$116+ Cheap flights from San Francisco (SFO) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CHS
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Francisco to South Carolina
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Cheapest flights from San Francisco to South CarolinaExplore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:46 pm -
1 stop6h 50m
Sun 12/67:00 am -
1 stop8h 01m
Deal found 11/4![Breeze Airways logo]()
$213
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:36 pm -
1 stop7h 19m
Mon 12/146:10 am -
1 stop7h 59m
Deal found 11/4![Breeze Airways logo]()
$215
This Breeze Airways deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:54 am -
1 stop6h 40m
Tue 12/87:00 am -
1 stop8h 01m
Deal found 11/8![Breeze Airways logo]()
$226
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:54 am -
1 stop6h 40m
Fri 12/116:10 am -
1 stop7h 59m
Deal found 11/4![Breeze Airways logo]()
$228
This Breeze Airways deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:46 pm -
1 stop6h 50m
Tue 12/87:00 am -
1 stop8h 01m
Deal found 11/5![Breeze Airways logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm -
2 stops25h 06m
Wed 12/96:20 am -
1 stop8h 31m
Deal found 11/4![Multiple Airlines logo]()
$249
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:54 am -
1 stop6h 40m
Tue 11/177:00 am -
1 stop8h 01m
Deal found 11/4![Breeze Airways logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
2 stops33h 42m
Sun 12/67:00 am -
1 stop8h 01m
Deal found 11/6![Multiple Airlines logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:54 am -
1 stop6h 40m
Fri 12/186:10 am -
1 stop7h 59m
Deal found 11/6![Breeze Airways logo]()
$272
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:40 pm -
1 stop9h 01m
Mon 12/142:18 pm -
1 stop10h 26m
Deal found 11/5![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop8h 28m
Sat 12/510:27 am -
1 stop8h 06m
Deal found 11/4![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:59 pm -
1 stop9h 34m
Sat 12/125:18 pm -
1 stop8h 00m
Deal found 11/6![American Airlines logo]()
$393
Best flights from San Francisco to South CarolinaDiscover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:54 am -
1 stop6h 40m
Fri 12/116:10 am -
1 stop7h 59m
Deal found 11/4![Breeze Airways logo]()
$228
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/28:30 am -
1 stop9h 30m
Fri 12/45:08 am -
1 stop10h 19m
Deal found 11/4![American Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/278:00 am -
1 stop7h 16m
Tue 2/210:26 am -
1 stop9h 58m
Deal found 11/5![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop8h 28m
Sat 12/510:27 am -
1 stop8h 06m
Deal found 11/4![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:25 pm -
1 stop9h 40m
Sat 12/1210:35 am -
2 stops11h 45m
Deal found 11/5![Southwest logo]()
$395
This Alaska Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:45 pm -
2 stops21h 32m
Sun 12/66:20 pm -
1 stop18h 18m
Deal found 11/7![Alaska Airlines logo]()
$497
This JetBlue deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1810:54 am -
1 stop9h 46m
Sat 1/94:00 pm -
1 stop11h 13m
Deal found 11/6![JetBlue logo]()
$507
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1312:46 pm -
1 stop6h 50m
Wed 12/166:20 am -
1 stop8h 31m
Deal found 11/4![Breeze Airways logo]()
$320
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/2510:21 am -
2 stops10h 41m
Wed 1/271:05 pm -
1 stop8h 57m
Deal found 11/4![Delta logo]()
$379
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:35 am -
1 stop7h 34m
Mon 12/1410:28 am -
1 stop9h 22m
Deal found 11/4![United Airlines logo]()
$399
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:55 pm -
2 stops14h 10m
Mon 12/148:10 am -
2 stops12h 55m
Deal found 11/5![Southwest logo]()
$415
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:24 am -
1 stop9h 31m
Mon 2/16:12 am -
1 stop9h 38m
Deal found 11/8![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1011:10 pm -
1 stop7h 34m
Mon 12/146:15 am -
1 stop8h 21m
Deal found 11/4![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/278:00 am -
1 stop7h 16m
Mon 2/12:38 pm -
1 stop9h 20m
Deal found 11/5![Delta logo]()
$407
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/286:40 am -
2 stops9h 35m
Mon 2/18:00 am -
1 stop9h 00m
Deal found 11/8![Southwest logo]()
$428
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/118:00 am -
1 stop8h 58m
Tue 2/168:25 am -
1 stop8h 00m
Deal found 11/5![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:00 am -
1 stop7h 53m
Fri 1/154:25 pm -
1 stop9h 28m
Deal found 11/4![American Airlines logo]()
$457
This Breeze Airways deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:46 pm -
1 stop6h 50m
Mon 12/216:10 am -
1 stop7h 59m
Deal found 11/8![Breeze Airways logo]()
$469
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/226:40 am -
2 stops9h 35m
Mon 1/258:00 am -
1 stop9h 00m
Deal found 11/6![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:59 pm -
1 stop8h 09m
Sat 12/55:40 pm -
1 stop9h 19m
Deal found 11/6![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/298:10 am -
