$134+ Cheap flights from Greenville to San Diego (GSP - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — SAN
Sep 11 — Sep 181
Round-trip
1 adult, Economy
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Find cheap flights from Greenville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Diego
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Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:20 pm -
1 stop6h 45m
Tue 10/1310:40 pm -
1 stop11h 00m
Deal found 8/11![Southwest logo]()
$272
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:40 pm -
1 stop6h 50m
Tue 10/1310:40 pm -
1 stop11h 00m
Deal found 8/11![Southwest logo]()
$291
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
1 stop8h 13m
Mon 11/99:50 pm -
1 stop8h 57m
Deal found 8/11![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:10 am -
1 stop10h 10m
Thu 11/1210:00 pm -
1 stop9h 11m
Deal found 8/10![Delta logo]()
$305
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:50 pm -
1 stop6h 30m
Thu 11/128:00 am -
2 stops9h 10m
Deal found 8/10![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop7h 25m
Tue 9/1512:52 pm -
1 stop7h 03m
Deal found 8/11![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:05 am -
1 stop9h 25m
Fri 11/139:55 pm -
1 stop9h 15m
Deal found 8/11![Southwest logo]()
$329
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:28 pm -
1 stop6h 30m
Fri 9/116:15 am -
1 stop7h 19m
Deal found 8/8![American Airlines logo]()
$334
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/165:25 pm -
1 stop7h 21m
Mon 10/199:25 pm -
1 stop9h 19m
Deal found 8/10![American Airlines logo]()
$336
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:20 pm -
1 stop8h 40m
Wed 9/26:15 am -
1 stop9h 30m
Deal found 8/11![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:50 pm -
1 stop6h 30m
Sat 11/149:55 pm -
1 stop9h 15m
Deal found 8/10![Southwest logo]()
$359
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/55:46 pm -
1 stop7h 55m
Fri 10/910:30 pm -
1 stop8h 28m
Deal found 8/11![United Airlines logo]()
$446
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:35 am -
1 stop28h 13m
Thu 9/36:25 am -
2 stops35h 15m
Deal found 8/11![Multiple Airlines logo]()
$478
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am -
1 stop8h 09m
Tue 9/112:32 pm -
1 stop7h 27m
Deal found 8/11![Delta logo]()
$358
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:40 pm -
1 stop6h 50m
Tue 10/139:15 am -
2 stops8h 45m
Deal found 8/10![Southwest logo]()
$372
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/263:30 pm -
2 stops8h 35m
Tue 9/299:35 am -
2 stops8h 20m
Deal found 8/7![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/294:33 pm -
2 stops10h 56m
Tue 9/19:05 pm -
1 stop10h 32m
Deal found 8/11![United Airlines logo]()
$473
This Southwest deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/257:05 am -
2 stops7h 45m
Sat 1/29:15 pm -
2 stops11h 55m
Deal found 8/8![Southwest logo]()
$463
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:40 am -
2 stops12h 30m
Wed 9/28:35 am -
2 stops9h 20m
Deal found 8/11![Southwest logo]()
$474
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated August 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:20 pm -
1 stop8h 40m
Wed 9/26:15 am -
1 stop9h 30m
Deal found 8/11![Delta logo]()
$358
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/3010:35 am -
1 stop28h 13m
Sat 9/53:45 pm -
2 stops24h 54m
Deal found 8/11![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:19 pm -
1 stop20h 20m
Sat 9/53:45 pm -
2 stops24h 54m
Deal found 8/11![Multiple Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:33 pm -
1 stop7h 01m
Mon 9/710:40 pm -
1 stop7h 55m
Deal found 8/10![United Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:19 pm -
1 stop20h 20m
Tue 9/84:36 pm -
2 stops37h 51m
Deal found 8/11![Multiple Airlines logo]()
$356
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:00 am -
1 stop8h 50m
Sun 9/610:40 pm -
1 stop7h 56m
Deal found 8/10![United Airlines logo]()
$341
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:28 pm -
1 stop6h 30m
Fri 9/116:15 am -
1 stop7h 19m
Deal found 8/8![American Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:00 am -
1 stop7h 25m
Tue 9/1512:52 pm -
1 stop7h 03m
Deal found 8/11![Delta logo]()
$323
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:30 pm -
1 stop6h 20m
Deal found 8/10![Southwest logo]()
$134
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:00 am -
1 stop7h 25m
Deal found 8/10![Delta logo]()
