$202+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SFO
Jun 13 — Jun 201
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to San Francisco
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Cheapest flights from Myrtle Beach to San FranciscoExplore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 am
MYR
- SFO
1 stop8h 25m
Southwest
Tue 9/2910:30 pm
SFO
- MYR
1 stop8h 35m
Southwest
Deal found 5/11![Southwest logo]()
$403
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:00 am
MYR
- SFO
1 stop9h 40m
Southwest
Tue 6/305:30 am
SFO
- MYR
1 stop10h 05m
Southwest
Deal found 5/12![Southwest logo]()
$408
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:24 am
MYR
- SFO
1 stop8h 55m
United Airlines
Wed 6/1011:30 pm
SFO
- MYR
1 stop8h 06m
United Airlines
Deal found 5/10![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:10 pm
MYR
- SFO
2 stops11h 20m
Southwest
Wed 7/225:50 am
SFO
- MYR
2 stops11h 40m
Southwest
Deal found 5/12![Southwest logo]()
$413
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:55 am
MYR
- SFO
1 stop8h 35m
Southwest
Wed 6/105:00 am
SFO
- MYR
2 stops10h 35m
Southwest
Deal found 5/10![Southwest logo]()
$414
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:39 pm
MYR
- SFO
1 stop9h 42m
American Airlines
Mon 6/155:00 am
SFO
- MYR
1 stop7h 32m
American Airlines
Deal found 5/12![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:15 pm
MYR
- SFO
1 stop7h 55m
Southwest
Thu 6/116:45 am
SFO
- MYR
2 stops11h 55m
Southwest
Deal found 5/13![Southwest logo]()
$420
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:16 pm
MYR
- SFO
1 stop8h 51m
American Airlines
Wed 7/155:29 am
SFO
- MYR
1 stop7h 09m
American Airlines
Deal found 5/13![American Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:17 pm
MYR
- SFO
1 stop9h 32m
American Airlines
Mon 6/155:00 am
SFO
- MYR
1 stop7h 32m
American Airlines
Deal found 5/12![American Airlines logo]()
$441
Best flights from Myrtle Beach to San FranciscoDiscover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:00 am
MYR
- SFO
1 stop8h 25m
Southwest
Tue 9/2910:30 pm
SFO
- MYR
1 stop8h 35m
Southwest
Deal found 5/11![Southwest logo]()
$403
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/154:16 pm
MYR
- SFO
1 stop9h 32m
American Airlines
Wed 7/225:29 am
SFO
- MYR
1 stop7h 09m
American Airlines
Deal found 5/12![American Airlines logo]()
$403
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:24 am
MYR
- SFO
1 stop8h 55m
United Airlines
Wed 6/1011:30 pm
SFO
- MYR
1 stop8h 06m
United Airlines
Deal found 5/10![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:55 am
MYR
- SFO
1 stop8h 35m
Southwest
Wed 6/105:00 am
SFO
- MYR
2 stops10h 35m
Southwest
Deal found 5/10![Southwest logo]()
$414
This American Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:16 pm
MYR
- SFO
1 stop8h 51m
American Airlines
Wed 7/155:29 am
SFO
- MYR
1 stop7h 09m
American Airlines
Deal found 5/13![American Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:15 pm
MYR
- SFO
1 stop7h 55m
Southwest
Thu 6/116:45 am
SFO
- MYR
2 stops11h 55m
Southwest
Deal found 5/13![Southwest logo]()
$420
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:15 am
MYR
- SFO
2 stops11h 40m
Southwest
Tue 6/165:30 am
SFO
- MYR
2 stops12h 00m
Southwest
Deal found 5/10![Southwest logo]()
$466
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:30 am
MYR
- SFO
1 stop8h 40m
Southwest
Sun 8/2310:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 5/13![Southwest logo]()
$467
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/132:00 pm
MYR
- SFO
1 stop9h 20m
Southwest
Sun 6/215:30 am
SFO
- MYR
2 stops13h 00m
Southwest
Deal found 5/11![Southwest logo]()
$508
Last-minute flights from Myrtle Beach to San FranciscoDiscover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated May 14, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated May 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:24 am
MYR
- SFO
1 stop8h 55m
United Airlines
Wed 6/1011:30 pm
SFO
- MYR
1 stop8h 06m
United Airlines
Deal found 5/10![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/411:55 am
MYR
- SFO
1 stop8h 35m
Southwest
Wed 6/105:00 am
SFO
- MYR
2 stops10h 35m
Southwest
Deal found 5/10![Southwest logo]()
$414
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:15 pm
MYR
- SFO
1 stop7h 55m
Southwest
Thu 6/116:45 am
SFO
- MYR
2 stops11h 55m
Southwest
Deal found 5/13![Southwest logo]()
$420
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:39 pm
MYR
- SFO
1 stop9h 42m
American Airlines
Mon 6/155:00 am
SFO
- MYR
1 stop7h 32m
American Airlines
Deal found 5/12![American Airlines logo]()
$415
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1111:55 am
MYR
- SFO
2 stops11h 25m
Southwest
Mon 6/156:10 pm
SFO
- MYR
2 stops12h 40m
Southwest
Deal found 5/12![Southwest logo]()
$451
