$115+ Cheap flights from San Francisco (SFO) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CHS
Jun 11 — Jun 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Francisco to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to South Carolina
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Francisco to South CarolinaExplore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
Explore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 12, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/512:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Fri 9/116:10 am
CHS
- SFO
1 stop7h 59m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/1411:54 am
SFO
- CHS
1 stop6h 40m
Breeze Airways
Fri 9/186:10 am
CHS
- SFO
1 stop7h 59m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:36 pm
SFO
- CHS
1 stop7h 19m
Breeze Airways
Sat 10/246:20 am
CHS
- SFO
1 stop8h 31m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/712:36 pm
SFO
- CHS
1 stop7h 19m
Breeze Airways
Tue 11/107:00 am
CHS
- SFO
1 stop8h 01m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$293
This Mytrip deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Wed 6/36:30 am
CHS
- SFO
1 stop8h 07m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$297
This Frontier deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:33 pm
SFO
- CLT
1 stop11h 58m
Frontier
Sat 6/612:08 pm
CLT
- SFO
1 stop13h 56m
Frontier
Deal found 5/8![Frontier logo]()
$300
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/185:20 am
SFO
- CAE
1 stop8h 25m
United Airlines
Wed 11/257:35 pm
CAE
- SFO
1 stop8h 41m
United Airlines
Deal found 5/7![United Airlines logo]()
$301
This Super.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:43 pm
SFO
- CLT
1 stop20h 42m
Frontier
Mon 6/1510:14 pm
CLT
- SFO
1 stop16h 29m
Frontier
Deal found 5/10![Frontier logo]()
$302
This Breeze Airways deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:46 pm
SFO
- CHS
1 stop6h 50m
Breeze Airways
Tue 10/137:00 am
CHS
- SFO
1 stop8h 01m
Breeze Airways
Deal found 5/12![Breeze Airways logo]()
$304
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:52 pm
SFO
- CLT
1 stop26h 27m
Frontier
Wed 6/1010:14 pm
CLT
- SFO
1 stop16h 29m
Frontier
Deal found 5/7![Frontier logo]()
$304
This Trip.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/112:38 pm
SFO
- CLT
1 stop26h 41m
Frontier
Wed 7/810:14 pm
CLT
- SFO
1 stop29h 04m
Frontier
Deal found 5/9![Frontier logo]()
$307
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:18 pm
SFO
- CHS
1 stop6h 48m
Multiple Airlines
Wed 8/195:26 pm
CHS
- SFO
2 stops18h 20m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$311
Best flights from San Francisco to South CarolinaDiscover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
Discover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 12, 2026.
This Breeze Airways deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:46 pm
SFO
- CHS
1 stop6h 50m
Breeze Airways
Tue 10/137:00 am
CHS
- SFO
1 stop8h 01m
Breeze Airways
Deal found 5/10![Breeze Airways logo]()
$310
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/69:15 pm
SFO
- CHS
1 stop8h 36m
United Airlines
Sat 6/137:47 pm
CHS
- SFO
1 stop8h 28m
United Airlines
Deal found 5/9![United Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:30 pm
SFO
- CHS
1 stop9h 12m
Delta
Sat 10/2412:15 pm
CHS
- SFO
1 stop7h 56m
Delta
Deal found 5/11![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:00 am
SFO
- CHS
2 stops11h 25m
Southwest
Wed 7/84:50 pm
CHS
- SFO
1 stop8h 35m
Southwest
Deal found 5/7![Southwest logo]()
$362
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/65:23 am
SFO
- FLO
2 stops13h 37m
American Airlines
Sat 6/132:35 pm
