$102+ Cheap flights from San Francisco (SFO) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — CHS
Jul 27 — Aug 31
Round-trip
1 adult, Economy
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Find cheap flights from San Francisco to South Carolina with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Francisco to South CarolinaExplore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
Explore the most affordable flight options available from San Francisco to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Sun 8/307:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2112:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Sat 8/296:30 am
CHS
- SFO
1 stop8h 07m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$230
This Breeze Airways deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Fri 8/217:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/27![Breeze Airways logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:36 pm
SFO
- CHS
1 stop7h 19m
Breeze Airways
Tue 9/297:00 am
CHS
- SFO
1 stop8h 01m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$239
This CheapOair deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Mon 8/177:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$265
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Sun 9/67:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$266
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:30 pm
SFO
- SAV
1 stop9h 40m
United Airlines
Sat 9/123:55 pm
SAV
- SFO
1 stop8h 15m
United Airlines
Deal found 6/26![United Airlines logo]()
$301
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:30 pm
SFO
- SAV
1 stop8h 40m
Southwest
Sat 9/121:10 pm
SAV
- SFO
2 stops10h 25m
Southwest
Deal found 6/26![Southwest logo]()
$306
This United Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/125:00 am
SFO
- GSP
1 stop9h 02m
United Airlines
Wed 8/196:30 am
GSP
- SFO
1 stop7h 55m
United Airlines
Deal found 6/27![United Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:40 am
SFO
- GSP
2 stops10h 15m
Southwest
Wed 8/1911:00 am
GSP
- SFO
1 stop8h 25m
Southwest
Deal found 6/27![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:30 pm
SFO
- SAV
1 stop9h 15m
Southwest
Tue 8/116:45 am
SAV
- SFO
2 stops10h 55m
Southwest
Deal found 6/25![Southwest logo]()
$314
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:50 am
SFO
- GSP
2 stops11h 05m
Southwest
Tue 8/117:00 am
GSP
- SFO
1 stop12h 25m
Southwest
Deal found 6/25![Southwest logo]()
$319
Best flights from San Francisco to South CarolinaDiscover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
Discover carefully curated flight deals from San Francisco to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Sun 8/307:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$203
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:30 pm
SFO
- SAV
1 stop9h 15m
Southwest
Tue 8/116:45 am
SAV
- SFO
2 stops10h 55m
Southwest
Deal found 6/25![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:30 am
SFO
- GSP
1 stop8h 19m
Delta
Wed 11/185:40 am
GSP
- SFO
1 stop7h 52m
Delta
Deal found 6/23![Delta logo]()
$363
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:45 pm
SFO
- GSP
1 stop8h 01m
United Airlines
Wed 11/186:30 am
GSP
- SFO
1 stop8h 01m
United Airlines
Deal found 6/22![United Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:30 am
SFO
- AGS
1 stop6h 59m
American Airlines
Tue 11/107:00 am
AGS
- SFO
1 stop9h 16m
American Airlines
Deal found 6/25![American Airlines logo]()
$419
This JetBlue deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:59 am
SFO
- CLT
1 stop9h 21m
JetBlue
Tue 9/13:10 pm
CLT
- SFO
1 stop11h 41m
JetBlue
Deal found 6/23![JetBlue logo]()
$480
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Mon 8/177:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$268
This Southwest deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/811:05 pm
SFO
- MYR
1 stop12h 00m
Southwest
Sat 8/1511:55 am
MYR
- SFO
1 stop7h 30m
Southwest
Deal found 6/26![Southwest logo]()
$344
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:40 am
SFO
- HHH
2 stops11h 39m
Delta
Wed 10/2812:00 pm
HHH
- SFO
1 stop8h 11m
Delta
Deal found 6/27![Delta logo]()
$366
This Breeze Airways deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Sun 9/67:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/27![Breeze Airways logo]()
