$54+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Mar 5 — Mar 121
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Diego to South Carolina
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.
This Travelocity deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:45 am
SAN
- CLT
1 stop12h 19m
Frontier
Thu 4/164:31 pm
CLT
- SAN
1 stop10h 40m
Frontier
Deal found 2/2![Frontier logo]()
$200
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:59 am
SAN
- CLT
1 stop27h 58m
Frontier
Mon 2/235:13 pm
CLT
- SAN
1 stop9h 55m
Frontier
Deal found 2/3![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Thu 4/162:28 pm
CLT
- SAN
2 stops30h 12m
Frontier
Deal found 2/2![Frontier logo]()
$214
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Mon 3/97:43 pm
CLT
- SAN
1 stop7h 25m
Frontier
Deal found 2/3![Frontier logo]()
$218
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Sun 3/15:03 pm
CLT
- SAN
1 stop10h 05m
Frontier
Deal found 2/3![Frontier logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/79:18 pm
SAN
- CLT
1 stop17h 30m
Frontier
Sat 3/147:43 pm
CLT
- SAN
1 stop31h 25m
Frontier
Deal found 2/3![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/227:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Fri 4/242:28 pm
CLT
- SAN
2 stops32h 36m
Frontier
Deal found 2/3![Frontier logo]()
$230
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Fri 5/810:39 pm
CLT
- SAN
2 stops36h 55m
Frontier
Deal found 2/2![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:45 am
SAN
- CLT
2 stops24h 37m
Frontier
Thu 3/55:13 pm
CLT
- SAN
1 stop17h 52m
Frontier
Deal found 2/2![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Fri 5/19:26 pm
CLT
- SAN
2 stops19h 59m
Frontier
Deal found 2/2![Frontier logo]()
$245
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:44 pm
SAN
- CHS
1 stop9h 41m
JetBlue
Thu 3/510:20 am
CHS
- SAN
1 stop12h 08m
JetBlue
Deal found 2/2![JetBlue logo]()
$269
This Priceline deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:15 pm
SAN
- SAV
1 stop9h 37m
JetBlue
Tue 4/2810:42 am
SAV
- SAN
1 stop12h 22m
JetBlue
Deal found 2/1![JetBlue logo]()
$273
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 3, 2026.
This Travelocity deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2210:00 am
SAN
- CLT
1 stop29h 54m
Frontier
Fri 4/247:49 pm
CLT
- SAN
1 stop27h 15m
Frontier
Deal found 2/3![Frontier logo]()
$235
This Priceline deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:15 pm
SAN
- SAV
1 stop9h 37m
JetBlue
Tue 4/2810:42 am
SAV
- SAN
1 stop12h 22m
JetBlue
Deal found 2/1![JetBlue logo]()
$273
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:54 am
SAN
- CHS
1 stop7h 37m
United Airlines
Tue 5/191:06 pm
CHS
- SAN
1 stop8h 35m
United Airlines
Deal found 2/2![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:45 pm
SAN
- CHS
1 stop7h 58m
Delta
Sun 5/105:15 am
CHS
- SAN
1 stop9h 09m
Delta
Deal found 2/1![Delta logo]()
$320
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:30 am
SAN
- CHS
1 stop8h 50m
Southwest
Mon 5/116:00 am
CHS
- SAN
2 stops8h 50m
Southwest
Deal found 2/1![Southwest logo]()
$348
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/187:42 pm
SAN
- MYR
2 stops9h 58m
American Airlines
Sun 2/223:17 pm
MYR
- SAN
1 stop8h 50m
American Airlines
Deal found 2/2![American Airlines logo]()
$364
