$202+ Cheap flights from San Francisco to Greenville (SFO - GSP)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/19. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Jun 22 — Jun 291
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to Greenville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to Greenville
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Best
Last-minute
One-way
Cheapest flights from San Francisco to GreenvilleExplore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2026.
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2026.
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
SFO
- GSP
1 stop8h 17m
American Airlines
Tue 8/256:47 am
GSP
- SFO
1 stop9h 26m
American Airlines
Deal found 5/22![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:30 pm
SFO
- GSP
1 stop8h 45m
Southwest
Sat 8/811:05 am
GSP
- SFO
1 stop7h 45m
Southwest
Deal found 5/22![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:25 am
SFO
- GSP
2 stops8h 35m
Southwest
Wed 7/297:00 am
GSP
- SFO
2 stops11h 00m
Southwest
Deal found 5/20![Southwest logo]()
$405
This Delta deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:10 pm
SFO
- GSP
1 stop9h 30m
Delta
Tue 8/255:20 pm
GSP
- SFO
1 stop9h 34m
Delta
Deal found 5/18![Delta logo]()
$408
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:15 pm
SFO
- GSP
1 stop7h 12m
American Airlines
Tue 8/256:47 am
GSP
- SFO
2 stops9h 25m
American Airlines
Deal found 5/20![American Airlines logo]()
$413
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:00 am
SFO
- GSP
1 stop7h 42m
American Airlines
Wed 7/228:01 pm
GSP
- SFO
1 stop7h 42m
American Airlines
Deal found 5/21![American Airlines logo]()
$431
Best flights from San Francisco to GreenvilleDiscover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 23, 2026.
Discover carefully curated flight deals from San Francisco to Greenville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 23, 2026.
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:00 am
SFO
- GSP
2 stops10h 05m
Southwest
Sun 11/158:15 am
GSP
- SFO
1 stop8h 30m
Southwest
Deal found 5/18![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2211:59 pm
SFO
- GSP
1 stop7h 48m
Delta
Sun 7/267:44 pm
GSP
- SFO
1 stop7h 52m
Delta
Deal found 5/20![Delta logo]()
$487
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1710:50 pm
SFO
- GSP
1 stop10h 25m
Southwest
Wed 7/2212:50 pm
GSP
- SFO
2 stops12h 25m
Southwest
Deal found 5/19![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:25 pm
SFO
- GSP
1 stop10h 25m
Southwest
Fri 11/276:40 am
GSP
- SFO
2 stops10h 45m
Southwest
Deal found 5/23![Southwest logo]()
$472
This Delta deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:59 pm
SFO
- GSP
1 stop9h 00m
Delta
Thu 6/257:51 pm
GSP
- SFO
1 stop7h 54m
Delta
Deal found 5/20![Delta logo]()
$523
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:20 am
SFO
- GSP
2 stops11h 40m
Southwest
Thu 6/187:05 am
GSP
- SFO
2 stops10h 20m
Southwest
Deal found 5/18![Southwest logo]()
$513
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2010:50 pm
SFO
- GSP
1 stop10h 20m
Southwest
Sat 6/271:55 pm
GSP
- SFO
2 stops12h 35m
Southwest
Deal found 5/23![Southwest logo]()
$514
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/199:10 pm
SFO
- GSP
1 stop13h 10m
Southwest
Fri 6/2612:55 pm
GSP
- SFO
1 stop10h 00m
Southwest
Deal found 5/21![Southwest logo]()
$514
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/135:20 am
SFO
- GSP
2 stops11h 40m
Southwest
Sat 6/201:55 pm
GSP
- SFO
1 stop9h 25m
Southwest
Deal found 5/21![Southwest logo]()
$532
Last-minute flights from San Francisco to GreenvilleDiscover last-minute flight deals from San Francisco to Greenville. Data last updated May 23, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to Greenville. Data last updated May 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:00 am
SFO
- GSP
1 stop7h 41m
American Airlines
Thu 5/287:54 pm
GSP
- SFO
1 stop7h 54m
American Airlines
Deal found 5/21![American Airlines logo]()
$467
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:01 pm
SFO
- GSP
1 stop8h 58m
American Airlines
Wed 6/245:25 pm
GSP
- SFO
1 stop10h 23m
American Airlines
Deal found 5/21![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:50 am
SFO
- GSP
2 stops10h 10m
Southwest
Wed 6/248:25 am
GSP
- SFO
1 stop14h 25m
Southwest
Deal found 5/21![Southwest logo]()
$448
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/205:20 am
SFO
- GSP
2 stops11h 40m
Southwest
Sat 6/271:55 pm
GSP
- SFO
2 stops12h 35m
Southwest
Deal found 5/23![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:50 pm
SFO
- GSP
1 stop10h 25m
Southwest
Fri 6/268:30 am
GSP
- SFO
1 stop12h 00m
Southwest
Deal found 5/23![Southwest logo]()
$478
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2211:49 pm
SFO
- GSP
1 stop7h 19m
American Airlines
Thu 6/255:25 pm
GSP
- SFO
1 stop10h 23m
American Airlines
Deal found 5/23![American Airlines logo]()
$482
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:40 pm
SFO
- GSP
2 stops10h 25m
Southwest
Sat 7/48:05 am
GSP
- SFO
1 stop9h 25m
Southwest
Deal found 5/22![Southwest logo]()
$492
One-way flights from San Francisco to GreenvilleSearch for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated May 23, 2026.
