San Francisco

$150+ Cheap flights from Myrtle Beach to San Francisco (MYR - SFO)

MYR — SFO
Dec 13 — Dec 201
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1. Tell us where you want to go

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2. Select your favorite providers

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3. Compare prices and book

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Cheap flight deals from Myrtle Beach to San Francisco

Cheapest flights from Myrtle Beach to San Francisco

Thu 12/1011:26 am -
1 stop9h 48m
Mon 12/149:59 pm -
1 stop9h 08m
Deal found 11/11$443
Thu 12/103:25 pm -
2 stops11h 30m
Mon 12/149:25 pm -
1 stop9h 40m
Deal found 11/11$448
Wed 12/910:52 am -
1 stop9h 32m
Sun 12/1311:59 pm -
1 stop7h 08m
Deal found 11/11$460
Thu 12/103:25 pm -
2 stops11h 30m
Mon 1/49:25 pm -
1 stop9h 40m
Deal found 11/10$463
Thu 12/106:47 am -
1 stop8h 40m
Mon 1/46:51 pm -
2 stops10h 44m
Deal found 11/10$471
Thu 12/106:47 am -
1 stop8h 40m
Sun 12/131:27 pm -
1 stop7h 31m
Deal found 11/11$475
Thu 12/103:25 pm -
2 stops11h 30m
Sun 12/135:15 am -
2 stops12h 05m
Deal found 11/11$485

Find flight deals from Myrtle Beach to San Francisco

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$393
(American Airlines)

One-way from

$150
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$642
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
From Myrtle Beach Intl to San Francisco
One-way flight from Myrtle Beach Intl to San Francisco
Highest demand for flights based on searches. 8% potential increase in price ($54 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
Average for round-trip flights in November 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Myrtle Beach to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Tue 12/8

6:59 pm-11:55 pm

1 stop7h 56m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$197

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 12/3

2:18 pm-9:44 pm

1 stop10h 26m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$222

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Mon 12/7

6:57 pm-11:59 pm

1 stop8h 02m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$222

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 2/18

7:18 pm-5:01 pm

3 stops48h 43m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$232

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Fri 12/4

5:08 am-12:27 pm

1 stop10h 19m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$236

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Thu 2/18

4:10 pm-11:26 pm

2 stops10h 16m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$241

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Sat 12/5

11:26 am-11:43 pm

2 stops15h 17m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$245

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Sun 12/6

6:57 pm-11:59 pm

1 stop8h 02m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$320

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Sat 11/21

9:53 am-11:01 am

2 stops52h 08m

San Francisco

Wed 12/31

12:00 am-3:00 am

Nonstop0h 00m

$385

Myrtle BeachSan Francisco

MYR Myrtle Beach Intl - SFO San Francisco

MYRSFO

Myrtle Beach Intl

Wed 1/6

5:12 pm-10:53 pm

1 stop8h 41m

San Francisco

Sat 1/9

9:49 pm-9:44 am

1 stop8h 55m

$393

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Myrtle Beach to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Francisco in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Myrtle Beach with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Francisco

What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $423). Flying from Myrtle Beach to San Francisco in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Francisco

Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Myrtle Beach to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Comfort

8.0

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
10.0
Excellent

Walter,May 2026

LAS - BUR

Short but excellent flight. Everyone was friendly and professional it was a great flight!

Related info for your journey

  • How long is the flight from Myrtle Beach to San Francisco?

    A quick flight from Myrtle Beach to San Francisco can take about 8h 41m. American Airlines provides one of the quickest options available for as low as $393. Myrtle Beach and San Francisco are separated by a distance of 2431 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Myrtle Beach to San Francisco round-trip?

    Currently priced at $336, Southwest will fly you from Myrtle Beach to San Francisco and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $359 and $369, respectively. You may be able to fly from Myrtle Beach to San Francisco for 39% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Myrtle Beach to San Francisco one-way?

    $152 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and Southwest, with prices starting from $179 and $191, respectively.

  • Can I find deals for flights from Myrtle Beach to San Francisco that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Francisco.

  • Can I find deals for business class flights from Myrtle Beach to San Francisco?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Francisco?

    Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to San Francisco (average of $423). Flying from Myrtle Beach to San Francisco in April is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
San Carlos
Sunnyvale
Turlock
Morgan Hill
San Ramon
Milpitas

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Myrtle Beach to San Francisco

Top 3 airlines flying from Myrtle Beach to San Francisco

AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$336Average$587FlexibilityNo cancel feeOn-time63%
DeltaCheapest$359Average$542FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$369Average$488FlexibilityNo cancel feeOn-time71%

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