$130+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/16. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Jul 16 — Jul 231
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 16, 2026.
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:20 am
SAN
- CHS
1 stop6h 19m
Delta
Wed 10/2812:15 pm
CHS
- SAN
1 stop9h 27m
Delta
Deal found 6/13![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:20 am
SAN
- CHS
1 stop9h 25m
Southwest
Tue 8/116:45 am
CHS
- SAN
2 stops9h 45m
Southwest
Deal found 6/12![Southwest logo]()
$320
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:25 pm
SAN
- CHS
1 stop9h 42m
American Airlines
Wed 7/157:53 pm
CHS
- SAN
1 stop7h 06m
American Airlines
Deal found 6/13![American Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Sat 9/511:40 am
CHS
- SAN
1 stop9h 50m
United Airlines
Deal found 6/11![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:00 pm
SAN
- CHS
2 stops10h 05m
Southwest
Wed 9/161:15 pm
CHS
- SAN
1 stop6h 35m
Southwest
Deal found 6/15![Southwest logo]()
$338
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:30 am
SAN
- CHS
1 stop9h 00m
Southwest
Tue 11/247:55 pm
CHS
- SAN
1 stop7h 00m
Southwest
Deal found 6/12![Southwest logo]()
$342
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:18 pm
SAN
- CHS
1 stop7h 08m
Delta
Mon 8/106:45 pm
CHS
- SAN
1 stop7h 15m
Delta
Deal found 6/16![Delta logo]()
$343
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:30 pm
SAN
- GSP
1 stop9h 07m
United Airlines
Wed 8/54:15 pm
GSP
- SAN
1 stop7h 31m
United Airlines
Deal found 6/12![United Airlines logo]()
$346
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Mon 8/176:30 am
CHS
- SAN
1 stop7h 45m
United Airlines
Deal found 6/16![United Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/269:37 am
SAN
- CLT
1 stop29h 42m
Frontier
Tue 9/17:14 pm
CLT
- SAN
1 stop16h 28m
Frontier
Deal found 6/13![Frontier logo]()
$347
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:40 pm
SAN
- CHS
1 stop11h 30m
Southwest
Wed 7/226:50 pm
CHS
- SAN
1 stop7h 40m
Southwest
Deal found 6/14![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:05 am
SAN
- CHS
1 stop8h 10m
Southwest
Mon 8/107:15 pm
CHS
- SAN
1 stop7h 10m
Southwest
Deal found 6/16![Southwest logo]()
$350
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 16, 2026.
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:40 pm
SAN
- CHS
1 stop11h 30m
Southwest
Wed 7/226:50 pm
CHS
- SAN
1 stop7h 40m
Southwest
Deal found 6/14![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/121:38 pm
SAN
- AGS
1 stop7h 03m
American Airlines
Sat 8/153:59 pm
AGS
- SAN
1 stop8h 04m
American Airlines
Deal found 6/16![American Airlines logo]()
$350
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:18 pm
SAN
- GSP
1 stop6h 36m
Delta
Thu 7/235:16 pm
GSP
- SAN
1 stop8h 41m
Delta
Deal found 6/16![Delta logo]()
$351
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:15 am
SAN
- GSP
1 stop6h 44m
United Airlines
Thu 8/64:15 pm
GSP
- SAN
1 stop9h 10m
United Airlines
Deal found 6/12![United Airlines logo]()
$351
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:30 pm
SAN
- GSP
1 stop8h 43m
Delta
Mon 8/31:28 pm
GSP
- SAN
1 stop6h 36m
Delta
Deal found 6/15![Delta logo]()
$351
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:40 pm
SAN
- GSP
1 stop6h 25m
Southwest
Thu 7/231:55 pm
GSP
- SAN
1 stop12h 30m
Southwest
Deal found 6/13![Southwest logo]()
$356
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:40 am
