$198+ Cheap flights from San Diego to Greenville (SAN - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — GSP
Jun 30 — Jul 71
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to Greenville
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Best
Last-minute
One-way
Cheapest flights from San Diego to GreenvilleExplore the most affordable flight options available from San Diego to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
Explore the most affordable flight options available from San Diego to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 31, 2026.
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:17 pm
SAN
- GSP
1 stop8h 58m
Delta
Thu 8/135:20 pm
GSP
- SAN
1 stop8h 40m
Delta
Deal found 5/30![Delta logo]()
$378
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:30 pm
SAN
- GSP
1 stop8h 32m
Delta
Wed 8/125:20 pm
GSP
- SAN
1 stop8h 40m
Delta
Deal found 5/30![Delta logo]()
$382
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:15 am
SAN
- GSP
1 stop7h 17m
American Airlines
Tue 6/305:15 am
GSP
- SAN
1 stop6h 49m
American Airlines
Deal found 5/25![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:40 pm
SAN
- GSP
1 stop8h 30m
Southwest
Wed 8/121:20 pm
GSP
- SAN
1 stop9h 15m
Southwest
Deal found 5/28![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:40 pm
SAN
- GSP
1 stop8h 25m
Southwest
Sat 8/223:30 pm
GSP
- SAN
1 stop7h 25m
Southwest
Deal found 5/29![Southwest logo]()
$394
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:17 pm
SAN
- GSP
1 stop8h 58m
Delta
Tue 8/115:20 pm
GSP
- SAN
1 stop8h 40m
Delta
Deal found 5/30![Delta logo]()
$410
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:05 pm
SAN
- GSP
1 stop10h 32m
United Airlines
Tue 7/285:10 pm
GSP
- SAN
1 stop7h 14m
United Airlines
Deal found 5/25![United Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:25 pm
SAN
- GSP
1 stop8h 30m
United Airlines
Tue 7/146:10 am
GSP
- SAN
1 stop8h 11m
United Airlines
Deal found 5/27![United Airlines logo]()
$425
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Sun 7/197:30 pm
GSP
- SAN
1 stop7h 00m
Southwest
Deal found 5/27![Southwest logo]()
$430
Best flights from San Diego to GreenvilleDiscover carefully curated flight deals from San Diego to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
Discover carefully curated flight deals from San Diego to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 31, 2026.
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:40 pm
SAN
- GSP
1 stop8h 25m
Southwest
Sat 8/223:30 pm
GSP
- SAN
1 stop7h 25m
Southwest
Deal found 5/29![Southwest logo]()
$394
This American Airlines deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:15 am
SAN
- GSP
1 stop6h 21m
American Airlines
Tue 7/148:01 pm
GSP
- SAN
1 stop6h 58m
American Airlines
Deal found 5/27![American Airlines logo]()
$425
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:30 pm
SAN
- GSP
1 stop8h 32m
Delta
Sat 8/156:00 am
GSP
- SAN
1 stop6h 26m
Delta
Deal found 5/30![Delta logo]()
$446
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:30 am
SAN
- GSP
2 stops8h 45m
Southwest
Tue 7/287:00 am
GSP
- SAN
2 stops9h 45m
Southwest
Deal found 5/25![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:35 am
SAN
- GSP
2 stops9h 20m
Southwest
Sun 7/197:30 pm
GSP
- SAN
1 stop7h 00m
Southwest
Deal found 5/27![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:30 am
SAN
- GSP
2 stops8h 45m
Southwest
Sat 7/1812:50 pm
GSP
- SAN
1 stop7h 05m
Southwest
Deal found 5/29![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:20 am
SAN
- GSP
2 stops8h 55m
Southwest
Sun 7/197:30 pm
GSP
- SAN
1 stop7h 00m
Southwest
Deal found 5/27![Southwest logo]()
$472
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:45 am
SAN
- GSP
2 stops8h 15m
Southwest
Tue 6/307:00 am
GSP
- SAN
1 stop6h 15m
Southwest
Deal found 5/25![Southwest logo]()
$475
Last-minute flights from San Diego to GreenvilleDiscover last-minute flight deals from San Diego to Greenville. Data last updated May 31, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Greenville. Data last updated May 31, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:15 am
SAN
- GSP
1 stop7h 17m
American Airlines
Tue 6/235:25 pm
GSP
- SAN
1 stop8h 14m
American Airlines
Deal found 5/28![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:15 am
SAN
- GSP
1 stop7h 17m
American Airlines
Tue 6/305:15 am
GSP
- SAN
1 stop6h 49m
American Airlines
Deal found 5/25![American Airlines logo]()
$383
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/231:02 pm
SAN
- GSP
1 stop7h 57m
Delta
Mon 6/295:16 pm
GSP
- SAN
1 stop8h 44m
Delta
Deal found 5/30![Delta logo]()
$431
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:59 am
SAN
- GSP
1 stop8h 57m
American Airlines
Thu 6/257:55 pm
GSP
- SAN
1 stop7h 04m
American Airlines
Deal found 5/30![American Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:45 am
SAN
- GSP
2 stops8h 15m
Southwest
Tue 6/307:00 am
GSP
- SAN
1 stop6h 15m
Southwest
Deal found 5/25![Southwest logo]()
$475
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:45 am
SAN
- GSP
2 stops8h 15m
Southwest
Mon 6/297:05 am
GSP
- SAN
1 stop6h 10m
Southwest
Deal found 5/30![Southwest logo]()
$491
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:45 am
SAN
- GSP
2 stops8h 15m
Southwest
Thu 6/256:50 pm
GSP
- SAN
1 stop6h 35m
Southwest
Deal found 5/30![Southwest logo]()
$527
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:00 am
SAN
- GSP
1 stop9h 20m
Delta
Mon 6/295:16 pm
GSP
- SAN
1 stop8h 44m
Delta
Deal found 5/30![Delta logo]()
$533
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:40 pm
SAN
- GSP
1 stop10h 35m
Southwest
Mon 7/66:50 pm
GSP
- SAN
1 stop6h 40m
Southwest
Deal found 5/30![Southwest logo]()
$508
One-way flights from San Diego to GreenvilleSearch for one-way flight options from San Diego to Greenville. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
Search for one-way flight options from San Diego to Greenville. Find affordable one-way fares based on user searches. Data last updated May 31, 2026.