$346
This Delta deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SFO
- CAE
1 stop8h 20m
Delta
Sat 8/296:11 am
CAE
- SFO
1 stop7h 06m
Delta
Deal found 6/25![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:30 pm
SFO
- SAV
1 stop8h 40m
Southwest
Sat 8/291:10 pm
SAV
- SFO
2 stops10h 25m
Southwest
Deal found 6/22![Southwest logo]()
$370
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:21 am
SFO
- SAV
2 stops12h 02m
United Airlines
Sat 9/512:59 pm
SAV
- SFO
1 stop8h 25m
United Airlines
Deal found 6/26![United Airlines logo]()
$416
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:05 am
SFO
- MYR
1 stop8h 25m
American Airlines
Thu 8/135:15 pm
MYR
- SFO
2 stops9h 56m
American Airlines
Deal found 6/23![American Airlines logo]()
$423
This Delta deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:15 pm
SFO
- CAE
1 stop7h 02m
Delta
Mon 8/245:40 am
CAE
- SFO
1 stop7h 37m
Delta
Deal found 6/24![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/48:15 am
SFO
- GSP
2 stops9h 25m
Southwest
Wed 11/187:05 am
GSP
- SFO
2 stops9h 55m
Southwest
Deal found 6/22![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2710:45 pm
SFO
- GSP
1 stop8h 01m
United Airlines
Sat 10/312:20 pm
GSP
- SFO
1 stop10h 04m
United Airlines
Deal found 6/26![United Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1612:00 pm
SFO
- FLO
1 stop7h 58m
American Airlines
Thu 9/245:09 am
FLO
- SFO
1 stop7h 38m
American Airlines
Deal found 6/27![American Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:40 am
SFO
- GSP
2 stops10h 25m
Southwest
Wed 10/216:50 am
GSP
- SFO
2 stops10h 25m
Southwest
Deal found 6/22![Southwest logo]()
$373
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:40 am
SFO
- HHH
2 stops11h 39m
Delta
Wed 10/2812:00 pm
HHH
- SFO
2 stops9h 36m
Delta
Deal found 6/23![Delta logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:45 am
SFO
- MYR
2 stops10h 53m
American Airlines
Sat 9/1212:10 pm
MYR
- SFO
2 stops9h 52m
American Airlines
Deal found 6/26![American Airlines logo]()
$427
This Breeze Airways deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Tue 7/147:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$428
This United Airlines deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/315:00 am
SFO
- CHS
1 stop10h 05m
United Airlines
Tue 11/34:22 pm
CHS
- SFO
1 stop9h 39m
United Airlines
Deal found 6/26![United Airlines logo]()
$433
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:15 am
SFO
- GSP
2 stops8h 50m
Southwest
Mon 12/148:05 am
GSP
- SFO
1 stop8h 45m
Southwest
Deal found 6/23![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2312:40 am
SFO
- HHH
2 stops11h 39m
Delta
Fri 10/3012:00 pm
HHH
- SFO
2 stops11h 18m
Delta
Deal found 6/23![Delta logo]()
$379
This Breeze Airways deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1612:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Mon 7/207:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/22![Breeze Airways logo]()
$436
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:20 pm
SFO
- FLO
1 stop7h 17m
American Airlines
Wed 7/295:17 am
FLO
- SFO
1 stop10h 02m
American Airlines
Deal found 6/24![American Airlines logo]()
$457
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:45 pm
SFO
- SAV
1 stop7h 36m
Delta
Mon 8/105:18 pm
SAV
- SFO
1 stop9h 29m
Delta
Deal found 6/23![Delta logo]()
$381
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:50 am
SFO
- GSP
2 stops11h 05m
Southwest
Mon 8/107:00 am
GSP
- SFO
2 stops10h 40m
Southwest
Deal found 6/23![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am
SFO
- SAV
1 stop7h 40m
United Airlines
Wed 12/97:00 pm
SAV
- SFO
1 stop9h 16m
United Airlines
Deal found 6/22![United Airlines logo]()
$475
Last-minute flights from San Francisco to South CarolinaDiscover last-minute flight deals from San Francisco to South Carolina. Data last updated June 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Francisco to South Carolina. Data last updated June 27, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:00 am
SFO
- CLT
1 stop12h 19m
Frontier
Tue 7/216:48 pm
CLT
- SFO
2 stops27h 30m
Frontier
Deal found 6/22![Frontier logo]()
$386
