$140+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SFO
Sep 13 — Sep 201
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Myrtle Beach to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to San FranciscoExplore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:58 pm -
1 stop7h 59m
Mon 9/2111:30 pm -
1 stop7h 37m
Deal found 8/11![Delta logo]()
$305
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop8h 46m
Mon 9/219:15 pm -
1 stop10h 53m
Deal found 8/12![United Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop10h 35m
Tue 9/229:15 pm -
1 stop8h 44m
Deal found 8/12![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:45 pm -
1 stop9h 12m
Tue 9/156:00 am -
1 stop9h 03m
Deal found 8/12![Delta logo]()
$327
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 am -
1 stop10h 31m
Sat 9/199:53 pm -
1 stop9h 40m
Deal found 8/12![American Airlines logo]()
$336
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:40 am -
1 stop9h 20m
Fri 9/1811:05 pm -
1 stop10h 40m
Deal found 8/12![Southwest logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:15 pm -
1 stop8h 25m
Wed 9/96:12 am -
1 stop9h 33m
Deal found 8/13![American Airlines logo]()
$342
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:56 pm -
1 stop8h 01m
Mon 9/2111:30 pm -
1 stop7h 37m
Deal found 8/11![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:30 pm -
2 stops10h 00m
Mon 10/59:35 pm -
1 stop9h 10m
Deal found 8/13![Southwest logo]()
$349
Best flights from Myrtle Beach to San FranciscoDiscover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop8h 46m
Mon 9/219:15 pm -
1 stop10h 53m
Deal found 8/12![United Airlines logo]()
$306
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:30 pm -
2 stops10h 00m
Mon 10/56:15 pm -
2 stops12h 30m
Deal found 8/13![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:58 pm -
2 stops16h 31m
Tue 9/2211:30 pm -
1 stop7h 37m
Deal found 8/11![Delta logo]()
$364
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop10h 35m
Tue 9/229:15 pm -
1 stop8h 44m
Deal found 8/12![United Airlines logo]()
$321
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/112:30 pm -
2 stops10h 15m
Fri 9/187:55 pm -
2 stops11h 00m
Deal found 8/12![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:56 pm -
1 stop8h 01m
Fri 9/2511:30 pm -
1 stop7h 43m
Deal found 8/11![Delta logo]()
$415
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:15 am -
1 stop7h 50m
Sun 9/207:50 pm -
2 stops11h 25m
Deal found 8/9![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:45 am -
2 stops11h 55m
Tue 9/2211:05 pm -
2 stops11h 45m
Deal found 8/12![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/123:55 pm -
1 stop9h 30m
Mon 10/199:35 pm -
1 stop9h 10m
Deal found 8/10![Southwest logo]()
$428
Last-minute flights from Myrtle Beach to San FranciscoDiscover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated August 14, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated August 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:15 pm -
1 stop8h 25m
Wed 9/96:12 am -
1 stop9h 33m
Deal found 8/13![American Airlines logo]()
$342
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop8h 46m
Mon 9/219:15 pm -
1 stop10h 53m
Deal found 8/12![United Airlines logo]()
$306
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:24 pm -
1 stop10h 35m
Tue 9/229:15 pm -
1 stop8h 44m
Deal found 8/12![United Airlines logo]()
$321
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:45 pm -
1 stop9h 12m
Tue 9/156:00 am -
1 stop9h 03m
Deal found 8/12![Delta logo]()
$327
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:40 am -
1 stop9h 20m
Fri 9/1811:05 pm -
1 stop10h 40m
Deal found 8/12![Southwest logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 am -
1 stop10h 31m
Sat 9/199:53 pm -
1 stop9h 40m
Deal found 8/12![American Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:58 pm -
1 stop7h 59m
Mon 9/2111:30 pm -
1 stop7h 37m
Deal found 8/11![Delta logo]()
$305
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:56 pm -
1 stop8h 01m
Mon 9/2111:30 pm -
1 stop7h 37m
Deal found 8/11![Delta logo]()
$348
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:30 pm -
2 stops10h 00m
Mon 10/59:35 pm -
1 stop9h 10m
Deal found 8/13![Southwest logo]()
$349
One-way flights from Myrtle Beach to San FranciscoSearch for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