Search for one-way flight options from San Francisco to Greenville. Find affordable one-way fares based on user searches. Data last updated May 23, 2026.
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:30 pm
SFO
- GSP
1 stop9h 28m
Delta
Deal found 5/22![Delta logo]()
$202
This Southwest deal was found by Cheapflights users on 5/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/169:10 pm
SFO
- GSP
1 stop13h 00m
Southwest
Deal found 5/18![Southwest logo]()
$203
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:58 pm
SFO
- GSP
1 stop8h 57m
American Airlines
Deal found 5/19![American Airlines logo]()
$211
This Southwest deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 am
SFO
- GSP
2 stops10h 05m
Southwest
Deal found 5/19![Southwest logo]()
$216
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/279:56 pm
SFO
- GSP
1 stop8h 17m
Delta
Deal found 5/22![Delta logo]()
$234
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:25 am
SFO
- GSP
2 stops8h 35m
Southwest
Deal found 5/22![Southwest logo]()
$239
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:50 am
SFO
- GSP
1 stop9h 30m
Delta
Deal found 5/22![Delta logo]()
$240
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:01 pm
SFO
- GSP
1 stop8h 58m
American Airlines
Deal found 5/22![American Airlines logo]()
$243
This Southwest deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1710:25 am
SFO
- GSP
2 stops8h 35m
Southwest
Deal found 5/22![Southwest logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:52 pm
SFO
- GSP
2 stops23h 06m
Multiple Airlines
Deal found 5/21![Multiple Airlines logo]()
$253
This Delta deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3111:59 pm
SFO
- GSP
1 stop9h 15m
Delta
Deal found 5/22![Delta logo]()
$260
Find flight deals from San Francisco to Greenville
Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $383 (American Airlines) |
One-way from | $202 (Delta) |
Popular in | May |
Cheapest in | January |
Average price | $640 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2026.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 11/11
5:00 am-6:05 pm
2 stops10h 05m
Greenville
Sun 11/15
8:15 am-1:45 pm
1 stop8h 30m
$436
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Fri 7/17
10:50 pm-12:15 pm
1 stop10h 25m
Greenville
Wed 7/22
12:50 pm-10:15 pm
2 stops12h 25m
$447
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 11/18
9:25 pm-10:50 am
1 stop10h 25m
Greenville
Fri 11/27
6:40 am-2:25 pm
2 stops10h 45m
$472
Quickest round-trip
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 7/22
11:59 pm-10:47 am
1 stop7h 48m
Greenville
Sun 7/26
7:44 pm-12:36 am
1 stop7h 52m
$487
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 6/13
5:20 am-8:00 pm
2 stops11h 40m
Greenville
Thu 6/18
7:05 am-2:25 pm
2 stops10h 20m
$513
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 6/20
10:50 pm-12:10 pm
1 stop10h 20m
Greenville
Sat 6/27
1:55 pm-11:30 pm
2 stops12h 35m
$514
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Fri 6/19
9:10 pm-1:20 pm
1 stop13h 10m
Greenville
Fri 6/26
12:55 pm-7:55 pm
1 stop10h 00m
$514
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Mon 6/22
10:59 pm-10:59 am
1 stop9h 00m
Greenville
Thu 6/25
7:51 pm-12:45 am
1 stop7h 54m
$523
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Sat 6/13
5:20 am-8:00 pm
2 stops11h 40m
Greenville
Sat 6/20
1:55 pm-8:20 pm
1 stop9h 25m
$532
Cheapest one-way
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Tue 6/16
9:10 pm-1:10 pm
1 stop13h 00m
$203
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from San Francisco to Greenville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Francisco to Greenville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Francisco-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Francisco-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Francisco-Greenville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Francisco-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Francisco-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Francisco to Greenville
Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
SFO-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to Greenville
How far ahead should I book a flight from San Francisco to Greenville?
To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 29 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Francisco to Greenville?
Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $305). Flying from San Francisco to Greenville in May is currently the most expensive (average of $640). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to Greenville?
Reviews of airlines servicing Greenville
Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated May 23, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Crew
8.6
Overall
7.9
Boarding
8.1
Food
7.0
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Greenville?
Book flights to Greenville if you plan to visit one of these locationsGreer
Simpsonville
Greenwood
Duncan
Seneca
Browse thousands of different options on Cheapflights for your next trip
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Other flights to Greenville
Explore flights to Greenville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 23, 2026.
San Francisco and Greenville flights
Browse other San Francisco and Greenville flight options. Last updated on May 23, 2026.
Other flights from San Francisco
Browse through other flights departing from San Francisco. Flights are based on user searches made on Cheapflights and were last updated on May 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from San Francisco to Greenville
Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$463 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$305 | Average$566 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$313 | Average$434 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$424 | Average$576 | FlexibilityNo cancel fee | On-time69% |