$169+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SFO
Aug 6 — Aug 131
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to San Francisco
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Best
Last-minute
One-way
Cheapest flights from Myrtle Beach to San FranciscoExplore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 7, 2026.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:59 pm
MYR
- SFO
1 stop7h 58m
Delta
Sat 10/310:59 pm
SFO
- MYR
1 stop8h 38m
Delta
Deal found 7/2![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:50 am
MYR
- SFO
1 stop8h 05m
Southwest
Sat 10/311:40 pm
SFO
- MYR
2 stops12h 45m
Southwest
Deal found 7/2![Southwest logo]()
$342
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:55 am
MYR
- SFO
1 stop7h 30m
Southwest
Sat 8/2210:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 7/3![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:00 am
MYR
- SFO
1 stop8h 25m
Southwest
Tue 8/1811:05 pm
SFO
- MYR
2 stops11h 45m
Southwest
Deal found 7/6![Southwest logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:49 pm
MYR
- SFO
2 stops21h 36m
Multiple Airlines
Fri 8/1412:18 pm
SFO
- MYR
1 stop23h 25m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 am
MYR
- SFO
1 stop7h 40m
Southwest
Sat 9/1910:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 7/4![Southwest logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:09 pm
MYR
- SFO
2 stops11h 09m
Multiple Airlines
Fri 8/712:18 pm
SFO
- MYR
1 stop23h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$409
Best flights from Myrtle Beach to San FranciscoDiscover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 7, 2026.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:59 pm
MYR
- SFO
1 stop7h 58m
Delta
Sat 10/310:59 pm
SFO
- MYR
1 stop8h 38m
Delta
Deal found 7/2![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:25 pm
MYR
- SFO
2 stops11h 50m
Southwest
Sat 10/36:25 pm
SFO
- MYR
2 stops13h 25m
Southwest
Deal found 7/2![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:00 am
MYR
- SFO
1 stop10h 14m
American Airlines
Sun 8/231:14 pm
SFO
- MYR
1 stop7h 36m
American Airlines
Deal found 7/2![American Airlines logo]()
$466
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:55 am
MYR
- SFO
1 stop7h 30m
Southwest
Sat 8/2211:05 pm
SFO
- MYR
2 stops12h 05m
Southwest
Deal found 7/3![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:00 am
MYR
- SFO
1 stop8h 25m
Southwest
Tue 8/1811:05 pm
SFO
- MYR
2 stops11h 45m
Southwest
Deal found 7/6![Southwest logo]()
$389
This Southwest deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 am
MYR
- SFO
1 stop7h 40m
Southwest
Sat 9/1910:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 7/4![Southwest logo]()
$402
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:40 am
MYR
- SFO
2 stops10h 30m
Southwest
Fri 8/75:35 am
SFO
- MYR
2 stops11h 05m
Southwest
Deal found 7/2![Southwest logo]()
$430
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:15 am
MYR
- SFO
2 stops11h 10m
Southwest
Tue 8/1810:30 pm
SFO
- MYR
1 stop8h 35m
Southwest
Deal found 7/5![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:25 am
MYR
- SFO
1 stop8h 20m
Southwest
Tue 8/411:05 pm
SFO
- MYR
2 stops11h 45m
Southwest
Deal found 7/3![Southwest logo]()
$485
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:40 am
MYR
- SFO
1 stop9h 20m
Southwest
Sat 8/1510:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 7/6![Southwest logo]()
$488
Last-minute flights from Myrtle Beach to San FranciscoDiscover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated July 7, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Francisco. Data last updated July 7, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/64:09 pm
MYR
- SFO
2 stops11h 09m
Multiple Airlines
Fri 8/712:18 pm
SFO
- MYR
1 stop23h 25m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:15 pm
MYR
- SFO
1 stop8h 25m
American Airlines
Fri 8/75:30 am
SFO
- MYR
1 stop7h 07m
American Airlines
Deal found 7/2![American Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:40 am
MYR
- SFO
2 stops10h 30m
Southwest
Fri 8/75:35 am
SFO
- MYR
2 stops11h 05m
Southwest
Deal found 7/2![Southwest logo]()
$430
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:23 pm
MYR
- SFO
2 stops32h 55m
Multiple Airlines
Fri 8/1412:18 pm
SFO
- MYR
1 stop23h 25m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$418
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:00 am
MYR
- SFO
1 stop8h 25m
Southwest
Tue 8/1811:05 pm
SFO
- MYR
2 stops11h 45m
Southwest
Deal found 7/6![Southwest logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:49 pm
MYR
- SFO
2 stops21h 36m
Multiple Airlines
Fri 8/1412:18 pm
SFO
- MYR
1 stop23h 25m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$392
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:55 am
MYR
- SFO
1 stop7h 30m
Southwest
Sat 8/2210:30 pm
SFO
- MYR
1 stop8h 45m
Southwest
Deal found 7/3![Southwest logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:07 am
MYR
- SFO
1 stop28h 55m
Multiple Airlines
Sat 8/2211:00 am
SFO
- MYR
2 stops20h 05m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$434
One-way flights from Myrtle Beach to San FranciscoSearch for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
Search for one-way flight options from Myrtle Beach to San Francisco. Find affordable one-way fares based on user searches. Data last updated July 7, 2026.
