$129+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Aug 12 — Aug 191
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 13, 2026.
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 am
SAN
- CHS
1 stop7h 45m
Southwest
Sat 8/291:20 pm
CHS
- SAN
1 stop8h 05m
Southwest
Deal found 7/9![Southwest logo]()
$209
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:30 am
SAN
- CHS
1 stop7h 25m
Southwest
Sat 10/246:15 am
CHS
- SAN
2 stops9h 50m
Southwest
Deal found 7/8![Southwest logo]()
$215
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:25 am
SAN
- CHS
2 stops9h 20m
Southwest
Tue 8/257:35 am
CHS
- SAN
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$220
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:25 pm
SAN
- CHS
1 stop6h 50m
Southwest
Wed 10/71:55 pm
CHS
- SAN
1 stop10h 30m
Southwest
Deal found 7/9![Southwest logo]()
$255
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:45 pm
SAN
- GSP
1 stop9h 03m
United Airlines
Sat 8/154:33 pm
GSP
- SAN
1 stop7h 01m
United Airlines
Deal found 7/9![United Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:40 pm
SAN
- CHS
1 stop9h 50m
Southwest
Sat 8/221:20 pm
CHS
- SAN
1 stop8h 05m
Southwest
Deal found 7/8![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:13 am
SAN
- CHS
1 stop8h 58m
United Airlines
Thu 9/102:54 pm
CHS
- SAN
1 stop8h 35m
United Airlines
Deal found 7/10![United Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:40 pm
SAN
- GSP
1 stop7h 56m
United Airlines
Tue 8/252:18 pm
GSP
- SAN
2 stops9h 16m
United Airlines
Deal found 7/9![United Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
SAN
- CHS
1 stop11h 40m
Southwest
Mon 8/2411:30 am
CHS
- SAN
2 stops9h 35m
Southwest
Deal found 7/10![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1010:16 am
SAN
- SAV
1 stop8h 34m
United Airlines
Sat 11/144:16 pm
SAV
- SAN
1 stop9h 14m
United Airlines
Deal found 7/8![United Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:58 am
SAN
- CHS
1 stop7h 17m
United Airlines
Tue 8/112:54 pm
CHS
- SAN
2 stops10h 16m
United Airlines
Deal found 7/10![United Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:40 pm
SAN
- GSP
1 stop10h 50m
Southwest
Mon 8/244:40 pm
GSP
- SAN
1 stop9h 05m
Southwest
Deal found 7/8![Southwest logo]()
$286
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 13, 2026.
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:20 am
SAN
- CHS
1 stop9h 00m
Southwest
Sat 8/224:35 pm
CHS
- SAN
1 stop6h 20m
Southwest
Deal found 7/8![Southwest logo]()
$209
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:32 pm
SAN
- GSP
1 stop7h 27m
Delta
Wed 8/125:46 am
GSP
- SAN
1 stop6h 40m
Delta
Deal found 7/8![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2610:13 am
SAN
- SAV
1 stop8h 46m
United Airlines
Sat 8/2912:59 pm
SAV
- SAN
2 stops9h 56m
United Airlines
Deal found 7/8![United Airlines logo]()
$302
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/510:20 pm
SAN
- SAV
1 stop8h 39m
American Airlines
Wed 8/197:00 am
SAV
- SAN
1 stop7h 57m
American Airlines
Deal found 7/12![American Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:40 pm
SAN
- CHS
1 stop9h 50m
Southwest
Sat 8/221:20 pm
CHS
- SAN
1 stop8h 05m
Southwest
Deal found 7/8![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
SAN
- CHS
1 stop11h 40m
Southwest
Mon 8/248:40 am
CHS
- SAN
2 stops12h 30m
Southwest
Deal found 7/11![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:20 pm
SAN
- GSP
1 stop9h 04m
Delta
Thu 10/17:10 am
GSP
- SAN
1 stop10h 00m
Delta
Deal found 7/10![Delta logo]()
$297
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:52 pm
SAN
- CHS
1 stop8h 05m
Delta
Mon 9/214:10 pm
CHS
- SAN
1 stop7h 50m
Delta
Deal found 7/10![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:35 am
SAN
- CHS
1 stop10h 55m
Southwest
Mon 9/217:15 pm
CHS
- SAN
1 stop7h 10m
Southwest
Deal found 7/9![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:45 pm
SAN
- GSP
2 stops9h 52m
United Airlines
Sat 8/155:43 pm
GSP
- SAN
1 stop7h 27m
United Airlines
Deal found 7/9![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1812:06 pm
SAN
- AGS
1 stop8h 35m
American Airlines
Tue 9/16:50 am
AGS
- SAN
1 stop8h 07m
American Airlines
Deal found 7/9![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/222:00 pm
SAN
- SAV
1 stop7h 21m
Delta
Sat 8/293:25 pm
SAV
- SAN
1 stop7h 10m
Delta
Deal found 7/9![Delta logo]()
$297
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2612:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Sat 8/294:58 pm
CHS
- SAN
1 stop8h 12m
United Airlines
Deal found 7/10![United Airlines logo]()
$341
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:15 am
SAN
- CHS
1 stop10h 25m
Southwest
Wed 10/287:15 am
CHS
- SAN
1 stop8h 55m
Southwest
Deal found 7/11![Southwest logo]()
