$174+ Cheap flights from Santa Ana, CA to Greenville (SNA - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/16. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
May 23 — May 301
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Greenville
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Best
Last-minute
One-way
Cheapest flights from Santa Ana to GreenvilleExplore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.
This Southwest deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:30 am
SNA
- GSP
2 stops10h 25m
Southwest
Wed 8/127:00 am
GSP
- SNA
2 stops9h 35m
Southwest
Deal found 4/22![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:25 pm
SNA
- GSP
1 stop8h 18m
Delta
Tue 6/211:00 am
GSP
- SNA
2 stops12h 34m
Delta
Deal found 4/21![Delta logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:55 am
SNA
- GSP
2 stops17h 38m
Multiple Airlines
Mon 6/18:28 pm
GSP
- SNA
1 stop18h 47m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/119:14 pm
SNA
- GSP
1 stop10h 30m
United Airlines
Wed 8/124:15 pm
GSP
- SNA
1 stop7h 25m
United Airlines
Deal found 4/22![United Airlines logo]()
$352
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:01 pm
SNA
- GSP
1 stop6h 56m
American Airlines
Mon 6/15:25 pm
GSP
- SNA
1 stop7h 36m
American Airlines
Deal found 4/22![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:45 am
SNA
- GSP
1 stop6h 27m
Delta
Sat 5/305:05 pm
GSP
- SNA
1 stop8h 24m
Delta
Deal found 4/22![Delta logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:41 pm
SNA
- GSP
1 stop28h 07m
Breeze Airways
Mon 6/18:28 pm
GSP
- SNA
1 stop18h 47m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$364
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:00 pm
SNA
- GSP
1 stop6h 43m
Delta
Tue 6/211:43 am
GSP
- SNA
2 stops13h 11m
Delta
Deal found 4/22![Delta logo]()
$367
Best flights from Santa Ana to GreenvilleDiscover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
Discover carefully curated flight deals from Santa Ana to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 23, 2026.
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:45 am
SNA
- GSP
1 stop9h 08m
Delta
Sat 6/68:45 am
GSP
- SNA
1 stop6h 55m
Delta
Deal found 4/21![Delta logo]()
$363
This United Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:26 pm
SNA
- GSP
2 stops12h 29m
United Airlines
Tue 6/24:15 pm
GSP
- SNA
1 stop7h 25m
United Airlines
Deal found 4/22![United Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:25 am
SNA
- GSP
2 stops9h 10m
Southwest
Mon 6/112:35 pm
GSP
- SNA
2 stops9h 40m
Southwest
Deal found 4/19![Southwest logo]()
$487
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:55 pm
SNA
- GSP
2 stops11h 09m
Delta
Tue 6/25:05 pm
GSP
- SNA
1 stop8h 24m
Delta
Deal found 4/22![Delta logo]()
$442
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:45 am
SNA
- GSP
2 stops8h 50m
Southwest
Mon 6/112:35 pm
GSP
- SNA
2 stops10h 00m
Southwest
Deal found 4/20![Southwest logo]()
$487
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:27 pm
SNA
- GSP
2 stops12h 31m
United Airlines
Tue 5/124:35 pm
GSP
- SNA
1 stop7h 09m
United Airlines
Deal found 4/23![United Airlines logo]()
$498
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:55 pm
SNA
- GSP
2 stops11h 12m
Delta
Tue 5/121:09 pm
GSP
- SNA
2 stops11h 45m
Delta
Deal found 4/23![Delta logo]()
$489
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:00 am
SNA
- GSP
2 stops11h 24m
Delta
Sun 5/241:09 pm
GSP
- SNA
2 stops11h 45m
Delta
Deal found 4/19![Delta logo]()
$508
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/115:05 pm
SNA
- GSP
2 stops12h 59m
Delta
Thu 5/145:40 am
GSP
- SNA
2 stops9h 15m
Delta
Deal found 4/22![Delta logo]()
$547
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:25 pm
SNA
- GSP
1 stop8h 18m
Delta
Sun 5/318:45 am
GSP
- SNA
1 stop6h 55m
Delta
Deal found 4/20![Delta logo]()
$551
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:00 am
SNA
- GSP
2 stops11h 24m
Delta
Sat 5/236:45 am
GSP
- SNA
1 stop8h 55m
Delta
Deal found 4/19![Delta logo]()
$583
Last-minute flights from Santa Ana to GreenvilleDiscover last-minute flight deals from Santa Ana to Greenville. Data last updated April 23, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Greenville. Data last updated April 23, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:45 am
SNA
- GSP
1 stop6h 27m
Delta
Sat 5/305:05 pm
GSP
- SNA
1 stop8h 24m
Delta
Deal found 4/22![Delta logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2710:55 am
SNA
- GSP
2 stops17h 38m
Multiple Airlines
Mon 6/18:28 pm
GSP
- SNA
1 stop18h 47m
Multiple Airlines
Deal found 4/22![Multiple Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:01 pm
SNA
- GSP
1 stop6h 56m
American Airlines
Mon 6/15:25 pm
GSP
- SNA
1 stop7h 36m
American Airlines
Deal found 4/22![American Airlines logo]()
$362
This Delta deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:25 pm
SNA
- GSP
1 stop8h 18m
Delta
Tue 6/211:00 am
GSP
- SNA
2 stops12h 34m
Delta
Deal found 4/21![Delta logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:41 pm
SNA
- GSP
1 stop28h 07m
Breeze Airways
Mon 6/18:28 pm
GSP
- SNA
1 stop18h 47m
Breeze Airways
Deal found 4/23![Breeze Airways logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:41 pm
SNA
- GSP
