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$100+ Cheap flights from South Carolina to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
Jul 24 — Jul 311
Fri 7/24
Fri 7/31
1 adult, Economy
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Cheap flight deals from South Carolina to San Francisco

Cheapest flights from South Carolina to San Francisco
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 24, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:00 am
CHS
-
SFO
1 stop7h 33m
Breeze Airways
Tue 9/112:47 pm
SFO
-
CHS
1 stop7h 00m
Breeze Airways
Deal found 6/23$222
This Breeze Airways deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:30 am
CHS
-
SFO
1 stop8h 07m
Breeze Airways
Mon 8/3112:18 pm
SFO
-
CHS
1 stop6h 48m
Breeze Airways
Deal found 6/22$227
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:25 am
CHS
-
SFO
1 stop7h 37m
Breeze Airways
Tue 9/112:47 pm
SFO
-
CHS
1 stop7h 00m
Breeze Airways
Deal found 6/23$233
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:30 am
CHS
-
SFO
1 stop8h 07m
Breeze Airways
Sun 9/612:47 pm
SFO
-
CHS
1 stop7h 00m
Breeze Airways
Deal found 6/22$250
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:00 am
CHS
-
SFO
1 stop7h 33m
Multiple Airlines
Mon 8/317:30 pm
SFO
-
CHS
2 stops11h 07m
Multiple Airlines
Deal found 6/23$278
This Breeze Airways deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:25 am
CHS
-
SFO
1 stop7h 37m
Breeze Airways
Wed 8/2612:22 pm
SFO
-
CHS
1 stop7h 27m
Breeze Airways
Deal found 6/22$282
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/307:25 am
CHS
-
SFO
1 stop7h 37m
Multiple Airlines
Sun 8/3010:35 pm
SFO
-
CHS
2 stops32h 02m
Multiple Airlines
Deal found 6/23$296
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:25 am
CHS
-
SFO
1 stop7h 37m
Breeze Airways
Tue 9/17:28 pm
SFO
-
CHS
2 stops34h 10m
Breeze Airways
Deal found 6/23$297
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:00 am
CHS
-
SFO
1 stop8h 01m
Breeze Airways
Fri 9/2511:54 am
SFO
-
CHS
1 stop6h 40m
Breeze Airways
Deal found 6/20$303
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:15 am
SAV
-
SFO
1 stop7h 47m
Multiple Airlines
Sat 9/127:30 pm
SFO
-
SAV
2 stops11h 06m
Multiple Airlines
Deal found 6/24$348
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:15 pm
MYR
-
SFO
1 stop10h 03m
American Airlines
Sat 8/2211:40 pm
SFO
-
MYR
1 stop9h 51m
American Airlines
Deal found 6/23$363
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:28 pm
GSP
-
SFO
1 stop8h 00m
American Airlines
Tue 8/45:29 am
SFO
-
GSP
1 stop8h 07m
American Airlines
Deal found 6/20$363

Find flight deals from South Carolina to San Francisco

Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated June 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$222
(Kiwi.com)

One-way from

$100
(Kiwi.com)

Popular in

April

Cheapest in

October

Average price

$587
Provider with most accurate pricing for Myrtle Beach Intl-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-San Francisco flights.
Search Deals
From South Carolina to San Francisco
Search Deals
One-way flight from South Carolina to San Francisco
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Sat 9/12

6:20 am-11:51 am

1 stop8h 31m

San Francisco

Sat 9/19

12:36 pm-10:55 pm

1 stop7h 19m

$345

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Fri 9/18

6:10 am-11:09 am

1 stop7h 59m

San Francisco

Fri 9/25

11:54 am-9:34 pm

1 stop6h 40m

$348

SavannahSan Francisco

SAV - SFO

SAVSFO

Savannah/Hilton Head

Tue 9/1

3:11 pm-7:39 pm

1 stop7h 28m

San Francisco

Sat 9/5

6:00 am-5:30 pm

1 stop8h 30m

$365

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Sat 8/15

1:40 pm-8:35 pm

1 stop9h 55m

San Francisco

Sat 8/22

11:40 pm-2:10 pm

2 stops11h 30m

$368

Myrtle BeachSan Francisco

MYR - SFO

MYRSFO

Myrtle Beach Intl

Wed 9/23

2:25 pm-11:15 pm

2 stops11h 50m

San Francisco

Tue 9/29

10:30 pm-10:05 am

1 stop8h 35m

$368

GreenvilleSan Francisco

GSP - SFO

GSPSFO

Greenville

Wed 10/21

10:50 am-3:15 pm

1 stop7h 25m

San Francisco

Wed 10/21

10:50 pm-12:20 pm

1 stop10h 30m

$368

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Fri 8/21

3:59 pm-10:40 pm

1 stop9h 41m

San Francisco

Tue 8/25

11:28 pm-12:19 pm

1 stop9h 51m

$369

ColumbiaSan Francisco

CAE - SFO

CAESFO

Columbia Metropolitan

Wed 10/14

7:46 pm-12:59 am

1 stop8h 13m

San Francisco

Mon 10/19

10:40 pm-9:47 am

1 stop8h 07m

$369

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Wed 8/5

6:00 am-11:38 am

1 stop8h 38m

San Francisco

Wed 8/12

5:00 am-3:28 pm

1 stop7h 28m

$369

CharlestonSan Francisco

CHS - SFO

CHSSFO

Charleston

Wed 7/15

6:00 am-11:38 am

1 stop8h 38m

San Francisco

Tue 7/21

9:30 pm-10:07 am

1 stop9h 37m

$369

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/21

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to San Francisco

What is the cheapest month to book a flight from South Carolina to San Francisco?

Currently, August is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $99). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from South Carolina to San Francisco?

How far ahead should I book a flight from South Carolina to San Francisco?

Booking 32 days in advance of your planned departure date is, on average, the best time to get cheap flights from South Carolina to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from South Carolina?

    Most people fly into San Francisco (SFO) if they book a flight to San Francisco from South Carolina. San Francisco is conveniently located just 11.0 mi from San Francisco’s city center.

  • How long is the flight from South Carolina to San Francisco?

    Breeze Airways, Delta, and Southwest can get you from South Carolina to San Francisco in just under 7h 28m. Your travel time can differ by up to 2h 27m. The distance between South Carolina and San Francisco is about 2344 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to San Francisco one-way?

    One-way options have recently been found by users for as low as $75 on Breeze Airways. Other airlines that offer cheap prices include American Airlines from $106 and JetBlue from $121 one-way.

  • What are the most popular routes from South Carolina to San Francisco?

    The most popular route from South Carolina to San Francisco is Charlotte Douglas - San Francisco. You may also consider Charleston - San Francisco or Greenville - San Francisco.

  • Can I find deals for flights from South Carolina to San Francisco that include hotel bookings?

    Yes. In addition to deals on South Carolina to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to San Francisco.

  • Can I find deals for business class flights from South Carolina to San Francisco?

    Yes. Cheapflights offers flight deals from South Carolina to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to San Francisco?

    Currently, August is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $99). Flying from South Carolina to San Francisco in March is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Clara
Santa Cruz
Fairfield
Burlingame
Rancho Cordova
Roseville
Cupertino
Emeryville
Watsonville
Newark
San Bruno
Hayward
San Ramon
San Carlos
Redwood City
Turlock
Daly City
Sunnyvale
Vallejo

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to San Francisco

Discover the top 6 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 24, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$144Average$291FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$199Average$471FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$460FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$256Average$474FlexibilityNo cancel feeOn-time69%
JetBlueCheapest$276Average$282FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$301Average$526FlexibilityNo cancel feeOn-time63%

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