$98+ Cheap flights from South Carolina to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — SFO
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to San Francisco
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Cheapest flights from South Carolina to San FranciscoExplore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from South Carolina to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Wed 12/912:36 pm -
1 stop7h 19m
Deal found 11/5![Breeze Airways logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/7![Breeze Airways logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Fri 12/1111:54 am -
1 stop6h 40m
Deal found 11/6![Breeze Airways logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Tue 12/812:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Sat 12/1212:36 pm -
1 stop7h 19m
Deal found 11/6![Breeze Airways logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop8h 01m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am -
1 stop8h 01m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$209
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:00 pm -
1 stop8h 49m
Wed 12/210:59 pm -
1 stop8h 08m
Deal found 11/5![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:18 pm -
1 stop9h 40m
Thu 12/1011:40 pm -
1 stop7h 12m
Deal found 11/5![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:05 am -
2 stops10h 35m
Tue 12/89:25 pm -
1 stop10h 20m
Deal found 11/5![Southwest logo]()
$374
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:05 am -
1 stop8h 45m
Thu 12/107:15 am -
2 stops10h 35m
Deal found 11/5![Southwest logo]()
$382
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:04 pm -
1 stop7h 50m
Tue 12/85:00 am -
1 stop7h 17m
Deal found 11/8![United Airlines logo]()
$393
Best flights from South Carolina to San FranciscoDiscover carefully curated flight deals from South Carolina to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from South Carolina to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Wed 12/96:39 pm -
2 stops13h 24m
Deal found 11/5![Multiple Airlines logo]()
$239
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:04 pm -
1 stop7h 50m
Tue 12/85:00 am -
1 stop7h 17m
Deal found 11/5![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:05 am -
1 stop8h 45m
Thu 12/107:15 am -
2 stops10h 35m
Deal found 11/5![Southwest logo]()
$382
This JetBlue deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/112:00 pm -
1 stop11h 24m
Wed 1/138:00 am -
1 stop8h 18m
Deal found 11/7![JetBlue logo]()
$388
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/310:57 am -
1 stop10h 17m
Sun 12/610:59 pm -
1 stop9h 14m
Deal found 11/6![Delta logo]()
$400
This Breeze Airways deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:00 am -
1 stop8h 01m
Thu 12/3112:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$418
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/61:50 pm -
2 stops12h 19m
Sat 1/97:00 am -
2 stops10h 55m
Deal found 11/8![American Airlines logo]()
$425
This Alaska Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:20 pm -
1 stop18h 18m
Wed 12/96:00 am -
1 stop8h 17m
Deal found 11/5![Alaska Airlines logo]()
$485
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/35:25 pm -
1 stop10h 04m
Wed 4/76:35 am -
1 stop7h 25m
Deal found 11/5![United Airlines logo]()
$409
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/288:00 am -
1 stop9h 00m
Tue 2/25:00 pm -
2 stops14h 00m
Deal found 11/7![Southwest logo]()
$413
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:53 am -
1 stop8h 31m
Sun 12/1311:59 pm -
1 stop6h 28m
Deal found 11/8![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/65:12 pm -
1 stop8h 41m
Sun 1/107:00 am -
2 stops10h 55m
Deal found 11/8![American Airlines logo]()
$455
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/112:33 pm -
1 stop9h 16m
Tue 2/166:00 am -
1 stop9h 08m
Deal found 11/8![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:35 am -
2 stops11h 20m
Wed 12/96:10 am -
2 stops10h 25m
Deal found 11/5![Southwest logo]()
$422
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:37 pm -
1 stop8h 53m
Fri 12/255:00 am -
1 stop7h 16m
Deal found 11/7![United Airlines logo]()
$433
This Breeze Airways deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/227:00 am -
1 stop8h 01m
Fri 11/2711:54 am -
1 stop6h 40m
Deal found 11/8![Breeze Airways logo]()
$489
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/77:00 am -
1 stop8h 42m
Sun 1/1011:53 pm -
1 stop8h 37m
Deal found 11/9![Delta logo]()
$419
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:05 am -
1 stop8h 45m
Mon 12/148:00 am -
2 stops9h 50m
Deal found 11/8![Southwest logo]()
$428
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:06 pm -
1 stop8h 47m
Sat 2/65:00 am -
1 stop8h 36m
Deal found 11/8![American Airlines logo]()
$489
This Alaska Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:53 pm -
2 stops23h 45m
Sun 12/136:00 am -