$289
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:30 am
SAN
- GSP
1 stop8h 50m
Southwest
Mon 8/246:55 pm
GSP
- SAN
1 stop7h 30m
Southwest
Deal found 7/10![Southwest logo]()
$296
This Delta deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:15 am
SAN
- GSP
1 stop8h 57m
Delta
Mon 11/26:45 am
GSP
- SAN
1 stop8h 55m
Delta
Deal found 7/12![Delta logo]()
$333
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:45 pm
SAN
- CAE
1 stop9h 02m
United Airlines
Sat 11/75:40 pm
CAE
- SAN
1 stop7h 48m
United Airlines
Deal found 7/9![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:38 pm
SAN
- AGS
1 stop7h 03m
American Airlines
Sat 8/158:25 am
AGS
- SAN
1 stop7h 23m
American Airlines
Deal found 7/11![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/310:30 pm
SAN
- CAE
1 stop9h 09m
United Airlines
Tue 8/112:56 pm
CAE
- SAN
1 stop8h 33m
United Airlines
Deal found 7/12![United Airlines logo]()
$369
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:25 pm
SAN
- GSP
1 stop8h 00m
Delta
Wed 9/235:45 am
GSP
- SAN
1 stop7h 01m
Delta
Deal found 7/10![Delta logo]()
$338
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:20 am
SAN
- MYR
2 stops10h 00m
Southwest
Tue 9/12:25 pm
MYR
- SAN
2 stops10h 35m
Southwest
Deal found 7/11![Southwest logo]()
$310
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1110:27 pm
SAN
- AGS
1 stop8h 20m
American Airlines
Sat 9/193:59 pm
AGS
- SAN
1 stop7h 02m
American Airlines
Deal found 7/10![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:40 pm
SAN
- CAE
1 stop8h 03m
United Airlines
Tue 8/182:56 pm
CAE
- SAN
2 stops10h 14m
United Airlines
Deal found 7/12![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:30 am
SAN
- SAV
2 stops9h 15m
Southwest
Sat 10/104:45 pm
SAV
- SAN
1 stop7h 40m
Southwest
Deal found 7/11![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:25 pm
SAN
- AGS
1 stop8h 01m
Delta
Sat 8/156:48 pm
AGS
- SAN
1 stop7h 12m
Delta
Deal found 7/8![Delta logo]()
$349
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/299:25 pm
SAN
- AGS
1 stop8h 04m
American Airlines
Tue 8/44:00 pm
AGS
- SAN
1 stop9h 37m
American Airlines
Deal found 7/11![American Airlines logo]()
$443
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:25 pm
SAN
- CAE
1 stop9h 03m
United Airlines
Thu 8/132:56 pm
CAE
- SAN
1 stop8h 33m
United Airlines
Deal found 7/8![United Airlines logo]()
$381
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:00 am
SAN
- AGS
1 stop8h 47m
Delta
Wed 9/96:00 am
AGS
- SAN
1 stop6h 46m
Delta
Deal found 7/8![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:35 am
SAN
- SAV
2 stops8h 00m
Southwest
Wed 8/1910:50 am
SAV
- SAN
2 stops9h 05m
Southwest
Deal found 7/12![Southwest logo]()
$333
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:15 pm
SAN
- AGS
2 stops10h 14m
American Airlines
Sat 8/14:00 pm
AGS
- SAN
2 stops8h 34m
American Airlines
Deal found 7/11![American Airlines logo]()
$464
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated July 13, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated July 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:59 pm
SAN
- CHS
1 stop9h 12m
United Airlines
Tue 8/116:30 am
CHS
- SAN
1 stop7h 45m
United Airlines
Deal found 7/10![United Airlines logo]()
$263
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:45 pm
SAN
- GSP
1 stop9h 03m
United Airlines
Sat 8/154:33 pm
GSP
- SAN
1 stop7h 01m
United Airlines
Deal found 7/9![United Airlines logo]()
$261
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Thu 8/202:54 pm
CHS
- SAN
1 stop8h 35m
United Airlines
Deal found 7/11![United Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:40 pm
SAN
- CHS
1 stop9h 50m
Southwest
Sat 8/221:20 pm
CHS
- SAN
1 stop8h 05m
Southwest
Deal found 7/8![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1710:40 pm
SAN
- GSP
1 stop7h 56m
United Airlines
Tue 8/252:18 pm
GSP
- SAN
2 stops9h 16m
United Airlines
Deal found 7/9![United Airlines logo]()
$266
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:25 am
SAN
- CHS
2 stops9h 20m
Southwest
Tue 8/257:35 am
CHS
- SAN
2 stops8h 25m
Southwest
Deal found 7/10![Southwest logo]()
$220
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:05 am
SAN
- CHS
2 stops9h 40m
Southwest
Sat 8/224:35 pm
CHS
- SAN
1 stop6h 20m
Southwest
Deal found 7/8![Southwest logo]()
$215
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
SAN
- CHS
1 stop11h 40m
Southwest
Mon 8/2411:30 am
CHS
- SAN
2 stops9h 35m
Southwest
Deal found 7/10![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:40 pm
SAN
- GSP
1 stop10h 50m
Southwest
Mon 8/244:40 pm
GSP
- SAN
1 stop9h 05m
Southwest
Deal found 7/8![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:30 am
SAN
- GSP
1 stop8h 50m
Southwest
Mon 8/246:55 pm
GSP
- SAN
1 stop7h 30m
