$153+ Cheap flights from Santa Ana, CA to Greenville (SNA - GSP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
Oct 18 — Oct 251
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Greenville
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Best
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Cheapest flights from Santa Ana to GreenvilleExplore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:10 pm -
1 stop6h 48m
Mon 11/235:17 pm -
1 stop8h 21m
Deal found 9/17![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:42 am -
1 stop8h 23m
Sat 10/108:00 am -
1 stop8h 45m
Deal found 9/15![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:01 pm -
1 stop7h 04m
Tue 10/205:25 pm -
1 stop8h 04m
Deal found 9/15![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:15 am -
1 stop7h 46m
Tue 11/34:29 pm -
1 stop7h 50m
Deal found 9/16![United Airlines logo]()
$415
Best flights from Santa Ana to GreenvilleDiscover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:42 am -
1 stop8h 23m
Sat 10/108:00 am -
1 stop8h 45m
Deal found 9/15![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:47 am -
1 stop7h 11m
Tue 11/32:19 pm -
2 stops10h 41m
Deal found 9/16![United Airlines logo]()
$420
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:00 am -
2 stops7h 50m
Mon 11/236:40 am -
2 stops9h 55m
Deal found 9/17![Southwest logo]()
$523
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:20 pm -
2 stops10h 45m
Sat 10/1011:20 am -
2 stops7h 55m
Deal found 9/15![Southwest logo]()
$538
Last-minute flights from Santa Ana to GreenvilleDiscover last-minute flight deals from Santa Ana to Greenville. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Greenville. Data last updated September 18, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:42 am -
1 stop8h 23m
Sat 10/108:00 am -
1 stop8h 45m
Deal found 9/15![American Airlines logo]()
$353
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:01 pm -
1 stop7h 04m
Tue 10/205:25 pm -
1 stop8h 04m
Deal found 9/15![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/318:15 am -
1 stop7h 46m
Tue 11/34:29 pm -
1 stop7h 50m
Deal found 9/16![United Airlines logo]()
$415
One-way flights from Santa Ana to GreenvilleSearch for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 am -
1 stop7h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$153
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1810:45 am -
1 stop8h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$168
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2812:10 pm -
1 stop6h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$175
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/82:00 pm -
1 stop6h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$196
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:50 am -
2 stops11h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$200
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:40 am -
2 stops11h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![United Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:30 am -
3 stops47h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$207
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:37 am -
1 stop7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$208
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:01 pm -
1 stop7h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:30 am -
3 stops57h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Multiple Airlines logo]()
$255
Find flight deals from Santa Ana to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Delta) |
One-way from | $153 (United Airlines) |
Popular in | February |
Cheapest in | March |
Average price | $628 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Tue 11/17
6:45 am-4:56 pm
1 stop7h 11m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$153
Quickest round-trip
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Fri 1/8
2:00 pm-11:37 pm
1 stop6h 37m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$196
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 11/18
6:50 am-8:58 pm
2 stops11h 08m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$200
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Thu 1/28
8:40 am-11:19 pm
2 stops11h 39m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$201
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Tue 10/6
10:37 am-9:17 pm
1 stop7h 40m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$208
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
12:01 pm-10:05 pm
1 stop7h 04m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$222
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Fri 1/8
7:50 pm-9:51 am
2 stops11h 01m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$256
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 10/7
8:10 am-11:13 pm
2 stops12h 03m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$267
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Mon 10/19
9:00 pm-10:45 am
1 stop10h 45m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$304
Santa AnaGreenville
SNA Santa Ana J. Wayne/Orange Cnty - GSP Greenville
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Thu 10/22
12:01 pm-10:05 pm
1 stop7h 04m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$305
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Greenville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
SNA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Greenville
What is the cheapest month to book a flight from Santa Ana, California to Greenville?
Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $389). Flying from Santa Ana, California to Greenville in February is currently the most expensive (average of $887). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Greenville?
Airfare is below average for this route at the moment.
Santa Ana, California to Greenville flights typically cost between $445 and $628 in January.The cheapest round-trip price found within the last 5 days was $349 on Delta (Jan 7-Jan 11).
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated September 18, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Entertainment
7.8
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Anderson
Seneca
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Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Santa Ana and Greenville flights
Browse other Santa Ana and Greenville flight options. Last updated on September 18, 2026.
Other flights from Santa Ana
Browse through other flights departing from Santa Ana. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Santa Ana to Greenville
Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$333 | Average$469 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$336 | Average$608 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$390 | Average$586 | FlexibilityNo cancel fee | On-time71% |