2 stops26h 31m
Deal found 11/8![Alaska Airlines logo]()
$559
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:57 am -
1 stop10h 17m
Mon 12/711:59 pm -
1 stop8h 14m
Deal found 11/9![Delta logo]()
$433
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:10 pm -
1 stop8h 15m
Mon 1/116:40 am -
2 stops9h 35m
Deal found 11/8![Southwest logo]()
$434
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/242:52 pm -
1 stop9h 37m
Mon 11/3011:30 pm -
1 stop8h 33m
Deal found 11/9![United Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/314:13 pm -
2 stops10h 11m
Mon 1/412:28 am -
1 stop8h 47m
Deal found 11/7![American Airlines logo]()
$500
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:40 am -
2 stops9h 25m
Mon 12/149:25 pm -
1 stop10h 20m
Deal found 11/7![Southwest logo]()
$438
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:18 pm -
1 stop9h 38m
Mon 12/710:40 pm -
1 stop8h 32m
Deal found 11/10![Delta logo]()
$443
This Trip.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/212:41 pm -
2 stops12h 54m
Tue 12/2212:53 am -
2 stops28h 57m
Deal found 11/9![Multiple Airlines logo]()
$693
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/71:53 pm -
1 stop7h 53m
Sun 1/1011:23 pm -
2 stops10h 54m
Deal found 11/9![American Airlines logo]()
$542
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/55:38 am -
1 stop10h 04m
Sun 1/1010:25 pm -
1 stop7h 52m
Deal found 11/9![Delta logo]()
$450
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:45 am -
2 stops9h 20m
Thu 12/109:25 pm -
1 stop9h 55m
Deal found 11/6![Southwest logo]()
$453
Last-minute flights from South Carolina to San FranciscoDiscover last-minute flight deals from South Carolina to San Francisco. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to San Francisco. Data last updated November 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/264:00 pm -
1 stop8h 49m
Wed 12/210:59 pm -
1 stop8h 08m
Deal found 11/5![Delta logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/34:18 pm -
1 stop9h 40m
Thu 12/1011:40 pm -
1 stop7h 12m
Deal found 11/5![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:05 am -
1 stop8h 45m
Thu 12/107:15 am -
2 stops10h 35m
Deal found 11/5![Southwest logo]()
$382
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:05 am -
2 stops10h 35m
Tue 12/89:25 pm -
1 stop10h 20m
Deal found 11/5![Southwest logo]()
$374
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/52:04 pm -
1 stop7h 50m
Tue 12/85:00 am -
1 stop7h 17m
Deal found 11/8![United Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am -
1 stop8h 01m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Wed 12/912:36 pm -
1 stop7h 19m
Deal found 11/5![Breeze Airways logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/7![Breeze Airways logo]()
$186
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Fri 12/1111:54 am -
1 stop6h 40m
Deal found 11/6![Breeze Airways logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Tue 12/812:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:10 am -
1 stop7h 59m
Sat 12/1212:36 pm -
1 stop7h 19m
Deal found 11/6![Breeze Airways logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop8h 01m
Thu 12/1012:46 pm -
1 stop6h 50m
Deal found 11/6![Breeze Airways logo]()
$205
One-way flights from South Carolina to San FranciscoSearch for one-way flight options from South Carolina to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from South Carolina to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Breeze Airways deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:00 am -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Breeze Airways logo]()
$106
This Breeze Airways deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:20 am -
1 stop8h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:42 pm -
3 stops45h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/113:17 pm -
3 stops44h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$140
This Breeze Airways deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Breeze Airways logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/64:22 pm -
2 stops21h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/197:05 am -
2 stops32h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:00 am -
1 stop8h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Breeze Airways logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/110:17 am -
2 stops33h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$182
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1612:18 pm -
1 stop9h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:03 pm -
3 stops33h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$194
Find flight deals from South Carolina to San Francisco
Keep the following information in mind while searching for South Carolina to San Francisco flight deals. Data was last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $169 (Kiwi.com) |