SAN
- CHS
1 stop7h 38m
United Airlines
Thu 7/94:16 pm
CHS
- SAN
1 stop9h 09m
United Airlines
Deal found 6/12![United Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:40 pm
SAN
- CHS
1 stop9h 45m
Southwest
Mon 8/106:35 am
CHS
- SAN
2 stops9h 50m
Southwest
Deal found 6/13![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:15 pm
SAN
- SAV
1 stop9h 37m
Delta
Mon 7/275:16 pm
SAV
- SAN
1 stop9h 14m
Delta
Deal found 6/12![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:41 pm
SAN
- HHH
2 stops15h 22m
United Airlines
Mon 8/312:48 pm
HHH
- SAN
1 stop10h 22m
United Airlines
Deal found 6/13![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/279:25 pm
SAN
- AGS
1 stop8h 04m
American Airlines
Wed 7/16:30 am
AGS
- SAN
1 stop6h 39m
American Airlines
Deal found 6/12![American Airlines logo]()
$443
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:15 am
SAN
- SAV
1 stop6h 38m
Delta
Tue 8/2511:22 am
SAV
- SAN
1 stop9h 52m
Delta
Deal found 6/15![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:35 am
SAN
- SAV
2 stops8h 10m
Southwest
Wed 7/226:30 pm
SAV
- SAN
1 stop8h 00m
Southwest
Deal found 6/15![Southwest logo]()
$372
This United Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1312:01 pm
SAN
- CHS
1 stop7h 10m
United Airlines
Sun 8/167:00 am
CHS
- SAN
1 stop9h 17m
United Airlines
Deal found 6/16![United Airlines logo]()
$404
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:30 pm
SAN
- AGS
1 stop8h 05m
Delta
Fri 7/104:11 pm
AGS
- SAN
1 stop8h 05m
Delta
Deal found 6/15![Delta logo]()
$370
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:35 am
SAN
- SAV
1 stop8h 20m
Southwest
Mon 7/275:25 pm
SAV
- SAN
2 stops8h 45m
Southwest
Deal found 6/16![Southwest logo]()
$372
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:20 pm
SAN
- CAE
1 stop8h 14m
American Airlines
Sat 8/153:59 pm
CAE
- SAN
1 stop6h 45m
American Airlines
Deal found 6/14![American Airlines logo]()
$468
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:35 am
SAN
- SAV
2 stops8h 05m
Southwest
Sat 9/191:10 pm
SAV
- SAN
2 stops10h 10m
Southwest
Deal found 6/14![Southwest logo]()
$377
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:30 pm
SAN
- AGS
1 stop8h 03m
Delta
Fri 7/177:23 pm
AGS
- SAN
1 stop6h 34m
Delta
Deal found 6/12![Delta logo]()
$392
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:40 pm
SAN
- SAV
1 stop10h 55m
Southwest
Wed 7/157:50 am
SAV
- SAN
2 stops9h 25m
Southwest
Deal found 6/13![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:30 pm
SAN
- AGS
1 stop9h 03m
Delta
Mon 8/35:14 pm
AGS
- SAN
1 stop6h 44m
Delta
Deal found 6/13![Delta logo]()
$392
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:47 pm
SAN
- FLO
1 stop7h 12m
American Airlines
Sat 9/191:43 pm
FLO
- SAN
1 stop8h 34m
American Airlines
Deal found 6/15![American Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:55 pm
SAN
- CAE
2 stops11h 52m
United Airlines
Sat 8/152:56 pm
CAE
- SAN
1 stop8h 33m
United Airlines
Deal found 6/12![United Airlines logo]()
$486
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:35 am
SAN
- CLT
2 stops8h 35m
Southwest
Tue 8/118:05 am
CLT
- SAN
1 stop7h 10m
Southwest
Deal found 6/13![Southwest logo]()
$384
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:19 pm
SAN
- FLO
1 stop7h 18m
American Airlines
Tue 7/282:35 pm
FLO
- SAN
1 stop7h 15m
American Airlines
Deal found 6/12![American Airlines logo]()
$525