FLO
- SFO
1 stop8h 21m
American Airlines
Deal found 5/7![American Airlines logo]()
$462
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 am
SFO
- CHS
1 stop9h 16m
Delta
Sun 7/267:59 pm
CHS
- SFO
1 stop7h 37m
Delta
Deal found 5/9![Delta logo]()
$323
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/511:05 pm
SFO
- CAE
1 stop7h 51m
United Airlines
Mon 6/157:45 pm
CAE
- SFO
1 stop8h 30m
United Airlines
Deal found 5/9![United Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:20 am
SFO
- CHS
2 stops11h 10m
Southwest
Sat 10/2410:55 am
CHS
- SFO
1 stop8h 55m
Southwest
Deal found 5/11![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/175:40 am
SFO
- CHS
1 stop9h 16m
Delta
Sun 7/197:59 pm
CHS
- SFO
1 stop7h 37m
Delta
Deal found 5/8![Delta logo]()
$333
This Breeze Airways deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:36 pm
SFO
- CHS
1 stop7h 19m
Breeze Airways
Sun 10/117:00 am
CHS
- SFO
1 stop8h 01m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$389
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/68:15 pm
SFO
- CHS
2 stops12h 10m
Southwest
Sat 9/121:20 pm
CHS
- SFO
2 stops10h 15m
Southwest
Deal found 5/8![Southwest logo]()
$371
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1110:45 pm
SFO
- CAE
1 stop7h 37m
Delta
Wed 7/151:47 pm
CAE
- SFO
1 stop9h 18m
Delta
Deal found 5/11![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:59 am
SFO
- HHH
2 stops12h 35m
American Airlines
Thu 5/285:21 pm
HHH
- SFO
1 stop8h 28m
American Airlines
Deal found 5/6![American Airlines logo]()
$464
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1910:50 pm
SFO
- CHS
1 stop10h 45m
Southwest
Mon 6/221:55 pm
CHS
- SFO
1 stop9h 00m
Southwest
Deal found 5/7![Southwest logo]()
$404
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/910:38 pm
SFO
- SAV
1 stop8h 45m
United Airlines
Sun 8/167:05 am
SAV
- SFO
1 stop8h 09m
United Airlines
Deal found 5/9![United Airlines logo]()
$487
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:30 am
SFO
- MYR
1 stop10h 05m
Southwest
Wed 7/87:00 am
MYR
- SFO
1 stop9h 40m
Southwest
Deal found 5/7![Southwest logo]()
$408
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:00 pm
SFO
- MYR
1 stop9h 47m
Delta
Thu 8/1311:43 am
MYR
- SFO
1 stop8h 41m
Delta
Deal found 5/10![Delta logo]()
$415
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/235:23 am
SFO
- AGS
1 stop7h 07m
American Airlines
Sat 7/47:00 am
AGS
- SFO
1 stop9h 06m
American Airlines
Deal found 5/8![American Airlines logo]()
$521
This Southwest deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:55 am
SFO
- CLT
2 stops9h 05m
Southwest
Sat 10/248:25 am
CLT
- SFO
1 stop7h 45m
Southwest
Deal found 5/11![Southwest logo]()
$413
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2011:30 pm
SFO
- MYR
1 stop8h 06m
United Airlines
Sat 6/2711:31 am
MYR
- SFO
1 stop10h 53m
United Airlines
Deal found 5/9![United Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:07 am
SFO
- AGS
2 stops10h 23m
American Airlines
Sat 5/3012:43 pm
AGS
- SFO
1 stop10h 13m
American Airlines
Deal found 5/8![American Airlines logo]()
$526
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/176:00 am
SFO
- CLT
1 stop9h 02m
Delta
Sat 6/206:20 am
CLT
- SFO
1 stop8h 15m
Delta
Deal found 5/8![Delta logo]()
$451
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:20 am
SFO
- CLT
2 stops11h 05m
Southwest
Sat 10/174:35 pm
CLT
- SFO
1 stop8h 25m
Southwest
Deal found 5/9![Southwest logo]()
$413
This United Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:35 pm
SFO
- CAE
1 stop8h 10m
United Airlines
Sun 5/246:33 am
CAE
- SFO
1 stop9h 42m
United Airlines
Deal found 5/8![United Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2311:25 am