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:05 pm
SAN
- GSP
1 stop7h 10m
American Airlines
Deal found 5/29![American Airlines logo]()
$198
This Delta deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1210:30 pm
SAN
- GSP
1 stop9h 03m
Delta
Deal found 5/26![Delta logo]()
$202
This Southwest deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:55 am
SAN
- GSP
2 stops8h 40m
Southwest
Deal found 5/29![Southwest logo]()
$203
This American Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1911:00 pm
SAN
- GSP
1 stop8h 17m
American Airlines
Deal found 5/29![American Airlines logo]()
$213
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:35 am
SAN
- GSP
2 stops8h 50m
Southwest
Deal found 5/26![Southwest logo]()
$216
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/197:41 pm
SAN
- GSP
2 stops11h 10m
United Airlines
Deal found 5/29![United Airlines logo]()
$218
This United Airlines deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:45 pm
SAN
- GSP
1 stop9h 03m
United Airlines
Deal found 5/29![United Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:50 pm
SAN
- GSP
1 stop12h 35m
Southwest
Deal found 5/26![Southwest logo]()
$239
This deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:40 am
SAN
- GSP
1 stop7h 22m
United Airlines
Deal found 5/28![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:40 am
SAN
- GSP
2 stops9h 10m
Southwest
Deal found 5/30![Southwest logo]()
$275
This deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:01 pm
SAN
- GSP
1 stop6h 57m
United Airlines
Deal found 5/28![United Airlines logo]()
$289
Find flight deals from San Diego to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 31, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $331 (Delta) |
One-way from | $198 (American Airlines) |
Popular in | February |
Cheapest in | August |
Average price | $432 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
Use the filters below to find and compare flights from San Diego to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Fri 8/14
10:40 pm-10:05 am
1 stop8h 25m
Greenville
Sat 8/22
3:30 pm-7:55 pm
1 stop7h 25m
$394
Quickest round-trip
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 7/9
7:15 am-4:36 pm
1 stop6h 21m
Greenville
Tue 7/14
8:01 pm-11:59 pm
1 stop6h 58m
$425
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 7/23
6:30 am-6:15 pm
2 stops8h 45m
Greenville
Tue 7/28
7:00 am-1:45 pm
2 stops9h 45m
$435
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Fri 8/7
10:30 pm-10:02 am
1 stop8h 32m
Greenville
Sat 8/15
6:00 am-9:26 am
1 stop6h 26m
$446
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Fri 7/10
10:35 am-10:55 pm
2 stops9h 20m
Greenville
Sun 7/19
7:30 pm-11:30 pm
1 stop7h 00m
$472
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 7/13
6:30 am-6:15 pm
2 stops8h 45m
Greenville
Sat 7/18
12:50 pm-4:55 pm
1 stop7h 05m
$472
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 7/16
6:20 am-6:15 pm
2 stops8h 55m
Greenville
Sun 7/19
7:30 pm-11:30 pm
1 stop7h 00m
$472
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Tue 6/23
7:45 am-7:00 pm
2 stops8h 15m
Greenville
Tue 6/30
7:00 am-10:15 am
1 stop6h 15m
$475
Cheapest one-way
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Tue 10/20
7:41 pm-9:51 am
2 stops11h 10m
$203
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 10/12
8:35 am-8:25 pm
2 stops8h 50m
$216
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from San Diego to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Greenville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Diego-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Diego with our price prediction graph.
SAN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Greenville
What is the cheapest month to book a flight from San Diego to Greenville?
Currently, August is the cheapest month in which you can book a flight from San Diego to Greenville (average of $382). Flying from San Diego to Greenville in February is currently the most expensive (average of $1,076). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Greenville?
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 31, 2026.
Read through reviews of airlines operating flights from San Diego to Greenville, such as Southwest,Delta, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Comfort
8.0
Entertainment
7.5
Crew
8.6
Food
7.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
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Alternative routes for San Diego to Greenville
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Complete your trip to Greenville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 31, 2026.
San Diego and Greenville flights
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Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Diego to Greenville
Discover the top 4 airlines that operate flights from San Diego to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 31, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$302 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$312 | Average$492 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$358 | Average$518 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$398 | Average$550 | FlexibilityNo cancel fee | On-time63% |