$218+ Cheap flights from Santa Ana, CA to Greenville (SNA - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
Nov 12 — Nov 191
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Greenville
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Cheapest flights from Santa Ana to GreenvilleExplore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 13, 2026.
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
1 stop6h 42m
Tue 11/172:03 pm -
1 stop8h 07m
Deal found 10/9![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:15 am -
1 stop7h 46m
Thu 10/294:29 pm -
1 stop8h 31m
Deal found 10/8![United Airlines logo]()
$347
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:45 am -
2 stops10h 05m
Wed 12/162:50 pm -
2 stops9h 55m
Deal found 10/9![Southwest logo]()
$379
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:00 pm -
2 stops10h 51m
Thu 11/195:12 pm -
1 stop7h 38m
Deal found 10/8![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:47 am -
1 stop8h 05m
Wed 12/167:05 am -
1 stop10h 37m
Deal found 10/9![American Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:47 am -
1 stop7h 11m
Tue 11/34:29 pm -
1 stop8h 31m
Deal found 10/8![United Airlines logo]()
$435
Best flights from Santa Ana to GreenvilleDiscover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
Discover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 13, 2026.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:15 am -
1 stop7h 46m
Thu 10/294:29 pm -
1 stop8h 31m
Deal found 10/8![United Airlines logo]()
$347
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
2 stops9h 31m
Tue 11/177:51 am -
1 stop9h 12m
Deal found 10/9![American Airlines logo]()
$391
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:25 am -
2 stops9h 40m
Thu 10/298:25 am -
2 stops11h 00m
Deal found 10/8![Southwest logo]()
$512
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/211:34 am -
1 stop7h 25m
Wed 12/164:18 pm -
1 stop8h 57m
Deal found 10/10![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:47 am -
1 stop7h 11m
Tue 11/36:20 am -
2 stops14h 13m
Deal found 10/8![United Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:28 pm -
2 stops12h 34m
Thu 11/124:29 pm -
1 stop8h 31m
Deal found 10/9![United Airlines logo]()
$504
Last-minute flights from Santa Ana to GreenvilleDiscover last-minute flight deals from Santa Ana to Greenville. Data last updated October 13, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Greenville. Data last updated October 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:15 am -
1 stop7h 46m
Thu 10/294:29 pm -
1 stop8h 31m
Deal found 10/8![United Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:47 am -
1 stop7h 11m
Tue 11/34:29 pm -
1 stop8h 31m
Deal found 10/8![United Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:45 am -
1 stop6h 42m
Tue 11/172:03 pm -
1 stop8h 07m
Deal found 10/9![American Airlines logo]()
$305
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:00 pm -
2 stops10h 51m
Thu 11/195:12 pm -
1 stop7h 38m
Deal found 10/8![United Airlines logo]()
$409
One-way flights from Santa Ana to GreenvilleSearch for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
Search for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated October 13, 2026.
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:10 pm -
1 stop11h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$218
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:17 pm -
2 stops15h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![United Airlines logo]()
$223
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/102:00 pm -
1 stop6h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Delta logo]()
$239
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:30 pm -
2 stops12h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![United Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:30 am -
3 stops45h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Multiple Airlines logo]()
$252
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:25 am -
2 stops9h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Southwest logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:30 am -
3 stops45h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/252:00 pm -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![Delta logo]()
$280
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:25 am -
2 stops10h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Southwest logo]()
$295
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/221:10 pm -
1 stop6h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![American Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/241:55 pm -
1 stop5h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Delta logo]()
$309
Find flight deals from Santa Ana to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $305 (American Airlines) |
One-way from | $218 (United Airlines) |
Popular in | February |
Cheapest in | March |
Average price | $643 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Mon 11/16
9:10 pm-11:17 am
1 stop11h 07m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$218
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Mon 11/2
3:17 pm-9:51 am
2 stops15h 34m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$223
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
6:30 pm-9:51 am
2 stops12h 21m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$244
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
7:30 am-8:13 am
3 stops45h 43m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$252
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Tue 12/22
10:25 am-11:20 pm
2 stops9h 55m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$274
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
2:00 pm-11:38 pm
1 stop6h 38m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$280
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
10:25 am-11:25 pm
2 stops10h 00m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$295
Quickest round-trip
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Tue 12/22
1:10 pm-10:33 pm
1 stop6h 23m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$304
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/25
10:51 am-10:03 pm
1 stop8h 12m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$315
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Tue 10/27
8:15 am-7:01 pm
1 stop7h 46m
Greenville
Thu 10/29
4:29 pm-10:00 pm
1 stop8h 31m
$347
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Greenville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
SNA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Greenville
What is the cheapest month to book a flight from Santa Ana, California to Greenville?
Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $389). Flying from Santa Ana, California to Greenville in February is currently the most expensive (average of $887). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Greenville?
Airfare is below average for this route at the moment.
Santa Ana, California to Greenville flights typically cost between $525 and $896 in November.The cheapest round-trip price found within the last 5 days was $305 on American Airlines (Nov 14-Nov 17).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated October 13, 2026.
See what other customers who have flown with United Airlines and American Airlines from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Crew
8.1
Food
6.7
Overall
7.4
Boarding
7.7
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Entertainment
7.1
Comfort
7.3
Crew
8.1
Food
6.7
Overall
7.4
Boarding
7.7
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Entertainment
7.1
Comfort
7.3
Crew
8.1
Food
6.7
Overall
7.4
Boarding
7.7
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on October 13, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Santa Ana to Greenville
Discover the top 2 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$389 | Average$608 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$390 | Average$586 | FlexibilityNo cancel fee | On-time71% |