One-way from | $98 (Breeze Airways) |
Popular in | April |
Cheapest in | January |
Average price | $642 |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from South Carolina to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonSan Francisco
CHS Charleston - SFO San Francisco
CHSSFO
Charleston
Sun 12/6
7:00 am-12:01 pm
1 stop8h 01m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$108
CharlestonSan Francisco
CHS Charleston - SFO San Francisco
CHSSFO
Charleston
Sat 12/5
6:20 am-11:51 am
1 stop8h 31m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$117
CharlestonSan Francisco
CHS Charleston - SFO San Francisco
CHSSFO
Charleston
Fri 12/4
6:10 am-11:09 am
1 stop7h 59m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$169
CharlestonSan Francisco
CHS Charleston - SFO San Francisco
CHSSFO
Charleston
Sat 11/21
6:20 am-11:51 am
1 stop8h 31m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$180
Quickest round-trip
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Fri 12/18
8:14 am-12:47 pm
1 stop7h 33m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$185
CharlestonSan Francisco
CHS Charleston - SFO San Francisco
CHSSFO
Charleston
Fri 12/11
1:53 pm-11:26 pm
1 stop12h 33m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$189
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Sat 12/5
10:18 am-5:41 pm
1 stop10h 23m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$197
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Tue 12/8
6:59 pm-11:55 pm
1 stop7h 56m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$197
Myrtle BeachSan Francisco
MYR Myrtle Beach Intl - SFO San Francisco
MYRSFO
Myrtle Beach Intl
Wed 12/16
10:52 am-5:24 pm
1 stop9h 32m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$197
GreenvilleSan Francisco
GSP Greenville - SFO San Francisco
GSPSFO
Greenville
Sat 12/5
5:40 am-12:40 pm
1 stop10h 00m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$197
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from South Carolina with our price prediction graph.
CHS-SFO
GSP-SFO
MYR-SFO
CAE-SFO
HHH-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to San Francisco
USSC-SFO
CHS-SFO
GSP-SFO
MYR-SFO
CAE-SFO
What is the cheapest month to book a flight from South Carolina to San Francisco?
Currently, January is the cheapest month in which you can book a flight from South Carolina to San Francisco (average of $422). Flying from South Carolina to San Francisco in June is currently the most expensive (average of $547). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SC to SFO?
Find hourly flight availability from South Carolina to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2026.
When flying from South Carolina to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Weekly flight availability from South Carolina to San Francisco
Explore weekly flight availability from South Carolina to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 10, 2026.
The most flights from USSC to SFO are scheduled on a Friday (3 on average). You will have fewer flight options on Monday, which is when the least amount of flights are scheduled (1 on average).
How much does it cost to fly round-trip from South Carolina to San Francisco?
Airfare is below average for this route at the moment.
South Carolina to San Francisco flights typically cost between $236 and $610 in December.The cheapest round-trip price found within the last 5 days was $169 on Breeze Airways (Dec 7-Dec 9).
How far ahead should I book a flight from South Carolina to San Francisco?
Booking 39 days in advance of your planned departure date is, on average, the best time to get cheap flights from South Carolina to San Francisco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
San Carlos
Sunnyvale
Turlock
Morgan Hill
San Ramon
Milpitas
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for South Carolina to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Francisco by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to San Francisco by cabin class
Find flights from South Carolina to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and San Francisco flights
Browse other South Carolina and San Francisco flight options. Last updated on November 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.
South Carolina to San Francisco flights
Consider these flights traveling from South Carolina to San Francisco.
Top 5 airlines flying from South Carolina to San Francisco
Discover the top 5 airlines that operate flights from South Carolina to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$213 | Average$527 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$218 | Average$307 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$256 | Average$491 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$268 | Average$479 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$327 | Average$523 | FlexibilityNo cancel fee | On-time63% |