SFO
- AGS
1 stop9h 05m
American Airlines
Wed 5/276:30 am
AGS
- SFO
1 stop9h 43m
American Airlines
Deal found 5/8![American Airlines logo]()
$554
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:00 am
SFO
- SAV
1 stop7h 42m
Delta
Mon 8/105:18 pm
SAV
- SFO
1 stop9h 29m
Delta
Deal found 5/11![Delta logo]()
$459
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:55 am
SFO
- CLT
2 stops9h 05m
Southwest
Sun 10/116:00 am
CLT
- SFO
2 stops10h 40m
Southwest
Deal found 5/8![Southwest logo]()
$446
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/235:40 am
SFO
- SAV
1 stop8h 50m
Delta
Mon 7/277:07 pm
SAV
- SFO
1 stop8h 29m
Delta
Deal found 5/11![Delta logo]()
$459
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:30 pm
SFO
- CAE
1 stop9h 26m
United Airlines
Mon 6/157:45 pm
CAE
- SFO
1 stop8h 30m
United Airlines
Deal found 5/10![United Airlines logo]()
$563
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:29 am
SFO
- MYR
1 stop7h 09m
American Airlines
Sun 7/124:42 pm
MYR
- SFO
1 stop9h 36m
American Airlines
Deal found 5/11![American Airlines logo]()
$583
Last-minute flights from San Francisco to South CarolinaDiscover last-minute flight deals from San Francisco to South Carolina. Data last updated May 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to South Carolina. Data last updated May 12, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1811:59 pm
SFO
- CLT
1 stop10h 40m
Frontier
Thu 5/212:10 pm
CLT
- SFO
1 stop8h 39m
Frontier
Deal found 5/7![Frontier logo]()
$320
This Mytrip deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Wed 6/36:30 am
CHS
- SFO
1 stop8h 07m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$297
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Sat 5/306:30 am
CHS
- SFO
1 stop8h 07m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$317
This Frontier deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:33 pm
SFO
- CLT
1 stop11h 58m
Frontier
Sat 6/612:08 pm
CLT
- SFO
1 stop13h 56m
Frontier
Deal found 5/8![Frontier logo]()
$300
This CheapOair deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Tue 6/27:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$325
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Mon 6/17:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$321
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:23 am
SFO
- CHS
1 stop10h 06m
American Airlines
Fri 6/53:12 pm
CHS
- SFO
1 stop9h 07m
American Airlines
Deal found 5/11![American Airlines logo]()
$323
This Booking.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:52 pm
SFO
- CLT
1 stop26h 27m
Frontier
Wed 6/1010:14 pm
CLT
- SFO
1 stop16h 29m
Frontier
Deal found 5/7![Frontier logo]()
$304
This Super.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:43 pm
SFO
- CLT
1 stop20h 42m
Frontier
Mon 6/1510:14 pm
CLT
- SFO
1 stop16h 29m
Frontier
Deal found 5/10![Frontier logo]()
$302
This Super.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2412:38 pm
SFO
- CLT
1 stop26h 41m
Frontier
Wed 7/1510:14 pm
CLT
- SFO
1 stop29h 04m
Frontier
Deal found 5/11![Frontier logo]()
$323
This Expedia deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/269:43 pm
SFO
- CLT
1 stop20h 42m
Frontier
Wed 7/110:14 pm
CLT
- SFO
1 stop29h 13m
Frontier
Deal found 5/8![Frontier logo]()
$314
This Delta deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2711:59 pm
SFO
- CHS
1 stop7h 01m
Delta
Tue 6/306:15 am
CHS
- SFO
1 stop7h 12m
Delta
Deal found 5/8![Delta logo]()
$328
One-way flights from San Francisco to South CarolinaSearch for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
Search for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated May 12, 2026.