This Travelocity deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Fri 5/17:49 pm
CLT
- SAN
1 stop27h 15m
Frontier
Deal found 2/2![Frontier logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Fri 5/84:31 pm
CLT
- SAN
1 stop10h 40m
Frontier
Deal found 2/2![Frontier logo]()
$265
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:16 pm
SAN
- CHS
1 stop6h 42m
United Airlines
Sat 3/78:10 am
CHS
- SAN
2 stops12h 16m
United Airlines
Deal found 2/2![United Airlines logo]()
$314
This Cheapflightsfares deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/69:10 pm
SAN
- CHS
1 stop10h 47m
JetBlue
Sat 3/1412:35 pm
CHS
- SAN
1 stop10h 17m
JetBlue
Deal found 2/2![JetBlue logo]()
$315
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:02 am
SAN
- SAV
1 stop6h 41m
Delta
Mon 4/136:47 pm
SAV
- SAN
1 stop7h 38m
Delta
Deal found 2/2![Delta logo]()
$323
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:45 am
SAN
- CHS
2 stops10h 15m
Southwest
Mon 5/113:50 pm
CHS
- SAN
1 stop9h 25m
Southwest
Deal found 2/2![Southwest logo]()
$348
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:01 am
SAN
- CHS
2 stops9h 58m
United Airlines
Sat 4/256:00 am
CHS
- SAN
1 stop8h 16m
United Airlines
Deal found 2/1![United Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:25 am
SAN
- CLT
1 stop9h 23m
Frontier
Thu 3/127:43 pm
CLT
- SAN
1 stop15h 22m
Frontier
Deal found 2/2![Frontier logo]()
$296
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:00 pm
SAN
- CHS
1 stop10h 18m
Delta
Mon 3/95:51 pm
CHS
- SAN
1 stop9h 20m
Delta
Deal found 2/1![Delta logo]()
$340
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:57 pm
SAN
- GSP
1 stop8h 48m
American Airlines
Sat 2/287:02 am
GSP
- SAN
1 stop9h 36m
American Airlines
Deal found 2/2![American Airlines logo]()
$377
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:15 am
SAN
- SAV
1 stop9h 07m
United Airlines
Fri 4/174:59 pm
SAV
- SAN
1 stop9h 00m
United Airlines
Deal found 1/31![United Airlines logo]()
$318
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/79:30 pm
SAN
- CHS
1 stop9h 10m
Delta
Sun 5/105:15 am
CHS
- SAN
1 stop7h 28m
Delta
Deal found 2/1![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:09 pm
SAN
- SAV
1 stop8h 48m
American Airlines
Sun 3/15:00 am
SAV
- SAN
1 stop9h 17m
American Airlines
Deal found 2/1![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:30 am
SAN
- SAV
2 stops8h 55m
Southwest
Tue 4/286:40 am
SAV
- SAN
2 stops9h 15m
Southwest
Deal found 2/2![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:16 pm
SAN
- SAV
1 stop6h 39m
United Airlines
Tue 3/1010:00 am
SAV
- SAN
2 stops13h 19m
United Airlines
Deal found 2/1![United Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/89:30 pm
SAN
- CHS
1 stop9h 10m
Delta
Sun 5/105:15 am
CHS
- SAN
1 stop9h 09m
Delta
Deal found 2/3![Delta logo]()
$343
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:45 pm
SAN
- CLT
1 stop9h 00m
American Airlines
Sat 3/78:55 am
CLT
- SAN
Nonstop5h 22m
American Airlines
Deal found 2/1![American Airlines logo]()
$383
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:25 pm
SAN
- MYR
2 stops13h 20m
Southwest
Sat 4/181:00 pm
MYR
- SAN
1 stop7h 55m
Southwest
Deal found 2/2![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:15 pm
SAN
- CHS
1 stop8h 49m
United Airlines
Sat 3/712:10 pm
CHS
- SAN
