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$199+ Cheap flights from Santa Ana, CA to Greenville (SNA - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — GSP
Feb 13 — Feb 201
Fri 2/13
Fri 2/20
1 adult, Economy
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Cheap flight deals from Santa Ana to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 14, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$391
(Southwest)

One-way from

$199
(American Airlines)

Popular in

December

Cheapest in

July

Average price

$491
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Greenville flight deals.
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Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Greenville flights.
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From Santa Ana J. Wayne/Orange Cnty to Greenville
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One-way flight from Santa Ana J. Wayne/Orange Cnty to Greenville
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Highest demand for flights based on searches. 9% potential increase in price ($53 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Santa Ana to Greenville

Cheapest flights from Santa Ana to Greenville
Explore the most affordable flight options available from Santa Ana to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 14, 2026.

This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:45 pm
SNA
-
GSP
2 stops11h 55m
Southwest
Wed 2/1111:15 am
GSP
-
SNA
2 stops11h 20m
Southwest
Deal found 1/14$391
This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/99:10 pm
SNA
-
GSP
1 stop10h 58m
United Airlines
Wed 2/115:34 pm
GSP
-
SNA
1 stop7h 50m
United Airlines
Deal found 1/14$404
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:10 am
SNA
-
GSP
2 stops9h 35m
Southwest
Fri 3/138:00 am
GSP
-
SNA
2 stops11h 40m
Southwest
Deal found 1/14$441
This Southwest deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/86:40 pm
SNA
-
GSP
2 stops12h 30m
Southwest
Wed 2/1111:15 am
GSP
-
SNA
2 stops11h 20m
Southwest
Deal found 1/14$454
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/811:42 am
SNA
-
GSP
1 stop9h 17m
American Airlines
Wed 2/114:40 pm
GSP
-
SNA
1 stop9h 16m
American Airlines
Deal found 1/14$474
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/146:35 pm
SNA
-
GSP
2 stops12h 26m
United Airlines
Wed 2/186:30 am
GSP
-
SNA
1 stop8h 18m
United Airlines
Deal found 1/12$482
This Delta deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/219:20 pm
SNA
-
GSP
1 stop9h 07m
Delta
Thu 6/256:45 am
GSP
-
SNA
1 stop7h 10m
Delta
Deal found 1/13$523

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
Use the filters below to find and compare flights from Santa Ana to Greenville that are best for you.

Fly from

Santa Ana

Fly to

Greenville

Route

Depart

Return

Price

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

7:45 pm-10:40 am

2 stops11h 55m

Greenville

Wed 2/11

11:15 am-7:35 pm

2 stops11h 20m

$391

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Mon 2/9

9:10 pm-11:08 am

1 stop10h 58m

Greenville

Wed 2/11

5:34 pm-10:24 pm

1 stop7h 50m

$404

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sun 2/8

6:40 pm-10:10 am

2 stops12h 30m

Greenville

Wed 2/11

11:15 am-7:35 pm

2 stops11h 20m

$454

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sun 2/8

11:42 am-11:59 pm

1 stop9h 17m

Greenville

Wed 2/11

4:40 pm-10:56 pm

1 stop9h 16m

$474

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

6:35 pm-10:01 am

2 stops12h 26m

Greenville

Wed 2/18

6:30 am-11:48 am

1 stop8h 18m

$482

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sun 6/21

9:20 pm-9:27 am

1 stop9h 07m

Greenville

Thu 6/25

6:45 am-10:55 am

1 stop7h 10m

$523

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

10:53 am-8:56 pm

1 stop7h 03m

Greenville

Fri 2/6

7:50 am-1:04 pm

1 stop8h 14m

$543

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

7:45 am-5:55 pm

1 stop7h 10m

$199

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Fri 1/30

7:41 pm-8:58 am

3 stops58h 17m

$206

Santa AnaGreenville

SNA - GSP

SNAGSP

Santa Ana J. Wayne/Orange Cnty

Sun 5/3

9:45 pm-9:02 am

1 stop8h 17m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/13

Showing 1-10 of 16 results
1
2

Compare providers for flights from Santa Ana to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Greenville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Greenville

What is the cheapest month to book a flight from Santa Ana, California to Greenville?

Currently, May is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $115). Flying from Santa Ana, California to Greenville in January is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated January 14, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Santa Ana to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Delta
7.9
Good
8,040 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
United Airlines
7.4
Good
9,156 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
American Airlines
7.2
Good
11,119 reviews
Delta
7.9
Good
8,040 reviews

Entertainment

7.8

Food

7.2

Overall

7.9

Boarding

8.1

Comfort

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Greenville?

    A quick flight from Santa Ana, California to Greenville can take about 9h 17m. Southwest provides one of the quickest options available for as low as $474. The distance from Santa Ana, California to Greenville is about 2025 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Santa Ana, California to Greenville round-trip?

    According to our current data, American Airlines ($324), Delta ($337), and United Airlines ($434) offers the cheapest pricing from Santa Ana, California to Greenville. American Airlines is priced at 35% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Santa Ana to Greenville that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Greenville.

  • Can I find deals for business class flights from Santa Ana to Greenville?

    Yes. Cheapflights offers flight deals from Santa Ana to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Greenville?

    Currently, May is the cheapest month in which you can book a flight from Santa Ana, California to Greenville (average of $115). Flying from Santa Ana, California to Greenville in January is currently the most expensive (average of $246). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 3 airlines flying from Santa Ana to Greenville

Discover the top 3 airlines that operate flights from Santa Ana to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$324Average$456FlexibilityNo cancel feeOn-time71%
DeltaCheapest$337Average$459FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$434Average$559FlexibilityNo cancel feeOn-time69%

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