This Expedia deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Mon 7/137:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$371
This Breeze Airways deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Tue 7/217:25 am
CHS
- SFO
1 stop7h 37m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$334
This CheapOair deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:22 pm
SFO
- CHS
1 stop7h 27m
Breeze Airways
Wed 7/226:30 am
CHS
- SFO
1 stop8h 07m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$376
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2012:26 am
SFO
- GSP
1 stop9h 43m
American Airlines
Tue 7/285:28 pm
GSP
- SFO
1 stop10h 15m
American Airlines
Deal found 6/23![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:24 am
SFO
- SAV
1 stop9h 00m
American Airlines
Tue 7/287:01 am
SAV
- SFO
1 stop9h 05m
American Airlines
Deal found 6/23![American Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:47 pm
SFO
- CHS
1 stop7h 00m
Multiple Airlines
Fri 7/319:37 pm
CHS
- SFO
2 stops29h 46m
Multiple Airlines
Deal found 6/25![Multiple Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:15 am
SFO
- SAV
1 stop7h 55m
Southwest
Tue 7/284:50 pm
SAV
- SFO
2 stops9h 30m
Southwest
Deal found 6/23![Southwest logo]()
$370
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:25 am
SFO
- GSP
2 stops8h 40m
Southwest
Tue 7/287:00 am
GSP
- SFO
2 stops9h 40m
Southwest
Deal found 6/23![Southwest logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Fri 7/317:00 am
CHS
- SFO
1 stop7h 33m
Breeze Airways
Deal found 6/25![Breeze Airways logo]()
$388
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:29 am
SFO
- GSP
1 stop8h 07m
American Airlines
Tue 7/288:01 pm
GSP
- SFO
1 stop7h 42m
American Airlines
Deal found 6/24![American Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:29 am
SFO
- GSP
1 stop8h 07m
American Airlines
Wed 7/295:28 pm
GSP
- SFO
1 stop10h 15m
American Airlines
Deal found 6/22![American Airlines logo]()
$386
One-way flights from San Francisco to South CarolinaSearch for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
Search for one-way flight options from San Francisco to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 27, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2812:18 pm
SFO
- CHS
1 stop6h 48m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$102
This Breeze Airways deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/612:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Deal found 6/26![Breeze Airways logo]()
$125
This Breeze Airways deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1712:46 pm
SFO
- CHS
1 stop6h 50m
Breeze Airways
Deal found 6/24![Breeze Airways logo]()
$132
This Breeze Airways deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:46 pm
SFO
- CHS
1 stop6h 50m
Breeze Airways
Deal found 6/22![Breeze Airways logo]()
$151
This Delta deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:00 am
SFO
- SAV
1 stop7h 54m
Delta
Deal found 6/27![Delta logo]()
$151
This Southwest deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/179:40 pm
SFO
- CLT
1 stop9h 30m
Southwest
Deal found 6/25![Southwest logo]()
$154
This Frontier deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:35 pm
SFO
- CLT
1 stop13h 40m
Frontier
Deal found 6/26![Frontier logo]()
$155
This Southwest deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:00 am
SFO
- SAV
2 stops11h 35m
Southwest
Deal found 6/27![Southwest logo]()
$156
This Super.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:38 pm
SFO
- CLT
1 stop29h 41m
Frontier
Deal found 6/25![Frontier logo]()
$156
This CheapOair deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2812:38 pm
SFO
- CLT
1 stop29h 41m
Frontier
Deal found 6/25![Frontier logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1112:47 pm
SFO
- CHS
1 stop7h 00m
Breeze Airways
Deal found 6/23![Breeze Airways logo]()
$159
This Frontier deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 am
SFO
- CLT
1 stop12h 19m
Frontier
Deal found 6/24![Frontier logo]()
$159
Find flight deals from San Francisco to South Carolina
Keep the following information in mind while searching for San Francisco to South Carolina flight deals. Data was last updated June 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $203 (Breeze Airways) |