2 stops10h 38m
United Airlines
Deal found 2/1![United Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/97:11 pm
SAN
- HHH
2 stops13h 42m
American Airlines
Tue 3/1712:23 pm
HHH
- SAN
1 stop9h 04m
American Airlines
Deal found 2/1![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1710:20 pm
SAN
- MYR
1 stop8h 25m
Delta
Sat 2/216:00 am
MYR
- SAN
1 stop7h 09m
Delta
Deal found 2/1![Delta logo]()
$359
This Southwest deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/99:40 pm
SAN
- MYR
1 stop9h 25m
Southwest
Mon 4/133:45 pm
MYR
- SAN
2 stops10h 20m
Southwest
Deal found 2/1![Southwest logo]()
$398
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:45 pm
SAN
- HHH
1 stop9h 47m
American Airlines
Sat 5/25:04 pm
HHH
- SAN
2 stops9h 52m
American Airlines
Deal found 2/2![American Airlines logo]()
$388
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:59 am
SAN
- CAE
2 stops9h 45m
United Airlines
Wed 3/42:39 pm
CAE
- SAN
1 stop9h 07m
United Airlines
Deal found 2/2![United Airlines logo]()
$364
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated February 3, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated February 3, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/139:45 am
SAN
- CLT
1 stop8h 35m
Frontier
Sat 2/2110:16 am
CLT
- SAN
2 stops16h 52m
Frontier
Deal found 2/2![Frontier logo]()
$277
This Frontier deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Mon 2/235:13 pm
CLT
- SAN
1 stop9h 55m
Frontier
Deal found 2/2![Frontier logo]()
$254
This Priceline deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/166:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Thu 2/195:13 pm
CLT
- SAN
1 stop9h 55m
Frontier
Deal found 2/2![Frontier logo]()
$270
This CheapOair deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:59 am
SAN
- CLT
1 stop27h 58m
Frontier
Mon 2/235:13 pm
CLT
- SAN
1 stop9h 55m
Frontier
Deal found 2/3![Frontier logo]()
$211
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Sun 3/15:03 pm
CLT
- SAN
1 stop10h 05m
Frontier
Deal found 2/3![Frontier logo]()
$219
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/28:44 pm
SAN
- CHS
1 stop9h 41m
JetBlue
Thu 3/510:20 am
CHS
- SAN
1 stop12h 08m
JetBlue
Deal found 2/2![JetBlue logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:45 am
SAN
- CLT
2 stops24h 37m
Frontier
Thu 3/55:13 pm
CLT
- SAN
1 stop17h 52m
Frontier
Deal found 2/2![Frontier logo]()
$238
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Mon 3/97:43 pm
CLT
- SAN
1 stop7h 25m
Frontier
Deal found 2/3![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/79:18 pm
SAN
- CLT
1 stop17h 30m
Frontier
Sat 3/147:43 pm
CLT
- SAN
1 stop31h 25m
Frontier
Deal found 2/3![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:25 am
SAN
- CLT
1 stop9h 23m
Multiple Airlines
Thu 3/121:20 pm
CLT
- SAN
2 stops14h 11m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$280
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:45 am
SAN
- CHS
1 stop9h 25m
United Airlines
Tue 3/172:48 pm
CHS
- SAN
1 stop8h 57m
United Airlines
Deal found 2/1![United Airlines logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/279:58 pm
SAN
- CLT
2 stops17h 50m
Frontier
Sun 4/57:49 pm
CLT
- SAN
1 stop31h 13m
Frontier
Deal found 2/2![Frontier logo]()
$272
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated February 3, 2026.
