

Cheapest flights from Greenville to San Francisco
Explore the most affordable flight options available from Greenville to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1010:15 amGSP - SFO
1 stop8h 08mUnited Airlines
Tue 9/165:00 amSFO - GSP
1 stop7h 46mUnited Airlines
Deal found 6/29$351
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/301:59 pmGSP - SFO
1 stop7h 47mDelta
Tue 8/51:41 pmSFO - GSP
1 stop6h 52mDelta
Deal found 6/27$354
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/109:30 amGSP - SFO
2 stops11h 25mSouthwest
Tue 9/169:05 pmSFO - GSP
1 stop9h 45mSouthwest
Deal found 6/29$356
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:20 pmGSP - SFO
1 stop7h 17mAmerican Airlines
Sat 12/137:46 amSFO - GSP
1 stop8h 11mAmerican Airlines
Deal found 6/28$369

Cheapflights Fare Finder

Customize your flight search to find flights from Greenville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Greenville to San Francisco that are best for you.

Fly from

Greenville

Fly to

San Francisco

Route

Depart

Return

Price

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/10

10:15 am-3:23 pm

1 stop8h 08m

San Francisco

Tue 9/16

5:00 am-3:46 pm

1 stop7h 46m

$351

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 7/30

1:59 pm-6:46 pm

1 stop7h 47m

San Francisco

Mon 8/4

9:35 pm-9:01 am

1 stop8h 26m

$354

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 9/10

9:30 am-5:55 pm

2 stops11h 25m

San Francisco

Tue 9/16

9:05 pm-9:50 am

1 stop9h 45m

$356

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sat 10/11

4:20 pm-8:37 pm

1 stop7h 17m

San Francisco

Sat 12/13

7:46 am-6:57 pm

1 stop8h 11m

$369

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 9/18

2:35 pm-9:51 pm

1 stop10h 16m

$176

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 10/9

1:50 pm-11:35 pm

2 stops12h 45m

$181

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Mon 7/28

8:07 pm-12:40 am

1 stop7h 33m

$240

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Thu 9/18

9:35 am-9:46 pm

2 stops15h 11m

$288

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Fri 10/10

8:03 pm-5:21 pm

3 stops24h 18m

$390

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Sun 8/17

10:34 am-11:44 am

3 stops28h 10m

$476

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Greenville to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to San Francisco

How far ahead should I book a flight from Greenville to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Greenville to San Francisco. Price data was last updated on June 27, 2025.

The price you pay for your flight from Greenville to San Francisco may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Greenville to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $276). Flying from Greenville to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GSP to SFO?

Find hourly flight availability from Greenville to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

One of the essential ways to save on airfare from Greenville to San Francisco is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 6% on airfare.

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated June 30, 2025.
Read through reviews of airlines operating flights from Greenville to San Francisco, such as Breeze Airways, Southwest, and Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
182 reviews
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Southwest
8.0
Very good
4,278 reviews
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,973 reviews
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,852 reviews
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
182 reviews

Comfort

8.2

Boarding

8.4

Food

6.8

Crew

8.8

Entertainment

6.6

Overall

8.1

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Greenville to San Francisco round-trip?

    Currently priced at $351, Delta will fly you from Greenville to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and United Airlines - these airlines can fly you to your destination from $356 and $389, respectively. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Greenville to San Francisco one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $176. Southwest flights start at $181 while deals on Delta start at $240 one-way.

  • Can I find deals for flights from Greenville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Greenville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Francisco.

  • Can I find deals for business class flights from Greenville to San Francisco?

    Yes. Cheapflights offers flight deals from Greenville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Greenville to San Francisco (average of $276). Flying from Greenville to San Francisco in June is currently the most expensive (average of $360). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Roseville
Mountain View
South San Francisco
Livermore
Santa Cruz
Turlock
Manteca
Watsonville
Fairfield
Antioch
Hollister
Milpitas
Sunnyvale
Newark
Alameda
Hayward
Daly City
Campbell
Capitola
Foster City

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Top 4 airlines flying from Greenville to San Francisco

Discover the top 4 airlines that operate flights from Greenville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$312Average$487FlexibilityNo cancel feeOn-time69%
DeltaCheapest$326Average$467FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$346Average$483FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$366Average$488FlexibilityNo cancel feeOn-time63%

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