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$115
This Breeze Airways deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:36 pm
SFO
- CHS
1 stop7h 19m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$128
This Breeze Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Deal found 5/7![Breeze Airways logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$135
This CheapOair deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:44 pm
SFO
- CLT
1 stop7h 15m
Frontier
Deal found 5/11![Frontier logo]()
$135
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$139
This Super.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:00 am
SFO
- CLT
1 stop9h 19m
Frontier
Deal found 5/11![Frontier logo]()
$139
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Deal found 5/11![Breeze Airways logo]()
$140
This Priceline deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/283:33 pm
SFO
- CLT
1 stop11h 58m
Frontier
Deal found 5/8![Frontier logo]()
$141
This Super.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/129:43 pm
SFO
- CLT
1 stop20h 42m
Frontier
Deal found 5/11![Frontier logo]()
$144
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
SFO
- CLT
1 stop9h 18m
Frontier
Deal found 5/10![Frontier logo]()
$145
Find flight deals from San Francisco to South Carolina
Keep the following information in mind while searching for San Francisco to South Carolina flight deals. Data was last updated May 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $297 (Mytrip) |
One-way from | $115 (Booking.com) |
Popular in | March |
Cheapest in | February |
Average price | $521 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Tue 10/6
12:46 pm-10:36 pm
1 stop6h 50m
Charleston
Tue 10/13
7:00 am-12:01 pm
1 stop8h 01m
$310
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Sat 6/6
9:15 pm-8:51 am
1 stop8h 36m
Charleston
Sat 6/13
7:47 pm-1:15 am
1 stop8h 28m
$323
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Wed 10/21
9:30 pm-9:42 am
1 stop9h 12m
Charleston
Sat 10/24
12:15 pm-5:11 pm
1 stop7h 56m
$323
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Fri 7/17
5:40 am-5:56 pm
1 stop9h 16m
Charleston
Sun 7/26
7:59 pm-12:36 am
1 stop7h 37m
$323
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Fri 7/17
5:40 am-5:56 pm
1 stop9h 16m
Charleston
Sun 7/19
7:59 pm-12:36 am
1 stop7h 37m
$333
San FranciscoColumbia
SFO - CAE
SFOCAE
San Francisco
Fri 6/5
11:05 pm-9:56 am
1 stop7h 51m
Columbia Metropolitan
Mon 6/15
7:45 pm-1:15 am
1 stop8h 30m
$357
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Wed 7/1
6:00 am-8:25 pm
2 stops11h 25m
Charleston
Wed 7/8
4:50 pm-10:25 pm
1 stop8h 35m
$362
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Wed 10/21
6:20 am-8:30 pm
2 stops11h 10m
Charleston
Sat 10/24
10:55 am-4:50 pm
1 stop8h 55m
$362
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Sun 9/6
8:15 pm-11:25 am
2 stops12h 10m
Charleston
Sat 9/12
1:20 pm-8:35 pm
2 stops10h 15m
$371
San FranciscoColumbia
SFO - CAE
SFOCAE
San Francisco
Sat 7/11
10:45 pm-9:22 am
1 stop7h 37m
Columbia Metropolitan
Wed 7/15
1:47 pm-8:05 pm
1 stop9h 18m
$379
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Francisco with our price prediction graph.
SFO-CHS
SFO-GSP
SFO-CLT
SFO-MYR
SFO-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South Carolina
SFO-USSC
SFO-CHS
SFO-GSP
SFO-CLT
SFO-MYR
How far ahead should I book a flight from San Francisco to South Carolina?
To ensure you get the cheapest price possible for a flight from San Francisco to South Carolina, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from San Francisco to South Carolina?
Currently, July is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $136). Flying from San Francisco to South Carolina in March is currently the most expensive (average of $211). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated May 12, 2026.
Peruse reviews from past customers who have flown with Breeze Airways,Southwest, andDelta from San Francisco to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Boarding
8.3
Food
6.6
Comfort
8.2
Overall
8.1
Entertainment
6.6
Crew
8.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations
Alternative routes for San Francisco to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to South Carolina by cabin class
Find flights from San Francisco to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and South Carolina flights
Browse other San Francisco and South Carolina flight options. Last updated on May 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Francisco to South Carolina flights
Consider these flights traveling from San Francisco to South Carolina.
Top 6 airlines flying from San Francisco to South Carolina
Discover the top 6 airlines that operate flights from San Francisco to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$362 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$168 | Average$296 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$467 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$490 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$313 | Average$497 | FlexibilityNo cancel fee | On-time63% |