$129+ Cheap flights from San Diego (SAN) to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/10. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — CHS
Oct 12 — Oct 191
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to South CarolinaExplore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
Explore the most affordable flight options available from San Diego to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:53 pm -
1 stop20h 09m
Sat 10/244:47 pm -
1 stop10h 09m
Deal found 9/12![Frontier logo]()
$202
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:25 am -
1 stop6h 37m
Thu 10/294:47 pm -
1 stop26h 21m
Deal found 9/8![Frontier logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:53 pm -
1 stop20h 03m
Mon 11/164:47 pm -
1 stop10h 10m
Deal found 9/11![Frontier logo]()
$267
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:53 pm -
1 stop20h 03m
Mon 11/24:47 pm -
1 stop26h 11m
Deal found 9/10![Frontier logo]()
$273
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:25 am -
1 stop6h 31m
Mon 11/24:47 pm -
1 stop10h 10m
Deal found 9/9![Frontier logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:53 pm -
1 stop20h 03m
Sun 11/154:51 pm -
1 stop10h 06m
Deal found 9/10![Frontier logo]()
$294
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
1 stop8h 05m
Sat 12/54:55 pm -
1 stop6h 30m
Deal found 9/9![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop7h 19m
Sat 10/105:25 pm -
1 stop7h 21m
Deal found 9/8![American Airlines logo]()
$300
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:25 am -
1 stop6h 37m
Mon 10/264:47 pm -
1 stop26h 11m
Deal found 9/8![Frontier logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:20 am -
2 stops11h 39m
Sat 12/55:15 pm -
1 stop7h 17m
Deal found 9/9![United Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:27 pm -
1 stop8h 10m
Tue 10/65:25 pm -
1 stop9h 13m
Deal found 9/9![American Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:04 pm -
1 stop7h 17m
Sat 10/247:00 am -
1 stop6h 58m
Deal found 9/8![United Airlines logo]()
$320
Best flights from San Diego to South CarolinaDiscover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
Discover carefully curated flight deals from San Diego to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 12, 2026.
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:05 am -
1 stop8h 05m
Sat 12/54:55 pm -
1 stop6h 30m
Deal found 9/9![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:01 pm -
1 stop6h 33m
Mon 12/147:20 am -
1 stop10h 03m
Deal found 9/9![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:10 pm -
1 stop6h 44m
Mon 1/114:00 pm -
1 stop8h 12m
Deal found 9/9![United Airlines logo]()
$373
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/157:00 am -
1 stop10h 42m
Wed 1/205:30 am -
2 stops12h 06m
Deal found 9/10![Delta logo]()
$430
This Alaska Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:45 pm -
1 stop26h 14m
Mon 10/53:53 pm -
1 stop9h 34m
Deal found 9/9![Alaska Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:30 am -
1 stop7h 25m
Sat 10/241:15 pm -
2 stops8h 55m
Deal found 9/8![Southwest logo]()
$330
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/412:05 pm -
1 stop6h 54m
Sat 11/215:37 pm -
1 stop8h 03m
Deal found 9/8![United Airlines logo]()
$382
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:50 pm -
1 stop9h 10m
Wed 10/287:10 pm -
1 stop7h 10m
Deal found 9/8![Southwest logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:30 pm -
1 stop8h 16m
Wed 10/146:15 am -
2 stops10h 29m
Deal found 9/9![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/109:50 pm -
1 stop9h 10m
Sat 10/176:15 am -
2 stops9h 05m
Deal found 9/10![Southwest logo]()
$362
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:25 pm -
1 stop8h 05m
Tue 10/135:40 am -
2 stops12h 24m
Deal found 9/9![Delta logo]()
$447
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:27 pm -
1 stop8h 14m
Tue 10/1310:08 am -
1 stop10h 31m
Deal found 9/8![American Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:40 pm -
1 stop9h 55m
Sat 10/318:05 am -
2 stops13h 00m
Deal found 9/9![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/26:50 am -
1 stop7h 04m
Wed 2/37:00 am -
1 stop9h 47m
Deal found 9/8![United Airlines logo]()
$409
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:25 am -
1 stop7h 09m
Fri 10/236:31 pm -
1 stop7h 53m
Deal found 9/9![Delta logo]()
$464