Southwest
Deal found 7/10![Southwest logo]()
$296
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:20 am
SAN
- CHS
2 stops10h 00m
Southwest
Sat 8/2911:00 am
CHS
- SAN
2 stops8h 15m
Southwest
Deal found 7/9![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:40 am
SAN
- CHS
1 stop7h 45m
Southwest
Sat 8/291:20 pm
CHS
- SAN
1 stop8h 05m
Southwest
Deal found 7/9![Southwest logo]()
$209
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:03 pm
SAN
- CLT
2 stops37h 48m
Frontier
Deal found 7/11![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:03 pm
SAN
- CLT
2 stops37h 48m
Frontier
Deal found 7/11![Frontier logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/53:03 pm
SAN
- MYR
2 stops16h 02m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$131
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:30 pm
SAN
- GSP
1 stop8h 05m
United Airlines
Deal found 7/9![United Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:40 pm
SAN
- CHS
1 stop9h 15m
Southwest
Deal found 7/8![Southwest logo]()
$132
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/298:00 am
SAN
- SAV
1 stop7h 06m
United Airlines
Deal found 7/8![United Airlines logo]()
$134
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am
SAN
- GSP
1 stop10h 45m
Southwest
Deal found 7/9![Southwest logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/59:19 am
SAN
- CLT
1 stop22h 56m
Frontier
Deal found 7/9![Frontier logo]()
$139
This United Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Deal found 7/11![United Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/119:19 am
SAN
- CLT
1 stop22h 56m
Frontier
Deal found 7/11![Frontier logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:35 am
SAN
- CLT
1 stop25h 41m
Frontier
Deal found 7/9![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:25 am
SAN
- CLT
2 stops33h 17m
Frontier
Deal found 7/9![Frontier logo]()
$143
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated July 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (Southwest) |
One-way from | $129 (Kiwi.com) |
Popular in | April |
Cheapest in | October |
Average price | $492 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Wed 8/19
6:20 am-6:20 pm
1 stop9h 00m
Charleston
Sat 8/22
4:35 pm-7:55 pm
1 stop6h 20m
$209
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Sat 8/15
10:40 pm-11:30 am
1 stop9h 50m
Charleston
Sat 8/22
1:20 pm-6:25 pm
1 stop8h 05m
$262
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Thu 8/20
6:45 am-9:25 pm
1 stop11h 40m
Charleston
Mon 8/24
8:40 am-6:10 pm
2 stops12h 30m
$266
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Fri 9/18
6:35 am-8:30 pm
1 stop10h 55m
Charleston
Mon 9/21
7:15 pm-11:25 pm
1 stop7h 10m
$279
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Sat 10/24
6:15 am-7:40 pm
1 stop10h 25m
Charleston
Wed 10/28
7:15 am-1:10 pm
1 stop8h 55m
$289
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Fri 8/21
6:30 am-6:20 pm
1 stop8h 50m
Greenville
Mon 8/24
6:55 pm-11:25 pm
1 stop7h 30m
$296
Quickest round-trip
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 8/5
12:32 pm-10:59 pm
1 stop7h 27m
Greenville
Wed 8/12
5:46 am-9:26 am
1 stop6h 40m
$297
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Thu 9/24
10:20 pm-10:24 am
1 stop9h 04m
Greenville
Thu 10/1
7:10 am-2:10 pm
1 stop10h 00m
$297
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Fri 9/18
12:52 pm-11:57 pm
1 stop8h 05m
Charleston
Mon 9/21
4:10 pm-9:00 pm
1 stop7h 50m
$297
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Sat 8/22
2:00 pm-12:21 am
1 stop7h 21m
Savannah/Hilton Head
Sat 8/29
3:25 pm-7:35 pm
1 stop7h 10m
$297
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-GSP
SAN-CHS
SAN-MYR
SAN-SAV
SAN-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-GSP
SAN-CHS
SAN-MYR
SAN-SAV
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $134). Flying from San Diego to South Carolina in June is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to South Carolina?
How far ahead should I book a flight from San Diego to South Carolina?
The price you pay for your flight from San Diego to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 13, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Comfort
8.0
Overall
8.0
Boarding
8.1
Crew
8.6
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South Carolina by cabin class
Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on July 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$134 | Average$274 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$529 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$479 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$510 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$363 | Average$517 | FlexibilityNo cancel fee | On-time63% |