Nonstop5h 25m
Mon 5/36:43 pm -
1 stop8h 46m
Deal found 11/5![United Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:50 pm -
1 stop9h 46m
Wed 12/24:24 pm -
1 stop9h 24m
Deal found 11/4![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:20 am -
2 stops10h 40m
Fri 2/56:20 am -
2 stops10h 45m
Deal found 11/4![Southwest logo]()
$443
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:59 pm -
1 stop7h 25m
Sun 12/66:02 pm -
1 stop8h 57m
Deal found 11/6![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/3010:45 pm -
1 stop8h 07m
Thu 12/37:48 pm -
1 stop8h 42m
Deal found 11/4![United Airlines logo]()
$474
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/136:50 am -
2 stops11h 10m
Wed 12/167:30 am -
2 stops11h 20m
Deal found 11/4![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1910:21 am -
2 stops10h 41m
Wed 3/242:25 pm -
1 stop8h 12m
Deal found 11/5![Delta logo]()
$415
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/311:59 pm -
1 stop7h 08m
Mon 12/76:57 pm -
1 stop8h 02m
Deal found 11/7![Delta logo]()
$423
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:05 am -
2 stops11h 30m
Fri 12/114:00 pm -
2 stops11h 25m
Deal found 11/4![Southwest logo]()
$474
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/285:00 am -
1 stop7h 53m
Sun 1/314:25 pm -
1 stop9h 28m
Deal found 11/8![American Airlines logo]()
$595
Last-minute flights from San Francisco to South CarolinaDiscover last-minute flight deals from San Francisco to South Carolina. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to South Carolina. Data last updated November 9, 2026 and is based on user searches.
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1311:54 am -
1 stop6h 40m
Tue 11/177:00 am -
1 stop8h 01m
Deal found 11/4![Breeze Airways logo]()
$260
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:00 am -
1 stop8h 28m
Sat 12/510:27 am -
1 stop8h 06m
Deal found 11/4![United Airlines logo]()
$369
This Breeze Airways deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/112:46 pm -
1 stop6h 50m
Tue 12/87:00 am -
1 stop8h 01m
Deal found 11/5![Breeze Airways logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:30 pm -
2 stops25h 06m
Wed 12/96:20 am -
1 stop8h 31m
Deal found 11/4![Multiple Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:59 pm -
1 stop9h 08m
Fri 12/46:59 pm -
1 stop8h 00m
Deal found 11/5![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:59 pm -
1 stop9h 34m
Sat 12/125:18 pm -
1 stop8h 00m
Deal found 11/6![American Airlines logo]()
$393
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:46 pm -
1 stop6h 50m
Sun 12/67:00 am -
1 stop8h 01m
Deal found 11/4![Breeze Airways logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/39:06 pm -
2 stops33h 42m
Sun 12/67:00 am -
1 stop8h 01m
Deal found 11/6![Multiple Airlines logo]()
$265
This Breeze Airways deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:54 am -
1 stop6h 40m
Tue 12/87:00 am -
1 stop8h 01m
Deal found 11/8![Breeze Airways logo]()
$226
This Breeze Airways deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/411:54 am -
1 stop6h 40m
Fri 12/116:10 am -
1 stop7h 59m
Deal found 11/4![Breeze Airways logo]()
$228
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:36 pm -
1 stop7h 19m
Mon 12/146:10 am -
1 stop7h 59m
Deal found 11/4![Breeze Airways logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1111:54 am -
1 stop6h 40m
Fri 12/186:10 am -
1 stop7h 59m
Deal found 11/6![Breeze Airways logo]()
$272
One-way flights from San Francisco to South CarolinaSearch for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:36 pm -
1 stop7h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Breeze Airways logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/610:04 am -
2 stops21h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$155
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/92:22 pm -
3 stops38h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/1211:25 am -
3 stops43h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$173
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2611:59 pm -
1 stop7h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$185
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1610:40 pm -
1 stop8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:00 pm -
3 stops34h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$188
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2411:17 am -
1 stop8h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![American Airlines logo]()
$189
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/154:55 pm -
2 stops14h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Southwest logo]()
$190
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:10 am -
2 stops9h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Southwest logo]()
$190
This Breeze Airways deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1812:36 pm -
1 stop7h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Breeze Airways logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/1312:35 pm -