This Delta deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:30 pm
SAN
- SAV
1 stop9h 12m
Delta
Sat 10/245:35 pm
SAV
- SAN
1 stop8h 28m
Delta
Deal found 6/14![Delta logo]()
$403
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:35 am
SAN
- CLT
2 stops8h 15m
Southwest
Wed 8/512:35 pm
CLT
- SAN
1 stop9h 20m
Southwest
Deal found 6/14![Southwest logo]()
$384
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:45 pm
SAN
- MYR
1 stop8h 59m
United Airlines
Sat 9/194:00 pm
MYR
- SAN
1 stop7h 37m
United Airlines
Deal found 6/12![United Airlines logo]()
$523
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/209:30 pm
SAN
- GSP
1 stop8h 43m
Delta
Sat 8/13:06 pm
GSP
- SAN
1 stop7h 29m
Delta
Deal found 6/15![Delta logo]()
$405
This American Airlines deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:28 pm
SAN
- HHH
1 stop9h 49m
American Airlines
Fri 7/244:55 pm
HHH
- SAN
2 stops10h 04m
American Airlines
Deal found 6/16![American Airlines logo]()
$548
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated June 16, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated June 16, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/2610:04 am
SAN
- CLT
1 stop8h 21m
Frontier
Mon 7/1310:04 pm
CLT
- SAN
1 stop14h 01m
Frontier
Deal found 6/11![Frontier logo]()
$355
This Frontier deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:25 am
SAN
- CLT
1 stop12h 00m
Frontier
Wed 7/1510:04 pm
CLT
- SAN
1 stop14h 01m
Frontier
Deal found 6/13![Frontier logo]()
$359
This Expedia deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/49:37 am
SAN
- CLT
1 stop8h 48m
Frontier
Wed 7/810:04 pm
CLT
- SAN
1 stop14h 01m
Frontier
Deal found 6/15![Frontier logo]()
$357
This Frontier deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:35 am
SAN
- CLT
1 stop11h 27m
Frontier
Mon 7/1310:04 pm
CLT
- SAN
1 stop14h 01m
Frontier
Deal found 6/14![Frontier logo]()
$358
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/119:25 pm
SAN
- CHS
1 stop9h 42m
American Airlines
Wed 7/157:53 pm
CHS
- SAN
1 stop7h 06m
American Airlines
Deal found 6/13![American Airlines logo]()
$333
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:40 am
SAN
- CHS
2 stops11h 10m
Southwest
Wed 7/156:50 pm
CHS
- SAN
1 stop7h 40m
Southwest
Deal found 6/14![Southwest logo]()
$355
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/136:30 am
SAN
- CHS
1 stop7h 15m
Southwest
Wed 7/154:50 pm
CHS
- SAN
1 stop9h 10m
Southwest
Deal found 6/12![Southwest logo]()
$351
This Delta deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/152:18 pm
SAN
- CHS
1 stop7h 08m
Delta
Mon 8/106:45 pm
CHS
- SAN
1 stop7h 15m
Delta
Deal found 6/16![Delta logo]()
$343
This Southwest deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:05 am
SAN
- CHS
1 stop8h 10m
Southwest
Mon 8/107:15 pm
CHS
- SAN
1 stop7h 10m
Southwest
Deal found 6/16![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:40 pm
SAN
- GSP
1 stop6h 25m
Southwest
Thu 7/231:55 pm
GSP
- SAN
1 stop12h 30m
Southwest
Deal found 6/13![Southwest logo]()
$356
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2010:40 pm
SAN
- CHS
1 stop11h 30m
Southwest
Wed 7/226:50 pm
CHS
- SAN
1 stop7h 40m
Southwest
Deal found 6/14![Southwest logo]()
$349
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:30 pm
SAN
- GSP
1 stop7h 43m
Delta
Thu 7/305:16 pm
GSP
- SAN
1 stop7h 00m
Delta
Deal found 6/15![Delta logo]()
$351
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 16, 2026.