One-way from | $102 (Breeze Airways) |
Popular in | March |
Cheapest in | November |
Average price | $548 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Francisco to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from San Francisco to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Fri 8/28
12:18 pm-10:06 pm
1 stop6h 48m
Charleston
Sun 8/30
7:25 am-12:02 pm
1 stop7h 37m
$203
Quickest round-trip
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Fri 8/14
12:18 pm-10:06 pm
1 stop6h 48m
Charleston
Mon 8/17
7:00 am-11:33 am
1 stop7h 33m
$268
San FranciscoSavannah
SFO - SAV
SFOSAV
San Francisco
Thu 8/6
10:30 pm-10:45 am
1 stop9h 15m
Savannah/Hilton Head
Tue 8/11
6:45 am-2:40 pm
2 stops10h 55m
$314
San FranciscoMyrtle Beach
SFO - MYR
SFOMYR
San Francisco
Sat 8/8
11:05 pm-2:05 pm
1 stop12h 00m
Myrtle Beach Intl
Sat 8/15
11:55 am-4:25 pm
1 stop7h 30m
$344
San FranciscoCharleston
SFO - CHS
SFOCHS
San Francisco
Thu 9/3
12:47 pm-10:47 pm
1 stop7h 00m
Charleston
Sun 9/6
7:25 am-12:02 pm
1 stop7h 37m
$346
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 11/4
7:30 am-6:49 pm
1 stop8h 19m
Greenville
Wed 11/18
5:40 am-10:32 am
1 stop7h 52m
$363
San FranciscoGreenville
SFO - GSP
SFOGSP
San Francisco
Wed 11/4
10:45 pm-9:46 am
1 stop8h 01m
Greenville
Wed 11/18
6:30 am-11:31 am
1 stop8h 01m
$363
San FranciscoHilton Head Island
SFO - HHH
SFOHHH
San Francisco
Tue 10/20
12:40 am-3:19 pm
2 stops11h 39m
Hilton Head Island
Wed 10/28
12:00 pm-5:11 pm
1 stop8h 11m
$366
San FranciscoColumbia
SFO - CAE
SFOCAE
San Francisco
Wed 8/26
6:00 am-5:20 pm
1 stop8h 20m
Columbia Metropolitan
Sat 8/29
6:11 am-10:17 am
1 stop7h 06m
$369
San FranciscoColumbia
SFO - CAE
SFOCAE
San Francisco
Thu 8/20
11:15 pm-9:17 am
1 stop7h 02m
Columbia Metropolitan
Mon 8/24
5:40 am-10:17 am
1 stop7h 37m
$369
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Francisco to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Francisco with our price prediction graph.
SFO-CHS
SFO-GSP
SFO-SAV
SFO-CLT
SFO-AGS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Francisco to South Carolina
SFO-USSC
SFO-CHS
SFO-GSP
SFO-SAV
SFO-CLT
What is the cheapest month to book a flight from San Francisco to South Carolina?
Currently, December is the cheapest month in which you can book a flight from San Francisco to South Carolina (average of $136). Flying from San Francisco to South Carolina in April is currently the most expensive (average of $254). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Francisco to South Carolina?
How far ahead should I book a flight from San Francisco to South Carolina?
To ensure you get the cheapest price possible for a flight from San Francisco to South Carolina, you should look to book at least 41 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 27, 2026.
Peruse reviews from past customers who have flown with Breeze Airways,Southwest, andDelta from San Francisco to South Carolina to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Comfort
8.2
Entertainment
6.7
Overall
8.2
Crew
8.8
Boarding
8.4
Food
6.7
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from San Francisco to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for San Francisco to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Francisco to South Carolina by cabin class
Find flights from San Francisco to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Francisco and South Carolina flights
Browse other San Francisco and South Carolina flight options. Last updated on June 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Francisco to South Carolina flights
Consider these flights traveling from San Francisco to South Carolina.
Top 6 airlines flying from San Francisco to South Carolina
Discover the top 6 airlines that operate flights from San Francisco to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$166 | Average$362 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$170 | Average$308 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$250 | Average$499 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$256 | Average$494 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$259 | Average$466 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$352 | Average$531 | FlexibilityNo cancel fee | On-time63% |