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:08 am
MYR
- SFO
1 stop10h 31m
American Airlines
Deal found 7/3![American Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:30 pm
MYR
- SFO
2 stops25h 15m
Frontier
Deal found 7/3![Frontier logo]()
$185
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:14 pm
MYR
- SFO
1 stop10h 04m
American Airlines
Deal found 7/3![American Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/18:46 am
MYR
- SFO
2 stops18h 37m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$195
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:10 pm
MYR
- SFO
2 stops11h 20m
Southwest
Deal found 7/2![Southwest logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:01 pm
MYR
- SFO
3 stops33h 44m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$221
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:16 pm
MYR
- SFO
1 stop9h 32m
American Airlines
Deal found 7/2![American Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:21 pm
MYR
- SFO
2 stops19h 27m
Multiple Airlines
Deal found 7/4![Multiple Airlines logo]()
$260
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/314:16 pm
MYR
- SFO
1 stop8h 51m
American Airlines
Deal found 7/6![American Airlines logo]()
$270
Find flight deals from Myrtle Beach to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $337 (Delta) |
One-way from | $169 (American Airlines) |
Popular in | April |
Cheapest in | October |
Average price | $488 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 9/29
6:59 pm-11:57 pm
1 stop7h 58m
San Francisco
Sat 10/3
10:59 pm-10:37 am
1 stop8h 38m
$337
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 9/29
2:25 pm-11:15 pm
2 stops11h 50m
San Francisco
Sat 10/3
6:25 pm-10:50 am
2 stops13h 25m
$347
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Sat 8/15
11:55 am-4:25 pm
1 stop7h 30m
San Francisco
Sat 8/22
11:05 pm-2:10 pm
2 stops12h 05m
$378
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 8/11
11:00 am-4:25 pm
1 stop8h 25m
San Francisco
Tue 8/18
11:05 pm-1:50 pm
2 stops11h 45m
$389
Quickest round-trip
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Fri 9/11
8:10 am-12:50 pm
1 stop7h 40m
San Francisco
Sat 9/19
10:30 pm-10:15 am
1 stop8h 45m
$402
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Thu 8/6
6:40 am-2:10 pm
2 stops10h 30m
San Francisco
Fri 8/7
5:35 am-7:40 pm
2 stops11h 05m
$430
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Sun 8/16
5:00 am-12:14 pm
1 stop10h 14m
San Francisco
Sun 8/23
1:14 pm-11:50 pm
1 stop7h 36m
$466
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Tue 8/4
8:15 am-4:25 pm
2 stops11h 10m
San Francisco
Tue 8/18
10:30 pm-10:05 am
1 stop8h 35m
$472
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Wed 7/22
10:25 am-3:45 pm
1 stop8h 20m
San Francisco
Tue 8/4
11:05 pm-1:50 pm
2 stops11h 45m
$485
Myrtle BeachSan Francisco
MYR - SFO
MYRSFO
Myrtle Beach Intl
Mon 8/10
6:40 am-1:00 pm
1 stop9h 20m
San Francisco
Sat 8/15
10:30 pm-10:15 am
1 stop8h 45m
$488
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in July.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.
MYR-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Francisco
What is the cheapest month to book a flight from Myrtle Beach to San Francisco?
Currently, October is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $390). Flying from Myrtle Beach to San Francisco in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Myrtle Beach to San Francisco?
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated July 7, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Redwood City
Rancho Cordova
Roseville
Cupertino
Emeryville
Newark
San Bruno
Watsonville
Hayward
San Ramon
San Carlos
Daly City
Turlock
Vallejo
San Lorenzo
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Alternative routes for Myrtle Beach to San Francisco
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Search flights from Myrtle Beach to San Francisco by cabin class
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Myrtle Beach and San Francisco flights
Browse other Myrtle Beach and San Francisco flight options. Last updated on July 7, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on July 7, 2026.
Popular flight searches
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 7, 2026.
Top 3 airlines flying from Myrtle Beach to San Francisco
Discover the top 3 airlines that operate flights from Myrtle Beach to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$312 | Average$459 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$466 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$382 | Average$587 | FlexibilityNo cancel fee | On-time63% |