$149
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:50 pm -
1 stop6h 30m
Deal found 8/9![Southwest logo]()
$153
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:00 am -
1 stop8h 50m
Deal found 8/9![United Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:19 pm -
1 stop20h 20m
Deal found 8/10![Breeze Airways logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:34 pm -
3 stops33h 17m
Deal found 8/10![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:24 pm -
3 stops48h 36m
Deal found 8/10![Multiple Airlines logo]()
$178
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:33 pm -
2 stops10h 56m
Deal found 8/10![United Airlines logo]()
$180
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2511:20 am -
1 stop6h 35m
Deal found 8/9![Southwest logo]()
$189
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $272 (Southwest) |
One-way from | $134 (Southwest) |
Popular in | June |
Cheapest in | August |
Average price | $362 |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 8/29
5:20 pm-11:00 pm
1 stop8h 40m
San Diego
Wed 9/2
6:15 am-6:45 pm
1 stop9h 30m
$358
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 8/29
6:00 am-11:09 am
1 stop8h 09m
San Diego
Tue 9/1
12:32 pm-10:59 pm
1 stop7h 27m
$358
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Mon 11/9
8:50 pm-12:20 am
1 stop6h 30m
San Diego
Sat 11/14
9:55 pm-10:10 am
1 stop9h 15m
$359
Quickest round-trip
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Thu 10/8
8:40 pm-12:30 am
1 stop6h 50m
San Diego
Tue 10/13
9:15 am-9:00 pm
2 stops8h 45m
$372
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 9/26
3:30 pm-9:05 pm
2 stops8h 35m
San Diego
Tue 9/29
9:35 am-8:55 pm
2 stops8h 20m
$379
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Mon 10/5
5:46 pm-10:41 pm
1 stop7h 55m
San Diego
Fri 10/9
10:30 pm-9:58 am
1 stop8h 28m
$446
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Fri 12/25
7:05 am-11:50 am
2 stops7h 45m
San Diego
Sat 1/2
9:15 pm-12:10 pm
2 stops11h 55m
$463
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Sat 8/29
4:33 pm-12:29 am
2 stops10h 56m
San Diego
Tue 9/1
9:05 pm-10:37 am
1 stop10h 32m
$473
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Fri 8/28
8:40 am-6:10 pm
2 stops12h 30m
San Diego
Wed 9/2
8:35 am-8:55 pm
2 stops9h 20m
$474
GreenvilleSan Diego
GSP Greenville - SAN San Diego
GSPSAN
Greenville
Thu 8/27
10:35 am-11:48 am
1 stop28h 13m
San Diego
Thu 9/3
6:25 am-8:40 pm
2 stops35h 15m
$478
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
GSP-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Greenville to San Diego
How far ahead should I book a flight from Greenville to San Diego?
The price you pay for your flight from Greenville to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 66 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Greenville to San Diego?
Currently, August is the cheapest month in which you can book a flight from Greenville to San Diego (average of $362). Flying from Greenville to San Diego in June is currently the most expensive (average of $586). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Greenville to San Diego?
Airfare is below average for this route at the moment.
Greenville to San Diego flights typically cost between $342 and $453 in October.The cheapest round-trip price found within the last 5 days was $272 on Southwest (Oct 7-Oct 13).
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated August 12, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Greenville to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Comfort
8.0
Crew
8.6
Boarding
8.1
Entertainment
7.5
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
Coronado
San Ysidro
La Mesa
Santee
Julian
Lemon Grove
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Greenville and San Diego flights
Browse other Greenville and San Diego flight options. Last updated on August 12, 2026.
Other flights from Greenville
Browse through other flights departing from Greenville. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 12, 2026.
Top 4 airlines flying from Greenville to San Diego
Discover the top 4 airlines that operate flights from Greenville to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$298 | Average$466 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$305 | Average$511 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$312 | Average$466 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$312 | Average$477 | FlexibilityNo cancel fee | On-time71% |