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:57 pm
MYR
- SFO
1 stop7h 48m
Delta
Tue 6/166:00 am
SFO
- MYR
1 stop7h 40m
Delta
Deal found 5/10![Delta logo]()
$435
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/124:17 pm
MYR
- SFO
1 stop9h 32m
American Airlines
Mon 6/155:00 am
SFO
- MYR
1 stop7h 32m
American Airlines
Deal found 5/12![American Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:15 pm
MYR
- SFO
1 stop7h 55m
Southwest
Mon 6/156:10 pm
SFO
- MYR
2 stops12h 40m
Southwest
Deal found 5/12![Southwest logo]()
$446
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:00 am
MYR
- SFO
1 stop9h 40m
Southwest
Tue 6/305:30 am
SFO
- MYR
1 stop10h 05m
Southwest
Deal found 5/12![Southwest logo]()
$408
One-way flights from Myrtle Beach to San FranciscoSearch for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
Search for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:39 pm
MYR
- SFO
1 stop8h 51m
American Airlines
Deal found 5/10![American Airlines logo]()
$202
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:22 am
MYR
- SFO
1 stop10h 21m
American Airlines
Deal found 5/12![American Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:45 am
MYR
- SFO
2 stops11h 50m
Southwest
Deal found 5/12![Southwest logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:03 am
MYR
- SFO
1 stop28h 59m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:07 pm
MYR
- SFO
2 stops30h 20m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:30 pm
MYR
- SFO
3 stops53h 48m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$231
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:28 pm
MYR
- SFO
1 stop7h 21m
American Airlines
Deal found 5/11![American Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/242:15 pm
MYR
- SFO
2 stops12h 00m
Southwest
Deal found 5/11![Southwest logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/146:28 pm
MYR
- SFO
2 stops43h 00m
Frontier
Deal found 5/10![Frontier logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/125:58 pm
MYR
- SFO
3 stops43h 49m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:34 pm
MYR
- SFO
3 stops43h 49m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$257
Find flight deals from Myrtle Beach to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $403 (Southwest) |
One-way from | $202 (American Airlines) |
Popular in | November |
Cheapest in | October |
Average price | $555 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 9/15
11:00 am-4:25 pm
1 stop8h 25m
San Francisco
Tue 9/29
10:30 pm-10:05 am
1 stop8h 35m
$403
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Wed 7/15
4:16 pm-10:48 pm
1 stop9h 32m
San Francisco
Wed 7/22
5:29 am-3:38 pm
1 stop7h 09m
$403
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Thu 6/4
11:24 am-5:19 pm
1 stop8h 55m
San Francisco
Wed 6/10
11:30 pm-10:36 am
1 stop8h 06m
$409
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Thu 6/4
11:55 am-5:30 pm
1 stop8h 35m
San Francisco
Wed 6/10
5:00 am-6:35 pm
2 stops10h 35m
$414
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Mon 6/8
7:15 pm-12:10 am
1 stop7h 55m
San Francisco
Thu 6/11
6:45 am-9:40 pm
2 stops11h 55m
$420
Quickest round-trip
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Fri 7/10
4:16 pm-10:07 pm
1 stop8h 51m
San Francisco
Wed 7/15
5:29 am-3:38 pm
1 stop7h 09m
$435
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Fri 6/12
5:15 am-1:55 pm
2 stops11h 40m
San Francisco
Tue 6/16
5:30 am-8:30 pm
2 stops12h 00m
$466
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Sun 8/16
7:30 am-1:10 pm
1 stop8h 40m
San Francisco
Sun 8/23
10:30 pm-10:15 am
1 stop8h 45m
$467
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Sat 6/13
2:00 pm-8:20 pm
1 stop9h 20m
San Francisco
Sun 6/21
5:30 am-9:30 pm
2 stops13h 00m
$508
Cheapest one-way
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 9/22
4:26 pm-12:12 am
1 stop10h 46m
$202
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.
MYR-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Francisco
What is the cheapest month to book a flight from Myrtle Beach to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $390). Flying from Myrtle Beach to San Francisco in November is currently the most expensive (average of $691). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 14, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Overall
8.0
Comfort
8.0
Boarding
8.1
Crew
8.6
Entertainment
7.5
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Top 3 airlines flying from Myrtle Beach to San Francisco
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| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$306 | Average$466 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$472 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$382 | Average$587 | FlexibilityNo cancel fee | On-time63% |