1 stop28h 07m
Multiple Airlines
Mon 6/18:28 pm
GSP
- SNA
2 stops22h 10m
Multiple Airlines
Deal found 4/21![Multiple Airlines logo]()
$371
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:00 pm
SNA
- GSP
1 stop6h 43m
Delta
Tue 6/211:43 am
GSP
- SNA
2 stops13h 11m
Delta
Deal found 4/22![Delta logo]()
$367
One-way flights from Santa Ana to GreenvilleSearch for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
Search for one-way flight options from Santa Ana to Greenville. Find affordable one-way fares based on user searches. Data last updated April 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:22 pm
SNA
- GSP
1 stop17h 04m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/192:24 pm
SNA
- GSP
3 stops38h 05m
Multiple Airlines
Deal found 4/20![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:10 pm
SNA
- GSP
3 stops42h 29m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:55 am
SNA
- GSP
2 stops41h 35m
Allegiant Air
Deal found 4/19![Allegiant Air logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:10 pm
SNA
- GSP
3 stops40h 33m
Multiple Airlines
Deal found 4/19![Multiple Airlines logo]()
$233
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:14 pm
SNA
- GSP
1 stop10h 23m
United Airlines
Deal found 4/20![United Airlines logo]()
$234
This Southwest deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:50 am
SNA
- GSP
2 stops9h 55m
Southwest
Deal found 4/20![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1911:44 am
SNA
- GSP
1 stop7h 04m
Delta
Deal found 4/19![Delta logo]()
$242
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:45 am
SNA
- GSP
2 stops13h 49m
United Airlines
Deal found 4/23![United Airlines logo]()
$330
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2212:25 pm
SNA
- GSP
1 stop8h 18m
Delta
Deal found 4/22![Delta logo]()
$370
Find flight deals from Santa Ana to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $310 (Southwest) |
One-way from | $174 (Kiwi.com) |
Popular in | April |
Cheapest in | July |
Average price | $946 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Sat 5/30
6:45 am-6:53 pm
1 stop9h 08m
Greenville
Sat 6/6
8:45 am-12:40 pm
1 stop6h 55m
$363
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 5/27
6:55 pm-9:04 am
2 stops11h 09m
Greenville
Tue 6/2
5:05 pm-10:29 pm
1 stop8h 24m
$442
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
6:26 pm-9:55 am
2 stops12h 29m
Greenville
Tue 6/2
4:15 pm-8:40 pm
1 stop7h 25m
$478
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
10:25 am-10:35 pm
2 stops9h 10m
Greenville
Mon 6/1
12:35 pm-7:15 pm
2 stops9h 40m
$487
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Fri 5/29
10:45 am-10:35 pm
2 stops8h 50m
Greenville
Mon 6/1
12:35 pm-7:35 pm
2 stops10h 00m
$487
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Fri 5/8
6:55 pm-9:07 am
2 stops11h 12m
Greenville
Tue 5/12
1:09 pm-9:54 pm
2 stops11h 45m
$489
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Fri 5/8
6:27 pm-9:58 am
2 stops12h 31m
Greenville
Tue 5/12
4:35 pm-8:44 pm
1 stop7h 09m
$498
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Wed 5/20
8:00 am-10:24 pm
2 stops11h 24m
Greenville
Sun 5/24
1:09 pm-9:54 pm
2 stops11h 45m
$508
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Mon 5/11
5:05 pm-9:04 am
2 stops12h 59m
Greenville
Thu 5/14
5:40 am-11:55 am
2 stops9h 15m
$547
Quickest round-trip
Santa AnaGreenville
SNA - GSP
SNAGSP
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
12:25 pm-11:43 pm
1 stop8h 18m
Greenville
Sun 5/31
8:45 am-12:40 pm
1 stop6h 55m
$551
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Greenville in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana, California-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana, California-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana, California-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
SNA-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Greenville
What is the cheapest month to book a flight from Santa Ana, California to Greenville?
Currently, July is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $377). Flying from Santa Ana, California to Greenville in April is currently the most expensive (average of $946). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santa Ana, California to Greenville?
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated April 23, 2026.
See what other customers who have flown with Delta,United Airlines, andAmerican Airlines from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Entertainment
7.8
Overall
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Anderson
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Alternative routes for Santa Ana to Greenville
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 23, 2026.
Santa Ana and Greenville flights
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Other flights from Santa Ana
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Top 3 airlines flying from Santa Ana to Greenville
Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$324 | Average$457 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$337 | Average$462 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$389 | Average$626 | FlexibilityNo cancel fee | On-time69% |