Search for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 am -
1 stop7h 40m
Deal found 8/12![Southwest logo]()
$140
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:58 pm -
1 stop7h 59m
Deal found 8/12![Delta logo]()
$153
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:45 pm -
1 stop9h 12m
Deal found 8/12![Delta logo]()
$154
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:20 pm -
2 stops9h 35m
Deal found 8/11![Southwest logo]()
$158
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:00 am -
1 stop8h 32m
Deal found 8/9![American Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:45 am -
3 stops56h 01m
Deal found 8/11![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:12 pm -
2 stops33h 02m
Deal found 8/12![Multiple Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:41 pm -
2 stops36h 33m
Deal found 8/11![Multiple Airlines logo]()
$182
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:58 pm -
3 stops43h 24m
Deal found 8/12![Multiple Airlines logo]()
$183
Find flight deals from Myrtle Beach to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (Delta) |
One-way from | $140 (Southwest) |
Popular in | April |
Cheapest in | October |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Sat 9/5
3:24 pm-9:10 pm
1 stop8h 46m
San Francisco
Mon 9/21
9:15 pm-11:08 am
1 stop10h 53m
$306
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Sat 9/5
3:24 pm-10:59 pm
1 stop10h 35m
San Francisco
Tue 9/22
9:15 pm-8:59 am
1 stop8h 44m
$321
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Mon 9/28
2:30 pm-9:30 pm
2 stops10h 00m
San Francisco
Mon 10/5
6:15 pm-9:45 am
2 stops12h 30m
$354
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Wed 9/16
6:58 pm-8:29 am
2 stops16h 31m
San Francisco
Tue 9/22
11:30 pm-10:07 am
1 stop7h 37m
$364
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Fri 9/11
2:30 pm-9:45 pm
2 stops10h 15m
San Francisco
Fri 9/18
7:55 pm-9:55 am
2 stops11h 00m
$389
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Sun 9/6
7:15 am-12:05 pm
1 stop7h 50m
San Francisco
Sun 9/20
7:50 pm-10:15 am
2 stops11h 25m
$412
Quickest round-trip
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Mon 9/21
6:56 pm-11:57 pm
1 stop8h 01m
San Francisco
Fri 9/25
11:30 pm-10:13 am
1 stop7h 43m
$415
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Sat 9/5
11:45 am-8:40 pm
2 stops11h 55m
San Francisco
Tue 9/22
11:05 pm-1:50 pm
2 stops11h 45m
$417
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Mon 10/12
3:55 pm-10:25 pm
1 stop9h 30m
San Francisco
Mon 10/19
9:35 pm-9:45 am
1 stop9h 10m
$428
Cheapest one-way
Quickest one-way
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Fri 9/11
8:10 am-12:50 pm
1 stop7h 40m
$140
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.
MYR-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Francisco
What is the cheapest month to book a flight from Myrtle Beach to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $394). Flying from Myrtle Beach to San Francisco in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to San Francisco?
Airfare is below average for this route at the moment.
Myrtle Beach to San Francisco flights typically cost between $424 and $487 in September.The cheapest round-trip price found within the last 5 days was $305 on Delta (Sep 16-Sep 21).
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated August 14, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Manteca
Turlock
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Myrtle Beach
Popular flights
San Francisco flight routes
Alternative routes for Myrtle Beach to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Myrtle Beach to San Francisco by cabin class
Find flights from Myrtle Beach to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Myrtle Beach and San Francisco flights
Browse other Myrtle Beach and San Francisco flight options. Last updated on August 14, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Top 3 airlines flying from Myrtle Beach to San Francisco
Discover the top 3 airlines that operate flights from Myrtle Beach to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$326 | Average$472 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$362 | Average$483 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$382 | Average$533 | FlexibilityNo cancel fee | On-time63% |