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:15 am -
1 stop9h 20m
Mon 11/237:10 pm -
1 stop7h 35m
Deal found 9/7![Southwest logo]()
$373
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:27 pm -
1 stop9h 51m
Wed 9/3012:50 pm -
1 stop8h 32m
Deal found 9/10![American Airlines logo]()
$511
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:04 pm -
1 stop7h 17m
Mon 10/53:00 pm -
1 stop8h 29m
Deal found 9/11![United Airlines logo]()
$434
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:30 am -
1 stop9h 40m
Sat 10/174:10 pm -
1 stop8h 20m
Deal found 9/9![Southwest logo]()
$373
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 am -
1 stop8h 36m
Tue 10/2710:42 am -
2 stops9h 35m
Deal found 9/11![United Airlines logo]()
$442
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/87:40 am -
2 stops9h 10m
Mon 1/118:00 am -
1 stop9h 35m
Deal found 9/9![Southwest logo]()
$378
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
2 stops11h 12m
Tue 10/135:25 am -
2 stops12h 39m
Deal found 9/9![Delta logo]()
$568
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/107:41 pm -
2 stops11h 46m
Sat 10/1711:28 am -
2 stops11h 40m
Deal found 9/10![United Airlines logo]()
$445
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:25 pm -
1 stop8h 12m
Mon 10/124:12 pm -
1 stop8h 25m
Deal found 9/7![American Airlines logo]()
$606
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:15 am -
2 stops9h 15m
Fri 10/303:55 pm -
1 stop8h 10m
Deal found 9/8![Southwest logo]()
$392
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:45 pm -
1 stop8h 59m
Tue 10/135:00 pm -
1 stop8h 41m
Deal found 9/8![United Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:08 pm -
1 stop8h 20m
Mon 9/283:59 pm -
1 stop8h 49m
Deal found 9/9![American Airlines logo]()
$611
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/710:40 pm -
1 stop8h 55m
Wed 10/146:55 pm -
1 stop7h 25m
Deal found 9/9![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:00 am -
2 stops12h 59m
Wed 10/1411:27 am -
2 stops11h 41m
Deal found 9/9![United Airlines logo]()
$461
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:30 am -
2 stops9h 30m
Wed 10/1410:35 am -
2 stops9h 40m
Deal found 9/10![Southwest logo]()
$409
Last-minute flights from San Diego to South CarolinaDiscover last-minute flight deals from San Diego to South Carolina. Data last updated September 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to South Carolina. Data last updated September 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/210:27 pm -
1 stop8h 10m
Tue 10/65:25 pm -
1 stop9h 13m
Deal found 9/9![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:15 am -
1 stop7h 19m
Sat 10/105:25 pm -
1 stop7h 21m
Deal found 9/8![American Airlines logo]()
$300
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:45 pm -
1 stop12h 26m
Mon 10/57:54 pm -
1 stop6h 57m
Deal found 9/9![Frontier logo]()
$323
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:30 am -
1 stop7h 25m
Sat 10/248:05 am -
1 stop9h 20m
Deal found 9/7![Southwest logo]()
$325
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:00 am -
2 stops11h 41m
Sat 10/247:00 am -
1 stop6h 58m
Deal found 9/9![United Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:53 pm -
1 stop20h 09m
Sat 10/244:47 pm -
1 stop10h 09m
Deal found 9/12![Frontier logo]()
$202
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:25 am -
1 stop6h 37m
Mon 10/264:47 pm -
1 stop26h 11m
Deal found 9/8![Frontier logo]()
$303
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2112:04 pm -
1 stop7h 17m
Sat 10/247:00 am -
1 stop6h 58m
Deal found 9/8![United Airlines logo]()
$320
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:25 am -
1 stop6h 37m
Thu 10/294:47 pm -
1 stop26h 21m
Deal found 9/8![Frontier logo]()
$258
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:53 pm -
1 stop20h 03m
Mon 11/24:47 pm -
1 stop26h 11m
Deal found 9/10![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:53 pm -
1 stop20h 03m
Wed 11/1112:05 pm -
2 stops25h 06m
Deal found 9/10![Frontier logo]()
$329
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:25 am -
1 stop6h 31m
Mon 11/24:47 pm -
1 stop10h 10m
Deal found 9/9![Frontier logo]()
$293
One-way flights from San Diego to South CarolinaSearch for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
Search for one-way flight options from San Diego to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 12, 2026.