This Frontier deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:25 am
SAN
- CLT
1 stop9h 21m
Frontier
Deal found 6/16![Frontier logo]()
$130
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1510:10 am
SAN
- CLT
1 stop8h 09m
Frontier
Deal found 6/15![Frontier logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/113:03 pm
SAN
- CLT
2 stops23h 09m
Frontier
Deal found 6/12![Frontier logo]()
$134
This Priceline deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:25 am
SAN
- CLT
1 stop11h 54m
Frontier
Deal found 6/16![Frontier logo]()
$136
This Frontier deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:35 am
SAN
- CLT
1 stop11h 27m
Frontier
Deal found 6/15![Frontier logo]()
$138
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:25 am
SAN
- CLT
1 stop9h 21m
Frontier
Deal found 6/12![Frontier logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:03 pm
SAN
- CLT
2 stops24h 00m
Frontier
Deal found 6/15![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/199:53 pm
SAN
- CLT
2 stops57h 38m
Frontier
Deal found 6/14![Frontier logo]()
$150
This Frontier deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:25 am
SAN
- CLT
1 stop11h 54m
Frontier
Deal found 6/12![Frontier logo]()
$153
This Priceline deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:35 am
SAN
- CLT
1 stop11h 27m
Frontier
Deal found 6/16![Frontier logo]()
$155
This Booking.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:35 am
SAN
- CLT
1 stop11h 27m
Frontier
Deal found 6/12![Frontier logo]()
$156
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/149:45 pm
SAN
- CHS
1 stop9h 26m
United Airlines
Deal found 6/14![United Airlines logo]()
$158
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated June 16, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $315 (American Airlines) |
One-way from | $130 (Frontier) |
Popular in | April |
Cheapest in | October |
Average price | $573 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Mon 7/20
10:40 pm-1:10 pm
1 stop11h 30m
Charleston
Wed 7/22
6:50 pm-11:30 pm
1 stop7h 40m
$349
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Wed 8/12
1:38 pm-11:41 pm
1 stop7h 03m
Augusta Bush Field
Sat 8/15
3:59 pm-9:03 pm
1 stop8h 04m
$350
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 7/15
2:18 pm-11:54 pm
1 stop6h 36m
Greenville
Thu 7/23
5:16 pm-10:57 pm
1 stop8h 41m
$351
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Tue 8/4
6:15 am-3:59 pm
1 stop6h 44m
Greenville
Thu 8/6
4:15 pm-10:25 pm
1 stop9h 10m
$351
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Mon 7/20
9:30 pm-9:13 am
1 stop8h 43m
Greenville
Mon 8/3
1:28 pm-5:04 pm
1 stop6h 36m
$351
San DiegoGreenville
SAN - GSP
SANGSP
San Diego
Wed 7/15
12:40 pm-10:05 pm
1 stop6h 25m
Greenville
Thu 7/23
1:55 pm-11:25 pm
1 stop12h 30m
$356
San DiegoCharleston
SAN - CHS
SANCHS
San Diego
Thu 8/6
10:40 pm-11:25 am
1 stop9h 45m
Charleston
Mon 8/10
6:35 am-1:25 pm
2 stops9h 50m
$367
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Mon 7/20
10:15 pm-10:52 am
1 stop9h 37m
Savannah/Hilton Head
Mon 7/27
5:16 pm-11:30 pm
1 stop9h 14m
$367
San DiegoSavannah
SAN - SAV
SANSAV
San Diego
Thu 8/20
6:15 am-3:53 pm
1 stop6h 38m
Savannah/Hilton Head
Tue 8/25
11:22 am-6:14 pm
1 stop9h 52m
$367
San DiegoAugusta
SAN - AGS
SANAGS
San Diego
Fri 7/3
10:30 pm-9:35 am
1 stop8h 05m
Augusta Bush Field
Fri 7/10
4:11 pm-9:16 pm
1 stop8h 05m
$370
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-CHS
SAN-GSP
SAN-CLT
SAN-AGS
SAN-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-CHS
SAN-GSP
SAN-CLT
SAN-AGS
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $134). Flying from San Diego to South Carolina in June is currently the most expensive (average of $390). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to South Carolina?
How far ahead should I book a flight from San Diego to South Carolina?
The price you pay for your flight from San Diego to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 81 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 16, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Overall
7.9
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to South Carolina by cabin class
Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on June 16, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 16, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$134 | Average$274 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$528 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$296 | Average$480 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$328 | Average$525 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$378 | Average$519 | FlexibilityNo cancel fee | On-time63% |