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/76:25 am
SAN
- CLT
1 stop9h 03m
Frontier
Deal found 2/2![Frontier logo]()
$54
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:25 am
SAN
- CLT
1 stop9h 23m
Frontier
Deal found 2/2![Frontier logo]()
$80
This Priceline deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/29:50 am
SAN
- CLT
1 stop8h 57m
Frontier
Deal found 2/3![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:45 am
SAN
- CLT
1 stop28h 33m
Frontier
Deal found 2/3![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:15 am
SAN
- CLT
1 stop8h 39m
Frontier
Deal found 2/3![Frontier logo]()
$90
This WAYA deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure WAYA is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:25 am
SAN
- CLT
1 stop6h 53m
Frontier
Deal found 2/3![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2812:23 pm
SAN
- CLT
2 stops17h 20m
Frontier
Deal found 2/3![Frontier logo]()
$100
This Trip.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:25 am
SAN
- CLT
1 stop9h 23m
Frontier
Deal found 2/2![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:11 am
SAN
- CLT
3 stops37h 45m
Multiple Airlines
Deal found 2/3![Multiple Airlines logo]()
$103
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:45 am
SAN
- CLT
1 stop12h 19m
Frontier
Deal found 2/2![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/224:12 pm
SAN
- CHS
2 stops22h 28m
Multiple Airlines
Deal found 2/2![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/37:11 am
SAN
- CLT
2 stops27h 40m
Frontier
Deal found 2/3![Frontier logo]()
$107
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated February 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $200 (Travelocity) |
One-way from | $54 (Trip.com) |
Popular in | December |
Cheapest in | October |
Average price | $481 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
San Diego
Fly to
South Carolina
Route
Depart
Return
Price
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Wed 4/22
10:00 am-6:54 pm
1 stop29h 54m
Charlotte Douglas
Fri 4/24
7:49 pm-8:04 pm
1 stop27h 15m
$235
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Tue 4/28
7:15 am-6:54 pm
1 stop8h 39m
Charlotte Douglas
Fri 5/1
7:49 pm-8:04 pm
1 stop27h 15m
$255
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Tue 5/5
7:15 am-6:54 pm
1 stop8h 39m
Charlotte Douglas
Fri 5/8
4:31 pm-12:11 am
1 stop10h 40m
$265
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Fri 4/24
9:15 pm-9:52 am
1 stop9h 37m
Savannah/Hilton Head
Tue 4/28
10:42 am-8:04 pm
1 stop12h 22m
$273
San DiegoCharlotte
SAN - CLT
SANCLT
San Diego
Mon 3/9
6:25 am-6:48 pm
1 stop9h 23m
Charlotte Douglas
Thu 3/12
7:43 pm-8:05 am
1 stop15h 22m
$296
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Sat 5/16
8:54 am-7:31 pm
1 stop7h 37m
Charleston
Tue 5/19
1:06 pm-6:41 pm
1 stop8h 35m
$307
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Tue 3/3
12:16 pm-9:58 pm
1 stop6h 42m
Charleston
Sat 3/7
8:10 am-5:26 pm
2 stops12h 16m
$314
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Fri 3/6
9:10 pm-10:57 am
1 stop10h 47m
Charleston
Sat 3/14
12:35 pm-7:52 pm
1 stop10h 17m
$315
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Wed 4/22
11:01 am-11:59 pm
2 stops9h 58m
Charleston
Sat 4/25
6:00 am-11:16 am
1 stop8h 16m
$317
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Fri 4/10
6:15 am-6:22 pm
1 stop9h 07m
Savannah/Hilton Head
Fri 4/17
4:59 pm-10:59 pm
1 stop9h 00m
$318
Showing 1-10 of 60 results
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-CLT
SAN-CHS
SAN-SAV
SAN-MYR
SAN-GSP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-CLT
SAN-CHS
SAN-SAV
SAN-MYR
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $149). Flying from San Diego to South Carolina in December is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SAN to SC?
Find hourly flight availability from San Diego to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 3, 2026.
It’s optimal to fly from San Diego to South Carolina at noon. By choosing this option you can save up to 74% on the cost of your flight, compared to a flight in the evening.
What is the cheapest day to fly from San Diego to South Carolina?
Use this chart to determine the cheapest time to fly round-trip from San Diego to South Carolina. Price data was last updated on March 30, 2025.
Travelers seeking maximum savings on their San Diego to South Carolina flight should consider departing on Thursday evenings when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated February 3, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Boarding
8.1
Crew
8.6
Overall
8.0
Comfort
8.0
Food
7.0
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentWilliam Drew,Nov 2025
SJC - HNL
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on February 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$126 | Average$252 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$175 | Average$435 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$199 | Average$499 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$507 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$344 | Average$477 | FlexibilityNo cancel fee | On-time63% |