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:25 am -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:32 pm -
2 stops11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$131
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/94:41 pm -
1 stop20h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:34 pm -
2 stops11h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:32 pm -
2 stops11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Frontier logo]()
$143
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:11 am -
1 stop8h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![United Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:53 pm -
1 stop20h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$150
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:53 pm -
1 stop20h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$151
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:32 pm -
2 stops11h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$153
This Frontier deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:25 am -
1 stop9h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Frontier logo]()
$160
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:05 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Southwest logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:56 am -
2 stops32h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$165
Find flight deals from San Diego to South Carolina
Keep the following information in mind while searching for San Diego to South Carolina flight deals. Data was last updated September 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $258 (Expedia) |
One-way from | $129 (Frontier) |
Popular in | November |
Cheapest in | January |
Average price | $504 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
Use the filters below to find and compare flights from San Diego to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Tue 10/6
10:11 am-9:58 pm
1 stop8h 47m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$150
San DiegoGreenville
SAN San Diego - GSP Greenville
SANGSP
San Diego
Tue 10/13
10:40 pm-12:40 pm
1 stop11h 00m
Greenville
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$155
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Sat 12/12
10:30 pm-10:14 am
1 stop8h 44m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$163
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Wed 11/4
10:25 pm-9:25 am
1 stop8h 00m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$163
San DiegoCharleston
SAN San Diego - CHS Charleston
SANCHS
San Diego
Tue 10/6
12:04 pm-10:21 pm
1 stop7h 17m
Charleston
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$174
San DiegoSavannah
SAN San Diego - SAV Savannah/Hilton Head
SANSAV
San Diego
Mon 10/26
9:50 pm-10:15 am
1 stop9h 25m
Savannah/Hilton Head
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$179
San DiegoCharlotte
SAN San Diego - CLT Charlotte Douglas
SANCLT
San Diego
Sat 11/7
7:15 am-7:00 pm
2 stops8h 45m
Charlotte Douglas
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$184
San DiegoMyrtle Beach
SAN San Diego - MYR Myrtle Beach Intl
SANMYR
San Diego
Sat 10/17
10:27 pm-8:37 am
1 stop7h 10m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San DiegoMyrtle Beach
SAN San Diego - MYR Myrtle Beach Intl
SANMYR
San Diego
Sat 10/24
9:20 pm-10:21 am
1 stop10h 01m
Myrtle Beach Intl
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$185
San DiegoSavannah
SAN San Diego - SAV Savannah/Hilton Head
SANSAV
San Diego
Fri 10/9
10:00 pm-10:34 am
1 stop9h 34m
Savannah/Hilton Head
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$195
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from San Diego to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from San Diego with our price prediction graph.
SAN-CLT
SAN-GSP
SAN-CHS
SAN-MYR
SAN-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to South Carolina
SAN-USSC
SAN-CLT
SAN-GSP
SAN-CHS
SAN-MYR
What is the cheapest month to book a flight from San Diego to South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Diego to South Carolina (average of $393). Flying from San Diego to South Carolina in March is currently the most expensive (average of $545). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to South Carolina?
Airfare is typical for this route at the moment.
San Diego to South Carolina flights typically cost between $314 and $444 in October.The cheapest round-trip price found within the last 5 days was $320 on United Airlines (Oct 21-Oct 24).
How far ahead should I book a flight from San Diego to South Carolina?
The price you pay for your flight from San Diego to South Carolina may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 12, 2026.
See what other customers who have flown with Southwest,Delta, andUnited Airlines from San Diego to South Carolina have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Food
7.0
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from San Diego to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to South Carolina
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Complete your trip
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Find flights from San Diego to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and South Carolina flights
Browse other San Diego and South Carolina flight options. Last updated on September 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to South Carolina flights
Consider these flights traveling from San Diego to South Carolina.
Top 5 airlines flying from San Diego to South Carolina
Discover the top 5 airlines that operate flights from San Diego to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$134 | Average$282 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$248 | Average$528 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$298 | Average$495 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$308 | Average$514 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$326 | Average$511 | FlexibilityNo cancel fee | On-time69% |