2 stops17h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$193
Find flight deals from San Francisco to South Carolina
Keep the following information in mind while searching for San Francisco to South Carolina flight deals. Data was last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $200 (Kiwi.com) |
One-way from | $116 (Breeze Airways) |
Popular in | March |
Cheapest in | February |
Average price | $562 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoMyrtle Beach
SFO San Francisco - MYR Myrtle Beach Intl
SFOMYR
San Francisco
Tue 12/15
6:00 am-6:03 pm
1 stop9h 03m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Thu 12/17
10:34 pm-9:28 am
1 stop7h 54m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San FranciscoMyrtle Beach
SFO San Francisco - MYR Myrtle Beach Intl
SFOMYR
San Francisco
Thu 11/26
11:59 pm-10:07 am
1 stop7h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 12/16
10:40 pm-10:12 am
1 stop8h 32m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San FranciscoCharleston
SFO San Francisco - CHS Charleston
SFOCHS
San Francisco
Thu 12/24
11:17 am-10:37 pm
1 stop8h 20m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$189
San FranciscoMyrtle Beach
SFO San Francisco - MYR Myrtle Beach Intl
SFOMYR
San Francisco
Tue 12/15
4:55 pm-10:05 am
2 stops14h 10m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
San FranciscoGreenville
SFO San Francisco - GSP Greenville
SFOGSP
San Francisco
Wed 12/9
6:10 am-6:10 pm
2 stops9h 00m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$190
San FranciscoCharleston
SFO San Francisco - CHS Charleston
SFOCHS
San Francisco
Wed 11/18
12:36 pm-10:55 pm
1 stop7h 19m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$193
San FranciscoCharleston
SFO San Francisco - CHS Charleston
SFOCHS
San Francisco
Thu 12/31
7:30 am-6:48 pm
1 stop8h 18m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$194
San FranciscoMyrtle Beach
SFO San Francisco - MYR Myrtle Beach Intl
SFOMYR
San Francisco
Tue 12/1
11:59 pm-10:07 am
1 stop7h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$197
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Francisco with our price prediction graph.
SFO-CHS
SFO-MYR
SFO-GSP
SFO-HHH
SFO-CAE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South Carolina
SFO-USSC
SFO-CHS
SFO-MYR
SFO-GSP
SFO-HHH
What is the cheapest month to book a flight from San Francisco to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $406). Flying from San Francisco to South Carolina in November is currently the most expensive (average of $571). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SFO to SC?
Find hourly flight availability from San Francisco to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2026.
When flying from San Francisco to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from San Francisco to South Carolina
Explore weekly flight availability from San Francisco to South Carolina. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 9, 2026.
The most flights from SFO to USSC are scheduled on a Monday (1 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from San Francisco to South Carolina?
Airfare is below average for this route at the moment.
San Francisco to South Carolina flights typically cost between $370 and $728 in December.The cheapest round-trip price found within the last 5 days was $213 on Breeze Airways (Dec 3-Dec 6).
How far ahead should I book a flight from San Francisco to South Carolina?
To ensure you get the cheapest price possible for a flight from San Francisco to South Carolina, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated November 9, 2026.
Peruse reviews from past customers who have flown with Breeze Airways,Southwest, andDelta from San Francisco to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Food
6.7
Crew
8.8
Entertainment
6.8
Boarding
8.4
Overall
8.2
Comfort
8.2
Reviews
1 / 18
10.0
ExcellentJames,Oct 2026
RSW - RDU
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Francisco to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to South Carolina by cabin class
Find flights from San Francisco to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and South Carolina flights
Browse other San Francisco and South Carolina flight options. Last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Francisco to South Carolina flights
Consider these flights traveling from San Francisco to South Carolina.
Top 6 airlines flying from San Francisco to South Carolina
Discover the top 6 airlines that operate flights from San Francisco to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$362 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$171 | Average$380 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$479 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$262 | Average$484 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$577 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$322 | Average$498 | FlexibilityNo cancel fee | On-time63% |