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$176+ Cheap flights from San Francisco to Greenville (SFO - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — GSP
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheapflights Tip: The best prices from San Francisco to Greenville are usually found in September or August, booked 15 days in advance, depart on a Saturday or Wednesday and return on a Wednesday

Cheap flight deals from San Francisco to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from San Francisco (SFO) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 30, 2025.

Round-trip from

$351
(Southwest)

One-way from

$176
(American Airlines)

Popular in

December

Cheapest in

September

Average price

$462
From San Francisco to Greenville
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One-way flight from San Francisco to Greenville
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Highest demand for flights based on searches. 14% potential increase in price ($80 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from San Francisco to Greenville

Cheapest flights from San Francisco to Greenville
Explore the most affordable flight options available from San Francisco to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This Southwest deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/159:05 pmSFO - GSP
1 stop9h 45mSouthwest
Thu 9/2510:45 amGSP - SFO
1 stop8h 55mSouthwest
Deal found 6/28$351
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/2411:15 pmSFO - GSP
1 stop7h 34mUnited Airlines
Mon 8/254:30 pmGSP - SFO
1 stop9h 40mUnited Airlines
Deal found 6/29$373
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/95:50 amSFO - GSP
1 stop9h 19mDelta
Sun 8/175:30 amGSP - SFO
1 stop7h 40mDelta
Deal found 6/29$381
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/410:00 amSFO - GSP
1 stop7h 25mAmerican Airlines
Mon 9/86:33 pmGSP - SFO
1 stop7h 42mAmerican Airlines
Deal found 6/28$389

Cheapflights Fare Finder

Customize your flight search to find flights from San Francisco to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from San Francisco to Greenville that are best for you.

Fly from

San Francisco

Fly to

Greenville

Route

Depart

Return

Price

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 9/15

10:45 pm-10:31 am

1 stop8h 46m

Greenville

Thu 9/25

3:42 pm-9:02 pm

1 stop8h 20m

$351

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Wed 10/15

9:05 pm-9:55 am

1 stop9h 50m

Greenville

Sat 10/25

10:30 am-5:35 pm

1 stop10h 05m

$354

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sun 8/24

11:15 pm-9:49 am

1 stop7h 34m

Greenville

Mon 8/25

4:30 pm-11:10 pm

1 stop9h 40m

$373

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Thu 9/4

10:00 am-8:25 pm

1 stop7h 25m

Greenville

Mon 9/8

6:33 pm-11:15 pm

1 stop7h 42m

$389

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 9/15

8:00 am-7:13 pm

1 stop8h 13m

$176

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Sun 8/3

9:35 pm-9:01 am

1 stop8h 26m

$240

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Fri 7/25

5:30 am-5:05 pm

2 stops8h 35m

$249

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 9/15

10:53 pm-9:01 pm

2 stops19h 08m

$288

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Mon 7/7

11:59 pm-2:54 pm

2 stops11h 55m

$381

San FranciscoGreenville

SFO - GSP

SFOGSP

San Francisco

Fri 7/25

12:29 pm-9:54 am

3 stops42h 25m

$524

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from San Francisco to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from San Francisco with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco to Greenville

How far ahead should I book a flight from San Francisco to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from San Francisco to Greenville. Price data was last updated on June 27, 2025.

To ensure you get the cheapest price possible for a flight from San Francisco to Greenville, you should look to book at least 15 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from San Francisco to Greenville?

Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $329). Flying from San Francisco to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SFO to GSP?

Find hourly flight availability from San Francisco to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

A simple way to save on the total cost of your ticket is to fly from San Francisco to Greenville in the morning. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated June 30, 2025.
See what other customers who have flown with Breeze Airways, Southwest, and Delta from San Francisco to Greenville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Breeze Airways
8.1
Very good
182 reviews
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Southwest
8.0
Very good
4,278 reviews
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
Delta
8.0
Very good
7,973 reviews
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
United Airlines
7.4
Good
8,852 reviews
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!
American Airlines
7.2
Good
10,000 reviews
Breeze Airways
8.1
Very good
182 reviews

Food

6.8

Overall

8.1

Comfort

8.2

Entertainment

6.6

Crew

8.8

Boarding

8.4

Reviews

1 / 11
10.0
Excellent

Dena,Dec 2024

LAS - BDL

It was comfortable and the crew was great! A few free snacks offered would be nice!

Related info for your journey

Find useful and relevant information for your journey from San Francisco to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Francisco to Greenville round-trip?

    Cheapflights users have booked flights from San Francisco to Greenville round-trip from $351. Other airlines that can offer you cheap pricing are United Airlines, from $373, and Delta, from $381. Southwest is currently priced 25% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Francisco to Greenville one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $176. Delta flights start at $240 while deals on Southwest start at $249 one-way.

  • Can I find deals for flights from San Francisco to Greenville that include hotel bookings?

    Yes. In addition to deals on San Francisco to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco to Greenville.

  • Can I find deals for business class flights from San Francisco to Greenville?

    Yes. Cheapflights offers flight deals from San Francisco to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco to Greenville?

    Currently, January is the cheapest month in which you can book a flight from San Francisco to Greenville (average of $329). Flying from San Francisco to Greenville in March is currently the most expensive (average of $385). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
Simpsonville
Duncan
Seneca
Anderson

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Top 4 airlines flying from San Francisco to Greenville

Discover the top 4 airlines that operate flights from San Francisco to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$259Average$429FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$434FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$317Average$456FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$446Average$574FlexibilityNo cancel feeOn-time69%

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